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INTRODUCTION: Estimating treatment effects as time savings in disease progression may be more easily interpretable than assessing the absolute difference or a percentage reduction. In this study, we investigate the statistical considerations of the existing method for estimating time savings and propose alternative complementary methods. METHODS: We propose five alternative methods to estimate the time savings from different perspectives. These methods are applied to simulated clinical trial data that mimic or modify the Clinical Dementia Rating Sum of Boxes progression trajectories observed in the Clarity AD lecanemab trial. RESULTS: Our study demonstrates that the proposed methods can generate more precise estimates by considering two crucial factors: (1) the absolute difference between treatment arms, and (2) the observed progression rate in the treatment arm. DISCUSSION: Quantifying treatment effects as time savings in disease progression offers distinct advantages. To provide comprehensive estimations, it is important to use various methods. Highlights: We explore the statistical considerations of the current method for estimating time savings.We proposed alternative methods that provide time savings estimations based on the observed absolute differences.By using various methods, a more comprehensive estimation of time savings can be achieved. [ABSTRACT FROM AUTHOR]

This study investigates the association between adoption of pay-as-you-go (PAYG) liquefied petroleum gas (LPG), an emerging alternative to full cylinder LPG, and women's economic empowerment in an informal settlement in Nairobi, Kenya. From December 2021-January 2022, 293 customers of a PAYG LPG company (PayGo Energy) were surveyed on their cooking patterns, financial savings and shifts in dietary behaviors following uptake of the technology. Among PayGo Energy customers that previously cooked only with polluting fuels (N = 78; 27 % of customers), daily cooking time was reduced by an average of 42 min/day; 82 % of PayGo Energy customers that previously cooked with full cylinder LPG (N = 216; 73 % of customers) also decreased their cooking time (average of 20 min/day) when switching to PAYG LPG. The majority (58 %; N = 70) of female household heads took on additional employment after switching to PAYG LPG, compared with 36 % (N = 55) of females living in male-headed households. Among female household heads, the proportion of informal sector workers earning wages on an irregular (71 %) or daily basis (61 %) that took on new income-generating activities after transitioning to PAYG LPG was over 20 % higher than those earning monthly salaries (39 %). Increased dietary diversity and consumption of protein-rich foods (legumes, meat, fish) from cooking with PAYG LPG was reported by 15 % of female household heads compared with 5 % of those living in male-headed households. While nearly three-quarters (73 %) of PayGo Energy customers would recommend the service to others because of the added convenience it provides, only one-third (29 %) reported associated health benefits as a key reason for promoting use of PAYG LPG to community members. Female household heads were more likely than non-household heads to be socioeconomically empowered when adopting PAYG LPG, illustrating that women's agency may influence the associated benefits of clean energy transitions. Nonetheless, the time savings reported by nearly all women who switched to PAYG LPG for cooking suggests that promoting the increased convenience of cooking with PAYG LPG may be useful for accelerating its adoption..

This study optimizes the sustainable implementation of light wood-framed buildings in the Nordic region using multi-criteria decision-making. Integrating prefabrication, transportation logistics, and multi-criteria decision-making (MCDM) methods enhances cost efficiency, time savings, and quality assurance. Significant international and local impact promotes sustainable construction practices. Strong promotion fosters industry-wide adoption. The presented framework enables stakeholders to make informed decisions, enhancing the efficiency and effectiveness of building implementation processes and fostering sustainable development in the construction industry. [ABSTRACT FROM AUTHOR]

Patient-generated device data play an important role in diabetes management. However, acquiring these data remains a challenge. This project aimed to understand whether implementing dedicated "Technology Navigator" (TN) personnel at a large academic diabetes clinic could facilitate access to device data without increasing work for clinic staff. A sample of visits pre- and post-TN implementation (n = 173) showed a 22% (41% vs. 19%) increase in patients who successfully shared their data from home before their visit and a 52% (67% vs. 15%) increase in visits where data were available to the provider for review before the appointment, whereas billing claims for continuous glucose monitor interpretation increased by 86% during the same period. Time analysis suggests that home uploads could save up to 747 h in medical assistant labor annually. Incorporating a TN may improve data availability, decrease time spent on nonbillable activities, and support data interpretation and billing. [ABSTRACT FROM AUTHOR]

