43 results on '"Zaharieva E"'
Search Results
2. Multi-wavelength picture of the misaligned BL Lac object 3C 371
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Otero-Santos, J., Raiteri, C. M., Tramacere, A., Pedrosa, J. Escudero, Acosta-Pulido, J. A., Carnerero, M. I., Villata, M., Agudo, I., Rahimov, I. A., Andreeva, T. S., Ivanov, D. V., Marchili, N., Righini, S., Giroletti, M., Gurwell, M. A., Savchenko, S. S., Carosati, D., Chen, W. P., Kurtanidze, S. O., Joner, M. D., Semkov, E., Pursimo, T., Benítez, E., Damljanovic, G., Andreuzzi, G., Apolonio, G., Borman, G. A., Bozhilov, V., Galindo-Guil, F. J., Grishina, T. S., Hagen-Thorn, V. A., Hiriart, D., Hsiao, H. Y., Ibryamov, S., Ivanidze, R. Z., Kimeridze, G. N., Kopatskaya, E. N., Kurtanidze, O. M., Larionov, V. M., Larionova, E. G., Larionova, L. V., Minev, M., Morozova, D. A., Nikolashvili, M. G., Ovcharov, E., Sigua, L. A., Stojanovic, M., Troitskiy, I. S., Troitskaya, Yu. V., Tsai, A., Valcheva, A., Vasilyev, A. A., Vince, O., Zaharieva, E., and Zhovtan, A. V.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
The BL Lac object 3C 371 is one of the targets that are regularly monitored by the Whole Earth Blazar Telescope (WEBT) Collaboration to study blazar variability on both short and long timescales. We aim to evaluate the long-term multiwavelength (MWL) behaviour of 3C 371, comparing it with the results derived for its optical emission in our previous study. For this, we make use of the multi-band campaigns organized by the WEBT Collaboration in optical and radio between January 2018 and December 2020, and of public data from Swift and Fermi satellites and the MOJAVE Very Large Interferometry programme. We evaluate the variability shown by the source in each band with the amplitude variability quantification, as well as possible interband correlation using the z-Discrete Correlation Function. We also present a deep analysis of the optical-UV, X-ray and $\gamma$-ray spectral variability. With the MOJAVE data we perform a kinematics analysis, looking for components propagating along the jet, calculating its kinematics parameters. This set of parameters is later used for the interpretation of the source MWL behaviour, modelling the broadband spectral energy distribution (SED) of the source with theoretical blazar emission scenarios., Comment: Accepted in A&A, 23 pages, 15 figures
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- 2024
3. A wiggling filamentary jet at the origin of the blazar multi-wavelength behaviour
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Raiteri, C. M., Villata, M., Carnerero, M. I., Kurtanidze, S. O., Mirzaqulov, D. O., Benítez, E., Bonnoli, G., Carosati, D., Acosta-Pulido, J. A., Agudo, I., Andreeva, T. S., Apolonio, G., Bachev, R., Borman, G. A., Bozhilov, V., Brown, L. F., Carbonell, W., Casadio, C., Chen, W. P., Damljanovic, G., Ehgamberdiev, S. A., Elsaesser, D., Escudero, J., Feige, M., Fuentes, A., Gabellini, D., Gazeas, K., Giroletti, M., Grishina, T. S., Gupta, A. C., Gurwell, M. A., Hagen-Thorn, V. A., Hamed, G. M., Hiriart, D., Hodges, M., ivanidze, R. Z., Ivanov, D. V., Joner, M. D., Jorstad, S. G., Jovanovic, M. D., Kiehlmann, S., Kimeridze, G. N., Kopatskaya, E. N., Kovalev, Yu. A., Kovalev, Y. Y., Kurtanidze, O. M., Kurtenkov, A., Larionova, E. G., Lessing, A., Lin, H. C., López, J. M., Lorey, C., Ludwig, J., Marchili, N., Marchini, A., Marscher, A. P., Matsumoto, K., Max-Moerbeck, W., Mihov, B., Minev, M., Mingaliev, M. G., Modaressi, A., Morozova, D. A., Mortari, F., Mufakharov, T. V., Myserlis, I., Nikolashvili, M. G., Pearson, T. J., Popkov, A. V., Rahimov, I. A., Readhead, A. C. S., Reinhart, D., Reeves, R., Righini, S., Romanov, F. D., Savchenko, S. S., Semkov, E., Shishkina, E. V., Sigua, L. A., Slavcheva-Mihova, L., Sotnikova, Yu. V., Steineke, R., Stojanovic, M., Strigachev, A., Takey, A., Traianou, E., Troitskaya, Yu. V., Troitskiy, I. S., Tsai, A. L., Valcheva, A., Vasilyev, A. A., Verna, G., Vince, O., Vrontaki, K., Weaver, Z. R., Webb, J., Yuldoshev, Q. X., Zaharieva, E., and Zhovtan, A. V.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Blazars are beamed active galactic nuclei known for their strong multi-wavelength variability on timescales from years down to minutes. We aim to investigate the suitability of the twisting jet model presented in previous works to explain the multi-wavelength behaviour of BL Lacertae, the prototype of one of the blazar classes. According to this model, the jet is inhomogeneous, curved, and twisting, and the long-term variability is due to changes in the Doppler factor due to variations in the orientation of the jet-emitting regions. We analysed optical data of the source obtained during monitoring campaigns organised by the Whole Earth Blazar Telescope (WEBT) in 2019-2022, together with radio data from the WEBT and other teams, and gamma-ray data from the Fermi satellite. In this period, BL Lacertae underwent an extraordinary activity phase, reaching its historical optical and gamma-ray brightness maxima. The application of the twisting jet model to the source light curves allows us to infer the wiggling motion of the optical, radio, and gamma-ray jet-emitting regions. The optical-radio correlation shows that the changes in the radio viewing angle follow those in the optical viewing angle by about 120 days, and it suggests that the jet is composed of plasma filaments, which is in agreement with some radio high-resolution observations of other sources. The gamma-ray emitting region is found to be co-spatial with the optical one, and the analysis of the gamma-optical correlation is consistent with both the geometric interpretation and a synchrotron self-Compton (SSC) origin of the high-energy photons. We propose a geometric scenario where the jet is made up of a pair of emitting plasma filaments in a sort of double-helix curved rotating structure, whose wiggling motion produces changes in the Doppler beaming and can thus explain the observed multi-wavelength long-term variability., Comment: In press for A&A
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- 2024
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4. Optical variability of the blazar 3C 371: from minute to year timescales
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Otero-Santos, J., Raiteri, C. M., Acosta-Pulido, J. A., Carnerero, M. I., Villata, M., Savchenko, S. S., Carosati, D., Chen, W. P., Kurtanidze, S. O., Joner, M. D., Semkov, E., Pursimo, T., Benítez, E., Damljanovic, G., Apolonio, G., Borman, G. A., Bozhilov, V., Galindo-Guil, F. J., Grishina, T. S., Hagen-Thorn, V. A., Hiriart, D., Hsiao, H. Y., Ibryamov, S., Ivanidze, R. Z., Kimeridze, G. N., Kopatskaya, E. N., Kurtanidze, O. M., Larionov, V. M., Larionova, E. G., Larionova, L. V., Minev, M., Morozova, D. A., Nikolashvili, M. G., Ovcharov, E., Sigua, L. A., Stojanovic, M., Troitskiy, I. S., Troitskaya, Yu. V., Tsai, A., Valcheva, A., Vasilyev, A. A., Vince, O., Zaharieva, E., and Zhovtan, A. V.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The BL Lac object 3C 371 has been observed by the Transiting Exoplanet Survey Satellite (\textit{TESS}) for approximately a year, between July 2019 and July 2020, with an unmatched 2-minute observing cadence. In parallel, the Whole Earth Blazar Telescope (WEBT) Collaboration organized an extensive observing campaign, providing three years of continuous optical monitoring between 2018 and 2020. These datasets allow for a thorough investigation of the variability of the source. The goal of this study is evaluating the optical variability of 3C 371. Taking advantage of the remarkable cadence of \textit{TESS} data, we aim to characterize the intra-day variability (IDV) displayed by the source and identify its shortest variability timescale. With this estimate, constraints on the size of the emitting region and black hole mass can be calculated. Moreover, WEBT data is used to investigate long-term variability (LTV), including understanding spectral behaviour of the source and the polarization variability. Based on the derived characteristics, information on the origin of the variability on different timescales is extracted. We evaluated the variability applying the variability amplitude tool that quantifies how variable the emission is. Moreover, we employed common tools like ANOVA (ANalysis Of VAariance) tests, wavelet and power spectral density (PSD) analyses to characterize the shortest variability timescales present in the emission and the underlying noise affecting the data. Short- and long-term colour behaviours have been evaluated to understand the spectral behaviour of the source. The polarized emission was analyzed, studying its variability and possible rotation patterns of the electric vector position angle (EVPA). Flux distributions of IDV and LTV were also studied with the aim of linking the flux variations to turbulent and/or accretion disc related processes., Comment: Accepted in A&A, 20 pages, 19 figures
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- 2024
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5. The variability patterns of the TeV blazar PG 1553+113 from a decade of MAGIC and multi-band observations
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MAGIC Collaboration, Abe, H., Abe, S., Abhir, J., Acciari, V. A., Agudo, I., Aniello, T., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Arcaro, C., Artero, M., Asano, K., Baack, D., Babić, A., Baquero, A., de Almeida, U. Barres, Batković, I., Baxter, J., González, J. Becerra, Bernardini, E., Bernete, J., Berti, A., Besenrieder, J., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Bošnjak, Ž., Burelli, I., Busetto, G., Campoy-Ordaz, A., Carosi, A., Carosi, R., Carretero-Castrillo, M., Castro-Tirado, A. J., Chai, Y., Cifuentes, A., Cikota, S., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D'Amico, G., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Del Popolo, A., Delfino, M., Delgado, J., Mendez, C. Delgado, Depaoli, D., Di Pierro, F., Di Venere, L., Prester, D. Dominis, Donini, A., Dorner, D., Doro, M., Elsaesser, D., Emery, G., Escudero, J., Fariña, L., Fattorini, A., Foffano, L., Font, L., Fukami, S., Fukazawa, Y., López, R. J. García, Gasparyan, S., Gaug, M., Paiva, J. G. Giesbrecht, Giglietto, N., Giordano, F., Gliwny, P., Grau, R., Green, J. G., Hadasch, D., Hahn, A., Heckmann, L., Herrera, J., Hovatta, T., Hrupec, D., Hütten, M., Imazawa, R., Inada, T., Iotov, R., Ishio, K., Martínez, I. Jiménez, Jormanainen, J., Kerszberg, D., Kluge, G. W., Kobayashi, Y., Kouch, P. M., Kubo, H., Kushida, J., Lezáun, M. Láinez, Lamastra, A., Leone, F., Lindfors, E., Liodakis, I., Lombardi, S., Longo, F., López-Moya, M., López-Oramas, A., Loporchio, S., Lorini, A., Fraga, B. Machado de Oliveira, Majumdar, P., Makariev, M., Maneva, G., Mang, N., Manganaro, M., Mannheim, K., Mariotti, M., Martínez, M., Martínez-Chicharro, M., Mas-Aguilar, A., Mazin, D., Menchiari, S., Mender, S., Miceli, D., Miener, T., Miranda, J. M., Mirzoyan, R., González, M. Molero, Molina, E., Mondal, H. A., Moralejo, A., Morcuende, D., Nakamori, T., Nanci, C., Neustroev, V., Nigro, C., Nikolić, L., Nilsson, K., Nishijima, K., Ekoume, T. Njoh, Noda, K., Nozaki, S., Ohtani, Y., Okumura, A., Otero-Santos, J., Paiano, S., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J. M., Pavlović, D., Persic, M., Pihet, M., Pirola, G., Podobnik, F., Moroni, P. G. Prada, Prandini, E., Principe, G., Priyadarshi, C., Rhode, W., Ribó, M., Rico, J., Righi, C., Sahakyan, N., Saito, T., Satalecka, K., Saturni, F. G., Schleicher, B., Schmidt, K., Schmuckermaier, F., Schubert, J. L., Schweizer, T., Sciaccaluga, A., Sitarek, J., Spolon, A., Stamerra, A., Strišković, J., Strom, D., Suda, Y., Suutarinen, S., Tajima, H., Takeishi, R., Tavecchio, F., Temnikov, P., Terauchi, K., Terzić, T., Teshima, M., Tosti, L., Truzzi, S., Tutone, A., Ubach, S., van Scherpenberg, J., Ventura, S., Verguilov, V., Viale, I., Vigorito, C. F., Vitale, V., Walter, R., Wunderlich, C., Yamamoto, T., collaborators, MWL, Jermak, H., Steele, I. A., Smith, P. S., Blinov, D., Raiteri, C. M., Villata, M., Mirzaqulov, D. O., Kurtanidze, S. O., Carosati, D., Savchenko, S. S., Acosta-Pulido, J. A., Borman, G. A., Bozhilov, V., Carnerero, M. I., Chigladze, R. A., Damljanovic, G., Ehgamberdiev, S. A., Feige, M., Grishina, T. S., Gupta, A. C., Hagen-Thorn, V. A., Ibryamov, S., Ivanidze, R. Z., Jorstad, S. G., Kania, J., Kimeridze, G. N., Kopatskaya, E. N., Kopp, M., Kunkel, L., Kurtanidze, O. M., Larionov, V. M., Larionova, E. G., Larionova, L. V., Lorey, C., Marchini, A., Marscher, A. P., Minev, M., Morozova, D. A., Nikolashvili, M. G., Ovcharov, E., Reinhart, D., Sadun, A. C., Scherbantin, A., Schneider, L., Semkov, E., Sigua, L. A., Steineke, R., Troitskaya, Yu. V., Troitskiy, I. S., Valcheva, A., Vasilyev, A. A., Vince, O., Zaharieva, E., Zottmann, N., Kiehlmann, S., Readhead, A., Max-Moerbeck, W., Reeves, R. A., Sandrinelli, A., Ramazani, V. Fallah, Giroletti, M., Righini, S., Marchili, N., Patricelli, B., Ghirlanda, G., and Lico, R.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
PG 1553+113 is one of the few blazars with a convincing quasi-periodic emission in the gamma-ray band. The source is also a very high-energy (VHE; >100 GeV) gamma-ray emitter. To better understand its properties and identify the underlying physical processes driving its variability, the MAGIC Collaboration initiated a multiyear, multiwavelength monitoring campaign in 2015 involving the OVRO 40-m and Medicina radio telescopes, REM, KVA, and the MAGIC telescopes, Swift and Fermi satellites, and the WEBT network. The analysis presented in this paper uses data until 2017 and focuses on the characterization of the variability. The gamma-ray data show a (hint of a) periodic signal compatible with literature, but the X-ray and VHE gamma-ray data do not show statistical evidence for a periodic signal. In other bands, the data are compatible with the gamma-ray period, but with a relatively high p-value. The complex connection between the low and high-energy emission and the non-monochromatic modulation and changes in flux suggests that a simple one-zone model is unable to explain all the variability. Instead, a model including a periodic component along with multiple emission zones is required., Comment: Accepted for publication in Monthly Notices of the Royal Astronomical Society. 19 pages, 9 figures. Corresponding authors: Elisa Prandini, Antonio Stamerra, Talvikki Hovatta
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- 2024
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6. Multi-messenger characterization of Mrk 501 during historically low X-ray and $\gamma$-ray activity
