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5. Artificial Intelligence–Enabled Quantitative Coronary Plaque and Hemodynamic Analysis for Predicting Acute Coronary Syndrome

Author

Koo, Bon-Kwon, Yang, Seokhun, Jung, Jae Wook, Zhang, Jinlong, Lee, Keehwan, Hwang, Doyeon, Lee, Kyu-Sun, Doh, Joon-Hyung, Nam, Chang-Wook, Kim, Tae Hyun, Shin, Eun-Seok, Chun, Eun Ju, Choi, Su-Yeon, Kim, Hyun Kuk, Hong, Young Joon, Park, Hun-Jun, Kim, Song-Yi, Husic, Mirza, Lambrechtsen, Jess, Jensen, Jesper M., Nørgaard, Bjarne L., Andreini, Daniele, Maurovich-Horvat, Pal, Merkely, Bela, Penicka, Martin, de Bruyne, Bernard, Ihdayhid, Abdul, Ko, Brian, Tzimas, Georgios, Leipsic, Jonathon, Sanz, Javier, Rabbat, Mark G., Katchi, Farhan, Shah, Moneal, Tanaka, Nobuhiro, Nakazato, Ryo, Asano, Taku, Terashima, Mitsuyasu, Takashima, Hiroaki, Amano, Tetsuya, Sobue, Yoshihiro, Matsuo, Hitoshi, Otake, Hiromasa, Kubo, Takashi, Takahata, Masahiro, Akasaka, Takashi, Kido, Teruhito, Mochizuki, Teruhito, Yokoi, Hiroyoshi, Okonogi, Taichi, Kawasaki, Tomohiro, Nakao, Koichi, Sakamoto, Tomohiro, Yonetsu, Taishi, Kakuta, Tsunekazu, Yamauchi, Yohei, Bax, Jeroen J., Shaw, Leslee J., Stone, Peter H., and Narula, Jagat

Published
2024
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7. Interaction of AI-Enabled Quantitative Coronary Plaque Volumes on Coronary CT Angiography, FFRCT, and Clinical Outcomes: A Retrospective Analysis of the ADVANCE Registry

Author

Dundas, James, Leipsic, Jonathon, Fairbairn, Timothy, Ng, Nicholas, Sussman, Vida, Guez, Ilana, Rosenblatt, Rachael, Hurwitz Koweek, Lynne M., Douglas, Pamela S., Rabbat, Mark, Pontone, Gianluca, Chinnaiyan, Kavitha, de Bruyne, Bernard, Bax, Jeroen J., Amano, Tetsuya, Nieman, Koen, Rogers, Campbell, Kitabata, Hironori, Sand, Niels P.R., Kawasaki, Tomohiro, Mullen, Sarah, Huey, Whitney, Matsuo, Hitoshi, Patel, Manesh R., Norgaard, Bjarne L., Ahmadi, Amir, and Tzimas, Georgios

Published
2024
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8. Valve-in-Valve Transcatheter Mitral Valve Replacement: A Large First-in-Human 13-Year Experience

Author

Akodad, Mariama, Trpkov, Cvet, Cheung, Anson, Ye, Jian, Chatfield, Andrew G., Alosail, Abdulmajeed, Besola, Laura, Yu, Maggie, Leipsic, Jonathon A., Lounes, Youcef, Meier, David, Yang, Cathevine, Nestelberger, Thomas, Tzimas, Georgios, Sathananthan, Janarthanan, Wood, David A., Moss, Rob R., Blanke, Philipp, Sathananthan, Gnalini, and Webb, John G.

Published
2023
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15. Artificial Intelligence, Virtual Reality, and the Metaverse in Cardiovascular Imaging: Tools for Transformation or Technological Overreach?