Objective:The aim of this study was to evaluate efficiency of time use for radiologists and operational costs of automated breast ultrasound (ABUS) versus handheld breast ultrasound (HHUS).Materials and Methods:This study was approved by the Institutional Review Board, and informed consent was waived. One hundred and fifty-three patients, aged 21–81 years, underwent both ABUS and HHUS. The time required for the ABUS scanning and radiologist interpretation and the combined scanning and interpretation time for HHUS were recorded for screening and diagnostic exams. One-Way ANOVA test was used to compare the methods, and Cohen Kappa statistics were used to achieve the agreement levels. Finally, the cost of the methods and return of interest were compared by completing a cost analysis.Results:The overall mean ± standard deviation examination time required for ABUS examination was 676.2±145.42 seconds while mean scan time performed by radiographers was 411.76±67.79 seconds, and the mean radiologist time was 234.01±81.88 seconds. The overall mean examination time required for HHUS was 452.52±171.26 seconds, and the mean scan time and radiologist time were 419.62±143.24 seconds. The reduced time translated into savings of 7.369 TL/month, and savings of 22% in operational costs was achieved with ABUS.Conclusion:The radiologist’s time was reduced with ABUS in both screening and diagnostic scenarios. Although a second-look HHUS is required for diagnostic cases, ABUS still saves radiologists time by enabling a focused approach instead of a complete evaluation of both breasts. Thus, ABUS appears to save both medical staff time and operational costs.