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MAGIC collaboration, Abe, H., Abe, S., Acciari, V. A., Agudo, I., Aniello, T., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Arcaro, C., Artero, M., Asano, K., Baack, D., Babić, A., Baquero, A., de Almeida, U. Barres, Barrio, J. A., Batković, I., Baxter, J., González, J. Becerra, Bednarek, W., Bernardini, E., Bernardos, M., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Bošnjak, Ž., Burelli, I., Busetto, G., Carosi, R., Carretero-Castrillo, M., Castro-Tirado, A. J., Ceribella, G., Chai, Y., Chilingarian, A., Cikota, S., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D'Amico, G., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Del Popolo, A., Delfino, M., Delgado, J., Mendez, C. Delgado, Depaoli, D., Di Pierro, F., Di Venere, L., Espiñeira, E. Do Souto, Prester, D. Dominis, Donini, A., Dorner, D., Doro, M., Elsaesser, D., Emery, G., Escudero, J., Ramazani, V. Fallah, Fariña, L., Fattorini, A., Foffano, L., Font, L., Fruck, C., Fukami, S., Fukazawa, Y., López, R. J. García, Garczarczyk, M., Gasparyan, S., Gaug, M., Paiva, J. G. Giesbrecht, Giglietto, N., Giordano, F., Gliwny, P., Godinović, N., Grau, R., Green, D., Green, J. G., Hadasch, D., Hahn, A., Hassan, T., Heckmann, L., Herrera, J., Hrupec, D., Hütten, M., Imazawa, R., Inada, T., Iotov, R., Ishio, K., Martínez, I. Jiménez, Jormanainen, J., Kerszberg, D., Kobayashi, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Linhoff, L., Lombardi, S., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Lorini, A., Lyard, E., Fraga, B. Machado de Oliveira, Majumdar, P., Makariev, M., Maneva, G., Mang, N., Manganaro, M., Mangano, S., Mannheim, K., Mariotti, M., Martínez, M., Mas-Aguilar, A., Mazin, D., Menchiari, S., Mender, S., Mićanović, S., Miceli, D., Miener, T., Miranda, J. M., Mirzoyan, R., Molina, E., Mondal, H. A., Moralejo, A., Morcuende, D., Moreno, V., Nakamori, T., Nanci, C., Nava, L., Neustroev, V., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Nishijima, K., Ekoume, T. Njoh, Noda, K., Nozaki, S., Ohtani, Y., Oka, T., Okumura, A., Otero-Santos, J., Paiano, S., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J. M., Pavletić, L., Persic, M., Pihet, M., Pirola, G., Podobnik, F., Moroni, P. G. Prada, Prandini, E., Principe, G., Priyadarshi, C., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Sahakyan, N., Saito, T., Sakurai, S., Satalecka, K., Saturni, F. G., Schleicher, B., Schmidt, K., Schmuckermaier, F., Schubert, J. L., Schweizer, T., Sitarek, J., Sliusar, V., Sobczynska, D., Spolon, A., Stamerra, A., Strišković, J., Strom, D., Strzys, M., Suda, Y., Surić, T., Tajima, H., Takahashi, M., Takeishi, R., Tavecchio, F., Temnikov, P., Terauchi, K., Terzić, T., Teshima, M., Tosti, L., Truzzi, S., Tutone, A., Ubach, S., van Scherpenberg, J., Acosta, M. Vazquez, Ventura, S., Verguilov, V., Viale, I., Vigorito, C. F., Vitale, V., Vovk, I., Walter, R., Will, M., Wunderlich, C., Yamamoto, T., Zarić, D., groups, Other, collaborations, Cerruti, M., Acosta-Pulido, J. A., Apolonio, G., Bachev, R., Baloković, M., Benítez, E., Björklund, I., Bozhilov, V., Brown, L. F., Bugg, A., Carbonell, W., Carnerero, M. I., Carosati, D., Casadio, C., Chamani, W., Chen, W. P., Chigladze, R. A., Damljanovic, G., Epps, K., Erkenov, A., Feige, M., Finke, J., Fuentes, A., Gazeas, K., Giroletti, M., Grishina, T. S., Gupta, A. C., Gurwell, M. A., Heidemann, E., Hiriart, D., Hou, W. J., Hovatta, T., Ibryamov, S., Joner, M. D., Jorstad, S. G., Kania, J., Kiehlmann, S., Kimeridze, G. N., Kopatskaya, E. N., Kopp, M., Korte, M., Kotas, B., Koyama, S., Kramer, J. A., Kunkel, L., Kurtanidze, S. O., Kurtanidze, O. M., Lähteenmäki, A., López, J. M., Larionov, V. M., Larionova, E. G., Larionova, L. V., Leto, C., Lorey, C., Mújica, R., Madejski, G. M., Marchili, N., Marscher, A. P., Minev, M., Modaressi, A., Morozova, D. A., Mufakharov, T., Myserlis, I., Nikiforova, A. A., Nikolashvili, M. G., Ovcharov, E., Perri, M., Raiteri, C. M., Readhead, A. C. S., Reimer, A., Reinhart, D., Righini, S., Rosenlehner, K., Sadun, A. C., Savchenko, S. S., Scherbantin, A., Schneider, L., Schoch, K., Seifert, D., Semkov, E., Sigua, L. A., Singh, C., Sola, P., Sotnikova, Y., Spencer, M., Steineke, R., Stojanovic, M., Strigachev, A., Tornikoski, M., Traianou, E., Tramacere, A., Troitskaya, Yu. V., Troitskiy, I. S., Trump, J. B., Tsai, A., Valcheva, A., Vasilyev, A. A., Verrecchia, F., Villata, M., Vince, O., Vrontaki, K., Weaver, Z. R., Zaharieva, E., and Zottmann, N.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We study the broadband emission of Mrk 501 using multi-wavelength observations from 2017 to 2020 performed with a multitude of instruments, involving, among others, MAGIC, Fermi-LAT, NuSTAR, Swift, GASP-WEBT, and OVRO. Mrk 501 showed an extremely low broadband activity, which may help to unravel its baseline emission. Nonetheless, significant flux variations are detected at all wavebands, with the highest occurring at X-rays and very-high-energy (VHE) $\gamma$-rays. A significant correlation ($>$3$\sigma$) between X-rays and VHE $\gamma$-rays is measured, supporting leptonic scenarios to explain the variable parts of the emission, also during low activity. This is further supported when we extend our data from 2008 to 2020, and identify, for the first time, significant correlations between Swift-XRT and Fermi-LAT. We additionally find correlations between high-energy $\gamma$-rays and radio, with the radio lagging by more than 100 days, placing the $\gamma$-ray emission zone upstream of the radio-bright regions in the jet. Furthermore, Mrk 501 showed a historically low activity in X-rays and VHE $\gamma$-rays from mid-2017 to mid-2019 with a stable VHE flux ($>$0.2 TeV) of 5% the emission of the Crab Nebula. The broadband spectral energy distribution (SED) of this 2-year-long low-state, the potential baseline emission of Mrk 501, can be characterized with one-zone leptonic models, and with (lepto)-hadronic models fulfilling neutrino flux constraints from IceCube. We explore the time evolution of the SED towards the low-state, revealing that the stable baseline emission may be ascribed to a standing shock, and the variable emission to an additional expanding or traveling shock., Comment: 55 pages, 30 figures, 14 tables, accepted by APJS. Corresponding authors are L. Heckmann, D. Paneque, S. Gasparyan, M. Cerruti, and N. Sahakyan
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- 2022
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7. Investigation of the correlation patterns and the Compton dominance variability of Mrk 421 in 2017
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MAGIC Collaboration, Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Artero, M., Asano, K., Babić, A., Baquero, A., de Almeida, U. Barres, Barrio, J. A., Batković, I., González, J. Becerra, Bednarek, W., Bellizzi, L., Bernardini, E., Bernardos, M., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Blanch, O., Bošnjak, Ž., Busetto, G., Carosi, R., Ceribella, G., Cerruti, M., Chai, Y., Chilingarian, A., Cikota, S., Colak, S. M., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D'Amico, G., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Mendez, C. Delgado, Depaoli, D., Di Pierro, F., Di Venere, L., Espiñeira, E. Do Souto, Prester, D. Dominis, Donini, A., Doro, M., Ramazani, V. Fallah, Fattorini, A., Ferrara, G., Fonseca, M. V., Font, L., Fruck, C., Fukami, S., López, R. J. García, Garczarczyk, M., Gasparyan, S., Gaug, M., Giglietto, N., Giordano, F., Gliwny, P., Godinović, N., Green, J. G., Green, D., Hadasch, D., Hahn, A., Heckmann, L., Herrera, J., Hoang, J., Hrupec, D., Hütten, M., Inada, T., Inoue, S., Ishio, K., Iwamura, Y., Jiménez, I., Jormanainen, J., Jouvin, L., Kajiwara, Y., Karjalainen, M., Kerszberg, D., Kobayashi, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Fraga, B. Machado de Oliveira, Maggio, C., Majumdar, P., Makariev, M., Mallamaci, M., Maneva, G., Manganaro, M., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Menchiari, S., Mender, S., Mićanović, S., Miceli, D., Miener, T., Minev, M., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Morcuende, D., Moreno, V., Moretti, E., Neustroev, V., Nigro, C., Nilsson, K., Nishijima, K., Noda, K., Nozaki, S., Ohtani, Y., Oka, T., Otero-Santos, J., Paiano, S., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J. M., Pavletić, L., Peñil, P., Perennes, C., Persic, M., Moroni, P. G. Prada, Prandini, E., Priyadarshi, C., Puljak, I., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Sahakyan, N., Saito, T., Sakurai, S., Satalecka, K., Saturni, F. G., Schmidt, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Spolon, A., Stamerra, A., Strom, D., Strzys, M., Suda, Y., Surić, T., Takahashi, M., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Tosti, L., Truzzi, S., Tutone, A., Ubach, S., van Scherpenberg, J., Vanzo, G., Acosta, M. Vazquez, Ventura, S., Verguilov, V., Vigorito, C. F., Vitale, V., Vovk, I., Will, M., Wunderlich, C., Zarić, D., Collaboration, FACT, Baack, D., Balbo, M., Biederbeck, N., Biland, A., Bretz, T., Buss, J., Dorner, D., Eisenberger, L., Elsaesser, D., Hildebrand, D., Iotov, R., Mannheim, K., Neise, D., Noethe, M., Paravac, A., Rhode, W., Schleicher, B., Sliusar, V., Walter, R., groups, Other, collaborations, D'Ammando, F., Horan, D., Lien, A. Y., Baloković, M., Madejski, G. M., Perri, M., Verrecchia, F., Leto, C., Lähteenmäki, A., Tornikoski, M., Ramakrishnan, V., Järvelä, E., Vera, R. J. C., Villata, M., Raiteri, C. M., Gupta, A. C., Pandey, A., Fuentes, A., Agudo, I., Casadio, C., Semkov, E., Ibryamov, S., Marchini, A., Bachev, R., Strigachev, A., Ovcharov, E., Bozhilov, V., Valcheva, A., Zaharieva, E., Damljanovic, G., Vince, O., Larionov, V. M., Borman, G. A., Grishina, T. S., Hagen-Thorn, V. A., Kopatskaya, E. N., Larionova, E. G., Larionova, L. V., Morozova, D. A., Nikiforova, A. A., Savchenko, S. S., Troitskiy, I. S., Troitskaya, Y. V., Vasilyev, A. A., Merkulova, O. A., Chen, W. P., Samal, M., Lin, H. C., Moody, J. W., Sadun, A. C., Jorstad, S. G., Marscher, A. P., Weaver, Z. R., Feige, M., Kania, J., Kopp, M., Kunkel, L., Reinhart, D., Scherbantin, A., Schneider, L., Lorey, C., Acosta-Pulido, J. A., Carnerero, M. I., Carosati, D., Kurtanidze, S. O., Kurtanidze, O. M., Nikolashvili, M. G., Chanishvili, R. G., Chigladze, R. A., Ivanidze, R. Z., Kimeridze, G. N., Sigua, L. A., Joner, M. D., Spencer, M., Giroletti, M., Marchili, N., Righini, S., Rizzi, N., and Bonnoli, G.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We present a detailed characterisation and theoretical interpretation of the broadband emission of the paradigmatic TeV blazar Mrk 421, with special focus on the multi-band flux correlations. The dataset has been collected through an extensive multiwavelength campaign organised between 2016 December and 2017 June. The instruments involved are MAGIC, FACT, Fermi-LAT, Swift, GASP-WEBT, OVRO, Medicina and Mets\"ahovi. Additionally, four deep exposures (several hours long) with simultaneous MAGIC and NuSTAR observations allowed a precise measurement of the falling segments of the two spectral components. The very-high-energy (VHE; E > 100 GeV) gamma rays and X-rays are positively correlated at zero time lag, but the strength and characteristics of the correlation change substantially across the various energy bands probed. The VHE versus X-ray fluxes follow different patterns, partly due to substantial changes in the Compton dominance during a few days without a simultaneous increase in the X-ray flux (i.e. orphan gamma-ray activity). Studying the broadband spectral energy distribution (SED) during the days including NuSTAR observations, we show that these changes can be explained within a one-zone leptonic model with a blob that increases its size over time. Our multi-band correlation study also hints at an anti-correlation between UV/optical and X-ray at a significance higher than 3 sigmas. A VHE flare observed on 2017 February 4 shows gamma-ray variability on multi-hour timescales, with a factor 10 increase in the TeV flux but only a moderate increase in the keV flux. The related broadband SED is better described by a two-zone leptonic scenario rather than by a one-zone scenario. We find that the flare can be produced by the appearance of a compact second blob populated by high energetic electrons spanning a narrow range of Lorentz factors., Comment: 38 pages, 23 figures, accepted for publication in Astronomy and Astrophysics. Corresponding authors: Axel Arbet-Engels, David Paneque
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- 2021
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8. Multi-Wavelength Variability of BL Lacertae Measured with High Time Resolution
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Weaver, Zachary R., Williamson, K. E., Jorstad, S. G., Marscher, A. P., Larionov, V. M., Raiteri, C. M., Villata, M., Acosta-Pulido, J. A., Bachev, R., Baida, G. V., Balonek, T. J., Benitez, E., Borman, G. A., Bozhilov, V., Carnerero, M. I., Carosati, D., Chen, W. P., Damljanovic, G., Dhiman, V., Dougherty, D. J., Ehgamberdiev, S. A., Grishina, T. S., Gupta, A. C., Hart, M., Hiriart, D., Hsiao, H. Y., Ibryamov, S., Joner, M., Kimeridze, G. N., Kopatskaya, E. N., Kurtanidze, O. M., Kurtanidze, S. O., Larionova, E. G., Matsumoto, K., Matsumura, R., Minev, M., Mirzaqulov, D. O., Morozova, D. A., Nikiforova, A. A., Nikolashvili, M. G., Ovcharov, E., Rizzi, N., Sadun, A., Savchenko, S. S., Semkov, E., Slater, J. J., Smith, K. L., Stojanovic, M., Strigachev, A., Troitskaya, Yu. V., Troitsky, I. S., Tsai, A. L., Vince, O., Valcheva, A., Vasilyev, A. A., Zaharieva, E., and Zhovtan, A. V.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
In an effort to locate the sites of emission at different frequencies and physical processes causing variability in blazar jets, we have obtained high time-resolution observations of BL Lacertae over a wide wavelength range: with the \emph{Transiting Exoplanet Survey Satellite} (TESS) at 6,000-10,000 \AA\ with 2-minute cadence; with the Neil Gehrels \emph{Swift} satellite at optical, UV, and X-ray bands; with the Nuclear Spectroscopic Telescope Array at hard X-ray bands; with the \emph{Fermi} Large Area Telescope at $\gamma$-ray energies; and with the Whole Earth Blazar Telescope for measurement of the optical flux density and polarization. All light curves are correlated, with similar structure on timescales from hours to days. The shortest timescale of variability at optical frequencies observed with TESS is $\sim 0.5$ hr. The most common timescale is $13\pm1$~hr, comparable with the minimum timescale of X-ray variability, 14.5 hr. The multi-wavelength variability properties cannot be explained by a change solely in the Doppler factor of the emitting plasma. The polarization behavior implies that there are both ordered and turbulent components to the magnetic field in the jet. Correlation analysis indicates that the X-ray variations lag behind the $\gamma$-ray and optical light curves by up to $\sim 0.4$ days. The timescales of variability, cross-frequency lags, and polarization properties can be explained by turbulent plasma that is energized by a shock in the jet and subsequently loses energy to synchrotron and inverse Compton radiation in a magnetic field of strength $\sim3$ G, Comment: 33 pages, 25 figures, 14 tables. Accepted to ApJ
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- 2020
9. Rapid quasi-periodic oscillations in the relativistic jet of BL Lacertae
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Jorstad, S. G., Marscher, A. P., Raiteri, C. M., Villata, M., Weaver, Z. R., Zhang, H., Dong, L., Gómez, J. L., Perel, M. V., Savchenko, S. S., Larionov, V. M., Carosati, D., Chen, W. P., Kurtanidze, O. M., Marchini, A., Matsumoto, K., Mortari, F., Aceti, P., Acosta-Pulido, J. A., Andreeva, T., Apolonio, G., Arena, C., Arkharov, A., Bachev, R., Banfi, M., Bonnoli, G., Borman, G. A., Bozhilov, V., Carnerero, M. I., Damljanovic, G., Ehgamberdiev, S. A., Elsässer, D., Frasca, A., Gabellini, D., Grishina, T. S., Gupta, A. C., Hagen-Thorn, V. A., Hallum, M. K., Hart, M., Hasuda, K., Hemrich, F., Hsiao, H. Y., Ibryamov, S., Irsmambetova, T. R., Ivanov, D. V., Joner, M. D., Kimeridze, G. N., Klimanov, S. A., Knött, J., Kopatskaya, E. N., Kurtanidze, S. O., Kurtenkov, A., Kuutma, T., Larionova, E. G., Leonini, S., Lin, H. C., Lorey, C., Mannheim, K., Marino, G., Minev, M., Mirzaqulov, D. O., Morozova, D. A., Nikiforova, A. A., Nikolashvili, M. G., Ovcharov, E., Papini, R., Pursimo, T., Rahimov, I., Reinhart, D., Sakamoto, T., Salvaggio, F., Semkov, E., Shakhovskoy, D. N., Sigua, L. A., Steineke, R., Stojanovic, M., Strigachev, A., Troitskaya, Y. V., Troitskiy, I. S., Tsai, A., Valcheva, A., Vasilyev, A. A., Vince, O., Waller, L., Zaharieva, E., and Chatterjee, R.
