Maternal plasma human immunodeficiency virus type I RNA level: a determinant and projected threshold for mother-to-child transmission

Authors :: Fang, Guowei
Burger, Harold
Grimson, Roger
Tropper, Pamela
Nachman, Sharon
Mayers, Douglas
Weislow, Owen
Moore, Rosalyn
Reyelt, Christine
Hutcheon, Nancy
Baker, David
Weisler, Barbara
Source :: Proceedings of the National Academy of Sciences of the United States. Dec 19, 1995, Vol. 92 Issue 26, p12100, 5 p.
Publication Year :: 1995
Abstract: The role of maternal plasma HIV-1 RNA levels in mother-to-child transmission was assessed by measuring HIV-1 RNA in 30 HIV positive women and their infants by quantitative competitive-polymerase chain reaction. The results revealed a high correlation between maternal plasma HIV-1 RNA and the percentage of mother-to-child transmission of the disease. This study is expected to provide insight to predicting the risk of transmission of HIV-1 from mothers to their children.

Subjects :: HIV infection -- Physiological aspects
HIV patients -- Physiological aspects
Science and technology

ISSN :: 00278424
Volume :: 92
Issue :: 26
Database :: Gale General OneFile
Journal :: Proceedings of the National Academy of Sciences of the United States
Publication Type :: Academic Journal
Accession number :: edsgcl.18090751

Tools