248 results on '"Veldhuizen, Maria"'
Search Results
2. Distraction suppresses high-fat flavor perception
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Razzaghi-Asl, Sara, Doğan, Sümeyra Nur, Tekatlı, Muhammet Tahir, and Veldhuizen, Maria Geraldine
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- 2024
- Full Text
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3. Diverse minds in early medieval England
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Veldhuizen, Maria Elisabeth, O'Doherty, Marianne, Richardson, Anthony J., and May, William
- Abstract
In this thesis, descriptions of minds in primary sources are explored in order to come to a better understanding of the range of concepts of minds and their functioning existed in the early medieval period (600-1100) in England. This research project responds critically to scholarship on early medieval minds that centralises a standard or ideal model of the mind, influenced by modern medical concepts and philosophical traditions, but that tends to exclude descriptions of minds in the primary sources that conflict with this idea of the mind. The diversity of concepts in texts from early medieval England suggests that conventional models of the early medieval mind should be re-examined, nuanced and enlarged. The primary literature encompasses a wide range of descriptions of minds that are not easily categorised in terms of health or normality, but which instead depict minds as diverse, changing and contingent on physical and emotional state, stage in life, and so on. Furthermore, early medieval concepts of mind appear to include minds and cognitive processes that extend or travel outside the human body, that are non-human in origin, and that continue to exist after death. Recognising such descriptions as part of early medieval ideas about minds transforms our comprehension of historical perspectives on minds and mental activity, with further implications for a wide range of fields of study, such as research into relics or objects. By engaging both with modern models and paradigms, as well as bringing together a wide range of primary material, this thesis opens a discussion about early medieval minds that goes beyond normality and dysfunction to acknowledge variety, diversity and difference.
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- 2021
4. Recent Smell Loss Is the Best Predictor of COVID-19 Among Individuals With Recent Respiratory Symptoms.
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Gerkin, Richard, Ohla, Kathrin, Veldhuizen, Maria, Joseph, Paule, Kelly, Christine, Bakke, Alyssa, Steele, Kimberley, Farruggia, Michael, Pellegrino, Robert, Pepino, Marta, Bouysset, Cédric, Soler, Graciela, Pereda-Loth, Veronica, Dibattista, Michele, Cooper, Keiland, Croijmans, Ilja, Di Pizio, Antonella, Ozdener, Mehmet, Fjaeldstad, Alexander, Lin, Cailu, Sandell, Mari, Singh, Preet, Brindha, V, Olsson, Shannon, Saraiva, Luis, Ahuja, Gaurav, Alwashahi, Mohammed, Bhutani, Surabhi, DErrico, Anna, Fornazieri, Marco, Golebiowski, Jérôme, Dar Hwang, Liang, Öztürk, Lina, Roura, Eugeni, Spinelli, Sara, Whitcroft, Katherine, Faraji, Farhoud, Fischmeister, Florian, Heinbockel, Thomas, Hsieh, Julien, Huart, Caroline, Konstantinidis, Iordanis, Menini, Anna, Morini, Gabriella, Olofsson, Jonas, Philpott, Carl, Pierron, Denis, Shields, Vonnie, Voznessenskaya, Vera, Albayay, Javier, Altundag, Aytug, Bensafi, Moustafa, Bock, María, Calcinoni, Orietta, Fredborg, William, Laudamiel, Christophe, Lim, Juyun, Lundström, Johan, Macchi, Alberto, Meyer, Pablo, Moein, Shima, Santamaría, Enrique, Sengupta, Debarka, Rohlfs Dominguez, Paloma, Yanik, Hüseyin, Hummel, Thomas, Hayes, John, Reed, Danielle, Niv, Masha, Munger, Steven, and Parma, Valentina
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anosmia ,chemosensory ,coronavirus ,hyposmia ,olfactory ,prediction ,Adult ,Anosmia ,COVID-19 ,Cross-Sectional Studies ,Female ,Humans ,Male ,Middle Aged ,Prognosis ,SARS-CoV-2 ,Self Report ,Smell - Abstract
In a preregistered, cross-sectional study, we investigated whether olfactory loss is a reliable predictor of COVID-19 using a crowdsourced questionnaire in 23 languages to assess symptoms in individuals self-reporting recent respiratory illness. We quantified changes in chemosensory abilities during the course of the respiratory illness using 0-100 visual analog scales (VAS) for participants reporting a positive (C19+; n = 4148) or negative (C19-; n = 546) COVID-19 laboratory test outcome. Logistic regression models identified univariate and multivariate predictors of COVID-19 status and post-COVID-19 olfactory recovery. Both C19+ and C19- groups exhibited smell loss, but it was significantly larger in C19+ participants (mean ± SD, C19+: -82.5 ± 27.2 points; C19-: -59.8 ± 37.7). Smell loss during illness was the best predictor of COVID-19 in both univariate and multivariate models (ROC AUC = 0.72). Additional variables provide negligible model improvement. VAS ratings of smell loss were more predictive than binary chemosensory yes/no-questions or other cardinal symptoms (e.g., fever). Olfactory recovery within 40 days of respiratory symptom onset was reported for ~50% of participants and was best predicted by time since respiratory symptom onset. We find that quantified smell loss is the best predictor of COVID-19 amongst those with symptoms of respiratory illness. To aid clinicians and contact tracers in identifying individuals with a high likelihood of having COVID-19, we propose a novel 0-10 scale to screen for recent olfactory loss, the ODoR-19. We find that numeric ratings ≤2 indicate high odds of symptomatic COVID-19 (4 < OR < 10). Once independently validated, this tool could be deployed when viral lab tests are impractical or unavailable.
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- 2021
5. More than smell – COVID-19 is associated with severe impairment of smell, taste, and chemesthesis
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Parma, Valentina, Ohla, Kathrin, Veldhuizen, Maria G, Niv, Masha Y, Kelly, Christine E, Bakke, Alyssa J, Cooper, Keiland W, Bouysset, Cédric, Pirastu, Nicola, Dibattista, Michele, Kaur, Rishemjit, Liuzza, Marco Tullio, Pepino, Marta Y, Schöpf, Veronika, Pereda-Loth, Veronica, Olsson, Shannon B, Gerkin, Richard C, Domínguez, Paloma Rohlfs, Albayay, Javier, Farruggia, Michael C, Bhutani, Surabhi, Fjaeldstad, Alexander W, Kumar, Ritesh, Menini, Anna, Bensafi, Moustafa, Sandell, Mari, Konstantinidis, Iordanis, Di Pizio, Antonella, Genovese, Federica, Öztürk, Lina, Thomas-Danguin, Thierry, Frasnelli, Johannes, Boesveldt, Sanne, Saatci, Özlem, Saraiva, Luis R, Lin, Cailu, Golebiowski, Jérôme, Hwang, Liang-Dar, Ozdener, Mehmet Hakan, Guàrdia, Maria Dolors, Laudamiel, Christophe, Ritchie, Marina, Havlícek, Jan, Pierron, Denis, Roura, Eugeni, Navarro, Marta, Nolden, Alissa A, Lim, Juyun, Whitcroft, KL, Colquitt, Lauren R, Ferdenzi, Camille, Brindha, Evelyn V, Altundag, Aytug, Macchi, Alberto, Nunez-Parra, Alexia, Patel, Zara M, Fiorucci, Sébastien, Philpott, Carl M, Smith, Barry C, Lundström, Johan N, Mucignat, Carla, Parker, Jane K, van den Brink, Mirjam, Schmuker, Michael, Fischmeister, Florian Ph S, Heinbockel, Thomas, Shields, Vonnie DC, Faraji, Farhoud, Santamaría, Enrique, Fredborg, William EA, Morini, Gabriella, Olofsson, Jonas K, Jalessi, Maryam, Karni, Noam, D’Errico, Anna, Alizadeh, Rafieh, Pellegrino, Robert, Meyer, Pablo, Huart, Caroline, Chen, Ben, Soler, Graciela M, Alwashahi, Mohammed K, Welge-Lüssen, Antje, Freiherr, Jessica, de Groot, Jasper HB, Klein, Hadar, Okamoto, Masako, Singh, Preet Bano, Hsieh, Julien W, Reed, Danielle R, Hummel, Thomas, Munger, Steven D, Hayes, John E, Abdulrahman, Olagunju, Dalton, Pamela, Yan, Carol H, Voznessenskaya, Vera V, Chen, Jingguo, Sell, Elizabeth A, and Walsh-Messinger, Julie
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Neurosciences ,Dental/Oral and Craniofacial Disease ,Clinical Research ,Adult ,Aged ,Betacoronavirus ,COVID-19 ,Coronavirus Infections ,Female ,Humans ,Male ,Middle Aged ,Olfaction Disorders ,Pandemics ,Pneumonia ,Viral ,SARS-CoV-2 ,Self Report ,Smell ,Somatosensory Disorders ,Surveys and Questionnaires ,Taste ,Taste Disorders ,Young Adult ,head and neck surgery ,olfaction ,somatosensation ,GCCR Group Author ,Biological Sciences ,Neurology & Neurosurgery - Abstract
Recent anecdotal and scientific reports have provided evidence of a link between COVID-19 and chemosensory impairments, such as anosmia. However, these reports have downplayed or failed to distinguish potential effects on taste, ignored chemesthesis, and generally lacked quantitative measurements. Here, we report the development, implementation, and initial results of a multilingual, international questionnaire to assess self-reported quantity and quality of perception in 3 distinct chemosensory modalities (smell, taste, and chemesthesis) before and during COVID-19. In the first 11 days after questionnaire launch, 4039 participants (2913 women, 1118 men, and 8 others, aged 19-79) reported a COVID-19 diagnosis either via laboratory tests or clinical assessment. Importantly, smell, taste, and chemesthetic function were each significantly reduced compared to their status before the disease. Difference scores (maximum possible change ±100) revealed a mean reduction of smell (-79.7 ± 28.7, mean ± standard deviation), taste (-69.0 ± 32.6), and chemesthetic (-37.3 ± 36.2) function during COVID-19. Qualitative changes in olfactory ability (parosmia and phantosmia) were relatively rare and correlated with smell loss. Importantly, perceived nasal obstruction did not account for smell loss. Furthermore, chemosensory impairments were similar between participants in the laboratory test and clinical assessment groups. These results show that COVID-19-associated chemosensory impairment is not limited to smell but also affects taste and chemesthesis. The multimodal impact of COVID-19 and the lack of perceived nasal obstruction suggest that severe acute respiratory syndrome coronavirus strain 2 (SARS-CoV-2) infection may disrupt sensory-neural mechanisms.