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- 2022
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10. Optical variability of the blazar 3C 371: From minute to year timescales
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Otero-Santos, J., primary, Raiteri, C.M., additional, Acosta-Pulido, J.A., additional, Carnerero, M.I., additional, Villata, M., additional, Savchenko, S., additional, Carosati, D., additional, Chen, W.P., additional, Kurtanidze, S.O., additional, Joner, M.D., additional, Semkov, E., additional, Pursimo, T., additional, Benítez, E., additional, Damljanovic, G., additional, Apolonio, G., additional, Borman, G.A., additional, Bozhilov, V., additional, Galindo-Guil, F.J., additional, Grishina, T.S., additional, Hagen-Thorn, V.A., additional, Hiriart, D., additional, Hsiao, H.Y., additional, Ibryamov, S., additional, Ivanidze, R.Z., additional, Kimeridze, G.N., additional, Kopatskaya, E.N., additional, Kurtanidze, O.M., additional, Larionov, V.M., additional, Larionova, E.G., additional, Larionova, L.V., additional, Minev, M., additional, Morozova, D.A., additional, Nikolashvili, M.G., additional, Ovcharov, E., additional, Sigua, L.A., additional, Stojanovic, M., additional, Troitskiy, I.S., additional, Troitskaya, V. Yu., additional, Tsai, A., additional, Valcheva, A., additional, Vasilyev, A., additional, Vince, O., additional, Zaharieva, E., additional, and Zhovtan, A.V., additional
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- 2024
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11. Multimessenger Characterization of Markarian 501 during Historically Low X-Ray and γ-Ray Activity
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Abe, H., primary, Abe, S., additional, Acciari, V. A., additional, Agudo, I., additional, Aniello, T., additional, Ansoldi, S., additional, Antonelli, L. A., additional, Arbet-Engels, A., additional, Arcaro, C., additional, Artero, M., additional, Asano, K., additional, Baack, D., additional, Babić, A., additional, Baquero, A., additional, de Almeida, U. Barres, additional, Barrio, J. A., additional, Batković, I., additional, Baxter, J., additional, Becerra González, J., additional, Bednarek, W., additional, Bernardini, E., additional, Bernardos, M., additional, Berti, A., additional, Besenrieder, J., additional, Bhattacharyya, W., additional, Bigongiari, C., additional, Biland, A., additional, Blanch, O., additional, Bonnoli, G., additional, Bošnjak, Ž., additional, Burelli, I., additional, Busetto, G., additional, Carosi, R., additional, Carretero-Castrillo, M., additional, Castro-Tirado, A. J., additional, Ceribella, G., additional, Chai, Y., additional, Chilingarian, A., additional, Cikota, S., additional, Colombo, E., additional, Contreras, J. L., additional, Cortina, J., additional, Covino, S., additional, D’Amico, G., additional, D’Elia, V., additional, Da Vela, P., additional, Dazzi, F., additional, De Angelis, A., additional, De Lotto, B., additional, Del Popolo, A., additional, Delfino, M., additional, Delgado, J., additional, Delgado Mendez, C., additional, Depaoli, D., additional, Di Pierro, F., additional, Di Venere, L., additional, Souto Espiñeira, E. Do, additional, Dominis Prester, D., additional, Donini, A., additional, Dorner, D., additional, Doro, M., additional, Elsaesser, D., additional, Emery, G., additional, Escudero, J., additional, Fallah Ramazani, V., additional, Fariña, L., additional, Fattorini, A., additional, Foffano, L., additional, Font, L., additional, Fruck, C., additional, Fukami, S., additional, Fukazawa, Y., additional, García López, R. J., additional, Garczarczyk, M., additional, Gasparyan, S., additional, Gaug, M., additional, Giesbrecht Paiva, J. G., additional, Giglietto, N., additional, Giordano, F., additional, Gliwny, P., additional, Godinović, N., additional, Grau, R., additional, Green, D., additional, Green, J. G., additional, Hadasch, D., additional, Hahn, A., additional, Hassan, T., additional, Heckmann, L., additional, Herrera, J., additional, Hrupec, D., additional, Hütten, M., additional, Imazawa, R., additional, Inada, T., additional, Iotov, R., additional, Ishio, K., additional, Jiménez Martínez, I., additional, Jormanainen, J., additional, Kerszberg, D., additional, Kobayashi, Y., additional, Kubo, H., additional, Kushida, J., additional, Lamastra, A., additional, Lelas, D., additional, Leone, F., additional, Lindfors, E., additional, Linhoff, L., additional, Lombardi, S., additional, Longo, F., additional, López-Coto, R., additional, López-Moya, M., additional, López-Oramas, A., additional, Loporchio, S., additional, Lorini, A., additional, Lyard, E., additional, Machado de Oliveira Fraga, B., additional, Majumdar, P., additional, Makariev, M., additional, Maneva, G., additional, Mang, N., additional, Manganaro, M., additional, Mangano, S., additional, Mannheim, K., additional, Mariotti, M., additional, Martínez, M., additional, Mas-Aguilar, A., additional, Mazin, D., additional, Menchiari, S., additional, Mender, S., additional, Mićanović, S., additional, Miceli, D., additional, Miener, T., additional, Miranda, J. M., additional, Mirzoyan, R., additional, Molina, E., additional, Mondal, H. A., additional, Moralejo, A., additional, Morcuende, D., additional, Moreno, V., additional, Nakamori, T., additional, Nanci, C., additional, Nava, L., additional, Neustroev, V., additional, Nievas Rosillo, M., additional, Nigro, C., additional, Nilsson, K., additional, Nishijima, K., additional, Njoh Ekoume, T., additional, Noda, K., additional, Nozaki, S., additional, Ohtani, Y., additional, Oka, T., additional, Okumura, A., additional, Otero-Santos, J., additional, Paiano, S., additional, Palatiello, M., additional, Paneque, D., additional, Paoletti, R., additional, Paredes, J. M., additional, Pavletić, L., additional, Persic, M., additional, Pihet, M., additional, Pirola, G., additional, Podobnik, F., additional, Moroni, P. G. Prada, additional, Prandini, E., additional, Principe, G., additional, Priyadarshi, C., additional, Rhode, W., additional, Ribó, M., additional, Rico, J., additional, Righi, C., additional, Rugliancich, A., additional, Sahakyan, N., additional, Saito, T., additional, Sakurai, S., additional, Satalecka, K., additional, Saturni, F. G., additional, Schleicher, B., additional, Schmidt, K., additional, Schmuckermaier, F., additional, Schubert, J. L., additional, Schweizer, T., additional, Sitarek, J., additional, Sliusar, V., additional, Sobczynska, D., additional, Spolon, A., additional, Stamerra, A., additional, Strišković, J., additional, Strom, D., additional, Strzys, M., additional, Suda, Y., additional, Surić, T., additional, Tajima, H., additional, Takahashi, M., additional, Takeishi, R., additional, Tavecchio, F., additional, Temnikov, P., additional, Terauchi, K., additional, Terzić, T., additional, Teshima, M., additional, Tosti, L., additional, Truzzi, S., additional, Tutone, A., additional, Ubach, S., additional, van Scherpenberg, J., additional, Acosta, M. Vazquez, additional, Ventura, S., additional, Verguilov, V., additional, Viale, I., additional, Vigorito, C. F., additional, Vitale, V., additional, Vovk, I., additional, Walter, R., additional, Will, M., additional, Wunderlich, C., additional, Yamamoto, T., additional, Zarić, D., additional, Cerruti, M., additional, Acosta-Pulido, J. A., additional, Apolonio, G., additional, Bachev, R., additional, Baloković, M., additional, Benítez, E., additional, Björklund, I., additional, Bozhilov, V., additional, Brown, L. F., additional, Bugg, A., additional, Carbonell, W., additional, Carnerero, M. I., additional, Carosati, D., additional, Casadio, C., additional, Chamani, W., additional, Chen, W. P., additional, Chigladze, R. A., additional, Damljanovic, G., additional, Epps, K., additional, Erkenov, A., additional, Feige, M., additional, Finke, J., additional, Fuentes, A., additional, Gazeas, K., additional, Giroletti, M., additional, Grishina, T. S., additional, Gupta, A. C., additional, Gurwell,, M. A., additional, Heidemann, E., additional, Hiriart, D., additional, Hou, W. J., additional, Hovatta, T., additional, Ibryamov, S., additional, Joner, M. D., additional, Jorstad, S. G., additional, Kania, J., additional, Kiehlmann, S., additional, Kimeridze, G. N., additional, Kopatskaya, E. N., additional, Kopp, M., additional, Korte, M., additional, Kotas, B., additional, Koyama, S., additional, Kramer, J. A., additional, Kunkel, L., additional, Kurtanidze, S. O., additional, Kurtanidze, O. M., additional, Lähteenmäki, A., additional, López, J. M., additional, Larionov, V. M., additional, Larionova, E. G., additional, Larionova, L. V., additional, Leto, C., additional, Lorey, C., additional, Mújica, R., additional, Madejski, G. M., additional, Marchili, N., additional, Marscher, A. P., additional, Minev, M., additional, Modaressi, A., additional, Morozova, D. A., additional, Mufakharov, T., additional, Myserlis, I., additional, Nikiforova, A. A., additional, Nikolashvili, M. G., additional, Ovcharov, E., additional, Perri, M., additional, Raiteri, C. M., additional, Readhead, A. C. S., additional, Reimer, A., additional, Reinhart, D., additional, Righini, S., additional, Rosenlehner, K., additional, Sadun, A. C., additional, Savchenko, S. S., additional, Scherbantin, A., additional, Schneider, L., additional, Schoch, K., additional, Seifert, D., additional, Semkov, E., additional, Sigua, L. A., additional, Singh, C., additional, Sola, P., additional, Sotnikova, Y., additional, Spencer, M., additional, Steineke, R., additional, Stojanovic, M., additional, Strigachev, A., additional, Tornikoski, M., additional, Traianou, E., additional, Tramacere, A., additional, Troitskaya, Yu. V., additional, Troitskiy, I. S., additional, Trump, J. B., additional, Tsai, A., additional, Valcheva, A., additional, Vasilyev, A. A., additional, Verrecchia, F., additional, Villata, M., additional, Vince, O., additional, Vrontaki, K., additional, Weaver, Z. R., additional, Zaharieva, E., additional, and Zottmann, N., additional
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- 2023
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12. The optical behaviour of BL Lacertae at its maximum brightness levels: a blend of geometry and energetics
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Raiteri, C M, primary, Villata, M, additional, Jorstad, S G, additional, Marscher, A P, additional, Acosta Pulido, J A, additional, Carosati, D, additional, Chen, W P, additional, Joner, M D, additional, Kurtanidze, S O, additional, Lorey, C, additional, Marchini, A, additional, Matsumoto, K, additional, Mirzaqulov, D O, additional, Savchenko, S S, additional, Strigachev, A, additional, Vince, O, additional, Aceti, P, additional, Apolonio, G, additional, Arena, C, additional, Arkharov, A, additional, Bachev, R, additional, Bader, N, additional, Banfi, M, additional, Bonnoli, G, additional, Borman, G A, additional, Bozhilov, V, additional, Brown, L F, additional, Carbonell, W, additional, Carnerero, M I, additional, Damljanovic, G, additional, Dhiman, V, additional, Ehgamberdiev, S A, additional, Elsaesser, D, additional, Feige, M, additional, Gabellini, D, additional, Galán, D, additional, Galli, G, additional, Gaur, H, additional, Gazeas, K, additional, Grishina, T S, additional, Gupta, A C, additional, Hagen-Thorn, V A, additional, Hallum, M K, additional, Hart, M, additional, Hasuda, K, additional, Heidemann, K, additional, Horst, B, additional, Hou, W-J, additional, Ibryamov, S, additional, Ivanidze, R Z, additional, Jovanovic, M D, additional, Kimeridze, G N, additional, Kishore, S, additional, Klimanov, S, additional, Kopatskaya, E N, additional, Kurtanidze, O M, additional, Kushwaha, P, additional, Lane, D J, additional, Larionova, E G, additional, Leonini, S, additional, Lin, H C, additional, Mannheim, K, additional, Marino, G, additional, Minev, M, additional, Modaressi, A, additional, Morozova, D A, additional, Mortari, F, additional, Nazarov, S V, additional, Nikolashvili, M G, additional, Otero Santos, J, additional, Ovcharov, E, additional, Papini, R, additional, Pinter, V, additional, Privitera, C A, additional, Pursimo, T, additional, Reinhart, D, additional, Roberts, J, additional, Romanov, F D, additional, Rosenlehner, K, additional, Sakamoto, T, additional, Salvaggio, F, additional, Schoch, K, additional, Semkov, E, additional, Seufert, J, additional, Shakhovskoy, D, additional, Sigua, L A, additional, Singh, C, additional, Steineke, R, additional, Stojanovic, M, additional, Tripathi, T, additional, Troitskaya, Y V, additional, Troitskiy, I S, additional, Tsai, A, additional, Valcheva, A, additional, Vasilyev, A A, additional, Vrontaki, K, additional, Weaver, Z R, additional, Wooley, J H F, additional, Zaharieva, E, additional, and Zhovtan, A V, additional
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- 2023
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13. ACTIVATION OF HUMAN FIBROBLASTS BY CHRONIC RADIATION RATHER THAN ACUTE RADIATION
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Shimura, T, primary, Zaharieva, E, additional, Sasatani, M, additional, Kawai, H, additional, Kamiya, K, additional, and Ushiyama, A, additional
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- 2022
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14. Multiwavelength Observations of the Blazar VER J0521+211 during an Elevated TeV Gamma-Ray State
