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129 results on '"Vom Dahl, Juergen"'

1. Use and effectiveness of remdesivir for the treatment of patients with covid-19 using data from the Lean European Open Survey on SARS-CoV-2 infected patients (LEOSS): a multicentre cohort study

Author

Pilgram, Lisa, Appel, Katharina S., Ruethrich, Maria M., Koll, Carolin E. M., Vehreschild, Maria J. G. T., de Miranda, Susana M. Nunes, Hower, Martin, Hellwig, Kerstin, Hanses, Frank, Wille, Kai, Haselberger, Martina, Spinner, Christoph D., Vom Dahl, Juergen, Hertenstein, Bernd, Westhoff, Timm, Vehreschild, J. Janne, Jensen, Björn-Erik Ole, and Stecher, Melanie

Published
2023
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2. Guideline adherence in the use of coronary angiography in patients presenting at the emergency department without myocardial infarction – Results from the German ENLIGHT-KHK project

Author

Wein, Bastian, Seleznova, Yana, Mueller, Dirk, Naumann, Marie, Loeser, Simon, Steffen, Melanie, Windhoevel, Ute, Haude, Michael, vom Dahl, Juergen, Schaefer, Ulrich, Montenbruck, Moritz, Jegodka, Ruediger, Dill, Thorsten, Guelker, Jan-Erik, Boese, Dirk, Bogs, Björn, Harmel, Eva, and Bruder, Oliver

Published
2023
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3. NT-proBNP Response to Sacubitril/Valsartan in Hospitalized Heart Failure Patients With Reduced Ejection Fraction: TRANSITION Study

Author

Gniot, Jacek, Mozheiko, Maria, Lelonek, Malgorzata, Dominguez, Antonio Reyes, Horacek, Thomas, Garcia del Rio, Enrique, Kobalava, Zhanna, Mueller, Christian Eugen, Cavusoglu, Yuksel, Straburzynska-Migaj, Ewa, Slanina, Miroslav, vom Dahl, Juergen, Senni, Michele, Ryding, Alisdair, Moriarty, Andrew, Robles, Manuel Beltran, Villota, Julio Nunez, Quintana, Antonio Garcia, Nitschke, Thorsten, Garcia Pinilla, Jose Manuel, Bonet, Luis Almenar, Chaaban, Said, Filali zaatari, Samia, Spinar, Jindrich, Musial, Wlodzimierz, Abdelbaki, Khaled, Belohlavek, Jan, Fehske, Wolfgang, Bott, Michael Carlos, Hoegalmen, Geir, Leiro, Marisa Crespo, Ozcan, Ismail Turkay, Mullens, Wilfried, Kryza, Radim, Al-Ani, Riadh, Loboz-Grudzien, Krystyna, Ermoshkina, Lyudmila, Hojerova, Silvia, Fernandez, Alberto Alfredo, Spinarova, Lenka, Lapp, Harald, Bulut, Efraim, Almeida, Filipa, Vishnevsky, Alexander, Belicova, Margita, Pascual, Domingo, Witte, Klaus, Wong, Kenneth, Droogne, Walter, Delforge, Marc, Peterka, Martin, Olbrich, Hans-Georg, Carugo, Stefano, Nessler, Jadwiga, McGill, Thao Huynh, Huegl, Burkhard, Akin, Ibrahim, Moreira, Ilidio, Baglikov, Andrey, Thambyrajah, Jeetendra, Hayes, Chris, Barrionuevo, Marcelo Raul, Yigit, Zerrin, Kaya, Hakki, Klimsa, Zdenek, Radvan, Martin, Kadel, Christoph, Landmesser, Ulf, Di Tano, Giuseppe, Lisik, Malgorzata Buksinska, Fonseca, Candida, Oliveira, Luis, Marques, Irene, Santos, Luis Miguel, Lenner, Egon, Letavay, Peter, Bueno, Manuel Gomez, Mota, Paula, Wong, Aaron, Bailey, Kristian, Foley, Paul, Hasbani, Eduardo, Virani, Sean, Massih, Tony Abdel, Al-Saif, Shukri, Taborsky, Milos, Kaislerova, Marta, Motovska, Zuzana, Cohen, Aron Ariel, Logeart, Damien, Endemann, Dierk, Ferreira, Daniel, Brito, Dulce, Kycina, Peter, Bollano, Entela, Basilio, Enrique Galve, Rubio, Lorenzo Facila, Aguado, Marcos Garcia, Schiavi, Lilia Beatriz, Zivano, Daniel Francisco, Lonn, Eva, El Sayed, Ali, Pouleur, Anne-Catherine, Heyse, Alex, Schee, Alexandr, Polasek, Rostislav, Houra, Marek, Tribouilloy, Christophe, Seronde, Marie France, Galinier, Michel, Noutsias, Michel, Schwimmbeck, Peter, Voigt, Ingo, Westermann, Dirk, Pulignano, Giovanni, Vegsundvaag, Johnny, Da Silva Antunes, Jose Alexandre, Monteiro, Pedro, Stevlik, Jan, Goncalvesova, Eva, Hulkoova, Beata, Castro Fernandez, Antonio Juan, Davies, Ceri, Squire, Iain, Meyer, Philippe, Sheppard, Richard, Sahin, Tayfun, Sochor, Karel, De Geeter, Guillaume, Wachter, Rolf, Schmeisser, Alexander, Weil, Joachim, Soares, Ana Oliveira, Vasilevna, Olga Bulashova, Oshurkov, Andrey, Sunderland, Shahid Junejo, Glover, Jason, Exequiel, Tomas, Decoulx, Eric, Meyer, Sven, Muenzel, Thomas, Frioes, Fernando, Arbolishvili, Georgy, Tokarcikova, Anna, Karlstrom, Patric, Trullas Vila, Joan Carles, Perez, Gonzalo Pena, Sankaranarayanan, Rajiv, Nageh, Thuraia, Alasia, Diego Cristian, Refaat, Marwan, Demirkan, Burcu, Al-Buraiki, Jehad, Karabsheh, Shadi, Pascual-Figal, Domingo, Bao, Weibin, Noè, Adele, Schwende, Heike, Butylin, Dmytro, and Prescott, Margaret F.

