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47 results on '"VAN DER VLIS M"'

1. Borderline repeat expansion in Huntington's disease

Author: de Koning Gans, P.A.M., Losekoot, M., Bakker, E., den Dunnen, J.T., Vegter-van der Vlis, M., Roos, R.A.C., and van Ommen, G.J.B.
Published: 1993

2. Medical Advice for Sick-reported Students (MASS) in intermediate vocational education schools: Design of a controlled before-and-after study

Author: Van Der Vlis, M. (Madelon), Lugtenberg, M. (Marjolein), Vanneste, Y.T.M. (Yvonne T.M.), Berends, W. (Wenda), Mulder, W. (Wico), Bannink, R. (Rienke), Grieken, A. (Amy) van, Raat, H. (Hein), Kroon, M.L.A. (Marlou) de, Van Der Vlis, M. (Madelon), Lugtenberg, M. (Marjolein), Vanneste, Y.T.M. (Yvonne T.M.), Berends, W. (Wenda), Mulder, W. (Wico), Bannink, R. (Rienke), Grieken, A. (Amy) van, Raat, H. (Hein), and Kroon, M.L.A. (Marlou) de
Abstract: Background: School absenteeism, including medical absenteeism, is associated with early school dropout and may result in physical, mental, social and work-related problems in later life. Especially at intermediate vocational education schools, high rates of medical absenteeism are found. In 2012 the Dutch intervention 'Medical Advice for Sick-reported Students' (MASS), previously developed for pre-vocational secondary education, was adjusted for intermediate vocational education schools. The aim of the study outlined in this paper is to evaluate the effectiveness of the MASS intervention at intermediate vocational education schools in terms of reducing students' medical absenteeism and early dropping out of school. Additionally, the extent to which biopsychosocial and other factors moderate the effectiveness of the intervention will be assessed. Methods: A controlled before-and-after study will be conducted within Intermediate Vocational Education schools. Schools are allocated to be an intervention or control school based on whether the schools have implemented the MASS intervention (intervention schools) or not (control schools). Intervention schools apply the MASS intervention consisting of active support for students with medical absenteeism provided by the school including a consultation with the Youth Health Care (YHC) professional if needed. Control schools provide care as usual. Data will be collected by questionnaires among students in both groups meeting the criteria for extensive medical absenteeism (i.e. 'reported sick four times in 12 school weeks or for more than six consecutive school days' at baseline and at 6 months follow-up). Additionally, in the intervention group a questionnaire is completed after each consultation with a YHC professional, by both the student and the YHC professional. Primary outcome measures are duration and cumulative incidence of absenteeism and academic performances. Secondary outcome measures are biopsychosocial outcomes of
Published: 2017
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3. Amyloid B protein precursor gene and hereditary cerebral hemorrhage with amyloidosis (Dutch)

Author: Van Broeckhoven, C., Haan, J., Bakker, E., Hardy, J.A., Van Hul, W., Wehnert, A., Vegter-Van der Vlis, M., and Roos, R.A.C.
Subjects: Amyloidosis -- Physiological aspects, Science and technology, Physiological aspects
Abstract: Amyloid β Protein Precursor Gene and Hereditary Cerebral Hemorrhage with Amyloidosis (Dutch) DEPOSITION OF AMYLOID β PROtein fibrils in the walls of the small vasculature of the leptomeninges and the [...]
Published: 1990

