1. Spectral Aggregate of the High-Passed Fundamental Frequency and Its Relationship to the Primary Acoustic Features of Adductor Laryngeal Dystonia
- Author
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Marks, Katherine L., Feaster, Taylor F., Baker, Sarah, Diaz-Cadiz, Manuel E., Doyle, Philip C., and Stepp, Cara E.
- Subjects
Voice -- Analysis ,Botulinum toxin -- Dosage and administration ,Dystonia -- Diagnosis -- Care and treatment ,Health - Abstract
Objective: Currently, no clinically feasible objective measures exist that are specific to the signs of adductor laryngeal dystonia (LD), deterring effective diagnosis and treatment. This project sought to establish concurrent validity of a new automated acoustic outcome measure, designed to be specific to adductor laryngeal dystonia (AdLD): the spectral aggregate of the high-passed fundamental frequency contour (SAH[f.sub.o]). Method: Twenty speakers with AdLD read voiced phoneme-loaded (more symptomatic) and voiceless phoneme-loaded (less symptomatic) sentences. LD discontinuities (defined as phonatory breaks, frequency shifts, and creak), the acoustic ramifications of laryngeal spasms, were manually identified. The frequency content of the [f.sub.o] contour was examined as a function of time, and content above 1000 Hz was summed to automatically calculate SAH[f.sub.o]. Multiple linear regression analysis was applied to SAH[f.sub.o] based on LD discontinuities and sentence type (voiced or voiceless phoneme-loaded). Results: The regression model accounted for 41.1% of the variance in SAH[f.sub.o]. Both the LD discontinuities and sentence type were statistically related to SAH[f.sub.o]. Conclusion: Results of this study provide evidence of concurrent validity. SAH[f.sub.o] is an automatic outcome measure specific to acoustic signs of AdLD that may be useful to track treatment progress., Laryngeal dystonia (LD), also known as spasmodic dysphonia, is a neurological focal dystonia of the laryngeal musculature (Blitzer et al., 2018). There are two main types of LD, differentiated by [...]
- Published
- 2022
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