Published
2020
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4. Evaluation of the guideline-adherence of coronary angiography in patients with suspected chronic coronary syndrome – Results from the German prospective multicentre ENLIGHT-KHK project

Author

Wein, Bastian, primary, Seleznova, Yana, additional, Mueller, Dirk, additional, Naumann, Marie, additional, Loeser, Simon, additional, Artmann, Joerg, additional, Fritz, Thomas, additional, Steffen, Melanie, additional, Windhoevel, Ute, additional, Haude, Michael, additional, vom Dahl, Juergen, additional, Schaefer, Ulrich, additional, Montenbruck, Moritz, additional, Zarse, Markus, additional, Jegodka, Ruediger, additional, Dill, Thorsten, additional, Guelker, Jan-Erik, additional, Boese, Dirk, additional, and Bruder, Oliver, additional

Published
2023
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6. Covid-19 triage in the emergency department 2.0: how analytics and AI transform a human-made algorithm for the prediction of clinical pathways

Author

Bartenschlager, Christina C., Grieger, Milena, Erber, Johanna, Neidel, Tobias, Borgmann, Stefan, Vehreschild, Jörg J., Steinbrecher, Markus, Rieg, Siegbert, Stecher, Melanie, Dhillon, Christine, Ruethrich, Maria M., Jakob, Carolin E. M., Hower, Martin, Heller, Axel R., Vehreschild, Maria, Wyen, Christoph, Messmann, Helmut, Piepel, Christiane, Brunner, Jens O., Hanses, Frank, Römmele, Christoph, Spinner, Christoph, Ruethrich, Maria Madeleine, Lanznaster, Julia, Wille, Kai, Tometten, Lukas, Dolff, Sebastian, von Bergwelt-Baildon, Michael, Merle, Uta, Rothfuss, Katja, Isberner, Nora, Jung, Norma, Göpel, Siri, vom Dahl, Juergen, Degenhardt, Christian, Strauss, Richard, Gruener, Beate, Eberwein, Lukas, Hellwig, Kerstin, Rauschning, Dominic, Neufang, Mark, Westhoff, Timm, Raichle, Claudia, Akova, Murat, Jensen, Bjoern-Erik, Schubert, Joerg, Grunwald, Stephan, Friedrichs, Anette, Trauth, Janina, de With, Katja, Guggemos, Wolfgang, Kielstein, Jan, Heigener, David, Markart, Philipp, Bals, Robert, Stieglitz, Sven, Voigt, Ingo, Taubel, Jorg, and Milovanovic, Milena

Subjects
ddc:610
Abstract

The Covid-19 pandemic has pushed many hospitals to their capacity limits. Therefore, a triage of patients has been discussed controversially primarily through an ethical perspective. The term triage contains many aspects such as urgency of treatment, severity of the disease and pre-existing conditions, access to critical care, or the classification of patients regarding subsequent clinical pathways starting from the emergency department. The determination of the pathways is important not only for patient care, but also for capacity planning in hospitals. We examine the performance of a human-made triage algorithm for clinical pathways which is considered a guideline for emergency departments in Germany based on a large multicenter dataset with over 4,000 European Covid-19 patients from the LEOSS registry. We find an accuracy of 28 percent and approximately 15 percent sensitivity for the ward class. The results serve as a benchmark for our extensions including an additional category of palliative care as a new label, analytics, AI, XAI, and interactive techniques. We find significant potential of analytics and AI in Covid-19 triage regarding accuracy, sensitivity, and other performance metrics whilst our interactive human-AI algorithm shows superior performance with approximately 73 percent accuracy and up to 76 percent sensitivity. The results are independent of the data preparation process regarding the imputation of missing values or grouping of comorbidities. In addition, we find that the consideration of an additional label palliative care does not improve the results.