Author

Skalidis, Ioannis, Tzimas, Georgios, Antiochos, Panagiotis, Suc, Gaspard, Lu, Henri, Salihu, Adil, Fournier, Stephane, Muller, Olivier, Maurizi, Niccolo', and Arangalage, Dimitri

Subjects
*CARDIOVASCULAR disease diagnosis, *COMPUTER simulation, *DIAGNOSTIC imaging, *MEDICAL education, *ARTIFICIAL intelligence, *VIRTUAL reality, *DEEP learning, *MACHINE learning, *ACCURACY, *AUTOMATION, *USER interfaces, *ALGORITHMS
Abstract

The article focuses on the potential impact of emerging technologies like artificial intelligence, virtual reality, and the metaverse on cardiovascular imaging. Topics include the role of artificial intelligence in enhancing diagnostic accuracy and workflow, the limited practical applications of virtual reality in clinical practice, and the challenges facing the metaverse in transforming patient care and clinician collaboration.

Published
2024
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16. Multi‐Modality Imaging to Detect Ischemic and Valvular Heart Disease in Adult Cancer Patients.

Author

Hugelshofer, Sarah, Giacomuzzi‐Moore, Bianca, Auberson, Denise, Tzimas, Georgios, Kamani, Christel H., Masi, Ambra, Monney, Pierre, Arangalage, Dimitri, and Poku, Nana K.

Subjects
RISK assessment, MYOCARDIAL ischemia, DIAGNOSTIC imaging, RADIOTHERAPY, HEART valve diseases, CANCER patients, CANCER chemotherapy, CARDIOTOXICITY, CASE studies, CORONARY artery disease, ADULTS
Abstract

Thanks to impressive advances in the field of oncology over the last 30 years, there has been a significant rise in cancer survivors. Nowadays, cardiovascular disease is one of the leading causes of death in this patient population. Coronary artery disease (CAD) is a major problem due to shared risk factors, an aging population and in many cases induced and/or accelerated atherosclerosis by antitumoral treatment during and even decades after the end of cancer therapy. Furthermore, the presence of CAD or valvular heart disease (VHD) at the time point of cancer diagnosis largely increases the risk of any cancer therapy‐related cardiovascular toxicity (CTR‐CVT). It is therefore of utmost importance to detect CAD and VHD before, during, and after certain types of chemotherapy, target therapies, and radiotherapy. Multimodality cardiovascular imaging plays a central role in this vulnerable population where individual risk stratification and multidisciplinary decision‐making are critical. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Evaluation of the HANDOC score and the 2023 ISCVID and ESC Duke clinical criteria for the diagnosis of infective endocarditis among patients with streptococcal bacteremia

Author

Fourre, Nicolas, primary, Zimmermann, Virgile, additional, Senn, Laurence, additional, Monney, Pierre, additional, Tzimas, Georgios, additional, Caruana, Giorgia, additional, Tozzi, Piergiorgio, additional, Kirsch, Matthias, additional, Guery, Benoit, additional, and Papadimitriou-Olivgeris, Matthaios, additional

Published
2024
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18. Head-to-Head Comparison and Temporal Trends of Cardiac MRI Recommendations in ESC versus ACC/AHA Guidelines: A Systematic Review and Meta-Analysis

Author

Ciocca, Nicola, primary, Lu, Henri, additional, Tzimas, Georgios, additional, Muller, Olivier, additional, Masi, Ambra, additional, Maurizi, Niccolò, additional, Skalidis, Ioannis, additional, Gissler, Mark Colin, additional, Monney, Pierre, additional, Schwitter, Juerg, additional, Ge, Yin, additional, and Antiochos, Panagiotis, additional

Published
2024
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19. Comparative Prognostic Utility of Coronary CT and Invasive Angiography

Author

Leipsic, Jonathon, primary, Ben Zekry, Sagit, additional, Tzimas, Georgios, additional, Broderick, Samuel, additional, Mancini, G.B. John, additional, Hague, Cameron J., additional, Budoff, Matt J., additional, Rockhold, Frank W., additional, Chaitman, Bernard R., additional, Kirby, Ruth, additional, Stone, Gregg W., additional, Ali, Ziad A., additional, Min, James K., additional, Hochman, Judith S., additional, Maron, David J., additional, and Reynolds, Harmony R., additional

