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Enantioselective Ni‐catalyzed C(sp3)−H bond activation remains an elusive challenge. Herein, we used phosphine oxide‐ligated Ni−Al bimetallic catalyst to realize enantioselective Ni‐catalyzed aliphatic C(sp3)−H activation of formamides, providing a series of chiral N‐containing heterocycles in 40–95 % yield and 70–95 % ee. [ABSTRACT FROM AUTHOR]

Using NECP/NCAR monthly average data and 216 months average monthly precipitation data of the University of Delaware during 1982-1999. Analyzed the precipitation vapour transport process affects precipitation in the Pearl River Basin in different seasons. On this basis, the seasonal differences NDVI changes in climate-driven factors in the Pearl River Basin.

We study the incompressible magneto-micropolar fluid equations with partial viscosity in . A blow-up criterion of smooth solutions is obtained. The result is analogous to the celebrated Beale-Kato-Majda type criterion for the inviscid Euler equations of incompressible fluids.

Due to the lack of proper chiral ligands, enantioselective C(sp2)–H borylation has been a challenging goal for a long time. Recently, three different types of well‐designed chiral ligands were developed, not only addressing this challenge, but also providing a good inspiration for the future development of other asymmetric reactions. [ABSTRACT FROM AUTHOR]

Due to the lack of proper chiral ligands, enantioselective C(sp2)–H borylation has been a challenging goal for a long time. Recently, three different types of well‐designed chiral ligands were developed, not only addressing this challenge, but also providing a good inspiration for the future development of other asymmetric reactions. [ABSTRACT FROM AUTHOR]

In this paper, we investigate the Cauchy problem for the three-dimensional nematic liquid crystal flows with partial viscosity, and a blow up criterion of smooth solutions is established. This result is analogous to the celebrated Beale-Kato-Majda breakdown criterion for the incompressible Euler equations. Copyright © 2012 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

Enantioselective Ni-catalyzed C(sp 3 )-H bond activation remains an elusive challenge. Herein, we used phosphine oxide-ligated Ni-Al bimetallic catalyst to realize enantioselective Ni-catalyzed aliphatic C(sp 3 )-H activation of formamides, providing a series of chiral N-containing heterocycles in 40-95 % yield and 70-95 % ee., (© 2022 Wiley-VCH GmbH.)

Twofold C-H annulation of readily available formamides and alkynes without built-in chelating groups was achieved. Ni-Al bimetallic catalysis enabled by a bulky BINOL-derived chiral secondary phosphine oxide (SPO) ligand proved to be critical for high reactivity and high selectivity. This reaction uses readily available formamides as starting materials and provides a concise synthetic pathway to a broad range of chiral ferrocenes in 40-98 % yield and 93-99 % ee., (© 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)

An ortho-selective rhodium-catalyzed direct C-H arylation of 1,1'-bi-2-naphthol (BINOL), to deliver the widely used but not easily available 3,3'-diaryl BINOL, has been developed. This highly efficient one-step synthetic approach is the shortest route to date and is greatly facilitated by the newly developed ligand system comprising tBu 2 PCl, Ph 2 -cod, and Cy 3 P⋅HBF 4 . In addition, the same procedure can facilitate the challenging syntheses of 3-bulkyaryl BINOLs in good to excellent yields., (© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)

An FeBr3 -catalyzed reductive coupling of various aldehydes with alkenes that proceeds through a direct hydride transfer pathway has been developed. With (i) PrOH as the hydrogen donor under mild conditions, previously challenging coupling reactions of unactivated alkyl and aryl aldehydes with simple alkenes, such as styrene derivatives and α-olefins, proceeded smoothly to furnish a diverse range of functionalized alcohols with complete linear regioselectivity., (© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Objective: To observe the effect of amylin on the islet beta-cells voltage-gated L-calcium channels in rats., Method: Patch clamp technique was employed in the observation of the features and changes of electric current of islet beta-cells voltage-gated L-calcium channels before and after using amylin., Results: In the glucose environment of 5.5 mmol/L, the electric current of rat islet beta-cells voltage-gated L-calcium channels was activated at -40 mV and reached the peak at about +20 mV, with a peak value of about -120 pA and the insulin secretion level was (0.76 +/- 0.12) microg/L. Under the stimulation of glucose of 16.7 mmol/L, the peak current voltage moved to the left and increased up to - 140 pA and the level of insulin secretion measured (1.78 +/- 0.13) microg/L. Hatch islet beta-cells in amylin at the concentrations of 0.5, 1.0, 5.0 and 10.0 micromol/L, respectively. It was observed that in the 0.5 micromol/L and 1.0 micromol/L groups, there was no remarkable change in the peak potential activation voltage, current, and insulin secretion volume in comparison with the control group. However, in the environment of 5.5 mmol/L glucose, the increase of activation voltage of the 5.0 and 10.0 micromol/L groups was - 30 mV, with the peak current reduced to approximately -80 pA and -60 pA and the insulin secretion decreased to (0.49 +/- 0.11) microg/L and (0.36 +/- 0.12) microg/L respectively. Under the concentration of 16.7 mmol/L glucose, the activation voltage increased from -40 mV up to -30 mV and the peak current reduced to -80 pA and -40 pA. In the meantime, the insulin secretion decreased respectively to (1.20 +/- 0.13) microg/L and (0.89 +/- 0.14) microg/L, which is of significance., Conclusion: The secretion of insulin is synchronized with the opening of the islet beta-cells voltage-gated L-calcium channels at the stimulation of glucose. The amylin inhibition of the insulin secretion is also synchronized with the opening of islet beta-cells voltage-gated L-calcium channels and it's in a positive concentration-dependent manner.