Published
2023

7. Evaluation of the guideline-adherence of coronary angiography in patients with suspected chronic coronary syndrome – results from the German prospective multicentre ENLIGHT-KHK project

Author

Wein, Bastian, Seleznova, Yana, Mueller, Dirk, Naumann, Marie, Loeser, Simon, Artmann, Joerg, Fritz, Thomas, Steffen, Melanie, Windhoevel, Ute, Haude, Michael, vom Dahl, Juergen, Schaefer, Ulrich, Montenbruck, Moritz, Zarse, Markus, Jegodka, Ruediger, Dill, Thorsten, Guelker, Jan-Erik, Boese, Dirk, and Bruder, Oliver

Subjects
Original Paper, ddc:610, Cardiology and Cardiovascular Medicine
Abstract

BACKGROUND: With 900′000 coronary angiographies (CA) per year, Germany has the highest annual per capita volume in Europe. Until now there are no prospective clinical data on the degree of guideline-adherence in the use of CA in patients with suspected chronic coronary syndrome (CCS) in Germany. METHODS: Between January 2019 and August 2021, 458 patients with suspected CCS were recruited in nine German centres. Guideline-adherence was evaluated according to the current European Society of Cardiology and German guidelines. Pre-test probability (PTP) for CAD was determined using age, gender, and a standardized patient questionnaire to identify symptoms. Data on the diagnostic work-up were obtained from health records. RESULTS: Patients were in mean 66.6 years old, male in 57.3 %, had known CAD in 48.4 % and presented with typical, atypical, non-anginal chest pain or dyspnoea in 35.7 %, 41.3 %, 23.0 % and 25.4 %, respectively. PTP according to the European guidelines was in mean 24.2 % (11.9 %-36.5 % 95 % CI). 20.9 % of the patients received guideline-recommended preceding non-invasive image guided testing. The use of CA was adherent to the European and German guideline recommendations in 20.4 % and 25.4 %, respectively. In multivariate-analysis, arterial hypertension and prior revascularization were predictors of guideline non-adherence. CONCLUSION: These are the first prospective clinical data which demonstrated an overall low degree of guideline-adherence in the use of CA in patients with suspected CCS in the German health care setting. To improve adherence rates, the availability of and access to non-invasive image guided testing needs to be strengthened. (German Clinical Trials Registry DRKS00015638 – Registration Date: 19.02.2019)

Published
2023

8. A Multicenter, Phase 2, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Dose-Finding Trial of the Oral Factor XIa Inhibitor Asundexian to Prevent Adverse Cardiovascular Outcomes After Acute Myocardial Infarction