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- 2020
6. International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020).
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Farmer, Adam, Strzelczyk, Adam, Finisguerra, Alessandra, Gourine, Alexander, Gharabaghi, Alireza, Hasan, Alkomiet, Burger, Andreas, Jaramillo, Andrés, Mertens, Ann, Majid, Arshad, Verkuil, Bart, Badran, Bashar, Ventura-Bort, Carlos, Gaul, Charly, Beste, Christian, Warren, Christopher, Quintana, Daniel, Hämmerer, Dorothea, Freri, Elena, Frangos, Eleni, Tobaldini, Eleonora, Kaniusas, Eugenijus, Rosenow, Felix, Capone, Fioravante, Panetsos, Fivos, Ackland, Gareth, Kaithwas, Gaurav, OLeary, Georgia, Genheimer, Hannah, Jacobs, Heidi, Van Diest, Ilse, Schoenen, Jean, Redgrave, Jessica, Fang, Jiliang, Deuchars, Jim, Széles, Jozsef, More, Kaushik, Vonck, Kristl, Steenbergen, Laura, Vianna, Lauro, McTeague, Lisa, Ludwig, Mareike, Veldhuizen, Maria, De Couck, Marijke, Casazza, Marina, Keute, Marius, Bikson, Marom, Andreatta, Marta, DAgostini, Martina, Weymar, Mathias, Betts, Matthew, Prigge, Matthias, Kaess, Michael, Roden, Michael, Thai, Michelle, Schuster, Nathaniel, Montano, Nicola, Hansen, Niels, Kroemer, Nils, Rong, Peijing, Fischer, Rico, Howland, Robert, Sclocco, Roberta, Sellaro, Roberta, Garcia, Ronald, Bauer, Sebastian, Gancheva, Sofiya, Stavrakis, Stavros, Kampusch, Stefan, Deuchars, Susan, Wehner, Sven, Laborde, Sylvain, Usichenko, Taras, Polak, Thomas, Zaehle, Tino, Borges, Uirassu, Teckentrup, Vanessa, Jandackova, Vera, Napadow, Vitaly, Koenig, Julian, and Thayer, Julian
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guidelines & recommendations ,minimum reporting standards ,transcutaneous auricular vagus nerve stimulation ,transcutaneous cervical vagus nerve stimulation ,transcutaneous vagus nerve stimulation - Abstract
Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation (tVNS) across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation(VNS) and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice.
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- 2020
7. Non-invasive vagus nerve stimulation in a hungry state decreases heart rate variability
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Altınkaya, Zeynep, Öztürk, Lina, Büyükgüdük, İlkim, Yanık, Hüseyin, Yılmaz, Dilan Deniz, Yar, Berçem, Değirmenci, Evren, Dal, Uğur, and Veldhuizen, Maria Geraldine
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- 2023
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8. Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits
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May-Wilson, Sebastian, Matoba, Nana, Wade, Kaitlin H., Hottenga, Jouke-Jan, Concas, Maria Pina, Mangino, Massimo, Grzeszkowiak, Eryk J., Menni, Cristina, Gasparini, Paolo, Timpson, Nicholas J., Veldhuizen, Maria G., de Geus, Eco, Wilson, James F., and Pirastu, Nicola
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- 2022
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9. Short-Term Consumption of Sucralose with, but Not without, Carbohydrate Impairs Neural and Metabolic Sensitivity to Sugar in Humans
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Dalenberg, Jelle R., Patel, Barkha P., Denis, Raphael, Veldhuizen, Maria G., Nakamura, Yuko, Vinke, Petra C., Luquet, Serge, and Small, Dana M.
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- 2020
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10. Post-traumatic olfactory loss and brain response beyond olfactory cortex
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Pellegrino, Robert, Farruggia, Michael C., Small, Dana M., and Veldhuizen, Maria G.
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- 2021
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11. Taste-related reward is associated with weight loss following bariatric surgery
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Smith, Kimberly R., Papantoni, Afroditi, Veldhuizen, Maria G., Kamath, Vidyulata, Harris, Civonnia, Moran, Timothy H., Carnell, Susan, and Steele, Kimberley E.
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Surgery -- Health aspects ,Obesity -- Care and treatment ,Bariatric surgery -- Health aspects ,Body mass index -- Health aspects ,Weight loss maintenance -- Health aspects ,Health care industry ,Johns Hopkins University. School of Medicine - Abstract
BACKGROUND. Bariatric surgeries are the most effective treatments for successful and sustained weight loss, but individuals vary in treatment response. Understanding the neurobiological and behavioral mechanisms accounting for this variation could lead to the development of personalized therapeutic approaches and improve treatment outcomes. The primary objectives of this study were to investigate changes in taste preferences and taste-induced brain responses after Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG) and to identify potential taste-related predictors of weight loss. METHODS. Females, ages 18 to 55, with a body mass index greater than or equal to 35 kg/[m.sup.2], and approved for bariatric surgery at the Johns Hopkins Center for Bariatric Surgery were recruited for participation. Demographics, anthropometrics, liking ratings, and neural responses to varying concentrations of sucrose plus fat mixtures were assessed before and after surgery via visual analog scales and functional MRI. RESULTS. Bariatric surgery produced decreases in liking for sucrose-sweetened mixtures. Greater preference for sucrose-sweetened mixtures before surgery was associated with greater weight loss in RYGB, but not VSG. In the RYGB group only, individuals who showed lower taste-induced activation in the ventral tegmental area (VTA) before surgery and greater changes in taste-induced VTA activation 2 weeks following surgery experienced increased weight loss. CONCLUSION. The anatomical and/or metabolic changes associated with RYGB may more effectively 'reset' the neural processing of reward stimuli, thereby rescuing the blunted activation in the mesolimbic pathway found in patients with obesity. Further, these findings suggest that RYGB may be particularly effective in patients with a preference for sweet foods. FUNDING. NIH K23DK100559 and Dalio Philanthropies., Introduction Bariatric surgery results in substantial and sustained weight loss, making it the most successful treatment to date for obesity (1-3). The 2 most common bariatric interventions are the Roux-en-Y [...]
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- 2020
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12. Sweet taste potentiates the reinforcing effects of e-cigarettes
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Kroemer, Nils B., Veldhuizen, Maria G., Delvy, Roberta, Patel, Barkha P., O'Malley, Stephanie S., and Small, Dana M.
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- 2018
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13. Odor imagery but not perception drives risk for food cue reactivity and increased adiposity
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Perszyk, Emily E., primary, Davis, Xue S., additional, Djordjevic, Jelena, additional, Jones-Gotman, Marilyn, additional, Trinh, Jessica, additional, Hutelin, Zach, additional, Veldhuizen, Maria G., additional, Koban, Leonie, additional, Wager, Tor D., additional, Kober, Hedy, additional, and Small, Dana M., additional
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- 2023
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14. Covid-19 affects taste independently of smell: results from a combined chemosensory home test and online survey from a global cohort (N=10,953)
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Nguyen, Ha, primary, Albayay, Javier, additional, Höchenberger, Richard, additional, Bhutani, Surabhi, additional, Boesveldt, Sanne, additional, Busch, Niko A., additional, Croijmans, Ilja, additional, Cooper, Keiland W., additional, de Groot, Jasper H. B., additional, Farruggia, Michael C., additional, Fjaeldstad, Alexander W., additional, Hayes, John E., additional, Hummel, Thomas, additional, Joseph, Paule V., additional, Laktionova, Tatiana K., additional, Thomas-Danguin, Thierry, additional, Veldhuizen, Maria G., additional, Voznessenskaya, Vera V., additional, Parma, Valentina, additional, Pepino, M. Yanina, additional, and Ohla, Kathrin, additional
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- 2023
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15. Mouthwateringly Good: Swallowing Frequency As A Proxy For Food Advertisement Efficacy
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Öztürk, Lina, primary, Yanık, Hüseyin, additional, and Veldhuizen, Maria, additional
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- 2023
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16. Covid-19 affects taste independent of taste–smell confusions: results from a combined chemosensory home test and online survey from a large global cohort
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Nguyen, Ha, primary, Albayay, Javier, additional, Höchenberger, Richard, additional, Bhutani, Surabhi, additional, Boesveldt, Sanne, additional, Busch, Niko A, additional, Croijmans, Ilja, additional, Cooper, Keiland W, additional, de Groot, Jasper H B, additional, Farruggia, Michael C, additional, Fjaeldstad, Alexander W, additional, Hayes, John E, additional, Hummel, Thomas, additional, Joseph, Paule V, additional, Laktionova, Tatiana K, additional, Thomas-Danguin, Thierry, additional, Veldhuizen, Maria G, additional, Voznessenskaya, Vera V, additional, Parma, Valentina, additional, Pepino, M Yanina, additional, and Ohla, Kathrin, additional
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- 2023
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17. Editorial: The functional connectome of chemosensory perception
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Fischmeister, Florian Ph.S, primary, Veldhuizen, Maria G., additional, and Cecchetto, Cinzia, additional
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- 2022
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18. Micturition Drive is Associated with Decreased Brain Response to Palatable Milkshake in the Human Anterior Insular Cortex
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Gao, Xiao, Sun, Xue, Veldhuizen, Maria G., Nakamura, Yuko, Kroemer, Nils B., and Small, Dana
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- 2016
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19. GCCR003: Follow-up study on the relation between COVID-19 and long-term chemosensory loss
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Reed, Danielle, Parma, Valentina, Veldhuizen, Maria, Ohla, Kathrin, Bakke, Allysa, Exten, Cara, Hayes, John, Ozdener, Mehmet, Koyama, Sachiko, Fjaeldstad, Alexander, Chen, Jing-guo, de Groot, Jasper, cantone, elena, Farruggia, Michael, Philpott, Carl, Soler, Graciela, Calcinoni, Orietta, Konstantinidis, Iordanis, Boesveldt, Sanne, Alwashahi, Mohammed, Overdevest, Jonathan, Zobairy, Hosna, Pierron, Denis, Olofsson, Jonas, and Alizadeh, Rafieh
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Smell ,Recovery ,Taste ,Medicine and Health Sciences ,COVID-19 ,Olfaction - Abstract
Preparing for the pre-registration and ensuing analysis
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- 2022
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20. Is olfactory loss a sensitive symptomatic predictor of COVID-19? A preregistered, crowdsourced study
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Parma, Valentina, Veldhuizen, Maria, Ohla, Kathrin, Gerkin, Richard, Reed, Danielle, and Hayes, John
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FOS: Psychology ,Respiratory tract diseases ,Medicine and Health Sciences ,Psychology ,Diseases ,Social and Behavioral Sciences - Abstract
Chemosensory loss has taken on a new meaning for people worldwide as loss of smell (and taste, as well as chemesthesis) has become a prominent symptom of COVID-19, now recognized by health authorities including the CDC. As part of an international effort to better understand this chemosensory connection to COVID-19, the GCCR questionnaire is currently implemented in 32 languages and targets people who have or recently have had an upper respiratory infection (e.g., common cold, influenza, suspected or confirmed COVID-19). The initial analyses of a subset of these data (up to April 18th) confirm substantial loss of smell, taste and moderate chemesthesis loss (e.g., the burn of chili peppers, the cooling of menthol, tingle of carbonation) in individuals with COVID-19; notably, this loss was independent of nasal obstruction. The results (Parma et al., 2020) showed largely overlapping patterns of chemosensory impairment in people with COVID-19 confirmed by laboratory tests versus those diagnosed by symptoms alone (e.g., a clinical assessment by a medical professional). After exploration of the second data tranche of the GCCR dataset up to May 14th (henceforth, May dataset), as detailed in our previous preregistration (https://osf.io/ek8jq/), we discovered that after standard cleaning procedures, we had failed to reach the minimal number of participants (N =480) per group that we had declared previously. We therefore waited additional time to reach and surpass the N = 480 threshold, while we explored the available database. With this new pre-registration, we are reporting our planned analyses of the dataset that will be downloaded on July 3rd (henceforth, July dataset) and that is hence not yet available. This new preregistration aligns with our previous one (https://osf.io/ek8jq/), therefore preserving the main goals of the study. Here, we also refine our hypotheses based on the knowledge gained during initial exploration of the May 14th dataset. Below are the major edits that we have introduced and that we intend to apply to the July dataset: Criteria to determine the C19+ and C19- groups (section 17): based on current analyses, we replicate the previously published drop in smell and taste ratings during vs. before the illness in COVID-19 (Parma et al., 2020). However, we observed small but significant differences in chemosensory ratings between the clinically assessed and the lab tested COVID-19 group. In this new preregistration, we therefore follow a more conservative approach and propose to limit analysis to the comparison of participants who reported to have received a lab test for the C19+ vs. C19- analysis. Characterization of multiple diagnostic groups based on smell ratings, as smell change is the assumed most predictive symptom differentiating COVID-19 from other respiratory illnesses: COVID-19 clinical assessment, COVID-19 positive (C19+) lab tested, COVID-19 negative (C19-) lab tested, Unknown (not diagnosed/tested, yet with symptoms). Inclusion of a new goal: exploration and prediction of post C19+ smell loss recovery. In summary, these are goals being pre-registered for investigation in the July dataset . We will determine if we can replicate the previously published results on smell, taste, chemesthesis and nasal obstruction change during COVID-19 versus before COVID-19 (Parma et al., 2020) in participants reporting clinically assessed and lab tested COVID-19 based on data collected since the first data snapshot GCCR001 collected in April 2020. We will compare chemosensory and nasal obstruction changes of the C19+ with participants reporting to have received a negative COVID-19 lab test (C19-). We will determine if a pattern of chemosensory changes, other symptoms, and/or demographics can be identified that discriminate C19+ vs. C19- We will determine if a pattern of chemosensory changes, other symptoms, and/or demographics can be identified that discriminate those with C19+ who recover from smell loss vs. those who do not within the timeframe of the survey completion.