Simple Summary: Auto contouring driven by artificial intelligence can improve the workflow of radiotherapy by accelerating the contouring process. However, quality assurance of artificial intelligence-based tools is necessary for ensuring safety and efficacy in a clinical practice. In this study investigated the geometric accuracy of structural contours created by a commercial software for autocontouring based on artificial intelligence using well established metrics. In particular, the impact on the radiotherapy treatment plan quality from the adoption of artificial intelligence generated contours was investigated. Our results show that the combination of automatically generated contours and careful review by a clinical radiation oncologist results in time saving without affecting the quality of treatment plan. In conclusion, after quality checks that involve both geometric accuracy as well as dosimetric impact, contouring based on AI can be safely adopted in clinical practice. Purpose: When autocontouring based on artificial intelligence (AI) is used in the radiotherapy (RT) workflow, the contours are reviewed and eventually adjusted by a radiation oncologist before an RT treatment plan is generated, with the purpose of improving dosimetry and reducing both interobserver variability and time for contouring. The purpose of this study was to evaluate the results of application of a commercial AI-based autocontouring for RT, assessing both geometric accuracies and the influence on optimized dose from automatically generated contours after review by human operator. Materials and Methods: A commercial autocontouring system was applied to a retrospective database of 40 patients, of which 20 were treated with radiotherapy for prostate cancer (PCa) and 20 for head and neck cancer (HNC). Contours resulting from AI were compared against AI contours reviewed by human operator and human-only contours using Dice similarity coefficient (DSC), Hausdorff distance (HD), and relative volume difference (RVD). Dosimetric indices such as Dmean, D0.03cc, and normalized plan quality metrics were used to compare dose distributions from RT plans generated from structure sets contoured by humans assisted by AI against plans from manual contours. The reduction in contouring time obtained by using automated tools was also assessed. A Wilcoxon rank sum test was computed to assess the significance of differences. Interobserver variability of the comparison of manual vs. AI-assisted contours was also assessed among two radiation oncologists for PCa. Results: For PCa, AI-assisted segmentation showed good agreement with expert radiation oncologist structures with average DSC among patients ≥ 0.7 for all structures, and minimal radiation oncology adjustment of structures (DSC of adjusted versus AI structures ≥ 0.91). For HNC, results of comparison between manual and AI contouring varied considerably e.g., 0.77 for oral cavity and 0.11–0.13 for brachial plexus, but again, adjustment was generally minimal (DSC of adjusted against AI contours 0.97 for oral cavity, 0.92–0.93 for brachial plexus). The difference in dose for the target and organs at risk were not statistically significant between human and AI-assisted, with the only exceptions of D0.03cc to the anal canal and Dmean to the brachial plexus. The observed average differences in plan quality for PCa and HNC cases were 8% and 6.7%, respectively. The dose parameter changes due to interobserver variability in PCa were small, with the exception of the anal canal, where large dose variations were observed. The reduction in time required for contouring was 72% for PCa and 84% for HNC. Conclusions: When an autocontouring system is used in combination with human review, the time of the RT workflow is significantly reduced without affecting dose distribution and plan quality. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was to evaluate efficiency of time use for radiologists and operational costs of automated breast ultrasound (ABUS) versus handheld breast ultrasound (HHUS). Materials and Methods: This study was approved by the Institutional Review Board, and informed consent was waived. One hundred and fifty-three patients, aged 21-81 years, underwent both ABUS and HHUS. The time required for the ABUS scanning and radiologist interpretation and the combined scanning and interpretation time for HHUS were recorded for screening and diagnostic exams. One-Way ANOVA test was used to compare the methods, and Cohen Kappa statistics were used to achieve the agreement levels. Finally, the cost of the methods and return of interest were compared by completing a cost analysis. Results: The overall mean ± standard deviation examination time required for ABUS examination was 676.2 ± 145.42 seconds while mean scan time performed by radiographers was 411.76 ± 67.79 seconds, and the mean radiologist time was 234.01 ± 81.88 seconds. The overall mean examination time required for HHUS was 452.52 ± 171.26 seconds, and the mean scan time and radiologist time were 419.62 ± 143.24 seconds. The reduced time translated into savings of 7.369 TL/month, and savings of 22% in operational costs was achieved with ABUS. Conclusion: The radiologist's time was reduced with ABUS in both screening and diagnostic scenarios. Although a second-look HHUS is required for diagnostic cases, ABUS still saves radiologists time by enabling a focused approach instead of a complete evaluation of both breasts. Thus, ABUS appears to save both medical staff time and operational costs. [ABSTRACT FROM AUTHOR]

Factory accidents have far-reaching consequences, impacting not only the workers but also the reputation and financial stability of organizations, making management of safety risks crucial. When work-related hazards are effectively managed, the probability of accidents within that plant can be reduced to zero, which is the embedded philosophy of every organization's safety policy. Plant inspections include non-destructive methodologies like thermography and ultrasonic thickness inspections of stacks, tanks and piping as part of process safety management and energy efficiency assurance. Leveraging drone technology for inspecting plant areas that involve heights offers significant advantages. By eliminating the need for workers to physically engage in work at height activities without compromising on plantrelated data, organizations can ensure impeccable safety metrics, and reinforce a positive safety culture. This paper presents three practical case studies implemented in different process industries and provides a solid basis for feasibility proposals and studies. Safety risks were eliminated 100% with collateral benefits in the form of significant savings in time (up to 97%), improvement in quality of inspection (-80%) and substantial (up to -90%) overall costs savings. [ABSTRACT FROM AUTHOR]