Author

Rao, Sunil V., primary, Kirsch, Bodo, additional, Bhatt, Deepak L., additional, Budaj, Andrzej, additional, Coppolecchia, Rosa, additional, Eikelboom, John, additional, James, Stefan K., additional, Jones, W. Schuyler, additional, Merkely, Bela, additional, Keller, Lars, additional, Hermanides, Renicus S., additional, Campo, Gianluca, additional, Ferreiro, José Luis, additional, Shibasaki, Taro, additional, Mundl, Hardi, additional, Alexander, John H., additional, Hengstenberg, Christian, additional, Steinwender, Clemens, additional, Alber, Hannes, additional, Steringer-Mascherbauer, Regina, additional, Schober, Andreas, additional, Auer, Johann, additional, Roithinger, Franz Xaver, additional, von Lewinski, Dirk, additional, Moertl, Deddo, additional, Huber, Kurt, additional, Coussement, Patrick, additional, Hoffer, Etienne, additional, Beauloye, Christophe, additional, Janssens, Luc, additional, Vranckx, Pascal, additional, De Raedt, Herbert, additional, Vanassche, Thomas, additional, Vrolix, Matthias, additional, Rokyta, Richard, additional, Parenica, Jiri, additional, Pelouch, Radek, additional, Motovska, Zuzanna, additional, Alan, David, additional, Kettner, Jiri, additional, Polasek, Rostislav, additional, Cermak, Ondrej, additional, Sedlon, Pavel, additional, Hanis, Jiri, additional, Novak, Martin, additional, Belohlavek, Jan, additional, Horacek, Thomas, additional, Leggewie, Stefan, additional, Wenzel, Philip, additional, vom Dahl, Juergen, additional, Sievers, Burkhard, additional, Pulz, Jan, additional, Schellong, Sebastian, additional, Clemmensen, Peter, additional, Muller-Hennessen, Matthias, additional, Rassaf, Tienush, additional, Falukozi, Jozsef, additional, Ruzsa, Zoltan, additional, Tomcsanyi, Janos, additional, Csanadi, Zoltan, additional, Herczeg, Bela, additional, Koszegi, Zsolt, additional, Vorobcsuk, Andras, additional, Kiss, Robert, additional, Baranyai, Csaba, additional, Dezsi, Csaba, additional, Lupkovics, Geza, additional, Rossini, Roberta, additional, Scherillo, Marino, additional, Sergio Saba, Pier, additional, Calogero Campo, Gianluca, additional, Calo, Leonardo, additional, Nassiacos, Daniele, additional, Quadri, Giorgio, additional, Sciahbasi, Alessandro, additional, Silvio Marenzi, Gian Carlo, additional, Reimers, Bernhard, additional, Perna, Gian Piero, additional, Sacca, Salvatore, additional, Fattore, Luciano, additional, Brunelli, Claudio, additional, Picchi, Andrea, additional, Kuramochi, Takehiko, additional, Kondo, Kazuhisa, additional, Aoyama, Takahiko, additional, Kudoh, Takashi, additional, Yamamoto, Tadashi, additional, Takaya, Tomofumi, additional, Mukai, Yasushi, additional, Fukui, Kazuki, additional, Morioka, Nobuyuki, additional, Ando, Kenji, additional, Yamamuro, Atsushi, additional, Morita, Yasuhiro, additional, Koga, Yasuaki, additional, Watanabe, Tetsuya, additional, Sakamoto, Tomohiro, additional, Maebuchi, Daisuke, additional, Takahashi, Akihiko, additional, Yonetsu, Taishi, additional, Kakuta, Tsunekazu, additional, Nishina, Hidetaka, additional, Oemrawsingh, Rohit, additional, Dorman, Reinhart, additional, Oude Ophius, Ton, additional, Prins, Paco, additional, al Windy, N.Y.Y., additional, Zoet-Nugteren, S.K., additional, Hermanides, Rik, additional, van Eck, Martijn, additional, Scherptong, Roderick, additional, Cornel, J.H., additional, Damman, Peter, additional, Bech, Gerhard, additional, Torquay, R., additional, Kietselaer, Bas, additional, Grzelakowski, Pawel, additional, Krzysztof, Dyrbus, additional, Miekus, Pawel, additional, Przybylski, Andrzej, additional, Zarebinski, Maciej, additional, Balsam, Pawel, additional, Szachniewicz, Joanna, additional, Gierlotka, Marek, additional, Tycinska, Agnieszka, additional, Iniguez Romo, Andres, additional, Fernandez Ortiz, Antonio, additional, Carrasquer Cucarella, Anna, additional, Sanmartin Fernandez, Marcelo, additional, Sionis, Alessandro, additional, Bueno Zamora, Hector, additional, Ferreiro Gutierrez, Jose Luis, additional, Almenar, Luis, additional, Ferreira Gonzalez, Ignacio, additional, Pascual Figal, Domingo A., additional, Almendro Delia, Manuel, additional, Jimenez Fernandez, Miriam, additional, Skeppholm, Mika, additional, Zedigh, Crister, additional, Angeras, Oskar, additional, Lauermann, Jorg, additional, Erlinge, David, additional, Gustafsson, Robin, additional, Mooe, Thomas, additional, Utreras, Alejandro, additional, James, Stefan, additional, Grimfjard, Per, additional, Pedrazzini, Giovanni, additional, Mach, Francois, additional, Fournier, Stephane, additional, Haegeli, Laurent, additional, Beer, Jurg H., additional, Leibundgut, Gregor, additional, Kobza, Richard, additional, Kaiser, Christoph, additional, Kunadian, Vijay, additional, Al-Lamee, Rasha, additional, Gorog, Diana, additional, Khan, Sohail, additional, Trevelyan, Jasper, additional, Toor, Iqbal, additional, Smith, James, additional, Purushottam, Bhaskar, additional, Treasure, Charles, additional, Arena, Frank, additional, Vedere, Amarnath, additional, Henderson, David, additional, Gilani, Syed, additional, Jones, Alonzo, additional, Carrillo-Jimenez, Rodolfo, additional, Gillespie, Eve, additional, Marhefka, Gregary, additional, Wang, David, additional, Olson, Charles, additional, Bloom, Stephen, additional, Iftikhar, Faizan, additional, Brabham, David, additional, McGinty, John, additional, Thompson, Charles, additional, Talano, James, additional, Ginete, Wilson, additional, Williams, Marcus, additional, Masud, Ali, additional, Ariani, Mehrdad, additional, Bitar, Fahed, additional, Wang, Thomas, additional, and Samuelson, Bradley, additional

