Search

Your search keyword '"Uvere, Ezinne"' showing total 168 results
Start Over Author "Uvere, Ezinne"
168 results on '"Uvere, Ezinne"'

1. Novel functional insights into ischemic stroke biology provided by the first genome-wide association study of stroke in indigenous Africans

Author

Akinyemi, Rufus O., Tiwari, Hemant K., Srinivasasainagendra, Vinodh, Akpa, Onoja, Sarfo, Fred S., Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Osaigbovo, Godwin O., Mamaeva, Olga A., Halloran, Brian A., Akinyemi, Joshua, Lackland, Daniel, Obiabo, Olugbo Y., Sunmonu, Taofik, Chukwuonye, Innocent I., Arulogun, Oyedunni, Jenkins, Carolyn, Adeoye, Abiodun, Agunloye, Atinuke, Ogah, Okechukwu S., Ogbole, Godwin, Fakunle, Adekunle, Uvere, Ezinne, Coker, Motunrayo M., Okekunle, Akinkunmi, Asowata, Osahon, Diala, Samuel, Ogunronbi, Mayowa, Adeleye, Osi, Laryea, Ruth, Tagge, Raelle, Adeniyi, Sunday, Adusei, Nathaniel, Oguike, Wisdom, Olowoyo, Paul, Adebajo, Olayinka, Olalere, Abimbola, Oladele, Olayinka, Yaria, Joseph, Fawale, Bimbo, Ibinaye, Philip, Oyinloye, Olalekan, Mensah, Yaw, Oladimeji, Omotola, Akpalu, Josephine, Calys-Tagoe, Benedict, Dambatta, Hamisu A., Ogunniyi, Adesola, Kalaria, Rajesh, Arnett, Donna, Rotimi, Charles, Ovbiagele, Bruce, and Owolabi, Mayowa O.

Published
2024
Full Text
View/download PDF

2. ACHIEVE conference proceedings: implementing action plans to reduce and control hypertension burden in Africa

Author

Olowoyo, Paul, Dzudie, Anastase, Okekunle, Akinkunmi Paul, Obiako, Reginald, Mocumbi, Ana, Beheiry, Hind, Parati, Gianfranco, Lackland, Daniel T., Sarfo, Fred S., Odili, Augustine, Adeoye, Abiodun M., Wahab, Kolawole, Agyemang, Charles, Campbell, Norman, Kengne, Andre Pascal, Whelton, Paul K., Pellicori, Pierpaolo, Ebenezer, Ad Adams, Adebayo, Oladimeji, Olalusi, Oladotun, Jegede, Ayodele, Uvere, Ezinne, Adebajo, Olayinka, Awuah, Baffour, Moran, Andrew, Williams, Bryan, Guzik, Tomasz J., Kokuro, Collins, Bukachi, Fred, Ogah, Okechukwu S., Delles, Christian, Maffia, Pasquale, Akinyemi, Rufus, Barango, Prebo, Ojji, Dike, and Owolabi, Mayowa

Published
2024
Full Text
View/download PDF

3. Clinical and neuroimaging factors associated with 30-day fatality among indigenous West Africans with spontaneous intracerebral hemorrhage

Author

Komolafe, Morenikeji A., Sunmonu, Taofiki, Akinyemi, Joshua, Sarfo, Fred S., Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Owolabi, Lukman, Osaigbovo, Godwin O., Ogbole, Godwin, Tiwari, Hemant K., Jenkins, Carolyn, Lackland, Daniel T., Fakunle, Adekunle G., Uvere, Ezinne, Akpa, Onoja, Dambatta, Hamisu A., Akpalu, Josephine, Onasanya, Akinola, Olaleye, Adeniji, Ogah, Okechukwu S., Isah, Sulaiman Y., Fawale, Micheal B., Adebowale, Akintunde, Okekunle, Akinkunmi P., Arnett, Donna, Adeoye, Abiodun M., Agunloye, Atinuke M., Bello, Abiodun H., Aderibigbe, Adeniyi S., Idowu, Ahmed O., Sanusi, Ahmad A., Ogunmodede, Adebimpe, Balogun, Simon A., Egberongbe, Adedeji A., Rotimi, Folorunso T., Fredrick, Adeyemi, Akinnuoye, Andrew O., Adeniyi, Folu A., Calys-Tagoe, Benedict, Adebayo, Philip, Arulogun, Oyedunni, Agbogu-Ike, Obiageli U., Yaria, Joseph, Appiah, Lambert, Ibinaiye, Philip, Singh, Arti, Adeniyi, Sunday, Olalusi, Oladotun, Mande, Aliyu, Balogun, Olayemi, Akinyemi, Rufus, Ovbiagele, Bruce, and Owolabi, Mayowa

Published
2024
Full Text
View/download PDF

4. Pragmatic solutions to reduce the global burden of stroke: a World Stroke Organization–Lancet Neurology Commission

Author

Feigin, Valery L, Abd-Allah, Foad, Akinyemi, Rufus O, Bhattacharjee, Natalia V, Brainin, Michael, Cao, Jackie, Caso, Valeria, Dalton, Bronte, Davis, Alan, Dempsey, Robert, Duprey, Joseph, Feng, Wuwei, Ford, Gary A, Gall, Seana, Gandhi, Dorcas, Good, David C, Hachinski, Vladimir, Hacke, Werner, Hankey, Graeme J, Ishida, Marie, Johnson, Walter, Kim, Julie, Lavados, Pablo, Lindsay, Patrice, Mahal, Ajay, Martins, Sheila, Murray, Christopher, Nguyen, Thuy Phuong, Norrving, Bo, Olaiya, Muideen T, Olalusi, Oladotun V, Pandian, Jeyaraj, Phan, Hoang, Platz, Thomas, Ranta, Anna, Rehman, Sabah, Roth, Greg, Sebastian, Ivy Anne, Smith, Amanda E, Suwanwela, Nijasri C, Sylaja, P N, Thapa, Rajshree, Thrift, Amanda G, Uvere, Ezinne, Vollset, Stein Emil, Yavagal, Dileep, Yaria, Joseph, Owolabi, Mayowa O, Abera, Semaw Ferede, Akinyemi, Rufus, Dempsey, Robert J, Ibrahim, Norlinah Mohamed, Liu, Liping, Ovbiagele, Bruce, Piradov, Michael, Suwanwela, Nijasri, Abanto, Carlos, Addissie, Adamu, Adeleye, Amos O, Adilbekov, Yerzhan, Adilbekova, Bibigul, Adoukonou, Thierry A, Aguiar de Sousa, Diana, Akhmetzhanova, Zauresh, Akpalu, Albert, El Alaoui-Faris, Mustapha, Ameriso, Sebastian F, Andonova, Silva, Arsovska, Anita, Awoniyi, Folorunso E, Bakhiet, Moiz, Barboza, Miguel A, Basri, Hamidon, Bath, Philip M, Bereczki, Daniel, Beretta, Simone, Berkowitz, Aaron L, Bernhardt, Julie, Berzina, Guna, Bhavsar, Bhavan, Bisharyan, Mher S, Bohara, Manoj, Bovet, Pascal, Budincevic, Hrvoje, Cadilhac, Dominique A, Čerimagić, Denis, Charway-Felli, Augustina, Chen, Christopher, Chin, Jerome H, Christensen, Hanne, Chwojnicki, Kamil, Conforto, Adriana B, Correia, Manuel, Mora Cuervo, Daissy L, Członkowska, Anna, D'Amelio, Marco, Danielyan, Kristine E, Davis, Stephen, Demarin, Vida, Demchuk, Andrew M, Dichgans, Martin, Dokova, Klara, Donnan, Geoffrey, Duran, Juan Carlos, Ekeng, Gloria, Elkind, Mitchell S, Endres, Matthias, Fischer, Urs, Flomin, Yuriy, Gankpe, Fortuné, Gavidia, Martin, Gaye Saavedra, Andrés, Gebreyohanns, Mehari, George, Mary, Gierlotka, Marek, Giroud, Maurice, Gnedovskaya, Elena V, Gonçalves, Ivete Pillo, Gongora-Rivera, Fernando, Gunaratne, Padma S, Hamadeh, Randah R, Hamzat, Tal-hatu K, Heldner, Mirjam R, Ibrahim, Etedal, Ihle-Hansen, Hanne, Jee, Sungju, Jiann-Shing, Jeng, Johnston, S Clay, Jovanovic, Dejana, Jurjāns, Kristaps, Kalani, Rizwan, Kalkonde, Yogeshwar, Kamenova, Saltanat, Karaszewski, Bartosz, Kelly, Peter, Kiechl, Stefan, Kondybayeva, Aida, Kõrv, Janika, Kozera, Grzegorz, Kravchenko, Michael, Krespi, Yakup, Krishnamurthi, Rita, Kruja, Jera, Kutluk, Kursad, Langhorne, Peter, Law, Zhe K, Lebedynets, Dmytro, Lee, Tsong-Hai, Leung, Thomas W, Liebeskind, David S, López-Jaramillo, Patricio, Lotufo, Paulo A, Machline-Carrion, M Julia, Maia, Luis F, Malojcic, Branko, Markus, Hugh S, Marquez-Romero, Juan M, Medina, Marco T, Medukhanova, Sabina, Mehndiratta, Man Mohan, Miglāne, Evija, Mihejeva, Illa, Mikulik, Robert, Mirrakhimov, Erkin, Mohl, Stephanie, Munakomi, Sunil, Murphy, Sean, Musa, Kamarul I, Nasreldein, Ahmed, Nogueira, Raul G, Nolte, Christian H, Noubiap, Jean Jacques, Novarro-Escudero, Nelson, Ocampo, Cassandra, O'Donnell, Martin, Ogun, Yomi, Ogunniyi, Adesola, Oraby, Mohammed I, Ōrken, Dilek N, Ōzdemir, Atilla O, Ozturk, Serefnur, Paccot, Mélanie, Pereira, Telmo, Peeters, André, Potpara, Tatjana, Proios, Hariklia, Rathore, Farooq A, Sacco, Ralph L, Sahathevan, Ramesh, Sandset, Else S, Renato Santos, Irving, Saposnik, Gustavo, Sarfo, Fred S, Sargento-Freitas, João, Sharma, Mukul, Shaw, Louise, Sheth, Kevin N, Shin, Yong-Il, Shobhana, A, Silva, S Nishan, Tedim Cruz, Vitor, Thakur, Kiran, Thapa, Lekh Jung, Toni, Danilo, Topcuoglu, Mehmetakif A, Torales, Julio, Towfighi, Amytis, Truelsen, Thomas, Tsiskaridze, Alexander, Tulloch-Reid, Marshall, Useche, Juan N, Vanacker, Peter, Vassilopoulou, Sophia, Vukorepa, Gorana, Vuletic, Vladimira, Wahab, Kolawole W, Wang, Wenzhi, Wijeratne, Tissa, Wojtyniak, Bogdan, Wolfe, Charles, Yacouba, Mapoure N, Yang, Jie, Yifru, Yared M, Yock-Corrales, Adriana, Yonemoto, Naohiro, Yperzeele, Laetitia, and Zagożdżon, Pawel

Published
2023
Full Text
View/download PDF

5. Patient-level and system-level determinants of stroke fatality across 16 large hospitals in Ghana and Nigeria: a prospective cohort study

Author

Sarfo, Fred S, Akpa, Onoja M, Ovbiagele, Bruce, Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Ogbole, Godwin, Fakunle, Adekunle, Okekunle, Akinkunmi Paul, Asowata, Osahon J, Calys-Tagoe, Benedict, Uvere, Ezinne O, Sanni, Taofeek, Olowookere, Samuel, Ibinaiye, Philip, Akinyemi, Joshua O, Arulogun, Oyedunni, Jenkins, Carolyn, Lackland, Daniel T, Tiwari, Hemant K, Isah, Suleiman Y, Abubakar, Sani A, Oladimeji, Adebayo, Adebayo, Philip, Akpalu, Josephine, Onyeonoro, Ugochukwu, Ogunmodede, James A, Akisanya, Cynthia, Mensah, Yaw, Oyinloye, Olalekan I, Appiah, Lambert, Agunloye, Atinuke M, Osaigbovo, Godwin O, Adeoye, Abiodun M, Adeleye, Osimhiarherhuo Ohifemen, Laryea, Ruth Y, Olunuga, Taiwo, Ogah, Okechukwu S, Oguike, Wisdom, Ogunronbi, Mayowa, Adeniyi, Wasiu, Olugbo, Obiabo Y, Bello, Abiodun H, Ogunjimi, Luqman, Diala, Samuel, Dambatta, Hamisu A, Singh, Arti, Adamu, Sheila, Obese, Vida, Adusei, Nathaniel, Owusu, Dorcas, Ampofo, Michael, Tagge, Raelle, Fawale, Bimbo, Yaria, Joseph, Akinyemi, Rufus O, and Owolabi, Mayowa O

Published
2023
Full Text
View/download PDF

6. Differential associations between pre-diabetes, diabetes and stroke occurrence among West Africans

Author

Sarfo, Fred Stephen, Ovbiagele, Bruce, Akinyemi, Joshua, Akpa, Onoja, Akpalu, Albert, Wahab, Kolawole, Ogbole, Godwin, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Osaigbovo, Godwin, Jenkins, Carolyn, Fakunle, Adekunle, Adeoye, Abiodun, Lackland, Dan, Arnett, Donna, Tiwari, Hemant K., Olunuga, Taiwo, Uvere, Ezinne, Fawale, Bimbo, Ogah, Okechukwu, Agunloye, Atinuke, Faniyan, Moyinoluwalogo, Diala, Samuel, Yinka, Oladele, Laryea, Ruth, Osimhiarherhuo, Adeleye, Akinsanya, Cynthia, Abdulwasiu, Adeniyi, Akpalu, Josephine, Arulogun, Oyedunni, Appiah, Lambert, Dambatta, Hamisu, Olayemi, Balogun, Onasanya, Akinola, Isah, Sulaiman, Akinyemi, Rufus, and Owolabi, Mayowa

