1. Coronapp : A web application to annotate and monitor SARS‐CoV‐2 mutations
- Author
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Daniele Mercatelli, Federico M. Giorgi, Luca Triboli, Forest Ray, Eleonora Fornasari, Mercatelli D., Triboli L., Fornasari E., Ray F., and Giorgi F.M.
- Subjects
2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,Computer science ,Short Communication ,Genomic data ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Population ,Short Communications ,Genome, Viral ,Computational biology ,SARS‐CoV‐2 ,03 medical and health sciences ,Annotation ,0302 clinical medicine ,COVID‐19 ,Virology ,Humans ,Web application ,genetics ,Amino Acid Sequence ,030212 general & internal medicine ,education ,education.field_of_study ,SARS-CoV-2 ,business.industry ,COVID-19 ,Genomics ,web application ,mutations ,Infectious Diseases ,030211 gastroenterology & hepatology ,genetic ,mutation ,business - Abstract
The avalanche of genomic data generated from the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) virus requires the development of tools to detect and monitor its mutations across the world. Here, we present a webtool, coronapp, dedicated to easily processing user‐provided SARS‐CoV‐2 genomic sequences and visualizing the current worldwide status of SARS‐CoV‐2 mutations. The webtool allows users to highlight mutations and categorize them by frequency, country, genomic location and effect on protein sequences, and to monitor their presence in the population over time. The tool is available at http://giorgilab.unibo.it/coronannotator/ for the annotation of user‐provided sequences. The full code is freely shared at https://github.com/federicogiorgi/giorgilab/tree/master/coronannotator.
- Published
- 2020
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