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Abe, H., Abe, S., Acciari, V. A., Agudo, I., Aniello, T., Ansoldi, S., Antonelli, L. A., Arbet Engels, A., Arcaro, C., Artero, M., Asano, K., Baack, D., Babić, A., Baquero, A., Barres de Almeida, U., Barrio, J. A., Batković, I., Baxter, J., Becerra González, J., Bednarek, W., Bernardini, E., Bernardos, M., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Bošnjak, Ž., Burelli, I., Busetto, G., Carosi, R., Carretero-Castrillo, M., Castro-Tirado, A. J., Ceribella, G., Chai, Y., Chilingarian, A., Cikota, S., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D'Amico, G., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Del Popolo, A., Delfino, M., Delgado, J., Delgado Mendez, C., Depaoli, D., Di Pierro, F., Di Venere, L., Do Souto Espiñeira, E., Dominis Prester, D., Donini, A., Dorner, D., Doro, M., Elsaesser, D., Emery, G., Escudero, J., Fallah Ramazani, V., Fariña, L., Fattorini, A., Foffano, L., Font, L., Fruck, C., Fukami, S., Fukazawa, Y., García López, R. J., Garczarczyk, M., Gasparyan, S., Gaug, M., Giesbrecht Paiva, J. G., Giglietto, N., Giordano, F., Gliwny, P., Godinović, N., Grau, R., Green, D., Green, J. G., Hadasch, D., Hahn, A., Hassan, T., Heckmann, L., Herrera, J., Hrupec, D., Hütten, M., Imazawa, R., Inada, T., Iotov, R., Ishio, K., Jiménez Martínez, I., Jormanainen, J., Kerszberg, D., Kobayashi, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Linhoff, L., Lombardi, S., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Lorini, A., Lyard, E., Machado de Oliveira Fraga, B., Majumdar, P., Makariev, M., Maneva, G., Mang, N., Manganaro, M., Mangano, S., Mannheim, K., Mariotti, M., Martínez, M., Mas-Aguilar, A., Mazin, D., Menchiari, S., Mender, S., Mićanović, S., Miceli, D., Miener, T., Miranda, J. M., Mirzoyan, R., Molina, E., Mondal, H. A., Moralejo, A., Morcuende, D., Moreno, V., Nakamori, T., Nanci, C., Nava, L., Neustroev, V., Nievas Rosillo, M., Nigro, C., Nilsson, K., Nishijima, K., Njoh Ekoume, T., Noda, K., Nozaki, S., Ohtani, Y., Oka, T., Okumura, A., Otero-Santos, J., Paiano, S., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J. M., Pavletić, L., Persic, M., Pihet, M., Pirola, G., Podobnik, F., Prada Moroni, P. G., Prandini, E., Principe, G., Priyadarshi, C., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Sahakyan, N., Saito, T., Sakurai, S., Satalecka, K., Saturni, F. G., Schleicher, B., Schmidt, K., Schmuckermaier, F., Schubert, J. L., Schweizer, T., Sitarek, J., Sliusar, V., Sobczynska, D., Spolon, A., Stamerra, A., Strišković, J., Strom, D., Strzys, M., Suda, Y., Surić, T., Tajima, H., Takahashi, M., Takeishi, R., Tavecchio, F., Temnikov, P., Terauchi, K., Terzić, T., Teshima, M., Tosti, L., Truzzi, S., Tutone, A., Ubach, S., van Scherpenberg, J., Vazquez Acosta, M., Ventura, S., Verguilov, V., Viale, I., Vigorito, C. F., Vitale, V., Vovk, I., Walter, R., Will, M., Wunderlich, C., Yamamoto, T., Zarić, D., Other, Groups, Cerruti, collaborations: M., Acosta-Pulido, J. A., Apolonio, G., Bachev, R., Baloković, M., Benítez, E., Björklund, I., Bozhilov, V., Brown, L. F., Bugg, A., Carbonell, W., Carnerero, M. I., Carosati, D., Casadio, C., Chamani, W., Chen, W. P., Chigladze, R. A., Damljanovic, G., Epps, K., Erkenov, A., Feige, M., Finke, J., Fuentes, A., Gazeas, K., Giroletti, M., Grishina, T. S., Gupta, A. C., Gurwell, M. A., Heidemann, E., Hiriart, D., Hou, W. J., Hovatta, T., Ibryamov, S., Joner, M. D., Jorstad, S. G., Kania, J., Kiehlmann, S., Kimeridze, G. N., Kopatskaya, E. N., Kopp, M., Korte, M., Kotas, B., Koyama, S., Kramer, J. A., Kunkel, L., Kurtanidze, S. O., Kurtanidze, O. M., Lähteenmäki, A., López, J. M., Larionov, V. M., Larionova, E. G., Larionova, L. V., Leto, C., Lorey, C., Mújica, R., Madejski, G. M., Marchili, N., Marscher, A. P., Minev, M., Modaressi, A., Morozova, D. A., Mufakharov, T., Myserlis, I., Nikiforova, A. A., Nikolashvili, M. G., Ovcharov, E., Perri, M., Raiteri, C. M., Readhead, A. C. S., Reimer, A., Reinhart, D., Righini, S., Rosenlehner, K., Sadun, A. C., Savchenko, S. S., Scherbantin, A., Schneider, L., Schoch, K., Seifert, D., Semkov, E., Sigua, L. A., Singh, C., Sola, P., Sotnikova, Y., Spencer, M., Steineke, R., Stojanovic, M., Strigachev, A., Tornikoski, M., Traianou, E., Tramacere, A., Troitskaya, Yu. V., Troitskiy, I. S., Trump, J. B., Tsai, A., Valcheva, A., Vasilyev, A. A., Verrecchia, F., Villata, M., Vince, O., Vrontaki, K., Weaver, Z. R., Zaharieva, E., Zottmann, N., Ministerio de Ciencia e Innovación (España), European Commission, Federal Ministry of Education and Research (Germany), Istituto Nazionale di Fisica Nucleare, Istituto Nazionale di Astrofisica, Swiss National Science Foundation, Department of Atomic Energy (India), Ministry of Education, Culture, Sports, Science and Technology (Japan), Ministry of Education and Science (Bulgaria), and Academy of Finland
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High Energy Astrophysical Phenomena (astro-ph.HE) ,BL Lacertae objects: individual (VER J0521+211 = RGB J0521.8+2112) – galaxies: active – galaxies: jets – gamma rays: galaxies – radiation mechanisms: non-thermal ,Astrophysics::High Energy Astrophysical Phenomena ,FOS: Physical sciences ,Astronomy and Astrophysics ,Active galactic nuclei ,High energy astrophysics ,Blazars ,BL Lacertae objects ,Relativistic jets ,Gamma-rays ,Non-thermal radiation sources ,Astrophysics::Cosmology and Extragalactic Astrophysics ,Astrophysics - Astrophysics of Galaxies ,Space and Planetary Science ,Astrophysics of Galaxies (astro-ph.GA) ,ddc:520 ,Física nuclear ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
Full list of authors: Adams, C. B.; Batista, P.; Benbow, W.; Brill, A.; Brose, R.; Buckley, J. H.; Capasso, M.; Christiansen, J. L.; Errando, M.; Feng, Q.; Finley, J. P.; Foote, G. M.; Fortson, L.; Furniss, A.; Gallagher, G.; Gent, A.; Giuri, C.; Hanlon, W. F.; Hanna, D.; Hassan, T.; Hervet, O.; Holder, J.; Hona, B.; Hughes, G.; Humensky, T. B.; Jin, W.; Kaaret, P.; Kertzman, M.; Kieda, D.; Kleiner, T. K.; Krennrich, F.; Kumar, S.; Lang, M. J.; Lundy, M.; Maier, G.; Millis, J.; Moriarty, P.; Mukherjee, R.; Nievas-Rosillo, M.; Ong, R. A.; Otte, A. N.; Patel, S.; Patel, S. R.; Pfrang, K.; Pohl, M.; Prado, R. R.; Pueschel, E.; Quinn, J.; Ragan, K.; Reynolds, P. T.; Ribeiro, D.; Roache, E.; Ryan, J. L.; Sadeh, I; Santander, M.; Sembroski, G. H.; Shang, R.; Stevenson, B.; Tucci, J., V; Vassiliev, V. V.; Wakely, S. P.; Weinstein, A.; Wells, R. M.; Williams, D. A.; Williamson, T. J.; Acciari, V. A.; Aniello, T.; Ansoldi, S.; Antonelli, L. A.; Engels, A. Arbet; Arcaro, C.; Artero, M.; Asano, K.; Baack, D.; Babic, A.; Baquero, A.; de Almeida, U. Barres; Barrio, J. A.; Batkovic, I; Becerra Gonzalez, J.; Bednarek, W.; Bernardini, E.; Bernardos, M.; Berti, A.; Besenrieder, J.; Bhattacharyya, W.; Bigongiari, C.; Biland, A.; Blanch, O.; Bokenkamp, H.; Bonnoli, G.; Bosnjak, Z.; Burelli, I; Busetto, G.; Carosi, R.; Ceribella, G.; Cerruti, M.; Chai, Y.; Chilingarian, A.; Cikota, S.; Colombo, E.; Contreras, J. L.; Cortina, J.; Covino, S.; D'Amico, G.; D'Elia, V; Da Vela, P.; Dazzi, F.; De Angelis, A.; De Lotto, B.; Del Popolo, A.; Delfino, M.; Delgado, J.; Delgado Mendez, C.; Depaoli, D.; Di Pierro, F.; Di Venere, L.; Do Souto Espineira, E.; Prester, D. Dominis; Donini, A.; Dorner, D.; Doro, M.; Elsaesser, D.; Ramazani, V. Fallah; Farina, L.; Fattorini, A.; Font, L.; Fruck, C.; Fukami, S.; Fukazawa, Y.; Garcia Lopez, R. J.; Garczarczyk, M.; Gasparyan, S.; Gaug, M.; Giglietto, N.; Giordano, F.; Gliwny, P.; Godinovic, N.; Green, J. G.; Green, D.; Hadasch, D.; Hahn, A.; Hassan, T.; Heckmann, L.; Herrera, J.; Hrupec, D.; Hutten, M.; Inada, T.; Iotov, R.; Ishio, K.; Iwamura, Y.; Jimenez Martinez, I; Jormanainen, J.; Jouvin, L.; Kerszberg, D.; Kobayashi, Y.; Kubo, H.; Kushida, J.; Lamastra, A.; Lelas, D.; Leone, F.; Lindfors, E.; Linhoff, L.; Lombardi, S.; Longo, F.; Lopez-Coto, R.; Lopez-Moya, M.; Lopez-Oramas, A.; Loporchio, S.; Lorini, A.; de Oliveira Fraga, B. Machado; Maggio, C.; Majumdar, P.; Makariev, M.; Maneva, G.; Manganaro, M.; Mannheim, K.; Mariotti, M.; Martinez, M.; Aguilar, A. Mas; Mazin, D.; Menchiari, S.; Mender, S.; Micanovic, S.; Miceli, D.; Miener, T.; Miranda, J. M.; Mirzoyan, R.; Molina, E.; Mondal, H. A.; Moralejo, A.; Morcuende, D.; Moreno, V; Nakamori, T.; Nanci, C.; Nava, L.; Neustroev, V; Nievas Rosillo, M.; Nigro, C.; Nilsson, K.; Nishijima, K.; Noda, K.; Nozaki, S.; Ohtani, Y.; Oka, T.; Otero-Santos, J.; Paiano, S.; Palatiello, M.; Paneque, D.; Paoletti, R.; Paredes, J. M.; Pavletic, L.; Penil, P.; Persic, M.; Pihet, M.; Moroni, P. G. Prada; Prandini, E.; Priyadarshi, C.; Puljak, I; Rhode, W.; Ribo, M.; Rico, J.; Righi, C.; Rugliancich, A.; Sahakyan, N.; Saito, T.; Sakurai, S.; Satalecka, K.; Saturni, F. G.; Schleicher, B.; Schmidt, K.; Schmuckermaier, F.; Schubert, J. L.; Schweizer, T.; Sitarek, J.; Snidaric, I; Sobczynska, D.; Spolon, A.; Stamerra, A.; Striskovic, J.; Strom, D.; Strzys, M.; Suda, Y.; Suric, T.; Takahashi, M.; Takeishi, R.; Tavecchio, F.; Temnikov, P.; Terzic, T.; Teshima, M.; Tosti, L.; Truzzi, S.; Tutone, A.; Ubach, S.; van Scherpenberg, J.; Vanzo, G.; Vazquez Acosta, M.; Ventura, S.; Verguilov, V.; Viale, I; Vigorito, C. F.; Vitale, V.; Vovk, I; Will, M.; Wunderlich, C.; Yamamoto, T.; Zaric, D.; VERITAS Collaboration; MAGIC Collaboration.--This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited., We report on a long-lasting, elevated gamma-ray flux state from VER J0521+211 observed by VERITAS, MAGIC, and Fermi-LAT in 2013 and 2014. The peak integral flux above 200 GeV measured with the nightly binned light curve is (8.8 ± 0.4) × 10−7 photons m−2 s−1, or ∼37% of the Crab Nebula flux. Multiwavelength observations from X-ray, UV, and optical instruments are also presented. A moderate correlation between the X-ray and TeV gamma-ray fluxes was observed, and the X-ray spectrum appeared harder when the flux was higher. Using the gamma-ray spectrum and four models of the extragalactic background light (EBL), a conservative 95% confidence upper limit on the redshift of the source was found to be z ≤ 0.31. Unlike the gamma-ray and X-ray bands, the optical flux did not increase significantly during the studied period compared to the archival low-state flux. The spectral variability from optical to X-ray bands suggests that the synchrotron peak of the spectral energy distribution (SED) may become broader during flaring states, which can be adequately described with a one-zone synchrotron self-Compton model varying the high-energy end of the underlying particle spectrum. The synchrotron peak frequency of the SED and the radio morphology of the jet from the MOJAVE program are consistent with the source being an intermediate-frequency-peaked BL Lac object. © 2022. The Author(s). Published by the American Astronomical Society., This research is supported by grants from the U.S. Department of Energy Office of Science, the U.S. National Science Foundation, and the Smithsonian Institution in the U.S.; by NSERC in Canada; and by the Helmholtz Association in Germany. This research used resources provided by the Open Science Grid, which is supported by the National Science Foundation and the U.S. Department of Energy's Office of Science, and resources of the National Energy Research Scientific Computing Center (NERSC), a U.S. Department of Energy Office of Science User Facility operated under contract No. DE-AC02-05CH11231. We acknowledge the excellent work of the technical support staff at the Fred Lawrence Whipple Observatory and at the collaborating institutions in the construction and operation of the instrument. The MAGIC Collaboration would like to thank the Instituto de Astrofísica de Canarias for the excellent working conditions at the Observatorio del Roque de los Muchachos in La Palma. The financial support of the German BMBF, MPG, and HGF; the Italian INFN and INAF; the Swiss National Fund SNF; the ERDF under the Spanish Ministerio de Ciencia e Innovación (MICINN) (PID2019-104114RB-C31, PID2019-104114RB-C32, PID2019-104114RB-C33, PID2019-105510GB-C31,PID2019-107847RB-C41, PID2019-107847RB-C42, PID2019-107847RB-C44, PID2019-107988GB-C22); the Indian Department of Atomic Energy; the Japanese ICRR, the University of Tokyo, JSPS, and MEXT; the Bulgarian Ministry of Education and Science, National RI Roadmap Project DO1-400/18.12.2020; and the Academy of Finland grant No. 320045 is gratefully acknowledged. This work was also supported by the Spanish Centro de Excelencia "Severo Ochoa" (SEV-2016-0588, SEV-2017-0709, CEX2019-000920-S), the Unidad de Excelencia "María de Maeztu" (CEX2019-000918-M, MDM-2015-0509-18-2), and the CERCA program of the Generalitat de Catalunya; by the Croatian Science Foundation (HrZZ) Project IP-2016-06-9782 and the University of Rijeka Project uniri-prirod-18-48; by the DFG Collaborative Research Centers SFB823/C4 and SFB876/C3; by the Polish National Research Centre grant UMO-2016/22/M/ST9/00382; and by the Brazilian MCTIC, CNPq, and FAPERJ. Q.F. was supported by NSF grant PHY-1806554 at Barnard College.
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- 2022
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15. Unveiling the complex correlation patterns in Mrk 421
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Arbet-Engels, A., Paneque, D., Heckmann, L., Acciari, V. A., Ansoldi, S., Antonelli, L. A., Artero, M., Asano, K., Baack, D., Babić, A., Baquero, A., Barres Almeida, U., Barrio, J. A., Batković, I., Becerra González, J., Bednarek, W., Bellizzi, L., Bernardini, E., Bernardos, M., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bökenkamp, H., Bonnoli, G., Bošnjak, Ž, Busetto, G., Carosi, R., Ceribella, G., Cerruti, M., Chai, Y., Chilingarian, A., Cikota, S., Colak, S. M., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., Giacomo D'Amico, D Elia, V., Da Vela, P., Dazzi, F., Angelis, A., Lotto, B., Delfino, M., Delgado, J., Delgado Mendez, C., Depaoli, D., Di Pierro, F., Di Venere, L., Do Souto Espiñeira, E., Dominis Prester, D., Donini, A., Dorner, D., Doro, M., Elsaesser, D., Fallah Ramazani, V., Fattorini, A., Fonseca, M. V., Font, L., Fruck, C., Fukami, S., Fukazawa, Y., García López, R. J., Garczarczyk, M., Gasparyan, S., Gaug, M., Giglietto, N., Giordano, F., Gliwny, P., Godinović, N., Green, J. G., Green, D., Hadasch, D., Hahn, A., Herrera, J., Hoang, J., Hrupec, D., Hütten, M., Inada, T., Ishio, K., Iwamura, Y., Jiménez Martínez, I., Jormanainen, J., Jouvin, L., Karjalainen, M., Kerszberg, D., Kobayashi, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Linhoff, L., Lombardi, S., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Machado Oliveira Fraga, B., Maggio, C., Majumdar, P., Makariev, M., Mallamaci, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Menchiari, S., Mender, S., Mićanović, S., Miceli, D., Miener, T., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Morcuende, D., Moreno, V., Moretti, E., Nakamori, T., Nava, L., Neustroev, V., Nigro, C., Nilsson, K., Nishijima, K., Noda, K., Nozaki, S., Ohtani, Y., Oka, T., Otero-Santos, J., Paiano, S., Palatiello, M., Paoletti, R., Paredes, J. M., Pavletić, L., Peñil, P., Persic, M., Pihet, M., Prada Moroni, P. G., Prandini, E., Priyadarshi, C., Puljak, I., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Sahakyan, N., Saito, T., Sakurai, S., Satalecka, K., Saturni, F. G., Schleicher, B., Schmidt, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Spolon, A., Stamerra, A., Strišković, J., Strom, D., Strzys, M., Suda, Y., Surić, T., Takahashi, M., Takeishi, R., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Tosti, L., Truzzi, S., Tutone, A., Ubach, S., Scherpenberg, J., Vanzo, G., Vazquez Acosta, M., Ventura, S., Verguilov, V., Vigorito, C. F., Vitale, V., Vovk, I., Will, M., Wunderlich, C., Yamamoto, T., Zarić, D., Balbo, M., Bretz, T., Buss, J., Eisenberger, L., Hildebrand, D., Iotov, R., Kalenski, A., D Ammando, F., Horan, D., Lien, A. Y., Baloković, M., Madejski, G. M., Perri, M., Verrecchia, F., Leto, C., Lähteenmäki, A., Tornikoski, M., Ramakrishnan, V., Järvelä, E., Vera, R. J. C., Villata, M., Raiteri, C. M., Gupta, A. C., Pandey, A., Fuentes, A., Agudo, I., Casadio, C., Semkov, E., Ibryamov, S., Marchini, A., Bachev, R., Strigachev, A., Ovcharov, E., Bozhilov, V., Valcheva, A., Zaharieva, E., Damljanovic, G., Vince, O., Larionov, V. M., Borman, G. A., Grishina, T. S., Hagen-Thorn, V. A., Kopatskaya, E. N., Larionova, E. G., Larionova, L. V., Morozova, D. A., Nikiforova, A. A., Savchenko, S. S., Troitskiy, I. S., Troitskaya, Y. V., Vasilyev, A. A., Merkulova, O. A., Chen, W. P., Samal, M., Lin, H. C., Moody, J. W., Sadun, A. C., Jorstad, S. G., Marscher, A. P., Weaver, Z. R., Feige, M., Kania, J., Kopp, M., Kunkel, L., Reinhart, D., Scherbantin, A., Schneider, L., Lorey, C., Acosta-Pulido, J. A., Carnerero, M. I., Carosati, D., Kurtanidze, S. O., Kurtanidze, O. M., Nikolashvili, M. G., Chanishvili, R. G., Chigladze, R. A., Ivanidze, R. Z., Kimeridze, G. N., Sigua, L. A., Joner, M. D., Spencer, M., Giroletti, M., Marchili, N., Righini, S., and Rizzi, N.
