1. Near real-rime MRI of interstitial laser photocoagulation ofin vivo rat liver
- Author
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Sg Bown, M Clemence, WR Lees, G. Buonaccorsi, Margaret A Hall-Craggs, H. R. S. Roberts, and M. Paley
- Subjects
Laser surgery ,Materials science ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,Biological reaction ,medicine.medical_treatment ,Biophysics ,Mri compatible ,Interstitial laser ,Magnetic resonance imaging ,Similar time ,Nuclear magnetic resonance ,Rat liver ,medicine ,Radiology, Nuclear Medicine and imaging ,Temperature mapping ,Biomedical engineering - Abstract
Magnetic resonance imaging (MRI) is showing considerable promise as a monitor for interventional procedures. Laser surgery is “MRI compatible, ” and temperature-sensitive imaging techniques can be usefully applied to these procedures. We have been investigatingT1derived temperature-dependent imaging as a monitor for interstitial laser photocoagulation (ILP) in rat liver.In vitro experiments suggested that temperature calibration may be achieved. We have investigated ILPin vivo using short TR spin-echo imaging sequences taking one set of images every 30 s during and after the procedure. Our resultsin vivo suggest that this simple model may be inadequate for temperature mapping as the biological reaction to the ILP is on a similar time scale to that of the procedure. Nonetheless, MRI shows well-defined, repeatable signal changes that can be related to histological borders.
- Published
- 1994