Purpose: The purpose of this project was to examine the travel burdens for radiotherapy patients in Nigeria, Tanzania, and South Africa, and to assess the patient-related benefits of hypofractionated radiotherapy (HFRT) for breast and prostate cancer patients in these countries. The outcomes can inform the implementation of the recent Lancet Oncology Commission recommendations on increasing the adoption of HFRT in Sub-Saharan Africa (SSA) to enhance radiotherapy access in the region. Methods: Data were extracted from electronic patient records at the NSIA-LUTH Cancer Center (NLCC) in Lagos, Nigeria and the Inkosi Albert Luthuli Central Hospital (IALCH) in Durban, South Africa, from written records at the University of Nigeria Teaching Hospital (UNTH) Oncology Center in Enugu, Nigeria, and from phone interviews at Ocean Road Cancer Institute (ORCI) in Dar Es Salaam, Tanzania. Google Maps was used to calculate the shortest driving distance between a patient's home address and their respective radiotherapy center. QGIS was used to map the straight-line distances to each center. Descriptive statistics were used to compare transportation costs, time expenditures, and lost wages when using HFRT versus conventionally fractionated radiotherapy (CFRT) for breast and prostate cancer. Results: Patients in Nigeria (n=390) traveled a median distance of 23.1 km to NLCC and 86.7 km to UNTH, patients in Tanzania (n=23) traveled a median distance of 537.0 km to ORCI, and patients in South Africa (n=412) traveled a median distance of 18.0 km to IALCH. Estimated transportation cost savings for breast cancer patients in Lagos and Enugu were 12,895 Naira and 7,369 Naira, respectively and for prostate cancer patients were 25,329 and 14,276 Naira, respectively. Prostate cancer patients in Tanzania saved a median of 137,765 Shillings in transportation costs and 80.0 hours (includes travel, treatment, and wait times). Mean transportation cost savings for patients in South Africa were 4,777 Rand for breast cancer and 9,486 Rand for prostate cancer. Conclusion: Cancer patients in SSA travel considerable distances to access radiotherapy services. HFRT decreases patient-related costs and time expenditures, which may increase radiotherapy access and alleviate the growing burden of cancer in the region. [ABSTRACT FROM AUTHOR]

Critical Chain Project Management (CCPM) has emerged as a notable approach in recent years for improving time management in construction projects. This methodology focuses on optimizing project schedules, and its impact on construction projects has been explored through a review of literature from the past five years. However, a theoretical understanding alone may not be sufficient for promoting the adoption of CCPM in the sector. Therefore, an experimental study was conducted to assess the practical impact of CCPM on shortening the timeline of a construction project. The study involved the use of CPM for the planning phase and CCPM for the execution phase of finishing works (drywalls, carpentry, painting) in three identical blocks of flats. At the completion of the project, an important economy of 36 days (around 20%) was achieved, and the project was completed in 151 days using CCPM compared to the planned 187 days using CPM. The research was limited to finishing works, and further studies are planned to explore the applicability of CCPM to other construction works. It is imperative to establish a continuous collaboration between researchers and practitioners in the construction industry, as research findings should be effectively applied in real-world scenarios. [ABSTRACT FROM AUTHOR]

Even though entirely digitized microscopic tissue sections (whole slide images, WSIs) are increasingly being used in histopathology diagnostics, little data is still available on the effect of this technique on pathologists' reading time. This study aimed to compare the time required to perform the microscopic assessment by pathologists between a conventional workflow (an optical microscope) and digitized WSIs. WSI was used in primary diagnostics at the Laboratory for Pathology Eastern Netherlands for several years (LabPON, Hengelo, The Netherlands). Cases were read either in a traditional workflow, with the pathologist recording the time required for diagnostics and reporting, or entirely digitally. Reading times were extracted from image management system log files, and the digitized workflow was fully integrated into the laboratory information system. The digital workflow saved time in the majority of case categories, with prostate biopsies saving the most (68% time gain). Taking into account case distribution, the digital workflow produced an average gain of 12.3%. Using WSI instead of conventional microscopy significantly reduces pathologists' reading times. Pathologists must work in a fully integrated environment to fully reap the benefits of a digital workflow. [ABSTRACT FROM AUTHOR]