Published
2022
Full Text
View/download PDF

8. Priorities to reduce the burden of hypertension in Africa through ACHIEVE

Author

Olowoyo, Paul, primary, Barango, Prebo, additional, Moran, Andrew, additional, Williams, Bryan, additional, Whelton, Paul K, additional, Owolabi, Mayowa, additional, Olowoyo, Paul, additional, Dzudie, Anastase, additional, Okekunle, Akinkunmi Paul, additional, Obiako, Reginald, additional, Mocumbi, Ana, additional, Beheiry, Hind, additional, Parati, Gianfranco, additional, Lackland, Daniel T., additional, Sarfo, Fred S., additional, Odili, Augustine, additional, Agyemang, Charles, additional, Campbell, Norman, additional, Kengne, Andre Pascal, additional, Pellicori, Pierpaolo, additional, Ebenezer, Ad Adams, additional, Adebayo, Oladimeji, additional, Olalusi, Oladotun, additional, Uvere, Ezinne, additional, Guzik, Tomasz J., additional, Kokuro, Collins, additional, Bukachi, Fred, additional, Osi, Kufor, additional, Ogah, Okechukwu S., additional, Delles, Christian, additional, Maffia, Pasquale, additional, Akinyemi, Rufus, additional, Ojji, Dike, additional, and Whelton, Paul K., additional

Published
2024
Full Text
View/download PDF

9. A Novel Afrocentric Stroke Risk Assessment Score: Models from the Siren Study

Author

Akpa, Onoja, Sarfo, Fred S., Owolabi, Mayowa, Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Osaigbovo, Godwin O., Ogbole, Godwin, Tiwari, Hemant K., Jenkins, Carolyn, Fakunle, Adekunle G., Olowookere, Samuel, Uvere, Ezinne O., Akinyemi, Joshua, Arulogun, Oyedunni, Akpalu, Josephine, Tito-Ilori, Moyinoluwalogo M., Asowata, Osahon J., Ibinaiye, Philip, Akisanya, Cynthia, Oyinloye, Olalekan I., Appiah, Lambert, Sunmonu, Taofik, Olowoyo, Paul, Agunloye, Atinuke M., Adeoye, Abiodun M., Yaria, Joseph, Lackland, Daniel T., Arnett, Donna, Laryea, Ruth Y., Adigun, Taiwo O., Okekunle, Akinkunmi P., Calys-Tagoe, Benedict, Ogah, Okechukwu S., Ogunronbi, Mayowa, Obiabo, Olugbo Y., Isah, Suleiman Y., Dambatta, Hamisu A., Tagge, Raelle, Ogenyi, Obande, Fawale, Bimbo, Melikam, Chimdinma L., Onasanya, Akinola, Adeniyi, Sunday, Akinyemi, Rufus, and Ovbiagele, Bruce

Published
2021
Full Text
View/download PDF

10. Frequency and factors associated with post-stroke seizures in a large multicenter study in West Africa

Author

Sarfo, Fred S., Akinyemi, Joshua, Akpalu, Albert, Wahab, Kolawole, Yaria, Joseph, Adebayo, Oladimeji, Komolafe, Morenike, Obiako, Reginald, Owolabi, Lukman, Osaigbovo, Godwin O., Jenkins, Carolyn, Mensah, Yaw, Ogbole, Godwin, Calys-Tagoe, Benedict, Adebayo, Philip, Appiah, Lambert, Singh, Arti, Fakunle, Adekunle, Uvere, Ezinne, Hemant, Tiwari, Balogun, Olayemi, Adeleye, Osi, Fawale, Bimbo, Abdulwasiu, Adeniyi, Ogunjimi, Luqman, Akinola, Onasanya, Arulogun, Oyedunni, Donna, Arnette, Ogah, Okechukwu, Akinyemi, Rufus, Ovbiagele, Bruce, and Owolabi, Mayowa O.

Published
2021
Full Text
View/download PDF

11. The Use of Qualitative Methods in Developing Implementation Strategies in Prevention Research for Stroke Survivors in Nigeria

Author

Hurst, Samantha, Arulogun, Oyedunni, Owolabi, Mayowa O, Akinyemi, Rufus O, Uvere, Ezinne, Warth, Stephanie, Fakunle, Gregory, and Ovbiagele, Bruce

Subjects
Medical Biochemistry and Metabolomics, Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Clinical Research, Prevention, Stroke, HIV/AIDS, Behavioral and Social Science, Rehabilitation, Health Services, 8.1 Organisation and delivery of services, Management of diseases and conditions, 7.3 Management and decision making, 7.1 Individual care needs, Health and social care services research, Good Health and Well Being, Caregivers, Disease Management, Focus Groups, Humans, Nigeria, Program Development, Qualitative Research, Survivors, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences, Medical biochemistry and metabolomics
Abstract

Implementing complex clinical interventions is a key challenge in many global regions. Local communities play a necessary role in enhancing feasibility and strengthening adaptive issues in the design and implementation of stroke interventions in developing countries. Drawing on the knowledge of physicians, patients, and caregivers, the authors employed qualitative methods as a phase 1 strategy to explore the challenges of stroke management and improve the adaptability and efficient delivery of a multimodal preventive intervention for secondary stroke disease in Nigeria. A total of 22 individual interviews were conducted with healthcare professionals, as well as 12 focus groups with patients and caregivers. Findings revealed four operational domains to improve strategies for phase 2 implementation and intervention: (1) barriers influencing optimal adherence in stroke survivors, (2) patient health beliefs and perceptions of patient health beliefs by others, (3) adoption of the "patient report card," and (4) "medical action plan" and family management strategies.

Published
2016

12. Non-cigarette Tobacco Use and Stroke Among West Africans: Evidence From the SIREN Study.

Author

Fakunle, Adekunle Gregory, Okekunle, Akinkunmi Paul, Asowata, Osahon Jeffery, Akpa, Onoja, Sarfo, Fred S, Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Osaigbovo, Godwin O, Adeoye, Abiodun M, Tiwari, Hemant K, Uvere, Ezinne O, Akinyemi, Joshua, Jenkins, Carolyn, Arulogun, Oyedunni, Ibinaiye, Philip, Appiah, Lambert T, and Bello, Temilade

Subjects
TOBACCO use, MAGNETIC resonance imaging, COMPUTED tomography, SYMPTOMS, STROKE
Abstract

Introduction Non-cigarette tobacco (NCT) represents a form of tobacco use with a misperceived significance in chronic disease events. Whether NCT use is sufficient to promote stroke events, especially among Africans, is yet to be understood. This study assessed the relationship between NCT use and stroke among indigenous Africans. Methods A total of 7617 respondents (NCT users: 41 vs. non-NCT: 7576) from the Stroke Investigative Research and Educational Network (SIREN) study were included in the current analysis. NCT use was defined as self-reported use of smoked (cigars or piper) or smokeless (snuff or chewed) tobacco in the past year preceding stroke events. Stroke was defined based on clinical presentation and confirmed with a cranial computed tomography/magnetic resonance imaging. Multivariable-adjusted logistic regression was applied to estimate the odds ratio (OR) and 95% confidence interval (CI) for the relationship of NCT with stroke at a two-sided p <.05. Results Out of the 41 (0.54%) who reported NCT use, 27 (65.9%) reported using smokeless NCT. NCT users were older than non-NCT users (62.8 ± 15.7 vs. 57.7 ± 14.8 years). Overall, NCT use was associated with first-ever stroke (OR: 2.08; 95% CI: 1.02, 4.23) in the entire sample. Notably, smokeless NCT use was independently associated with higher odds of stroke (OR: 2.74; 95% CI: 1.15, 6.54), but smoked NCT use (OR: 0.16; 95% CI: 0.02, 1.63) presented a statistically insignificant association after adjusting for hypertension and other covariates. Conclusions NCT use was associated with higher odds of stroke, and public health interventions targeting NCT use might be promising in reducing the burden of stroke among indigenous Africans. Implications A detailed understanding of the relationship between NCT use and stroke will likely inform well-articulated policy guidance and evidence-based recommendations for public health prevention and management of stroke on the African continent. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

13. Clinical and neuroimaging factors associated with 30-day fatality among indigenous West Africans with spontaneous intracerebral hemorrhage

Author

Komolafe, Morenikeji A., primary, Sunmonu, Taofiki, additional, Akinyemi, Joshua, additional, Sarfo, Fred S., additional, Akpalu, Albert, additional, Wahab, Kolawole, additional, Obiako, Reginald, additional, Owolabi, Lukman, additional, Osaigbovo, Godwin O., additional, Ogbole, Godwin, additional, Tiwari, Hemant K., additional, Jenkins, Carolyn, additional, Lackland, Daniel T., additional, Fakunle, Adekunle G., additional, Uvere, Ezinne, additional, Akpa, Onoja, additional, Dambatta, Hamisu A., additional, Akpalu, Josephine, additional, Onasanya, Akinola, additional, Olaleye, Adeniji, additional, Ogah, Okechukwu S., additional, Isah, Sulaiman Y., additional, Fawale, Micheal B., additional, Adebowale, Akintunde, additional, Okekunle, Akinkunmi P., additional, Arnett, Donna, additional, Adeoye, Abiodun M., additional, Agunloye, Atinuke M., additional, Bello, Abiodun H., additional, Aderibigbe, Adeniyi S., additional, Idowu, Ahmed O., additional, Sanusi, Ahmad A., additional, Ogunmodede, Adebimpe, additional, Balogun, Simon A., additional, Egberongbe, Adedeji A., additional, Rotimi, Folorunso T., additional, Fredrick, Adeyemi, additional, Akinnuoye, Andrew O., additional, Adeniyi, Folu A., additional, Calys-Tagoe, Benedict, additional, Adebayo, Philip, additional, Arulogun, Oyedunni, additional, Agbogu-Ike, Obiageli U., additional, Yaria, Joseph, additional, Appiah, Lambert, additional, Ibinaiye, Philip, additional, Singh, Arti, additional, Adeniyi, Sunday, additional, Olalusi, Oladotun, additional, Mande, Aliyu, additional, Balogun, Olayemi, additional, Akinyemi, Rufus, additional, Ovbiagele, Bruce, additional, and Owolabi, Mayowa, additional

Published
2023
Full Text
View/download PDF

14. Non-cigarette Tobacco Use and Stroke Among West Africans: Evidence From the SIREN Study

Author

Fakunle, Adekunle Gregory, primary, Okekunle, Akinkunmi Paul, additional, Asowata, Osahon Jeffery, additional, Akpa, Onoja, additional, Sarfo, Fred S, additional, Akpalu, Albert, additional, Wahab, Kolawole, additional, Obiako, Reginald, additional, Komolafe, Morenikeji, additional, Owolabi, Lukman, additional, Osaigbovo, Godwin O, additional, Adeoye, Abiodun M, additional, Tiwari, Hemant K, additional, Uvere, Ezinne O, additional, Akinyemi, Joshua, additional, Jenkins, Carolyn, additional, Arulogun, Oyedunni, additional, Ibinaiye, Philip, additional, Appiah, Lambert T, additional, Bello, Temilade, additional, Singh, Arti, additional, Yaria, Joseph, additional, Calys-Tagoe, Benedict, additional, Ogbole, Godwin, additional, Chukwuonye, Ijezie, additional, Melikam, Chidinma, additional, Adebayo, Philip, additional, Mensah, Yaw, additional, Adebayo, Oladimeji, additional, Adeniyi, Sunday, additional, Oguike, Wisdom, additional, Donna, Arnett, additional, Akinyemi, Rufus, additional, Ovbiagele, Bruce, additional, and Owolabi, Mayowa, additional

Published
2023
Full Text
View/download PDF

15. Research participants’ perception of ethical issues in stroke genomics and neurobiobanking research in Africa

Author

Jegede, Ayodele, primary, Balogun, Olubukola, additional, Olorunsogbon, Olorunyomi Felix, additional, Nichols, Michelle, additional, Akinyemi, Joshua, additional, Jenkins, Carolyn, additional, Ogunronbi, Mayowa, additional, Singh, Arti, additional, Obiako, Reginald, additional, Wahab, Kolawole, additional, Bello, Abiodun, additional, Akpalu, Albert, additional, Sarfo, Fred S., additional, Owolabi, Lukman F., additional, Ojebuyi, Babatunde, additional, Adigun, Muyiwa, additional, Olujobi, Dorcas, additional, Musbahu, Rabiu, additional, Titiloye, Musibau, additional, Afolami, Ibukun, additional, Calys-Tagoe, Benedict, additional, Uvere, Ezinne, additional, Laryea, Ruth, additional, Fakunle, Adekunle, additional, Adeleye, Osi, additional, Adesina, Deborah, additional, Mensah, Nathaniel, additional, Oguike, Wisdom, additional, Coleman, Nathaniel, additional, Adeniyi, Sunday, additional, Omotoso, Lanre, additional, Asibey, Shadrack, additional, Melikam, Lois, additional, Yusuf, Jibril, additional, Gbenga, Abdullateef, additional, Mande, Aliyu, additional, Uthman, Muhammed, additional, Kalaria, Rajesh N., additional, Owolabi, Mayowa, additional, Ovbiagele, Bruce, additional, Arulogun, Oyedunni, additional, and Akinyemi, Rufus O., additional