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- 2022
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21. Chemosensory dysfunction as a reliable marker for COVID-19 in adults with self-reported obesity
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Bhutani, Surabhi, Parma, Valentina, Joseph, Paule, Coppin, Geraldine, and Veldhuizen, Maria
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Health Psychology ,Chemesthesis ,Respiratory Tract Diseases ,Life Sciences ,COVID-19 ,Diseases ,Social and Behavioral Sciences ,FOS: Psychology ,Smell ,Taste ,Medicine and Health Sciences ,Psychology ,Obesity ,Gustation - Abstract
Individuals with underlying chronic health conditions are reported to be at increased risk for COVID-19 infection1. Obesity, in particular, is recognized as a major contributor to the severity of COVID-19 illness, especially in young adults with BMI >30 kg/m22. Despite the severity, COVID-19 symptoms have not been systematically assessed in this population group. Here we propose to systematically describe and compare the symptoms in COVID-19 in adults who self-report to be obese or non-obese. While the mechanisms linking excess body weight with COVID-19 are unclear, it is suggested that a pro-inflammatory status in obese adults may impair the adaptive immune response to influenza virus3. Another unique characteristic of COVID-19 is the loss of smell and/or taste4, now a diagnostic criterion for the illness. Interestingly, impaired smell/taste functions are commonly reported in obese adults without COVID-19, and they are attributed to their chronic inflammatory state5,6. Nonetheless, the reliability of using these chemosensory measures as a diagnostic criterion for COVID-19 illness in the obese population is unknown. This information is clinically significant as it may evaluate whether using smell screening tests is an effective diagnostic tool for obese adults. In this exploratory analysis, we will answer the following questions: Is there a difference in chemosensory perception and related symptomatology in adults with self-reported obesity vs no-obesity during the COVID-19 illness? Is the pre-COVID-19 chemosensory perception significantly different from the post-COVID-19 chemosensory perception in adults with self-reported obesity vs no-obesity? Is the post-COVID-19 chemosensory recovery different in adults with self-reported obesity vs no-obesity? Can the difference in smell ratings pre- vs post-COVID diagnosis predict COVID-19 diagnosis in adults with self-reported obesity vs no-obesity?
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- 2022
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22. GCCR004: The relationship of self-reported chemosensory abilities and experienced chemosensory intensities in the GCCR Taste & Smell Check
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Ohla, Kathrin, Pepino, M., Parma, Valentina, Busch, Niko, Höchenberger, Richard, Reed, Danielle, Veldhuizen, Maria, Farruggia, Michael, de Groot, Jasper, Fjaeldstad, Alexander, Philpott, Carl, Joseph, Paule, and Voznessenskaya, Vera
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Medicine and Health Sciences ,Social and Behavioral Sciences - Abstract
This is the preregistration for an observational online study: the GCCR Smell-&-Taste-Check. It combines 1) an online survey with questions about demographics, health (e.g., medical history, COVID-19 status, COVID-19 symptoms), quantitative self-reported remembered ability to smell, taste, and experience oral irritation (like the burning from chili peppers) as well as the ability to breathe through the nose with 2) a practical part where participants rate the smell and taste intensity of four suggested household items/foods (e.g., the smell of shampoo or the sweetness of sugar). Participants are given visual analogue scales with anchors at both ends that produce quantitative evaluations of self-reported sensory abilities (part 1) and experienced intensity (part 2), respectively. The study was designed to provide a means to test (if used once) or monitor (if used more than once) chemosensory abilities. Here, we propose a first analysis with the aim to assess the relationship between the self-reported chemosensory abilities and the experienced chemosensory intensities.
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- 2022
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23. lab demonstration preregistration
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Razzaghi, Sara and Veldhuizen, Maria
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FOS: Psychology ,ComputerApplications_GENERAL ,Psychology ,Social and Behavioral Sciences ,GeneralLiterature_MISCELLANEOUS - Abstract
just a demo, nothing real
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- 2022
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24. GCCR001 - Quantifying smell, taste and chemesthesis changes in COVID19: a multi-national study
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Veldhuizen, Maria, Parma, Valentina, and Reed, Danielle
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Medicine and Health Sciences ,Social and Behavioral Sciences - Abstract
Anecdotal reports, several archived preprints and a few very recent peer-reviewed studies suggest that alterations in chemosensory function are common in people with COVID-19. However, the type (smell, taste, chemesthesis), severity, and quality of these alterations remains unclear. Particularly, taste and chemesthesis (i.e., chemical activation of the trigeminal, glossopharyngeal, and vagus nerves) have not yet been in the focus of investigations. Furthermore, most prior reports have been limited to single countries. To answer the following research questions we have globally deployed an online questionnaire in over a dozen languages. In this initial report, we will compare respondents from two diagnostic groups, (a) those who report that their COVID-19 diagnosis was confirmed via objective tests (henceforth “lab tested”) compared with (b) respondents who report that their COVID-19 diagnosis was obtained via clinical observation by a medical professional (henceforth, “clinical exam”). We will answer the following questions: Does the self-reported change in smell, taste or chemesthesis function (during vs. before COVID-19 disease) differ between the two diagnostic groups? Is the self-reported change in smell function associated with changes in nasal patency, and does this differ in the two diagnostic groups?
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- 2022
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25. Demo lab preregistration
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Veldhuizen, Maria
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Social and Behavioral Sciences - Abstract
just an example
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- 2022
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26. GCCR0005 - Recovery of smell after COVID-19 or other respiratory illness
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Reed, Danielle, Parma, Valentina, Hayes, John, Weir, Elisabeth, Veldhuizen, Maria, Ohla, Kathrin, Joseph, Paule, Pepino, M., Farruggia, Michael, Heinbockel, Thomas, Bhutani, Surabhi, Cooper, Keiland, Voznessenskaya, Vera, Shields, Vonnie, Boesveldt, Sanne, Koyama, Sachiko, Croijmans, Ilja, Mucignat, Carla, Postma, Elbrich, Kopishinskaia, Svetlana, Chung, Seo-Jin, Laktionova, Tatiana, and de Groot, Jasper
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Post-acute sequelae of COVID-19 ,parosmia ,long-haulers ,GCCR ,Life Sciences ,COVID-19 ,Social and Behavioral Sciences ,taste ,chemosensory ,recovery ,Global Consortium for Chemosensory Research ,Medicine and Health Sciences ,smell ,chemesthesis ,sense organs ,anosmia ,olfaction - Abstract
Adult participants rate their sense of taste and smell at home using common items each week to track changes especially after recovery from COVID-19 or other insults, e.g., or other viral infections.
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- 2022
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27. GCCR001 - More than smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis
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Parma, Valentina, Ohla, Kathrin, Veldhuizen, Maria, Reed, Danielle, Liuzza, Marco Tullio, and Houser, Daniel
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Coronavirus ,taste ,chemosensory ,parosmia ,hyposmia ,phantosmia ,smell ,chemesthesis ,gustatory ,Covid-19 ,olfactory ,anosmia - Abstract
Multi-lingual, international questionnaire to assess self-reported quantity and quality of perception in three distinct chemosensory modalities (smell, taste, and chemesthesis) before and during COVID-19
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- 2022
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28. GCCR002: Value of quantifying smell, taste, and chemesthesis changes in the differential diagnosis of COVID19 vs other respiratory illnesses: a multi-national study
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Parma, Valentina, Veldhuizen, Maria, Ohla, Kathrin, Gerkin, Richard, Reed, Danielle, and Hayes, John
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FOS: Psychology ,taste ,Respiratory Tract Diseases ,Medicine and Health Sciences ,smell ,Psychology ,COVID-19 ,Diseases ,chemesthesis ,Social and Behavioral Sciences ,gustation ,olfaction - Abstract
Chemosensory loss has taken on a new meaning for people worldwide as loss of smell (and taste, as well as chemesthesis) has become a prominent symptom of COVID-19, now recognized by health authorities including the CDC. As part of an international effort to better understand this chemosensory connection to COVID-19, a questionnaire was implemented in 29 languages for people who have had an upper respiratory infection (e.g., common cold, influenza, suspected or confirmed COVID-19). The initial analyses of a subset of these data confirm substantial loss of smell, taste and chemesthesis (e.g., the burn of chili peppers, the cooling of menthol, tingle of carbonation) in individuals with COVID-19; notably, this loss was independent of nasal obstruction. The results had minimal differences between people with COVID-19 confirmed by laboratory tests versus those diagnosed by symptoms alone (e.g., a clinical assessment by a medical professional). In the current study, which builds on these initial findings, our aims are three-fold. We will determine if we can replicate the previous results on smell, taste, chemesthesis and nasal obstruction change during COVID-19 versus before COVID-19 (Parma et al., under review) in participants reporting COVID-19 based on data collected since the initial data snapshot. We will compare chemosensory and nasal obstruction changes of the COVID-19 group with participants reporting other respiratory illnesses (non-COVID respiratory illness or nCRI group) using the data of the supersample (all data since study initiation). We will determine if a pattern of chemosensory changes, other symptoms, and/or demographics can be identified that discriminate COVID-19 from nCRI. Authors of this project: Global Consortium for Chemosensory Research (GCCR) following the GCCR002 collaboration agreement.