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Physics ,education.field_of_study ,Astrophysics::High Energy Astrophysical Phenomena ,Population ,Flux ,Sigma ,Astrophysics ,Synchrotron ,Redshift ,law.invention ,law ,MAGIC (telescope) ,education ,Blazar ,Flare - Abstract
The blazar Mrk421 (redshift z=0.031) is one of the brightest and closest BL Lac type objects, making it an ideal target to probe blazar physics. We report on an extensive multi-wavelength observing campaign in 2017, during which the intra-band correlation patterns show some disparity and complex behaviours. Observations from several instruments are used to achieve an optimal temporal coverage from radio to TeV energies. In particular, four multi-hour NuSTAR observations organised simultaneously with MAGIC allow to obtain a precise measurement of the falling segments of the two spectral components. A detailed investigation of the very-high-energy (VHE; >100 GeV) versus X-ray flux correlation is performed, by binning the data into several sub-energy bands. A positively correlated variability is observed, but the correlation characteristics change substantially across the various bands probed. Furthermore, during the simultaneous MAGIC and NuSTAR observations a clear change of the Compton dominance is detected without a simultaneous change in the synchrotron regime, indicating "orphan gamma-ray activity". We also investigate an intriguing bright flare at VHE without a substantial flux increase in the X-rays. Within a leptonic scenario, this behaviour is best explained by the appearance of a second population of highly-energetic electrons spanning a narrow range of energies. Finally, our multi-wavelength correlation study also reveals an anti-correlation between the UV/optical and X-ray bands at a significance level above 3 sigma.
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- 2022
16. Primary Hyperparathyroidism – A Contemporary Picture Based on 100 Patients from the Last Decade
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Boyanov, M., primary, Bakalov, D., additional, Karamfilova, V., additional, Gateva, A., additional, Assyov, Y., additional, Zaharieva, E., additional, Atanassova, K., additional, Sheinkova, G., additional, Tsakova, A., additional, and Kamenov, Z., additional
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- 2021
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17. The complex variability of blazars: time-scales and periodicity analysis in S4 0954+65
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Raiteri, C M, primary, Villata, M, additional, Larionov, V M, additional, Jorstad, S G, additional, Marscher, A P, additional, Weaver, Z R, additional, Acosta-Pulido, J A, additional, Agudo, I, additional, Andreeva, T, additional, Arkharov, A, additional, Bachev, R, additional, Benítez, E, additional, Berton, M, additional, Björklund, I, additional, Borman, G A, additional, Bozhilov, V, additional, Carnerero, M I, additional, Carosati, D, additional, Casadio, C, additional, Chen, W P, additional, Damljanovic, G, additional, D’Ammando, F, additional, Escudero, J, additional, Fuentes, A, additional, Giroletti, M, additional, Grishina, T S, additional, Gupta, A C, additional, Hagen-Thorn, V A, additional, Hart, M, additional, Hiriart, D, additional, Hou, W-J, additional, Ivanov, D, additional, Kim, J-Y, additional, Kimeridze, G N, additional, Konstantopoulou, C, additional, Kopatskaya, E N, additional, Kurtanidze, O M, additional, Kurtanidze, S O, additional, Lähteenmäki, A, additional, Larionova, E G, additional, Larionova, L V, additional, Marchili, N, additional, Markovic, G, additional, Minev, M, additional, Morozova, D A, additional, Myserlis, I, additional, Nakamura, M, additional, Nikiforova, A A, additional, Nikolashvili, M G, additional, Otero-Santos, J, additional, Ovcharov, E, additional, Pursimo, T, additional, Rahimov, I, additional, Righini, S, additional, Sakamoto, T, additional, Savchenko, S S, additional, Semkov, E H, additional, Shakhovskoy, D, additional, Sigua, L A, additional, Stojanovic, M, additional, Strigachev, A, additional, Thum, C, additional, Tornikoski, M, additional, Traianou, E, additional, Troitskaya, Y V, additional, Troitskiy, I S, additional, Tsai, A, additional, Valcheva, A, additional, Vasilyev, A A, additional, Vince, O, additional, and Zaharieva, E, additional
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- 2021
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18. Multiwavelength Variability of BL Lacertae Measured with High Time Resolution
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Weaver, Z. R., primary, Williamson, K. E., additional, Jorstad, S. G., additional, Marscher, A. P., additional, Larionov, V. M., additional, Raiteri, C. M., additional, Villata, M., additional, Acosta-Pulido, J. A., additional, Bachev, R., additional, Baida, G. V, additional, Balonek, T. J., additional, Benítez, E., additional, Borman, G. A., additional, Bozhilov, V., additional, Carnerero, M. I., additional, Carosati, D., additional, Chen, W. P., additional, Damljanovic, G., additional, Dhiman, V., additional, Dougherty, D. J., additional, Ehgamberdiev, S. A., additional, Grishina, T. S., additional, Gupta, A. C., additional, Hart, M., additional, Hiriart, D., additional, Hsiao, H. Y., additional, Ibryamov, S., additional, Joner, M., additional, Kimeridze, G. N., additional, Kopatskaya, E. N., additional, Kurtanidze, O. M., additional, Kurtanidze, S. O., additional, Larionova, E. G., additional, Matsumoto, K., additional, Matsumura, R., additional, Minev, M., additional, Mirzaqulov, D. O., additional, Morozova, D. A., additional, Nikiforova, A. A., additional, Nikolashvili, M. G., additional, Ovcharov, E., additional, Rizzi, N., additional, Sadun, A., additional, Savchenko, S. S., additional, Semkov, E., additional, Slater, J. J., additional, Smith, K. L., additional, Stojanovic, M., additional, Strigachev, A., additional, Troitskaya, Yu. V., additional, Troitsky, I. S., additional, Tsai, A. L., additional, Vince, O., additional, Valcheva, A., additional, Vasilyev, A. A., additional, Zaharieva, E., additional, and Zhovtan, A. V., additional
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- 2020
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19. Multi-Wavelength Variability of BL Lacertae Measured with High Time Resolution
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Nikiforova, A. A., Vasilyev, A. A., Gupta, A. C., Tsai, A. L., Marscher, A. P., Sadun, A., Strigachev, A., Zhovtan, A. V., Valcheva, A., Raiteri, C. M., Morozova, D. A., Carosati, D., Hiriart, D., Dougherty, D. J., Mirzaqulov, D. O., Benitez, E., Larionova, E. G., Kopatskaya, E. N., Evgeni Ovcharov, Semkov, E., Zaharieva, E., Borman, G. A., Damljanovic, G., Kimeridze, G. N., Baida, G. V., Hsiao, H. Y., Troitsky, I. S., Acosta-Pulido, J. A., Slater, J. J., Williamson, K. E., Smith, K. L., Matsumoto, K., Nikolashvili, M. G., Hart, M., Carnerero, M. I., Joner, M., Minev, M., Stojanovic, M., Villata, M., Rizzi, N., Kurtanidze, O. M., Vince, O., Bachev, R., Matsumura, R., Ehgamberdiev, S. A., Jorstad, S. G., Ibryamov, S., Kurtanidze, S. O., Savchenko, S. S., Balonek, T. J., Grishina, T. S., Bozhilov, V., Dhiman, V., Larionov, V. M., Chen, W. P., Troitskaya, Yu V., and Weaver, Zachary R.
- Subjects
High Energy Astrophysical Phenomena (astro-ph.HE) ,Astrophysics::High Energy Astrophysical Phenomena ,Astrophysics of Galaxies (astro-ph.GA) ,FOS: Physical sciences ,Astrophysics::Earth and Planetary Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
In an effort to locate the sites of emission at different frequencies and physical processes causing variability in blazar jets, we have obtained high time-resolution observations of BL Lacertae over a wide wavelength range: with the \emph{Transiting Exoplanet Survey Satellite} (TESS) at 6,000-10,000 \AA\ with 2-minute cadence; with the Neil Gehrels \emph{Swift} satellite at optical, UV, and X-ray bands; with the Nuclear Spectroscopic Telescope Array at hard X-ray bands; with the \emph{Fermi} Large Area Telescope at $\gamma$-ray energies; and with the Whole Earth Blazar Telescope for measurement of the optical flux density and polarization. All light curves are correlated, with similar structure on timescales from hours to days. The shortest timescale of variability at optical frequencies observed with TESS is $\sim 0.5$ hr. The most common timescale is $13\pm1$~hr, comparable with the minimum timescale of X-ray variability, 14.5 hr. The multi-wavelength variability properties cannot be explained by a change solely in the Doppler factor of the emitting plasma. The polarization behavior implies that there are both ordered and turbulent components to the magnetic field in the jet. Correlation analysis indicates that the X-ray variations lag behind the $\gamma$-ray and optical light curves by up to $\sim 0.4$ days. The timescales of variability, cross-frequency lags, and polarization properties can be explained by turbulent plasma that is energized by a shock in the jet and subsequently loses energy to synchrotron and inverse Compton radiation in a magnetic field of strength $\sim3$ G, Comment: 33 pages, 25 figures, 14 tables. Accepted to ApJ
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- 2020
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20. Photometric Study of the Blazar OJ287.
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Zaharieva, E., Ovcharov, E., Minev, M., Bozhilov, V., and Valcheva, A.
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- *
BLACKBODY radiation , *ACCRETION disks - Abstract
We present the results from observations of the blazar OJ 287 in the B, V, R and I bands during December 2015 - February 2020. The obtained light curve of OJ 287 showed long-term timescale variability with a large amplitude. We found untypical variations in the color indexes (B-V) and (V-R) in short-term period. A dominating black body radiation from the accretion disc and the Broad-Line Region (BLR) emission lines appearance in the blazar spectrum might be the probable reasons for these variations. [ABSTRACT FROM AUTHOR]
- Published
- 2021
21. Asymmetry of Limb Circumferences in Female Athletes
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Zaharieva, E., primary
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22. DNA damage and repair in white blood cells at occupational exposure
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Georgieva, R T, primary, Zaharieva, E K, additional, Rupova, I M, additional, Acheva, A R, additional, and Nikolov, V N, additional
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- 2008
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23. TLR4 polymorphisms seem not to be associated with prediabetes and type 2 diabetes but predispose to diabetic retinopathy; TLR4 polymorphisms in glucose continuum
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Zaharieva ET, Kamenov ZA, and Savov AS
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type 2 diabetes ,prediabetes ,diabetic complications ,toll-like receptor 4 ,single nucleotide polymorphism ,innate immune response ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
Objectives. Compared to type 1 diabetes, the role of the immune and autoimmune pathogenetic mechanisms is much less studied in the type 2 diabetes. Toll-like receptors 4 (TLR4) have a leading role in inflammation, insulin resistance, and vascular damage. This study aimed to analyze the relationship between the polymorphisms in TLR4 gene and different stages in the glucose continuum from prediabetes to the type 2 diabetes and chronic microvascular complications.
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- 2017
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24. Coated reactive carriers based on copolymers of 1-vinyl-2-pyrrolidone and maleic anhydride for immobilization of enzymes
- Author
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Zaharieva, E. I., Georgiev, G. G., and Konstantinov, C. I.
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- 1996
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25. Investigation of the correlation patterns and the Compton dominance variability of Mrk 421 in 2017
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Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Artero, M., Asano, K., Babi��, A., Baquero, A., de Almeida, U. Barres, Barrio, J. A., Batkovi��, I., Gonz��lez, J. Becerra, Bednarek, W., Bellizzi, L., Bernardini, E., Bernardos, M., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Blanch, O., Bo��njak, Z., Busetto, G., Carosi, R., Ceribella, G., Cerruti, M., Chai, Y., Chilingarian, A., Cikota, S., Colak, S. M., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D'Amico, G., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Mendez, C. Delgado, Depaoli, D., Di Pierro, F., Di Venere, L., Do Souto Espi��eira, E., Prester, D. Dominis, Donini, A., Doro, M., Ramazani, V. Fallah, Fattorini, A., Ferrara, G., Fonseca, M. V., Font, L., Fruck, C., Fukami, S., L��pez, R. J. Garc��a, Garczarczyk, Markus, Gasparyan, S., Gaug, M., Giglietto, N., Giordano, F., Gliwny, P., Godinovi��, N., Green, J. G., Green, D., Hadasch, D., Hahn, A., Heckmann, L., Herrera, J., Hoang, J., Hrupec, D., H��tten, M., Inada, T., Inoue, S., Ishio, K., Iwamura, Y., Jim��nez, I., Jormanainen, J., Jouvin, L., Kajiwara, Y., Karjalainen, M., Kerszberg, D., Kobayashi, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., L��pez-Coto, R., L��pez-Moya, M., L��pez-Oramas, A., Loporchio, S., de Oliveira Fraga, B. Machado, Maggio, C., Majumdar, P., Makariev, M., Mallamaci, M., Maneva, G., Manganaro, M., Maraschi, L., Mariotti, M., Mart��nez, M., Mazin, D., Menchiari, S., Mender, S., Mi��anovi��, S., Miceli, D., Miener, T., Minev, M., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Morcuende, D., Moreno, V., Moretti, E., Neustroev, V., Nigro, C., Nilsson, K., Nishijima, K., Noda, K., Nozaki, S., Ohtani, Y., Oka, T., Otero-Santos, J., Paiano, S., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J. M., Pavleti��, L., Pe��il, P., Perennes, C., Persic, M., Moroni, P. G. Prada, Prandini, E., Priyadarshi, C., Puljak, I., Rib��, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Sahakyan, N., Saito, T., Sakurai, S., Satalecka, K., Saturni, F. G., Schmidt, K., Schweizer, T., Sitarek, J., ��nidari��, I., Sobczynska, D., Spolon, A., Stamerra, A., Strom, D., Strzys, M., Suda, Y., Suri��, T., Takahashi, M., Tavecchio, F., Temnikov, P., Terzi��, T., Teshima, M., Tosti, L., Truzzi, S., Tutone, A., Ubach, S., van Scherpenberg, J., Vanzo, G., Acosta, M. Vazquez, Ventura, S., Verguilov, V., Vigorito, C. F., Vitale, V., Vovk, I., Will, M., Wunderlich, C., Zari��, D., Baack, D., Balbo, M., Biederbeck, N., Biland, A., Bretz, T., Buss, J., Dorner, D., Eisenberger, L., Elsaesser, D., Hildebrand, D., Iotov, R., Mannheim, K., Neise, D., Noethe, M., Paravac, A., Rhode, W., Schleicher, B., Sliusar, V., Walter, R., D'Ammando, F., Horan, D., Lien, A. Y., Balokovi��, M., Madejski, G. M., Perri, M., Verrecchia, F., Leto, C., L��hteenm��ki, A., Tornikoski, M., Ramakrishnan, V., J��rvel��, E., Vera, R. J. C., Chamani, W., Villata, M., Raiteri, C. M., Gupta, A. C., Pandey, A., Fuentes, A., Agudo, I., Casadio, C., Semkov, E., Ibryamov, S., Marchini, A., Bachev, R., Strigachev, A., Ovcharov, E., Bozhilov, V., Valcheva, A., Zaharieva, E., Damljanovic, G., Vince, O., Larionov, V. M., Borman, G. A., Grishina, T. S., Hagen-Thorn, V. A., Kopatskaya, E. N., Larionova, E. G., Larionova, L. V., Morozova, D. A., Nikiforova, A. A., Savchenko, S. S., Troitskiy, I. S., Troitskaya, Y. V., Vasilyev, A. A., Merkulova, O. A., Chen, W. P., Samal, M., Lin, H. C., Moody, J. W., Sadun, A. C., Jorstad, S. G., Marscher, A. P., Weaver, Z. R., Feige, M., Kania, J., Kopp, M., Kunkel, L., Reinhart, D., Scherbantin, A., Schneider, L., Lorey, C., Acosta-Pulido, J. A., Carnerero, M. I., Carosati, D., Kurtanidze, S. O., Kurtanidze, O. M., Nikolashvili, M. G., Chanishvili, R. G., Chigladze, R. A., Ivanidze, R. Z., Kimeridze, G. N., Sigua, L. A., Joner, M. D., Spencer, M., Giroletti, M., Marchili, N., Righini, S., Rizzi, N., and Bonnoli, G.
