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We consider the holographic QCD model with a planar horizon in the D dimensions with different consistent metric solutions. We investigate the black hole thermodynamics, phase diagram and equations of state (EoS) in different dimensions. The temperature and chemical potential dependence of the drag force and diffusion coefficient also have been studied. From the results, the energy loss of heavy quark shows an enhancement near the phase transition temperature in D dimensions. This finding illustrates that the energy loss of heavy quark has a nontrivial and non-monotonic dependence on temperature. Furthermore, we find the heavy quark may lose less energy in higher dimension. The diffusion coefficient is larger in higher dimension., 31 pages, 17 figures, version accepted for publication in European Physical Journal C

Background: Double-hit lymphoma (DHL) is a rare high-grade B-cell lymphoma characterized by MYC and Bcl-2 or Bcl-6 gene translocations. The treatment of DHL remains a substantial clinical challenge due to remarkably undesirable outcomes. Innovative drugs or combination treatment strategies need to be developed to improve the prognosis of DHL patients. The purpose of this study was to investigate the combination treatment of a novel Aurora kinase A (Aurka) inhibitor, named alisertib (MLN8237) and a selective Bcl-2 inhibitor, named ABT-199 in vitro, and to explore the underlying mechanisms in human DHL cell lines. Methods: Cell proliferation was assessed using MTS assay in DHL cells treated with alisertib and ABT-199. Synergistic effects between two drugs were analyzed based on combination index (CI) values. Cell cycle and apoptosis were detected through flow cytometry. The expression of drug-targeted proteins, cell-cycle proteins as well as apoptosis-related proteins were detected by Western blot. Results: Alisertib and ABT-199 alone exhibited a relatively modest cytotoxicity in a concentration- and time-dependent manner, but the combination treatment produced stronger antitumor efficacy and synergistically suppressed the DHL cell growth. Otherwise, the combination treatment between alisertib and ABT-199 arrested the cell cycle in the G2/M phase at respectively lower concentrations (2/5 IC50), while the higher concentrations (3/5 IC50) resulted in a striking increase of cell apoptosis. Further studies demonstrated that both alisertib and ABT-199 downregulated the expression of cyclin-dependent kinase 1 (CDK1) and cyclin B1, but upregulated the p21 and p53 expression. The combination treatment enhanced the expression of cell intrinsic apoptotic proteins, including cleaved Poly ADP-ribose polymerase (PARP) and caspase-3. In addition, the combination treatment almost completely inhibited the expression of drug-targeted proteins, including MYC and Aurka phosphorylation. However, alisertib and ABT-199 did not alter the Bcl-2 expression. Conclusions: Alisertib and ABT-199 had synergistic effects on the inhibition of cell viability, induction of cell G2/M phase arrest and apoptosis in DHL cells. The underlying mechanism of synergism was associated with the p53/p21 and cell intrinsic apoptotic pathways. Our findings suggested that co-targeting Aurka and Bcl-2 might be a potentially therapeutic strategy for DHL lymphoma.

Using the Damour-Ruffini method, Hawking radiation of charged particles from squashed charged rotating five-dimensional Kaluza-Klein black holes is investigated extensively. Under the generalized tortoise coordinate transformation, Hawking temperature of the black holes is calculated by using charged scalar particles and Dirac fermions respectively. We find that the obtained Hawking temperature for charged Dirac fermions is the same as for charged scalar particles. What’s more, the spectrum of Hawking radiation contains the information of the size of the extra dimension, which could provide insight for further investigation of large extra dimensions in the future.