Published
2023
Full Text
View/download PDF

16. Risk Factor Characterization of Ischemic Stroke Subtypes Among West Africans

Author

Sarfo, Fred S., Ovbiagele, Bruce, Akpa, Onoja, Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Ogbole, Godwin, Calys-Tagoe, Benedict, Fakunle, Adekunle, Sanni, Taofeek, Mulugeta, Gebregziabher, Abdul, Salaam, Akintunde, Adeseye A., Olowookere, Samuel, Uvere, Ezinne O., Ibinaiye, Philip, Akinyemi, Joshua, Uwanuruochi, Kelechukwu, Olayemi, Balogun, Odunlami, Olufemi A., Abunimye, Esther, Arulogun, Oyedunni, Isah, Suleiman Y., Abubakar, Sani A., Oladimeji, Adebayo, Adebayo, Philip, Shidali, Vincent, Chukwuonye, Innocent I., Akpalu, Josephine, Tito-Ilori, Moyinoluwalogo M., Asowata, Osahon J., Sanya, Emmanuel O., Amusa, Ganiyu, Onyeonoro, Ugochukwu, Ogunmodede, James A., Sule, Abdullateef G., Akisanya, Cynthia, Mensah, Yaw, Oyinloye, Olalekan I., Appiah, Lambert, Agunloye, Atinuke M., Osaigbovo, Godwin O., Olabinri, Eunice, Kolo, Philip M., Okeke, Obiora, Adeoye, Abiodun M., Ajose, Olabamiji, Jenkins, Carolyn, Lackland, Daniel T., Egberongbe, Adedeji A., Adeniji, Olaleye, Ohifemen Adeleye, Osimhiarherhuo, Tiwari, Hemant K., Arnett, Donna, Laryea, Ruth Y., Olunuga, Taiwo, Akinwande, Kazeem S., Imoh, Lucius, Ogah, Okechukwu S., Melikam, Ezinne S., Adebolaji, Adeyemo, Oguike, Wisdom, Ogunronbi, Olumayowa, Adeniyi, Wasiu, Olugbo, Obiabo Y., Bello, Abiodun H., Ohagwu, Kenneth A., Ogunjimi, Luqman, Agyekum, Francis, Iheonye, Henry, Adesina, Julius, Diala, Samuel, Dambatta, Hamisu A., Ikubor, Joyce, Singh, Arti, Adamu, Sheila, Obese, Vida, Adusei, Nathaniel, Owusu, Dorcas, Ampofo, Michael, Tagge, Raelle, Efidi, Richard, Fawale, Bimbo, Yaria, Joseph, Akinyemi, Rufus, and Owolabi, Mayowa

Published
2021
Full Text
View/download PDF

17. Cost and cost-effectiveness analysis of a bundled intervention to enhance outcomes after stroke in Nigeria: Rationale and design

Author

Olaniyan, Olanrewaju, Owolabi, Mayowa O, Akinyemi, Rufus O, Salako, Babatunde L, Hurst, Samantha, Arulogun, Oyedunni, Gebregziabher, Mulugeta, Uvere, Ezinne, and Ovbiagele, Bruce

Subjects
Health Services and Systems, Health Sciences, Health Services, Clinical Research, Stroke, Brain Disorders, Comparative Effectiveness Research, Cost Effectiveness Research, Health and social care services research, 8.2 Health and welfare economics, 8.1 Organisation and delivery of services, Good Health and Well Being, Cost-effectiveness, Costs and cost analysis, Nigeria
Abstract

The economic and social costs of stroke to the society can be enormous. These costs can cause serious economic damage to both the individual and the nation. It is thus important to conduct a cost effectiveness analysis to indicate whether an intervention provides high value where its health benefits justify its costs. This study will provide evidence based on the costs of stroke with a view of improving intervention and treatments of stoke survivors in Nigeria. This study utilizes two types of economic evaluation methods - cost-effectiveness analysis and cost-benefit analysis - to determine the economic impact of Tailored Hospital-based Risk Reduction to Impede Vascular Events after Stroke (THRIVES) intervention. The study is conducted in four Nigerian hospitals where 400 patients are recruited to participate in the study. The cost-effectiveness of THRIVES post-discharge intervention is compared with the control Intervention scenario, which is the usual and customary care delivered at each health facility in terms of cost per quality adjusted life years (QALYs). It is expected that successful implementation of the project would serve as a model of cost-effective quality stroke care for implementation.

Published
2015

18. Factors associated with frequency of fruit and vegetable consumption among selected sub-Saharan African populations: evidence from the Cardiovascular H3Africa Innovation Resource Project.

Author

Okekunle, Akinkunmi Paul, Asowata, Osahon Jeffery, Akpa, Onoja Matthew, Fakunle, Adekunle Gregory, Chikowore, Tinashe, Mohamed, Shukri F, Obiako, Reginald, Komolafe, Morenikeji, Osaigbovo, Godwin O, Ogbole, Godwin, Arulogun, Oyedunni, Sarfo, Fred Stephen, Wahab, Kolawole, Owolabi, Lukman, Akinyemi, Joshua, Akpalu, Albert, Uvere, Ezinne, Akinyemi, Rufus, Jenkins, Carolyn, and Arnett, Donna K

Subjects
SUB-Saharan Africans, VEGETABLES, FRUIT, DISEASE risk factors, FAMILY history (Medicine)
Abstract

Background Frequent fruit and vegetable consumption is considered a promising dietary behaviour that protects health. However, most existing studies about the factors associated with this phenomenon among Africans are based on single-country reports, apart from one meta-regression combining smaller studies. This study harmonized large datasets and assessed factors associated with the frequency of fruit and vegetable consumption in this population. Methods Individual-level data on sociodemographics, lifestyle and diet from 20 443 participants across five African countries (Burkina Faso, Ghana, Kenya, South Africa and Nigeria), from the Stroke Investigative Research and Educational Network (SIREN) and Africa Wits-INDEPTH partnership for Genomic Research (AWI-Gen) studies, were harmonized. Total frequency of fruit and vegetable consumption (in portions/week) was classified as 'low' (≤6), 'moderate' (7–14) and 'high' (≥15). Adjusted odds ratios (aORs) and 95% confidence intervals (CIs) of factors associated with the total frequency of fruit and vegetable consumption (using 'low' consumption as the reference) were estimated using multinomial regression models. Results Mean age of participants was 54.3 ± 11.8 years, 10 641 (52.1%) were female, and the median (interquartile range) frequency of total fruit and vegetable consumption was 10.0 (4.0, 21.0) portions/week. Participants with a family history of cardiovascular disease [moderate (aOR, 0.92; 95% CI, 0.85, 1.00) and high (aOR, 0.85; 95% CI, 0.78, 0.92)], current smokers [moderate (aOR, 0.83; 95% CI, 0.74, 0.94) and high (aOR, 0.78; 95% CI, 0.69, 0.88)], current alcohol users [moderate (aOR, 0.92; 95% CI, 0.85, 1.00) and high (aOR, 0.82; 95% CI, 0.76, 0.89)] and physically inactive participants [moderate (aOR, 0.85; 95% CI, 0.75, 0.96) and high (aOR, 0.80; 95% CI, 0.70, 0.90)] were less likely to consume fruits and vegetables frequently. Conclusion Africans with lifestyle risk factors for cardiovascular disease were less likely to consume fruit and vegetables frequently. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

20. Dominant modifiable risk factors for stroke in Ghana and Nigeria (SIREN): a case-control study

Author

Owolabi, Mayowa Ojo, Sarfo, Fred Stephen, Akinyemi, Rufus, Gebregziabher, Mulugeta, Akpa, Onoja, Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Owolabi, Lukman, Ovbiagele, Bruce, Tiwari, Hemant K, Arnett, Donna, Lackland, Daniel, Adeoye, Abiodun Moshood, Akin, Ojagbemi, Ogbole, Godwin, Jenkins, Carolyn, Arulogun, Oyedunni, Ryan, Irvin Marguerite, Armstrong, Kevin, Olowoyo, Paul, Komolafe, Morenikeji, Osaigbovo, Godwin, Obiabo, Olugbo, Chukwuonye, Innocent, Adebayo, Philip, Adebayo, Oladimeji, Omololu, Ayanfe, Otubogun, Folajimi, Olaleye, Adeniji, Durodola, Amina, Olunuga, Taiwo, Akinwande, Kazeem, Aridegbe, Mayowa, Fawale, Bimbo, Adeleye, Omisore, Kolo, Philip, Appiah, Lambert, Singh, Arti, Adamu, Sheila, Awuah, Dominic, Saulson, Raelle, Agyekum, Francis, Shidali, Vincent, Ogah, Okechukwu, Oguntade, Ayodipopo, Umanruochi, Kelechi, Iheonye, Henry, Imoh, Lucius, Afolaranmi, Tolulope, Calys-Tagoe, Benedict, Okeke, Obiora, Fakunle, Adekunle, Akinyemi, Joshua, Akpalu, Josephine, Ibinaiye, Philip, Agunloye, Atinuke, Sanni, Taofeeq, Bisi, Ayotunde, Efidi, Chika, Bock-Oruma, Andrew, Melikam, Sylvia, Olaniyan, Lanre, Yaria, Joseph, Odo, Chidi Joseph, Lakoh, Sulaiman, Ogunjimi, Luqman, Salaam, Abdul, Oyinloye, Lekan, Asaleye, Caroline, Sanya, Emmanuel, Olowookere, Samuel, Makanjuola, Akintomiwa, Oguntoye, Ayobami, Uvere, Ezinne, Faniyan, Moyinoluwalogo, Akintunde, Adeseye, Kehinde, Issa, Diala, Samuel, Adeleye, Osimhiarherhuo, Ajose, Olabanji A., Onyeonoro, Ugochukwu, Amusa, Adeniyi G., Owusu, Dorcas, Mensah, Yaw, Owolabi, Mayowa O, and Sarfo, Fred

Published
2018
Full Text
View/download PDF

22. Capacity-Building for Stroke Genomic Research Data Collection: The African Neurobiobank Ethical, Legal, and Social Implications Project Experience

Author

Uvere, Ezinne O., primary, Nichols, Michelle, additional, Ojebuyi, Babatunde R., additional, Isah, Suleiman Yahaya, additional, Calys-Tagoe, Benedict, additional, Jenkins, Carolyn, additional, Obiako, Reginald, additional, Owolabi, Lukman, additional, Akpalu, Albert, additional, Sarfo, Fred Stephen, additional, Ogunronbi, Olumayowa, additional, Adigun, Muyiwa, additional, Fakunle, Gregory Adekunle, additional, Hamzat, Bello, additional, Laryea, Ruth, additional, Uthman, Babatunde, additional, Akinyemi, Joshua O., additional, Adeleye, Osi, additional, Melikam, Lois, additional, Balogun, Olubukola, additional, Sule, Abdullateef, additional, Adeniyi, Sunday, additional, Asibey, Shadrack O., additional, Oguike, Wisdom, additional, Olorunsogbon, Olorunyomi, additional, Singh, Arti, additional, Titiloye, Musibau A., additional, Musbahu, Rabiu, additional, Wahab, Kolawole W., additional, Kalaria, Rajesh N., additional, Jegede, Ayodele S., additional, Owolabi, Mayowa O., additional, Ovbiagele, Bruce, additional, Arulogun, Oyedunni S., additional, and Akinyemi, Rufus O., additional

Published
2023
Full Text
View/download PDF

26. Carotid and Vertebral Atherosclerosis in West African Stroke Patients: Findings from the Stroke Investigative Research and Education Network

Author

Aridegbe, Mayowa, Fawale, Michael, Olowookere, Samuel, Imoh, Lucius, Adeleye, Osi, Efidi, Richard, Tiwari, Hemant, Mensah, Yaw, Calys-Tagoe, Benedict, Akintunde, Adeseye, Ogunjimi, Luqman, Olugbo, Obiabo, Egberongbe, Adedeji, Abdullahi, Muhammad, Sumonu, Taofiki, Sanni, Taofeek, Ogah, Okechukwu, Adeoye, Abiodun, Uvere, Ezinne, Ibinaiye, Philip, Akinyemi, Rufus, Ovbiagele, Bruce, Owolabi, Mayowa, Osaigbovo, Godwin, Ogbole, Godwin, Agunloye, Atinuke, Akinyemi, Joshua, Akpalu, Albert, Sarfo, Fred, Akpa, Onoja, Gebregziabher, Mulugeta, Arulogun, Oyedunni, Komolafe, Morenikeji, Wahab, Kolawole, Jenkins, Carolyn, Omisore, Adeleye, Obiako, Reginald, Owolab, Luqman, Fakunle, Adekunle, Ikubor, Joyce, Salaam, Abdul, Famurewa, Olusola, Adebayo, Oladimeji, Asaleye, Christianah, Akisanya, Cynthia, and Olabinri, Eunice

