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1. Maternal plasma human immunodeficiency virus type I RNA level: a determinant and projected threshold for mother-to-child transmission

Author

Fang, Guowei, Burger, Harold, Grimson, Roger, Tropper, Pamela, Nachman, Sharon, Mayers, Douglas, Weislow, Owen, Moore, Rosalyn, Reyelt, Christine, Hutcheon, Nancy, Baker, David, and Weisler, Barbara

Subjects
HIV infection -- Physiological aspects, HIV patients -- Physiological aspects, Science and technology
Abstract

The role of maternal plasma HIV-1 RNA levels in mother-to-child transmission was assessed by measuring HIV-1 RNA in 30 HIV positive women and their infants by quantitative competitive-polymerase chain reaction. The results revealed a high correlation between maternal plasma HIV-1 RNA and the percentage of mother-to-child transmission of the disease. This study is expected to provide insight to predicting the risk of transmission of HIV-1 from mothers to their children.

Published
1995

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