Published
2024
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20. Prevention of esophageal lesions during atrial fibrillation catheter ablation using esophageal temperature monitoring: A systematic review and meta‐analysis

Author

Salihu, Adil, primary, Lu, Henri, additional, Maurizi, Niccolo, additional, Tzimas, Georgios, additional, Herrera Siklody, Claudia, additional, Le Bloa, Mathieu, additional, Domenichini, Giulia, additional, Teres, Cheryl, additional, Hugelshofer, Sarah, additional, Monney, Pierre, additional, Pruvot, Etienne, additional, Muller, Olivier, additional, Antiochos, Panagiotis, additional, and Pascale, Patrizio, additional

Published
2024
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21. Association of Tube Voltage With Plaque Composition on Coronary CT Angiography: Results From PARADIGM Registry

Author

Takagi, Hidenobu, Leipsic, Jonathon A., Indraratna, Praveen, Gulsin, Gaurav, Khasanova, Elina, Tzimas, Georgios, Lin, Fay Y., Shaw, Leslee J., Lee, Sang-Eun, Andreini, Daniele, Al-Mallah, Mouaz H., Budoff, Matthew J., Cademartiri, Filippo, Chinnaiyan, Kavitha, Choi, Jung Hyun, Conte, Edoardo, Marques, Hugo, de Araújo Gonçalves, Pedro, Gottlieb, Ilan, Hadamitzky, Martin, Maffei, Erica, Pontone, Gianluca, Shin, Sanghoon, Kim, Yong-Jin, Lee, Byoung Kwon, Chun, Eun Ju, Sung, Ji Min, Virmani, Renu, Samady, Habib, Stone, Peter H., Berman, Daniel S., Narula, Jagat, Bax, Jeroen J., and Chang, Hyuk-Jae

Published
2021
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22. Evaluation of the 2023 Duke-International Society of Cardiovascular Infectious Diseases Criteria in a Multicenter Cohort of Patients With Suspected Infective Endocarditis

Author

Papadimitriou-Olivgeris, Matthaios; https://orcid.org/0000-0003-0565-5105, Monney, Pierre; https://orcid.org/0000-0002-3083-7333, Frank, Michelle, Tzimas, Georgios, Tozzi, Piergiorgio; https://orcid.org/0000-0002-7648-2531, Kirsch, Matthias; https://orcid.org/0000-0002-9213-7578, Van Hemelrijck, Mathias; https://orcid.org/0000-0002-0191-757X, Bauernschmitt, Robert, Epprecht, Jana; https://orcid.org/0000-0003-3277-7044, Guery, Benoit, Hasse, Barbara; https://orcid.org/0000-0001-7196-3734, Papadimitriou-Olivgeris, Matthaios; https://orcid.org/0000-0003-0565-5105, Monney, Pierre; https://orcid.org/0000-0002-3083-7333, Frank, Michelle, Tzimas, Georgios, Tozzi, Piergiorgio; https://orcid.org/0000-0002-7648-2531, Kirsch, Matthias; https://orcid.org/0000-0002-9213-7578, Van Hemelrijck, Mathias; https://orcid.org/0000-0002-0191-757X, Bauernschmitt, Robert, Epprecht, Jana; https://orcid.org/0000-0003-3277-7044, Guery, Benoit, and Hasse, Barbara; https://orcid.org/0000-0001-7196-3734

