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2 results on '"Yan-Na Xiao"'

1. Tropism and Infectivity of Pandemic Influenza A H1N1/09 Virus in the Human Placenta

Author

Yan-Na Xiao, Fei-Yuan Yu, Qian Xu, and Jiang Gu

Subjects
influenza A virus, pdmH1N1, human placenta, Microbiology, QR1-502
Abstract

Influenza virus infection in pregnant women may put the fetus at higher risk; however, to date, there has been no detailed research about the expression of influenza virus receptors in the human placenta. We employed the lectin staining technique, which is a classic influenza virus receptor research method for studying the distribution of viral receptors in the human placenta. In addition, we examined the susceptibility of the human placenta to H1N1/09, by detecting viral proteins and RNA at different time points post-infection. We found that the human placenta expressed both avian and human influenza A virus receptors (α-2, 3-linked sialic acid and α-2, 6-linked sialic acid). In addition, H1N1/09 did not only infect the human placenta, but also replicated and was released into the culture media. We concluded that the human placenta is susceptible to the 2009 influenza A virus (H1N1/09) infection, and that particular attention should be paid to shielding pregnant women from infection during influenza season.

Published
2022
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2. Study on Na2O-B2O3-SiO2-CaO-P2O5-F System Glass-Ceramics

Author

Ming Shun Zhang, Yan Na Xiao, Jian Guo Jin, and Wen Li Zhang

Subjects
Quenching, Materials science, Mechanical Engineering, Simulated body fluid, Mineralogy, Sintering, Molding (process), Microstructure, law.invention, Chemical engineering, Mechanics of Materials, law, visual_art, Phase (matter), visual_art.visual_art_medium, General Materials Science, Ceramic, Crystallization
Abstract

This paper studied the Na2O-B2O3-SiO2-CaO-P2O5-F glass-ceramics and obtained the complex biological glass-ceramics with low sintering temperature, high mechanical properties and good biological activity. In this paper, the better basic point was selected in phase region of Na2O-B2O3-SiO2 glass system. It was studied that the effect of different percent of CaO, P2O5 and F addition on the mechanical properties and biological activity of the glass-ceramics. The glass powder was prepared by melting and quenching in water, and then by molding and sintering, composite glass-ceramics materials was obtained. With the help of DSC, XRD and SEM analysis methods and testing means, the phases and heat treatment systems of the material were determined, and the microstructure of materials in the different heat treatment conditions was observed. The biological activity was tested in SBF simulated body fluid . Research shows that: the introduction of F can effectively reduce the melting temperature of the material and is helpful to crystallization. The introduction amount of CaO, P2O5 and F can affect the biological activity of glass-ceramics. In the range of introducing CaO, P2O5 and F in this paper, the mechanical properties and biological activity of glass-ceramics increase with the amount of the introduction of CaO, P2O5 and F.

Published
2013

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