Automatic contouring algorithms may streamline clinical workflows by reducing normal organ-at-risk (OAR) contouring time. Here we report the first comprehensive quantitative and qualitative evaluation, along with time savings assessment for a prototype deep learning segmentation algorithm from Siemens Healthineers. The accuracy of contours generated by the prototype were evaluated quantitatively using the Sorensen-Dice coefficient (Dice), Jaccard index (JC), and Hausdorff distance (Haus). Normal pelvic and head and neck OAR contours were evaluated retrospectively comparing the automatic and manual clinical contours in 100 patient cases. Contouring performance outliers were investigated. To quantify the time savings, a certified medical dosimetrist manually contoured de novo and, separately, edited the generated OARs for 10 head and neck and 10 pelvic patients. The automatic, edited, and manually generated contours were visually evaluated and scored by a practicing radiation oncologist on a scale of 1-4, where a higher score indicated better performance. The quantitative comparison revealed high (> 0.8) Dice and JC performance for relatively large organs such as the lungs, brain, femurs, and kidneys. Smaller elongated structures that had relatively low Dice and JC values tended to have low Hausdorff distances. Poor performing outlier cases revealed common anatomical inconsistencies including overestimation of the bladder and incorrect superior-inferior truncation of the spinal cord and femur contours. In all cases, editing contours was faster than manual contouring with an average time saving of 43.4% or 11.8 minutes per patient. The physician scored 240 structures with > 95% of structures receiving a score of 3 or 4. Of the structures reviewed, only 11 structures needed major revision or to be redone entirely. Our results indicate the evaluated auto-contouring solution has the potential to reduce clinical contouring time. The algorithm's performance is promising, but human review and some editing is required prior to clinical use. [ABSTRACT FROM AUTHOR]

Corey A Kemper,1 Casper Mihl,2,3 Bibi Martens,2,3 Michael C McDermott,2,4 Babs MF Hendriks2,3 1Bayer U.S. LLC, Bayer Pharmaceuticals, Radiology R&D, Indianola, PA, USA; 2Department of Radiology & Nuclear Medicine, Maastricht University Medical Center, Maastricht, the Netherlands; 3Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands; 4Bayer AG, Radiology R&D, Berlin, GermanyCorrespondence: Corey A Kemper, Bayer U.S. LLC, Bayer Pharmaceuticals, Radiology R&D, 1 Bayer Dr, Indianola, PA, USA, Tel +1 412 225 3907, Email corey.kemper@bayer.comPurpose: To compare an investigational device (MEDRAD® Centargo CT Injection System, “Centargo”) to the currently available MEDRAD® Stellant CT Injection System (“Stellant”), in terms of efficiency, injector performance, and user satisfaction.Patients and Methods: A total of 425 patients at two sites were enrolled; 198 patients in phase one, a randomized study (98 Stellant and 100 Centargo). The second observational phase included 227 patients who were injected with Centargo. Phase one recorded times for setup, disassembly, and patient changeovers. Demographic data, subjective image quality, and injection parameters were collected. Phase two assessed usability via a questionnaire provided to all end-users of both systems (radiographers).Results: Patient changeover times were statistically significantly faster with Centargo (15.4s ± 8.7s vs 53.7s ± 19.6s, p < 0.001). Centargo day-setup times were similar to Stellant (138.1s ± 92s vs 151.8s ± 30.6s, p = 0.33) and end-of-day-disassembly times were significantly slower (60.6s ± 27s vs 17.1s ± 12.9s, p < 0.001). Based on four different scenarios modelling patient throughput, the projected time savings with Centargo over Stellant was 40– 63%, with the highest efficiency improvements for higher throughputs and the use of larger contrast medium bottles. Both Centargo and Stellant usability averaged between “Very Easy” and “Easy” in all responses to the questionnaire. There were no instances of interrupted injections due to communication loss or detected air and no insufficient images due to injector performance. No safety issues were identified.Conclusion: Centargo was able to demonstrate improved efficiency as compared to Stellant while maintaining injector performance and high usability scores.Keywords: power injection, efficiency, time savings, usability, Centargo

The purpose of this study is to identify the impact of digitalization on reducing costs and time savings. The methodology used for this study is regression model and Pearson correlation analysis. Primary data were used to conduct the research with total 313 observations using Likert-scale method. Digitalization is used as independent variable while reducing costs and time savings are used as dependent variables. Based on the results at significance level at 0.000 the digitalization has significant impact on reducing costs and time savings. Public administration management, researchers and other related parties can use the results to determine the effect of digitalization on reducing costs and time savings.