Subjects
Stroke, Carotid, Vertebral, Atherosclerosis, West Africa
Abstract

Background: We evaluated the characteristics of carotid and vertebral atherosclerosis in indigenous West Africans with stroke. Methodology: Of the 3778 stroke patients recruited between 01/2014 and 08/2017, 1070 (28.3%) received carotid and vertebral artery evaluation with B-mode Ultrasound. Carotid and vertebral intima-media thickness (IMT) using multiple site technique were measured bilaterally and plaque frequency was determined. Descriptive and comparative analyses between stroke types and vessels were carried out. Results: There were 809 (75.6%) patients with ischemic stroke. The prevalence of intima-media thickening in the study population was 84.0% (898/1070) [95% CI: 81.7-86.1], being higher in the ischemic stroke (688/809, 85.0%) [95% CI: 82.4-87.3] than in the hemorrhagic stroke group (211/261, 80.8%) [95% CI: 75.6-85.2]. Overall prevalence of plaques which was 26.1% [95% CI: 23.5-28.8], was found also to be higher in ischemic than hemorrhagic stroke (29.8% [95% CI: 26.7-33.0] vs. 14.6% [95% CI: 10.8-19.4], p < 0.05). The mean IMT (carotids: 2.01+1.33 mm; vertebrals: 0.96+0.54mm, p < 0.001) and prevalence of plaques (carotids: 8.8%; vertebrals: 1.7%, p < 0.001) were higher in carotid than vertebral arteries. Age, hypertension, level of formal education, history of smoking, average monthly income, and family histories of hypertension and stroke were associated with intima-media thickening in the carotids (all p < 0.05) in the ischemic stroke patients while family history of hypertension, diabetes mellitus, and level of formal education were independently associated with intima-media thickening in the carotids (all p < 0.05) in the hemorrhagic stroke patients. No CVRF showed an independent association with the presence of plaque in the carotid and vertebral arteries both stroke types. Conclusions: One of four stroke patients in our cohort had atherosclerotic plaques, with ischemic patients being twice as likely to have this burden compared to hemorrhagic patients, and carotid atherosclerosis being five times as frequent as vertebral atherosclerosis. &nbsp

Published
2023

27. Secondhand smoke exposure is independently associated with stroke among non-smoking adults in West Africa

Author

Okekunle, Akinkunmi Paul, primary, Asowata, Osahon Jeffery, additional, Fakunle, Adekunle G., additional, Akpa, Onoja Matthew, additional, Sarfo, Fred S., additional, Akpalu, Albert, additional, Wahab, Kolawole, additional, Obiako, Reginald, additional, Komolafe, Morenikeji, additional, Owolabi, Lukman, additional, Osaigbovo, Godwin O., additional, Tiwari, Hemant K., additional, Akinyemi, Joshua, additional, Jenkins, Carolyn, additional, Arulogun, Oyedunni, additional, Ibinaiye, Philip, additional, Appiah, Lambert, additional, Agunloye, Atinuke M., additional, Adeoye, Abiodun M., additional, Yaria, Joseph, additional, Calys-Tagoe, Benedict, additional, Uvere, Ezinne O., additional, Ogbole, Godwin, additional, Agyekum, Francis, additional, Sanni, Taofeek A., additional, Amusa, Ganiyu A., additional, Ogunronbi, Mayowa, additional, Olowookere, Samuel, additional, Balogun, Olayemi, additional, Ogunmodede, James A., additional, Olalusi, Oladotun V., additional, Samuel, Diala, additional, Mande, Aliyu, additional, Rabiu, Musbahu, additional, Adebayo, Philip, additional, Sunday, Adeniyi, additional, Imoh, Lucius Chidiebere, additional, Oguntade, Ayodipupo S., additional, Ajose, Abiodun, additional, Singh, Arti, additional, Adeegbe, Oluwayemisi T., additional, Mensah, Yaw, additional, Fawale, Michael B., additional, Abdul, Salaam, additional, Ikubor, Joyce, additional, Tolulope, Afolaranmi, additional, Yahaya, Isah S., additional, Akisanya, Cynthia, additional, Odo, Chidi J., additional, Efidi, Richard, additional, Chukwuonye, Innocent I., additional, Shidali, Vincent, additional, Adebowale, Akintunde, additional, Ohagwu, Kenneth A., additional, Adeleye, Osimhiarherhuo O., additional, Iheonye, Henry, additional, Akintunde, Adeseye, additional, Olabinri, Eunice, additional, Akpalu, Josephine, additional, Adesina, Julius, additional, Onyeonoro, Ugochukwu, additional, Onasanya, Akinola, additional, Arnett, Donna K., additional, Lackland, Daniel, additional, Akinyemi, Rufus, additional, Ovbiagele, Bruce, additional, and Owolabi, Mayowa, additional

Published
2022
Full Text
View/download PDF

28. COMMUNICATING ELSI ISSUES IN NEUROBIOBANKING AND STROKE GENOMIC RESEARCH IN AFRICA: PROJECT INTERVENTION TOOLS DEVELOPMENT AND EVALUATION PROCEDURES

Author

Ojebuyi, Babatunde R., Afolami, Ibukun, Adigun, Muyiwa, Singh, Arti, Jenkins, Carolyn, Nichols, Michelle, Wahab, Kolawole, Bello, Abiodun, Sarfo, Fred S., Owolabi, Lukman F., Musbahu, Rabiu, Obiako, Reginald, Akpalu, Albert, Ogunronbi, Mayowa, Olorunsogbon, Olorunyomi, Calys-Tagoe, Benedict, Adesina, Deborah, Coleman, Nathaniel, Sule, Abdullateef G., Mande, Aliyu, Uthman, Muhammed, Titiloye, Musibau, Uvere, Ezinne, Bukola, Odunola, Melikam, Sylvia, Laryea, Ruth, Fakunle, Adekunle, Adeleye, Osi, Mensah, Nathaniel, Yusuf, Jibril, Adeniyi, Sunday, Asibey, Shadrack, Omotoso, Lanre, Melikam, Lois, Olujobi, Dorcas, Oguike, Wisdom, Akinyemi, Joshua, Jegede, Ayodele, Kalaria, Rajesh, Ovbiagele, Bruce, Owolabi, Mayowa, Arulogun, Oyedunni, and Akinyemi, Rufus

Published
2023
Full Text
View/download PDF

30. Frequent vegetable consumption is inversely associated with hypertension among indigenous Africans

Author

Akpa, Onoja Matthew, primary, Okekunle, Akinkunmi Paul, additional, Asowata, Osahon Jeffery, additional, Chikowore, Tinashe, additional, Mohamed, Shukri F, additional, Sarfo, Fred, additional, Akinyemi, Rufus, additional, Akpalu, Albert, additional, Wahab, Kolawole, additional, Obiako, Reginald, additional, Komolafe, Morenikeji, additional, Owolabi, Lukman, additional, Osaigbovo, Godwin O, additional, Ogbole, Godwin, additional, Tiwari, Hemant K, additional, Akinyemi, Joshua, additional, Fakunle, Adekunle, additional, Uvere, Ezinne, additional, Adeoye, Abiodun M, additional, Lackland, Daniel, additional, Arnett, Donna K, additional, Ovbiagele, Bruce, additional, Ramsay, Michèle, additional, and Owolabi, Mayowa, additional

Published
2022
Full Text
View/download PDF

31. Abstract P069: Vegetable Consumption And Hypertension Among 16,445 Africans

Author

Okekunle, Akinkunmi, primary, Akpa, Onoja, additional, Asowata, Osahon, additional, Chikowore, Tinashe, additional, Mohamed, Shukri, additional, SARFO, FRED S, additional, Akinyemi, Rufus O, additional, Akpalu, Albert, additional, Wahab, Kolawole, additional, Obiako, Reginald, additional, Komolafe, Morenikeji, additional, Owolabi, Lukman, additional, Osaigbovo, Godwin, additional, Ogbole, Godwin, additional, Tiwari, Hemant K, additional, Akinyemi, Joshua, additional, Fakunle, Adekunle, additional, Uvere, Ezinne, additional, Adeoye, Abiodun, additional, Lackland, Daniel T, additional, Arnett, Donna K, additional, Ovbiagele, Bruce, additional, Ramsay, Michèle, additional, and Owolabi, Mayowa, additional