- Subjects
electron ,galaxies: active ,flux: correlation ,GeV ,radiation mechanisms: non-thermal ,7. Clean energy ,MAGIC ,GLAST ,blazar ,gamma ray: VHE ,ultraviolet ,optical ,spectral ,TeV ,BL Lacertae objects: individual: Mrk 421 ,X-ray: flux ,model: leptonic ,Lorentz - Abstract
Astronomy and astrophysics 655, A89 (2021). doi:10.1051/0004-6361/202141004, Aims. We present a detailed characterisation and theoretical interpretation of the broadband emission of the paradigmatic TeV blazar Mrk 421, with a special focus on the multi-band flux correlations.Methods. The dataset has been collected through an extensive multi-wavelength campaign organised between 2016 December and 2017 June. The instruments involved are MAGIC, FACT, Fermi-LAT, Swift, GASP-WEBT, OVRO, Medicina, and Mets��hovi. Additionally, four deep exposures (several hours long) with simultaneous MAGIC and NuSTAR observations allowed a precise measurement of the falling segments of the two spectral components.Results. The very-high-energy (VHE; E > 100 GeV) gamma rays and X-rays are positively correlated at zero time lag, but the strength and characteristics of the correlation change substantially across the various energy bands probed. The VHE versus X-ray fluxes follow different patterns, partly due to substantial changes in the Compton dominance for a few days without a simultaneous increase in the X-ray flux (i.e., orphan gamma-ray activity). Studying the broadband spectral energy distribution (SED) during the days including NuSTAR observations, we show that these changes can be explained within a one-zone leptonic model with a blob that increases its size over time. The peak frequency of the synchrotron bump varies by two orders of magnitude throughout the campaign. Our multi-band correlation study also hints at an anti-correlation between UV-optical and X-ray at a significance higher than 3��. A VHE flare observed on MJD 57788 (2017 February 4) shows gamma-ray variability on multi-hour timescales, with a factor ten increase in the TeV flux but only a moderate increase in the keV flux. The related broadband SED is better described by a two-zone leptonic scenario rather than by a one-zone scenario. We find that the flare can be produced by the appearance of a compact second blob populated by high energetic electrons spanning a narrow range of Lorentz factors, from �����$_{min}$=2��10$^4$ to �����$_{max}$=6��10$^5$.Key words: galaxies: active / BL Lacertae objects: individual: Mrk 421 / radiation mechanisms: non-thermal��� Light curves and spectral energy distributions data are only available at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/cat/J/A+A/655/A89������ Corresponding authors: A. Arbet Engels and D. Paneque; e-mail: contact.magic@mpp.mpg.de.��������� Also member of the MAGIC Collaboration.������������ Also member of the FACT Collaboration., Published by EDP Sciences, Les Ulis
26. Radiation can stimulate secretion of TNFα by human mononuclear cells treated with LPS
- Author
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Aneva, N., Zaharieva, E., Gergana Savova, Stankova, K., and Boteva, R.
27. Molecular markers for assessment of radiation-induced oxidative stress in occupationally exposed subjects
- Author
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Stankova, K., Zaharieva, E., Nevena Aneva, Katsarska, O., Savova, G., and Boteva, R.
28. Olympic participation by women. Effects on pregnancy and childbirth
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Zaharieva, E., primary
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- 1972
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29. Investigation of the correlation patterns and the Compton dominance variability of Mrk 421 in 2017
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Katsuaki Asano, I. Jiménez, A. Fuentes, C. M. Raiteri, D. Dominis Prester, E. Molina, E. Colombo, Y. V. Troitskaya, Nikola Godinovic, Sidika Merve Colak, Jenni Jormanainen, Yuki Iwamura, Alessandra Lamastra, Lab Saha, Antoniya Valcheva, Sunay Ibryamov, Elena G. Larionova, B. De Lotto, Evgeni Ovcharov, D. Zarić, Kazuma Ishio, David A. Green, M. Villata, D. Horan, Givi N. Kimeridze, Alexander Hahn, S. Nozaki, M. Perri, Michael D. Joner, D. Neise, S. Loporchio, R. J. García López, Marcello Giroletti, Victor A. Acciari, V. Fallah Ramazani, Tomohiko Oka, Daniela Dorner, Narek Sahakyan, J. Kushida, M. Kopp, Lorenzo Bellizzi, Noah Biederbeck, Joseph Moody, M. Gaug, L. Schneider, A. López-Oramas, Daniel Morcuende, N. Rizzi, Jose Luis Contreras, G. Vanzo, Rodolfo Carosi, L. Maraschi, Andrés Baquero, M. I. Carnerero, R. Iotov, Mosè Mariotti, A. Paravac, John Hoang, Ashwani Pandey, Z. R. Weaver, Francesco Longo, F. D'Ammando, S. Paiano, Elina Lindfors, Moritz Hütten, J. Herrera, Koji Noda, Abelardo Moralejo, Laura Eisenberger, E. Moretti, Julian Sitarek, Marcos López-Moya, Wlodek Bednarek, L. Di Venere, Ashot Chilingarian, U. Barres de Almeida, Elisa Bernardini, I. Agudo, M. Feige, R. Z. Ivanidze, O. A. Merkulova, D. Depaoli, M. Spencer, Massimo Persic, J. van Scherpenberg, Pratik Majumdar, L. Kunkel, K. Nishijima, Stefano Ansoldi, Juan Cortina, Kai Phillip Schmidt, A. Berti, Riccardo Paoletti, Saverio Lombardi, Daniel Mazin, M. V. Fonseca, Damir Lelas, R. J. C. Vera, Sanae Inoue, Giacomo D'Amico, Dominik Baack, C. Perennes, A. A. Nikiforova, Yating Chai, Stefan Cikota, G. M. Madejski, A. Arbet Engels, Daniel Kerszberg, Manuel Artero, E. Do Souto Espiñeira, Tomislav Terzić, J. Becerra González, Martin Makariev, R. Mirzoyan, Yoshiki Ohtani, G. A. Borman, Pawel Gliwny, Jose Miguel Miranda, A. De Angelis, Vitaly Neustroev, Wara Chamani, Oscar Blanch, T. S. Grishina, Martin Will, M. Vazquez Acosta, Nicola Giglietto, L. V. Larionova, Lea Heckmann, Francesco Gabriele Saturni, Jorge Otero-Santos, R. A. Chigladze, M. Balbo, N. Marchili, D. Hadasch, P. G. Prada Moroni, A. A. Vasilyev, M. G. Nikolashvili, Jordi Delgado, V. Ramakrishnan, Christian Fruck, G. Busetto, Victoria Moreno, Luca Tosti, A. Rugliancich, C. Nigro, Marina Manganaro, Valeri M. Larionov, M. Balokovic, Manuel Delfino, A. Strigachev, J. M. Paredes, Manash R. Samal, Stefano Covino, I. Vovk, H. C. Lin, Ž. Bošnjak, Stefano Menchiari, Rumen Bachev, Marc Ribó, Dorota Sobczyńska, Carolin Wunderlich, Bernd Schleicher, M. Minev, Antonio Stamerra, Maria-Isabel Bernardos, I. S. Troitskiy, Merja Tornikoski, E. N. Kopatskaya, Shunsuke Sakurai, Camilla Maggio, Chiara Righi, F. Verrecchia, P. Temnikov, S. G. Jorstad, T. Schweizer, Hidetoshi Kubo, Lluis Font, A. Y. Lien, Toshiaki Inada, A. Scherbantin, Lorand A. Sigua, G. Maneva, Stefano Truzzi, B. Machado de Oliveira Fraga, V. Bozhilov, M. Palatiello, Alessandro Marchini, Chaitanya Priyadarshi, Alessia Spolon, Léa Jouvin, Konstancja Satalecka, Tomoki Saito, Giovanni Ceribella, Michele Doro, S. O. Kurtanidze, Carlo Vigorito, Pablo Peñil, D. Strom, Giacomo Bonnoli, Adrian Biland, Ana Babić, Alicia Fattorini, D. Hildebrand, Satoshi Fukami, G. Ferrara, Y. Kajiwara, Matteo Cerruti, P. Da Vela, Vassil Verguilov, Lovro Pavletić, C. Delgado Mendez, Emilia Järvelä, S. Mićanović, Sergey S. Savchenko, Ivica Puljak, M. Noethe, Simone Mender, Francesco Dazzi, V. Vitale, Manuela Mallamaci, Ivana Batković, F. Leone, M. I. Martínez, J. Rico, Alan P. Marscher, C. Lorey, S. Ventura, Tjark Miener, Anne Lähteenmäki, David Paneque, Masahiro Teshima, Jarred Gershon Green, Wrijupan Bhattacharyya, Kari Nilsson, R. Walter, M. Strzys, D. Reinhart, E. Zaharieva, Wen Ping Chen, Vitalii Sliusar, Jürgen Besenrieder, Francesco Giordano, Antonio Tutone, Thomas Bretz, J. Buss, Alok C. Gupta, Simona Righini, O. M. Kurtanidze, Ciro Bigongiari, O. Vince, D. Elsaesser, C. Leto, M. Garczarczyk, Sargis Gasparyan, J. Kania, Dario Hrupec, R. López-Coto, Wolfgang Rhode, I. Snidaric, D. A. Morozova, Vladimir A. Hagen-Thorn, Mitsunari Takahashi, J. A. Acosta-Pulido, E. Prandini, Marie Karjalainen, D. Miceli, Goran Damljanović, Evgeni Semkov, Alice Donini, L. A. Antonelli, J. A. Barrio, Y. Suda, D. Carosati, V. D'Elia, Fabrizio Tavecchio, A. C. Sadun, Tihomir Surić, C. Casadio, Karl Mannheim, Santiago Ubach, Y. Kobayashi, F. Di Pierro, European Commission, European Research Council, Ministerio de Ciencia e Innovación (España), Generalitat de Catalunya, Federal Ministry of Education and Research (Germany), German Research Foundation, Swiss National Science Foundation, Croatian Science Foundation, Ministry of Education, Science and Technological Development (Serbia), Bulgarian National Science Fund, National Aeronautics and Space Administration (US), Acciari, V. A., Ansoldi, S., Antonelli, L. A., Arbet Engels, A., Artero, M., Asano, K., Babi??, A., Baquero, A., Barres de Almeida, U., Barrio, J. A., Batkovi??, I., Becerra Gonz??lez, J., Bednarek, W., Bellizzi, L., Bernardini, E., Bernardos, M., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Blanch, O., Bo??njak, ??., Busetto, G., Carosi, R., Ceribella, G., Cerruti, M., Chai, Y., Chilingarian, A., Cikota, S., Colak, S. M., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D???amico, G., D???elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Delgado Mendez, C., Depaoli, D., Di Pierro, F., Di Venere, L., Do Souto Espi??eira, E., Dominis Prester, D., Donini, A., Doro, M., Fallah Ramazani, V., Fattorini, A., Ferrara, G., Fonseca, M. V., Font, L., Fruck, C., Fukami, S., Garc??a L??pez, R. J., Garczarczyk, M., Gasparyan, S., Gaug, M., Giglietto, N., Giordano, F., Gliwny, P., Godinovi??, N., Green, J. G., Green, D., Hadasch, D., Hahn, A., Heckmann, L., Herrera, J., Hoang, J., Hrupec, D., H??tten, M., Inada, T., Inoue, S., Ishio, K., Iwamura, Y., Jim??nez, I., Jormanainen, J., Jouvin, L., Kajiwara, Y., Karjalainen, M., Kerszberg, D., Kobayashi, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., L??pez-Coto, R., L??pez-Moya, M., L??pez-Oramas, A., Loporchio, S., Machado de Oliveira Fraga, B., Maggio, C., Majumdar, P., Makariev, M., Mallamaci, M., Maneva, G., Manganaro, M., Maraschi, L., Mariotti, M., Mart??nez, M., Mazin, D., Menchiari, S., Mender, S., Mi??anovi??, S., Miceli, D., Miener, T., Minev, M., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Morcuende, D., Moreno, V., Moretti, E., Neustroev, V., Nigro, C., Nilsson, K., Nishijima, K., Noda, K., Nozaki, S., Ohtani, Y., Oka, T., Otero-Santos, J., Paiano, S., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J. M., Pavleti??, L., Pe??il, P., Perennes, C., Persic, M., Prada Moroni, P. G., Prandini, E., Priyadarshi, C., Puljak, I., Rib??, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Sahakyan, N., Saito, T., Sakurai, S., Satalecka, K., Saturni, F. G., Schmidt, K., Schweizer, T., Sitarek, J., nidari??, I., Sobczynska, D., Spolon, A., Stamerra, A., Strom, D., Strzys, M., Suda, Y., Suri??, T., Takahashi, M., Tavecchio, F., Temnikov, P., Terzi??, T., Teshima, M., Tosti, L., Truzzi, S., Tutone, A., Ubach, S., van Scherpenberg, J., Vanzo, G., Vazquez Acosta, M., Ventura, S., Verguilov, V., Vigorito, C. F., Vitale, V., Vovk, I., Will, M., Wunderlich, C., Zari??, D., Baack, D., Balbo, M., Biederbeck, N., Biland, A., Bretz, T., Buss, J., Dorner, D., Eisenberger, L., Elsaesser, D., Hildebrand, D., Iotov, R., Mannheim, K., Neise, D., Noethe, M., Paravac, A., Rhode, W., Schleicher, B., Sliusar, V., Walter, R., D???ammando, F., Horan, D., Lien, A. Y., Balokovi??, M., Madejski, G. M., Perri, M., Verrecchia, F., Leto, C., L??hteenm??ki, A., Tornikoski, M., Ramakrishnan, V., J??rvel??, E., Vera, R. J. C., Chamani, W., Villata, M., Raiteri, C. M., Gupta, A. C., Pandey, A., Fuentes, A., Agudo, I., Casadio, C., Semkov, E., Ibryamov, S., Marchini, A., Bachev, R., Strigachev, A., Ovcharov, E., Bozhilov, V., Valcheva, A., Zaharieva, E., Damljanovic, G., Vince, O., Larionov, V. M., Borman, G. A., Grishina, T. S., Hagen-Thorn, V. A., Kopatskaya, E. N., Larionova, E. G., Larionova, L. V., Morozova, D. A., Nikiforova, A. A., Savchenko, S. S., Troitskiy, I. S., Troitskaya, Y. V., Vasilyev, A. A., Merkulova, O. A., Chen, W. P., Samal, M., Lin, H. C., Moody, J. W., Sadun, A. C., Jorstad, S. G., Marscher, A. P., Weaver, Z. R., Feige, M., Kania, J., Kopp, M., Kunkel, L., Reinhart, D., Scherbantin, A., Schneider, L., Lorey, C., Acosta-Pulido, J. A., Carnerero, M. I., Carosati, D., Kurtanidze, S. O., Kurtanidze, O. M., Nikolashvili, M. G., Chigladze, R. A., Ivanidze, R. Z., Kimeridze, G. N., Sigua, L. A., Joner, M. D., Spencer, M., Giroletti, M., Marchili, N., Righini, S., Rizzi, N., Bonnoli, G., Laboratoire Leprince-Ringuet (LLR), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), MAGIC, FACT, Department of Electronics and Nanoengineering, Aalto-yliopisto, and Aalto University
- Subjects
electron ,PARTICLE-ACCELERATION ,ELECTRON ACCELERATION ,Radiation mechanisms: non-thermal ,RAY ,VHE [gamma ray] ,galaxies: active ,BL Lacertae objects: individual: Mrk 421 ,radiation mechanisms: non-thermal ,Electron ,Astrophysics ,GeV ,01 natural sciences ,7. Clean energy ,LARGE-AREA TELESCOPE ,law.invention ,OBSERVATIONS ,law ,ultraviolet ,optical ,MAGIC (telescope) ,correlation [flux] ,010303 astronomy & astrophysics ,X-ray: flux ,model: leptonic ,Physics ,High Energy Astrophysical Phenomena (astro-ph.HE) ,BL-LACERTAE ,individual: Mrk 421 [BL Lacertae objects] ,flux [X-ray] ,Gamma ray ,flux: correlation ,Galaxies: active ,non-thermal [radiation mechanisms] ,Synchrotron ,SWIFT OBSERVATIONS ,active [galaxies] ,Spectral energy distribution ,Física nuclear ,Astrophysics - High Energy Astrophysical Phenomena ,Lorentz ,Flare ,LOG-PARABOLIC SPECTRA ,ACTIVE GALACTIC NUCLEI ,Astrophysics::High Energy Astrophysical Phenomena ,FOS: Physical sciences ,radiation ,mechanisms: non-thermal ,LIGHT CURVES ,X-RAY ,MULTIWAVELENGTH ,GLAST ,leptonic [model] ,blazar ,0103 physical sciences ,TeV ,Blazar ,010308 nuclear & particles physics ,Astronomy and Astrophysics ,MAGIC ,gamma ray: VHE ,Space and Planetary Science ,ddc:520 ,spectral ,[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph] ,Fermi Gamma-ray Space Telescope - Abstract
