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Your search keyword '"Vasseur, Loïc"' showing total 18 results
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18 results on '"Vasseur, Loïc"'

1. Early lymphocyte reconstitution and viral infections in adolescents and adults transplanted for sickle cell disease

Author

Vasseur, Loïc, Cuffel, Alexis, Pondarré, Corinne, Dalle, Jean-Hugues, Chevillon, Florian, Fourmont, Aude-Marie, Flamarion, Edouard, Yakouben, Karima, Guérin-El Khourouj, Valérie, Morin, Florence, Ibanez, Clara, Peffault de Latour, Régis, Boissel, Nicolas, Arlet, Jean-Benoit, Moins-Teisserenc, Hélène, Caillat-Zucman, Sophie, and Dhédin, Nathalie

Published
2024
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2. Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients

Author

Halik, Adriane, Tilgner, Marlon, Silva, Patricia, Estrada, Natalia, Altwasser, Robert, Jahn, Ekaterina, Heuser, Michael, Hou, Hsin-An, Pratcorona, Marta, Hills, Robert K., Metzeler, Klaus H., Fenwarth, Laurene, Dolnik, Anna, Terre, Christine, Kopp, Klara, Blau, Olga, Szyska, Martin, Christen, Friederike, Krönke, Jan, Vasseur, Loïc, Löwenberg, Bob, Esteve, Jordi, Valk, Peter J. M., Duchmann, Matthieu, Chou, Wen-Chien, Linch, David C., Döhner, Hartmut, Gale, Rosemary E., Döhner, Konstanze, Bullinger, Lars, Yoshida, Kenichi, and Damm, Frederik

Published
2024
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3. NGS-based stratification refines the risk stratification in T-ALL and identifies a very-high-risk subgroup of patients

Author

Simonin, Mathieu, Vasseur, Loïc, Lengliné, Etienne, Lhermitte, Ludovic, Cabannes-Hamy, Aurélie, Balsat, Marie, Schmidt, Aline, Dourthe, Marie-Emilie, Touzart, Aurore, Graux, Carlos, Grardel, Nathalie, Cayuela, Jean-Michel, Arnoux, Isabelle, Gandemer, Virginie, Huguet, Françoise, Ducassou, Stéphane, Lhéritier, Véronique, Chalandon, Yves, Ifrah, Norbert, Dombret, Hervé, Macintyre, Elizabeth, Petit, Arnaud, Rousselot, Philippe, Lambert, Jérôme, Baruchel, André, Boissel, Nicolas, and Asnafi, Vahid

Published
2024
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4. LSC17 score complements genetics and measurable residual disease in acute myeloid leukemia: an ALFA study

Author

Vasseur, Loïc, Fenwarth, Laurène, Lambert, Jérôme, de Botton, Stéphane, Figeac, Martin, Villenet, Céline, Heiblig, Maël, Dumas, Pierre-Yves, Récher, Christian, Berthon, Céline, Lemasle, Emilie, Lebon, Delphine, Lambert, Juliette, Terré, Christine, Celli-Lebras, Karine, Dombret, Hervé, Preudhomme, Claude, Cheok, Meyling, Itzykson, Raphael, and Duployez, Nicolas

Published
2023
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5. UBTF tandem duplications define a distinct subtype of adult de novo acute myeloid leukemia

Author

Duployez, Nicolas, primary, Vasseur, Loïc, additional, Kim, Rathana, additional, Largeaud, Laëtitia, additional, Passet, Marie, additional, L’Haridon, Anaïs, additional, Lemaire, Pierre, additional, Fenwarth, Laurène, additional, Geffroy, Sandrine, additional, Helevaut, Nathalie, additional, Celli‑Lebras, Karine, additional, Adès, Lionel, additional, Lebon, Delphine, additional, Berthon, Céline, additional, Marceau-Renaut, Alice, additional, Cheok, Meyling, additional, Lambert, Juliette, additional, Récher, Christian, additional, Raffoux, Emmanuel, additional, Micol, Jean-Baptiste, additional, Pigneux, Arnaud, additional, Gardin, Claude, additional, Delabesse, Eric, additional, Soulier, Jean, additional, Hunault, Mathilde, additional, Dombret, Hervé, additional, Itzykson, Raphael, additional, Clappier, Emmanuelle, additional, and Preudhomme, Claude, additional

Published
2023
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6. Prognostic Impact of Monoallelic Versus Biallelic TP53 Alterations in Intensively-Treated Adults AML Patients: A Retrospective Study from the ALFA Group

Author

Fenwarth, Laurène, primary, Vasseur, Loïc, additional, Duployez, Nicolas, additional, Gardin, Claude, additional, Terré, Christine, additional, Lambert, Juliette, additional, de Botton, Stéphane, additional, Celli-Lebras, Karine, additional, Turlure, Pascal, additional, Cluzeau, Thomas, additional, Braun, Thorsten, additional, Thomas, Xavier, additional, Recher, Christian, additional, Chantepie, Sylvain, additional, Pautas, Cécile, additional, Dombret, Hervé, additional, Preudhomme, Claude, additional, and Itzykson, Raphael, additional