Published
2022
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12. Cardiac Arrhythmias in Survivors of Sudden Cardiac Death Requiring Impella Assist Device Therapy

Author

Abdullah, Khaled Q. A., primary, Roedler, Jana V., additional, vom Dahl, Juergen, additional, Szendey, Istvan, additional, Dimitroulis, Dimitrios, additional, Eckardt, Lars, additional, Topf, Albert, additional, Ohnewein, Bernhard, additional, Fritsch, Lorenz, additional, Föttinger, Fabian, additional, Brandt, Mathias C., additional, Wernly, Bernhard, additional, Motloch, Lukas J., additional, and Larbig, Robert, additional

Published
2021
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13. Impella use in real-world cardiogenic shock patients: Sobering outcomes

Author

Abdullah, Khaled Q. A., primary, Roedler, Jana V., additional, vom Dahl, Juergen, additional, Szendey, Istvan, additional, Haake, Hendrik, additional, Eckardt, Lars, additional, Topf, Albert, additional, Ohnewein, Bernhard, additional, Jirak, Peter, additional, Motloch, Lukas J., additional, Wernly, Bernhard, additional, and Larbig, Robert, additional

Published
2021
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16. NT-proBNP Response to Sacubitril/Valsartan in Hospitalized Heart Failure Patients With Reduced Ejection Fraction

Author

Pascual-Figal, Domingo, primary, Wachter, Rolf, additional, Senni, Michele, additional, Bao, Weibin, additional, Noè, Adele, additional, Schwende, Heike, additional, Butylin, Dmytro, additional, Prescott, Margaret F., additional, Gniot, Jacek, additional, Mozheiko, Maria, additional, Lelonek, Malgorzata, additional, Dominguez, Antonio Reyes, additional, Horacek, Thomas, additional, Garcia del Rio, Enrique, additional, Kobalava, Zhanna, additional, Mueller, Christian Eugen, additional, Cavusoglu, Yuksel, additional, Straburzynska-Migaj, Ewa, additional, Slanina, Miroslav, additional, vom Dahl, Juergen, additional, Ryding, Alisdair, additional, Moriarty, Andrew, additional, Robles, Manuel Beltran, additional, Villota, Julio Nunez, additional, Quintana, Antonio Garcia, additional, Nitschke, Thorsten, additional, Garcia Pinilla, Jose Manuel, additional, Bonet, Luis Almenar, additional, Chaaban, Said, additional, Filali zaatari, Samia, additional, Spinar, Jindrich, additional, Musial, Wlodzimierz, additional, Abdelbaki, Khaled, additional, Belohlavek, Jan, additional, Fehske, Wolfgang, additional, Bott, Michael Carlos, additional, Hoegalmen, Geir, additional, Leiro, Marisa Crespo, additional, Ozcan, Ismail Turkay, additional, Mullens, Wilfried, additional, Kryza, Radim, additional, Al-Ani, Riadh, additional, Loboz-Grudzien, Krystyna, additional, Ermoshkina, Lyudmila, additional, Hojerova, Silvia, additional, Fernandez, Alberto Alfredo, additional, Spinarova, Lenka, additional, Lapp, Harald, additional, Bulut, Efraim, additional, Almeida, Filipa, additional, Vishnevsky, Alexander, additional, Belicova, Margita, additional, Pascual, Domingo, additional, Witte, Klaus, additional, Wong, Kenneth, additional, Droogne, Walter, additional, Delforge, Marc, additional, Peterka, Martin, additional, Olbrich, Hans-Georg, additional, Carugo, Stefano, additional, Nessler, Jadwiga, additional, McGill, Thao