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- 2022
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29. Distracted Sniffing of Food Odors Leads to Diminished Behavioral and Neural Responses
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Veldhuizen, Maria Geraldine
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- 2017
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30. Future Directions for Chemosensory Connectomes: Best Practices and Specific Challenges
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Veldhuizen, Maria G., primary, Cecchetto, Cinzia, additional, Fjaeldstad, Alexander W., additional, Farruggia, Michael C., additional, Hartig, Renée, additional, Nakamura, Yuko, additional, Pellegrino, Robert, additional, Yeung, Andy W. K., additional, and Fischmeister, Florian Ph. S., additional
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- 2022
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31. Non-invasive vagus nerve stimulation in a hungry state decreases heart rate variability and wanting of a palatable drink
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Altınkaya, Zeynep, primary, Öztürk, Lina, additional, Büyükgüdük, İlkim, additional, Yanık, Hüseyin, additional, Yılmaz, Dilan Deniz, additional, Yar, Berçem, additional, Değirmenci, Evren, additional, Dal, Uğur, additional, and Veldhuizen, Maria Geraldine, additional
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- 2022
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32. Massively collaborative crowdsourced research on COVID19 and the chemical senses: Insights and outcomes
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Weir, Elisabeth M., primary, Reed, Danielle R., additional, Pepino, M. Yanina, additional, Veldhuizen, Maria G., additional, and Hayes, John E., additional
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- 2022
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33. Verbal descriptors influence hypothalamic response to low-calorie drinks
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Veldhuizen, Maria G., Nachtigal, Danielle J., Flammer, Linda J., de Araujo, Ivan E., and Small, Dana M.
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- 2013
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34. Midbrain response to milkshake correlates with ad libitum milkshake intake in the absence of hunger
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Nolan-Poupart, Sarah, Veldhuizen, Maria G., Geha, Paul, and Small, Dana M.
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- 2013
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35. Mere end lugtesans - COVID-19 er associeret med svær påvirkning af lugtesansen, smagssansen og mundfølelsen
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Parma, Valentina, Ohla, Kathrin, Veldhuizen, Maria G, Niv, Masha Y, Kelly, Christine E, Bakke, Alyssa J, Cooper, Keiland W, Bouysset, Cédric, Pirastu, Nicola, Dibattista, Michele, Kaur, Rishemjit, Liuzza, Marco Tullio, Pepino, Marta Y, Schöpf, Veronika, Pereda-Loth, Veronica, Olsson, Shannon B, Gerkin, Richard C, Rohlfs Domínguez, Paloma, Albayay, Javier, Farruggia, Michael C, Bhutani, Surabhi, Fjaeldstad, Alexander W, Kumar, Ritesh, Menini, Anna, Bensafi, Moustafa, Sandell, Mari, Konstantinidis, Iordanis, Di Pizio, Antonella, Genovese, Federica, Öztürk, Lina, Thomas-Danguin, Thierry, Frasnelli, Johannes, Boesveldt, Sanne, Saatci, Özlem, Saraiva, Luis R, Lin, Cailu, Golebiowski, Jérôme, Hwang, Liang-Dar, Ozdener, Mehmet Hakan, Guàrdia, Maria Dolors, Laudamiel, Christophe, Ritchie, Marina, Havlícek, Jan, Pierron, Denis, Roura, Eugeni, Navarro, Marta, Nolden, Alissa A, Lim, Juyun, Whitcroft, Katherine L, Colquitt, Lauren R, Ferdenzi, Camille, Brindha, Evelyn V, Altundag, Aytug, Macchi, Alberto, Nunez-Parra, Alexia, Patel, Zara M, Fiorucci, Sébastien, Philpott, Carl M, Smith, Barry C, Lundström, Johan N, Mucignat, Carla, Parker, Jane K, van den Brink, Mirjam, Schmuker, Michael, Fischmeister, Florian Ph S, Heinbockel, Thomas, Shields, Vonnie D C, Faraji, Farhoud, Santamaría, Enrique, Fredborg, William E A, Morini, Gabriella, Olofsson, Jonas K, Jalessi, Maryam, Karni, Noam, D’Errico, Anna, Alizadeh, Rafieh, Pellegrino, Robert, Meyer, Pablo, Huart, Caroline, Chen, Ben, Soler, Graciela M, Alwashahi, Mohammed K, Welge-Lüssen, Antje, Freiherr, Jessica, de Groot, Jasper H B, Klein, Hadar, Okamoto, Masako, Singh, Preet Bano, Hsieh, Julien W, Abdulrahman, Olagunju, Dalton, Pamela, Yan, Carol H, Voznessenskaya, Vera V, Chen, Jingguo, Sell, Elizabeth A, Walsh-Messinger, Julie, Archer, Nicholas S, Koyama, Sachiko, Deary, Vincent, Roberts, S Craig, Yanık, Hüseyin, Albayrak, Samet, Nováková, Lenka Martinec, Croijmans, Ilja, Mazal, Patricia Portillo, Moein, Shima T, Margulis, Eitan, Mignot, Coralie, Mariño, Sajidxa, Georgiev, Dejan, Kaushik, Pavan K, Malnic, Bettina, Wang, Hong, Seyed-Allaei, Shima, Yoluk, Nur, Razzaghi-Asl, Sara, Justice, Jeb M, Restrepo, Diego, Reed, Danielle R, Hummel, Thomas, Munger, Steven D, Hayes, John E, Indústries Alimentàries, Qualitat i Tecnologia Alimentària, Tecnologia Alimentària, Temple University [Philadelphia], Pennsylvania Commonwealth System of Higher Education (PCSHE), Forschungszentrum Jülich GmbH | Centre de recherche de Juliers, Helmholtz-Gemeinschaft = Helmholtz Association, Mersin University, The Hebrew University of Jerusalem (HUJ), AbScent, Pennsylvania State University (Penn State), Penn State System, University of California [Irvine] (UC Irvine), University of California (UC), Université Côte d'Azur (UCA), University of Edinburgh, Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro (UNIBA), Central Scientific Instruments Organisation (CSIR), Università degli Studi 'Magna Graecia' di Catanzaro = University of Catanzaro (UMG), University of Illinois at Urbana-Champaign [Urbana], University of Illinois System, Medizinische Universität Wien = Medical University of Vienna, Groupement scientifique de Biologie et de Medecine Spatiale (GSBMS), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National d'Études Spatiales [Toulouse] (CNES), Tata Institute for Fundamental Research (TIFR), Arizona State University [Tempe] (ASU), Universidad de Extremadura - University of Extremadura (UEX), Università degli Studi di Padova = University of Padua (Unipd), Yale School of Medicine [New Haven, Connecticut] (YSM), San Diego State University (SDSU), Aarhus University [Aarhus], University of Hertfordshire [Hatfield] (UH), Scuola Internazionale Superiore di Studi Avanzati / International School for Advanced Studies (SISSA / ISAS), Neurosciences Sensorielles Comportement Cognition, Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Helsingin yliopisto = Helsingfors universitet = University of Helsinki, University of Turku, Aristotle University of Thessaloniki, Leibniz-Institute for Food Systems Biology at the Technical University of Munich, Monell Chemical Senses Center, Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Bourgogne Franche-Comté [COMUE] (UBFC), Université de Montréal (UdeM), Wageningen University and Research Centre (WUR), Medical Science University, Sidra Medicine [Doha, Qatar], Institut de Chimie de Nice (ICN), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), University of Southern Queensland (USQ), Institut de Recerca i Tecnologia Agroalimentàries = Institute of Agrifood Research and Technology (IRTA), DreamAir Llc, Charles University [Prague] (CU), Anthropologie Moléculaire et Imagerie de Synthèse (AMIS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), University of Massachusetts System (UMASS), Oregon State University (OSU), Ear Institute, UCL, Lyon Neuroscience Research center, Karunya University, Biruni University, Assi Sette Llaghi Varese, Stanford School of Medicine [Stanford], Stanford Medicine, Stanford University-Stanford University, University of East Anglia [Norwich] (UEA), California Department of Food and Agriculture (CDFA), Unité mixte de recherche interactions plantes-microorganismes, Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Maastricht University [Maastricht], Institute for Biology - Neurobiology, Freie Universität Berlin, Karl-Franzens-Universität Graz, Howard University College of Medicine, Towson University, University of California [San Diego] (UC San Diego), Proteomics, Center for Applied Medical Research (CIMA), Stockholm University, University of Gastronomic Sciences, Iran University of Medical Sciences, Goethe Universität Frankfurt, University of Tennessee, IBM T.J. Watson Research Center, Université libre de Bruxelles (ULB), Guangzhou Medical University, Buenos Aires University and GEOG (Grupo de Estudio de Olfato y Gusto), Sultan Qaboos University (SQU), Federal University of Technology of Akure (FUTA), A.N. Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences [Moscow] (RAS), Hospital of Xi'an Jiaotong University, University of Pennsylvania, University of Dayton, CSIRO Agriculture and Food (CSIRO), Indiana University [Bloomington], Indiana University System, University of Northumbria at Newcastle [United Kingdom], University of Stirling, Middle East Technical University [Ankara] (METU), Utrecht University [Utrecht], Instituto Universitario del Hospital Italiano [Buenos Aires, Argentina], Institute for Research in Fundamental Sciences [Tehran] (IPM), Hebrew University of Jerusalem, Technische Universität Dresden = Dresden University of Technology (TU Dresden), Terrazas del Club Hipico, University Medical Centre Ljubljana [Ljubljana, Slovenia] (UMCL), Tata Institute of Fundamental Research [Bangalore], Universidade de São Paulo = University of São Paulo (USP), University of Florida [Gainesville] (UF), University of Colorado Anschutz [Aurora], Center for Smell and Taste, Department of Food Science, Pennsylvania State University., Julien, Sabine, Tıp Fakültesi, UCL - SSS/IONS/NEUR - Clinical Neuroscience, UCL - (SLuc) Service d'oto-rhino-laryngologie, Department of Food and Nutrition, Senses and Food, Research Center Jülich, University of California [Irvine] (UCI), University of California, Università degli studi di Bari Aldo Moro (UNIBA), Università degli Studi 'Magna Graecia' di Catanzaro [Catanzaro, Italie] (UMG), University of Extremadura, University of Padova, Yale University School of Medicine, Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, University of Helsinki, Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Institute of Agrifood Research and Technology (IRTA), Universita degli Studi di Padova, Centre National de la Recherche Scientifique (CNRS)-Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Karl-Franzens-Universität [Graz, Autriche], University of California San Diego Health, University of Brussels, University of Pennsylvania [Philadelphia], Tata Institute of Fundamental Research, University of São Paulo (USP), UCL - SSS/IONS - Institute of NeuroScience, FSE Campus Venlo, and RS: FSE UCV