4. Planck pre-launch status: The Planck mission

Author: Tauber, J, Mandolesi, N, Puget, J, Banos, T, Bersanelli, M, Bouchet, F, Butler, R, Charra, J, Crone, G, Dodsworth, J, Efstathiou, G, Gispert, R, Guyot, G, Gregorio, A, Juillet, J, Lamarre, J, Laureijs, R, Lawrence, C, NØRGAARD NIELSEN, H, Passvogel, T, Reix, J, Texier, D, Vibert, L, Zacchei, A, Ade, P, Aghanim, N, Aja, B, Alippi, E, Aloy, L, Armand, P, Arnaud, M, Arondel, A, ARREOLA VILLANUEVA, A, Artal, E, Artina, E, Arts, A, Ashdown, M, Aumont, J, Azzaro, M, Bacchetta, A, Baccigalupi, C, Baker, M, Balasini, M, Balbi, A, Banday, A, Barbier, G, Barreiro, R, Bartelmann, M, Battaglia, P, Battaner, E, Benabed, K, Beney, J, Beneyton, R, Bennett, K, Benoit, A, Bernard, J, Bhandari, P, Bhatia, R, Biggi, M, Biggins, R, Billig, G, Blanc, Y, Blavot, H, Bock, J, Bonaldi, A, Bond, R, Bonis, J, Borders, J, Borrill, J, Boschini, L, Boulanger, F, Bouvier, J, Bouzit, M, Bowman, R, Bréelle, E, Bradshaw, T, Braghin, M, Bremer, M, Brienza, D, Broszkiewicz, D, Burigana, C, Burkhalter, M, Cabella, P, Cafferty, T, Cairola, M, Caminade, S, Camus, P, Cantalupo, C, Cappellini, B, Cardoso, J, Carr, R, Catalano, A, Cayón, L, Cesa, M, Chaigneau, M, Challinor, A, Chamballu, A, Chambelland, J, Charra, M, Chiang, L, Chlewicki, G, Christensen, P, Church, S, Ciancietta, E, Cibrario, M, Cizeron, R, Clements, D, Collaudin, B, Colley, J, Colombi, S, Colombo, A, Colombo, F, Corre, O, Couchot, F, Cougrand, B, Coulais, A, Couzin, P, Crane, B, Crill, B, Crook, M, Crumb, D, Cuttaia, F, Dörl, U, DA SILVA, P, Daddato, R, Damasio, C, Danese, L, D'Aquino, G, D'Arcangelo, O, Dassas, K, Davies, R, Davies, W, Davis, R, DE BERNARDIS, P, DE CHAMBURE, D, DE GASPERIS, G, DE LA FUENTE, M, DE PACO, P, DE ROSA, A, DE TROIA, G, DE ZOTTI, G, Dehamme, M, Delabrouille, J, Delouis, J, Désert, F, DI GIROLAMO, G, Dickinson, C, Doelling, E, Dolag, K, Domken, I, Douspis, M, Doyle, D, Du, S, Dubruel, D, Dufour, C, Dumesnil, C, Dupac, X, Duret, P, Eder, C, Elfving, A, Enlin, T, Eng, P, English, K, Eriksen, H, Estaria, P, Falvella, M, Ferrari, F, Finelli, F, Fishman, A, Fogliani, S, Foley, S, Fonseca, A, Forma, G, Forni, O, Fosalba, P, Fourmond, J, Frailis, M, Franceschet, C, Franceschi, E, François, S, Frerking, M, GÓMEZ REÑASCO, M, Górski, K, Gaier, T, Galeotta, S, Ganga, K, GARCÍA LÁZARO, J, Garnica, A, Gaspard, M, Gavila, E, Giard, M, Giardino, G, Gienger, G, GIRAUD HERAUD, Y, Glorian, J, Griffin, M, Gruppuso, A, Guglielmi, L, Guichon, D, Guillaume, B, Guillouet, P, Haissinski, J, Hansen, F, Hardy, J, Harrison, D, Hazell, A, Hechler, M, Heckenauer, V, Heinzer, D, Hell, R, HENROT VERSILLÉ, S, HERNÁNDEZ MONTEAGUDO, C, Herranz, D, Herreros, J, Hervier, V, Heske, A, Heurtel, A, Hildebrandt, S, Hills, R, Hivon, E, Hobson, M, Hollert, D, Holmes, W, Hornstrup, A, Hovest, W, Hoyland, R, Huey, G, Huffenberger, K, Hughes, N, Israelsson, U, Jackson, B, Jaffe, A, Jaffe, T, Jagemann, T, Jessen, N, Jewell, J, Jones, W, Juvela, M, Kaplan, J, Karlman, P, Keck, F, Keihänen, E, King, M, Kisner, T, Kletzkine, P, Kneissl, R, Knoche, J, Knox, L, Koch, T, Krassenburg, M, KURKI SUONIO, H, Lähteenmäki, A, Lagache, G, Lagorio, E, Lami, P, Lande, J, Lange, A, Langlet, F, Lapini, R, Lapolla, M, Lasenby, A, LE JEUNE, M, Leahy, J, Lefebvre, M, Legrand, F, LE MEUR, G, Leonardi, R, Leriche, B, Leroy, C, Leutenegger, P, Levin, S, Lilje, P, Lindensmith, C, LINDEN VØRNLE, M, Loc, A, Longval, Y, Lubin, P, Luchik, T, Luthold, I, MACIAS PEREZ, J, Maciaszek, T, Mactavish, C, Madden, S, Maffei, B, Magneville, C, Maino, D, Mambretti, A, Mansoux, B, Marchioro, D, Maris, M, Marliani, F, Marrucho, J, MARTÍ CANALES, J, MARTÍNEZ GONZÁLEZ, E, MARTÍN POLEGRE, A, Martin, P, Marty, C, Marty, W, Masi, S, Massardi, M, Matarrese, S, Matthai, F, Mazzotta, P, Mcdonald, A, Mcgrath, P, Mediavilla, A, Meinhold, P, Mélin, J, Melot, F, Mendes, L, Mennella, A, Mervier, C, Meslier, L, Miccolis, M, MIVILLE DESCHENES, M, Moneti, A, Montet, D, Montier, L, Mora, J, Morgante, G, Morigi, G, Morinaud, G, Morisset, N, Mortlock, D, Mottet, S, Mulder, J, Munshi, D, Murphy, A, Murphy, P, Musi, P, Narbonne, J, Naselsky, P, Nash, A, Nati, F, Natoli, P, Netterfield, B, Newell, J, Nexon, M, Nicolas, C, Nielsen, P, Ninane, N, Noviello, F, Novikov, D, Novikov, I, O'Dwyer, I, Oldeman, P, Olivier, P, Ouchet, L, Oxborrow, C, PÉREZ CUEVAS, L, Pagan, L, Paine, C, Pajot, F, Paladini, R, Pancher, F, Panh, J, Parks, G, Parnaudeau, P, Partridge, B, Parvin, B, Pascual, J, Pasian, F, Pearson, D, Pearson, T, Pecora, M, Perdereau, O, Perotto, L, Perrotta, F, Piacentini, F, Piat, M, Pierpaoli, E, Piersanti, O, Plaige, E, Plaszczynski, S, Platania, P, Pointecouteau, E, Polenta, G, Ponthieu, N, Popa, L, Poulleau, G, Poutanen, T, Prézeau, G, Pradell, L, Prina, M, Prunet, S, Rachen, J, Rambaud, D, Rame, F, Rasmussen, I, Rautakoski, J, Reach, W, Rebolo, R, Reinecke, M, Reiter, J, Renault, C, Ricciardi, S, Rideau, P, Riller, T, Ristorcelli, I, Riti, J, Rocha, G, Roche, Y, Pons, R, Rohlfs, R, Romero, D, Roose, S, Rosset, C, Rouberol, S, ROWAN ROBINSON, M, RUBIÑO MARTÍN, J, Rusconi, P, Rusholme, B, Salama, M, Salerno, E, Sandri, M, Santos, D, Sanz, J, Sauter, L, Sauvage, F, Savini, G, Schmelzel, M, Schnorhk, A, Schwarz, W, Scott, D, Seiffert, M, Shellard, P, Shih, C, Sias, M, Silk, J, Silvestri, R, Sippel, R, Smoot, G, Starck, J, Stassi, P, Sternberg, J, Stivoli, F, Stolyarov, V, Stompor, R, Stringhetti, L, Strommen, D, Stute, T, Sudiwala, R, Sugimura, R, Sunyaev, R, Sygnet, J, Türler, M, Taddei, E, Tallon, J, Tamiatto, C, Taurigna, M, Taylor, D, Terenzi, L, Thuerey, S, Tillis, J, Tofani, G, Toffolatti, L, Tommasi, E, Tomasi, M, Tonazzini, E, Torre, J, Tosti, S, Touze, F, Tristram, M, Tuovinen, J, Tuttlebee, M, Umana, G, Valenziano, L, Vallée, D, VAN DER VLIS, M, VAN LEEUWEN, F, Vanel, J, VAN TENT, B, Varis, J, Vassallo, E, Vescovi, C, Vezzu, F, Vibert, D, Vielva, P, Vierra, J, Villa, F, Vittorio, N, Vuerli, C, Wade, L, Walker, A, Wandelt, B, Watson, C, Werner, D, White, M, White, S, Wilkinson, A, Wilson, P, Woodcraft, A, Yoffo, B, Yun, M, Yurchenko, V, Yvon, D, Zhang, B, Zimmermann, O, Zonca, A, Zorita, D, TAUBER J. A, MANDOLESI N, PUGET J. L, BANOS T, BERSANELLI M, BOUCHET F. R, BUTLER R. C, CHARRA J, CRONE G, DODSWORTH J, EFSTATHIOU G, GISPERT R, GUYOT G, GREGORIO A, JUILLET J. J, LAMARRE J. M, LAUREIJS R. J, LAWRENCE C. R, NØRGAARD NIELSEN H. U, PASSVOGEL T, REIX J. M, TEXIER D, VIBERT L, ZACCHEI A, ADE P. A. R, AGHANIM N, AJA B, ALIPPI E, ALOY L, ARMAND P, ARNAUD M, ARONDEL A, ARREOLA VILLANUEVA A, ARTAL E, ARTINA E, ARTS A, ASHDOWN M, AUMONT J, AZZARO M, BACCHETTA A, BACCIGALUPI C, BAKER M, BALASINI M, BALBI A, BANDAY A. J, BARBIER G, BARREIRO R. B, BARTELMANN M, BATTAGLIA P, BATTANER E, BENABED K, BENEY J. L, BENEYTON R, BENNETT K, BENOIT A, BERNARD J. P, BHANDARI P, BHATIA R, BIGGI M, BIGGINS R, BILLIG G, BLANC Y, BLAVOT H, BOCK J. J, BONALDI A, BOND R, BONIS J, BORDERS J, BORRILL J, BOSCHINI L, BOULANGER F, BOUVIER J, BOUZIT M, BOWMAN R, BRÉELLE E, BRADSHAW T, BRAGHIN M, BREMER M, BRIENZA, DANIELE, BROSZKIEWICZ D, BURIGANA C, BURKHALTER M, CABELLA, PAOLO, CAFFERTY T, CAIROLA M, CAMINADE S, CAMUS P, CANTALUPO C. M, CAPPELLINI B, CARDOSO J. F, CARR R, CATALANO, Andrea, CAYÓN L, CESA M, CHAIGNEAU M, CHALLINOR A, CHAMBALLU A, CHAMBELLAND J. P, CHARRA M, CHIANG L. Y, CHLEWICKI G, CHRISTENSEN P. R, CHURCH S, CIANCIETTA E, CIBRARIO M, CIZERON R, CLEMENTS D, COLLAUDIN B, COLLEY J. M, COLOMBI S, COLOMBO A, COLOMBO F, CORRE O, COUCHOT F, COUGRAND B, COULAIS A, COUZIN P, CRANE B, CRILL B, CROOK M, CRUMB D, CUTTAIA F, DÖRL U, DA SILVA P, DADDATO R, DAMASIO C, DANESE L, D'AQUINO G, D'ARCANGELO O, DASSAS K, DAVIES R. D, DAVIES W, DAVIS R. J, DE BERNARDIS, Paolo, DE CHAMBURE D, DE GASPERIS G, DE LA FUENTE M. L, DE PACO P, DE ROSA A, DE TROIA, Grazia, DE ZOTTI G, DEHAMME M, DELABROUILLE J, DELOUIS J. M, DÉSERT F. X, DI GIROLAMO G, DICKINSON C, DOELLING E, DOLAG K, DOMKEN I, DOUSPIS M, DOYLE D, DU S, DUBRUEL D, DUFOUR C, DUMESNIL C, DUPAC X, DURET P, EDER C, ELFVING A, ENLIN T. A, ENG P, ENGLISH K, ERIKSEN H. K, ESTARIA P, FALVELLA M. C, FERRARI F, FINELLI F, FISHMAN A, FOGLIANI S, FOLEY S, FONSECA A, FORMA G, FORNI O, FOSALBA P, FOURMOND J. J, FRAILIS M, FRANCESCHET C, FRANCESCHI E, FRANÇOIS S, FRERKING M, GÓMEZ REÑASCO M. F, GÓRSKI K. M, GAIER T. C, GALEOTTA S, GANGA K, GARCÍA LÁZARO J, GARNICA A, GASPARD M, GAVILA E, GIARD M, GIARDINO G, GIENGER G, GIRAUD HERAUD Y, GLORIAN J. M, GRIFFIN M, GRUPPUSO A, GUGLIELMI L, GUICHON D, GUILLAUME B, GUILLOUET P, HAISSINSKI J, HANSEN F. K, HARDY J, HARRISON D, HAZELL A, HECHLER M, HECKENAUER V, HEINZER D, HELL R, HENROT VERSILLÉ S, HERNÁNDEZ MONTEAGUDO C, HERRANZ D, HERREROS J. M, HERVIER V, HESKE A, HEURTEL A, HILDEBRANDT S. R, HILLS R, HIVON E, HOBSON M, HOLLERT D, HOLMES W, HORNSTRUP A, HOVEST W, HOYLAND R. J, HUEY G, HUFFENBERGER K. M, HUGHES N, ISRAELSSON U, JACKSON B, JAFFE A, JAFFE T. R, JAGEMANN T, JESSEN N. C, JEWELL J, JONES W, JUVELA M, KAPLAN J, KARLMAN P, KECK F, KEIHÄNEN E, KING M, KISNER T. S, KLETZKINE P, KNEISSL R, KNOCHE J, KNOX L, KOCH T, KRASSENBURG M, KURKI SUONIO H, LÄHTEENMÄKI A, LAGACHE G, LAGORIO E, LAMI P, LANDE J, LANGE A, LANGLET F, LAPINI R, LAPOLLA M, LASENBY A, LE JEUNE M, LEAHY J. P, LEFEBVRE M, LEGRAND F, LE MEUR G, LEONARDI R, LERICHE B, LEROY C, LEUTENEGGER P, LEVIN S. M, LILJE P. B, LINDENSMITH C, LINDEN VØRNLE M, LOC A, LONGVAL Y, LUBIN P. M, LUCHIK T, LUTHOLD I, MACIAS PEREZ J. F, MACIASZEK T, MACTAVISH C, MADDEN S, MAFFEI B, MAGNEVILLE C, MAINO D, MAMBRETTI A, MANSOUX B, MARCHIORO D, MARIS M, MARLIANI F, MARRUCHO J. C, MARTÍ CANALES J, MARTÍNEZ GONZÁLEZ E, MARTÍN POLEGRE A, MARTIN P, MARTY C, MARTY W, MASI, Silvia, MASSARDI M, MATARRESE S, MATTHAI F, MAZZOTTA P, MCDONALD A, MCGRATH P, MEDIAVILLA A, MEINHOLD P. R, MÉLIN J. B, MELOT F, MENDES L, MENNELLA A, MERVIER C, MESLIER L, MICCOLIS M, MIVILLE DESCHENES M. A, MONETI A, MONTET D, MONTIER L, MORA J, MORGANTE G, MORIGI G, MORINAUD G, MORISSET N, MORTLOCK D, MOTTET S, MULDER J, MUNSHI D, MURPHY A, MURPHY P, MUSI P, NARBONNE J, NASELSKY P, NASH A, NATI, FEDERICO, NATOLI P, NETTERFIELD B, NEWELL J, NEXON M, NICOLAS C, NIELSEN P. H, NINANE N, NOVIELLO F, NOVIKOV D, NOVIKOV I, O'DWYER I. J, OLDEMAN P, OLIVIER P, OUCHET L, OXBORROW C. A, PÉREZ CUEVAS L, PAGAN L, PAINE C, PAJOT F, PALADINI R, PANCHER F, PANH J, PARKS G, PARNAUDEAU P, PARTRIDGE B, PARVIN B, PASCUAL J. P, PASIAN F, PEARSON D. P, PEARSON T, PECORA M, PERDEREAU O, PEROTTO L, PERROTTA F, PIACENTINI, Francesco, PIAT M, PIERPAOLI E, PIERSANTI O, PLAIGE E, PLASZCZYNSKI S, PLATANIA P, POINTECOUTEAU E, POLENTA, GIANLUCA, PONTHIEU N, POPA L, POULLEAU G, POUTANEN T, PRÉZEAU G, PRADELL L, PRINA M, PRUNET S, RACHEN J. P, RAMBAUD D, RAME F, RASMUSSEN I, RAUTAKOSKI J, REACH W. T, REBOLO R, REINECKE M, REITER J, RENAULT C, RICCIARDI, Sara, RIDEAU P, RILLER T, RISTORCELLI I, RITI J. B, ROCHA G, ROCHE Y, PONS R, ROHLFS R, ROMERO D, ROOSE S, ROSSET C, ROUBEROL S, ROWAN ROBINSON M, RUBIÑO MARTÍN J. A, RUSCONI P, RUSHOLME B, SALAMA M, SALERNO E, SANDRI M, SANTOS D, SANZ J. L, SAUTER L, SAUVAGE F, SAVINI, Giorgio, SCHMELZEL M, SCHNORHK A, SCHWARZ W, SCOTT D, SEIFFERT M. D, SHELLARD P, SHIH C, SIAS M, SILK J. I, SILVESTRI R, SIPPEL R, SMOOT G. F, STARCK J. L, STASSI P, STERNBERG J, STIVOLI, federico, STOLYAROV V, STOMPOR R, STRINGHETTI L, STROMMEN D, STUTE T, SUDIWALA R, SUGIMURA R, SUNYAEV R, SYGNET J. F, TÜRLER M, TADDEI E, TALLON J, TAMIATTO C, TAURIGNA M, TAYLOR D, TERENZI L, THUEREY S, TILLIS J, TOFANI G, TOFFOLATTI L, TOMMASI E, TOMASI M, TONAZZINI E, TORRE J. P, TOSTI S, TOUZE F, TRISTRAM M, TUOVINEN J, TUTTLEBEE M, UMANA G, VALENZIANO L, VALLÉE D, VAN DER VLIS M, VAN LEEUWEN F, VANEL J. C, VAN TENT B, VARIS J, VASSALLO E, VESCOVI C, VEZZU F, VIBERT D, VIELVA P, VIERRA J, VILLA F, VITTORIO N, VUERLI C, WADE L. A, WALKER A. R, WANDELT B. D, WATSON C, WERNER D, WHITE M, WHITE S. D. M, WILKINSON A, WILSON P, WOODCRAFT A, YOFFO B, YUN M, YURCHENKO V, YVON D, ZHANG B, ZIMMERMANN O, ZONCA A, ZORITA D., Tauber, J, Mandolesi, N, Puget, J, Banos, T, Bersanelli, M, Bouchet, F, Butler, R, Charra, J, Crone, G, Dodsworth, J, Efstathiou, G, Gispert, R, Guyot, G, Gregorio, A, Juillet, J, Lamarre, J, Laureijs, R, Lawrence, C, NØRGAARD NIELSEN, H, Passvogel, T, Reix, J, Texier, D, Vibert, L, Zacchei, A, Ade, P, Aghanim, N, Aja, B, Alippi, E, Aloy, L, Armand, P, Arnaud, M, Arondel, A, ARREOLA