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[The application of panel CytoDiff for monitoring of effectiveness of antiviral therapy in HIV-infected patients].

Authors :
Kviatkovskaia SV
Sukhacheva EA
Reshetnikov IV
Dolgova NV
Tseĭlikman OB
Tseĭlikman VÉ
Source :
Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2014 Jul; Vol. 59 (7), pp. 58-61.
Publication Year :
2014

Abstract

The study of HIV-infected patients using new five-color panel CytoDiff for flow cytofluorometry revealed the imbalance in subpopulations of leukocytes. The manifestations consisted in significant decrease of total amount of lymphocytes and also CD16+ lymphocytes. B-lymphocytes and eosinocytes with synchronous increase of level of CD16+ monocytes, neutrophils and immature B-lymphocytes. After application to patients of highly active anti-retroviral therapy occurred decrease of viral load under synchronous increase of total level of lymphocytes, CD16+ lymphocytes, B-lymphocytes and also decrease of amount of CD16+ monocytes, neutrophils and immature B-lymphocytes.

Details

Language :
Russian
ISSN :
0869-2084
Volume :
59
Issue :
7
Database :
MEDLINE
Journal :
Klinicheskaia laboratornaia diagnostika
Publication Type :
Academic Journal
Accession number :
25346991