In order to promote the research on erbium-doped fiber’s anti-radiation properties and fully grasp variation laws of erbium-doped fiber’s properties under radiation, theoretical analysis on how irradiation effect erbium-doped Fiber based on model of color centers was conducted. The performance changes of erbium-doped fiber that may occur during irradiation were predicted. According to working principle and application characteristics, online real-time monitoring of 980 nm wave band loss spectra, 1 550 nm wave band loss spectra, luminescence spectra of two different types(EDF-L-980 and MP980) of erbium-doped fiber as well as recovery measuring after radiation were carried out,. Studies showed that spectral characteristics of both types have similar variation trends during radiation. Losses at 980 and 1 530 nm wave band increase monotonically with dose, and the relationship is approximately linear at absorption peak of 980 and 1 530 nm; luminescence spectra intensity decreases monotonically with dose, and energy of luminescence spectra is shifting to long wavelengths, while its mean wavelength and bandwidth increasing substantially. The relationship between luminescence intensity and dose is also approximately linear at luminescence peak of 1 530 nm. Erbium-doped fiber’s spectral characteristics recovered modestly after radiation, but to a limited extent of less than 40% for all parameters. The experiment result is in good agreement with theoretical analysis and prediction, so rationality of theoretical explanation of erbium-doped fiber’s performance changes during radiation has been proven.

In scientific research and engineering application, improving the power of fiber device is an important topic, which leads to observably rise of temperature in fiber core at the same time. In this paper, Thermal effect and its influence on absorption spectrum and lifetime of Erbium-doped fiber are studied with numerical modeling. Lorentz broadening of sub-levels is used to build the mathematical relationship between temperature and absorption spectrum. The McCumber Theory is applied to deduce the lifetime of Erbium-doped fiber in different temperature. Temperature experiments of absorption and emission spectrum from 25 to 900 ℃ are carried out, which show that the wavelength of absorption peak near 980nm increase at rate of 0.625 nm/100 ℃, the ratio of absorption peak near 1 530 nm declines at a rate of 0.001 9 dB·(m℃)-1 and the broadband of absorption spectrum near 1 530 nm increase with rising temperature. The linear variation of lifetime and peak absorption in experiment proves that the theoretical model is reasonable when the temperature is below 600 ℃.

set of shell is an important process on lithium battery production line. Research is applicable to automatic set of lithium battery shell of an organization, the installed baffle set into the very core of battery shell, do not harm the very core, set into the very core of the exposed aluminum shell of the same length. This article put forward from the aspects of kinematics and dynamics of multiple optimization objectives, work in a given space and a variety of constraint conditions, with the aid of the NSGA - II algorithm to complete set of shell machine structure parameters optimization, experiments show that the casing precision of the equipment, set of shell and the percent of pass is up to 99 above, has a certain practical significance.

This paper focuses on a intelligent performance testing system for lithium battery casting. The testing system can automatically cast the lithium battery in order to change its performances when it drops to the ground and suffers a major collision, at the same time, the testing system can test the changing performances. What is more, the paper gives the design project of the automatic casting mechanism and its optimizing method, improving PID controller, and parameters experiment method. The experimental results show that the testing system can successfully and accurately cast the lithium, it meets the technology requirements, furthermore, it can obtain the accurate testing datas

We probe the shock wave geometry with the mutual correlation in a spherically symmetric Reissner Nordstr\"om AdS black hole on the basis of the gauge/gravity duality. In the static background, we find that the regions living on the boundary of the AdS black holes are correlated provided the considered regions on the boundary are large enough. We also investigate the effect of the charge on the mutual correlation and find that the bigger the value of the charge is, the smaller the value of the mutual correlation will to be. As a small perturbation is added at the AdS boundary, the horizon shifts and a dynamical shock wave geometry forms after long time enough. In this dynamic background, we find that the greater the shift of the horizon is, the smaller the mutual correlation will to be. Especially for the case that the shift is large enough, the mutual correlation vanishes, which implies that the considered regions on the boundary are uncorrelated. The effect of the charge on the mutual correlation in this dynamic background is found to be the same as that in the static background., Comment: 10 pages