Huynh, additional, Huegl, Burkhard, additional, Akin, Ibrahim, additional, Moreira, Ilidio, additional, Baglikov, Andrey, additional, Thambyrajah, Jeetendra, additional, Hayes, Chris, additional, Barrionuevo, Marcelo Raul, additional, Yigit, Zerrin, additional, Kaya, Hakki, additional, Klimsa, Zdenek, additional, Radvan, Martin, additional, Kadel, Christoph, additional, Landmesser, Ulf, additional, Di Tano, Giuseppe, additional, Lisik, Malgorzata Buksinska, additional, Fonseca, Candida, additional, Oliveira, Luis, additional, Marques, Irene, additional, Santos, Luis Miguel, additional, Lenner, Egon, additional, Letavay, Peter, additional, Bueno, Manuel Gomez, additional, Mota, Paula, additional, Wong, Aaron, additional, Bailey, Kristian, additional, Foley, Paul, additional, Hasbani, Eduardo, additional, Virani, Sean, additional, Massih, Tony Abdel, additional, Al-Saif, Shukri, additional, Taborsky, Milos, additional, Kaislerova, Marta, additional, Motovska, Zuzana, additional, Cohen, Aron Ariel, additional, Logeart, Damien, additional, Endemann, Dierk, additional, Ferreira, Daniel, additional, Brito, Dulce, additional, Kycina, Peter, additional, Bollano, Entela, additional, Basilio, Enrique Galve, additional, Rubio, Lorenzo Facila, additional, Aguado, Marcos Garcia, additional, Schiavi, Lilia Beatriz, additional, Zivano, Daniel Francisco, additional, Lonn, Eva, additional, El Sayed, Ali, additional, Pouleur, Anne-Catherine, additional, Heyse, Alex, additional, Schee, Alexandr, additional, Polasek, Rostislav, additional, Houra, Marek, additional, Tribouilloy, Christophe, additional, Seronde, Marie France, additional, Galinier, Michel, additional, Noutsias, Michel, additional, Schwimmbeck, Peter, additional, Voigt, Ingo, additional, Westermann, Dirk, additional, Pulignano, Giovanni, additional, Vegsundvaag, Johnny, additional, Da Silva Antunes, Jose Alexandre, additional, Monteiro, Pedro, additional, Stevlik, Jan, additional, Goncalvesova, Eva, additional, Hulkoova, Beata, additional, Castro Fernandez, Antonio Juan, additional, Davies, Ceri, additional, Squire, Iain, additional, Meyer, Philippe, additional, Sheppard, Richard, additional, Sahin, Tayfun, additional, Sochor, Karel, additional, De Geeter, Guillaume, additional, Schmeisser, Alexander, additional, Weil, Joachim, additional, Soares, Ana Oliveira, additional, Vasilevna, Olga Bulashova, additional, Oshurkov, Andrey, additional, Sunderland, Shahid Junejo, additional, Glover, Jason, additional, Exequiel, Tomas, additional, Decoulx, Eric, additional, Meyer, Sven, additional, Muenzel, Thomas, additional, Frioes, Fernando, additional, Arbolishvili, Georgy, additional, Tokarcikova, Anna, additional, Karlstrom, Patric, additional, Trullas Vila, Joan Carles, additional, Perez, Gonzalo Pena, additional, Sankaranarayanan, Rajiv, additional, Nageh, Thuraia, additional, Alasia, Diego Cristian, additional, Refaat, Marwan, additional, Demirkan, Burcu, additional, Al-Buraiki, Jehad, additional, and Karabsheh, Shadi, additional