Abstract

Background Since publication of Duke criteria for infective endocarditis (IE) diagnosis, several modifications have been proposed. We aimed to evaluate the diagnostic performance of the Duke-ISCVID (International Society of Cardiovascular Infectious Diseases) 2023 criteria compared to prior versions from 2000 (Duke-Li 2000) and 2015 (Duke-ESC [European Society for Cardiology] 2015). Methods This study was conducted at 2 university hospitals between 2014 and 2022 among patients with suspected IE. A case was classified as IE (final IE diagnosis) by the Endocarditis Team. Sensitivity for each version of the Duke criteria was calculated among patients with confirmed IE based on pathological, surgical, and microbiological data. Specificity for each version of the Duke criteria was calculated among patients with suspected IE for whom IE diagnosis was ruled out. Results In total, 2132 episodes with suspected IE were included, of which 1101 (52%) had final IE diagnosis. Definite IE by pathologic criteria was found in 285 (13%), 285 (13%), and 345 (16%) patients using the Duke-Li 2000, Duke-ESC 2015, or the Duke-ISCVID 2023 criteria, respectively. IE was excluded by histopathology in 25 (1%) patients. The Duke-ISCVID 2023 clinical criteria showed a higher sensitivity (84%) compared to previous versions (70%). However, specificity of the new clinical criteria was lower (60%) compared to previous versions (74%). Conclusions The Duke-ISCVID 2023 criteria led to an increase in sensitivity compared to previous versions. Further studies are needed to evaluate items that could increase sensitivity by reducing the number of IE patients misclassified as possible, but without having detrimental effect on specificity of Duke criteria.

Published
2024

23. Evaluation of the 2023 Duke-ISCVID and 2023 Duke-ESC clinical criteria for the diagnosis of infective endocarditis in a multicenter cohort of patients with Staphylococcus aureus bacteremia

Author

Papadimitriou-Olivgeris, Matthaios; https://orcid.org/0000-0003-0565-5105, Monney, Pierre, Frank, Michelle, Tzimas, Georgios, Tozzi, Piergiorgio; https://orcid.org/0000-0002-7648-2531, Kirsch, Matthias; https://orcid.org/0000-0002-9213-7578, Van Hemelrijck, Mathias; https://orcid.org/0000-0002-0191-757X, Bauernschmitt, Robert, Epprecht, Jana; https://orcid.org/0000-0003-3277-7044, Guery, Benoit, Hasse, Barbara; https://orcid.org/0000-0001-7196-3734, Papadimitriou-Olivgeris, Matthaios; https://orcid.org/0000-0003-0565-5105, Monney, Pierre, Frank, Michelle, Tzimas, Georgios, Tozzi, Piergiorgio; https://orcid.org/0000-0002-7648-2531, Kirsch, Matthias; https://orcid.org/0000-0002-9213-7578, Van Hemelrijck, Mathias; https://orcid.org/0000-0002-0191-757X, Bauernschmitt, Robert, Epprecht, Jana; https://orcid.org/0000-0003-3277-7044, Guery, Benoit, and Hasse, Barbara; https://orcid.org/0000-0001-7196-3734

Abstract

BACKGROUND The Duke criteria for infective endocarditis (IE) diagnosis underwent revisions in 2023 by the European Society of Cardiology (ESC) and the International Society for Cardiovascular Infectious Diseases (ISCVID). This study aims to assess the diagnostic accuracy of these criteria, focusing on patients with Staphylococcus aureus bacteremia (SAB). METHODS This Swiss multicenter study conducted between 2014 and 2023 pooled data from three cohorts. It evaluated the performance of each iteration of the Duke criteria by assessing the degree of concordance between definite S. aureus IE (SAIE) and the diagnoses made by the Endocarditis Team (2018-23) or IE expert clinicians (2014-17). RESULTS Among 1344 SAB episodes analyzed, 486 (36%) were identified as cases of SAIE. The 2023 Duke-ISCVID and 2023 Duke-ESC criteria demonstrated improved sensitivity for SAIE diagnosis (81% and 82%, respectively) compared to the 2015 Duke-ESC criteria (75%). However, the new criteria exhibited reduced specificity for SAIE (96% for both) compared to the 2015 criteria (99%). Spondylodiscitis was more prevalent among patients with SAIE compared to those with SAB alone (10% versus 7%, P 0.026). However, when patients meeting the minor 2015 Duke-ESC vascular criterion were excluded, the incidence of spondylodiscitis was similar between SAIE and SAB patients (6% versus 5%, P 0.461). CONCLUSIONS The 2023 Duke-ISCVID and 2023 Duke-ESC clinical criteria, show improved sensitivity for SAIE diagnosis compared to 2015 Duke-ESC criteria. However, this increase in sensitivity comes at the expense of reduced specificity. Future research should aim at evaluating the impact of each component introduced within these criteria.