Liquid phase sintering is used to optimize the magnetic properties and temperature stability of (SmGdDy)(Co, Fe, Cu, Zr) z sintered magnet. DyCo 0.51 and Sm 0.67 Dy 0.11 Gd 0.22 (Co 0.693 Fe 0.201 Cu 0.081 Zr 0.0252 ) 7.94 alloys are chosen as liquid phase and main phase, respectively. (SmGdDy)(Co, Fe, Cu, Zr) z permanent magnets are prepared with different content of liquid phase. XRD analysis shows that all magnets consist of Th 2 Zn 17 -type phase and CaCu 5 -type phase. Cellular structure studies indicate that the H1-5 cell boundary phase shifts gradually from thin and part of discontinuous to thick and continuous. The cell size decreases with the increase of the content of liquid phase. In addition, the Cu content in cell boundary phase is getting lower with the increase of LP adding ratio. The homogeneous and continuous cellular structure is got when the adding ratio of liquid phase is 3 wt% and the highest intrinsic coercivity is achieved at room temperature (23.88 kOe) and 200 °C (12.06 kOe). It’s interesting to find that temperature dependence of remanence ( α ) and the temperature dependence of intrinsic coercivity ( β ) can be optimized with the increase of the content of liquid phase, in which the α (20–100 °C) and β (20–200 °C) are −0.0075%/°C and −0.140%/°C for the magnet with 5 wt% liquid phase, and −0.016%/°C and −0.322%/°C for the magnet with 1 wt% liquid phase.

In this paper, phase transition of AdS black holes in lorentz breaking massive gravity has been studied in the framework of holography. We find that there is a first order phase transition(FPT) and second order phase transition(SPT) both in Bekenstein-Hawking entropy(BHE)-temperature plane and holographic entanglement entropy(HEE)-temperature plane. Furthermore, for the FPT, the equal area law is checked and for the SPT, the critical exponent of the heat capacity is also computed. Our results confirm that the phase structure of HEE is similar to that of BHE in lorentz breaking massive gravity, which implies that HEE and BHE have some potential underlying relationship., 10 pages, 10 figures

// Yao-Li Cui 1, 2 , Li-Hua Qiu 1 , Shi-Yong Zhou 1 , Lan-Fang Li 1 , Zheng-Zi Qian 1 , Xian-Ming Liu 1 , Hui-Lai Zhang 1 , Xiu-Bao Ren 3 and Yong-Qiang Wang 2 1 Department of Lymphoma, Tianjin’s Clinical Research Center for Cancer and Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin 300060, China 2 Department of Intensive Care Unit and Key Laboratory for Critical Care Medicine of The Ministry of Health, Emergency Medicine Research Institute, Tianjin First Center Hospital, Tianjin 300192, China 3 Department of Biotherapy, Key Laboratory of Cancer Immunology and Biotherapy and Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin 300060, China Correspondence to: Hui-Lai Zhang, email: zhlwgq@126.com Xiu-Bao Ren, email: renxiubao1111@163.com Yong-Qiang Wang, email: wangyongqiang1100@163.com Keywords: multiple organ dysfunction syndrome, necroptosis, necrosome, high-mobility group box 1, mixed-lineage kinase domain-like Received: March 24, 2017 Accepted: April 17, 2017 Published: May 29, 2017 ABSTRACT Purpose: To investigate how necroptosisis, i.e. programmed necrosis, is involved in MODS, and to examine whether Nec-1, a specific necroptosis inhibitor, ameliorates multiorgan injury in MODS. Experimental Design: A model of MODS was established in six-week old SD rats using fracture trauma followed by hemorrhage. Control animals received sham surgery. Cell death form and necrosome formation were measured by fluorescence-activated cell sorting and western blotting. MODS rats were randomly assigned to receive Nec-1 or saline with pretreatment and once daily. The first end-point was 72 hours survival. Organ injury and dysfunction, inflammatory cytokine levels, and necroptotic execution protein expression were also recorded. Results: Organ injury and dysfunction were significantly more severe in the MODS group than the sham group (all p

