48 results on '"Wendeler, Michaela"'
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2. Using multimodal chromatography for post-conjugation antibody-drug conjugate purification: A methodology from high throughput screening to in-silico process development
3. Kinetic models towards an enhanced understanding of diverse ADC conjugation reactions.
4. Monitoring of antibody-drug conjugation reactions with UV/Vis spectroscopy
5. Multi-step high-throughput conjugation platform for the development of antibody-drug conjugates
6. Corrigendum: Kinetic studies and CFD-based reaction modeling for insights into the scalability of ADC conjugation reactions
7. Impact of Magnetic Stirring on Stainless Steel Integrity: Effect on Biopharmaceutical Processing
8. Kinetic studies and CFD-based reaction modeling for insights into the scalability of ADC conjugation reactions
9. Rational Downstream Development for Aav Full/Empty Capsid Separation – a Streamlined Methodology Based on High-Throughput Screening and Mechanistic Modeling
10. Process-scale purification and analytical characterization of highly gamma-carboxylated recombinant human prothrombin
11. Human Immunodeficiency Virus Reverse Transcriptase
12. Development and scale-up of a commercial fed batch refolding process for an anti-CD22 two chain immunotoxin
13. Hexosaminidase assays
14. Characterization of human saposins by NMR spectroscopy
15. Interaction of the GM2 Activator Protein with Sulfated and Sialylated Glycosphingolipids
16. Recombinant Ganglioside GM2 Synthase—Expression in Insect Cells and Enzyme Assay
17. Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein
18. The enzyme-binding region of human GM2-activator protein
19. Combination of CP/MAS NMR spectroscopy and X-ray crystallography: Structure and Dynamics in molecular crystals of hydrogen, lithium, sodium, rubidium, and cesium penicillin V
20. Synthesis of novel NBD-GM1 and NBD-GM2 for the transfer activity of GM2-activator protein by a FRET-based assay system
21. Photoaffinity labelling of the Human GM2-activator protein: Mechanistic insight into ganglioside GM2 degradation
22. Site-specific antibody-drug conjugate heterogeneity characterization and heterogeneity root cause analysis
23. Evaluation of continuous nonaffinity capture chromatography for a recombinant enzyme—optimization for a changing perfusion feedstream and comparison to batch processing
24. Characterizing the Overall Derivatization of Conjugated Oligomeric Proteins
25. A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties
26. Camelid VHH affinity ligands enable separation of closely related biopharmaceuticals
27. Camelid VHH affinity ligands enable separation of closely related biopharmaceuticals.
28. Enhanced Catalysis of Oxime-Based Bioconjugations by Substituted Anilines
29. Correlating SHAPE signatures with three-dimensional RNA structures
30. Structure-Activity Analysis of Vinylogous Urea Inhibitors of Human Immunodeficiency Virus-Encoded Ribonuclease H
31. HIV-1 Reverse Transcriptase Can Simultaneously Engage Its DNA/RNA Substrate at Both DNA Polymerase and RNase H Active Sites: Implications for RNase H Inhibition
32. HIV ribonuclease H: continuing the search for small molecule antagonists
33. Vinylogous Ureas as a Novel Class of Inhibitors of Reverse Transcriptase-Associated Ribonuclease H Activity
34. Hexosaminidase assays
35. Mapping interactions of HIV‐1 Reverse Transcriptase with ligands by Protein Footprinting using chemical proteases
36. Nucleotide Excision Repair and Template-independent Addition by HIV-1 Reverse Transcriptase in the Presence of Nucleocapsid Protein
37. Expression of the GM2-activator protein in the methylotrophic yeast Pichia pastoris, purification, isotopic labeling, and biophysical characterization
38. Inhibitors of Endocannabinoid Degradation: Potential Therapeutics for Neurological Disorders
39. Inhibitoren des Endocannabinoid‐Abbaus: potenzielle Therapeutika neurologischer Störungen
40. Chemical Chaperones — A New Concept in Drug Research
41. Expression of recombinant human GM2-activator protein in insect cells: purification and characterization by mass spectrometry
42. Pathology of Glycosphingolipid Metabolism: The Molecular and Cellular Basis of Neurodegenerative Disease
43. Enhanced Catalysis of Oxime-Based Bioconjugationsby Substituted Anilines.
44. Wissenschaft aktuell
45. Inhibitors of Endocannabinoid Degradation: Potential Therapeutics for Neurological Disorders
46. Camelid V H H affinity ligands enable separation of closely related biopharmaceuticals.
47. Enhanced catalysis of oxime-based bioconjugations by substituted anilines.
48. Inhibitors of endocannabinoid degradation: potential therapeutics for neurological disorders.
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