Published
2022
Full Text
View/download PDF

32. Stroke genetics informs drug discovery and risk prediction across ancestries

Author

Mishra, Aniket, Malik, Rainer, Hachiya, Tsuyoshi, Jurgenson, Tuuli, Namba, Shinichi, Posner, Daniel C, Kamanu, Frederick K, Koido, Masaru, Le Grand, Quentin, Shi, Mingyang, He, Yunye, Georgakis, Marios K, Caro, Ilana, Krebs, Kristi, Liaw, Yi-Ching, Vaura, Felix C, Lin, Kuang, Winsvold, Bendik Slagsvold, Srinivasasainagendra, Vinodh, Parodi, Livia, Bae, Hee-Joon, Chauhan, Ganesh, Chong, Michael R, Tomppo, Liisa, Akinyemi, Rufus, Roshchupkin, Gennady V, Habib, Naomi, Jee, Yon Ho, Thomassen, Jesper Qvist, Abedi, Vida, Carcel-Marquez, Jara, Nygaard, Marianne, Leonard, Hampton L, Yang, Chaojie, Yonova-Doing, Ekaterina, Knol, Maria J, Lewis, Adam J, Judy, Renae L, Ago, Tetsuro, Amouyel, Philippe, Armstrong, Nicole D, Bakker, Mark K, Bartz, Traci M, Bennett, David A, Bis, Joshua C, Bordes, Constance, Borte, Sigrid, Cain, Anael, Ridker, Paul M, Cho, Kelly, Chen, Zhengming, Cruchaga, Carlos, Cole, John W, de Jager, Phil L, de Cid, Rafael, Endres, Matthias, Ferreira, Leslie E, Geerlings, Mirjam I, Gasca, Natalie C, Gudnason, Vilmundur, Hata, Jun, He, Jing, Heath, Alicia K, Ho, Yuk-Lam, Havulinna, Aki S, Hopewell, Jemma C, Hyacinth, Hyacinth I, Inouye, Michael, Jacob, Mina A, Jeon, Christina E, Jern, Christina, Kamouchi, Masahiro, Keene, Keith L, Kitazono, Takanari, Kittner, Steven J, Konuma, Takahiro, Kumar, Amit, Lacaze, Paul, Launer, Lenore J, Lee, Keon-Joo, Lepik, Kaido, Li, Jiang, Li, Liming, Manichaikul, Ani, Markus, Hugh S, Marston, Nicholas A, Meitinger, Thomas, Mitchell, Braxton D, Montellano, Felipe A, Morisaki, Takayuki, Mosley, Thomas H, Nalls, Mike A, Nordestgaard, Borge G, O'Donnell, Martin J, Okada, Yukinori, Onland-Moret, N Charlotte, Ovbiagele, Bruce, Peters, Annette, Psaty, Bruce M, Rich, Stephen S, Rosand, Jonathan, Sabatine, Marc S, Sacco, Ralph L, Saleheen, Danish, Sandset, Else Charlotte, Salomaa, Veikko, Sargurupremraj, Muralidharan, Sasaki, Makoto, Satizabal, Claudia L, Schmidt, Carsten O, Shimizu, Atsushi, Smith, Nicholas L, Sloane, Kelly L, Sutoh, Yoichi, Sun, Yan V, Tanno, Kozo, Tiedt, Steffen, Tatlisumak, Turgut, Torres-Aguila, Nuria P, Tiwari, Hemant K, Tregouet, David-Alexandre, Trompet, Stella, Tuladhar, Anil Man, Tybjaerg-Hansen, Anne, van Vugt, Marion, Vibo, Riina, Verma, Shefali S, Wiggins, Kerri L, Wennberg, Patrik, Woo, Daniel, Wilson, Peter WF, Xu, Huichun, Yang, Qiong, Yoon, Kyungheon, Lee, Jin-Moo, Cheng, Yu-Ching, Meschia, James F, Chen, Wei Min, Sale, Michele M, Zonderman, Alan B, Evans, Michele K, Wilson, James G, Correa, Adolfo, Traylor, Matthew, Lewis, Cathryn M, Carty, Cara L, Reiner, Alexander, Haessler, Jeffrey, Langefeld, Carl D, Gottesman, Rebecca F, Yaffe, Kristine, Liu, Yong Mei, Kooperberg, Charles, Lange, Leslie A, Furie, Karen L, Arnett, Donna K, Benavente, Oscar R, Grewal, Raji P, Peddareddygari, Leema Reddy, Hveem, Kristian, Lindstrom, Sara, Wang, Lu, Smith, Erin N, Gordon, William, van Hylckama Vlieg, Astrid, de Andrade, Mariza, Brody, Jennifer A, Pattee, Jack W, Brumpton, Ben M, Suchon, Pierre, Chen, Ming-Huei, Frazer, Kelly A, Turman, Constance, Germain, Marine, MacDonald, James, Braekkan, Sigrid K, Armasu, Sebastian M, Pankratz, Nathan, Jackson, Rebecca D, Nielsen, Jonas B, Giulianini, Franco, Puurunen, Marja K, Ibrahim, Manal, Heckbert, Susan R, Bammler, Theo K, McCauley, Bryan M, Taylor, Kent D, Pankow, James S, Reiner, Alexander P, Gabrielsen, Maiken E, Deleuze, Jean-Francois, O'Donnell, Chris J, Kim, Jihye, McKnight, Barbara, Kraft, Peter, Hansen, John-Bjarne, Rosendaal, Frits R, Heit, John A, Tang, Weihong, Morange, Pierre-Emmanuel, Johnson, Andrew D, Kabrhel, Christopher, van Dijk, Ewoud J, Koudstaal, Peter J, Luijckx, Gert-Jan, Nederkoorn, Paul J, van Oostenbrugge, Robert J, Visser, Marieke C, Wermer, Marieke JH, Kappelle, L Jaap, Esko, Tonu, Metspalu, Andres, Magi, Reedik, Nelis, Mari, Irvin, Marguerite R, de Leeuw, Frank-Erik, Levi, Christopher R, Maguire, Jane, Jimenez-Conde, Jordi, Sharma, Pankaj, Sudlow, Cathie LM, Rannikmae, Kristiina, Schmidt, Reinhold, Slowik, Agnieszka, Pera, Joanna, Thijs, Vincent NS, Lindgren, Arne G, Ilinca, Andreea, Melander, Olle, Engstrom, Gunnar, Rexrode, Kathryn M, Rothwell, Peter M, Stanne, Tara M, Johnson, Julie A, Danesh, John, Butterworth, Adam S, Heitsch, Laura, Boncoraglio, Giorgio B, Kubo, Michiaki, Pezzini, Alessandro, Rolfs, Arndt, Giese, Anne-Katrin, Weir, David, Ross, Owen A, Lemmons, Robin, Soderholm, Martin, Cushman, Mary, Jood, Katarina, McDonough, Caitrin W, Bell, Steven, Linkohr, Birgit, Lee, Tsong-Hai, Putaala, Jukka, Anderson, Christopher D, Lopez, Oscar L, Jian, Xueqiu, Schminke, Ulf, Cullell, Natalia, Delgado, Pilar, Ibanez, Laura, Krupinski, Jerzy, Lioutas, Vasileios, Matsuda, Koichi, Montaner, Joan, Muino, Elena, Roquer, Jaume, Sarnowski, Chloe, Sattar, Naveed, Sibolt, Gerli, Teumer, Alexander, Rutten-Jacobs, Loes, Kanai, Masahiro, Gretarsdottir, Solveig, Rost, Natalia S, Yusuf, Salim, Almgren, Peter, Ay, Hakan, Bevan, Steve, Brown, Robert D, Carrera, Caty, Buring, Julie E, Chen, Wei-Min, Cotlarciuc, Ioana, de Bakker, Paul IW, DeStefano, Anita L, den Hoed, Marcel, Duan, Qing, Engelter, Stefan T, Falcone, Guido J, Gustafsson, Stefan, Hassan, Ahamad, Holliday, Elizabeth G, Howard, George, Hsu, Fang-Chi, Ingelsson, Erik, Harris, Tamara B, Kissela, Brett M, Kleindorfer, Dawn O, Langenberg, Claudia, Lemmens, Robin, Leys, Didier, Lin, Wei-Yu, Lorentzen, Erik, Magnusson, Patrik K, McArdle, Patrick F, Pulit, Sara L, Rice, Kenneth, Sakaue, Saori, Sapkota, Bishwa R, Tanislav, Christian, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Tzourio, Christophe, van Duijn, Cornelia M, Walters, Matthew, Wareham, Nicholas J, Amin, Najaf, Aparicio, Hugo J, Attia, John, Beiser, Alexa S, Berr, Claudine, Bustamante, Mariana, Caso, Valeria, Choi, Seung Hoan, Chowhan, Ayesha, Dartigues, Jean-Francois, Delavaran, Hossein, Dorr, Marcus, Ford, Ian, Gurpreet, Wander S, Hamsten, Anders, Hozawa, Atsushi, Ingelsson, Martin, Iwasaki, Motoki, Kaffashian, Sara, Kalra, Lalit, Kjartansson, Olafur, Kloss, Manja, Labovitz, Daniel L, Laurie, Cathy C, Li, Linxin, Lind, Lars, Lindgren, Cecilia M, Makoto, Hirata, Minegishi, Naoko, Morris, Andrew P, Muller-Nurasyid, Martina, Norrving, Bo, Ogishima, Soichi, Parati, Eugenio A, Pedersen, Nancy L, Perola, Markus, Jousilahti, Pekka, Pileggi, Silvana, Rabionet, Raquel, Riba-Llena, Iolanda, Ribases, Marta, Romero, Jose R, Rudd, Anthony G, Sarin, Antti-Pekka, Sarju, Ralhan, Satoh, Mamoru, Sawada, Norie, Sigurdsson, Asgeir, Smith, Albert, Stine, O Colin, Stott, David J, Strauch, Konstantin, Takai, Takako, Tanaka, Hideo, Touze, Emmanuel, Tsugane, Shoichiro, Uitterlinden, Andre G, Valdimarsson, Einar M, van der Lee, Sven J, Wakai, Kenji, Williams, Stephen R, Wolfe, Charles DA, Wong, Quenna, Yamaji, Taiki, Sanghera, Dharambir K, Stefansson, Kari, Martinez-Majander, Nicolas, Sobue, Kenji, Soriano-Tarraga, Carolina, Volzke, Henry, Akpa, Onoja, Sarfo, Fred S, Akpalu, Albert, Obiako, Reginald, Wahab, Kolawole, Osaigbovo, Godwin, Owolabi, Lukman, Komolafe, Morenikeji, Jenkins, Carolyn, Arulogun, Oyedunni, Ogbole, Godwin, Adeoye, Abiodun M, Akinyemi, Joshua, Agunloye, Atinuke, Fakunle, Adekunle G, Uvere, Ezinne, Olalere, Abimbola, Adebajo, Olayinka J, Chen, Junshi, Clarke, Robert, Collins, Rory, Guo, Yu, Wang, Chen, Lv, Jun, Peto, Richard, Chen, Yiping, Fairhurst-Hunter, Zammy, Hill, Michael, Pozarickij, Alfred, Schmidt, Dan, Stevens, Becky, Turnbull, Iain, Yu, Canqing, Nagai, Akiko, Murakami, Yoishinori, Shiroma, Eric J, Sigurdsson, Sigurdur, Ghanbari, Mohsen, Boerwinkle, Eric, Fongang, Bernard, Wang, Ruiqi, Ikram, Mohammad K, Volker, Uwe, de Laat, Karlijn F, van Norden, Anouk GW, de Kort, Paul L, Vermeer, Sarah E, Brouwers, Paul JAM, Gons, Rob AR, den Heijer, Tom, van Dijk, Gert W, van Rooij, Frank GW, Aamodt, Anne H, Skogholt, Anne H, Willer, Cristen J, Heuch, Ingrid, Hagen, Knut, Fritsche, Lars G, Pedersen, Linda M, Ellekjaer, Hanne, Zhou, Wei, Martinsen, Amy E, Kristoffersen, Espen S, Thomas, Laurent F, Kleinschnitz, Christoph, Frantz, Stefan, Ungethum, Kathrin, Gallego-Fabrega, Cristina, Lledos, Miquel, Llucia-Carol, Laia, Sobrino, Tomas, Campos, Francisco, Castillo, Jose, Freijo, Marimar, Arenillas, Juan Francisco, Obach, Victor, Alvarez-Sabin, Jose, Molina, Carlos A, Ribo, Marc, Munoz-Narbona, Lucia, Lopez-Cancio, Elena, Millan, Monica, Diaz-Navarro, Rosa, Vives-Bauza, Cristofol, Serrano-Heras, Gemma, Segura, Tomas, Dhar, Rajat, Delgado-Mederos, Raquel, Prats-Sanchez, Luis, Camps-Renom, Pol, Blay, Natalia, Sumoy, Lauro, Marti-Fabregas, Joan, Schnohr, Peter, Jensen, Gorm B, Benn, Marianne, Afzal, Shoaib, Kamstrup, Pia R, van Setten, Jessica, van der Laan, Sander W, Vonk, Jet MJ, Kim, Bong-Jo, Curtze, Sami, Tiainen, Marjaana, Kinnunen, Janne, Menon, Vilas, Sung, Yun Ju, Yang, Chengran, Saillour-Glenisson, Florence, Gravel, Simon, Millwood, Iona Y, Gieger, Christian, Ninomiya, Toshiharu, Grabe, Hans J, Jukema, J Wouter, Rissanen, Ina L, Strbian, Daniel, Kim, Young Jin, Chen, Pei-Hsin, Mayerhofer, Ernst, Howson, Joanna MM, Adams, Hieab, Wassertheil-Smoller, Sylvia, Christensen, Kaare, Ikram, Mohammad A, Rundek, Tatjana, Worrall, Bradford B, Lathrop, G Mark, Riaz, Moeen, Simonsick, Eleanor M, Korv, Janika, Franca, Paulo HC, Zand, Ramin, Prasad, Kameshwar, Frikke-Schmidt, Ruth, Liman, Thomas, Haeusler, Karl Georg, Ruigrok, Ynte M, Heuschmann, Peter Ulrich, Longstreth, WT, Jung, Keum Ji, Bastarache, Lisa, Pare, Guillaume, Damrauer, Scott M, Chasman, Daniel I, Rotter, Jerome I, Zwart, John-Anker, Niiranen, Teemu J, Fornage, Myriam, Liaw, Yung-Po, Seshadri, Sudha, Fernandez-Cadenas, Israel, Walters, Robin G, Ruff, Christian T, Owolabi, Mayowa O, Huffman, Jennifer E, Milani, Lili, Kamatani, Yoichiro, Dichgans, Martin, Debette, Stephanie, Mishra, Aniket, Malik, Rainer, Hachiya, Tsuyoshi, Jurgenson, Tuuli, Namba, Shinichi, Posner, Daniel C, Kamanu, Frederick K, Koido, Masaru, Le Grand, Quentin, Shi, Mingyang, He, Yunye, Georgakis, Marios K, Caro, Ilana, Krebs, Kristi, Liaw, Yi-Ching, Vaura, Felix C, Lin, Kuang, Winsvold, Bendik Slagsvold, Srinivasasainagendra, Vinodh, Parodi, Livia, Bae, Hee-Joon, Chauhan, Ganesh, Chong, Michael R, Tomppo, Liisa, Akinyemi, Rufus, Roshchupkin, Gennady V, Habib, Naomi, Jee, Yon Ho, Thomassen, Jesper Qvist, Abedi, Vida, Carcel-Marquez, Jara, Nygaard, Marianne, Leonard, Hampton L, Yang, Chaojie, Yonova-Doing, Ekaterina, Knol, Maria J, Lewis, Adam J, Judy, Renae L, Ago, Tetsuro, Amouyel, Philippe, Armstrong, Nicole D, Bakker, Mark K, Bartz, Traci M, Bennett, David A, Bis, Joshua C, Bordes, Constance, Borte, Sigrid, Cain, Anael, Ridker, Paul M, Cho, Kelly, Chen, Zhengming, Cruchaga, Carlos, Cole, John W, de Jager, Phil L, de Cid, Rafael, Endres, Matthias, Ferreira, Leslie E, Geerlings, Mirjam I, Gasca, Natalie C, Gudnason, Vilmundur, Hata, Jun, He, Jing, Heath, Alicia K, Ho, Yuk-Lam, Havulinna, Aki S, Hopewell, Jemma C, Hyacinth, Hyacinth I, Inouye, Michael, Jacob, Mina A, Jeon, Christina E, Jern, Christina, Kamouchi, Masahiro, Keene, Keith L, Kitazono, Takanari, Kittner, Steven J, Konuma, Takahiro, Kumar, Amit, Lacaze, Paul, Launer, Lenore J, Lee, Keon-Joo, Lepik, Kaido, Li, Jiang, Li, Liming, Manichaikul, Ani, Markus, Hugh S, Marston, Nicholas A, Meitinger, Thomas, Mitchell, Braxton D, Montellano, Felipe A, Morisaki, Takayuki, Mosley, Thomas H, Nalls, Mike A, Nordestgaard, Borge G, O'Donnell, Martin J, Okada, Yukinori, Onland-Moret, N Charlotte, Ovbiagele, Bruce, Peters, Annette, Psaty, Bruce M, Rich, Stephen S, Rosand, Jonathan, Sabatine, Marc S, Sacco, Ralph L, Saleheen, Danish, Sandset, Else Charlotte, Salomaa, Veikko, Sargurupremraj, Muralidharan, Sasaki, Makoto, Satizabal, Claudia L, Schmidt, Carsten O, Shimizu, Atsushi, Smith, Nicholas L, Sloane, Kelly L, Sutoh, Yoichi, Sun, Yan V, Tanno, Kozo, Tiedt, Steffen, Tatlisumak, Turgut, Torres-Aguila, Nuria P, Tiwari, Hemant K, Tregouet, David-Alexandre, Trompet, Stella, Tuladhar, Anil Man, Tybjaerg-Hansen, Anne, van Vugt, Marion, Vibo, Riina, Verma, Shefali S, Wiggins, Kerri L, Wennberg, Patrik, Woo, Daniel, Wilson, Peter WF, Xu, Huichun, Yang, Qiong, Yoon, Kyungheon, Lee, Jin-Moo, Cheng, Yu-Ching, Meschia, James F, Chen, Wei Min, Sale, Michele M, Zonderman, Alan B, Evans, Michele K, Wilson, James G, Correa, Adolfo, Traylor, Matthew, Lewis, Cathryn M, Carty, Cara L, Reiner, Alexander, Haessler, Jeffrey, Langefeld, Carl D, Gottesman, Rebecca F, Yaffe, Kristine, Liu, Yong Mei, Kooperberg, Charles, Lange, Leslie A, Furie, Karen L, Arnett, Donna K, Benavente, Oscar R, Grewal, Raji P, Peddareddygari, Leema Reddy, Hveem, Kristian, Lindstrom, Sara, Wang, Lu, Smith, Erin N, Gordon, William, van Hylckama Vlieg, Astrid, de Andrade, Mariza, Brody, Jennifer A, Pattee, Jack W, Brumpton, Ben M, Suchon, Pierre, Chen, Ming-Huei, Frazer, Kelly A, Turman, Constance, Germain, Marine, MacDonald, James, Braekkan, Sigrid K, Armasu, Sebastian M, Pankratz, Nathan, Jackson, Rebecca D, Nielsen, Jonas B, Giulianini, Franco, Puurunen, Marja K, Ibrahim, Manal, Heckbert, Susan R, Bammler, Theo K, McCauley, Bryan M, Taylor, Kent D, Pankow, James S, Reiner, Alexander P, Gabrielsen, Maiken E, Deleuze, Jean-Francois, O'Donnell, Chris J, Kim, Jihye, McKnight, Barbara, Kraft, Peter, Hansen, John-Bjarne, Rosendaal, Frits R, Heit, John A, Tang, Weihong, Morange, Pierre-Emmanuel, Johnson, Andrew D, Kabrhel, Christopher, van Dijk, Ewoud J, Koudstaal, Peter J, Luijckx, Gert-Jan, Nederkoorn, Paul J, van Oostenbrugge, Robert J, Visser, Marieke C, Wermer, Marieke JH, Kappelle, L Jaap, Esko, Tonu, Metspalu, Andres, Magi, Reedik, Nelis, Mari, Irvin, Marguerite R, de Leeuw, Frank-Erik, Levi, Christopher R, Maguire, Jane, Jimenez-Conde, Jordi, Sharma, Pankaj, Sudlow, Cathie LM, Rannikmae, Kristiina, Schmidt, Reinhold, Slowik, Agnieszka, Pera, Joanna, Thijs, Vincent NS, Lindgren, Arne G, Ilinca, Andreea, Melander, Olle, Engstrom, Gunnar, Rexrode, Kathryn M, Rothwell, Peter M, Stanne, Tara M, Johnson, Julie A, Danesh, John, Butterworth, Adam S, Heitsch, Laura, Boncoraglio, Giorgio B, Kubo, Michiaki, Pezzini, Alessandro, Rolfs, Arndt, Giese, Anne-Katrin, Weir, David, Ross, Owen A, Lemmons, Robin, Soderholm, Martin, Cushman, Mary, Jood, Katarina, McDonough, Caitrin W, Bell, Steven, Linkohr, Birgit, Lee, Tsong-Hai, Putaala, Jukka, Anderson, Christopher D, Lopez, Oscar L, Jian, Xueqiu, Schminke, Ulf, Cullell, Natalia, Delgado, Pilar, Ibanez, Laura, Krupinski, Jerzy, Lioutas, Vasileios, Matsuda, Koichi, Montaner, Joan, Muino, Elena, Roquer, Jaume, Sarnowski, Chloe, Sattar, Naveed, Sibolt, Gerli, Teumer, Alexander, Rutten-Jacobs, Loes, Kanai, Masahiro, Gretarsdottir, Solveig, Rost, Natalia S, Yusuf, Salim, Almgren, Peter, Ay, Hakan, Bevan, Steve, Brown, Robert D, Carrera, Caty, Buring, Julie E, Chen, Wei-Min, Cotlarciuc, Ioana, de Bakker, Paul IW, DeStefano, Anita L, den Hoed, Marcel, Duan, Qing, Engelter, Stefan T, Falcone, Guido J, Gustafsson, Stefan, Hassan, Ahamad, Holliday, Elizabeth G, Howard, George, Hsu, Fang-Chi, Ingelsson, Erik, Harris, Tamara B, Kissela, Brett M, Kleindorfer, Dawn O, Langenberg, Claudia, Lemmens, Robin, Leys, Didier, Lin, Wei-Yu, Lorentzen, Erik, Magnusson, Patrik K, McArdle, Patrick F, Pulit, Sara L, Rice, Kenneth, Sakaue, Saori, Sapkota, Bishwa R, Tanislav, Christian, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Tzourio, Christophe, van Duijn, Cornelia M, Walters, Matthew, Wareham, Nicholas J, Amin, Najaf, Aparicio, Hugo J, Attia, John, Beiser, Alexa S, Berr, Claudine, Bustamante, Mariana, Caso, Valeria, Choi, Seung Hoan, Chowhan, Ayesha, Dartigues, Jean-Francois, Delavaran, Hossein, Dorr, Marcus, Ford, Ian, Gurpreet, Wander S, Hamsten, Anders, Hozawa, Atsushi, Ingelsson, Martin, Iwasaki, Motoki, Kaffashian, Sara, Kalra, Lalit, Kjartansson, Olafur, Kloss, Manja, Labovitz, Daniel L, Laurie, Cathy C, Li, Linxin, Lind, Lars, Lindgren, Cecilia M, Makoto, Hirata, Minegishi, Naoko, Morris, Andrew P, Muller-Nurasyid, Martina, Norrving, Bo, Ogishima, Soichi, Parati, Eugenio A, Pedersen, Nancy L, Perola, Markus, Jousilahti, Pekka, Pileggi, Silvana, Rabionet, Raquel, Riba-Llena, Iolanda, Ribases, Marta, Romero, Jose R, Rudd, Anthony G, Sarin, Antti-Pekka, Sarju, Ralhan, Satoh, Mamoru, Sawada, Norie, Sigurdsson, Asgeir, Smith, Albert, Stine, O Colin, Stott, David J, Strauch, Konstantin, Takai, Takako, Tanaka, Hideo, Touze, Emmanuel, Tsugane, Shoichiro, Uitterlinden, Andre G, Valdimarsson, Einar M, van der Lee, Sven J, Wakai, Kenji, Williams, Stephen R, Wolfe, Charles DA, Wong, Quenna, Yamaji, Taiki, Sanghera, Dharambir K, Stefansson, Kari, Martinez-Majander, Nicolas, Sobue, Kenji, Soriano-Tarraga, Carolina, Volzke, Henry, Akpa, Onoja, Sarfo, Fred S, Akpalu, Albert, Obiako, Reginald, Wahab, Kolawole, Osaigbovo, Godwin, Owolabi, Lukman, Komolafe, Morenikeji, Jenkins, Carolyn, Arulogun, Oyedunni, Ogbole, Godwin, Adeoye, Abiodun M, Akinyemi, Joshua, Agunloye, Atinuke, Fakunle, Adekunle G, Uvere, Ezinne, Olalere, Abimbola, Adebajo, Olayinka J, Chen, Junshi, Clarke, Robert, Collins, Rory, Guo, Yu, Wang, Chen, Lv, Jun, Peto, Richard, Chen, Yiping, Fairhurst-Hunter, Zammy, Hill, Michael, Pozarickij, Alfred, Schmidt, Dan, Stevens, Becky, Turnbull, Iain, Yu, Canqing, Nagai, Akiko, Murakami, Yoishinori, Shiroma, Eric J, Sigurdsson, Sigurdur, Ghanbari, Mohsen, Boerwinkle, Eric, Fongang, Bernard, Wang, Ruiqi, Ikram, Mohammad K, Volker, Uwe, de Laat, Karlijn F, van Norden, Anouk GW, de Kort, Paul L, Vermeer, Sarah E, Brouwers, Paul JAM, Gons, Rob AR, den Heijer, Tom, van Dijk, Gert W, van Rooij, Frank GW, Aamodt, Anne H, Skogholt, Anne H, Willer, Cristen J, Heuch, Ingrid, Hagen, Knut, Fritsche, Lars G, Pedersen, Linda M, Ellekjaer, Hanne, Zhou, Wei, Martinsen, Amy E, Kristoffersen, Espen S, Thomas, Laurent F, Kleinschnitz, Christoph, Frantz, Stefan, Ungethum, Kathrin, Gallego-Fabrega, Cristina, Lledos, Miquel, Llucia-Carol, Laia, Sobrino, Tomas, Campos, Francisco, Castillo, Jose, Freijo, Marimar, Arenillas, Juan Francisco, Obach, Victor, Alvarez-Sabin, Jose, Molina, Carlos A, Ribo, Marc, Munoz-Narbona, Lucia, Lopez-Cancio, Elena, Millan, Monica, Diaz-Navarro, Rosa, Vives-Bauza, Cristofol, Serrano-Heras, Gemma, Segura, Tomas, Dhar, Rajat, Delgado-Mederos, Raquel, Prats-Sanchez, Luis, Camps-Renom, Pol, Blay, Natalia, Sumoy, Lauro, Marti-Fabregas, Joan, Schnohr, Peter, Jensen, Gorm B, Benn, Marianne, Afzal, Shoaib, Kamstrup, Pia R, van Setten, Jessica, van der Laan, Sander W, Vonk, Jet MJ, Kim, Bong-Jo, Curtze, Sami, Tiainen, Marjaana, Kinnunen, Janne, Menon, Vilas, Sung, Yun Ju, Yang, Chengran, Saillour-Glenisson, Florence, Gravel, Simon, Millwood, Iona Y, Gieger, Christian, Ninomiya, Toshiharu, Grabe, Hans J, Jukema, J Wouter, Rissanen, Ina L, Strbian, Daniel, Kim, Young Jin, Chen, Pei-Hsin, Mayerhofer, Ernst, Howson, Joanna MM, Adams, Hieab, Wassertheil-Smoller, Sylvia, Christensen, Kaare, Ikram, Mohammad A, Rundek, Tatjana, Worrall, Bradford B, Lathrop, G Mark, Riaz, Moeen, Simonsick, Eleanor M, Korv, Janika, Franca, Paulo HC, Zand, Ramin, Prasad, Kameshwar, Frikke-Schmidt, Ruth, Liman, Thomas, Haeusler, Karl Georg, Ruigrok, Ynte M, Heuschmann, Peter Ulrich, Longstreth, WT, Jung, Keum Ji, Bastarache, Lisa, Pare, Guillaume, Damrauer, Scott M, Chasman, Daniel I, Rotter, Jerome I, Zwart, John-Anker, Niiranen, Teemu J, Fornage, Myriam, Liaw, Yung-Po, Seshadri, Sudha, Fernandez-Cadenas, Israel, Walters, Robin G, Ruff, Christian T, Owolabi, Mayowa O, Huffman, Jennifer E, Milani, Lili, Kamatani, Yoichiro, Dichgans, Martin, and Debette, Stephanie