Published
2024

24. Evaluation of the HANDOC Score and the 2023 International Society of Cardiovascular Infectious Diseases and European Society of Cardiology Duke Clinical Criteria for the Diagnosis of Infective Endocarditis Among Patients With Streptococcal Bacteremia.

Author

Fourré, Nicolas, Zimmermann, Virgile, Senn, Laurence, Monney, Pierre, Tzimas, Georgios, Caruana, Giorgia, Tozzi, Piergiorgio, Kirsch, Matthias, Guery, Benoit, and Papadimitriou-Olivgeris, Matthaios

Subjects
RISK assessment, BLOOD, ACADEMIC medical centers, MICROBIAL sensitivity tests, BACTEREMIA, BLOODBORNE infections, CATHETER-related infections, INFECTIVE endocarditis, RETROSPECTIVE studies, DESCRIPTIVE statistics, LONGITUDINAL method, CELL culture, MEDICAL records, ACQUISITION of data, ELECTRONIC health records, SEPSIS, STREPTOCOCCAL diseases, DATA analysis software, CONFIDENCE intervals, ECHOCARDIOGRAPHY, SENSITIVITY & specificity (Statistics), DISEASE risk factors, DISEASE complications
Abstract

Background Streptococci are a common cause of infective endocarditis (IE). We aimed to evaluate the performance of the HANDOC score to identify patients at high risk for IE and the Duke clinical criteria of the European Society of Cardiology (ESC; 2015 and 2023 versions) and the 2023 version from the International Society of Cardiovascular Infectious Diseases (ISCVID) in diagnosing IE among patients with streptococcal bacteremia. Methods This retrospective study included adult patients with streptococcal bacteremia hospitalized at Lausanne University Hospital. Episodes were classified as IE by the Endocarditis Team. A HANDOC score >2 classified patients as high risk for IE. Results Among 851 episodes with streptococcal bacteremia, IE was diagnosed in 171 episodes (20%). Among 607 episodes with non-β-hemolytic streptococci, 213 (35%) had HANDOC scores >2 points; 132 (22%) had IE. The sensitivity of the HANDOC score to identify episodes at high risk for IE was 95% (95% confidence interval [CI], 90%–98%), the specificity 82% (95% CI, 78%–85%), and the negative predictive value (NPV) 98% (95% CI, 96%–99%). 2015 Duke-ESC, 2023 Duke-ISCVID, and 2023 Duke-ESC clinical criteria classified 114 (13%), 145 (17%), and 126 (15%) episodes as definite IE, respectively. Sensitivity (95% CI) for the 2015 Duke-ESC, 2023 Duke-ISCVID, and 2023 Duke-ESC clinical criteria was calculated at 65% (57%–72%), 81% (74%–86%), and 73% (65%–79%), respectively, with specificity (95% CI) at 100% (98%–100%), 99% (98%–100%), and 99% (98%–100%), respectively. Conclusions The HANDOC score showed an excellent NPV to identify episodes at high risk for IE. Among the different versions of the Duke criteria, the 2023 Duke-ISCVID version fared better for the diagnosis of IE among streptococcal bacteremia. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Evaluation of the 2023 Duke-International Society of Cardiovascular Infectious Diseases Criteria in a Multicenter Cohort of Patients With Suspected Infective Endocarditis

Author

Papadimitriou-Olivgeris, Matthaios, primary, Monney, Pierre, additional, Frank, Michelle, additional, Tzimas, Georgios, additional, Tozzi, Piergiorgio, additional, Kirsch, Matthias, additional, Van Hemelrijck, Mathias, additional, Bauernschmitt, Robert, additional, Epprecht, Jana, additional, Guery, Benoit, additional, and Hasse, Barbara, additional