Full list of authors: Acciari, V. A.; Ansoldi, S.; Antonelli, L. A.; Arbet Engels, A.; Artero, M.; Asano, K.; Babić, A.; Baquero, A.; Barres de Almeida, U.; Barrio, J. A.; Batković, I.; Becerra González, J.; Bednarek, W.; Bellizzi, L.; Bernardini, E.; Bernardos, M.; Berti, A.; Besenrieder, J.; Bhattacharyya, W.; Bigongiari, C.; Blanch, O.; Bošnjak, Ž.; Busetto, G.; Carosi, R.; Ceribella, G.; Cerruti, M.; Chai, Y.; Chilingarian, A.; Cikota, S.; Colak, S. M.; Colombo, E.; Contreras, J. L.; Cortina, J.; Covino, S.; D'Amico, G.; D'Elia, V.; da Vela, P.; Dazzi, F.; de Angelis, A.; de Lotto, B.; Delfino, M.; Delgado, J.; Delgado Mendez, C.; Depaoli, D.; di Pierro, F.; di Venere, L.; Do Souto Espiñeira, E.; Dominis Prester, D.; Donini, A.; Doro, M.; Fallah Ramazani, V.; Fattorini, A.; Ferrara, G.; Fonseca, M. V.; Font, L.; Fruck, C.; Fukami, S.; García López, R. J.; Garczarczyk, M.; Gasparyan, S.; Gaug, M.; Giglietto, N.; Giordano, F.; Gliwny, P.; Godinović, N.; Green, J. G.; Green, D.; Hadasch, D.; Hahn, A.; Heckmann, L.; Herrera, J.; Hoang, J.; Hrupec, D.; Hütten, M.; Inada, T.; Inoue, S.; Ishio, K.; Iwamura, Y.; Jiménez, I.; Jormanainen, J.; Jouvin, L.; Kajiwara, Y.; Karjalainen, M.; Kerszberg, D.; Kobayashi, Y.; Kubo, H.; Kushida, J.; Lamastra, A.; Lelas, D.; Leone, F.; Lindfors, E.; Lombardi, S.; Longo, F.; López-Coto, R.; López-Moya, M.; López-Oramas, A.; Loporchio, S.; Machado de Oliveira Fraga, B.; Maggio, C.; Majumdar, P.; Makariev, M.; Mallamaci, M.; Maneva, G.; Manganaro, M.; Maraschi, L.; Mariotti, M.; Martínez, M.; Mazin, D.; Menchiari, S.; Mender, S.; Mićanović, S.; Miceli, D.; Miener, T.; Minev, M.; Miranda, J. M.; Mirzoyan, R.; Molina, E.; Moralejo, A.; Morcuende, D.; Moreno, V.; Moretti, E.; Neustroev, V.; Nigro, C.; Nilsson, K.; Nishijima, K.; Noda, K.; Nozaki, S.; Ohtani, Y.; Oka, T.; Otero-Santos, J.; Paiano, S.; Palatiello, M.; Paneque, D.; Paoletti, R.; Paredes, J. M.; Pavletić, L.; Peñil, P.; Perennes, C.; Persic, M.; Prada Moroni, P. G.; Prandini, E.; Priyadarshi, C.; Puljak, I.; Ribó, M.; Rico, J.; Righi, C.; Rugliancich, A.; Saha, L.; Sahakyan, N.; Saito, T.; Sakurai, S.; Satalecka, K.; Saturni, F. G.; Schmidt, K.; Schweizer, T.; Sitarek, J.; Šnidarić, I.; Sobczynska, D.; Spolon, A.; Stamerra, A.; Strom, D.; Strzys, M.; Suda, Y.; Surić, T.; Takahashi, M.; Tavecchio, F.; Temnikov, P.; Terzić, T.; Teshima, M.; Tosti, L.; Truzzi, S.; Tutone, A.; Ubach, S.; van Scherpenberg, J.; Vanzo, G.; Vazquez Acosta, M.; Ventura, S.; Verguilov, V.; Vigorito, C. F.; Vitale, V.; Vovk, I.; Will, M.; Wunderlich, C.; Zarić, D.; Baack, D.; Balbo, M.; Biederbeck, N.; Biland, A.; Bretz, T.; Buss, J.; Dorner, D.; Eisenberger, L.; Elsaesser, D.; Hildebrand, D.; Iotov, R.; Mannheim, K.; Neise, D.; Noethe, M.; Paravac, A.; Rhode, W.; Schleicher, B.; Sliusar, V.; Walter, R.; D'Ammando, F.; Horan, D.; Lien, A. Y.; Baloković, M.; Madejski, G. M.; Perri, M.; Verrecchia, F.; Leto, C.; Lähteenmäki, A.; Tornikoski, M.; Ramakrishnan, V.; Järvelä, E.; Vera, R. J. C.; Chamani, W.; Villata, M.; Raiteri, C. M.; Gupta, A. C.; Pandey, A.; Fuentes, A.; Agudo, I.; Casadio, C.; Semkov, E.; Ibryamov, S.; Marchini, A.; Bachev, R.; Strigachev, A.; Ovcharov, E.; Bozhilov, V.; Valcheva, A.; Zaharieva, E.; Damljanovic, G.; Vince, O.; Larionov, V. M.; Borman, G. A.; Grishina, T. S.; Hagen-Thorn, V. A.; Kopatskaya, E. N.; Larionova, E. G.; Larionova, L. V.; Morozova, D. A.; Nikiforova, A. A.; Savchenko, S. S.; Troitskiy, I. S.; Troitskaya, Y. V.; Vasilyev, A. A.; Merkulova, O. A.; Chen, W. P; Samal, M.; Lin, H. C.; Moody, J. W.; Sadun, A. C.; Jorstad, S. G.; Marscher, A. P.; Weaver, Z. R.; Feige, M.; Kania, J.; Kopp, M.; Kunkel, L.; Reinhart, D.; Scherbantin, A.; Schneider, L.; Lorey, C.; Acosta-Pulido, J. A.; Carnerero, M. I.; Carosati, D.; Kurtanidze, S. O.; Kurtanidze, O. M.; Nikolashvili, M. G.; Chigladze, R. A.; Ivanidze, R. Z.; Kimeridze, G. N.; Sigua, L. A.; Joner, M. D.; Spencer, M.; Giroletti, M.; Marchili, N.; Righini, S.; Rizzi, N.; Bonnoli, G.; MAGIC Collaboration; Fact Collaboration.-- This is an Open Access article, published by EDP Sciences, under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited., Aims. We present a detailed characterisation and theoretical interpretation of the broadband emission of the paradigmatic TeV blazar Mrk 421, with a special focus on the multi-band flux correlations. Methods. The dataset has been collected through an extensive multi-wavelength campaign organised between 2016 December and 2017 June. The instruments involved are MAGIC, FACT, Fermi-LAT, Swift, GASP-WEBT, OVRO, Medicina, and Metsahovi. Additionally, four deep exposures (several hours long) with simultaneous MAGIC and NuSTAR observations allowed a precise measurement of the falling segments of the two spectral components. Results. The very-high-energy (VHE; E 100 GeV) gamma rays and X-rays are positively correlated at zero time lag, but the strength and characteristics of the correlation change substantially across the various energy bands probed. The VHE versus X-ray fluxes follow dierent patterns, partly due to substantial changes in the Compton dominance for a few days without a simultaneous increase in the X-ray flux (i.e., orphan gamma-ray activity). Studying the broadband spectral energy distribution (SED) during the days including NuSTAR observations, we show that these changes can be explained within a one-zone leptonic model with a blob that increases its size over time. The peak frequency of the synchrotron bump varies by two orders of magnitude throughout the campaign. Our multi-band correlation study also hints at an anti-correlation between UV-optical and X-ray at a significance higher than 3. A VHE flare observed on MJD 57788 (2017 February 4) shows gamma-ray variability on multi-hour timescales, with a factor ten increase in the TeV flux but only a moderate increase in the keV flux. The related broadband SED is better described by a two-zone leptonic scenario rather than by a one-zone scenario.We find that the flare can be produced by the appearance of a compact second blob populated by high energetic electrons spanning a narrow range of Lorentz factors, from 0 min = 2104 to 0 max = 6105. © 2021 Georg Thieme Verlag. All rights reserved., The MAGIC Collaboration would like to thank the Instituto de Astrofísica de Canarias for the excellent working conditions at the Observatorio del Roque de los Muchachos in La Palma. The financial support of the German BMBF, MPG and HGF; the Italian INFN and INAF; the Swiss National Fund SNF; the ERDF under the Spanish Ministerio de Ciencia e Innovación (MICINN) (FPA2017-87859-P, FPA2017-85668-P, FPA2017-82729-C6-5-R, FPA2017-90566-REDC, PID2019-104114RB-C31, PID2019-104114RB-C32, PID2019-105510GB-C31,PID2019-107847RB-C41, PID2019-107847RB-C42, PID2019-107847RB-C44, PID2019-107988GB-C22); the Indian Department of Atomic Energy; the Japanese ICRR, the University of Tokyo, JSPS, and MEXT; the Bulgarian Ministry of Education and Science, National RI Roadmap Project DO1-268/16.12.2019 and the Academy of Finland grant nr. 320045 is gratefully acknowledged. This work was also supported by the Spanish Centro de Excelencia “Severo Ochoa” SEV-2016-0588, SEV-2017-0709 and CEX2019-000920-S, and “María de Maeztu” CEX2019-000918-M, the Unidad de Excelencia “María de Maeztu” MDM-2015-0509-18-2 and the “la Caixa” Foundation (fellowship LCF/BQ/PI18/11630012) and by the CERCA program of the Generalitat de Catalunya; by the Croatian Science Foundation (HrZZ) Project IP-2016-06-9782 and the University of Rijeka Project 13.12.1.3.02; by the DFG Collaborative Research Centers SFB823/C4 and SFB876/C3; the Polish National Research Centre grant UMO-2016/22/M/ST9/00382; and by the Brazilian MCTIC, CNPq and FAPERJ. The important contributions from ETH Zurich grants ETH-10.08-2 and ETH-27.12-1 as well as the funding by the Swiss SNF and the German BMBF (Verbundforschung Astro- und Astroteilchenphysik) and HAP (Helmoltz Alliance for Astroparticle Physics) are gratefully acknowledged. Part of this work is supported by Deutsche Forschungsgemeinschaft (DFG) within the Collaborative Research Center SFB 876 “Providing Information by Resource-Constrained Analysis”, project C3. We are thankful for the very valuable contributions from E. Lorenz, D. Renker and G. Viertel during the early phase of the project. We thank the Instituto de Astrofísica de Canarias for allowing us to operate the telescope at the Observatorio del Roque de los Muchachos in La Palma, the Max-Planck-Institut für Physik for providing us with the mount of the former HEGRA CT3 telescope, and the MAGIC collaboration for their support. The Fermi LAT Collaboration acknowledges generous ongoing support from a number of agencies and institutes that have supported both the development and the operation of the LAT as well as scientific data analysis. These include the National Aeronautics and Space Administration and the Department of Energy in the United States, the Commissariat à l’Energie Atomique and the Centre National de la Recherche Scientifique/Institut National de Physique Nucléaire et de Physique des Particules in France, the Agenzia Spaziale Italiana and the Istituto Nazionale di Fisica Nucleare in Italy, the Ministry of Education, Culture, Sports, Science and Technology (MEXT), High Energy Accelerator Research Organization (KEK) and Japan Aerospace Exploration Agency (JAXA) in Japan, and the K. A. Wallenberg Foundation, the Swedish Research Council and the Swedish National Space Board in Sweden. Additional support for science analysis during the operations phase is gratefully acknowledged from the Istituto Nazionale di Astrofisica in Italy and the Centre National d’Études Spatiales in France. This work performed in part under DOE Contract DE-AC02-76SF00515. This work made use of data from the NuSTAR mission, a project led by the California Institute of Technology, managed by the Jet Propulsion Laboratory, and funded by the National Aeronautics and Space Administration. We thank the NuSTAR Operations, Software, and Calibration teams for support with the execution and analysis of these observations. This research has made use of the NuSTAR Data Analysis Software (NuSTARDAS) jointly developed by the ASI Science Data Center (ASDC; Italy) and the California Institute of Technology (USA). This research has also made use of the XRT Data Analysis Software (XRTDAS) developed under the responsibility of the ASI Science Data Center (ASDC), Italy. A.A.E and D.P acknowledge support from the Deutsche Forschungs gemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – EXC-2094 – 390783311. M. B. acknowledges support from the YCAA Prize Postdoctoral Fellowship and from the Black Hole Initiative at Harvard University, which is funded in part by the Gordon and Betty Moore Foundation (grant GBMF8273) and in part by the John Templeton Foundation. This publication makes use of data obtained at the Metsähovi Radio Observatory, operated by Aalto University in Finland. This research has made use of data from the OVRO 40-m monitoring program (Richards et al. 2011) which is supported in part by NASA grants NNX08AW31G, NNX11A043G, and NNX14AQ89G and NSF grants AST-0808050 and AST-1109911. I.A. acknowledges financial support from the Spanish “Ministerio de Ciencia e Innovación” (MCINN) through the “Center of Excellence Severo Ochoa” award for the Instituto de Astrofísica de Andalucía-CSIC (SEV-2017-0709). Acquisition and reduction of the MAPCAT data was supported in part by MICINN through grants AYA2016-80889-P and PID2019-107847RB-C44. The MAPCAT observations were carried out at the German-Spanish Calar Alto Observatory, which is jointly operated by Junta de Andalucía and Consejo Superior de Investigaciones Científicas. C.C. acknowledges support from the European Research Council (ERC) under the European Union Horizon 2020 research and innovation program under the grant agreement No 771282. This research was partially supported by the Bulgarian National Science Fund of the Ministry of Education and Science under grants KP-06-H28/3 (2018), KP-06-H38/4 (2019) and KP-06-KITAJ/2 (2020). We acknowledge support by Bulgarian National Science Fund under grant DN18-10/2017 and National RI Roadmap Projects DO1-277/16.12.2019 and DO1-268/16.12.2019 of the Ministry of Education and Science of the Republic of Bulgaria. This research was supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia (contract No 451-03-68/2020-14/200002). G.D. acknowledges observing grant support from the Institute of Astronomy and Rozhen NAO BAS through the bilateral joint research project “Gaia Celestial Reference Frame (CRF) and fast variable astronomical objects” (2020–2022, head – G. Damljanovic). The BU group was supported in part by NASA Fermi guest investigator program grants 80NSSC19K1505 and 80NSSC20K1566. This study was based in part on observations conducted using the 1.8 m Perkins Telescope Observatory (PTO) in Arizona, which is owned and operated by Boston University. This article is partly based on observations made with the LCOGT Telescopes, one of whose nodes is located at the Observatorios de Canarias del IAC on the island of Tenerife in the Observatorio del Teide. This article is also based partly on data obtained with the STELLA robotic telescopes in Tenerife, an AIP facility jointly operated by AIP and IAC. The Abastumani team acknowledges financial support by the Shota Rustaveli National Science Foundation under contract FR-19-6174. Based on observations with the Medicina telescope operated by INAF – Istituto di Radioastronomia.
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- 2021
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30. Formation of DNA Damage Foci in Human and Mouse Primary Fibroblasts Chronically Exposed to Gamma Radiation at 0.1 mGy/min.
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Zaharieva E, Sasatani M, Matsumoto R, and Kamiya K
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- Animals, Cells, Cultured, Dose-Response Relationship, Radiation, Fibroblasts metabolism, Humans, Male, Mice, Mice, Inbred C57BL, DNA Breaks, Double-Stranded, Fibroblasts radiation effects, Gamma Rays
- Abstract
Low-dose-rate radiation exposures and their associated cancer risk are an important concern for radiation protection today. Nevertheless, there is almost no data concerning DNA damage at dose rates below 0.1 mGy/min. In this study, we investigated the formation of DNA damage repair foci under chronic low-dose-rate irradiation relative to acute high-dose-rate irradiation and assessed the magnitude of the dose-rate effect. Four human and four mouse normal fibroblast cell models from different organs were subjected to gamma irradiation at 0.096 mGy/min or 0.81 Gy/min, and dose-response curves were established for the dose range from 0.1 to 0.8 Gy. The results indicate that prolonged low-dose-rate exposures cause modestly increased levels of DNA repair foci, with a strongly supralinear dose-response relationship, where 40-70% of the radiation effect at 1 Gy was already present at the total dose of 0.1 Gy. Thus, compared to acute irradiation, low-dose-rate exposure was 6-9 times less efficient at a total dose of 0.1 Gy, and 10-20 times less efficient at 1 Gy. Comparison between cell models revealed a certain correlation between the presence of persistent, above-background foci at 48 h after irradiation and the sensitivity to low-dose-rate radiation, suggesting that repair capacity plays an important role in the cellular response to chronic irradiation. Given the findings reported here, we propose that establishing detailed dose-response curves and accounting for the repair rates of different cell models are essential steps in elucidating dose-rate effects., (©2021 by Radiation Research Society. All rights of reproduction in any form reserved.)
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- 2021
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31. Circular RNA circRNF20 promotes breast cancer tumorigenesis and Warburg effect through miR-487a/HIF-1α/HK2.