Published
2020
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18. Initiation of sacubitril/valsartan in haemodynamically stabilised heart failure patients in hospital or early after discharge: primary results of the randomised TRANSITION study

Author

Wachter, Rolf, Senni, Michele, Belohlavek, Jan, Straburzynska‐Migaj, Ewa, Witte, Klaus K., Kobalava, Zhanna, Fonseca, Candida, Goncalvesova, Eva, Cavusoglu, Yuksel, Fernandez, Alberto, Chaaban, Said, Bøhmer, Ellen, Pouleur, Anne‐Catherine, Mueller, Christian, Tribouilloy, Christophe, Lonn, Eva, A.L. Buraiki, Jehad, Gniot, Jacek, Mozheiko, Maria, Lelonek, Malgorzata, Noè, Adele, Schwende, Heike, Bao, Weibin, Butylin, Dmytro, Pascual‐Figal, Domingo, Dominguez, Antonio Reyes, Horacek, Thomas, del Rio, Enrique Garcia, Mueller, Christian Eugen, Straburzynska-Migaj, Ewa, Slanina, Miroslav, vom Dahl, Juergen, Ryding, Alisdair, Moriarty, Andrew, Robles, Manuel Beltran, Villota, Julio Nunez, Quintana, Antonio Garcia, Nitschke, Thorsten, Manuel Garcia Pinilla, Jose, Bonet, Luis Almenar, Filali zaatari, MD, Samia, Spinar, Jindrich, Musial, Wlodzimierz, Abdelbaki, Khaled, Fehske, Wolfgang, Bott, Michael Carlos, Hoegalmen, Geir, Leiro, Marisa Crespo, Ozcan, Ismail Turkay, Mullens, Wilfried, Kryza, Radim, Al-Ani, Riadh, Loboz-Grudzien, Krystyna, Ermoshkina, Lyudmila, Hojerova, Silvia, Fernandez, Alberto Alfredo, Spinarova, Lenka, Lapp, Harald, Bulut, Efraim, Almeida, Filipa, Vishnevsky, Alexander, Belicova, Margita, Pascual, Domingo, Witte, Klaus, Wong, Kenneth, Droogne, Walter, Delforge, Marc, Peterka, Martin, Olbrich, Hans‐Georg, Carugo, Stefano, Nessler, Jadwiga, McGill, Thao Huynh, Huegl, Burkhard, Akin, Ibrahim, Moreira, Ilidio, Baglikov, Andrey, Thambyrajah, Jeetendra, Hayes, Chris, Barrionuevo, Marcelo Raul, Yigit, Zerrin, Kaya, Hakki, Klimsa, Zdenek, Radvan, Martin, Kadel, Christoph, Landmesser, Ulf, Di Tano, Giuseppe, Lisik, Malgorzata Buksinska, Oliveira, Luis, Marques, Irene, Santos, Luis Miguel, Lenner, Egon, Letavay, Peter, Bueno, Manuel Gomez, Mota, Paula, Wong, Aaron, Bailey, Kristian, Foley, Paul, Hasbani, Eduardo, Virani, Sean, Massih, Tony Abdel, Al‐Saif, Shukri, Taborsky, Milos, Kaislerova, Marta, Motovska, Zuzana, Praha, Cohen, Aron Ariel, Logeart, Damien, Endemann, Dierk, Ferreira, Daniel, Brito, Dulce, Kycina, Peter, Bollano, Entela, Basilio, Enrique Galve, Rubio, Lorenzo Facila, Aguado, Marcos Garcia, Schiavi, Lilia Beatriz, Zivano, Daniel Francisco, Sayed, Ali El, Heyse, Alex, Schee, Alexandr, Polasek, Rostislav, Houra, Marek, Seronde, Marie France, Galinier, Michel, Noutsias, Michel, Schwimmbeck, Peter, Voigt, Ingo, Westermann, Dirk, Pulignano, Giovanni, Vegsundvaag, Johnny, Alexandre Da Silva Antunes, Jose, Monteiro, Pedro, Stevlik, Jan, Hulkoova, Beata, Juan Castro Fernandez, Antonio, Davies, Ceri, Squire, Iain, Meyer, Philippe, Sheppard, Richard, Sahin, Tayfun, Sochor, Karel, De Geeter, Guillaume, Schmeisser, Alexander, Weil, Joachim, Soares, Ana Oliveira, Vasilevna, Olga Bulashova, Oshurkov, Andrey, Sunderland, Shahid Junejo, Glover, Jason, Exequiel, Tomas, Decoulx, Eric, Meyer, Sven, Muenzel, Thomas, Frioes, Fernando, Arbolishvili, Georgy, Tokarcikova, Anna, Karlstrom, Patric, Carles Trullas Vila, Joan, Perez, Gonzalo Pena, Sankaranarayanan, Rajiv, Nageh, Thuraia, Alasia, Diego Cristian, Refaat, Marwan, Demirkan, Burcu, Al-Buraiki, Jehad, Karabsheh, Shadi, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Service de pathologie cardiovasculaire, Wachter, R, Senni, M, Belohlavek, J, Straburzynska-Migaj, E, Witte, K, Kobalava, Z, Fonseca, C, Goncalvesova, E, Cavusoglu, Y, Fernandez, A, Chaaban, S, Bøhmer, E, Pouleur, A, Mueller, C, Tribouilloy, C, Lonn, E, A L Buraiki, J, Gniot, J, Mozheiko, M, Lelonek, M, Noè, A, Schwende, H, Bao, W, Butylin, D, Pascual-Figal, D, and Transition, I

Subjects
Male, medicine.medical_specialty, Acute decompensated heart failure, Tetrazoles, Heart failure, 030204 cardiovascular system & hematology, Sacubitril, 03 medical and health sciences, Angiotensin Receptor Antagonists, 0302 clinical medicine, Internal medicine, medicine, Clinical endpoint, Hospitalisation, Humans, Sacubitril/valsartan, Aged, Angiotensin receptor–neprilysin inhibitor, Heart Failure, Ejection fraction, Dose-Response Relationship, Drug, business.industry, Aminobutyrates, Biphenyl Compounds, Hemodynamics, medicine.disease, Angiotensin receptor-neprilysin inhibitor, Patient Discharge, 3. Good health, Discontinuation, Drug Combinations, Treatment Outcome, Valsartan, Tolerability, Female, Neprilysin, business, Cardiology and Cardiovascular Medicine, Sacubitril, Valsartan, medicine.drug, Follow-Up Studies
Abstract