Published
2024
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29. Transcaval versus Supra-Aortic Vascular Accesses for Transcatheter Aortic Valve Replacement: A Systematic Review with Meta-Analysis

Author

Antiochos, Panagiotis, primary, Kirsch, Matthias, additional, Monney, Pierre, additional, Tzimas, Georgios, additional, Meier, David, additional, Fournier, Stephane, additional, Ferlay, Clémence, additional, Nowacka, Anna, additional, Rancati, Valentina, additional, Abellan, Christophe, additional, Skalidis, Ioannis, additional, Muller, Olivier, additional, and Lu, Henri, additional

Published
2024
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30. Evaluation of the 2023 Duke-ISCVID and 2023 Duke-ESC Clinical Criteria for the Diagnosis of Infective Endocarditis in a Multicenter Cohort of Patients With Staphylococcus aureus Bacteremia

Author

Papadimitriou-Olivgeris, Matthaios, primary, Monney, Pierre, additional, Frank, Michelle, additional, Tzimas, Georgios, additional, Tozzi, Piergiorgio, additional, Kirsch, Matthias, additional, Van Hemelrijck, Mathias, additional, Bauernschmitt, Robert, additional, Epprecht, Jana, additional, Guery, Benoit, additional, and Hasse, Barbara, additional

Published
2024
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32. Cardiologie: ce qui a changé en 2023

Author

Salihu, Adil, primary, Meier, David, additional, Kilani, Nadia, additional, Burdet, Odile, additional, Tzimas, Georgios, additional, Antiochos, Panagiotis, additional, Masi, Ambra, additional, Teres, Cheryl, additional, Ascione, Ciro, additional, Rosset, Sabina, additional, Daux, Aurélien, additional, Domenichini, Giulia, additional, Ladouceur, Magalie, additional, Yerly, Patrick, additional, Schwitter, Juerg, additional, Monney, Pierre, additional, Rutz, Tobias, additional, Bouchardy, Judith, additional, Pruvot, Etienne, additional, Muller, Olivier, additional, and Fournier, Stephane, additional

Published
2024
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36. Energy Loss Index and Dimensionless Index Outperform Direct Valve Planimetry in Low-Gradient Aortic Stenosis.

Author

Hugelshofer, Sarah, de Brito, Diana, Antiochos, Panagiotis, Tzimas, Georgios, Rotzinger, David C., Auberson, Denise, Vella, Agnese, Fournier, Stephane, Kirsch, Matthias, Muller, Olivier, and Monney, Pierre

Subjects
AORTIC stenosis, ENERGY dissipation, TRANSESOPHAGEAL echocardiography, VALVES, RECEIVER operating characteristic curves
Abstract

Background/Objectives: Among patients with suspected severe aortic stenosis (AS), discordance between effective orifice area (EOA) and transvalvular gradients is frequent and requires a multiparametric workup including flow assessment and calcium-scoring to confirm true severe AS. The aim of this study was to assess direct planimetry, energy loss index (Eli) and dimensionless index (DI) as stand-alone parameters to identify non-severe AS in discordant cases. Methods: In this prospective cohort study, we included consecutive AS patients > 70 years with EOA < 1.0 cm2 referred for valve replacement between 2014 and 2017. AS severity was retrospectively reassessed using the multiparametric work-up recommended in the 2021 ESC/EACTS guidelines. DI and ELi were calculated, and valve area was measured by direct planimetry on transesophageal echocardiography. Results: A total of 101 patients (mean age 82 y; 57% male) were included. Discordance between EOA and gradients was observed in 46% and non-severe AS found in 24% despite an EOA < 1 cm2. Valve planimetry performed poorly, with an area under the ROC curve (AUC) of 0.64. At a cut-off value of >0.82 cm2, sensitivity and specificity to identify non-severe AS were 67 and 66%, respectively. DI and ELi showed a higher diagnostic accuracy, with an AUC of 0.77 and 0.76, respectively. Cut-off values of >0.24 and >0.6 cm2/m2 identified non-severe AS, with a high specificity of 79% and 91%, respectively. Conclusions: Almost one in four patients with EOA < 1 cm2 had non-severe AS according to guideline-recommended multiparametric assessment. Direct valve planimetry revealed poor diagnostic accuracy and should be interpreted with caution. Usual prognostic cut-off values for DI > 0.24 and ELI > 0.6 cm2/m2 identified non-severe AS with high specificity and should therefore be included in the assessment of low-gradient AS. [ABSTRACT FROM AUTHOR]