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Male ,Taste ,Physiology ,Smagstab ,Audiology ,AcademicSubjects/SCI01180 ,Settore BIO/09 - Fisiologia ,Behavioral Neuroscience ,chemistry.chemical_compound ,Olfaction Disorders ,Taste Disorders ,0302 clinical medicine ,RATINGS ,Hyposmia ,Surveys and Questionnaires ,CHEMOSENSITIVITY ,[SDV.IDA]Life Sciences [q-bio]/Food engineering ,Viral ,PALADAR ,030223 otorhinolaryngology ,Sensory Science and Eating Behaviour ,media_common ,TASTE ,US NATIONAL-HEALTH ,[SDV.IDA] Life Sciences [q-bio]/Food engineering ,Middle Aged ,Biological Sciences ,16. Peace & justice ,Sensory Systems ,3. Good health ,Smell ,GCCR Group Author ,ddc:540 ,Smell loss ,Female ,Original Article ,medicine.symptom ,Corrigendum ,Coronavirus Infections ,olfaction ,Adult ,somatosensation ,medicine.medical_specialty ,663/664 ,Coronavirus disease 2019 (COVID-19) ,OLFACTORY DISORDERS ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,media_common.quotation_subject ,Pneumonia, Viral ,head and neck surgery ,Aged ,Betacoronavirus ,COVID-19 ,Humans ,Pandemics ,SARS-CoV-2 ,Self Report ,Somatosensory Disorders ,Young Adult ,Anosmia ,Sensory system ,Olfaction ,03 medical and health sciences ,Chemesthesis ,Physiology (medical) ,Perception ,medicine ,Neurology & Neurosurgery ,Behaviour Change and Well-being ,business.industry ,R-PACKAGE ,3112 Neurosciences ,Pneumonia ,Parosmia ,COMPONENT ,Smagssans ,[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition ,Sensoriek en eetgedrag ,chemistry ,Lugtetab ,business ,[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition ,030217 neurology & neurosurgery ,Lugtesans - Abstract
Correction: Chemical Senses, Volume 46, 2021, bjab050, https://doi.org/10.1093/chemse/bjab050 Published: 08 December 2021 Recent anecdotal and scientific reports have provided evidence of a link between COVID-19 and chemosensory impairments, such as anosmia. However, these reports have downplayed or failed to distinguish potential effects on taste, ignored chemesthesis, and generally lacked quantitative measurements. Here, we report the development, implementation, and initial results of a multilingual, international questionnaire to assess self-reported quantity and quality of perception in 3 distinct chemosensory modalities (smell, taste, and chemesthesis) before and during COVID-19. In the first 11 days after questionnaire launch, 4039 participants (2913 women, 1118 men, and 8 others, aged 19-79) reported a COVID-19 diagnosis either via laboratory tests or clinical assessment. Importantly, smell, taste, and chemesthetic function were each significantly reduced compared to their status before the disease. Difference scores (maximum possible change +/- 100) revealed a mean reduction of smell (-79.7 +/- 28.7, mean +/- standard deviation), taste (-69.0 +/- 32.6), and chemesthetic (-37.3 +/- 36.2) function during COVID-19. Qualitative changes in olfactory ability (parosmia and phantosmia) were relatively rare and correlated with smell loss. Importantly, perceived nasal obstruction did not account for smell loss. Furthermore, chemosensory impairments were similar between participants in the laboratory test and clinical assessment groups. These results show that COVID-19-associated chemosensory impairment is not limited to smell but also affects taste and chemesthesis.The multimodal impact of COVID-19 and the lack of perceived nasal obstruction suggest that severe acute respiratory syndrome coronavirus strain 2 (SARS-CoV-2) infection may disrupt sensory-neural mechanisms.
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- 2020
36. Genome-Wide Association Study of Food Liking in 162,000 People Uncovers the Genetic Bases of Food Liking
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May-Wilson, Sebastian, Matoba, Nana, Wade, Kaitlin, Concas, Maria Pina, Hottenga, Jouke-Jan, Mangino, Massimo, Veldhuizen, Maria G., Menni, Cristina, de Geus, Eco, Gasparini, Paolo, Timpson, Nicholas, Wilson, Jim, Pirastu, Nicola, Biological Psychology, APH - Health Behaviors & Chronic Diseases, APH - Personalized Medicine, AMS - Ageing & Vitality, AMS - Sports, and APH - Mental Health
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Food liking ,GWAS ,GenomicSEM - Published
- 2021
37. The best COVID-19 predictor is recent smell loss: a cross-sectional study
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Gerkin, Richard, Ohla, Kathrin, Veldhuizen, Maria Geraldine, Joseph, Paule, Kelly, Christine, Bakke, Alyssa, Steele, Kimberley, Pellegrino, Robert, Pepino, Marta, Bouysset, Cédric, Soler, Graciela, Pereda-Loth, Veronica, Dibattista, Michele, Cooper, Keiland, Croijmans, Ilja, Di Pizio, Antonella, Ozdener, M. Hakan, D'Errico, Anna, Fischmeister, Florian Ph.S, Bock, María Adelaida, Domínguez, Paloma Paloma, Yanık, Hüseyin, Boesveldt, Sanne, de Groot, Jasper, Dinnella, Caterina, Freiherr, Jessica, Laktionova, Tatiana, Mariño, Sajidxa, Monteleone, Erminio, Nunez-Parra, Alexia, Abdulrahman, Olagunju, Ritchie, Marina, Thomas-Danguin, Thierry, Walsh-Messinger, Julie, Al Abri, Rashid, Alizadeh, Rafieh, Bignon, Emmanuelle, Cantone, Elena, Cecchini, Maria Paola, Chen, Jingguo, Guàrdia, Maria Dolors, Hoover, Kara, Karni, Noam, Navarro, Marta, Nolden, Alissa, Mazal, Patricia Portillo, Rowan, Nicholas, Sarabi-Jamab, Atiye, Archer, Nicholas, Chen, Ben, Di Valerio, Elizabeth, Feeney, Emma, Frasnelli, Johannes, Hannum, Mackenzie, Hopkins, Claire, Klein, Hadar, Mignot, Coralie, Mucignat, Carla, Ning, Yuping, Ozturk, Elif, Peng, Mei, Saatci, Ozlem, Sell, Elizabeth, Yan, Carol, Alfaro, Raul, Cecchetto, Cinzia, Coureaud, Gérard, Herriman, Riley, Justice, Jeb, Kaushik, Pavan Kumar, Koyama, Sachiko, Overdevest, Jonathan, Pirastu, Nicola, Ramirez, Vicente, Roberts, S. Craig, Smith, Barry, Cao, Hongyuan, Wang, Hong, Balungwe, Patrick, Baguma, Marius, Veldhuizen, Maria, Farruggia, Michael, Pizio, Antonella, Hakan Ozdener, M, Fjaeldstad, Alexander, Lin, Cailu, Sandell, Mari, Singh, Preet, Brindha, V. Evelyn, Olsson, Shannon, Saraiva, Luis, Ahuja, Gaurav, Alwashahi, Mohammed, Bhutani, Surabhi, Fornazieri, Marco, Golebiowski, Jérôme, Hwang, Liang-Dar, Öztürk, Lina, Roura, Eugeni, Spinelli, Sara, Whitcroft, Katherine, Faraji, Farhoud, Fischmeister, Florian, Heinbockel, Thomas, Hsieh, Julien, Huart, Caroline, Konstantinidis, Iordanis, Menini, Anna, Morini, Gabriella, Olofsson, Jonas, Philpott, Carl, Pierron, Denis, Shields, Vonnie, Voznessenskaya, Vera, Albayay, Javier, Altundag, Aytug, Bensafi, Moustafa, Bock, María, Calcinoni, Orietta, Fredborg, William, Laudamiel, Christophe, Lim, Juyun, Lundström, Johan, Macchi, Alberto, Meyer, Pablo, Moein, Shima, Santamaría, Enrique, Sengupta, Debarka, Rohlfs Dominguez, Paloma, Yanik, Hüseyin, Group, GCCR, Hummel, Thomas, Hayes, John, Reed, Danielle, Niv, Masha, Munger, Steven, Parma, Valentina, Arizona State University [Tempe] (ASU), Institute of Neuroscience and Medicine [Jülich] (INM-1), Mersin University, National Institutes of Health [Bethesda] (NIH), AbScent, Pennsylvania State University (Penn State), Penn State System, National Institute of Diabetes and Digestive and Kidney Diseases [Bethesda], Yale University [New Haven], Tennessee State University, University of Illinois at Urbana-Champaign [Urbana], University of Illinois System, Institut de Chimie de Nice (ICN), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Buenos Aires University and GEOG (Grupo de Estudio de Olfato y Gusto), Anthropologie Moléculaire et Imagerie de Synthèse (AMIS), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), University of Bari Aldo Moro (UNIBA), University of California [Irvine] (UCI), University of California, Utrecht University [Utrecht], Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), Monell Chemical Senses Center, Regional Hospital West Jutland [Denmark], University of Helsinki, University of Oslo (UiO), Karunya University, Tata Institute for Fundamental Research (TIFR), Research at Sidra Medicine Research Branch [Doha, Qatar], Indraprastha Institute of Information Technology [New Delhi] (IIIT-Delhi), Sultan Qaboos University (SQU), San Diego State University (SDSU), Goethe-University Frankfurt am Main, State University of Londrina = Universidade Estadual de Londrina, University of Queensland [Brisbane], Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI), University College of London [London] (UCL), University of Graz, Howard University, Geneva University Hospital (HUG), Cliniques Universitaires Saint-Luc [Bruxelles], Aristotle University of Thessaloniki, Scuola Internazionale Superiore di Studi Avanzati / International School for Advanced Studies (SISSA / ISAS), University of Gastronomic Sciences of Pollenzo (UNISG), Stockholm University, University of East Anglia [Norwich] (UEA), Towson University [Towson, MD, United States], University of Maryland System, A.N. Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences [Moscow] (RAS), Universita degli Studi di Padova, Biruni University, Centre de recherche en neurosciences de Lyon (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Hospital General de Barrio Obrero [Asunción, Paraguay] (Public Hospital Barrio Obrero ), Private practice [Milan], DreamAir Llc, Oregon State University (OSU), Cancer Center Karolinska [Karolinska Institutet] (CCK), Karolinska Institutet [Stockholm], University of Insubria, Varese, Computational Biology Center (IBM T.J. Watson Research Center), IBM, Institute for Research in Fundamental Sciences [Tehran] (IPM), Instituto de Investigación Sanitaria de Navarra [Pamplona, Spain] (IdiSNA), University of Extremadura, Technische Universität Dresden = Dresden University of Technology (TU Dresden), The Hebrew University of Jerusalem (HUJ), University of Florida [Gainesville] (UF), Temple University [Philadelphia], Pennsylvania Commonwealth System of Higher Education (PCSHE), Non-byline authors (to be listed as collaborators in PubMed under the GCCR Group Author): Sanne Boesveldt, Jasper H.B. de Groot, Caterina Dinnella, Jessica Freiherr, Tatiana Laktionova, Sajidxa Mariño, Erminio Monteleone, Alexia Nunez-Parra, Olagunju Abdulrahman, Marina Ritchie, Thierry Thomas-Danguin, Julie Walsh-Messinger, Rashid Al Abri, Rafieh Alizadeh, Emmanuelle Bignon, Elena Cantone, Maria Paola Cecchini, Jingguo Chen, Maria Dolors Guàrdia, Kara C. Hoover, Noam Karni, Marta Navarro, Alissa A. Nolden, Patricia Portillo Mazal, Nicholas R. Rowan, Atiye SarabiJamab, Nicholas S. Archer, Ben Chen, Elizabeth A. Di Valerio, Emma L. Feeney, Johannes Frasnelli, Mackenzie E. Hannum, Claire Hopkins, Hadar Klein, Coralie Mignot, Carla Mucignat, Yuping Ning, Elif E. Ozturk, Mei Peng, Ozlem Saatci, Elizabeth A. Sell, Carol H. Yan, Raul Alfaro, Cinzia Cecchetto, Gérard Coureaud, Riley D. Herriman, Jeb M. Justice, Pavan Kumar Kaushik, Sachiko Koyama, Jonathan B. Overdevest, Nicola Pirastu, Vicente A. Ramirez, S. Craig Roberts, Barry C. Smith, Hongyuan Cao, Hong Wang, Patrick Balungwe Birindwa, Marius Baguma, Karl-Franzens-Universität [Graz, Autriche], Forschungszentrum Jülich GmbH | Centre de recherche de Juliers, Helmholtz-Gemeinschaft = Helmholtz Association, The Pennsylvania State University, University of Tennessee, University of Buenos Aires [Argentina], Università degli studi di Bari Aldo Moro (UNIBA), Goethe University of Frankfurt am Main, Wageningen University and Research [Wageningen] (WUR), Radboud university [Nijmegen], Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), A.N. Severtsov Institute of Ecology and Evolution RAS, 119071, Russia., RespiraLibre - Centro de Otorrinolaringología, Department of Agriculture, Food, Environment and Forestry (DAGRI), University of Florence, Partenaires INRAE, Universidad de Chile = University of Chile [Santiago] (UCHILE), Federal University of Technology of Akure (FUTA), Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Bourgogne Franche-Comté [COMUE] (UBFC), University of Dayton, Iran University of Medical Sciences, University of Naples Federico II, University of Verona (UNIVR), Head and Neck Surgery, Hospital of Xi'an Jiaotong University, Institute of Agrifood Research and Technology (IRTA), University of Alaska [Fairbanks] (UAF), Hadassah Hebrew University Medical Center [Jerusalem], University of Southern Queensland (USQ), University of Massachusetts, Instituto Universitario del Hospital Italiano [Buenos Aires, Argentina], Johns Hopkins University School of Medicine [Baltimore], Commonwealth Scientific and Industrial Research Organisation [Canberra] (CSIRO), The First Affiliated Hospital of Guangzhou Medical University (GMU), University College Dublin [Dublin] (UCD), Université du Québec à Trois-Rivières (UQTR), Guy's and St Thomas' Hospitals, University of Padova [Padova, Italy], Kilis Yedi Aralik University, University of Otago [Dunedin, Nouvelle-Zélande], Sancaktepe Education and Research Hospital, Hospital of the University of Pennsylvania (HUP), Perelman School of Medicine, University of Pennsylvania [Philadelphia]-University of Pennsylvania [Philadelphia], UC San Diego Health, University ofFlorida, Tata Institute of Fundamental Research, Indiana University [Bloomington], Indiana University System, Columbia University Irving Medical Center (CUIMC), University of Edinburgh, University of California [Merced], University of Stirling, University of London [London], Florida State University [Panama City], Université catholique de Bukavu, Leibniz-Institute for Food Systems Biology at the Technical University of Munich, Karunya Institute of Technology and Sciences, Sidra Medicine, School of Exercise and Nutritional Sciences, Howard University College of Medicine, Geneva University Hospitals, Geneva University , Geneva , Switzerland., CHU Genève, General Hospital Papageorgiou, University of Toulouse, University of Padova, Lyon Neuroscience Research center, IBM T.J. Watson Research Center, Navarrabiomed-IdiSNA, Temple University, Julien, Sabine, Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Universitad de Buenos Aires = University of Buenos Aires [Argentina], Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro (UNIBA), University of California [Irvine] (UC Irvine), University of California (UC), Karl-Franzens-Universität Graz, Universidad de Extremadura - University of Extremadura (UEX), Radboud University [Nijmegen], Università degli Studi di Firenze = University of Florence (UniFI), University of Naples Federico II = Università degli studi di Napoli Federico II, Università degli studi di Verona = University of Verona (UNIVR), Institut de Recerca i Tecnologia Agroalimentàries = Institute of Agrifood Research and Technology (IRTA), Università degli Studi di Padova = University of Padua (Unipd), University of Pennsylvania-University of Pennsylvania, School of Medicine [Univ California San Diego] (UC San Diego), University of California [San Diego] (UC San Diego), University of California (UC)-University of California (UC)-University of California [San Diego] (UC San Diego), University of California (UC)-University of California (UC), Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center (CRNL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Tata Institute of Fundamental Research [Bangalore], University of California [Merced] (UC Merced), Helsingin yliopisto = Helsingfors universitet = University of Helsinki, Sidra Medicine [Doha, Qatar], Universitá degli Studi dell’Insubria = University of Insubria [Varese] (Uninsubria), and Universitá degli Studi dell’Insubria
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Adult ,Male ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Cross-sectional study ,Visual analogue scale ,Anosmia ,Audiology ,Logistic regression ,AcademicSubjects/SCI01180 ,Article ,Odds ,03 medical and health sciences ,0302 clinical medicine ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Hyposmia ,Humans ,Medicine ,[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs ,030223 otorhinolaryngology ,SARS-CoV-2 ,business.industry ,[SCCO.NEUR]Cognitive science/Neuroscience ,COVID-19 ,Middle Aged ,Prognosis ,Smell ,[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition ,Cross-Sectional Studies ,[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organs ,Smell loss ,[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Female ,Original Article ,Self Report ,medicine.symptom ,business ,[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition ,030217 neurology & neurosurgery ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
BackgroundCOVID-19 has heterogeneous manifestations, though one of the most common symptoms is a sudden loss of smell (anosmia or hyposmia). We investigated whether olfactory loss is a reliable predictor of COVID-19.MethodsThis preregistered, cross-sectional study used a crowdsourced questionnaire in 23 languages to assess symptoms in individuals self-reporting recent respiratory illness. We quantified changes in chemosensory abilities during the course of the respiratory illness using 0-100 visual analog scales (VAS) for participants reporting a positive (C19+; n=4148) or negative (C19-; n=546) COVID-19 laboratory test outcome. Logistic regression models identified singular and cumulative predictors of COVID-19 status and post-COVID-19 olfactory recovery.ResultsBoth C19+ and C19-groups exhibited smell loss, but it was significantly larger in C19+ participants (mean±SD, C19+: -82.5±27.2 points; C19-: -59.8±37.7). Smell loss during illness was the best predictor of COVID-19 in both single and cumulative feature models (ROC AUC=0.72), with additional features providing negligible model improvement. VAS ratings of smell loss were more predictive than binary chemosensory yes/no-questions or other cardinal symptoms, such as fever or cough. Olfactory recovery within 40 days was reported for ∼50% of participants and was best predicted by time since illness onset.ConclusionsAs smell loss is the best predictor of COVID-19, we developed the ODoR-19 tool, a 0-10 scale to screen for recent olfactory loss. Numeric ratings ≤2 indicate high odds of symptomatic COVID-19 (4
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- 2020
38. One Year Follow-Up of Taste-Related Reward Associations with Weight Loss Suggests a Critical Time to Mitigate Weight Regain Following Bariatric Surgery
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Smith, Kimberly R., primary, Aghababian, Anahys, additional, Papantoni, Afroditi, additional, Veldhuizen, Maria G., additional, Kamath, Vidyulata, additional, Harris, Civonnia, additional, Moran, Timothy H., additional, Carnell, Susan, additional, and Steele, Kimberley E., additional
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- 2021
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39. Massively collaborative crowdsourced research on COVID19 and the chemical senses
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Weir, Elisabeth, primary, Reed, Danielle, additional, Pepino, M. Yanina, additional, Veldhuizen, Maria, additional, and Hayes, John, additional
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- 2021
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40. Weighing the evidence: Variance in brain responses to milkshake receipt is predictive of eating behavior
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Kroemer, Nils B., Sun, Xue, Veldhuizen, Maria G., Babbs, Amanda E., de Araujo, Ivan E., and Small, Dana M.
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- 2016
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41. Perceptual and Brain Response to Odors Is Associated with Body Mass Index and Postprandial Total Ghrelin Reactivity to a Meal
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Sun, Xue, Veldhuizen, Maria G., Babbs, Amanda E., Sinha, Rajita, and Small, Dana M.
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- 2016
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42. Flavor Identification and Intensity: Effects of Stimulus Context
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Hallowell, Emily S., Parikh, Roshan, Veldhuizen, Maria G., and Marks, Lawrence E.
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- 2016
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43. Response Times to Gustatory–Olfactory Flavor Mixtures: Role of Congruence
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Shepard, Timothy G., Veldhuizen, Maria G., and Marks, Lawrence E.