VILLANUEVA, A, Artal, E, Artina, E, Arts, A, Ashdown, M, Aumont, J, Azzaro, M, Bacchetta, A, Baccigalupi, C, Baker, M, Balasini, M, Balbi, A, Banday, A, Barbier, G, Barreiro, R, Bartelmann, M, Battaglia, P, Battaner, E, Benabed, K, Beney, J, Beneyton, R, Bennett, K, Benoit, A, Bernard, J, Bhandari, P, Bhatia, R, Biggi, M, Biggins, R, Billig, G, Blanc, Y, Blavot, H, Bock, J, Bonaldi, A, Bond, R, Bonis, J, Borders, J, Borrill, J, Boschini, L, Boulanger, F, Bouvier, J, Bouzit, M, Bowman, R, Bréelle, E, Bradshaw, T, Braghin, M, Bremer, M, Brienza, D, Broszkiewicz, D, Burigana, C, Burkhalter, M, Cabella, P, Cafferty, T, Cairola, M, Caminade, S, Camus, P, Cantalupo, C, Cappellini, B, Cardoso, J, Carr, R, Catalano, A, Cayón, L, Cesa, M, Chaigneau, M, Challinor, A, Chamballu, A, Chambelland, J, Charra, M, Chiang, L, Chlewicki, G, Christensen, P, Church, S, Ciancietta, E, Cibrario, M, Cizeron, R, Clements, D, Collaudin, B, Colley, J, Colombi, S, Colombo, A, Colombo, F, Corre, O, Couchot, F, Cougrand, B, Coulais, A, Couzin, P, Crane, B, Crill, B, Crook, M, Crumb, D, Cuttaia, F, Dörl, U, DA SILVA, P, Daddato, R, Damasio, C, Danese, L, D'Aquino, G, D'Arcangelo, O, Dassas, K, Davies, R, Davies, W, Davis, R, DE BERNARDIS, P, DE CHAMBURE, D, DE GASPERIS, G, DE LA FUENTE, M, DE PACO, P, DE ROSA, A, DE TROIA, G, DE ZOTTI, G, Dehamme, M, Delabrouille, J, Delouis, J, Désert, F, DI GIROLAMO, G, Dickinson, C, Doelling, E, Dolag, K, Domken, I, Douspis, M, Doyle, D, Du, S, Dubruel, D, Dufour, C, Dumesnil, C, Dupac, X, Duret, P, Eder, C, Elfving, A, Enlin, T, Eng, P, English, K, Eriksen, H, Estaria, P, Falvella, M, Ferrari, F, Finelli, F, Fishman, A, Fogliani, S, Foley, S, Fonseca, A, Forma, G, Forni, O, Fosalba, P, Fourmond, J, Frailis, M, Franceschet, C, Franceschi, E, François, S, Frerking, M, GÓMEZ REÑASCO, M, Górski, K, Gaier, T, Galeotta, S, Ganga, K, GARCÍA LÁZARO, J, Garnica, A, Gaspard, M, Gavila, E, Giard, M, Giardino, G, Gienger, G, GIRAUD HERAUD, Y, Glorian, J, Griffin, M, Gruppuso, A, Guglielmi, L, Guichon, D, Guillaume, B, Guillouet, P, Haissinski, J, Hansen, F, Hardy, J, Harrison, D, Hazell, A, Hechler, M, Heckenauer, V, Heinzer, D, Hell, R, HENROT VERSILLÉ, S, HERNÁNDEZ MONTEAGUDO, C, Herranz, D, Herreros, J, Hervier, V, Heske, A, Heurtel, A, Hildebrandt, S, Hills, R, Hivon, E, Hobson, M, Hollert, D, Holmes, W, Hornstrup, A, Hovest, W, Hoyland, R, Huey, G, Huffenberger, K, Hughes, N, Israelsson, U, Jackson, B, Jaffe, A, Jaffe, T, Jagemann, T, Jessen, N, Jewell, J, Jones, W, Juvela, M, Kaplan, J, Karlman, P, Keck, F, Keihänen, E, King, M, Kisner, T, Kletzkine, P, Kneissl, R, Knoche, J, Knox, L, Koch, T, Krassenburg, M, KURKI SUONIO, H, Lähteenmäki, A, Lagache, G, Lagorio, E, Lami, P, Lande, J, Lange, A, Langlet, F, Lapini, R, Lapolla, M, Lasenby, A, LE JEUNE, M, Leahy, J, Lefebvre, M, Legrand, F, LE MEUR, G, Leonardi, R, Leriche, B, Leroy, C, Leutenegger, P, Levin, S, Lilje, P, Lindensmith, C, LINDEN VØRNLE, M, Loc, A, Longval, Y, Lubin, P, Luchik, T, Luthold, I, MACIAS PEREZ, J, Maciaszek, T, Mactavish, C, Madden, S, Maffei, B, Magneville, C, Maino, D, Mambretti, A, Mansoux, B, Marchioro, D, Maris, M, Marliani, F, Marrucho, J, MARTÍ CANALES, J, MARTÍNEZ GONZÁLEZ, E, MARTÍN POLEGRE, A, Martin, P, Marty, C, Marty, W, Masi, S, Massardi, M, Matarrese, S, Matthai, F, Mazzotta, P, Mcdonald, A, Mcgrath, P, Mediavilla, A, Meinhold, P, Mélin, J, Melot, F, Mendes, L, Mennella, A, Mervier, C, Meslier, L, Miccolis, M, MIVILLE DESCHENES, M, Moneti, A, Montet, D, Montier, L, Mora, J, Morgante, G, Morigi, G, Morinaud, G, Morisset, N, Mortlock, D, Mottet, S, Mulder, J, Munshi, D, Murphy, A, Murphy, P, Musi, P, Narbonne, J, Naselsky, P, Nash, A, Nati, F, Natoli, P, Netterfield, B, Newell, J, Nexon, M, Nicolas, C, Nielsen, P, Ninane, N, Noviello, F, Novikov, D, Novikov, I, O'Dwyer, I, Oldeman, P, Olivier, P, Ouchet, L, Oxborrow, C, PÉREZ CUEVAS, L, Pagan, L, Paine, C, Pajot, F, Paladini, R, Pancher, F, Panh, J, Parks, G, Parnaudeau, P, Partridge, B, Parvin, B, Pascual, J, Pasian, F, Pearson, D, Pearson, T, Pecora, M, Perdereau, O, Perotto, L, Perrotta, F, Piacentini, F, Piat, M, Pierpaoli, E, Piersanti, O, Plaige, E, Plaszczynski, S, Platania, P, Pointecouteau, E, Polenta, G, Ponthieu, N, Popa, L, Poulleau, G, Poutanen, T, Prézeau, G, Pradell, L, Prina, M, Prunet, S, Rachen, J, Rambaud, D, Rame, F, Rasmussen, I, Rautakoski, J, Reach, W, Rebolo, R, Reinecke, M, Reiter, J, Renault, C, Ricciardi, S, Rideau, P, Riller, T, Ristorcelli, I, Riti, J, Rocha, G, Roche, Y, Pons, R, Rohlfs, R, Romero, D, Roose, S, Rosset, C, Rouberol, S, ROWAN ROBINSON, M, RUBIÑO MARTÍN, J, Rusconi, P, Rusholme, B, Salama, M, Salerno, E, Sandri, M, Santos, D, Sanz, J, Sauter, L, Sauvage, F, Savini, G, Schmelzel, M, Schnorhk, A, Schwarz, W, Scott, D, Seiffert, M, Shellard, P, Shih, C, Sias, M, Silk, J, Silvestri, R, Sippel, R, Smoot, G, Starck, J, Stassi, P, Sternberg, J, Stivoli, F, Stolyarov, V, Stompor, R, Stringhetti, L, Strommen, D, Stute, T, Sudiwala, R, Sugimura, R, Sunyaev, R, Sygnet, J, Türler, M, Taddei, E, Tallon, J, Tamiatto, C, Taurigna, M, Taylor, D, Terenzi, L, Thuerey, S, Tillis, J, Tofani, G, Toffolatti, L, Tommasi, E, Tomasi, M, Tonazzini, E, Torre, J, Tosti, S, Touze, F, Tristram, M, Tuovinen, J, Tuttlebee, M, Umana, G, Valenziano, L, Vallée, D, VAN DER VLIS, M, VAN LEEUWEN, F, Vanel, J, VAN TENT, B, Varis, J, Vassallo, E, Vescovi, C, Vezzu, F, Vibert, D, Vielva, P, Vierra, J, Villa, F, Vittorio, N, Vuerli, C, Wade, L, Walker, A, Wandelt, B, Watson, C, Werner, D, White, M, White, S, Wilkinson, A, Wilson, P, Woodcraft, A, Yoffo, B, Yun, M, Yurchenko, V, Yvon, D, Zhang, B, Zimmermann, O, Zonca, A, Zorita, D, TAUBER J. A, MANDOLESI N, PUGET J. L, BANOS T, BERSANELLI M, BOUCHET F. R, BUTLER R. C, CHARRA J, CRONE G, DODSWORTH J, EFSTATHIOU G, GISPERT R, GUYOT G, GREGORIO A, JUILLET J. J, LAMARRE J. M, LAUREIJS R. J, LAWRENCE C. R, NØRGAARD NIELSEN H. U, PASSVOGEL T, REIX J. M, TEXIER D, VIBERT L, ZACCHEI A, ADE P. A. R, AGHANIM N, AJA B, ALIPPI E, ALOY L, ARMAND P, ARNAUD M, ARONDEL A, ARREOLA VILLANUEVA A, ARTAL E, ARTINA E, ARTS A, ASHDOWN M, AUMONT J, AZZARO M, BACCHETTA A, BACCIGALUPI C, BAKER M, BALASINI M, BALBI A, BANDAY A. J, BARBIER G, BARREIRO R. B, BARTELMANN M, BATTAGLIA P, BATTANER E, BENABED K, BENEY J. L, BENEYTON R, BENNETT K, BENOIT A, BERNARD J. P, BHANDARI P, BHATIA R, BIGGI M, BIGGINS R, BILLIG G, BLANC Y, BLAVOT H, BOCK J. J, BONALDI A, BOND R, BONIS J, BORDERS J, BORRILL J, BOSCHINI L, BOULANGER F, BOUVIER J, BOUZIT M, BOWMAN R, BRÉELLE E, BRADSHAW T, BRAGHIN M, BREMER M, BRIENZA, DANIELE, BROSZKIEWICZ D, BURIGANA C, BURKHALTER M, CABELLA, PAOLO, CAFFERTY T, CAIROLA M, CAMINADE S, CAMUS P, CANTALUPO C. M, CAPPELLINI B, CARDOSO J. F, CARR R, CATALANO, Andrea, CAYÓN L, CESA M, CHAIGNEAU M, CHALLINOR A, CHAMBALLU A, CHAMBELLAND J. P, CHARRA M, CHIANG L. Y, CHLEWICKI G, CHRISTENSEN P. R, CHURCH S, CIANCIETTA E, CIBRARIO M, CIZERON R, CLEMENTS D, COLLAUDIN B, COLLEY J. M, COLOMBI S, COLOMBO A, COLOMBO F, CORRE O, COUCHOT F, COUGRAND B, COULAIS A, COUZIN P, CRANE B, CRILL B, CROOK M, CRUMB D, CUTTAIA F, DÖRL U, DA SILVA P, DADDATO R, DAMASIO C, DANESE L, D'AQUINO G, D'ARCANGELO O, DASSAS K, DAVIES R. D, DAVIES W, DAVIS R. J, DE BERNARDIS, Paolo, DE CHAMBURE D, DE GASPERIS G, DE LA FUENTE M. L, DE PACO P, DE ROSA A, DE TROIA, Grazia, DE ZOTTI G, DEHAMME M, DELABROUILLE J, DELOUIS J. M, DÉSERT F. X, DI GIROLAMO G, DICKINSON C, DOELLING E, DOLAG K, DOMKEN I, DOUSPIS M, DOYLE D, DU S, DUBRUEL D, DUFOUR C, DUMESNIL C, DUPAC X, DURET P, EDER C, ELFVING A, ENLIN T. A, ENG P, ENGLISH K, ERIKSEN H. K, ESTARIA P, FALVELLA M. C, FERRARI F, FINELLI F, FISHMAN A, FOGLIANI S, FOLEY S, FONSECA A, FORMA G, FORNI O, FOSALBA P, FOURMOND J. J, FRAILIS M, FRANCESCHET C, FRANCESCHI E, FRANÇOIS S, FRERKING M, GÓMEZ REÑASCO M. F, GÓRSKI K. M, GAIER T. C, GALEOTTA S, GANGA K, GARCÍA LÁZARO J, GARNICA A, GASPARD M, GAVILA E, GIARD M, GIARDINO G, GIENGER G, GIRAUD HERAUD Y, GLORIAN J. M, GRIFFIN M, GRUPPUSO A, GUGLIELMI L, GUICHON D, GUILLAUME B, GUILLOUET P, HAISSINSKI J, HANSEN F. K, HARDY J, HARRISON D, HAZELL A, HECHLER M, HECKENAUER V, HEINZER D, HELL R, HENROT VERSILLÉ S, HERNÁNDEZ MONTEAGUDO C, HERRANZ D, HERREROS J. M, HERVIER V, HESKE A, HEURTEL A, HILDEBRANDT S. R, HILLS R, HIVON E, HOBSON M, HOLLERT D, HOLMES W, HORNSTRUP A, HOVEST W, HOYLAND R. J, HUEY G, HUFFENBERGER K. M, HUGHES N, ISRAELSSON U, JACKSON B, JAFFE A, JAFFE T. R, JAGEMANN T, JESSEN N. C, JEWELL J, JONES W, JUVELA M, KAPLAN J, KARLMAN P, KECK F, KEIHÄNEN E, KING M, KISNER T. S, KLETZKINE P, KNEISSL R, KNOCHE J, KNOX L, KOCH T, KRASSENBURG M, KURKI SUONIO H, LÄHTEENMÄKI A, LAGACHE G, LAGORIO E, LAMI P, LANDE J, LANGE A, LANGLET F, LAPINI R, LAPOLLA M, LASENBY A, LE JEUNE M, LEAHY J. P, LEFEBVRE M, LEGRAND F, LE MEUR G, LEONARDI R, LERICHE B, LEROY C, LEUTENEGGER P, LEVIN S. M, LILJE P. B, LINDENSMITH C, LINDEN VØRNLE M, LOC A, LONGVAL Y, LUBIN P. M, LUCHIK T, LUTHOLD I, MACIAS PEREZ J. F, MACIASZEK T, MACTAVISH C, MADDEN S, MAFFEI B, MAGNEVILLE C, MAINO D, MAMBRETTI A, MANSOUX B, MARCHIORO D, MARIS M, MARLIANI F, MARRUCHO J. C, MARTÍ CANALES J, MARTÍNEZ GONZÁLEZ E, MARTÍN POLEGRE A, MARTIN P, MARTY C, MARTY W, MASI, Silvia, MASSARDI M, MATARRESE S, MATTHAI F, MAZZOTTA P, MCDONALD A, MCGRATH P, MEDIAVILLA A, MEINHOLD P. R, MÉLIN J. B, MELOT F, MENDES L, MENNELLA A, MERVIER C, MESLIER L, MICCOLIS M, MIVILLE DESCHENES M. A, MONETI A, MONTET D, MONTIER L, MORA J, MORGANTE G, MORIGI G, MORINAUD G, MORISSET N, MORTLOCK D, MOTTET S, MULDER J, MUNSHI D, MURPHY A, MURPHY P, MUSI P, NARBONNE J, NASELSKY P, NASH A, NATI, FEDERICO, NATOLI P, NETTERFIELD B, NEWELL J, NEXON M, NICOLAS C, NIELSEN P. H, NINANE N, NOVIELLO F, NOVIKOV D, NOVIKOV I, O'DWYER I. J, OLDEMAN P, OLIVIER P, OUCHET L, OXBORROW C. A, PÉREZ CUEVAS L, PAGAN L, PAINE C, PAJOT F, PALADINI R, PANCHER F, PANH J, PARKS G, PARNAUDEAU P, PARTRIDGE B, PARVIN B, PASCUAL J. P, PASIAN F, PEARSON D. P, PEARSON T, PECORA M, PERDEREAU O, PEROTTO L, PERROTTA F, PIACENTINI, Francesco, PIAT M, PIERPAOLI E, PIERSANTI O, PLAIGE E, PLASZCZYNSKI S, PLATANIA P, POINTECOUTEAU E, POLENTA, GIANLUCA, PONTHIEU N, POPA L, POULLEAU G, POUTANEN T, PRÉZEAU G, PRADELL L, PRINA M, PRUNET S, RACHEN J. P, RAMBAUD D, RAME F, RASMUSSEN I, RAUTAKOSKI J, REACH W. T, REBOLO R, REINECKE M, REITER J, RENAULT C, RICCIARDI, Sara, RIDEAU P, RILLER T, RISTORCELLI I, RITI J. B, ROCHA G, ROCHE Y, PONS R, ROHLFS R, ROMERO D, ROOSE S, ROSSET C, ROUBEROL S, ROWAN ROBINSON M, RUBIÑO MARTÍN J. A, RUSCONI P, RUSHOLME B, SALAMA M, SALERNO E, SANDRI M, SANTOS D, SANZ J. L, SAUTER L, SAUVAGE F, SAVINI, Giorgio, SCHMELZEL M, SCHNORHK A, SCHWARZ W, SCOTT D, SEIFFERT M. D, SHELLARD P, SHIH C, SIAS M, SILK J. I, SILVESTRI R, SIPPEL R, SMOOT G. F, STARCK J. L, STASSI P, STERNBERG J, STIVOLI, federico, STOLYAROV V, STOMPOR R, STRINGHETTI L, STROMMEN D, STUTE T, SUDIWALA R, SUGIMURA R, SUNYAEV R, SYGNET J. F, TÜRLER M, TADDEI E, TALLON J, TAMIATTO C, TAURIGNA M, TAYLOR D, TERENZI L, THUEREY S, TILLIS J, TOFANI G, TOFFOLATTI L, TOMMASI E, TOMASI M, TONAZZINI E, TORRE J. P, TOSTI S, TOUZE F, TRISTRAM M, TUOVINEN J, TUTTLEBEE M, UMANA G, VALENZIANO L, VALLÉE D, VAN DER VLIS M, VAN LEEUWEN F, VANEL J. C, VAN TENT B, VARIS J, VASSALLO E, VESCOVI C, VEZZU F, VIBERT D, VIELVA P, VIERRA J, VILLA F, VITTORIO N, VUERLI C, WADE L. A, WALKER A. R, WANDELT B. D, WATSON C, WERNER D, WHITE M, WHITE S. D. M, WILKINSON A, WILSON P, WOODCRAFT A, YOFFO B, YUN M, YURCHENKO V, YVON D, ZHANG B, ZIMMERMANN O, ZONCA A, and ZORITA D.
Abstract: The European Space Agency's Planck satellite, launched on 14 May 2009, is the third-generation space experiment in the field of cosmic microwave background (CMB) research. It will image the anisotropies of the CMB over the whole sky, with unprecedented sensitivity (${{\Delta T}\over T}$ ~ 2 × 10-6) and angular resolution (~5 arcmin). Planck will provide a major source of information relevant to many fundamental cosmological problems and will test current theories of the early evolution of the Universe and the origin of structure. It will also address a wide range of areas of astrophysical research related to the Milky Way as well as external galaxies and clusters of galaxies. The ability of Planck to measure polarization across a wide frequency range (30-350 GHz), with high precision and accuracy, and over the whole sky, will provide unique insight, not only into specific cosmological questions, but also into the properties of the interstellar medium. This paper is part of a series which describes the technical capabilities of the Planck scientific payload. It is based on the knowledge gathered during the on-ground calibration campaigns of the major subsystems, principally its telescope and its two scientific instruments, and of tests at fully integrated satellite level. It represents the best estimate before launch of the technical performance that the satellite and its payload will achieve in flight. In this paper, we summarise the main elements of the payload performance, which is described in detail in the accompanying papers. In addition, we describe the satellite performance elements which are most relevant for science, and provide an overview of the plans for scientific operations and data analysis.
Published: 2010