AIMS: To assess tolerability and optimal time point for initiation of sacubitril/valsartan in patients stabilised after acute heart failure (AHF). METHODS AND RESULTS: TRANSITION was a randomised, multicentre, open-label study comparing two treatment initiation modalities of sacubitril/valsartan. Patients aged ≥ 18 years, hospitalised for AHF were stratified according to pre-admission use of renin-angiotensin-aldosterone system inhibitors and randomised (n = 1002) after stabilisation to initiate sacubitril/valsartan either ≥ 12-h pre-discharge or between Days 1-14 post-discharge. Starting dose (as per label) was 24/26 mg or 49/51 mg bid with up- or down-titration based on tolerability. The primary endpoint was the proportion of patients attaining 97/103 mg bid target dose after 10 weeks. Median time of first dose of sacubitril/valsartan from the day of discharge was Day -1 and Day +1 in the pre-discharge group and the post-discharge group, respectively. Comparable proportions of patients in the pre- and post-discharge initiation groups met the primary endpoint [45.4% vs. 50.7%; risk ratio (RR) 0.90; 95% confidence interval (CI) 0.79-1.02]. The proportion of patients who achieved and maintained for ≥ 2 weeks leading to Week 10, either 49/51 or 97/103 mg bid was 62.1% vs. 68.5% (RR 0.91; 95% CI 0.83-0.99); or any dose was 86.0% vs. 89.6% (RR 0.96; 95% CI 0.92-1.01). Discontinuation due to adverse events occurred in 7.3% vs. 4.9% of patients (RR 1.49; 95% CI 0.90-2.46). CONCLUSIONS: Initiation of sacubitril/valsartan in a wide range of heart failure with reduced ejection fraction patients stabilised after an AHF event, either in hospital or shortly after discharge, is feasible with about half of the patients achieving target dose within 10 weeks. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov ID: NCT02661217. © 2019 The Authors. European Journal of Heart Failure published by John Wiley & Sons peerReviewed

Published
2019

29. Myocardial-Perfusion-SPECT Update S1-Guideline

Author

Lindner, Oliver, Bengel, Frank, Burchert, Wolfgang, Doerr, Rolf, Hacker, Marcus, Schaefer, Wolfgang, Schaefers, Michael A., Schmidt, Matthias, Schwaiger, Markus, vom Dahl, Juergen, Zimmermann, Rainer, Lindner, Oliver, Bengel, Frank, Burchert, Wolfgang, Doerr, Rolf, Hacker, Marcus, Schaefer, Wolfgang, Schaefers, Michael A., Schmidt, Matthias, Schwaiger, Markus, vom Dahl, Juergen, and Zimmermann, Rainer

Abstract

The S1 guideline for myocardial perfusion SPECT has been published by the Association of the Scientific Medical Societies in Germany (AWMF) and is valid until 2/2022. This paper is a short summary with comments on all chapters and subchapters wich were modified and amended.

Published
2017

30. PROGNOSTIC USEFULNESS OF ADREVIEW SCINTIGRAPHY IN IDENTIFYING HEART FAILURE PATIENTS AT LOWER RISK OF DEATH DURING 5-YEAR FOLLOW-UP IN THE ADMIRE-HF STUDY

Author

Senior, Roxy, primary, Friberg, Lars, additional, Travin, Mark, additional, Hudnut, Franc, additional, Chandna, Harish, additional, Agostini, Denis, additional, Ananth, Karthikeyan, additional, Miyamoto, Micahael, additional, Shah, Mahesh, additional, Koren, Michael, additional, vom Dahl, Juergen, additional, and Levy, Wayne, additional

Published
2016
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33. Rotational Atherectomy Does Not Reduce Recurrent In-Stent Restenosis

Author

vom Dahl, Juergen, primary, Dietz, Ulrich, additional, Haager, Philipp K., additional, Silber, Sigmund, additional, Niccoli, Luigi, additional, Buettner, Hans Juergen, additional, Schiele, Francois, additional, Thomas, Martyn, additional, Commeau, Philippe, additional, Ramsdale, David R., additional, Garcia, Eulogio, additional, Hamm, Christian W., additional, Hoffmann, Rainer, additional, Reineke, Thorsten, additional, and Klues, Heinrich G., additional

Published
2002
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42. Myocyte degeneration and cell death in hibernating human myocardium

Author

Schwartz, Ernst R., primary, Schaper, Jutta, additional, vom Dahl, Juergen, additional, Altehoefer, Carsten, additional, Grohmann, Beate, additional, Schoendube, Friedrich, additional, Sheehan, Florence H., additional, Uebis, Rainer, additional, Buell, Udalrich, additional, Messmer, Bruno J., additional, Schaper, Wolfgang, additional, and Hanrath, Peter, additional

Published
1996
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