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- 2015
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44. Recent Smell Loss Is the Best Predictor of COVID-19 Among Individuals With Recent Respiratory Symptoms
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Gerkin, Richard, Ohla, Kathrin, Veldhuizen, Maria, Joseph, Paule, Kelly, Christine, Bakke, Alyssa, Steele, Kimberley, Farruggia, Michael, Pellegrino, Robert, Pepino, Marta, Bouysset, Cédric, Soler, Graciela, Pereda-Loth, Veronica, Dibattista, Michele, Cooper, Keiland, Croijmans, Ilja, Di Pizio, Antonella, Ozdener, Mehmet Hakan, Fjaeldstad, Alexander, Lin, Cailu, Sandell, Mari, Singh, Preet, Brindha, Evelyn, Olsson, Shannon, Saraiva, Luis, Ahuja, Gaurav, Alwashahi, Mohammed, Bhutani, Surabhi, D’Errico, Anna, Fornazieri, Marco, Golebiowski, Jérôme, Dar Hwang, Liang, Öztürk, Lina, Roura, Eugeni, Spinelli, Sara, Whitcroft, Katherine, Faraji, Farhoud, Fischmeister, Florian, Heinbockel, Thomas, Hsieh, Julien, Huart, Caroline, Konstantinidis, Iordanis, Menini, Anna, Morini, Gabriella, Olofsson, Jonas, Philpott, Carl, Pierron, Denis, Shields, Vonnie, Voznessenskaya, Vera, Albayay, Javier, Altundag, Aytug, Bensafi, Moustafa, Bock, María Adelaida, Calcinoni, Orietta, Fredborg, William, Laudamiel, Christophe, Lim, Juyun, Lundström, Johan, Macchi, Alberto, Meyer, Pablo, Moein, Shima, Santamaría, Enrique, Sengupta, Debarka, Rohlfs Dominguez, Paloma, Yanik, Hüseyin, Hummel, Thomas, Hayes, John, Reed, Danielle, Niv, Masha, Munger, Steven, Parma, Valentina, Boesveldt, Sanne, de Groot, Jasper, Dinnella, Caterina, Freiherr, Jessica, Laktionova, Tatiana, Marino, Sajidxa, Monteleone, Erminio, Nunez-Parra, Alexia, Abdulrahman, Olagunju, Ritchie, Marina, Thomas-Danguin, Thierry, Walsh-Messinger, Julie, Al Abri, Rashid, Alizadeh, Rafieh, Bignon, Emmanuelle, Cantone, Elena, Paola Cecchini, Maria, Chen, Jingguo, Dolors Guàrdia, Maria, Hoover, Kara, Karni, Noam, Navarro, Marta, Nolden, Alissa, Portillo Mazal, Patricia, Rowan, Nicholas, Sarabi-Jamab, Atiye, Archer, Nicholas, Chen, Ben, Di Valerio, Elizabeth, Feeney, Emma, Frasnelli, Johannes, Hannum, Mackenzie, Hopkins, Claire, Klein, Hadar, Mignot, Coralie, Mucignat, Carla, Ning, Yuping, Ozturk, Elif, Peng, Mei, Saatci, Ozlem, Sell, Elizabeth, Yan, Carol, Alfaro, Raul, Coureaud, G., Herriman, Riley, Justice, Jeb, Kaushik, Pavan Kumar, Koyama, Sachiko, Overdevest, Jonathan, Pirastu, Nicola, Ramirez, Vicente, Roberts, S. Craig, Smith, Barry, Cao, Hongyuan, Wang, Hong, Balungwe Birindwa, Patrick, Baguma, Marius, Ozdener, Mehmet, Bock, María, Kaushik, Pavan, Pizio, Antonella, Hakan Ozdener, Mehmet, D'Errico, Anna, Hwang, Liang Dar, Group, GCCR, Cecchini, Maria, Indústries Alimentàries, Qualitat i Tecnologia Alimentària, Arizona State University [Tempe] (ASU), Forschungszentrum Jülich GmbH | Centre de recherche de Juliers, Helmholtz-Gemeinschaft = Helmholtz Association, Mersin University, National Institutes of Health [Bethesda] (NIH), AbScent, Pennsylvania State University (Penn State), Penn State System, Yale University [New Haven], University of Tennessee, University of Illinois at Urbana-Champaign [Urbana], University of Illinois System, Institut de Chimie de Nice (ICN), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Buenos Aires University and GEOG (Grupo de Estudio de Olfato y Gusto), Centre d'anthropologie et de génomique de Toulouse (CAGT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Università degli studi di Bari Aldo Moro (UNIBA), University of California, Utrecht University [Utrecht], Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), Monell Chemical Senses Center, Regional Hospital West Jutland [Denmark], University of Helsinki, University of Oslo (UiO), Karunya Institute of Technology and Sciences, Tata Institute of Fundamental Research, Sidra Medicine [Doha, Qatar], Indraprastha Institute of Information Technology [New Delhi] (IIIT-Delhi), Sultan Qaboos University (SQU), San Diego State University (SDSU), Goethe-University Frankfurt am Main, State University of Londrina = Universidade Estadual de Londrina, Elena Cantone, University of Queensland - The Diamantina Institute, University of Queensland [Brisbane], Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI), University College of London [London] (UCL), UC San Diego Health, Karl-Franzens-Universität [Graz, Autriche], Howard University College of Medicine [Washington, DC, USA], Geneva University Hospitals and Geneva University, Cliniques Universitaires Saint-Luc [Bruxelles], Aristotle University of Thessaloniki, Scuola Internazionale Superiore di Studi Avanzati / International School for Advanced Studies (SISSA / ISAS), Stockholm University, University of East Anglia [Norwich] (UEA), Towson University [Towson, MD, United States], University of Maryland System, Severtsov Institute of Ecology and Evolution RAS, University of Padova [Padova, Italy], Biruni University, Centre de recherche en neurosciences de Lyon (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Hospital General de Barrio Obrero [Asunción, Paraguay] (Public Hospital Barrio Obrero ), Private practice [Milan], DreamAir Llc, Oregon State University (OSU), Karolinska Institutet [Stockholm], University of Insubria, Varese, IBM Watson Research Center, IBM, Navarrabiomed-IdiSNA, University of Extremadura, Technische Universität Dresden = Dresden University of Technology (TU Dresden), The Hebrew University of Jerusalem (HUJ), University of Florida [Gainesville] (UF), Temple University [Philadelphia], Pennsylvania Commonwealth System of Higher Education (PCSHE), Wageningen University and Research [Wageningen] (WUR), Radboud university [Nijmegen], Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Universidad de Chile = University of Chile [Santiago] (UCHILE), Federal University of Technology of Akure (FUTA), University of California [Berkeley], Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Bourgogne Franche-Comté [COMUE] (UBFC), University of Dayton, Iran University of Medical Sciences [Tehran, Iran] (IUMS), 'Federico II' University of Naples Medical School, University of Verona (UNIVR), Xi'an Jiaotong University (Xjtu), Institute of Agrifood Research and Technology (IRTA), University of Alaska [Fairbanks] (UAF), The Hebrew University Medical Center, University of Massachusetts System (UMASS), Instituto Universitario del Hospital Italiano [Buenos Aires, Argentina], Johns Hopkins University School of Medicine [Baltimore], Institute for Research in Fundamental Sciences [Tehran] (IPM), CSIRO Agriculture and Food (CSIRO), The First Affiliated Hospital of Guangzhou Medical University (GMU), University College Dublin [Dublin] (UCD), Université du Québec à Trois-Rivières (UQTR), Guy’s and St. Thomas’ Hospitals, University of Padova, Kilis Yedi Aralik University, University of Otago [Dunedin, Nouvelle-Zélande], Sancaktepe Education and Research Hospital, University of Pennsylvania [Philadelphia], University of California San Diego Health, Indiana University [Bloomington], Indiana University System, Columbia University Medical Center (CUMC), Columbia University [New York], University of Edinburgh, University of California [Merced], University of Stirling, University of London [London], Florida State University [Tallahassee] (FSU), Université catholique de Bukavu, University of Southern Queensland (USQ), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Technical University of Munich (TUM), University of Graz, Publica, Gerkin, Richard C, Ohla, Kathrin, Veldhuizen, Maria G, Joseph, Paule V, Kelly, Christine E, Bakke, Alyssa J, Steele, Kimberley E, Farruggia, Michael C, Pellegrino, Robert, Pepino, Marta Y, Bouysset, Cédric, Soler, Graciela M, Pereda-Loth, Veronica, Dibattista, Michele, Cooper, Keiland W, Croijmans, Ilja, Di Pizio, Antonella, Ozdener, M Hakan, Fjaeldstad, Alexander W, Lin, Cailu, Sandell, Mari A, Singh, Preet B, Brindha, V Evelyn, Olsson, Shannon B, Saraiva, Luis R, Ahuja, Gaurav, Alwashahi, Mohammed K, Bhutani, Surabhi, D'Errico, Anna, Fornazieri, Marco A, Golebiowski, Jérôme, Hwang, Liang-Dar, Öztürk, Lina, Roura, Eugeni, Spinelli, Sara, Whitcroft, Katherine L, Faraji, Farhoud, Fischmeister, Florian PhS, Heinbockel, Thoma, Hsieh, Julien W, Huart, Caroline, Konstantinidis, Iordani, Menini, Anna, Morini, Gabriella, Olofsson, Jonas K, Philpott, Carl M, Pierron, Deni, Shields, Vonnie D C, Voznessenskaya, Vera V, Albayay, Javier, Altundag, Aytug, Bensafi, Moustafa, Bock, María Adelaida, Calcinoni, Orietta, Fredborg, William, Laudamiel, Christophe, Lim, Juyun, Lundström, Johan N, Macchi, Alberto, Meyer, Pablo, Moein, Shima T, Santamaría, Enrique, Sengupta, Debarka, Dominguez, Paloma Rohlf, Yanik, Hüseyin, Hummel, Thoma, Hayes, John E, Reed, Danielle R, Niv, Masha Y, Munger, Steven D, Parma, Valentina, Tıp Fakültesi, UCL - SSS/IONS/NEUR - Clinical Neuroscience, and UCL - (SLuc) Service d'oto-rhino-laryngologie
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Male ,Multivariate statistics ,Physiology ,Cross-sectional study ,[SDV]Life Sciences [q-bio] ,coronavirus ,Logistic regression ,Settore BIO/09 - Fisiologia ,Behavioral Neuroscience ,0302 clinical medicine ,Hyposmia ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Medicine ,030223 otorhinolaryngology ,Sensory Science and Eating Behaviour ,Chemosensory ,hyposmia ,Middle Aged ,Prognosis ,olfactory ,Sensory Systems ,Smell ,chemosensory ,ddc:540 ,[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] ,Female ,HEALTH ,medicine.symptom ,Adult ,medicine.medical_specialty ,Anosmia ,Coronavirus ,Olfactory ,Prediction ,COVID-19 ,Cross-Sectional Studies ,Humans ,SARS-CoV-2 ,Self Report ,663/664 ,Visual analogue scale ,Odds ,03 medical and health sciences ,Physiology (medical) ,Internal medicine ,QUALITY ,[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs ,COVID-19 symptoms ,Behaviour Change and Well-being ,IDENTIFICATION ,business.industry ,Univariate ,prediction ,Sensoriek en eetgedrag ,business ,030217 neurology & neurosurgery ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology ,anosmia ,Smell impairment - Abstract
Contains fulltext : 228204.pdf (Publisher’s version ) (Closed access) In a preregistered, cross-sectional study we investigated whether olfactory loss is a reliable predictor of COVID-19 using a crowdsourced questionnaire in 23 languages to assess symptoms in individuals self-reporting recent respiratory illness. We quantified changes in chemosensory abilities during the course of the respiratory illness using 0-100 visual analog scales (VAS) for participants reporting a positive (C19+; n=4148) or negative (C19-; n=546) COVID-19 laboratory test outcome. Logistic regression models identified univariate and multivariate predictors of COVID-19 status and post-COVID-19 olfactory recovery. Both C19+ and C19- groups exhibited smell loss, but it was significantly larger in C19+ participants (mean±SD, C19+: -82.5±27.2 points; C19-: -59.8±37.7). Smell loss during illness was the best predictor of COVID-19 in both univariate and multivariate models (ROC AUC=0.72). Additional variables provide negligible model improvement. VAS ratings of smell loss were more predictive than binary chemosensory yes/no-questions or other cardinal symptoms (e.g., fever). Olfactory recovery within 40 days of respiratory symptom onset was reported for ~50% of participants and was best predicted by time since respiratory symptom onset. We find that quantified smell loss is the best predictor of COVID-19 amongst those with symptoms of respiratory illness. To aid clinicians and contact tracers in identifying individuals with a high likelihood of having COVID-19, we propose a novel 0-10 scale to screen for recent olfactory loss, the ODoR-19. We find that numeric ratings ≤2 indicate high odds of symptomatic COVID-19 (4
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- 2020
45. Increasing incidence of parosmia and phantosmia in patients recovering from COVID-19 smell loss
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Ohla, Kathrin, primary, Veldhuizen, Maria Geraldine, additional, Green, Tomer, additional, Hannum, Mackenzie E., additional, Bakke, Alyssa J., additional, Moein, Shima T., additional, Tognetti, Arnaud, additional, Postma, Elbrich M., additional, Pellegrino, Robert, additional, Hwang, Liang-Dar, additional, Albayay, Javier, additional, Koyama, Sachiko, additional, Nolden, Alissa, additional, Thomas-Danguin, Thierry, additional, Mucignat-Caretta, Carla, additional, Menger, Nick S., additional, Croijmans, Ilja, additional, Öztürk, Lina, additional, Yanık, Hüseyin, additional, Pierron, Denis, additional, Pereda-Loth, Veronica, additional, Nunez-Parra, Alexia, additional, Pineda, Aldair M. Martinez, additional, Gillespie, David, additional, Farruggia, Michael C., additional, Cecchetto, Cinzia, additional, Fornazieri, Marco A., additional, Philpott, Carl, additional, Voznessenskaya, Vera, additional, Cooper, Keiland, additional, Dominguez, Paloma Rohlfs, additional, Calcinoni, Orietta, additional, de Groot, Jasper, additional, Boesveldt, Sanne, additional, Bhutani, Surabhi, additional, Weir, Elisabeth M., additional, Exten, Cara, additional, Joseph, Paule V., additional, Parma, Valentina, additional, Hayes, John E., additional, and Niv, Masha Y., additional
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- 2021
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46. Large-scale genome-wide association study of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits
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May-Wilson, Sebastian, primary, Matoba, Nana, additional, Wade, Kaitlin, additional, Hottenga, Jouke-Jan, additional, Concas, Maria Pina, additional, Mangino, Massimo, additional, Grzeszkowiak, Eryk J., additional, Menni, Cristina, additional, Gasparini, Paolo, additional, Timpson, Nicholas J., additional, Veldhuizen, Maria G., additional, de Geus, Eco, additional, Wilson, James F., additional, and Pirastu, Nicola, additional
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- 2021
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47. Non-Weird Human Chemosensory Science
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Veldhuizen, Maria G. and Parma, Valentina
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Öz bulunamadı.