Abstract

Previous genome-wide association studies (GWASs) of stroke — the second leading cause of death worldwide — were conducted predominantly in populations of European ancestry1,2. Here, in cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-European) and 1,503,898 control individuals, we identify association signals for stroke and its subtypes at 89 (61 new) independent loci: 60 in primary inverse-variance-weighted analyses and 29 in secondary meta-regression and multitrait analyses. On the basis of internal cross-ancestry validation and an independent follow-up in 89,084 additional cases of stroke (30% non-European) and 1,013,843 control individuals, 87% of the primary stroke risk loci and 60% of the secondary stroke risk loci were replicated (P < 0.05). Effect sizes were highly correlated across ancestries. Cross-ancestry fine-mapping, in silico mutagenesis analysis3, and transcriptome-wide and proteome-wide association analyses revealed putative causal genes (such as SH3PXD2A and FURIN) and variants (such as at GRK5 and NOS3). Using a three-pronged approach4, we provide genetic evidence for putative drug effects, highlighting F11, KLKB1, PROC, GP1BA, LAMC2 and VCAM1 as possible targets, with drugs already under investigation for stroke for F11 and PROC. A polygenic score integrating cross-ancestry and ancestry-specific stroke GWASs with vascular-risk factor GWASs (integrative polygenic scores) strongly predicted ischaemic stroke in populations of European, East Asian and African ancestry5. Stroke genetic risk scores were predictive of ischaemic stroke independent of clinical risk factors in 52,600 clinical-trial participants with cardiometabolic disease. Our results provide insights to inform biology, reveal potential drug targets and derive genetic risk prediction tools across ancestries.

Published
2022

33. DOMINANT PATTERNS OF ILLICIT SUBSTANCE USE AND ODDS OF STROKE AMONG WEST AFRICANS: FINDINGS FROM THE SIREN STUDY

Author

Uvere, Ezinne, primary, Akinyemi, Joshua Odunayo, additional, Okekunle, Akinkunmi Paul, additional, Asowata, Osahon Jeffery, additional, Akpa, Onoja Matthew, additional, Sarfo, Fred Stephen, additional, Ogbole, Godwin, additional, Akpalu, Albert, additional, Wahab, Kolawole, additional, Obiako, Reginald, additional, Komolafe, Morenikeji, additional, Fawale, Bimbo, additional, Owolabi, Lukman, additional, Akinyemi, Rufus, additional, Ovbiagele, Bruce, additional, and Owolabi, Mayowa, additional

Published
2022
Full Text
View/download PDF

34. COMMUNITY INSIGHT ON THE ETHICAL, LEGAL, AND SOCIAL IMPLICATIONS OF STROKE GENOMIC AND BIOBANKING RESEARCH IN SUB-SAHARAN AFRICA

Author

Nichols, Michelle, primary, Arulogun, Oyedunni, additional, Singh, Arti, additional, Olorunsogbon, Olorunyomi, additional, Uvere, Ezinne, additional, Melkiam, Sylvia, additional, Akinyemi, Joshua, additional, Jenkins, Carolyn, additional, Owolabi, Mayowa, additional, Ovbiagele, Bruce, additional, and Akinyemi, Rufus, additional

Published
2022
Full Text
View/download PDF

35. Sociodemographic and behavioural risk factors for obesity among community-dwelling older adults in Ghana and Nigeria: A secondary analysis of data from the SIREN study.

Author

Akpa, Onoja M., Okekunle, Akinkunmi P., Sarfo, Fred S., Akinyemi, Rufus O., Akpalu, Albert, Wahab, Kolawole W., Komolafe, Morenikeji, Obiako, Reginald, Owolabi, Lukman, Jenkins, Carolyn, Abiodun, Adeoye, Ogbole, Godwin, Fawale, Bimbo, Akinyemi, Joshua, Agunloye, Atinuke, Uvere, Ezinne O., Fakunle, Adekunle, Ovbiagele, Bruce, and Owolabi, Mayowa O.

