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Covid-19 triage in the emergency department 2.0: how analytics and AI transform a human-made algorithm for the prediction of clinical pathways

Authors :
Bartenschlager, Christina C.
Grieger, Milena
Erber, Johanna
Neidel, Tobias
Borgmann, Stefan
Vehreschild, Jörg J.
Steinbrecher, Markus
Rieg, Siegbert
Stecher, Melanie
Dhillon, Christine
Ruethrich, Maria M.
Jakob, Carolin E. M.
Hower, Martin
Heller, Axel R.
Vehreschild, Maria
Wyen, Christoph
Messmann, Helmut
Piepel, Christiane
Brunner, Jens O.
Hanses, Frank
Römmele, Christoph
Spinner, Christoph
Ruethrich, Maria Madeleine
Lanznaster, Julia
Wille, Kai
Tometten, Lukas
Dolff, Sebastian
von Bergwelt-Baildon, Michael
Merle, Uta
Rothfuss, Katja
Isberner, Nora
Jung, Norma
Göpel, Siri
vom Dahl, Juergen
Degenhardt, Christian
Strauss, Richard
Gruener, Beate
Eberwein, Lukas
Hellwig, Kerstin
Rauschning, Dominic
Neufang, Mark
Westhoff, Timm
Raichle, Claudia
Akova, Murat
Jensen, Bjoern-Erik
Schubert, Joerg
Grunwald, Stephan
Friedrichs, Anette
Trauth, Janina
de With, Katja
Guggemos, Wolfgang
Kielstein, Jan
Heigener, David
Markart, Philipp
Bals, Robert
Stieglitz, Sven
Voigt, Ingo
Taubel, Jorg
Milovanovic, Milena
Publication Year :
2023

Abstract

The Covid-19 pandemic has pushed many hospitals to their capacity limits. Therefore, a triage of patients has been discussed controversially primarily through an ethical perspective. The term triage contains many aspects such as urgency of treatment, severity of the disease and pre-existing conditions, access to critical care, or the classification of patients regarding subsequent clinical pathways starting from the emergency department. The determination of the pathways is important not only for patient care, but also for capacity planning in hospitals. We examine the performance of a human-made triage algorithm for clinical pathways which is considered a guideline for emergency departments in Germany based on a large multicenter dataset with over 4,000 European Covid-19 patients from the LEOSS registry. We find an accuracy of 28 percent and approximately 15 percent sensitivity for the ward class. The results serve as a benchmark for our extensions including an additional category of palliative care as a new label, analytics, AI, XAI, and interactive techniques. We find significant potential of analytics and AI in Covid-19 triage regarding accuracy, sensitivity, and other performance metrics whilst our interactive human-AI algorithm shows superior performance with approximately 73 percent accuracy and up to 76 percent sensitivity. The results are independent of the data preparation process regarding the imputation of missing values or grouping of comorbidities. In addition, we find that the consideration of an additional label palliative care does not improve the results.

Subjects

Subjects :
ddc:610

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.od......3341..d27f122451f43367f34bc9e655d01e3b