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- 2021
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48. Corrigendum to: More than smell: COVID-19 is associated with severe impairment of smell, taste, and chemesthesis
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Parma, Valentina, Ohla, Kathrin, Veldhuizen, Maria G., Niv, Masha Y., Kelly, Christine E., Bakke, Alyssa J., Cooper, Keiland W., Bouysset, Cédric, Pirastu, Nicola, Dibattista, Michele, Kaur, Rishemjit, Liuzza, Marco Tullio, Pepino, Marta Y., Schöpf, Veronika, Pereda-Loth, Veronica, Olsson, Shannon B., Gerkin, Richard C., Rohlfs Domínguez, Paloma, Albayay, Javier, Farruggia, Michael C., Bhutani, Surabhi, Fjaeldstad, Alexander W., Kumar, Ritesh, Menini, Anna, Bensafi, Moustafa, Sandell, Mari, Konstantinidis, Iordanis, Di Pizio, Antonella, Genovese, Federica, Öztürk, Lina, Thomas-Danguin, Thierry, Frasnelli, Johannes, Boesveldt, Sanne, Saatci, Özlem, Saraiva, Luis R., Lin, Cailu, Golebiowski, Jérôme, Hwang, Liang Dar, Ozdener, Mehmet Hakan, Guàrdia, Maria Dolors, Laudamiel, Christophe, Ritchie, Marina, Havlícek, Jan, Pierron, Denis, Roura, Eugeni, Navarro, Marta, Nolden, Alissa A., Lim, Juyun, Whitcroft, Katherine L., Colquitt, Lauren R., Ferdenzi, Camille, Brindha, Evelyn V., Altundag, Aytug, Macchi, Alberto, Nunez-Parra, Alexia, Patel, Zara M., Fiorucci, Sébastien, Philpott, Carl M., Smith, Barry C., Lundström, Johan N., Mucignat, Carla, Parker, Jane K., Van Den Brink, Mirjam, Schmuker, Michael, Fischmeister, Florian Ph S., Heinbockel, Thomas, Shields, Vonnie D.C., Faraji, Farhoud, Santamaría, Enrique, Fredborg, William E.A., Morini, Gabriella, Olofsson, Jonas K., Jalessi, Maryam, Karni, Noam, D'Errico, Anna, Alizadeh, Rafieh, Pellegrino, Robert, Meyer, Pablo, Huart, Caroline, Chen, Ben, Soler, Graciela M., Alwashahi, Mohammed K., Welge-Lüssen, Antje, Freiherr, Jessica, De Groot, Jasper H.B., Klein, Hadar, Okamoto, Masako, Singh, Preet Bano, Hsieh, Julien W., Abdulrahman, Olagunju, Dalton, Pamela, Yan, Carol H., Voznessenskaya, Vera V., Chen, Jingguo, Sell, Elizabeth A., Walsh-Messinger, Julie, Archer, Nicholas S., Koyama, Sachiko, Deary, Vincent, Roberts, S.C., Yanlk, Hüseyin, Albayrak, Samet, Nováková, Lenka Martinec, Croijmans, Ilja, Mazal, Patricia Portillo, Moein, Shima T., Margulis, Eitan, Mignot, Coralie, Mariño, Sajidxa, Georgiev, Dejan, Kaushik, Pavan K., Malnic, Bettina, Wang, Hong, Seyed-Allaei, Shima, Yoluk, Nur, Razzaghi-Asl, Sara, Justice, Jeb M., Restrepo, Diego, Reed, Danielle R., Hummel, Thomas, Munger, Steven D., Hayes, John E., UCL - SSS/IONS - Institute of NeuroScience, UCL - SSS/IONS/NEUR - Clinical Neuroscience, and UCL - (SLuc) Service d'oto-rhino-laryngologie
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Behavioral Neuroscience ,Sensoriek en eetgedrag ,Behaviour Change and Well-being ,Physiology ,Physiology (medical) ,ddc:540 ,Life Science ,Sensory Systems ,Sensory Science and Eating Behaviour ,VLAG - Abstract
This is a correction notice for article bjaa041 (DOI: https:// doi.org/10.1093/chemse/bjaa041), published 20 June 2020. An incorrect version of the caption to Figure 5 was mistakenly included in the published paper. An updated version is given below. Neither the data nor the paper's conclusions were affected by this correction. The authors sincerely apologize for the error. (A) Correlations between the 3 principal components with respect to changes in 3 chemosensory modalities (i.e., taste, smell, and chemesthesis). Shades of gray indicate positive correlation, whereas shades of red indicate negative correlations. White denotes no correlation. (B) Clusters of participants identified by k-means clustering. The scatterplot shows each participant's loading on dimension 1 (degree of smell and taste loss, PC1 on x-Axis) and dimension 2 (degree of chemesthesis loss, PC2 on y-Axis). Based on the centroid of each cluster, participants in cluster 1 (blue, N = 1767; top left) are generally characterized by significant smell, taste and chemesthesis loss. Participants in cluster 2 (orange, N = 1724; bottom center) are generally characterized by ratings that reflect smell/taste loss with preserved chemesthesis. Loadings for participants in cluster 3 (green, N = 548; right side) are generally characterized by reduced smell and taste loss, and preserved chemesthesis.
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- 2021
49. An fMRI Study of the Interactions Between the Attention and the Gustatory Networks
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Veldhuizen, Maria G., Gitelman, Darren R., and Small, Dana M.
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- 2012
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50. International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020)
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Farmer, Adam D., primary, Strzelczyk, Adam, additional, Finisguerra, Alessandra, additional, Gourine, Alexander V., additional, Gharabaghi, Alireza, additional, Hasan, Alkomiet, additional, Burger, Andreas M., additional, Jaramillo, Andrés M., additional, Mertens, Ann, additional, Majid, Arshad, additional, Verkuil, Bart, additional, Badran, Bashar W., additional, Ventura-Bort, Carlos, additional, Gaul, Charly, additional, Beste, Christian, additional, Warren, Christopher M., additional, Quintana, Daniel S., additional, Hämmerer, Dorothea, additional, Freri, Elena, additional, Frangos, Eleni, additional, Tobaldini, Eleonora, additional, Kaniusas, Eugenijus, additional, Rosenow, Felix, additional, Capone, Fioravante, additional, Panetsos, Fivos, additional, Ackland, Gareth L., additional, Kaithwas, Gaurav, additional, O'Leary, Georgia H., additional, Genheimer, Hannah, additional, Jacobs, Heidi I. L., additional, Van Diest, Ilse, additional, Schoenen, Jean, additional, Redgrave, Jessica, additional, Fang, Jiliang, additional, Deuchars, Jim, additional, Széles, Jozsef C., additional, Thayer, Julian F., additional, More, Kaushik, additional, Vonck, Kristl, additional, Steenbergen, Laura, additional, Vianna, Lauro C., additional, McTeague, Lisa M., additional, Ludwig, Mareike, additional, Veldhuizen, Maria G., additional, De Couck, Marijke, additional, Casazza, Marina, additional, Keute, Marius, additional, Bikson, Marom, additional, Andreatta, Marta, additional, D'Agostini, Martina, additional, Weymar, Mathias, additional, Betts, Matthew, additional, Prigge, Matthias, additional, Kaess, Michael, additional, Roden, Michael, additional, Thai, Michelle, additional, Schuster, Nathaniel M., additional, Montano, Nicola, additional, Hansen, Niels, additional, Kroemer, Nils B., additional, Rong, Peijing, additional, Fischer, Rico, additional, Howland, Robert H., additional, Sclocco, Roberta, additional, Sellaro, Roberta, additional, Garcia, Ronald G., additional, Bauer, Sebastian, additional, Gancheva, Sofiya, additional, Stavrakis, Stavros, additional, Kampusch, Stefan, additional, Deuchars, Susan A., additional, Wehner, Sven, additional, Laborde, Sylvain, additional, Usichenko, Taras, additional, Polak, Thomas, additional, Zaehle, Tino, additional, Borges, Uirassu, additional, Teckentrup, Vanessa, additional, Jandackova, Vera K., additional, Napadow, Vitaly, additional, and Koenig, Julian, additional
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- 2021
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