5. Toekomstverkenning en organisatieontwikkeling. Ontwerpkeuzes in het scenarioproject RWS 2020

Author: van Twist, Marcus, van der Steen, MA, van der Vlis, M, Demkes, R, Public Administration, and Department of Technology and Operations Management
Published: 2009

6. The Presymptomatic Diagnosis of Huntington’s Disease Using Molecular Techniques, Applications and New Developments

Author: Skraastad, M. I., primary, Verwest, A., additional, Bakkers, E., additional, de Rooij, K., additional, Vegter-van der Vlis, M., additional, Roos, R. A. C., additional, van Ommen, G. J. B., additional, and Pearson, P. L., additional
Published: 1989
Full Text: View/download PDF

7. Huntington’s Chorea

Author: Went, L. N., primary, Vegter-Van Der Vlis, M., additional, Volkers, W., additional, and Collewijn, H., additional
Published: 1975
Full Text: View/download PDF

8. Distress in individuals facing predictive DNA testing for autosomal dominant late-onset disorders: comparing questionnaire results with in-depth interviews

Author: Dudok-de Wit, A. C., Tibben, A., Duivenvoorden, H. J., Niermeijer, M. F., Passchier, J., Trijsburg, R. W., Lindhout, D., Meijers-Heijboer, E. J., Frets, P. G., Lodder, L. N., Zoetewij, M. W., Klijn, J. G. M., Brocker-Vriends, A., van Haeringen, A., Helderman, A. T. J. M., Hilhorst-Hofstee, Y., Kant, S., Maat-Kievit, J. A., Oosterwijk, J. C., van der Smagt, J. J., Vegter-van der Vlis, M., Vries-van der Weerd, M. A. C. S., Zoeteweij, M. W., Bakker, E., Devilee, P., Losekoot, M., Tops, C., Cornelisse, C. J., Vasen, H. F. A., Psychiatry, Clinical Genetics, and Other departments
Subjects: Coping (psychology), medicine.diagnostic_test, media_common.quotation_subject, Genetic counseling, Hospital Anxiety and Depression Scale, Distress, Denial, Beck Hopelessness Scale, medicine, Anxiety, medicine.symptom, Psychology, Genetics (clinical), Clinical psychology, media_common, Genetic testing
Abstract: In 50% risk carriers for Huntington disease (n = 41), hereditary cerebral hemorrhage with amyloidosis Dutch-type (n = 9) familial adenomatous polyposis coli (n = 45) and hereditary breast and ovarian cancer (n = 24), pretest intrusion and avoidance (Impact of Event Scale), anxiety and depression (Hospital Anxiety and Depression Scale), feelings of hopelessness (Beck Hopelessness Scale), and psychological complaints (Symptom Checklist) were assessed to determine their psychological well-being, The manner of discussing the genetic disorder, the test, and its implications during a semistructured interview (reflecting on one's emotions without getting carried away or dismissing or minimizing the subject) was judged in terms of coherence, Participants at risk for neurodegenerative disorders had higher anxiety and depression scores and more psychological complaints than did those at risk for cancer syndromes, Those reporting high intrusion/high avoidance had higher anxiety and depression scores and more psychological complaints than did those reporting low intrusion/low avoidance, However, the scoring of the interview showed that participants reporting high intrusion/high avoidance were more reflective about their emotions without getting carried away or dismissing the subject (e.g., more coherent) than those reporting low intrusion/low avoidance, This result suggests that participants with higher stress scores may be actively dealing with the emotional implications of the test, whereas those with low stress scores may (as yet) be unable to face these implications, It is important to identify the strategy of coping with threat to provide suitable counseling and necessary guidance, However, long-term follow-up is needed to learn the consequences of a denial coping strategy for those participating in a genetic testing program, (C) 1998 Wiley-Liss, Inc
Published: 1998

9. De glasvezel: het publiek belang van een technologische transitie

Author: den Butter, F.A.G., van der Vlis, M., den Butter, F.A.G., and van der Vlis, M.
Published: 2005

10. Planckpre-launch status: ThePlanckmission

Author: Tauber, J. A., primary, Mandolesi, N., additional, Puget, J.-L., additional, Banos, T., additional, Bersanelli, M., additional, Bouchet, F. R., additional, Butler, R. C., additional, Charra, J., additional, Crone, G., additional, Dodsworth, J., additional, Efstathiou, G., additional, Gispert, R., additional, Guyot, G., additional, Gregorio, A., additional, Juillet, J. J., additional, Lamarre, J.-M., additional, Laureijs, R. J., additional, Lawrence, C. R., additional, Nørgaard-Nielsen, H. U., additional, Passvogel, T., additional, Reix, J. M., additional, Texier, D., additional, Vibert, L., additional, Zacchei, A., additional, Ade, P. A. R., additional, Aghanim, N., additional, Aja, B., additional, Alippi, E., additional, Aloy, L., additional, Armand, P., additional, Arnaud, M., additional, Arondel, A., additional, Arreola-Villanueva, A., additional, Artal, E., additional, Artina, E., additional, Arts, A., additional, Ashdown, M., additional, Aumont, J., additional, Azzaro, M., additional, Bacchetta, A., additional, Baccigalupi, C., additional, Baker, M., additional, Balasini, M., additional, Balbi, A., additional, Banday, A. J., additional, Barbier, G., additional, Barreiro, R. B., additional, Bartelmann, M., additional, Battaglia, P., additional, Battaner, E., additional, Benabed, K., additional, Beney, J.-L., additional, Beneyton, R., additional, Bennett, K., additional, Benoit, A., additional, Bernard, J.-P., additional, Bhandari, P., additional, Bhatia, R., additional, Biggi, M., additional, Biggins, R., additional, Billig, G., additional, Blanc, Y., additional, Blavot, H., additional, Bock, J. J., additional, Bonaldi, A., additional, Bond, R., additional, Bonis, J., additional, Borders, J., additional, Borrill, J., additional, Boschini, L., additional, Boulanger, F., additional, Bouvier, J., additional, Bouzit, M., additional, Bowman, R., additional, Bréelle, E., additional, Bradshaw, T., additional, Braghin, M., additional, Bremer, M., additional, Brienza, D., additional, Broszkiewicz, D., additional, Burigana, C., additional, Burkhalter, M., additional, Cabella, P., additional, Cafferty, T., additional, Cairola, M., additional, Caminade, S., additional, Camus, P., additional, Cantalupo, C. M., additional, Cappellini, B., additional, Cardoso, J.-F., additional, Carr, R., additional, Catalano, A., additional, Cayón, L., additional, Cesa, M., additional, Chaigneau, M., additional, Challinor, A., additional, Chamballu, A., additional, Chambelland, J. P., additional, Charra, M., additional, Chiang, L.-Y., additional, Chlewicki, G., additional, Christensen, P. R., additional, Church, S., additional, Ciancietta, E., additional, Cibrario, M., additional, Cizeron, R., additional, Clements, D., additional, Collaudin, B., additional, Colley, J.-M., additional, Colombi, S., additional, Colombo, A., additional, Colombo, F., additional, Corre, O., additional, Couchot, F., additional, Cougrand, B., additional, Coulais, A., additional, Couzin, P., additional, Crane, B., additional, Crill, B., additional, Crook, M., additional, Crumb, D., additional, Cuttaia, F., additional, Dörl, U., additional, da Silva, P., additional, Daddato, R., additional, Damasio, C., additional, Danese, L., additional, d'Aquino, G., additional, D'Arcangelo, O., additional, Dassas, K., additional, Davies, R. D., additional, Davies, W., additional, Davis, R. J., additional, De Bernardis, P., additional, de Chambure, D., additional, de Gasperis, G., additional, De la Fuente, M. L., additional, De Paco, P., additional, De Rosa, A., additional, De Troia, G., additional, De Zotti, G., additional, Dehamme, M., additional, Delabrouille, J., additional, Delouis, J.-M., additional, Désert, F.-X., additional, di Girolamo, G., additional, Dickinson, C., additional, Doelling, E., additional, Dolag, K., additional, Domken, I., additional, Douspis, M., additional, Doyle, D., additional, Du, S., additional, Dubruel, D., additional, Dufour, C., additional, Dumesnil, C., additional, Dupac, X., additional, Duret, P., additional, Eder, C., additional, Elfving, A., additional, Enßlin, T. A., additional, Eng, P., additional, English, K., additional, Eriksen, H. K., additional, Estaria, P., additional, Falvella, M. C., additional, Ferrari, F., additional, Finelli, F., additional, Fishman, A., additional, Fogliani, S., additional, Foley, S., additional, Fonseca, A., additional, Forma, G., additional, Forni, O., additional, Fosalba, P., additional, Fourmond, J.-J., additional, Frailis, M., additional, Franceschet, C., additional, Franceschi, E., additional, François, S., additional, Frerking, M., additional, Gómez-Reñasco, M. F., additional, Górski, K. M., additional, Gaier, T. C., additional, Galeotta, S., additional, Ganga, K., additional, García Lázaro, J., additional, Garnica, A., additional, Gaspard, M., additional, Gavila, E., additional, Giard, M., additional, Giardino, G., additional, Gienger, G., additional, Giraud-Heraud, Y., additional, Glorian, J.-M., additional, Griffin, M., additional, Gruppuso, A., additional, Guglielmi, L., additional, Guichon, D., additional, Guillaume, B., additional, Guillouet, P., additional, Haissinski, J., additional, Hansen, F. K., additional, Hardy, J., additional, Harrison, D., additional, Hazell, A., additional, Hechler, M., additional, Heckenauer, V., additional, Heinzer, D., additional, Hell, R., additional, Henrot-Versillé, S., additional, Hernández-Monteagudo, C., additional, Herranz, D., additional, Herreros, J. M., additional, Hervier, V., additional, Heske, A., additional, Heurtel, A., additional, Hildebrandt, S. R., additional, Hills, R., additional, Hivon, E., additional, Hobson, M., additional, Hollert, D., additional, Holmes, W., additional, Hornstrup, A., additional, Hovest, W., additional, Hoyland, R. J., additional, Huey, G., additional, Huffenberger, K. M., additional, Hughes, N., additional, Israelsson, U., additional, Jackson, B., additional, Jaffe, A., additional, Jaffe, T. R., additional, Jagemann, T., additional, Jessen, N. C., additional, Jewell, J., additional, Jones, W., additional, Juvela, M., additional, Kaplan, J., additional, Karlman, P., additional, Keck, F., additional, Keihänen, E., additional, King, M., additional, Kisner, T. S., additional, Kletzkine, P., additional, Kneissl, R., additional, Knoche, J., additional, Knox, L., additional, Koch, T., additional, Krassenburg, M., additional, Kurki-Suonio, H., additional, Lähteenmäki, A., additional, Lagache, G., additional, Lagorio, E., additional, Lami, P., additional, Lande, J., additional, Lange, A., additional, Langlet, F., additional, Lapini, R., additional, Lapolla, M., additional, Lasenby, A., additional, Le Jeune, M., additional, Leahy, J. P., additional, Lefebvre, M., additional, Legrand, F., additional, Le Meur, G., additional, Leonardi, R., additional, Leriche, B., additional, Leroy, C., additional, Leutenegger, P., additional, Levin, S. M., additional, Lilje, P. B., additional, Lindensmith, C., additional, Linden-Vørnle, M., additional, Loc, A., additional, Longval, Y., additional, Lubin, P. M., additional, Luchik, T., additional, Luthold, I., additional, Macias-Perez, J. F., additional, Maciaszek, T., additional, MacTavish, C., additional, Madden, S., additional, Maffei, B., additional, Magneville, C., additional, Maino, D., additional, Mambretti, A., additional, Mansoux, B., additional, Marchioro, D., additional, Maris, M., additional, Marliani, F., additional, Marrucho, J.-C., additional, Martí-Canales, J., additional, Martínez-González, E., additional, Martín-Polegre, A., additional, Martin, P., additional, Marty, C., additional, Marty, W., additional, Masi, S., additional, Massardi, M., additional, Matarrese, S., additional, Matthai, F., additional, Mazzotta, P., additional, McDonald, A., additional, McGrath, P., additional, Mediavilla, A., additional, Meinhold, P. R., additional, Mélin, J.-B., additional, Melot, F., additional, Mendes, L., additional, Mennella, A., additional, Mervier, C., additional, Meslier, L., additional, Miccolis, M., additional, Miville-Deschenes, M.-A., additional, Moneti, A., additional, Montet, D., additional, Montier, L., additional, Mora, J., additional, Morgante, G., additional, Morigi, G., additional, Morinaud, G., additional, Morisset, N., additional, Mortlock, D., additional, Mottet, S., additional, Mulder, J., additional, Munshi, D., additional, Murphy, A., additional, Murphy, P., additional, Musi, P., additional, Narbonne, J., additional, Naselsky, P., additional, Nash, A., additional, Nati, F., additional, Natoli, P., additional, Netterfield, B., additional, Newell, J., additional, Nexon, M., additional, Nicolas, C., additional, Nielsen, P. H., additional, Ninane, N., additional, Noviello, F., additional, Novikov, D., additional, Novikov, I., additional, O'Dwyer, I. J., additional, Oldeman, P., additional, Olivier, P., additional, Ouchet, L., additional, Oxborrow, C. A., additional, Pérez-Cuevas, L., additional, Pagan, L., additional, Paine, C., additional, Pajot, F., additional, Paladini, R., additional, Pancher, F., additional, Panh, J., additional, Parks, G., additional, Parnaudeau, P., additional, Partridge, B., additional, Parvin, B., additional, Pascual, J. P., additional, Pasian, F., additional, Pearson, D. P., additional, Pearson, T., additional, Pecora, M., additional, Perdereau, O., additional, Perotto, L., additional, Perrotta, F., additional, Piacentini, F., additional, Piat, M., additional, Pierpaoli, E., additional, Piersanti, O., additional, Plaige, E., additional, Plaszczynski, S., additional, Platania, P., additional, Pointecouteau, E., additional, Polenta, G., additional, Ponthieu, N., additional, Popa, L., additional, Poulleau, G., additional, Poutanen, T., additional, Prézeau, G., additional, Pradell, L., additional, Prina, M., additional, Prunet, S., additional, Rachen, J. P., additional, Rambaud, D., additional, Rame, F., additional, Rasmussen, I., additional, Rautakoski, J., additional, Reach, W. T., additional, Rebolo, R., additional, Reinecke, M., additional, Reiter, J., additional, Renault, C., additional, Ricciardi, S., additional, Rideau, P., additional, Riller, T., additional, Ristorcelli, I., additional, Riti, J. B., additional, Rocha, G., additional, Roche, Y., additional, Pons, R., additional, Rohlfs, R., additional, Romero, D., additional, Roose, S., additional, Rosset, C., additional, Rouberol, S., additional, Rowan-Robinson, M., additional, Rubiño-Martín, J. A., additional, Rusconi, P., additional, Rusholme, B., additional, Salama, M., additional, Salerno, E., additional, Sandri, M., additional, Santos, D., additional, Sanz, J. L., additional, Sauter, L., additional, Sauvage, F., additional, Savini, G., additional, Schmelzel, M., additional, Schnorhk, A., additional, Schwarz, W., additional, Scott, D., additional, Seiffert, M. D., additional, Shellard, P., additional, Shih, C., additional, Sias, M., additional, Silk, J. I., additional, Silvestri, R., additional, Sippel, R., additional, Smoot, G. F., additional, Starck, J.-L., additional, Stassi, P., additional, Sternberg, J., additional, Stivoli, F., additional, Stolyarov, V., additional, Stompor, R., additional, Stringhetti, L., additional, Strommen, D., additional, Stute, T., additional, Sudiwala, R., additional, Sugimura, R., additional, Sunyaev, R., additional, Sygnet, J.-F., additional, Türler, M., additional, Taddei, E., additional, Tallon, J., additional, Tamiatto, C., additional, Taurigna, M., additional, Taylor, D., additional, Terenzi, L., additional, Thuerey, S., additional, Tillis, J., additional, Tofani, G., additional, Toffolatti, L., additional, Tommasi, E., additional, Tomasi, M., additional, Tonazzini, E., additional, Torre, J.-P., additional, Tosti, S., additional, Touze, F., additional, Tristram, M., additional, Tuovinen, J., additional, Tuttlebee, M., additional, Umana, G., additional, Valenziano, L., additional, Vallée, D., additional, van der Vlis, M., additional, Van Leeuwen, F., additional, Vanel, J.-C., additional, Van-Tent, B., additional, Varis, J., additional, Vassallo, E., additional, Vescovi, C., additional, Vezzu, F., additional, Vibert, D., additional, Vielva, P., additional, Vierra, J., additional, Villa, F., additional, Vittorio, N., additional, Vuerli, C., additional, Wade, L. A., additional, Walker, A. R., additional, Wandelt, B. D., additional, Watson, C., additional, Werner, D., additional, White, M., additional, White, S. D. M., additional, Wilkinson, A., additional, Wilson, P., additional, Woodcraft, A., additional, Yoffo, B., additional, Yun, M., additional, Yurchenko, V., additional, Yvon, D., additional, Zhang, B., additional, Zimmermann, O., additional, Zonca, A., additional, and Zorita, D., additional
Published: 2010
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11. [Presymptomatic DNA diagnosis in Huntington's chorea: reactions to the certainty of not being a genetic carrier]

Author: Aad Tibben, Vegter-van der Vlis M, Ra, Roos, Jj, Kamp, Pg, Frets, and Verhage F
Subjects: Adult, Huntington Disease, Genetic Techniques, Genetic Carrier Screening, Guilt, Humans, Sibling Relations, Female, DNA, Anger
Abstract: Presymptomatic DNA diagnostics in Huntington's chorea make it possible to establish with approx. 98% certainty whether an at-risk person is a gene carrier. Sympathy and care are usually shown to those demonstrated to have the gene and so will become affected in the future. Persons shown not to be carriers sometimes do not experience the expected relief. The authors successively discuss the effects of a favourable finding on the family system, such as survivor's guilt and emotional numbing as aspects of a coping process. It is concluded that even a favourable finding needs to be worked through, a process that takes years rather than months.
Published: 1990

12. Intelligence indices in people with a high/low risk for developing Huntington's disease.

Author: de Boo, G M, primary, Tibben, A, additional, Lanser, J B, additional, Jennekens-Schinkel, A, additional, Hermans, J, additional, Vegter-van der Vlis, M, additional, and Roos, R A, additional
Published: 1997
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13. Psychological effects of presymptomatic DNA testing for Huntingtonʼs disease in the Dutch program.

