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3 results on '"Urt'eva TA"'

1. [Effect of encoding amino acids on associative learning of honeybee Apis mellifera L].

Author

Chalisova NI, Kamyshev NG, Lopatina NG, Kontsevaia EA, Urt'eva SA, and Urt'eva TA

Subjects
Amino Acids metabolism, Animals, Association Learning physiology, Bees metabolism, Feeding Behavior drug effects, Memory, Long-Term drug effects, Memory, Short-Term drug effects, Amino Acids pharmacology, Association Learning drug effects, Bees physiology
Published
2011

2. [The protective effect of the amino acids in the action of cytostatic in culture of the lymphoid tissue of young and aged rats].

Author

Chalisova NI, Urt'eva SA, Urt'eva TA, Bunina AA, Zhekalov AN, Smirnov AV, and Kontsevaia EA

Subjects
Aging pathology, Animals, Apoptosis drug effects, Cell Proliferation drug effects, Dose-Response Relationship, Drug, Male, Rats, Rats, Wistar, Tissue Culture Techniques, Aging drug effects, Amino Acids pharmacology, Cyclophosphamide adverse effects, Cytostatic Agents adverse effects, Protective Agents pharmacology, Spleen drug effects, Spleen pathology
Abstract

The effect of the cyclophosphane and amino acids with side charge radicales (basic--lysine, arginine, acid--asparagine and glutamic acid) on the cell proliferation and apoptosis development in lymphoide tissue explants in young rats (at age 3 months old) and old rats (at age 24 months old) was investigated in organotypic tissue culture. All amino acids in concentration of 10(-12) M stimulated proliferation in explants' growth zone of young rats and two amino acids (arginine, glutamic acid)--of old rats. Cyclophosphane in concentration of 1 mg/ml inhibited the explant cell proliferation. A delay of the cyclophosphane inhibitory effect was observed under the combined administration into the culture of cyclophosphane with each of the amino acids having a stimulated effect. Thus, the amino acids can possess a protective effect by action of DNA synthesis inhibitors both in young and old rats.

Published
2010

3. [The effect of the amino acids and cardiogen on the development of myocard tissue culture from young and old rats].

Author

Chalisova NI, Lesniak VV, Balykina NA, Urt'eva SA, Urt'eva TA, Sukhonos IuA, and Zhekalov AN

Subjects
Age Factors, Animals, Cell Proliferation, Organ Culture Techniques, Rats, Aging drug effects, Amino Acids pharmacology, Apoptosis drug effects, Myocardium cytology, Peptides pharmacology, Tumor Suppressor Protein p53
Abstract

The effect of 20 amino acids and the synthetic tetrapeptide cardiogen in concentration 10(-12) M was investigated in organotypic tissue culture on the cell proliferation and apoptosis development in myocard tissue explant in 3- and 24-months old rats. 7 of 20 amino acids stimulated the cell proliferation in the young rats. In the same time, only 2 amino acids were active in myocard culture from the old rats. The tetrapeptide cardiogen demonstrated the great stimulating effect on the proliferation both in tissues from young and old rats. The immunohistochemical study demonstrated a decrease of the p53 protein expression by cardiogen action. This fact can testify that cardiogen inhibits the apoptosis process in the myocard tissue.

Published
2009

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