Published
2022
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7. LSC17 Score Is Complementary with Minimal Residual Disease to Stratify NPM1-Mutated Acute Myeloid Leukemia: An ALFA Study

Author

Vasseur, Loïc, primary, Fenwarth, Laurène, additional, Thomas, Xavier, additional, Lambert, Jérôme, additional, de Botton, Stéphane, additional, Figeac, Martin, additional, Villenet, Céline, additional, Dumas, Pierre-Yves, additional, Recher, Christian, additional, Berthon, Céline, additional, Lemasle, Emilie, additional, Lebon, Delphine, additional, Lambert, Juliette, additional, Terré, Christine, additional, Celli-Lebras, Karine, additional, Dombret, Hervé, additional, Preudhomme, Claude, additional, Cheok, Meyling, additional, Itzykson, Raphael, additional, and Duployez, Nicolas, additional

Published
2022
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8. UBTFtandem duplications define a distinct subtype of adult de novo acute myeloid leukemia

Author

Duployez, Nicolas, Vasseur, Loïc, Kim, Rathana, Largeaud, Laëtitia, Passet, Marie, L’Haridon, Anaïs, Lemaire, Pierre, Fenwarth, Laurène, Geffroy, Sandrine, Helevaut, Nathalie, Celli‑Lebras, Karine, Adès, Lionel, Lebon, Delphine, Berthon, Céline, Marceau-Renaut, Alice, Cheok, Meyling, Lambert, Juliette, Récher, Christian, Raffoux, Emmanuel, Micol, Jean-Baptiste, Pigneux, Arnaud, Gardin, Claude, Delabesse, Eric, Soulier, Jean, Hunault, Mathilde, Dombret, Hervé, Itzykson, Raphael, Clappier, Emmanuelle, and Preudhomme, Claude

Abstract

Tandem duplications (TDs) of the UBTFgene have been recently described as a recurrent alteration in pediatric acute myeloid leukemia (AML). Here, by screening 1946 newly diagnosed adult AML, we found that UBTF-TDs occur in about 3% of patients aged 18–60 years, in a mutually exclusive pattern with other known AML subtype-defining alterations. The characteristics of 59 adults with UBTF-TD AML included young age (median 37 years), low bone marrow (BM) blast infiltration (median 25%), and high rates of WT1mutations (61%), FLT3-ITDs (51%) and trisomy 8 (29%). BM morphology frequently demonstrates dysmyelopoiesis albeit modulated by the co-occurrence of FLT3-ITD. UBTF-TD patients have lower complete remission (CR) rates (57% after 1 course and 76% after 2 courses of intensive chemotherapy [ICT]) than UBTF-wild-type patients. In patients enrolled in the ALFA-0702 study (n= 614 patients including 21 with UBTF-TD AML), the 3-year disease-free survival (DFS) and overall survival of UBTF-TD patients were 42.9% (95%CI: 23.4–78.5%) and 57.1% (95%CI: 39.5–82.8%) and did not significantly differ from those of ELN 2022 intermediate/adverse risk patients. Finally, the study of paired diagnosis and relapsed/refractory AML samples suggests that WT1-mutated clones are frequently selected under ICT. This study supports the recognition of UBTF-TD AML as a new AML entity in adults.

Published
2023
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9. HLA-Matched Related Hematopoietic Stem Cell Transplantation in Adolescents and Adults with Sickle Cell Disease: Comparison of Myeloablative Versus Non Myeloablative Approaches. Report from the Société Francophone De Greffe De Moelle Et De Thérapie Cellulaire

Author

Dhedin, Nathalie, primary, Chevillon, Florian, additional, Castelle, Martin, additional, Lavoipierre, Virginie, additional, Dalle, Jean-Hugues, additional, Vasseur, Loïc, additional, Joseph, Laure, additional, Beckerich, Florence, additional, Buchbinder, Nimrod, additional, Coman, Tereza, additional, Garban, Frederic, additional, Ferster, Alina, additional, Boissel, Nicolas, additional, Nguyen Quoc, Stephanie, additional, Arlet, Jean-Benoit, additional, and Pondarré, Corinne, additional

Published
2021
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10. Early Immune Reconstitution after Hematopoietic Stem Cell Transplantation for Adolescents and Adults with Sickle Cell Disease

Author

Vasseur, Loïc, primary, Morin, Florence, additional, Pondarré, Corinne, additional, Chevillon, Florian, additional, Fourmont, Aude-Marie, additional, Peffault De Latour, Regis, additional, Boissel, Nicolas, additional, Moins-Teisserenc, Hélène, additional, Caillat-Zucman, Sophie, additional, and Dhedin, Nathalie, additional

Published
2021
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13. Niche-like Ex Vivo High Throughput (NEXT) Drug Screening Platform in Acute Myeloid Leukemia