Author: Tibben, A, primary, Duivenvoorden, H J, additional, Niermeijer, M F, additional, Vegter-van der Vlis, M, additional, Roos, R A, additional, and Verhage, F, additional
Published: 1994
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14. Dynamic mutation in Dutch Huntington's disease patients: increased paternal repeat instability extending to within the normal size range.

Author: De Rooij, K E, primary, De Koning Gans, P A, additional, Skraastad, M I, additional, Belfroid, R D, additional, Vegter-Van Der Vlis, M, additional, Roos, R A, additional, Bakker, E, additional, Van Ommen, G J, additional, Den Dunnen, J T, additional, and Losekoot, M, additional
Published: 1993
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15. Duration of illness in Huntington's disease is not related to age at onset.

Author: Roos, R A, primary, Hermans, J, additional, Vegter-van der Vlis, M, additional, van Ommen, G J, additional, and Bruyn, G W, additional
Published: 1993
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16. Age at onset in Huntington's disease: effect of line of inheritance and patient's sex.

Author: Roos, R A, primary, Vegter-van der Vlis, M, additional, Hermans, J, additional, Elshove, H M, additional, Moll, A C, additional, van de Kamp, J J, additional, and Bruyn, G W, additional
Published: 1991
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17. Paradox of a better test for Huntington's disease.

Author: Maat-Kievit, A, Vegter-van der Vlis, M, Zoeteweij, M, Losekoot, M, van Haeringen, A, and Roos, R
Abstract: Objectives: To describe the consequences of the identification of the Huntington's disease (HD) mutation on predictive and prenatal testing.Methods: A retrospective study was performed considering the test applicants, procedures, and results before and after the identification of the mutation. 1032 people at risk for Huntington's disease in The Netherlands were included, of whom 741 applied for the predictive test in the period 1987 to 1997 in Leiden at the Department of Clinical Genetics, and after 1994, also in the other seven clinical genetics departments in The Netherlands. Uptake, sociodemographic variables, and test results, taken before and after the mutation was identified, are described.Results: The uptake of the predictive test in the period studied was 24% and for the prenatal test 2%. No differences were noted in numbers and sociodemographic data between the period before and after the mutation was identified. After an initial increase in test applicants, a decrease was seen after 1995. After 1993 a significant increase of 25% at risk test applicants and a significant decrease of prenatal exclusion tests was noticed. Only 7% asked for reassessment by mutation analysis. New problems arose after the identification of the mutation, such as the option of reassessing the risk obtained by linkage analysis, direct mutation testing of 25% at risk persons with a parent who does not wish to know, new choices regarding reproduction, and new uncertainties for carriers of intermediate and reduced penetrance alleles and for their offspring and relatives.Conclusions: Although predictive testing has become reliable and available for every person at risk since the mutation has been identified, the uptake of predictive and prenatal tests fell short of expectation, no change in sociodemographic variables was seen, and a decrease in number of applicants was noted. Furthermore, new uncertainties, psychological problems, and questions arose. [ABSTRACT FROM AUTHOR]
Published: 2000

18. Epidemiological and clinical aspects of hereditary cerebral hemorrhage in Dutch families

Author: Vegter-van der Vlis M, Bots Gt, Went Ln, and Luyendijk W
Subjects: Adult, Pediatrics, medicine.medical_specialty, business.industry, Middle Aged, Epidemiology, Medicine, Humans, Surgery, Neurology (clinical), business, Epidemiologic Methods, Aged, Cerebral Hemorrhage, Netherlands
Published: 1987

19. [Procedure and initial results of presymptomatic DNA studies in Huntington's chorea]

Author: Ra, Roos, Vegter-van der Vlis M, Aad Tibben, Mi, Skraastad, and Pl, Pearson
Subjects: Adult, Genetic Markers, Male, Huntington Disease, Adolescent, Genetic Carrier Screening, Humans, Reproducibility of Results, Female, DNA, Middle Aged, Pedigree
Abstract: The availability of DNA-markers more tightly linked to the Huntington's disease locus made presymptomatic and exclusion testing possible with an accuracy of up to 98%. The testing programme started in Leiden in August 1987. In 56 adults with 25% and 50% risks presymptomatic tests were performed. In 8 persons the risk was increased to 98%, in 17 it was decreased to less than 5%. In two instances the test was not informative. The remaining 29 persons have not yet been tested for different reasons. So far 3 exclusion tests were requested: one showed a decreased risk, one has not yet been performed and one request was rejected. The results and the reactions to the test are discussed.

20. PARENTAL TRANSMISSION IN HUNTINGTON'S DISEASE

Author: Went, L.N., primary, Vegter-van der Vlis, M., additional, and Bruyn, G.W., additional
Published: 1984
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21. Hereditary cerebral haemorrhage caused by cortical amyloid angiopathy

Author: Luyendijk, W., primary, Bots, G.T.A.M., additional, Vegter-van der Vlis, M., additional, Went, L.N., additional, and Frangione, B., additional
Published: 1988
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22. HUNTINGTON'S CHOREA

Author: Baraitser, M., Betts, T., Bird, E.D., Bolt, J.M.W., Bruyn, G.W., Bundey, S., Caro, A.J., Corney, G., Corsellis, J.A.N., Edwards, J.H., Glendinning, N.W., Harper, P.S., Heathfield, K.W.G., Hetherington, R.J., Hughes, Brodie, Hughes, R.C., Insley, J., Jefferson, J.M., Marshall, W.H., Matthews, W.B., Pearce, G.W., Sims, A.C.P., Smith, W.Thomas, Spokes, E., Stevens, D.L., Vegter-van der Vlis, M., and Went, L.N.
Published: 1977
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23. Oculomotor defects in patients with Huntington's disease and their offspring

Author: Collewijn, H., Went, L.N., Tamminga, E.P., and Vegter-Van der Vlis, M.
Published: 1988
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24. Planck pre-launch status: The Planck mission