Subjects
OBESITY risk factors, OBESITY, MIDDLE-income countries, CONFIDENCE intervals, RISK assessment, T-test (Statistics), INDEPENDENT living, LOW-income countries, RESEARCH funding, DESCRIPTIVE statistics, HEALTH behavior, CHI-squared test, DATA analysis software, SOCIODEMOGRAPHIC factors, ODDS ratio, SECONDARY analysis, OLD age
Abstract

Objectives: To explore the prevalence and risk factors of obesity among older adults from low- and middle-income countries (LMICs). Methods: This is a secondary analysis of data obtained from the SIREN study through in-person interviews and measurements from healthy stroke-free older adults (≥60 years). Overweight/obesity was defined as body mass index ≥ 25 kg/m2. Abdominal obesity was defined as waist-to-hip ratio (WHR) of >0.90 for males and >0.85/females or waist circumference (WC) of >102 cm for males/>88 cm for females. Adjusted odds ratio (aORs) with 95% confidence interval (CIs) of the relationship between obesity and sociodemographic factors were assessed at P < 0.05. Results: Overall, 47.5% of participants were overweight/obese, 76.6% had a larger than recommended WHR, and 54.4% had a larger than recommended WC. Abdominal obesity (WC; aOR: 9.43, CI: 6.99–12.50), being a Nigerian (aOR: 0.55; CI: 0.42–0.72), living in an urban setting (aOR: 1.92; CI: 1.49–2.46), earning > $100/month (aOR: 1.53; CI: 1.19–1.96), and having formal education (aOR: 1.42; CI: 1.08–1.87) were associated with overweight/obesity. Conclusion: Living in urban settings, earning a higher income, and having a formal education were associated with a higher odds of obesity among older adults from LMICs. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

36. Patient- and Health Facility-Level Determinants of Stroke Fatality Across 15 Large Hospitals in Ghana & Nigeria

Author

Sarfo, Fred S., primary, Onoja, Akpa, additional, Ovbiagele, Bruce, additional, Akpalu, Albert, additional, Wahab, Kolawole, additional, Obiako, Reginald, additional, Morenikeji, Komolafe, additional, Owolabi, Lukman, additional, Ogbole, Godwin, additional, Calys-Tagoe, Benedict, additional, Uvere, Ezinne, additional, Sanni, Taofeek, additional, Gebregziabher, Mulugeta, additional, Salaam, Abdul, additional, Akintunde, Adeseye A., additional, olowookere, samuel, additional, Ibinaiye, Phillip, additional, Akinyemi, Joshua, additional, Uwanuruochi, Kelechukwu, additional, Olayemi, Balogun, additional, Odunlami, Olufemi A., additional, Abunimye, Esther, additional, Arulogun, Oyedunni, additional, Isah, Sulaiman Y., additional, Abubakar, Sani A., additional, Adebayo, Oladimeji, additional, Adebayo, Phillip, additional, Shidali, Vincent, additional, Chukwuonye, Innocent I., additional, Akpalu, Josephine, additional, Fakunle, Adekunle, additional, Asowata, Osahon J., additional, Sanya, Emmanuel O., additional, Amusa, Ganiyu, additional, Onyeonoro, Ugochukwu Uchenna, additional, Ogunmodede, James A., additional, Sule, Abdullaleef G., additional, Akinsanya, Cynthia, additional, Mensah, Yaw, additional, Oyinloye, Olalekan I., additional, Appiah, Lambert, additional, Agunloye, Atinuke M., additional, Osaigbovo, Godwin O., additional, Olabinri, Eunice, additional, Kolo, Phillip M., additional, Okeke, Obiora, additional, Adeoye, Abiodun M., additional, Ajose, Olabamiji, additional, Jenkins, Carolyn, additional, Lackland, Daniel T., additional, Egberongbe, Adedeji A., additional, Adeniji, Olaleye, additional, Adeleye, Osinmhiaherhuo Ohifemen, additional, Tiwari, Hermant K., additional, Laryea, Ruth Y., additional, Olunuga, Taiwo, additional, Akinwande, Kazeem S., additional, Imoh, Lucius, additional, Ogah, Okechukwu S., additional, Melikam, Ezinne, additional, Adebolaji, Adeyemo, additional, Oguike, Wisdom, additional, Ogunronbi, Mayowa, additional, Adeniyi, Wasiu, additional, Olugbo, Obiabo Y., additional, Bello, Abiodun H., additional, Ohagwu, Kenneth A., additional, Ogunjimi, Luqman, additional, Agyekum, Francis, additional, Iheonye, Henry, additional, Adesina, Julius, additional, Diala, Samuel, additional, Dambatta, Hamisu A., additional, Ikubor, Joyce, additional, Singh, Arti, additional, Adamu, Sheila, additional, Obese, Vida, additional, Adesie, Nathaniel, additional, Owusu, Dorcas, additional, Ampofo, Michael, additional, Tagge, Raelle, additional, Efidi, Richard, additional, Fawale, Bimbo, additional, Yaria, Joseph O., additional, Akinyemi, Rufus, additional, OWOLABI, Mayowa, additional, and Study, SIREN, additional

Published
2022
Full Text
View/download PDF

37. African Rigorous Innovative Stroke Epidemiological Surveillance: Protocol for a Community-Based Mobile-Health Study

Author

Popoola, Oluwafemi, primary, Ovbiagele, Bruce, additional, Arulogun, Oyedunni, additional, Akinyemi, Joshua, additional, Akinyemi, Rufus, additional, Uvere, Ezinne, additional, Akpa, Onoja, additional, Salami, Ayodeji, additional, Taiwo, Olalekan, additional, Olaniyan, Olanrewaju, additional, Walker, Richard, additional, Jenkins, Carolyn, additional, and Owolabi, Mayowa, additional

Published
2021
Full Text
View/download PDF

38. Multilingual Validation of the Questionnaire for Verifying Stroke-Free Status in West Africa

Author

Sarfo, Fred, Gebregziabher, Mulugeta, Ovbiagele, Bruce, Akinyemi, Rufus, Owolabi, Lukman, Obiako, Reginald, Akpa, Onoja, Armstrong, Kevin, Akpalu, Albert, Adamu, Sheila, Obese, Vida, Boa-Antwi, Nana, Appiah, Lambert, Arulogun, Oyedunni, Mensah, Yaw, Adeoye, Abiodun, Tosin, Aridegbe, Adeleye, Osimhiarherhuo, Tabi-Ajayi, Eric, Phillip, Ibinaiye, Sani, Abubakar, Isah, Suleiman, Tabari, Nasir, Mande, Aliyu, Agunloye, Atinuke, Ogbole, Godwin, Akinyemi, Joshua, Laryea, Ruth, Melikam, Sylvia, Uvere, Ezinne, Adekunle, Gregory, Kehinde, Salaam, Azuh, Paschal, Dambatta, Abdul, Ishaq, Naser, Saulson, Raelle, Arnett, Donna, Tiwari, Hemnant, Jenkins, Carolyn, Lackland, Dan, and Owolabi, Mayowa

Published
2016
Full Text
View/download PDF

40. African Rigorous Innovative Stroke Epidemiological Surveillance: Protocol for a Community-Based Mobile-Health Study.

Author

Popoola, Oluwafemi, Ovbiagele, Bruce, Arulogun, Oyedunni, Akinyemi, Joshua, Akinyemi, Rufus, Uvere, Ezinne, Akpa, Onoja, Salami, Ayodeji, Taiwo, Olalekan, Olaniyan, Olanrewaju, Walker, Richard, Jenkins, Carolyn, and Owolabi, Mayowa

Subjects
STROKE, INTERNET telephony, HEALTH literacy
Abstract

Despite projections of stroke being a leading cause of mortality in Africa, reliable estimates of stroke burden on the continent using rigorous methods are not available. We aimed to implement a mobile-Health community-based interactive Stroke Information and Surveillance System to sustainably measure stroke burden and improve stroke health literacy and outcomes in urban and rural sites in Nigeria. African Rigorous Innovative Stroke Epidemiological Surveillance (ARISES) is an observational cohort study, which will be conducted in urban (Ibadan North LGA Ward 3) and rural (Ibarapa Central LGA) sites with a combined base population of over 80,000 people. The study will use a consultative approach to establish an mHealth-based Stroke Information and Surveillance System comprising a Stroke Alert System and a Stroke Finding System. These systems will enable the community to report stroke events and the research team/health workers find stroke cases using phone calls, short message service, and Voice Over Internet Protocols (VoIP). We will update community household data and geo-locate all households. Over the 5 years of the study, the system will collect information on stroke events and educate the community about this disease. Reported stroke cases will be clinically adjudicated at home and in prespecified health facilities. Baseline and endline community surveys will be conducted to assess stroke occurrence and other important study variables. The proportion of strokes alerted and found will be determined over the study period. Focus group discussions and key informant interviews will be conducted to understand community stroke literacy and perspectives. The study will also assess any impact of these efforts on time from stroke onset to referral, community uptake of orthodox health services for stroke patients. ARISES is anticipated to establish proof of concept about using mHealth for stroke surveillance in Africa. The potential impact of the SISS on improving patient outcomes will also be determined. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

41. Risk Factor Characterization of Ischemic Stroke Subtypes Among West Africans.

Author

Sarfo, Fred S., Ovbiagele, Bruce, Akpa, Onoja, Akpalu, Albert, Wahab, Kolawole, Obiako, Reginald, Komolafe, Morenikeji, Owolabi, Lukman, Ogbole, Godwin, Calys-Tagoe, Benedict, Fakunle, Adekunle, Sanni, Taofeek, Mulugeta, Gebregziabher, Abdul, Salaam, Akintunde, Adeseye A., Olowookere, Samuel, Uvere, Ezinne O., Ibinaiye, Philip, Akinyemi, Joshua, and Uwanuruochi, Kelechukwu

Published
2022
Full Text
View/download PDF

42. Unraveling the Ethical, Legal, and Social Implications of Neurobiobanking and Stroke Genomic Research in Africa: A Study Protocol of the African Neurobiobank for Precision Stroke Medicine ELSI Project

Author

Akinyemi, Rufus O., primary, Jenkins, Carolyn, additional, Nichols, Michelle, additional, Singh, Arti, additional, Wahab, Kolawole, additional, Akpalu, Albert, additional, Sarfo, Fred S., additional, Owolabi, Lukman F., additional, Obiako, Reginald, additional, Akinyemi, Joshua, additional, Ojebuyi, Babatunde, additional, Adigun, Muyiwa, additional, Musbahu, Rabiu, additional, Bello, Abiodun, additional, Titiloye, Musibau, additional, Calys-Tagoe, Benedict, additional, Ogunronbi, Mayowa, additional, Uvere, Ezinne, additional, Laryea, Ruth, additional, Fakunle, Adekunle, additional, Adeleye, Osi, additional, Olorunsogbon, Olorunyomi, additional, Ojo, Adebayo, additional, Adesina, Deborah, additional, Mensah, Nathaniel, additional, Oguike, Wisdom, additional, Coleman, Nathaniel, additional, Mande, Aliyu, additional, Uthman, Muhammed, additional, Kalaria, Rajesh N., additional, Jegede, Ayodele, additional, Owolabi, Mayowa, additional, Ovbiagele, Bruce, additional, and Arulogun, Oyedunni, additional

Published
2020
Full Text
View/download PDF

43. The role of context in implementation research for non-communicable diseases : Answering the 'how-to' dilemma

Author

Daivadanam, Meena, Ingram, Maia, Annerstedt, Kristi Sidney, Parker, Gary, Bobrow, Kirsty, Dolovich, Lisa, Gould, Gillian, Riddell, Michaela, Vedanthan, Rajesh, Webster, Jacqui, Absetz, Pilvikki, Alvesson, Helle Molsted, Androutsos, Odysseas, Chavannes, Niels, Cortez, Briana, Devarasetty, Praveen, Fottrell, Edward, Gonzalez-Salazar, Francisco, Goudge, Jane, Herasme, Omarys, Jennings, Hannah, Kapoor, Deksha, Kamano, Jemima, Kasteleyn, Marise J., Kyriakos, Christina, Manios, Yannis, Mogulluru, Kishor, Owolabi, Mayowa, Lazo-Porras, Maria, Silva, Wnurinham, Thrift, Amanda, Uvere, Ezinne, Webster, Ruth, van der Kleij, Rianne, van Olmen, Josefien, Vardavas, Constantine, Zhang, Puhong, Almeda-Valdes, Paloma, Britton, John, Cristobal, Fortunato, Delobelle, Peter, Gonzalez, Clicerio, Guwatudde, David, Gyamfi, Joyce, Johnson, Claire, Kirkham, Renae, Lopez-Jaramillo, Patricio, Lucero, Vilarmina Ponce, Mills, Katherine, Oldenburg, Brian, Patel, Anushka, Saulson, Raelle, Silva, Ninha, Trieu, Kathy, Daivadanam, Meena, Ingram, Maia, Annerstedt, Kristi Sidney, Parker, Gary, Bobrow, Kirsty, Dolovich, Lisa, Gould, Gillian, Riddell, Michaela, Vedanthan, Rajesh, Webster, Jacqui, Absetz, Pilvikki, Alvesson, Helle Molsted, Androutsos, Odysseas, Chavannes, Niels, Cortez, Briana, Devarasetty, Praveen, Fottrell, Edward, Gonzalez-Salazar, Francisco, Goudge, Jane, Herasme, Omarys, Jennings, Hannah, Kapoor, Deksha, Kamano, Jemima, Kasteleyn, Marise J., Kyriakos, Christina, Manios, Yannis, Mogulluru, Kishor, Owolabi, Mayowa, Lazo-Porras, Maria, Silva, Wnurinham, Thrift, Amanda, Uvere, Ezinne, Webster, Ruth, van der Kleij, Rianne, van Olmen, Josefien, Vardavas, Constantine, Zhang, Puhong, Almeda-Valdes, Paloma, Britton, John, Cristobal, Fortunato, Delobelle, Peter, Gonzalez, Clicerio, Guwatudde, David, Gyamfi, Joyce, Johnson, Claire, Kirkham, Renae, Lopez-Jaramillo, Patricio, Lucero, Vilarmina Ponce, Mills, Katherine, Oldenburg, Brian, Patel, Anushka, Saulson, Raelle, Silva, Ninha, and Trieu, Kathy

