43 results on '"Wittwer, Arthur J."'
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2. The advantages of describing covalent inhibitor in vitro potencies by IC50 at a fixed time point. IC50 determination of covalent inhibitors provides meaningful data to medicinal chemistry for SAR optimization
3. Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis
4. Kinetic and structural characterization of caspase-3 and caspase-8 inhibition by a novel class of irreversible inhibitors
5. Identification of Folate Binding Protein of Mitochondria as Dimethylglycine Dehydrogenase
6. Distribution of Two Selenonucleosides among the Selenium-Containing tRNAs from Methanococcus vannielii
7. Substrate-dependent inhibition kinetics of an active site-directed inhibitor of ADAMTS-4 (aggrecanase 1)
8. Three-dimensional structure of human cytomegalovirus protease
9. Chemokine gene expression in anti-glomerular basement membrane antibody glomerulonephritis
10. Deciphering the Allosteric Binding Mechanism of the Human Tropomyosin Receptor Kinase A (hTrkA) Inhibitors
11. Examination of the kinetic mechanism of mitogen-activated protein kinase activated protein kinase-2
12. Three-dimensional structure of human cytomegalovirus protease
13. Intraocular production of a cytokine (CINC) responsible for neutrophil infiltration in endotoxin induced uveitis
14. Cytokine-induced Neutrophil Chemoattractant Mediates Neutrophil Influx in Immune Complex Glomerulonephritis in Rat
15. Aminopyrazole Carboxamide Bruton’s Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning
16. Imidazo[1,5- a]quinoxalines as irreversible BTK inhibitors for the treatment of rheumatoid arthritis
17. Selenium-Containing Transfer RNAs
18. Discovery of (pyridin-4-yl)-2 H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis
19. Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1
20. High-performance liquid chromatography–tandem mass spectrometry assay of fatty acid amide hydrolase (FAAH) in blood: FAAH inhibition as clinical biomarker
21. Expression, purification, and characterization of TYK-2 kinase domain, a member of the Janus kinase family
22. Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis
23. Structural and Inhibition Analysis Reveals the Mechanism of Selectivity of a Series of Aggrecanase Inhibitors
24. α2-Macroglobulin Is a Novel Substrate for ADAMTS-4 and ADAMTS-5 and Represents an Endogenous Inhibitor of These Enzymes
25. Recombinant full-length human cytomegalovirus protease has lower activity than recombinant processed protease domain in purified enzyme and cell-based assays
26. Inhibition of human cytomegalovirus protease by benzoxazinones and evidence of antiviral activity in cell culture
27. Addendum
28. High-level expression of cytokine-induced neutrophil chemoattractant (CINC) by a metastatic rat cell line: Purification and production of blocking antibodies
29. Oligosaccharides at each glycosylation site make structure-dependent contributions to biological properties of human tissue plasminogen activator
30. Secretion of active kringle-2-serine protease in Escherichia coli
31. Large-Scale Purification of Tissue-Type Plasminogen Activator from Cultured Human Cells.
32. Nutrient density—Evaluation of nutritional attributes of foods
33. Determination of the number of endothelial cells in culture using an acid phosphatase assay
34. An Index of Nutritional Quality for a balanced diet
35. Effects of N-glycosylation on in vitro activity of Bowes melanoma and human colon fibroblast-derived tissue plasminogen activator
36. Cell-type-specific and site-specific N-glycosylation of type I and type II human tissue plasminogen activator
37. Identification and synthesis of a naturally occurring selenonucleoside in bacterial tRNAs: 5-[(methylamino)methyl]-2-selenouridine
38. Biosynthesis of 5-methylaminomethyl-2-selenouridine, a naturally occurring nucleoside in Escherichia coli tRNA
39. Purification and characterization of a tissue plasminogen activator-inhibitor complex from human umbilical vein endothelial cell conditioned medium
40. An Index of Nutritional Quality for a balanced diet. New help for anold problem
41. α2-Macroglobulin Is a Novel Substrate for ADAMTS-4 and ADAMTS-5 and Represents an Endogenous Inhibitor of These Enzymes.
42. Differential kinetics and inhibition of purified recombinant tyrosine kinase 2 (TYK-2) and its catalytic domain JH-1.
43. Alpha2-macroglobulin is a novel substrate for ADAMTS-4 and ADAMTS-5 and represents an endogenous inhibitor of these enzymes.
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