Author: J. A. Tauber1, N. Mandolesi2, J.-L. Puget3, T. Banos4, M. Bersanelli5, F. R. Bouchet6, R. C. Butler2, J. Charra3, G. Crone7, J. Dodsworth8, G. Efstathiou9, R. Gispert3, G. Guyot3, A. Gregorio10, J. J. Juillet4, J.-M. Lamarre11, R. J. Laureijs1, C. R. Lawrence12, H. U. Nørgaard-Nielsen13, T. Passvogel7, J. M. Reix4, D. Texier14, L. Vibert3, A. Zacchei15, P. A. R. Ade16, N. Aghanim3, B. Aja17, E. Alippi18, L. Aloy7, P. Armand4, M. Arnaud19, A. Arondel3, A. Arreola-Villanueva12, E. Artal17, E. Artina18, A. Arts7, M. Ashdown20, J. Aumont21, M. Azzaro22, A. Bacchetta23, C. Baccigalupi24, M. Baker7, M. Balasini18, A. Balbi25, A. J. Banday26, G. Barbier28, R. B. Barreiro29, M. Bartelmann26, P. Battaglia18, E. Battaner31, K. Benabed6, J.-L. Beney32, R. Beneyton6, K. Bennett1, A. Benoit28, J.-P. Bernard27, P. Bhandari12, R. Bhatia12, M. Biggi33, R. Biggins8, G. Billig8, Y. Blanc34, H. Blavot3, J. J. Bock12, A. Bonaldi35, R. Bond36, J. Bonis32, J. Borders12, J. Borrill37, L. Boschini18, F. Boulanger3, J. Bouvier28, M. Bouzit3, R. Bowman12, E. Bréelle38, T. Bradshaw39, M. Braghin7, M. Bremer1, D. Brienza40, D. Broszkiewicz38, C. Burigana2, M. Burkhalter41, P. Cabella25, T. Cafferty12, M. Cairola23, S. Caminade3, P. Camus42, C. M. Cantalupo43, B. Cappellini5, J.-F. Cardoso38, R. Carr14, A. Catalano38, L. Cayón44, M. Cesa23, M. Chaigneau3, A. Challinor9, A. Chamballu45, J. P. Chambelland4, M. Charra3, L.-Y. Chiang46, G. Chlewicki23, P. R. Christensen47, S. Church48, E. Ciancietta23, M. Cibrario23, R. Cizeron32, D. Clements45, B. Collaudin4, J.-M. Colley38, 6, S. Colombi6, A. Colombo7, F. Colombo18, O. Corre4, F. Couchot32, B. Cougrand3, A. Coulais11, P. Couzin4, B. Crane3, B. Crill12, M. Crook39, D. Crumb12, F. Cuttaia2, U. Dörl26, P. da Silva6, R. Daddato7, C. Damasio7, L. Danese24, G. d'Aquino7, O. D'Arcangelo49, K. Dassas3, R. D. Davies50, W. Davies41, R. J. Davis50, P. De Bernardis40, D. de Chambure7, G. de Gasperis25, M. L. De la Fuente17, P. De Paco51, A. De Rosa2, G. De Troia25, G. De Zotti35, M. Dehamme32, J. Delabrouille38, J.-M. Delouis6, F.-X. Désert28, G. di Girolamo8, C. Dickinson50, E. Doelling8, K. Dolag26, I. Domken52, M. Douspis3, D. Doyle7, S. Du32, D. Dubruel4, C. Dufour38, C. Dumesnil3, X. Dupac14, P. Duret3, C. Eder32, A. Elfving7, T. A. Enßlin26, P. Eng3, K. English12, H. K. Eriksen53, P. Estaria7, M. C. Falvella55, F. Ferrari18, F. Finelli2, A. Fishman12, S. Fogliani15, S. Foley8, A. Fonseca12, G. Forma4, O. Forni27, P. Fosalba56, J.-J. Fourmond3, M. Frailis15, C. Franceschet5, E. Franceschi2, S. François3, M. Frerking12, M. F. Gómez-Reñasco57, K. M. Górski12, T. C. Gaier12, S. Galeotta58, K. Ganga38, J. García Lázaro14, A. Garnica12, M. Gaspard32, E. Gavila4, M. Giard27, G. Giardino1, G. Gienger8, Y. Giraud-Heraud38, J.-M. Glorian27, M. Griffin16, A. Gruppuso2, L. Guglielmi38, D. Guichon4, B. Guillaume7, P. Guillouet38, J. Haissinski32, F. K. Hansen53, J. Hardy12, D. Harrison9, A. Hazell59, M. Hechler8, V. Heckenauer3, D. Heinzer8, R. Hell26, S. Henrot-Versillé32, C. Hernández-Monteagudo26, D. Herranz29, J. M. Herreros57, V. Hervier3, A. Heske7, A. Heurtel32, S. R. Hildebrandt57, R. Hills20, E. Hivon6, M. Hobson20, D. Hollert12, W. Holmes12, A. Hornstrup13, W. Hovest26, R. J. Hoyland57, G. Huey12, K. M. Huffenberger60, N. Hughes61, U. Israelsson12, B. Jackson7, A. Jaffe45, T. R. Jaffe50, T. Jagemann14, N. C. Jessen13, J. Jewell12, W. Jones62, M. Juvela63, J. Kaplan38, P. Karlman12, F. Keck8, E. Keihänen64, M. King12, T. S. Kisner43, P. Kletzkine7, R. Kneissl26, J. Knoche26, L. Knox65, T. Koch12, M. Krassenburg7, H. Kurki-Suonio64, A. Lähteenmäki67, G. Lagache3, E. Lagorio28, P. Lami3, J. Lande27, A. Lange12, F. Langlet3, R. Lapini33, M. Lapolla18, A. Lasenby20, M. Le Jeune38, J. P. Leahy50, M. Lefebvre3, F. Legrand6, G. Le Meur32, R. Leonardi68, B. Leriche3, C. Leroy3, P. Leutenegger18, S. M. Levin12, P. B. Lilje53, C. Lindensmith12, M. Linden-Vørnle69, A. Loc12, Y. Longval3, P. M. Lubin68, T. Luchik12, I. Luthold7, J. F. Macias-Perez70, T. Maciaszek34, C. MacTavish45, S. Madden7, B. Maffei50, C. Magneville71, D. Maino5, A. Mambretti18, B. Mansoux32, D. Marchioro18, M. Maris15, F. Marliani7, J.-C. Marrucho32, J. Martí-Canales7, E. Martínez-González29, A. Martín-Polegre7, P. Martin4, C. Marty27, W. Marty27, S. Masi40, M. Massardi35, S. Matarrese72, F. Matthai26, P. Mazzotta25, A. McDonald8, P. McGrath12, A. Mediavilla17, P. R. Meinhold68, J.-B. Mélin71, F. Melot70, L. Mendes14, A. Mennella5, C. Mervier3, L. Meslier3, M. Miccolis18, M.-A. Miville-Deschenes3, A. Moneti6, D. Montet4, L. Montier27, J. Mora12, G. Morgante2, G. Morigi2, G. Morinaud3, N. Morisset73, D. Mortlock9, S. Mottet6, J. Mulder12, D. Munshi9, A. Murphy74, P. Murphy12, P. Musi23, J. Narbonne27, P. Naselsky47, A. Nash12, F. Nati40, P. Natoli25, B. Netterfield36, J. Newell12, M. Nexon27, C. Nicolas3, P. H. Nielsen75, N. Ninane52, F. Noviello3, D. Novikov45, I. Novikov47, I. J. O'Dwyer12, P. Oldeman7, P. Olivier7, L. Ouchet4, C. A. Oxborrow13, L. Pérez-Cuevas7, L. Pagan18, C. Paine12, F. Pajot3, R. Paladini76, F. Pancher28, J. Panh34, G. Parks12, P. Parnaudeau6, B. Partridge77, B. Parvin12, J. P. Pascual17, F. Pasian15, D. P. Pearson12, T. Pearson12, M. Pecora18, O. Perdereau32, L. Perotto70, F. Perrotta24, F. Piacentini40, M. Piat38, E. Pierpaoli78, O. Piersanti7, E. Plaige32, S. Plaszczynski32, P. Platania49, E. Pointecouteau27, G. Polenta79, N. Ponthieu3, L. Popa80, G. Poulleau3, T. Poutanen64, G. Prézeau12, L. Pradell81, M. Prina12, S. Prunet6, J. P. Rachen26, D. Rambaud27, F. Rame23, I. Rasmussen7, J. Rautakoski7, W. T. Reach82, R. Rebolo57, M. Reinecke26, J. Reiter12, C. Renault70, S. Ricciardi83, P. Rideau4, T. Riller26, I. Ristorcelli27, J. B. Riti4, G. Rocha12, Y. Roche4, R. Pons27, R. Rohlfs73, D. Romero12, S. Roose52, C. Rosset32, S. Rouberol6, M. Rowan-Robinson45, J. A. Rubiño-Martín57, P. Rusconi18, B. Rusholme82, M. Salama12, E. Salerno84, M. Sandri2, D. Santos70, J. L. Sanz29, L. Sauter6, F. Sauvage4, G. Savini85, M. Schmelzel12, A. Schnorhk7, W. Schwarz12, D. Scott86, M. D. Seiffert12, P. Shellard20, C. Shih12, M. Sias23, J. I. Silk87, R. Silvestri18, R. Sippel88, G. F. Smoot89, J.-L. Starck71, P. Stassi70, J. Sternberg1, F. Stivoli83, V. Stolyarov9, R. Stompor38, L. Stringhetti2, D. Strommen12, T. Stute88, R. Sudiwala16, R. Sugimura12, R. Sunyaev26, J.-F. Sygnet6, M. Türler73, E. Taddei18, J. Tallon12, C. Tamiatto3, M. Taurigna32, D. Taylor14, L. Terenzi2, S. Thuerey7, J. Tillis12, G. Tofani90, L. Toffolatti91, E. Tommasi55, M. Tomasi5, E. Tonazzini84, J.-P. Torre3, S. Tosti3, F. Touze32, M. Tristram32, J. Tuovinen92, M. Tuttlebee8, G. Umana93, L. Valenziano2, D. Vallée38, M. van der Vlis7, F. Van Leeuwen9, J.-C. Vanel38, B. Van-Tent6, J. Varis92, E. Vassallo8, C. Vescovi28, F. Vezzu28, D. Vibert6, P. Vielva29, J. Vierra12, F. Villa2, N. Vittorio25, C. Vuerli15, L. A. Wade12, A. R. Walker86, B. D. Wandelt94, C. Watson8, D. Werner8, M. White95, S. D. M. White26, A. Wilkinson50, P. Wilson12, A. Woodcraft16, B. Yoffo38, M. Yun12, V. Yurchenko74, D. Yvon71, B. Zhang12, O. Zimmermann28, A. Zonca58, D. Zorita96, Universitat Politècnica de Catalunya. Departament de Teoria del Senyal i Comunicacions, Universitat Politècnica de Catalunya. RF&MW - Grup de Recerca de sistemes, dispositius i materials de RF i microones, TAUBER J., A, Mandolesi, N, PUGET J., L, Banos, T, Bersanelli, M, BOUCHET F., R, BUTLER C., R, Charra, J, Crone, G, Dodsworth, J, Efstathiou, G, Gispert, R, Guyot, G, Gregorio, Anna, JUILLET J., J, LAMARRE J., M, LAUREIJS R., J, LAWRENCE C., R, NØRGAARD NIELSEN H., U, Passvogel, T, REIX J., M, Texier, D, Vibert, L, Zacchei, A, ADE P. A., R, Aghanim, N, Aja, B, Alippi, E, Aloy, L, Armand, P, Arnaud, M, Arondel, A, ARREOLA VILLANUEVA, A, Artal, E, Artina, E, Arts, A, Ashdown, M, Aumont, J, Azzaro, M, Bacchetta, A, Baccigalupi, C, Baker, M, Balasini, M, Balbi, A, BANDAY A., J, Barbier, G, BARREIRO R., B, Bartelmann, M, Battaglia, P, Battaner, E, Benabed, K, BENEY J., L, Beneyton, R, Bennett, K, Benoit, A, BERNARD J., P, Bhandari, P, Bhatia, R, Biggi, M, Biggins, R, Billig, G, Blanc, Y, Blavot, H, BOCK J., J, Bonaldi, A, Bond, R, Bonis, J, Borders, J, Borrill, J, Boschini, L, Boulanger, F, Bouvier, J, Bouzit, M, Bowman, R, Brelle, E, Bradshaw, T, Braghin, M, Bremer, M, Brienza, D, Broszkiewicz, D, Burigana, C, Burkhalter, M, Cabella, P, Cafferty, T, Cairola, M, Caminade, S, Camus, P, CANTALUPO C., M, Cappellini, B, CARDOSO J., F, Carr, R, Catalano, A, Cayon, L, Cesa, M, Chaigneau, M, Challinor, A, Chamballu, A, CHAMBELLAND J., P, Charra, M, CHIANG L., Y, Chlewicki, G, CHRISTENSEN P., R, Church, S, Ciancietta, E, Cibrario, M, Cizeron, R, Clements, D, Collaudin, B, COLLEY J., M, Colombi, S, Colombo, A, Colombo, F, Corre, O, Couchot, F, Cougrand, B, Coulais, A, Couzin, P, Crane, B, Crill, B, Crook, M, Crumb, D, Cuttaia, F, Dorl, U, DA SILVA, P, Daddato, R, Damasio, C, Danese, L, Daquino, G, Darcangelo, O, Dassas, K, DAVIES R., D, Davies, W, DAVIS R., J, DE BERNARDIS, P, DE CHAMBURE, D, DE GASPERIS, G, DE LA FUENTA M., L, DE PACO, P, DE ROSA, A, DE TROIA, G, DE ZOTTI, G, Dehamme, M, Delabrouille, J, DELOUIS J., M, DESERT F., X, DI GIROLAMO, G, Dickinson, C, Doelling, E, Dolag, K, Domken, I, Douspis, M, Doyle, D, Du, S, Dubruel, D, Dufour, C, Dumesnil, C, Dupac, X, Duret, P, Eder, C, Elfving, A, ENLIN T., A, Eng, P, English, K, ERIKSEN H., K, Estaria, P, FALVELLA M., C, Ferrari, F, Finelli, F, Fishman, A, Fogliani, S, Foley, S, Fonseca, A, Forma, G, Forni, O, Fosalba, P, ., ., Universidad de Cantabria, Institut d'astrophysique spatiale (IAS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Institut d'Astrophysique de Paris (IAP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique (LERMA), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Astrophysique de Grenoble (LAOG), Université Joseph Fourier - Grenoble 1 (UJF)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), APC - Gravitation (APC-Gravitation), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Max-Planck-Institut für Gravitationsphysik ( Albert-Einstein-Institut ) (AEI), Max-Planck-Gesellschaft-Max-Planck-Gesellschaft, APC - Cosmologie, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), PLANCK, Tauber, J, Puget, J, Bouchet, F, Butler, R, Gregorio, A, Juillet, J, Lamarre, J, Laureijs, R, Lawrence, C, NØRGAARD NIELSEN, H, Reix, J, Ade, P, Banday, A, Barreiro, R, Beney, J, Bernard, J, Bock, J, Bréelle, E, Cantalupo, C, Cardoso, J, Cayón, L, Chambelland, J, Chiang, L, Christensen, P, Colley, J, Dörl, U, D'Aquino, G, D'Arcangelo, O, Davies, R, Davis, R, DE LA FUENTE, M, Delouis, J, Désert, F, Enlin, T, Eriksen, H, Falvella, M, Fourmond, J, Frailis, M, Franceschet, C, Franceschi, E, François, S, Frerking, M, GÓMEZ REÑASCO, M, Górski, K, Gaier, T, Galeotta, S, Ganga, K, GARCÍA LÁZARO, J, Garnica, A, Gaspard, M, Gavila, E, Giard, M, Giardino, G, Gienger, G, GIRAUD HERAUD, Y, Glorian, J, Griffin, M, Gruppuso, A, Guglielmi, L, Guichon, D, Guillaume, B, Guillouet, P, Haissinski, J, Hansen, F, Hardy, J, Harrison, D, Hazell, A, Hechler, M, Heckenauer, V, Heinzer, D, Hell, R, HENROT VERSILLÉ, S, HERNÁNDEZ MONTEAGUDO, C, Herranz, D, Herreros, J, Hervier, V, Heske, A, Heurtel, A, Hildebrandt, S, Hills, R, Hivon, E, Hobson, M, Hollert, D, Holmes, W, Hornstrup, A, Hovest, W, Hoyland, R, Huey, G, Huffenberger, K, Hughes, N, Israelsson, U, Jackson, B, Jaffe, A, Jaffe, T, Jagemann, T, Jessen, N, Jewell, J, Jones, W, Juvela, M, Kaplan, J, Karlman, P, Keck, F, Keihänen, E, King, M, Kisner, T, Kletzkine, P, Kneissl, R, Knoche, J, Knox, L, Koch, T, Krassenburg, M, KURKI SUONIO, H, Lähteenmäki, A, Lagache, G, Lagorio, E, Lami, P, Lande, J, Lange, A, Langlet, F, Lapini, R, Lapolla, M, Lasenby, A, LE JEUNE, M, Leahy, J, Lefebvre, M, Legrand, F, LE MEUR, G, Leonardi, R, Leriche, B, Leroy, C, Leutenegger, P, Levin, S, Lilje, P, Lindensmith, C, LINDEN VØRNLE, M, Loc, A, Longval, Y, Lubin, P, Luchik, T, Luthold, I, MACIAS PEREZ, J, Maciaszek, T, Mactavish, C, Madden, S, Maffei, B, Magneville, C, Maino, D, Mambretti, A, Mansoux, B, Marchioro, D, Maris, M, Marliani, F, Marrucho, J, MARTÍ CANALES, J, MARTÍNEZ GONZÁLEZ, E, MARTÍN POLEGRE, A, Martin, P, Marty, C, Marty, W, Masi, S, Massardi, M, Matarrese, S, Matthai, F, Mazzotta, P, Mcdonald, A, Mcgrath, P, Mediavilla, A, Meinhold, P, Mélin, J, Melot, F, Mendes, L, Mennella, A, Mervier, C, Meslier, L, Miccolis, M, MIVILLE DESCHENES, M, Moneti, A, Montet, D, Montier, L, Mora, J, Morgante, G, Morigi, G, Morinaud, G, Morisset, N, Mortlock, D, Mottet, S, Mulder, J, Munshi, D, Murphy, A, Murphy, P, Musi, P, Narbonne, J, Naselsky, P, Nash, A, Nati, F, Natoli, P, Netterfield, B, Newell, J, Nexon, M, Nicolas, C, Nielsen, P, Ninane, N, Noviello, F, Novikov, D, Novikov, I, O'Dwyer, I, Oldeman, P, Olivier, P, Ouchet, L, Oxborrow, C, PÉREZ CUEVAS, L, Pagan, L, Paine, C, Pajot, F, Paladini, R, Pancher, F, Panh, J, Parks, G, Parnaudeau, P, Partridge, B, Parvin, B, Pascual, J, Pasian, F, Pearson, D, Pearson, T, Pecora, M, Perdereau, O, Perotto, L, Perrotta, F, Piacentini, F, Piat, M, Pierpaoli, E, Piersanti, O, Plaige, E, Plaszczynski, S, Platania, P, Pointecouteau, E, Polenta, G, Ponthieu, N, Popa, L, Poulleau, G, Poutanen, T, Prézeau, G, Pradell, L, Prina, M, Prunet, S, Rachen, J, Rambaud, D, Rame, F, Rasmussen, I, Rautakoski, J, Reach, W, Rebolo, R, Reinecke, M, Reiter, J, Renault, C, Ricciardi, S, Rideau, P, Riller, T, Ristorcelli, I, Riti, J, Rocha, G, Roche, Y, Pons, R, Rohlfs, R, Romero, D, Roose, S, Rosset, C, Rouberol, S, ROWAN ROBINSON, M, RUBIÑO MARTÍN, J, Rusconi, P, Rusholme, B, Salama, M, Salerno, E, Sandri, M, Santos, D, Sanz, J, Sauter, L, Sauvage, F, Savini, G, Schmelzel, M, Schnorhk, A, Schwarz, W, Scott, D, Seiffert, M, Shellard, P, Shih, C, Sias, M, Silk, J, Silvestri, R, Sippel, R, Smoot, G, Starck, J, Stassi, P, Sternberg, J, Stivoli, F, Stolyarov, V, Stompor, R, Stringhetti, L, Strommen, D, Stute, T, Sudiwala, R, Sugimura, R, Sunyaev, R, Sygnet, J, Türler, M, Taddei, E, Tallon, J, Tamiatto, C, Taurigna, M, Taylor, D, Terenzi, L, Thuerey, S, Tillis, J, Tofani, G, Toffolatti, L, Tommasi, E, Tomasi, M, Tonazzini, E, Torre, J, Tosti, S, Touze, F, Tristram, M, Tuovinen, J, Tuttlebee, M, Umana, G, Valenziano, L, Vallée, D, VAN DER VLIS, M, VAN LEEUWEN, F, Vanel, J, VAN TENT, B, Varis, J, Vassallo, E, Vescovi, C, Vezzu, F, Vibert, D, Vielva, P, Vierra, J, Villa, F, Vittorio, N, Vuerli, C, Wade, L, Walker, A, Wandelt, B, Watson, C, Werner, D, White, M, White, S, Wilkinson, A, Wilson, P, Woodcraft, A, Yoffo, B, Yun, M, Yurchenko, V, Yvon, D, Zhang, B, Zimmermann, O, Zonca, A, Zorita, D, Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), École normale supérieure - Paris (ENS Paris)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université de Cergy Pontoise (UCP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Max-Planck-Institut für Gravitationsphysik ( Albert-Einstein-Institut ) (AEI), Physique Corpusculaire et Cosmologie - Collège de France (PCC), Collège de France (CdF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Collège de France (CdF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Department of Physics, Helsinki Institute of Physics, Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), École normale supérieure - Paris (ENS Paris), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Max-Planck-Institut für Gravitationsphysik ( Albert-Einstein-Institut ) (AEI), and Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS)
Subjects: [SDU.ASTR.CO]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], Astrophysics, general [Submillimeter], 7. Clean energy, 01 natural sciences, DESIGN, Aeronautics, CMB physics, SPACE, Space vehicles: instruments, Instrumentation: detectors, 010303 astronomy & astrophysics, detectors [Instrumentation], QB, CALIBRATION, Physics, Planck ESA mission, general [Radio continuum], Astrophysics::Instrumentation and Methods for Astrophysics, space vehicles: instrument, MICROWAVE BACKGROUND ANISOTROPY, instrumentation: polarimeter, HIGH-FREQUENCY INSTRUMENT, cosmic microwave background, Submillimeter: general, [PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], Cosmic microwawe background, education, Astrophysics::Cosmology and Extragalactic Astrophysics, instrumentation: detector, Instrumentation: polarimeters, Cosmic microwave background, [PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], instruments [Space vehicles], Radio continuum: general, Settore FIS/05 - Astronomia e Astrofisica, 0103 physical sciences, polarimeters [Instrumentation], 010308 nuclear & particles physics, Astronomy and Astrophysics, Space vehicles, PERFORMANCE, 115 Astronomy, Space science, [SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], space vehicles: instruments, instrumentation: detectors, instrumentation: polarimeters, submillimeter: general, radio continuum: general, CMB EXPERIMENTS, 13. Climate action, Space and Planetary Science, Astronautics, Aeronàutica i espai::Astronàutica [Àrees temàtiques de la UPC], Instruments, Astronàutica
Abstract: 22 páginas, 16 figuras, 6 tablas.-- Planck Science Team: et al., The European Space Agency's Planck satellite, launched on 14 May 2009, is the third-generation space experiment in the field of cosmic microwave background (CMB) research. It will image the anisotropies of the CMB over the whole sky, with unprecedented sensitivity ( ~ 2 × 10-6) and angular resolution (~5 arcmin). Planck will provide a major source of information relevant to many fundamental cosmological problems and will test current theories of the early evolution of the Universe and the origin of structure. It will also address a wide range of areas of astrophysical research related to the Milky Way as well as external galaxies and clusters of galaxies. The ability of Planck to measure polarization across a wide frequency range (30-350 GHz), with high precision and accuracy, and over the whole sky, will provide unique insight, not only into specific cosmological questions, but also into the properties of the interstellar medium. This paper is part of a series which describes the technical capabilities of the Planck scientific payload. It is based on the knowledge gathered during the on-ground calibration campaigns of the major subsystems, principally its telescope and its two scientific instruments, and of tests at fully integrated satellite level. It represents the best estimate before launch of the technical performance that the satellite and its payload will achieve in flight. In this paper, we summarise the main elements of the payload performance, which is described in detail in the accompanying papers. In addition, we describe the satellite performance elements which are most relevant for science, and provide an overview of the plans for scientific operations and data analysis.
Published: 2010

