1. Encephalic meningioangiomatosis in a dog with high-grade undefined glioma.
- Author
-
Silveira BO, de Melo SMP, Cony FG, Serena GC, Pereira VC, de Castro LT, Wodzik VS, Bandinelli MB, Panziera W, and Pavarini SP
- Subjects
- Humans, Male, Dogs, Animals, Spinal Cord pathology, Brazil, Glioma veterinary, Dog Diseases pathology
- Abstract
Meningioangiomatosis (MA) is a rare proliferative meningovascular disorder that affects mainly the cerebral cortex, brainstem and spinal cord of humans and animals and can coexist with other proliferative disorders. A 7.5-year-old male Brazilian Campeiro Bulldog died after a convulsive crisis and cardiorespiratory arrest. At necropsy, a firm, white mass involving the piriform and right occipital lobes was seen. Histologically, the mass consisted of two morphologically distinct entities that collided: a congenital malformation characterized by a proliferation of meningothelial cells around blood vessels, within the perivascular spaces; and a neoplasm composed of two cell populations with astrocytic and oligodendrocytic differentiation. Meningothelial cells and neoplastic glial cells immunolabelled for vimentin. This first reported case of encephalic MA with a high-grade undefined glioma in a dog was confirmed through clinical signs, pathological and immunohistochemical findings., (Copyright © 2023 Elsevier Ltd. All rights reserved.)
- Published
- 2023
- Full Text
- View/download PDF