Back to Search
Start Over
Enantioselective Nickel‐Catalyzed C(sp3)−H Activation of Formamides.
- Source :
-
Angewandte Chemie International Edition . 10/17/2022, Vol. 61 Issue 42, p1-5. 5p. - Publication Year :
- 2022
-
Abstract
- Enantioselective Ni‐catalyzed C(sp3)−H bond activation remains an elusive challenge. Herein, we used phosphine oxide‐ligated Ni−Al bimetallic catalyst to realize enantioselective Ni‐catalyzed aliphatic C(sp3)−H activation of formamides, providing a series of chiral N‐containing heterocycles in 40–95 % yield and 70–95 % ee. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14337851
- Volume :
- 61
- Issue :
- 42
- Database :
- Academic Search Index
- Journal :
- Angewandte Chemie International Edition
- Publication Type :
- Academic Journal
- Accession number :
- 159630019
- Full Text :
- https://doi.org/10.1002/anie.202209625