25. Postoperative swelling after orthognathic surgery: a prospective volumetric analysis.

Author: van der Vlis M, Dentino KM, Vervloet B, and Padwa BL
Subjects: Humans, Edema etiology, Orthognathic Surgical Procedures adverse effects, Postoperative Complications
Abstract: Purpose: Three-dimensional (3D) stereophotogrammetry is a reliable, accurate, and noninvasive tool for measuring changes in soft tissue volume over time. The purpose of this prospective study was to quantify changes in postoperative swelling after orthognathic surgery using serial 3D photographs., Patients and Methods: Three-dimensional photographs of 49 orthognathic surgery patients (Le Fort I and/or bilateral sagittal split osteotomy) were captured using the 3D Vectra imaging system pre-operatively (T0) and at one week (T1), two weeks (T2), three weeks (T3), four weeks (T4), six weeks (T5), three months (T6), six months (T7) and one year (T8) postoperatively. Canfield Mirror imaging software was used to quantify volume differences between serial 3D images. Descriptive statistics and repeated measures analysis of variance were calculated. Data were stratified by gender, preoperative body mass index (BMI), and procedure performed., Results: On average, 50% of the initial swelling resolved after the third postoperative week (T3), and, after 3 months (T6), only 20% of the initial edema remained. Patients with a higher BMI had the greatest amount of swelling and fastest rate of resolution in the initial weeks after the operation. Patients with a lower BMI had less postoperative edema and a slower rate of reduction between all time points. Initial swelling and resolution did not vary significantly by gender or type of malocclusion., Conclusions: Facial edema resolves rapidly during the first three post-operative weeks; significant decrease in soft tissue swelling still occurs between 6-12 months post-operatively., (Copyright © 2014 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.)
Published: 2014
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26. Cognitive and motor functioning in gene carriers for Huntington's disease: a baseline study.

Author: Witjes-Ané MN, Vegter-van der Vlis M, van Vugt JP, Lanser JB, Hermans J, Zwinderman AH, van Ommen GJ, and Roos RA
Subjects: Adolescent, Adult, Aged, Cognition Disorders genetics, Diagnosis, Differential, Female, Genetic Testing, Humans, Huntington Disease genetics, Male, Mental Status Schedule statistics & numerical data, Middle Aged, Psychometrics, Psychomotor Disorders genetics, Reaction Time genetics, Reaction Time physiology, Cognition Disorders diagnosis, Genetic Carrier Screening, Huntington Disease diagnosis, Neuropsychological Tests, Psychomotor Disorders diagnosis
Abstract: The aim of this study was to investigate the first changes in cognitive and motor functioning in Huntington's disease. Forty-six gene carriers, not clinically diagnosed for HD, were compared with 88 non-gene carriers. Gene carriers performed significantly worse on the Benton Visual Retention Test. This result was due to a minority of participants who had already developed cognitive impairment. Marginal differences appeared on the motor times of single reaction time measures after correction for motor signs. The findings are discussed in the context of inconsistencies in previous studies and underscore the need for longitudinal research.
Published: 2003
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27. Predictability of age at onset in Huntington disease in the Dutch population.

Author: Maat-Kievit A, Losekoot M, Zwinderman K, Vegter-van der Vlis M, Belfroid R, Lopez F, Van Ommen GJ, Breuning M, and Roos R
Subjects: Adolescent, Adult, Age of Onset, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Humans, Huntington Disease genetics, Infant, Male, Middle Aged, Netherlands, Repetitive Sequences, Amino Acid, Retrospective Studies, Huntington Disease epidemiology
Published: 2002
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28. Using a roster and haplotyping is useful in risk assessment for persons with intermediate and reduced penetrance alleles in Huntington disease.

Author: Maat-Kievit A, Helderman-van den Enden P, Losekoot M, de Knijff P, Belfroid R, Vegter-van der Vlis M, Roos R, and Breuning M
Subjects: Age of Onset, DNA genetics, Family Health, Female, Gene Frequency, Haplotypes, Humans, Huntingtin Protein, Male, Nerve Tissue Proteins genetics, Nuclear Proteins genetics, Pedigree, Penetrance, Registries, Risk, Trinucleotide Repeats genetics, Alleles, Huntington Disease genetics
Abstract: The risk of a person having a child with an inherited disorder, caused by an unstable triplet repeat, such as Huntington disease (HD), depends on the expansion of the mutation in that person, which is connected both to the biological nature of the mutation and to the person's relation to the carrier of the full mutation. Once the mutation causing HD was identified, we were able to diagnose sporadic patients. A sporadic patient can sometimes be connected to a known HD pedigree by using a roster. By haplotyping and calculating the posterior identity-by-descent probability, we could establish whether a connection was coincidental or not. Furthermore, we describe the frequency of intermediate and reduced penetrance alleles detected. Using the family history and the roster to search for a connection, we examined whether these alleles were on the HD haplotype of a family. It is important to know the origin of an intermediate or reduced penetrance allele because if it comes from an HD branch of the family or from the non-HD affected side of the pedigree, different risks for relatives and penetrance ensue. In our study, most intermediate alleles came from the non-HD-affected side of the pedigree and had a repeat size in the lower range with a negligible risk for expansion. Intermediate alleles on the HD haplotypes were larger and found in predictive test applicants from known families or relatives from new mutations with a higher risk for expansion. Reduced penetrance alleles in the higher range were mainly found in symptomatic and predictive test applicants from known families, with a considerable risk for penetrance, although at older age. We conclude that a roster, a thorough family history, and haplotyping in persons with intermediate and reduced penetrance alleles are essential in considering the risk of a person having (a child with) HD., (Copyright 2001 Wiley-Liss, Inc.)
Published: 2001
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29. Predictive testing of 25 percent at-risk individuals for Huntington disease (1987-1997).

Author: Maat-Kievit A, Vegter-Van Der Vlis M, Zoeteweij M, Losekoot M, van Haeringen A, and Roos RA
Subjects: Adult, Decision Trees, Female, Genetic Counseling methods, Genetic Counseling psychology, Guilt, Heterozygote, Humans, Huntington Disease mortality, Huntington Disease psychology, Informed Consent, Male, Middle Aged, Mutation genetics, Netherlands, Nuclear Family, Pedigree, Practice Guidelines as Topic, Reproducibility of Results, Truth Disclosure, Genetic Predisposition to Disease genetics, Genetic Predisposition to Disease psychology, Genetic Testing methods, Genetic Testing psychology, Huntington Disease genetics
Abstract: Before the mutation causing Huntington disease was identified, predictive testing of 25% at-risk persons with a 50% at-risk parent who did not wish to know his/her genetic status, was only possible by exclusion testing. The exclusion test, using linked markers, ensures the parent's wish not to know because the parent's risk is not changed. When mutation analysis became available in 1993, new testing options for 25% at-risk persons emerged: viz., the exclusion-definitive test and direct mutation analysis. These new tests not only disclose the risk of the test candidate, but may also change the risk of the at-risk parent and siblings. The testing options for 25% at-risk test applicants and their consequences are discussed and the testing procedures and results of testing 64 25% at-risk persons in the period 1987 to 1997 are described. Relatives received unsought information in 56% of the test procedures before and 34% after the mutation was identified. A decision tree and guidelines for predictive testing of 25% at-risk test applicants are proposed. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 88:662-668, 1999., (Copyright 1999 Wiley-Liss, Inc.)
Published: 1999
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30. Two centuries of mortality in ten large families with Huntington disease: a rising impact of gene carriership.

Author: Hille ET, Siesling S, Vegter-van der Vlis M, Vandenbroucke JP, Roos RA, and Rosendaal FR
Subjects: Adult, Aged, Female, Humans, Life Expectancy, Male, Middle Aged, Netherlands epidemiology, Heterozygote, Huntington Disease genetics, Huntington Disease mortality
Abstract: To estimate the impact of the Huntington gene on mortality, we studied ten families with Huntington disease, whose records started before 1800. We investigated mortality from 1800 to 1997 in 257 carriers of the Huntington gene and 474 potential carriers. Follow-up extended from age 20 years to the date of death or end-of-study date. The observed deaths were compared with those expected on the basis of the general population, adjusted for sex, age, and calendar time. To study the influence of the family and parental transmission, we calculated hazard ratios adjusted for sex, probability of carrying the gene, and year of birth. In 25,013 person-years, 420 deaths occurred, whereas 278 deaths were expected [standardized mortality ratio = 1.5; 95% confidence interval (CI) = 1.4-1.7]. Excess mortality was confined to ages 40-70 years (standardized mortality ratio = 2.2; 95% CI = 1.9-2.4). To study the evolution of mortality over time in this age group, we calculated absolute mortality rates per calendar period. From 1800 onward, mortality rates in the general population continuously declined, but among the families with Huntington disease this decline was absent. There were only small differences in risk between families, and the relative risk for paternal over maternal transmission was 1.2 (95% CI = 0.9-1.5). Our main finding is that persons who carry the Huntington gene and reach middle age have not benefited from advances in medical care and overall increase in life expectancy.
Published: 1999

31. Experience in prenatal testing for Huntington's disease in The Netherlands: procedures, results and guidelines (1987-1997).

Author: Maat-Kievit A, Vegter-van der Vlis M, Zoeteweij M, Losekoot M, van Haeringen A, Kanhai H, and Roos R
Subjects: Adult, Female, Guidelines as Topic, Humans, Huntington Disease embryology, Male, Netherlands, Predictive Value of Tests, Pregnancy, Fetal Diseases diagnosis, Genetic Counseling, Huntington Disease diagnosis, Prenatal Diagnosis standards
Abstract: We have performed 31 exclusion tests (43 per cent) and 41 direct tests (57 per cent) in 43 couples at risk, in the period 1987 to 1997 in Leiden, The Netherlands. This resulted in termination of 28 pregnancies (39 per cent), with an increased risk. In 28 couples (65 per cent), the woman was at risk. Prenatal testing in consecutive pregnancies (mean number: 3) was performed in 15 couples (35 per cent), with a mean time interval of 15 months. Parents should make an independent choice for (every) pregnancy, although most (86 per cent) did not change their initial choice. It is important that the position of children in the same family, of whom some know their status as a result of prenatal testing, whereas others remain at risk, is taken into consideration in counselling. The relative number of exclusion tests when compared with direct tests has diminished since the mutation was identified. The prenatal exclusion-definitive test (Fig. 1) was rarely used (2/72, 3 per cent). Nowadays, direct mutation testing of the fetus only is simpler and faster and the risk of disclosure of the genetic status of the at-risk parent is only 25 per cent. This test should therefore be offered as another option and included in the international guidelines. The uptake for prenatal testing is low: for 2 per cent of the at-risk persons, 11 per cent of the tested carriers and a small group of at-risk persons wishing not to be tested themselves, prenatal testing seems an acceptable choice regarding reproduction.
Published: 1999

32. Juvenile Huntington disease in the Netherlands.

Author: Siesling S, Vegter-van der Vlis M, and Roos RA
Subjects: Adolescent, Adult, Child, Cross-Sectional Studies, Female, Humans, Huntington Disease diagnosis, Huntington Disease epidemiology, Huntington Disease mortality, Incidence, Life Tables, Male, Muscle Rigidity diagnosis, Muscle Rigidity epidemiology, Muscle Rigidity genetics, Muscle Rigidity mortality, Netherlands epidemiology, Neurologic Examination, Risk Factors, Survival Analysis, Huntington Disease genetics
Abstract: Juvenile Huntington disease (JHD) patients are distinguished from adult patients by an age at onset of less than 20 years. Investigating patients in our own database, we examined the proposition derived from studies in world literature that JHD should not be viewed as a separate clinical entity but rather as a manifestation of the rigid variant of the disease. Of 53 patients with JHD recorded in the Leiden Roster for Huntington Disease, relationships between sex, age at onset, duration of illness, maternal or paternal inheritance, motor symptom, first clinical features, and characteristics during the disease course, were obtained from the patients' files, and investigated. Although chorea is present in JHD, patients more often developed rigidity. Paternal inheritance, early dementia, epilepsy/myoclonus, and tremor during the disease course are confined for the most part to the rigid cases. A shorter duration of illness was evident in male patients with rigid JHD who inherited the disease from their father and developed their first disease feature at a younger age. The recognition of JHD as a distinct clinical entity does not appear to be warranted. Therefore, we propose, in accordance with other investigators, that rigid JHD be considered a clinical variant with special features.
Published: 1997
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33. Presymptomatic DNA testing for Huntington disease: identifying the need for psychological intervention.

Author: Tibben A, Duivenvoorden HJ, Vegter-van der Vlis M, Niermeijer MF, Frets PG, van de Kamp JJ, Roos RA, Rooijmans HG, and Verhage F
Subjects: Adult, Denial, Psychological, Follow-Up Studies, Humans, Huntington Disease psychology, Predictive Value of Tests, Prognosis, Psychological Tests, Risk Factors, Social Support, Attitude to Health, Genetic Testing, Huntington Disease genetics
Abstract: Unlabelled: In the Dutch presymptomatic DNA-testing program for Huntington disease (HD), 29 individuals with increased risk and 44 with decreased risk were followed-up 6 months after test results. A prognostic model was built aimed at identifying individuals at risk for psychological maladjustment, as measured by the Impact of Event Scale, the Beck Hopelessness Scale, the General Health Questionnaire, and the Social Support Questionnaire., Results: 1) The more that applicants suffered from intrusive feelings about HD and tried to avoid HD-related situations, prior to the test, the greater the chance that they will experience this 6 months after the test if they proved to be at increased risk; 2) the more that both individuals with increased risk and those with decreased risk who suffered from the threat of having HD tried to avoid HD-related situations prior to the test and the less satisfied they were with available support, the greater the probability that they will show avoidance behavior after the test; 3) the more pessimistic that individuals with increased risk as well as those with decreased risk were about their future prior to the test, the more they avoided HD-related situations and the more dissatisfied they were about their available support (pretest), the greater the probability that they will become depressive and suicidal. Psychological adjustment was also studied as a function of a) intrusion/denial-avoidance pattern over time and b) healthy mental functioning/future expectancies. Most individuals with increased risk (86%) seem to cope well thus far, although this was based largely on strong psychological defenses and dependent on satisfactory relationships.(ABSTRACT TRUNCATED AT 250 WORDS)
Published: 1993
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34. Defining the proximal border of the Huntington disease candidate region by multipoint recombination analyses.