The magnetic and mechanical properties of sintered Nd-Fe-B magnets prepared by different sintering processes were investigated. The results showed that the intrinsic coercivity and fracture toughness of sintered Nd-Fe-B magnets first increased, and then declined with increasing annealing temperature. The optimum magnetic properties and fracture toughness of sintered Nd-Fe-B magnets were obtained at the annealing temperature of 540 degrees C. Sintering temperature increasing from 1047 degrees C to 1071 degrees C had hardly effect on the magnetic properties of sintered Nd-Fe-B magnets. The variation of Vickers hardness and fracture toughness was not the same with increasing sintering temperature, and the effect of sintering temperature on the mechanical properties was complex and irregular. The reasons for the variation on magnetic and mechanical properties were analyzed, and we presumed that the effect of microstructure on the mechanical properties was more sensitive than the magnetic properties through analyzing the microstructure of sintered Nd-Fe-B magnets. (C) 2014 Elsevier B.V. All rights reserved.

Synthesis of Ag-doped magnetic composites with antibacterial properties is in the great interest in the development of new biomedical applications. Ag/γ-Fe2O3 composite microspheres have been successfully prepared via a simple solvothermal reduction method under mild conditions. The crystal phases and the shapes of the products were characterized by XRD and SEM. The results revealed that the composites are spherical with the diameter of 200-300 nm. Magnetic measurements showed that the mixed microspheres exhibit a typical ferromagnetic behavior, a specific saturation magnetization of 56 emu/g and an intrinsic coercivity of 38 Oe at room temperature. The strain of E. coli was used to evaluate the antibacterial activity of the Ag-doped γ-Fe2O3 composites which exhibited very high inhibition.

We present the constraints on the Quintessence scalar field model from the observational data of the variation of the fine structure constant obtained from Keck and VLT telescopes. Within the theoretical frame proposed by Bekenstein, the constraints on the parameters of the Quintessence scalar field model are obtained. By the consideration of the prior of $\Omega_{m0}$ as WMAP 7 suggests, we obtain various results of the different samples. Based on these results, we also calculate the probability density function of the coupling constant $\zeta$. The best-fit values show a consistent relationship between $\zeta$ and the different experimental results. In our work, we test two different potential models, namely, the inverse power law potential and the exponential potential. The results show that both the large value of the parameters in the potential and the strong coupling can cause the variation of fine structure constant., Comment: 17 pages, 10 figures, 1 table. Joint constraints added, a few comments added. Accepted for publication in RAA. Updated to match the accepted version

Using the Heisenberg uncertainty principle, Bekenstein once claimed that the horizon area of a black hole is quantized with uniform spacing $8\pi l_{p}^{2}$ . This spacing is shown to be corrected with inverse area terms from the perspective of periodicity, which indicates that the area spectrum in this case is no longer evenly spaced. Concretely we study the corrected area spectrum by equaling the motion period of an outgoing wave to the period of gravitational system in Kruskal coordinate with respect to the Euclidean time with consideration of quantum corrections to the semiclassical action. To check our result, we also study the corrected area spectrum in the framework of Generalized Uncertainty Principle. We find the area spectrum produced from the perspective of periodicity takes the same form as the one obtained by the Generalized Uncertainty Principle. As examples, area spectrum with quantum corrections of a Schwarzschild black hole and a Kerr black hole are studied. Our result shows that the formula for area spectrum with quantum corrections is universal though it is not independent of the black hole parameters. In addition, we also discuss the motion period of fermions and find that the area spectrum of a black hole is independent of particle statistics when the black hole is perturbed by an outgoing fermion.

