1. [The application of panel CytoDiff for monitoring of effectiveness of antiviral therapy in HIV-infected patients].
- Author
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Kviatkovskaia SV, Sukhacheva EA, Reshetnikov IV, Dolgova NV, Tseĭlikman OB, and Tseĭlikman VÉ
- Subjects
- Antiretroviral Therapy, Highly Active methods, Female, Humans, Leukocyte Count methods, Leukocytes virology, Male, Viral Load, Flow Cytometry methods, HIV Infections blood, HIV Infections drug therapy, Leukocytes metabolism, Monitoring, Physiologic methods, Reagent Kits, Diagnostic
- Abstract
The study of HIV-infected patients using new five-color panel CytoDiff for flow cytofluorometry revealed the imbalance in subpopulations of leukocytes. The manifestations consisted in significant decrease of total amount of lymphocytes and also CD16+ lymphocytes. B-lymphocytes and eosinocytes with synchronous increase of level of CD16+ monocytes, neutrophils and immature B-lymphocytes. After application to patients of highly active anti-retroviral therapy occurred decrease of viral load under synchronous increase of total level of lymphocytes, CD16+ lymphocytes, B-lymphocytes and also decrease of amount of CD16+ monocytes, neutrophils and immature B-lymphocytes.
- Published
- 2014