Abstract

Introduction Understanding context and how this can be systematically assessed and incorporated is crucial to successful implementation. We describe how context has been assessed (including exploration or evaluation) in Global Alliance for Chronic Diseases (GACD) implementation research projects focused on improving health in people with or at risk of chronic disease and how contextual lessons were incorporated into the intervention or the implementation process. Methods Using a web-based semi-structured questionnaire, we conducted a cross-sectional survey to collect quantitative and qualitative data across GACD projects (n = 20) focusing on hypertension, diabetes and lung diseases. The use of context-specific data from project planning to evaluation was analyzed using mixed methods and a multi-layered context framework across five levels; 1) individual and family, 2) community, 3) healthcare setting, 4) local or district level, and 5) state or national level. Results Project teams used both qualitative and mixed methods to assess multiple levels of context (avg. = 4). Methodological approaches to assess context were identified as formal and informal assessments, engagement of stakeholders, use of locally adapted resources and materials, and use of diverse data sources. Contextual lessons were incorporated directly into the intervention by informing or adapting the intervention, improving intervention participation or improving communication with participants/stakeholders. Provision of services, equipment or information, continuous engagement with stakeholders, feedback for personnel to address gaps, and promoting institutionalization were themes identified to describe how contextual lessons are incorporated into the implementation process. Conclusions Context is regarded as critical and influenced the design and implementation of the GACD funded chronic disease interventions. There are different approaches to assess and incorporate context as demonstrated by this s

Published
2019
Full Text
View/download PDF

44. Knowledge, attitudes and practices related to stroke in Ghana and Nigeria: A SIREN call to action

Author

Jenkins, Carolyn, primary, Ovbiagele, Bruce, additional, Arulogun, Oyedunni, additional, Singh, Arti, additional, Calys-Tagoe, Benedict, additional, Akinyemi, Rufus, additional, Mande, Aliyu, additional, Melikam, Ezinne Sylvia, additional, Akpalu, Albert, additional, Wahab, Kolawole, additional, Sarfo, Fred Stephen, additional, Sanni, Taofeeq, additional, Osaigbovo, Godwin, additional, Tiwari, Hemant K., additional, Obiako, Reginald, additional, Shidali, Vincent, additional, Ibinaiye, Philip, additional, Akpalu, Josephine, additional, Ogbole, Godwin, additional, Owolabi, Lukman, additional, Uvere, Ezinne, additional, Taggae, Raelle, additional, Adeoye, Abiodun Moshood, additional, Gebregziabher, Mulugeta, additional, Akintunde, Adeseye, additional, Adebayo, Oladimeji, additional, Oguntade, Ayodipupo, additional, Bisi, Ayotunde, additional, Ohagwu, Kenneth, additional, Laryea, Ruth, additional, Olowoniyi, Peter, additional, Yahaya, Isah Suleiman, additional, Olowookere, Samuel, additional, Adeyemi, Frederick, additional, Komolafe, Morenikeji, additional, Fawale, Michael Bimbola, additional, Sunmonu, Taofiki, additional, Onyeonoro, Ugochukwu, additional, Imoh, Lucius Chidiebere, additional, Oguike, Wisdom, additional, Olunuga, Taiye, additional, Kolo, Phillip, additional, Ogah, Okechukwu S., additional, Efidi, Richard, additional, Chukwuonye, Ijezie, additional, Bock-Oruma, Andrew, additional, Owusu, Dorcas, additional, Odo, Chidi Joseph, additional, Faniyan, Moyinoluwalogo, additional, Ohnifeman, Osimhiarherhuo Adeleye, additional, Ajose, Olabanji, additional, Ogunjimi, Luqman, additional, Johnson, Shelia, additional, Ganiyu, Amusa, additional, Olowoyo, Paul, additional, Fakunle, Adekunle Gregory, additional, Tolulope, Afolaranmi, additional, Farombi, Temitope, additional, Obiabo, Monica Oghome, additional, and Owolabi, Mayowa, additional

Published
2018
Full Text
View/download PDF

46. Stroke-related stigma among West Africans: Patterns and predictors

Author

Abeba A. Teklehaimanot, Nathaniel Mensah, Raelle Saulson, Carolyn Jenkins, Mayowa O. Owolabi, Arti Singh, Bruce Ovbiagele, Fred Stephen Sarfo, Suparna Qanungo, Uvere Ezinne, Michelle Nichols, and Mulugeta Gebregziabher

Subjects
Gerontology, Male, medicine.medical_specialty, medicine.medical_treatment, Social Stigma, Stigma (botany), Article, 03 medical and health sciences, 0302 clinical medicine, Quality of life, medicine, Humans, 030212 general & internal medicine, Stroke survivor, Psychiatry, Stroke, Depression (differential diagnoses), Aged, Retrospective Studies, Psychiatric Status Rating Scales, Analysis of Variance, Rehabilitation, business.industry, Middle Aged, medicine.disease, West african, Africa, Western, Neurology, Cohort, Quality of Life, Female, Neurology (clinical), business, 030217 neurology & neurosurgery
Abstract

Disability-adjusted life-years lost after stroke in LowMiddle-Income Countries (LMICs) is almost seven times those lost in High-income countries. Although individuals living with chronic neurological and mental disorders are prone to stigma, there is a striking paucity of literature on stroke-related stigma particularly from LMICs.To assess the prevalence, severity, determinants and psycho-social consequences of stigma among LMIC stroke survivors.Between November 2015 and February 2016, we conducted a cross-sectional survey of 200 consecutive stroke survivors attending a neurology clinic in a tertiary medical center in Ghana. The validated 8-Item Stigma Scale for Chronic Illness (SSCI-8) questionnaire was administered to study participants to assess internalized and enacted domains of stigma at the personal dimension with further adaptation to capture family and community stigma experienced by stroke participants. Responses on the SSCI-8 were scored from 1 to 5 for each item, where 1=never, 2=rarely, 3=sometimes, 4=often and 5=always with a score range of 8-40. Demographic and clinical data on stroke type and severity as well as depression and Health-Related Quality of Life indicators were also collected. Predictors of stroke-related stigma were assessed using Linear Models (GLM) via Proc GENMOD in SAS 9.4.105 (52.5%) subjects recruited were males and the mean±SD age of stroke survivors in this survey was 62.0±14.4years. Mean SSCI-8 score was highest for personal stigma (13.7±5.7), which was significantly higher than family stigma (11.9±4.6; p=0.0005) and social/community stigma (11.4±4.4; p0.0001). Approximately 80% of the cohort reported experiencing mild-to-moderate degrees of stigma. A graded increase in scores on the Geriatric Depression Scale and Centre for Epidemiological Studies-Depression scale was observed across the three categories. Living in an urban setting was associated with higher SSCI-8 scores. Moreover, stroke subjects with more severe post-stroke residual symptom deficits reported a significantly higher frequency of stigma.Four out of five stroke survivors in this Ghanaian cohort reported experiencing some form of stigma. Stigmatized individuals were also more likely to be depressed and have lower levels of quality of life. Further studies are required to assess the consequences of stigma from stroke in LMIC.

Published
2016

47. Knowledge, attitudes and practices of West Africans on genetic studies of stroke: Evidence from the SIREN Study

Author

Akinyemi, Rufus O, primary, Sarfo, Fred S, additional, Akinyemi, Joshua, additional, Singh, Arti, additional, Onoja Akpa, Matthew, additional, Akpalu, Albert, additional, Owolabi, Lukman, additional, Adeoye, Abiodun M., additional, Obiako, Reginald, additional, Wahab, Kolawole, additional, Sanya, Emmanuel, additional, Komolafe, Morenikeji, additional, Ogbole, Godwin, additional, Fawale, Michael, additional, Adebayo, Philip, additional, Osaigbovo, Godwin, additional, Sunmonu, Taofiki, additional, Olowoyo, Paul, additional, Chukwuonye, Innocent, additional, Obiabo, Yahaya, additional, Adeniji, Olaleye, additional, Fakunle, Gregory, additional, Melikam, Ezinne, additional, Saulson, Raelle, additional, Yaria, Joseph, additional, Uwanruochi, Kelechi, additional, Ibinaiye, Phillip, additional, Amusa, Ganiyu Adeniyi, additional, Yahaya, Isah Suleiman, additional, Dambatta, Abdullahi Hamisu, additional, Faniyan, Mercy, additional, Olowoniyi, Peter, additional, Bock-Oruma, Andrew, additional, Joseph, Odo Chidi, additional, Oguntade, Ayodipupo, additional, Kolo, Philip, additional, Laryea, Ruth, additional, Lakoh, Sulaiman, additional, Uvere, Ezinne, additional, Farombi, Temitope, additional, Akpalu, Josephine, additional, Oyinloye, Olalekan, additional, Appiah, Lambert, additional, Calys-Tagoe, Benedict, additional, Shidali, Vincent, additional, Tabari, Nasir Abdulkadir, additional, Adebayo, Oladimeji, additional, Efidi, Richard, additional, Adeleye, Osi, additional, Owusu, Dorcas, additional, Ogunjimi, Luqman, additional, Aridegbe, Olumayowa, additional, Imoh, Chidiebere Lucius, additional, Sanni, Taofeeq, additional, Gebreziabher, Mulugeta, additional, Hemant, Tiwari, additional, Arulogun, Oyedunni, additional, Ogunniyi, Adesola, additional, Jenkins, Carolyn, additional, Owolabi, Mayowa, additional, and Ovbiagele, Bruce, additional

Published
2018
Full Text
View/download PDF

48. The epidemiology of stroke in Africa: A systematic review of existing methods and new approaches

Author

Owolabi, Mayowa, primary, Olowoyo, Paul, additional, Popoola, Femi, additional, Lackland, Daniel, additional, Jenkins, Carolyn, additional, Arulogun, Oyedunni, additional, Akinyemi, Rufus, additional, Akinyemi, Odunayo, additional, Akpa, Onoja, additional, Olaniyan, Olanrewaju, additional, Uvere, Ezinne, additional, Kehinde, Issa, additional, Selassie, Anbesaw, additional, Gebregziabher, Mulugeta, additional, Tagge, Raelle, additional, and Ovbiagele, Bruce, additional

Published
2017
Full Text
View/download PDF

50. Exploring Overlaps Between the Genomic and Environmental Determinants of LVH and Stroke: A Multicenter Study in West Africa

Author

Adeoye, Abiodun M., primary, Ovbiagele, Bruce, additional, Kolo, Philip, additional, Appiah, Lambert, additional, Aje, Akinyemi, additional, Adebayo, Oladimeji, additional, Sarfo, Fred, additional, Akinyemi, Joshua, additional, Adekunle, Gregory, additional, Agyekum, Francis, additional, Shidali, Vincent, additional, Ogah, Okechukwu, additional, Lackland, Dan, additional, Gebregziabher, Mulugeta, additional, Arnett, Donna, additional, Tiwari, Hemant K., additional, Akinyemi, Rufus, additional, Olagoke, Ojo Olakanmi, additional, Oguntade, Ayodipupo Sikiru, additional, Olunuga, Taiwo, additional, Uwanruochi, Kelechi, additional, Jenkins, Carolyn, additional, Adadey, Patrick, additional, Iheonye, Henry, additional, Owolabi, Lukman, additional, Obiako, Reginald, additional, Akinjopo, Samuel, additional, Armstrong, Kevin, additional, Akpalu, Albert, additional, Fakunle, Adekunle, additional, Saulson, Raelle, additional, Aridegbe, Mayowa, additional, Olowoyo, Paul, additional, Osaigbovo, Godwin, additional, Akpalu, Josephine, additional, Fawale, Bimbo, additional, Adebayo, Philip, additional, Arulogun, Oyedunni, additional, Ibinaiye, Philip, additional, Agunloye, Atinuke, additional, Ishaq, Naser, additional, Wahab, Kolawole, additional, Akpa, Onoja, additional, Adeleye, Omisore, additional, Bock-Oruma, Andrew, additional, Ogbole, Godwin, additional, Melikam, Sylvia, additional, Yaria, Joseph, additional, Ogunjimi, Luqman, additional, Salaam, Abdul, additional, Sunmonu, Taofiki, additional, Makanjuola, Akintomiwa, additional, Farombi, Temitope, additional, Laryea, Ruth, additional, Uvere, Ezinne, additional, Kehinde, Salaam, additional, Chukwuonye, Innocent, additional, Azuh, Paschal, additional, Komolafe, Morenikeji, additional, Akintunde, Adeseye, additional, Obiabo, Olugbo, additional, Areo, Olusegun, additional, Kehinde, Issa, additional, Amusa, Adeniyi G., additional, Owolabi, Mayowa, additional, and HAfrica Consortium, SIREN Team as part of, additional

Published
2017
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results