Published
2024
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37. European Society of Cardiology guidelines and 1 year outcomes of acute heart failure treatment in Central Asia and Europe

Author

Abdurashidova, Tamila, primary, Müller, Martin, additional, Schukraft, Sara, additional, Soborun, Nisha, additional, Pitta‐Gros, Barbara, additional, Kikoïne, John, additional, Lu, Henri, additional, Chazymova, Zalina, additional, Dzhorupbekova, Kanzaada, additional, Beishenkulov, Medet, additional, Tzimas, Georgios, additional, Kirsch, Matthias, additional, Vollenweider, Peter, additional, Mean, Marie, additional, Monney, Pierre, additional, and Hullin, Roger, additional

Published
2023
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38. Artificial Intelligence–based Coronary Stenosis Quantification at Coronary CT Angiography versus Quantitative Coronary Angiography

Author

Dundas, James, primary, Leipsic, Jonathon A., additional, Sellers, Stephanie, additional, Blanke, Philipp, additional, Miranda, Patricia, additional, Ng, Nicholas, additional, Mullen, Sarah, additional, Meier, David, additional, Akodad, Mariama, additional, Sathananthan, Janarthanan, additional, Collet, Carlos, additional, de Bruyne, Bernard, additional, Muller, Olivier, additional, and Tzimas, Georgios, additional

Published
2023
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39. Redo-TAVI with SAPIEN 3 in SAPIEN XT or SAPIEN 3 &ndash; impact of pre- and post-dilatation on final THV expansion

Author

Meier, David, primary, Landes, Uri, additional, Sondergaard, Lars, additional, De Backer, Ole, additional, Lutter, Georg, additional, Puehler, Thomas, additional, Akodad, Mariama, additional, Tzimas, Georgios, additional, Blanke, Philipp, additional, Payne, Geoffrey W., additional, Lai, Althea, additional, Gill, Hacina, additional, Wood, David A., additional, Webb, John G., additional, Sellers, Stephanie L., additional, and Sathananthan, Janarthanan, additional

Published
2023
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40. Case Report: Stretching the limits—late valvuloplasty for THV dysfunction following redo mitral valve-in-valve implantation

Author

Meier, David, primary, Tzimas, Georgios, additional, Akodad, Mariama, additional, Husain, Ali, additional, Dundas, James, additional, Jelisejevas, Julius, additional, Cheung, Anson, additional, Sellers, Stephanie L., additional, Leipsic, Jonathon A., additional, Blanke, Philipp, additional, Wood, David A., additional, Sathananthan, Janarthanan, additional, and Webb, John G., additional

Published
2023
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41. Impact of Coronary CT Angiography–derived Fractional Flow Reserve on Downstream Management and Clinical Outcomes in Individuals with and without Diabetes

Author

Gulsin, Gaurav S., primary, Tzimas, Georgios, additional, Holmes, Kenneth-Royce, additional, Takagi, Hidenobu, additional, Sellers, Stephanie L., additional, Blanke, Philipp, additional, Koweek, Lynne M. H., additional, Nørgaard, Bjarne L., additional, Jensen, Jesper, additional, Rabbat, Mark G., additional, Pontone, Gianluca, additional, Fairbairn, Timothy A., additional, Chinnaiyan, Kavitha M., additional, Douglas, Pamela S., additional, Huey, Whitney, additional, Matsuo, Hitoshi, additional, Sand, Niels P. R., additional, Nieman, Koen, additional, Bax, Jeroen J., additional, Amano, Tetsuya, additional, Kawasaki, Tomohiro, additional, Akasaka, Takashi, additional, Rogers, Campbell, additional, Berman, Daniel S., additional, Patel, Manesh R., additional, De Bruyne, Bernard, additional, Mullen, Sarah, additional, and Leipsic, Jonathon A., additional