Author

Figueiras, Reinaldo Dal Bello, Pasanisi, Justine, Joudinaud, Romane, Duchmann, Matthieu, Sodaro, Gaetano, Chauvel, Clementine, Vasseur, Loic, Pardieu, Bryann, Ling, Frank, Pacchiardi, Kim, Vaganay, Camille, Faivre, Lionel, Benaksas, Chaïma, Preudhomme, Claude, Raffoux, Emmanuel, Clappier, Emmanuelle, Ades, Lionel, Puissant, Alexandre, and Itzykson, Raphael

Published
2020
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14. Hyperleukocytosis Increases the Risk of Early Relapses Independently of Genetics in AML

Author

Liévin, Raphaël, Duployez, Nicolas, Vasseur, Loïc, Lambert, Juliette, Heiblig, Mael, Hunault, Mathilde, Gardin, Claude, De Botton, Stephane, Fournier, Elise, Pautas, Cecile, Terré, Christine, Delabesse, Eric, Ifrah, Norbert, Pigneux, Arnaud, Karine, Celli-Lebras, Recher, Christian, Preudhomme, Claude, Dombret, Herve, and Itzykson, Raphael

Abstract

Background. Higher white blood cell (WBC) count at diagnosis is associated with specific gene lesions and higher early death rates in AML patients (pts) treated intensively. Whether higher WBC count at diagnosis affects outcome beyond remission independently of genetics is unknown.

Published
2023
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15. NGS-Based Stratification Refines the Risk Stratification in T-ALL and Identifies a Very High-Risk Subgroup of Patients

Author

Simonin, Mathieu, Vasseur, Loïc, Lengline, Etienne, Lhermitte, Ludovic, Cabannes-Hamy, Aurelie, Balsat, Marie, Schmidt, Aline, Dourthe, Marie Emilie, Touzart, Aurore, Graux, Carlos, Grardel, Nathalie, Cayuela, Jean-Michel, Arnoux, Isabelle, Gandemer, Virginie, Huguet, Françoise, Ducassou, Stephane, Lhéritier, Véronique, Chalandon, Yves, Ifrah, Norbert, Dombret, Herve, Macintyre, Elizabeth A., Petit, Arnaud, Rousselot, Philippe, Lambert, Jerome, Baruchel, André, Boissel, Nicolas, and Asnafi, Vahid

Abstract

Purpose

Published
2023
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16. Genomic Characterization of Acute Myeloid Leukemia with Aberrations of Chromosome 7: A Multinational Cohort of 523 Patients

Author

Halik, Adriane, Tilgner, Marlon, Silva, Patricia, Estrada-Barreras, Natalia, Altwasser, Robert, Jahn, Ekaterina, Heuser, Michael, Hou, Hsin-An, Pratcorona, Marta, Hills, Robert Kerrin, Metzeler, Klaus H, Fenwarth, Laurène, Dolnik, Anna, Terré, Christine, Kopp, Klara, Szyska, Martin, Krönke, Jan, Vasseur, Loïc, Lowenberg, Bob, Esteve, Jordi, Valk, Peter J. M., Duchmann, Matthieu, Chou, Wen-Chien, Linch, David C., Döhner, Hartmut, Gale, Rosemary E., Döhner, Konstanze, Bullinger, Lars, Yoshida, Kenichi, and Damm, Frederik

Abstract

Introduction: Aberrations of chromosome 7 [abn(7)] are found in ≈ 10% of newly diagnosed acute myeloid leukemia (AML) and associate with a dismal prognosis. A large-scale comprehensive exploration of the underlying genetic heterogeneity in AML with abn(7) has yet to be performed and could add essential insights into the outcome of this poorly understood patient group.

Published
2023
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17. Intra-Tumor Heterogeneity (ITH) in Acute Myeloid Leukemia (AML)

Author

Cerrano, Marco, Passet, Marie, Vasseur, Loic, Rabian, Florence, Rhamé, Rhamy, Lengliné, Etienne, Raffoux, Emmanuel, Dhédin, Nathalie, Cabannes-Hamy, Aurélie, Rahal, Ilhem, Sébert, Marie, Cucuinni, Wendy, Maarek, Odile, Raimbault, Anna, Mathis, Stéphanie, Celli-Lebras, Karine, Adès, Lionel, Fenaux, Pierre, Boissel, Nicolas, Soulier, Jean, Dombret, Hervé, Sujobert, Pierre, Clappier, Emmanuelle, and Itzykson, Raphael

Published
2019
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18. Prognostic Impact of Monoallelic Versus Biallelic TP53Alterations in Intensively-Treated Adults AML Patients: A Retrospective Study from the ALFA Group

Author

Fenwarth, Laurène, Vasseur, Loïc, Duployez, Nicolas, Gardin, Claude, Terré, Christine, Lambert, Juliette, de Botton, Stéphane, Celli-Lebras, Karine, Turlure, Pascal, Cluzeau, Thomas, Braun, Thorsten, Thomas, Xavier, Recher, Christian, Chantepie, Sylvain, Pautas, Cécile, Dombret, Hervé, Preudhomme, Claude, and Itzykson, Raphael

Published
2022
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