Layered manganese oxide nanostructures were synthesized by a facile hydrothermal method, using KMnO4 and CH3CH2OH as the precursors. The structure, composition and morphology of the product are evaluated by means of X-ray diffraction (XRD), scanning electron microscopy (SEM) and Infrared (IR) techniques. The results showed that crystalline birnessite-based manganese oxide was formed and the hydrothermal time and temperature had great influence on nanostructures of the products. The electrochemical results showed that birnessite nanowires exhibit excellent cyclic stability performance in the potential application window of 1.5~4.8 V.

The current business application integrated tools only support system level’s integration and management, but this approach doesn’t support application level’s integration and management. For this shortage, we develop an Enterprise Service Bus (ESB) based management tools of application service, which is oriented on power grid business. The tools can manage ESB objects, workflow objects and monitoring objects by combining graphic technology and workflow engineering, so it enhance ESB with more business flexibility. Experiment results prove that the tools are useful in business integration for power grid enterprise.

An approach of fault diagnosis of bearing based on empirical mode decomposition (EMD), sample entropy and 1.5 dimension spectrum was presented. Firstly, the original vibration signal was decomposed into a number of intrinsic mode functions (IMFs) using EMD. Second, the sample entropies of IMFs were calculated to select the sensitive IMF. Finally, the IMF containing fault infor- mation was analyzed with 1.5 dimension spectrum, The experimental results show the method can be used to effectively diagnose faults of rolling bearing.

Wind turbine gearbox is subjected to different sorts of failures, which lead to the increasement of the cost. A approach to fault diagnosis of wind turbine gearbox based on empirical mode decomposition (EMD) and teager kaiser energy operator (TKEO) is presented. Firstly, the original vibration signal is decomposed into a number of intrinsic mode functions (IMFs) using EMD. Then the IMF containing fault information is analyzed with TKEO, The experimental results show that EMD and TKEO can be used to effectively diagnose faults of wind turbine gearbox.

With the non-local observables such as two point correlation function and holographic entanglement entropy, we probe the phase structure of the Born-Infeld-anti-de Sitter black holes. We find for the case $bQ>0.5$, the phase structure is similar to that of the Reissner-Nordstr��m-AdS black hole, namely the black hole undergoes a Hawking-Page phase transition, a first order phase transition, and a second order phase transition. While for the case $bQ, 20 pages, many figures. arXiv admin note: text overlap with arXiv:1512.08855

This paper presents a time Petri net model with the optimizing mechanism based on ant colony systems that addresses the problem of schedule optimization. The choice rules and pheromone update rules of artificial ants are embedded into the evolution rules of a time Petri net, so the modeling and scheduling analysis of real systems can be integrated into the same model. Compared with the approaches based on the heuristic search and genetic algorithms, our method efficiently unifies the modeling and analysis of schedule problems based on a time Petri net.

Nickel ferrite (NiFe2O4) nanoparticles have been synthesized by modified Pechini method in the presence of surfactant and certain amount of concentrated nitric acid. The obtained foamed gel precursors were characterized by thermogravimetry-differential thermal analysis (TG-DTA) to determine the thermal decomposition and subsequently calcined at different temperatures in the range of 500--800°C for 2 h to obtain NiFe2O4 nanoparticles, which were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), transmission electron micrograph (TEM), and vibrating sample magnetometer (VSM). The results showed that Ni ferrite nanoparticles obtained by modified Pechini method exhibited good dispersibility, uniform distribution, and good crystallinity, and the particle diameter of NiFe2O4 calcined at 500°C is almost 80 nm. Its saturation magnetization was 50.5 emu/g at the maximum magnetic field of 10 kOe at room temperature. The particle size, saturation magnetization, and coercivity o...

The paper analyzed on failure mechanism of key components (blades, gearboxes) of wind turbine. Then, that introduced the development about the methods of condition monitoring of the key components. It also described that in recent years the development of methods with location of fault, fault diagnosis and failure distribution respectively. According to the present problems of condition monitoring of wind turbine, the text summed up the problems in four aspects for the future: research of the fault mechanism and failure criterion, vibration signal processing and the method of feature extraction research, study on coupling of wind turbine system, development of on-line monitoring systems.