Author: Skraastad MI, de Rooij KE, de Koning Gans PA, Verwest A, Vegter-van der Vlis M, Bakker E, den Dunnen JT, and van Ommen GB
Subjects: Female, Genetic Markers, Humans, Male, Pedigree, Polymorphism, Genetic, Recombination, Genetic, Chromosome Mapping, Chromosomes, Human, Pair 4, Huntington Disease genetics
Abstract: The candidate region for the Huntington disease (HD) gene has been narrowed down to a 2.2-Mb region between D4S10 and D4S98 on the short arm of chromosome 4. To map the HD gene within this candidate region 65 Dutch HD families were studied. In total 338 informative meioses were analyzed and 11 multiple informative crossovers were detected. Assuming a minimum number of recombinations and no double recombinations, our multiple informative crossovers are consistent with one specific genetic order for 12 loci: D4S10-(D4S81, D4S126)-D4S125-(D4S127,D4S95)-D4S43-(D4 S115, D4S96, D4S111, D4S90, D4S141). This is in agreement with the known data derived from similar and other methods. The loci between brackets could not be mapped relative to each other. In our family material, two informative three-point marker recombination events were detected in the proximal HD candidate region, which are also informative for HD. Both recombination events map the HD gene distal to D4S81 and most likely distal to D4S125, narrowing down the HD candidate region to a 1.7-Mb region between D4S125 and D4S98.
Published: 1993
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35. Presymptomatic DNA-testing for Huntington disease: pretest attitudes and expectations of applicants and their partners in the Dutch program.

Author: Tibben A, Frets PG, van de Kamp JJ, Niermeijer MF, Vegter-van der Vlis M, Roos RA, van Ommen GJ, Duivenvoorden HJ, and Verhage F
Subjects: Adult, Clinical Laboratory Techniques, Cohort Studies, Family Planning Services, Female, Health Status, Humans, Huntington Disease diagnosis, Huntington Disease genetics, Male, Marriage, Middle Aged, Netherlands, Prospective Studies, Risk Factors, Attitude to Health, Huntington Disease psychology
Abstract: We studied the baseline attitudes, prior to testing, of 70 applicants at risk for Huntington disease (HD) and their partners in the Dutch presymptomatic DNA-testing program. Two thirds of the applicants were female; 36% already had children. The main reason (60%) for undertaking the test was for family planning. Other reasons were either to reduce uncertainty (43%) or to obtain certainty (38%). Partners of applicants stated that planning for the future was for them the most important reason (76%). Significantly more at-risk females (42%) than males (16%) anticipated an unfavorable test outcome. Quite remarkably, most applicants and partners denied that a positive result might have adverse effects on either personal mood, quality of life, or marriage. Only a few did not expect that a favorable result would induce relief. The eventual outcome of the test was expected to enable applicants to gain control over their future, whatever the results. Hence, we propose that the applicants form a self-selected group, based on their expectation that they will not be emotionally affected by either result.
Published: 1993
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36. Significant linkage disequilibrium between the Huntington disease gene and the loci D4S10 and D4S95 in the Dutch population.

Author: Skraastad MI, Van de Vosse E, Belfroid R, Höld K, Vegter-van der Vlis M, Sandkuijl LA, Bakker E, and van Ommen GJ
Subjects: Alleles, DNA isolation & purification, Genetic Markers, Haplotypes, Humans, Huntington Disease epidemiology, Netherlands epidemiology, Restriction Mapping, DNA genetics, Genetic Linkage, Huntington Disease genetics
Abstract: Significant linkage disequilibrium has been found between the Huntington disease (HD) gene and DNA markers located around D4S95 and D4S98. The linkage-disequilibrium studies favor the proximal location of the HD gene, in contrast to the conflicting results of recombination analyses. We have analyzed 45 Dutch HD families with 19 DNA markers and have calculated the strength of linkage disequilibrium. Highly significant linkage disequilibrium has been detected with D4S95, consistent with the studies in other populations. In contrast with most other studies, however, the area of linkage disequilibrium extends from D4S10 proximally to D4S95, covering 1,100 kb. These results confirm that the HD gene most likely maps near D4S95.
Published: 1992

37. DNA-testing for Huntington's disease in The Netherlands: a retrospective study on psychosocial effects.

Author: Tibben A, Vegter-van der Vlis M, Skraastad MI, Frets PG, van der Kamp JJ, Niermeijer MF, van Ommen GJ, Roos RA, Rooijmans HG, and Stronks D
Subjects: Adult, Female, Genetic Carrier Screening, Humans, Huntington Disease genetics, Huntington Disease psychology, Male, Netherlands, Retrospective Studies, DNA genetics, Huntington Disease diagnosis
Abstract: Presymptomatic DNA-testing for Huntington's disease has made it possible to predict whether or not at-risk individuals are gene-carriers with a reliability of about 98%. In our retrospective study of 18 tested individuals, most of the newly identified carriers function apparently well. They use avoidance and repression of affect as psychological defense strategies. However, 8 out of 9 non-carriers do not experience the expected relief about their test results. They experience survivor guilt and emotional numbness and find it difficult to cope with the effects of the test results on the family system. The partners of gene-carriers are at risk of becoming emotionally isolated by putting aside their own feelings for fear of seeming self-centered. Appreciation of these effects on tested individuals is important and professional support is needed to prevent post-traumatic stress disorders. Whatever the test result may be, the working through process may take years rather than months. These findings have important implications for patient care and necessitate an extended period of observation after presymptomatic testing.
Published: 1992
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38. Presymptomatic, prenatal, and exclusion testing for Huntington disease using seven closely linked DNA markers.

Author: Skraastad MI, Verwest A, Bakker E, Vegter-van der Vlis M, van Leeuwen-Cornelisse I, Roos RA, Pearson PL, and van Ommen GJ
Subjects: DNA genetics, Evaluation Studies as Topic, Female, Genetic Counseling, Genetic Markers, Humans, Huntington Disease genetics, Pedigree, Pregnancy, Prenatal Diagnosis, Huntington Disease diagnosis
Abstract: Presymptomatic, testing, prenatal diagnosis, or exclusion testing are now available for persons at risk for Huntington disease. These tests will reduce uncertainty, assist in life planning, and prevent the birth of potentially affected children. We present the results of presymptomatic tests for 37 applicants including two prenatal and one exclusion test in 23 families. We initially used the markers G8, H5.52, F5.53, and pTV20 (D4S10), p8 (D4S62), and pRB1.6 (D4S81) and extended the informativity of the test at a later stage with the markers pKP1.65, C4H, S1.5 (D4S43), 674 (D4S95), 157.9 (D4S111), and YNZ32 (D4S125). Applicants with an unsuitable family structure were not admitted to the test. Of the 37 applicants, 33 were informative. In our hands the most efficient strategy is first to use the markers H5.52 (D4S10), pRB1.6 (D4S81), 674 (D4S95), pKP1.65 (D4S43), 157.9 (D4S111), YNZ32 (D4S125), and 252.3 (D4S115). The overall informativity in our data set was 84% and in the most recent test we achieved a 90-95% informativity. The other markers are used only when the first set is not informative.
Published: 1991
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39. Hereditary cerebral haemorrhage with amyloidosis--Dutch type. Magnetic resonance imaging findings in 7 cases.

Author: Haan J, Roos RA, Algra PR, Lanser JB, Bots GT, and Vegter-Van der Vlis M
Subjects: Adult, Brain pathology, Female, Genetic Diseases, Inborn diagnosis, Humans, Male, Middle Aged, Netherlands, Neuropsychological Tests, Pedigree, Amyloidosis diagnosis, Cerebral Hemorrhage diagnosis, Magnetic Resonance Imaging
Abstract: The clinical history and magnetic resonance imaging (MRI) findings are presented of 7 patients with hereditary cerebral haemorrhage with amyloidosis--Dutch type (HCHWA-D). The diagnosis was based on clinical and genealogical data, was confirmed in 3 patients at autopsy and in 2 others by biopsy. Focal neurological signs, and at least some degree of global cognitive deterioration, were observed in all patients, with unequivocal dementia in 4. MRI showed haemorrhages and areas of gliosis and, to a variable extent, hyperintensity of the white matter in T2-weighted images. Neuropathological examination revealed a large recent haemorrhage together with residual lesions from previous haemorrhages or infarcts in all patients examined. The white matter lesions, present on MRI, turned out to be areas of 'incomplete infarction' with demyelination. It is concluded that (hereditary) amyloid angiopathy can lead to strokes, but also to subcortical ischaemic encephalopathy. Amyloid angiopathy should therefore be considered in the differential diagnosis of white matter lesions, found on CT or MRI, especially when patients present with a cerebral haemorrhage. The relationship between HCHWA-D and Alzheimer's disease, another disease with cerebral amyloid deposition and diffuse white matter involvement, is discussed.
Published: 1990
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40. [Procedure and initial results of presymptomatic DNA studies in Huntington's chorea].

Author: Roos RA, Vegter-van der Vlis M, Tibben A, Skraastad MI, and Pearson PL
Subjects: Adolescent, Adult, Female, Genetic Markers analysis, Humans, Male, Middle Aged, Pedigree, Reproducibility of Results, DNA analysis, Genetic Carrier Screening, Huntington Disease genetics
Abstract: The availability of DNA-markers more tightly linked to the Huntington's disease locus made presymptomatic and exclusion testing possible with an accuracy of up to 98%. The testing programme started in Leiden in August 1987. In 56 adults with 25% and 50% risks presymptomatic tests were performed. In 8 persons the risk was increased to 98%, in 17 it was decreased to less than 5%. In two instances the test was not informative. The remaining 29 persons have not yet been tested for different reasons. So far 3 exclusion tests were requested: one showed a decreased risk, one has not yet been performed and one request was rejected. The results and the reactions to the test are discussed.
Published: 1990

41. [Presymptomatic DNA diagnosis in Huntington's chorea: reactions to the certainty of not being a genetic carrier].

Author: Tibben A, Vegter-van der Vlis M, Roos RA, van de Kamp JJ, Frets PG, and Verhage F
Subjects: Adult, Anger, Female, Genetic Techniques psychology, Humans, Huntington Disease diagnosis, Sibling Relations, DNA analysis, Genetic Carrier Screening, Guilt, Huntington Disease genetics
Abstract: Presymptomatic DNA diagnostics in Huntington's chorea make it possible to establish with approx. 98% certainty whether an at-risk person is a gene carrier. Sympathy and care are usually shown to those demonstrated to have the gene and so will become affected in the future. Persons shown not to be carriers sometimes do not experience the expected relief. The authors successively discuss the effects of a favourable finding on the family system, such as survivor's guilt and emotional numbing as aspects of a coping process. It is concluded that even a favourable finding needs to be worked through, a process that takes years rather than months.
Published: 1990

42. Genetic linkage studies in Huntington's chorea.

Author: Volkers WS, Went LN, Vegter-Van Der Vlis M, Harper PS, and Caro A
Subjects: Adult, England, Female, Genetic Markers, Humans, Lod Score, Male, Netherlands, Wales, Genetic Linkage, Huntington Disease genetics
Published: 1980
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43. Ages of death of children with Huntington's chorea and of their affected parents.

Author: Vegter-van der Vlis M, Volkers WS, and Went LN
Subjects: Adolescent, Adult, Age Factors, Aged, Child, Female, Genes, Humans, Huntington Disease genetics, Male, Middle Aged, Sex Factors, Huntington Disease mortality
Abstract: Bird et al. (1974) noted an interesting 'anticipation' phenomenon in Huntington's Chorea occurring in patients who inherited the gene from their father. More extensive samples from 165 pedigrees in the Low Countries permitted us to show that most of this apparent 'anticipation' is an artifact due to sampling biases related to the year of birth categories of the affected parents. When these biases were excluded no differences exist between the ages of death of affected mothers and their affected children, but a small difference of approximately two years remains between affected fathers and their affected children. This is explainable by the observation that juvenile cases of Huntington's Chorea usually have inherited the abnormality from their father.
Published: 1976
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44. Huntington's Chorea in the Netherlands. The problem of genetic heterogeneity.

Author: Went LN, Vegter-van der Vlis M, Bruyn GW, and Volkers WS
Subjects: Adult, Age Factors, Aged, Female, Humans, Life Expectancy, Male, Middle Aged, Netherlands, Huntington Disease genetics
Abstract: For 1100 patients with Huntington's Chorea in 102 families from The Netherlands the average age at death per family is presented. This average ranges from 72 to 38 years. An analysis of variance of the data is strongly indicative of genetic heterogeneity. For the patients with the relatively high age at death little or no difference is observed from the age at death of their non-affected parents and non-affected sibs. Eleven children who presented with the juvenile form of the disease had all inherited the abnormal gene from their father. These 11 children were found only in families with an average age at death below 57 years. Other factors that might possibly influence the variation of average age at death between families are discussed, but cannot explain the observed differences.
Published: 1983
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45. Epidemiological and clinical aspects of hereditary cerebral hemorrhage in Dutch families.

Author: Luyendijk W, Bots GT, Vegter-van der Vlis M, and Went LN
Subjects: Adult, Aged, Cerebral Hemorrhage drug therapy, Cerebral Hemorrhage epidemiology, Epidemiologic Methods, Humans, Middle Aged, Netherlands, Cerebral Hemorrhage genetics
Published: 1987
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46. Mapping of recombinants near the Huntington disease locus by using G8 (D4S10) and newly isolated markers in the D4S10 region.

Author: Skraastad MI, Bakker E, de Lange LF, Vegter-van der Vlis M, Klein-Breteler EG, van Ommen GJ, and Pearson PL
Subjects: Chromosome Mapping, Haplotypes, Humans, Netherlands ethnology, Polymorphism, Restriction Fragment Length, Recombination, Genetic, Restriction Mapping, Chromosomes, Human, Pair 4, DNA Probes, Huntington Disease genetics
Abstract: Genetic linkage between the marker G8 (D4S10) and Huntington disease (HD) was studied in six Dutch pedigrees. The informativeness of the D4S10 locus was increased by isolation of a cosmid, C5.5, with a G8 subclone used as probe. We present a restriction map of 70 kb in the D4S10 region. Two subclones of C5.5, H5.52 and F5.53, detect MspI and SinI RFLPs, respectively. These probes increase the informativeness of D4S10 in the Dutch HD population from 55% to 95%. Seven recombinations were found in 124 informative meioses in which multipoint segregation of D4S10 haplotypes and the HD locus was studied. Two of the recombinations occurred within the D4S10 region. The other five recombinations are highly valuable for the mapping of present and future markers relative to each other and to the HD gene. In addition, several recombinations between markers in meioses from unaffected parents were noted, which will also be useful in ordering new markers. On the basis of our three-point recombination data, the orientation of the D4S10 region relative to HD is HD-H5.52-G8-F5.53, which independently confirms the previously derived polarity for D4S10.
Published: 1989

47. [Familial cerebral hemorrhage as a result of cerebral amyloid angiopathy].

Author: Luyendijk W, Bots GT, Vegter-van der Vlis M, and Went LN
Subjects: Aged, Amyloidosis complications, Cerebral Hemorrhage etiology, Cerebral Hemorrhage pathology, Chromosome Aberrations genetics, Chromosome Disorders, Female, Genes, Dominant, Humans, Intracranial Arteriosclerosis etiology, Male, Middle Aged, Pedigree, Amyloidosis genetics, Cerebral Hemorrhage genetics, Intracranial Arteriosclerosis genetics
Published: 1986

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