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Cao L, Wang M, Dong Y, Xu B, Chen J, Ding Y, Qiu S, Li L, Karamfilova Zaharieva E, Zhou X, and Xu Y
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- 3' Untranslated Regions, Animals, Binding Sites, Breast Neoplasms genetics, Breast Neoplasms pathology, Cell Proliferation, Female, Gene Expression Regulation, Neoplastic, Hexokinase genetics, Humans, Hypoxia-Inducible Factor 1, alpha Subunit genetics, MCF-7 Cells, Mice, Nude, MicroRNAs genetics, Middle Aged, RNA, Circular genetics, Signal Transduction, Transcription, Genetic, Breast Neoplasms metabolism, Hexokinase metabolism, Hypoxia-Inducible Factor 1, alpha Subunit metabolism, MicroRNAs metabolism, RNA, Circular metabolism, Warburg Effect, Oncologic
- Abstract
Compelling evidence has demonstrated the potential functions of circular RNAs (circRNAs) in breast cancer (BC) tumorigenesis. Nevertheless, the underlying mechanism by which circRNAs regulate BC progression is still unclear. The purpose of present research was to investigate the novel circRNA circRNF20 (hsa_circ_0087784) and its role in BC. CircRNA microarray sequencing revealed that circRNF20 was one of the upregulated transcripts in BC samples. Increased circRNF20 level predicted the poor clinical outcome in BC specimens. Functionally, circRNF20 promoted the proliferation and Warburg effect (aerobic glycolysis) of BC cells. Mechanistically, circRNF20 harbor miR-487a, acting as miRNA sponge, and then miR-487a targeted the 3'-UTR of hypoxia-inducible factor-1α (HIF-1α). Moreover, HIF-1α could bind with the promoter of hexokinase II (HK2) and promoted its transcription. In conclusion, this finding illustrates the vital roles of circRNF20 via the circRNF20/ miR-487a/HIF-1α/HK2 axis in breast cancer progress and Warburg effect, providing an interesting insight for the BC tumorigenesis.
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- 2020
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32. Inflammatory profile dysregulation in nuclear workers occupationally exposed to low-dose gamma radiation.
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Aneva N, Zaharieva E, Katsarska O, Savova G, Stankova K, Djounova J, and Boteva R
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- Adult, Antioxidants metabolism, Case-Control Studies, Cytokines blood, Dose-Response Relationship, Radiation, Humans, Hypertension blood, Linear Models, Male, Middle Aged, Gamma Rays, Inflammation pathology, Nuclear Power Plants, Occupational Exposure analysis, Radiation Exposure analysis
- Abstract
Chronic inflammation is a common denominator linking a wide range of health conditions, including tissue response to radiation exposure. This pilot study investigates whether inflammatory cytokines-interleukins IL-6, -8, -10, monocyte chemoattractant protein-1 (MCP-1) and tumor necrosis factor α (TNFα)-can be used as early biomarkers of radiation-induced adverse health effects in occupationally exposed individuals. The study included 33 workers externally exposed to gamma radiation from the nuclear industry with cumulated doses from 0.11 to 190 mSv and 42 non-exposed controls of comparable age and socio-economic status. IL-6, IL-8, MCP-1, TNFα and IL-10 were analyzed by enzyme-linked assay (ELISA) in blood plasma samples. Total antioxidant status (TAS) of blood plasma was determined by a colorimetric assay. The radiation-exposed and control groups measured significantly different levels of MCP-1, TNFα and IL-10. Seventy-five percent of radiation workers had either high MCP-1 levels or low IL-10 levels and 30% had all three cytokines dysregulated. Approximately 50% of workers showed upregulated antioxidant status, which appeared to compensate the pro-inflammatory cytokine shift in these individuals. In contrast, only 2% of the control subjects were found to have three dysregulated cytokines, and all of them measured within the normal TAS range. The present study may represent an important step towards the establishment of a reliable set of biomarkers for health-risk estimation in population cohorts exposed to low radiation doses., (© The Author(s) 2019. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.)
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- 2019
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33. Reduced soluble Toll-like receptors 2 in type 2 diabetes.
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Zaharieva E, Velikova T, Tsakova A, and Kamenov Z
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- Biomarkers blood, Bulgaria, C-Reactive Protein analysis, Cross-Sectional Studies, Diabetes Mellitus, Type 2 immunology, Enzyme-Linked Immunosorbent Assay, Female, Glycated Hemoglobin analysis, Hospitals, University, Humans, Interleukin-6 blood, Male, Middle Aged, Outpatient Clinics, Hospital, Solubility, Toll-Like Receptor 2 chemistry, Toll-Like Receptor 4 blood, Toll-Like Receptor 4 chemistry, Tumor Necrosis Factor-alpha blood, Up-Regulation, Diabetes Mellitus, Type 2 blood, Down-Regulation, Toll-Like Receptor 2 blood
- Abstract
Background: Soluble forms of Toll-like receptors (sTLR) 2 and 4 exert negative regulatory control on membrane-bound receptor activation. The study estimates the sTLR2 and sTLR4's serum levels in type 2 diabetes (T2D) and evaluates their relationship with metabolic and inflammatory parameters., Subjects and Methods: Sixty three patients with T2D and 25 controls were enrolled. sTLR were assayed through ELISA. Inflammatory markers included Interleukin 6 (IL-6), high sensitivity C-reactive protein (hs-CRP) and tumour necrosis factor α., Results: Analysis demonstrated lower sTLR2 level in T2D than in control subjects (1.15 ± 0.65 versus 1.44 ± 0.60 ng/ml, p = .019) while sTLR4 level remained similar (0.09 ± 0.16 versus 0.07 ± 0.12 ng/ml, p > .05) despite higher IL-6 (2.65 ± 2.46 versus 1.44 ± 0.22 pg/ml, p = .005) and hs-CRP (2.79 ± 2.89 versus 0.70 ± 0.89 mg/l, p < .001) concentrations. Neither sTLR correlated with BMI, HbA1c, plasma glucose and analysed cytokines (p > .05)., Conclusion: The sTLR2 serum level in T2D patients was reduced despite elevated inflammatory parameters.
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- 2018
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34. Interleukin-18 serum level is elevated in type 2 diabetes and latent autoimmune diabetes.
- Author
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Zaharieva E, Kamenov Z, Velikova T, Tsakova A, El-Darawish Y, and Okamura H
- Abstract
Background: Interleukin-18 (IL-18) is an inflammatory cytokine found to be elevated in obesity, metabolic syndrome and type 2 diabetes (T2D) as a part of the chronic low-grade inflammatory process in these states. The aim of the study was to evaluate the interleukin level in patients with latent autoimmune diabetes of the adults (LADA) in comparison to that in T2D subjects., Materials and Methods: IL-18 was analyzed through enzyme-linked immunosorbent assay in 76 participants with T2D and 24 with LADA and 14 control subjects. Evaluation was also carried out in body mass index (BMI)- and glycemic control-matched diabetic patients., Results: The serum concentration of IL-18 was higher in patients with T2D (389.04 ± 203.44 pg/mL) and LADA (327.04 ± 144.48 pg/mL) than that in control subjects (219.88 ± 91.03 pg/mL), P < 0.05. However, it was not significantly different between both diabetic groups ( P = 0.255) despite higher IL-6 (4.78 ± 5.84 vs 1.79 ± 0.96 pg/mL, P < 0.001) and hs-CRP (2.60 ± 1.70 vs 1.29 ± 1.20 mg/L, P = 0.002) level in T2D patients. The results were persistent in BMI-matched subjects with diabetes (IL-18 = 403.48 ± 226.32 vs 329.30 ± 146.30 pg/mL, respectively for T2D and LADA, P = 0.391). The correlations in T2D group concerning HDL cholesterol ( r = -0.377, P = 0.001), postprandial glucose ( r = 0.244, P = 0.043), IL-6 ( r = 0.398, P < 0.001) and hs-CRP ( r = 0.427, P = 0.001) were not confirmed in LADA and control subjects., Conclusion: The IL-18 serum level was higher in T2D and LADA than that in control subjects, but did not differ between both diabetic groups, even when they were BMI matched. Correlations with lipid, glycemic and inflammatory parameters were present in T2D only., (© 2018 The authors.)
- Published
- 2018
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35. Concomitant insulinoma and type 2 diabetes mellitus diagnoses: a case report.
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Assyov Y, Gateva A, Zaharieva E, Tsakova A, Tournev I, Kyoseva D, Bulanov D, Arabadjieva E, Dimitrova V, Krupev M, and Kamenov Z
- Subjects
- Blood Glucose metabolism, Diabetes Mellitus, Type 2 blood, Diabetes Mellitus, Type 2 complications, Female, Humans, Insulin blood, Insulinoma complications, Insulinoma surgery, Middle Aged, Pancreatectomy methods, Pancreatic Neoplasms complications, Pancreatic Neoplasms surgery, Splenectomy methods, Treatment Outcome, Diabetes Mellitus, Type 2 diagnosis, Insulinoma diagnosis, Pancreatic Neoplasms diagnosis
- Published
- 2016
- Full Text
- View/download PDF
36. The soluble receptor ST2 is positively associated with occupational exposure to radiation.
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Katsarska O, Zaharieva E, Aneva N, Savova G, Stankova K, and Boteva R
- Subjects
- Absorption, Radiation, Adult, Biomarkers blood, Cells, Cultured, Dose-Response Relationship, Radiation, Female, Humans, Interleukin-1 Receptor-Like 1 Protein, Male, Middle Aged, Radiation Dosage, Lymphocytes metabolism, Lymphocytes radiation effects, Occupational Exposure analysis, Radiation Exposure analysis, Reactive Oxygen Species blood, Receptors, Cell Surface blood
- Abstract
Purpose Radiation exposure, besides the risk of cancer, may also increase the risk of non-cancer diseases, including cardiovascular disease (CVD). This study investigates whether the soluble form of the ST2 receptor (sST2), an emerging prognostic marker in patients with CVD, can be used to monitor the CVD risk in individuals occupationally exposed to radiation. Materials and methods sST2 in blood plasma from 69 individuals, 45 workers from the nuclear industry and 24 controls, was analyzed using enzyme-linked assay (ELISA). Total antioxidant status (TAS) of blood plasma and levels of reactive oxygen species (ROS) in lymphocytes were determined by colorimetric and fluorescence assays. Results The data suggest a 5-fold increase in the number of subjects with sST2 levels above the clinical threshold and a 10-fold increase in the number of subjects with TAS levels outside the reference range in the exposed group when compared to the group of non-exposed individuals. The strongest up-regulation of TAS was measured in the group of younger workers with cumulative doses not exceeding 50 mSv. Conclusion The present study may represent an initial step towards the establishment of sST2 as a biomarker for CVD risk estimation in the context of radiation exposure.
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- 2016
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37. Concentration and Localization of Coexpressed ELAV/Hu Proteins Control Specificity of mRNA Processing.
- Author
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Zaharieva E, Haussmann IU, Bräuer U, and Soller M
- Subjects
- Alternative Splicing genetics, Animals, Drosophila Proteins biosynthesis, ELAV Proteins genetics, Eye embryology, Gene Expression Regulation genetics, Nerve Tissue Proteins biosynthesis, Protein Binding, RNA-Binding Proteins biosynthesis, Sex Differentiation genetics, Wings, Animal cytology, Drosophila Proteins genetics, Drosophila Proteins metabolism, Drosophila melanogaster genetics, ELAV Proteins metabolism, Nerve Tissue Proteins genetics, Nerve Tissue Proteins metabolism, Neurogenesis genetics, RNA-Binding Proteins genetics, RNA-Binding Proteins metabolism
- Abstract
Neuronally coexpressed ELAV/Hu proteins comprise a family of highly related RNA binding proteins which bind to very similar cognate sequences. How this redundancy is linked to in vivo function and how gene-specific regulation is achieved have not been clear. Analysis of mutants in Drosophila ELAV/Hu family proteins ELAV, FNE, and RBP9 and of genetic interactions among them indicates that they have mostly independent roles in neuronal development and function but have converging roles in the regulation of synaptic plasticity. Conversely, ELAV, FNE, RBP9, and human HuR bind ELAV target RNA in vitro with similar affinities. Likewise, all can regulate alternative splicing of ELAV target genes in nonneuronal wing disc cells and substitute for ELAV in eye development upon artificially increased expression; they can also substantially restore ELAV's biological functions when expressed under the control of the elav gene. Furthermore, ELAV-related Sex-lethal can regulate ELAV targets, and ELAV/Hu proteins can interfere with sexual differentiation. An ancient relationship to Sex-lethal is revealed by gonadal expression of RBP9, providing a maternal fail-safe for dosage compensation. Our results indicate that highly related ELAV/Hu RNA binding proteins select targets for mRNA processing through alteration of their expression levels and subcellular localization but only minimally by altered RNA binding specificity., (Copyright © 2015, American Society for Microbiology. All Rights Reserved.)
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- 2015
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38. Regulation of ELAV/Hu RNA-binding proteins by phosphorylation.
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Bräuer U, Zaharieva E, and Soller M
- Subjects
- Alternative Splicing physiology, Animals, ELAV Proteins genetics, Humans, Phosphorylation, ELAV Proteins metabolism
- Abstract
ELAV (embryonic lethal/abnormal visual system)/Hu proteins comprise a family of highly related neuronal RBPs (RNA-binding proteins) involved in many aspects of mRNA processing. Although they bind to highly similar short sequence motifs, they have acquired diverse functions suggesting that cellular signalling is important for their functional diversification. Indeed, ELAV/Hu proteins harbour many phosphorylatable amino acids. In the present article, we review our current knowledge about phosphorylation of ELAV/Hu proteins and how phosphorylation affects cellular localization of ELAV/Hu proteins and their binding to RNA.
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- 2014
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39. Alternative splicing interference by xenobiotics.
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Zaharieva E, Chipman JK, and Soller M
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- Animals, Humans, Neoplasms genetics, Neurodegenerative Diseases genetics, Alternative Splicing drug effects, Drug-Related Side Effects and Adverse Reactions, Xenobiotics toxicity
- Abstract
The protein coding sequence of most eukaryotic genes (exons) is interrupted by non-coding parts (introns), which are excised in a process termed splicing. To generate a mature messenger RNA (mRNA) hundreds of combinatorial protein-protein and RNA-protein interactions are required to splice out often very large introns with high fidelity and accuracy. Inherent to splicing is the use of alternative splice sites generating immense proteomic diversity from a limited number of genes. In humans, alternative splicing is a major mode of regulating gene expression, occurs in over 90% of genes and is particularly abundant in the brain. Only recently, it has been recognized that the complexity of the splicing process makes it susceptible to interference by various xenobiotics. These compounds include antineoplastic substances, commonly used drugs and food supplements and cause a spectrum of effects ranging from deleterious inhibition of general splicing to highly specific modifications of alternative splicing affecting only certain genes. Alterations in splicing have been implicated in numerous diseases such as cancer and neurodegeneration. Splicing regulation plays an important role in the execution of programmed cell death. The switch between anti- and pro-apoptotic isoforms by alternative splice site selection and misregulation of a number of splicing factors impacts on cell survival and disease. Here, our current knowledge is summarized on compounds interfering with general and alternative splicing and of the current methodology to study changes in these processes relevant to the field of toxicology and future risk assessments., (Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.)
- Published
- 2012
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40. Hepatitis C virus infection: a possible promoting agent in porphyria cutanea tarda.
- Author
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Antonov K, Krastev Z, Teoharov P, Zaharieva E, Alexiev A, Ivanova A, and Adjarov D
- Subjects
- Adult, Aged, Bulgaria, Enzyme-Linked Immunosorbent Assay, Female, Follow-Up Studies, Hepatitis C virology, Humans, Immunoblotting, Iron therapeutic use, Male, Middle Aged, Porphyria Cutanea Tarda diagnosis, Porphyria Cutanea Tarda therapy, Prevalence, Recurrence, Risk Factors, Hepacivirus immunology, Hepatitis C complications, Hepatitis C Antibodies analysis, Porphyria Cutanea Tarda virology
- Abstract
The study aimed to differentiate the factors triggering porphyria cutanea tarda, paying special attention to the presumed role of hepatitis C virus infection. In a representative Bulgarian contingent, HCV-antibodies were identified using ELISA II and immunoblot. Seropositivity was significantly higher (p < 0.01) in the sporadic form (36 out of 57 patients; 63.2%) compared with the familiar form (4 out of 20 subjects; 20%). Alcohol abuse was the most common factor preceding the expression of open porphyria both in the sporadic and the familiar forms. In 10 sporadic cases, no precipitating factors were observed, except for the fact that they were anti-HCV positive. In another 2 anti-HCV positive patients, porphyria cutanea tarda was preceded by blood transfusions. Renewed consumption of alcohol after successful treatment was a common reason for relapse, but relapses were most frequent in anti-HCV positive patients (35 relapses in 12 patients), in whom other promoting factors were absent. Analysis of triggering factors shows that most probably hepatitis C virus infection could contribute to the expression of porphyria cutanea tarda and the association of both diseases is not coincidental.
- Published
- 1996
41. Rofficerone: A New Triterpenoid from Rosmarinus officinalis.
- Author
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Ganeva Y, Tsankova E, Simova S, Apostolova B, and Zaharieva E
- Published
- 1993
- Full Text
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42. Study on immunological reactivity of mice treated with antigen from ascitic form of Ehrlich carcinoma.
- Author
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Botev B, Marholev L, Zaharieva E, and Golemanova E
- Subjects
- Animals, Hemolytic Plaque Technique, Lymphocytes immunology, Mice, Antibody Formation, Antigens, Carcinoma, Ehrlich Tumor immunology, Spleen immunology
- Published
- 1970
43. Survey of sportswomen at the Tokyo Olympics.
- Author
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Zaharieva E
- Subjects
- Adolescent, Adult, Female, Humans, Statistics as Topic, Menstruation, Sports Medicine, Women
- Published
- 1965
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