Using classical time-average approximation, critical temperature and condensed solution in holographic p-wave superconductors with a time-dependent source is investigated in probe limit. By choosing suitable gauge field ansatz, the equation of motion for a vector field is presented. With the help of the Sturm—Liouville equation, concrete values of phase transition temperature and critical frequency are obtained. It is shown that the phase transition temperature enhances as the frequency of the time-dependent source raises in high frequency regime, which means that the operators on the boundary field theory will be easier to condense.

CeO 2 nanostructures were successfully prepared by a facile and environmentally friendly mixed-solvothermal method under mild conditions. The X-ray diffraction (XRD) and transmission electron microscope (TEM) results indicated that the as-synthesized products were cubic CeO 2 polycrystalline structures with uniform diameters in the range of 10–20 nm and lengths up to 80 nm. X-ray photoelectron spectroscopy (XPS) spectra and EDX data demonstrated that stoichiometric CeO 2 was formed. A possible growth mechanism of the CeO 2 nanostructures was proposed. Moreover, ultraviolet absorption measurement revealed the band gap of the CeO 2 nanorods was estimated to be 3.85 eV, which is larger than the reported value for the bulk CeO 2 ( E g =3.2 eV). Enhancement of the band gap of the CeO 2 nanorods is attributed to the well-known quantum size effect.

Layered LiNi1/3Co1/3Mn1/3O2 nanoparticles were prepared by modified Pechini method and used as cathode materials for Li-ion batteries. The pyrolytic behaviors of the foamed precursors were analyzed by use of simultaneous thermogravimetric and differential thermal analysis (TG-DTA). Structure, morphology and electrochemical performance characterization of the samples were investigated by X-ray diffraction (XRD), field emission scanning electron macroscopy(SEM), Brunauer-Emmett-Teller (BET) specific surface area and charge–discharge tests. The results showed that the samples prepared by modified Pechini method caclined at 900 °C for 10 h were indexed to pure LiNi1/3Co1/3Mn1/3O2 with well hexagonal structure. The particle size was in a range of 100–300 nm. The specific surface area was larger than that of the as-obtained sample by Pechini method. Initial discharge capacity of 163.8 mAh/g in the range 2.8–4.4 V (vs. Li/Li+) and at 0.1C for LiNi1/3Co1/3Mn1/3O2 prepared by modified Pechini method was obtained, higher than that of the sample prepared by Pechini method (143.5 mAh/g). Moreover, the comparison of electrochemical results at different current rates indicated that the sample prepared by modified Pechini method exhibited improved rate capability.

NiO/Ni nanocomposites were prepared by chemically reduction-oxidation process in tetra-ethylene glycol (TEG) solution. The structure and morphology of the samples were examined by XRD and SEM. The results indicated the composite consisted of NiO and Ni and exhibited spherical morphology with diameter of 50-200 nm. The electrochemical performances of composite electrodes used in electrochemical capacitors were studied. The electrochemical measurements were carried out using cyclic voltammetry, galvanostatic charge/discharge and impedance spectroscopy in 6M KOH aqueous electrolyte using three-electrode Swagelok systems. The results showed that the composite had a high specific capacitance and excellent capacitive behavior. The specific capacitance of the composite decreased to 192F/g after 500 cycles. Due to the existance of Ni, the charge transfer resistance is lower than 1Ω. It revealed that the composite exhibited good cycling performance.

After Hawking radiation from a Schwarzschild black hole is calculated using the Damour–Ruffini method, the tortoise coordinate transformation in a static black hole is extended to a dynamical axisymmetric black hole, such as a dynamical Kerr–Newman black hole. Under the generalized tortoise coordinate transformation, Hawking radiation from a dynamical Kerr–Newman black hole is obtained successfully. Moreover, it also seems to occur on the apparent horizon instead of the event horizon.