Published
2023
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45. Valve-in-valve transcatheter mitral valve replacement: a large first-in-man 13-year experience

Author

Akodad, Mariama, primary, Trpkov, Cvet, additional, Cheung, Anson, additional, Ye, Jian, additional, Chatfield, Andrew G., additional, Alosail, Abdulmajeed, additional, Besola, Laura, additional, Yu, Maggie, additional, Leipsic, Jonathon A., additional, Lounes, Youcef, additional, Meier, David, additional, Yang, Cathevine, additional, Nestelberger, Thomas, additional, Tzimas, Georgios, additional, Sathananthan, Janarthanan, additional, Wood, David A., additional, Moss, Rob R., additional, Blanke, Philipp, additional, Sathananthan, Gnalini, additional, and Webb, John G., additional

Published
2023
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46. European Society of Cardiology guidelines and 1 year outcomes of acute heart failure treatment in Central Asia and Europe.

Author

Abdurashidova, Tamila, Müller, Martin, Schukraft, Sara, Soborun, Nisha, Pitta‐Gros, Barbara, Kikoïne, John, Lu, Henri, Chazymova, Zalina, Dzhorupbekova, Kanzaada, Beishenkulov, Medet, Tzimas, Georgios, Kirsch, Matthias, Vollenweider, Peter, Mean, Marie, Monney, Pierre, and Hullin, Roger

Subjects
HEART failure, RHEUMATIC heart disease, CHRONIC obstructive pulmonary disease, TREATMENT failure, ATRIAL flutter
Abstract

Aims: Outcomes reported for patients with hospitalization for acute heart failure (AHF) treatment vary worldwide. Ethnicity‐associated characteristics may explain this observation. This observational study compares characteristics and 1‐year outcomes of Kyrgyz and Swiss AHF patients against the background of European Society of Cardiology guidelines‐based cardiovascular care established in both countries. Methods and results: The primary endpoint was 1 year all‐cause mortality (ACM); the secondary endpoint was 1 year ACM or HF‐related rehospitalization. A total of 538 Kyrgyz and 537 Swiss AHF patients were included. Kyrgyz patients were younger (64.0 vs. 83.0 years, P < 0.001); ischaemic or rheumatic heart disease and chronic obstructive pulmonary disease were more prevalent (always P < 0.001). In Swiss patients, smoking, dyslipidaemia, hypertension, and atrial flutter/fibrillation were more frequent (always P ≤ 0.035); moreover, left ventricular ejection fraction (LVEF) was higher (47% vs. 36%; P < 0.001), and >mild aortic stenosis was more prevalent (P < 0.001). Other valvular pathologies were more prevalent in Kyrgyz patients (P < 0.001). At discharge, more Swiss patients were on vasodilatory treatment (P < 0.006), while mineralocorticoid receptor antagonists (P = 0.001), beta‐blockers (P = 0.001), or loop diuretics (P < 0.001) were less often prescribed. In Kyrgyz patients, unadjusted odds for the primary and secondary endpoints were lower [odds ratio (OR) 0.68, 95% confidence interval (CI): 0.51–0.90, P = 0.008; OR 0.72, 95% CI: 0.56–0.91, P = 0.006, respectively]. After adjustment for age and LVEF, no difference remained (primary endpoint: OR 1.03, 95% CI: 0.71–1.49, P = 0.894; secondary endpoint: OR 0.82, 95% CI: 0.60–1.12, P = 0.206). Conclusions: On the background of identical guidelines, age‐ and LVEF‐adjusted outcomes were not different between Central Asian and Western European AHF patients despite of large ethnical disparity. [ABSTRACT FROM AUTHOR]

Published
2024
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