Critical Chain Project Management (CCPM) has emerged as a notable approach in recent years for improving time management in construction projects. This methodology focuses on optimizing project schedules, and its impact on construction projects has been explored through a review of literature from the past five years. However, a theoretical understanding alone may not be sufficient for promoting the adoption of CCPM in the sector. Therefore, an experimental study was conducted to assess the practical impact of CCPM on shortening the timeline of a construction project. The study involved the use of CPM for the planning phase and CCPM for the execution phase of finishing works (drywalls, carpentry, painting) in three identical blocks of flats. At the completion of the project, an important economy of 36 days (around 20%) was achieved, and the project was completed in 151 days using CCPM compared to the planned 187 days using CPM. The research was limited to finishing works, and further studies are planned to explore the applicability of CCPM to other construction works. It is imperative to establish a continuous collaboration between researchers and practitioners in the construction industry, as research findings should be effectively applied in real-world scenarios.

Purpose: This retrospective work aims to evaluate the possible impact on intra‐ and inter‐observer variability, contouring time, and contour accuracy of introducing a pelvis computed tomography (CT) auto‐segmentation tool in radiotherapy planning workflow. Methods: Tests were carried out on five structures (bladder, rectum, pelvic lymph‐nodes, and femoral heads) of six previously treated subjects, enrolling five radiation oncologists (ROs) to manually re‐contour and edit auto‐contours generated with a male pelvis CT atlas created with the commercial software MIM MAESTRO. The ROs first delineated manual contours (M). Then they modified the auto‐contours, producing automatic‐modified (AM) contours. The procedure was repeated to evaluate intra‐observer variability, producing M1, M2, AM1, and AM2 contour sets (each comprising 5 structures × 6 test patients × 5 ROs = 150 contours), for a total of 600 contours. Potential time savings was evaluated by comparing contouring and editing times. Structure contours were compared to a reference standard by means of Dice similarity coefficient (DSC) and mean distance to agreement (MDA), to assess intra‐ and inter‐observer variability. To exclude any automation bias, ROs evaluated both M and AM sets as "clinically acceptable" or "to be corrected" in a blind test. Results: Comparing AM to M sets, a significant reduction of both inter‐observer variability (p < 0.001) and contouring time (‐45% whole pelvis, p < 0.001) was obtained. Intra‐observer variability reduction was significant only for bladder and femoral heads (p < 0.001). The statistical test showed no significant bias. Conclusion: Our atlas‐based workflow proved to be effective for clinical practice as it can improve contour reproducibility and generate time savings. Based on these findings, institutions are encouraged to implement their auto‐segmentation method. [ABSTRACT FROM AUTHOR]

Introduction: Estimating treatment effects as time savings in disease progression may be more easily interpretable than assessing the absolute difference or a percentage reduction. In this study, we investigate the statistical considerations of the existing method for estimating time savings and propose alternative complementary methods., Methods: We propose five alternative methods to estimate the time savings from different perspectives. These methods are applied to simulated clinical trial data that mimic or modify the Clinical Dementia Rating Sum of Boxes progression trajectories observed in the Clarity AD lecanemab trial., Results: Our study demonstrates that the proposed methods can generate more precise estimates by considering two crucial factors: (1) the absolute difference between treatment arms, and (2) the observed progression rate in the treatment arm., Discussion: Quantifying treatment effects as time savings in disease progression offers distinct advantages. To provide comprehensive estimations, it is important to use various methods., Highlights: We explore the statistical considerations of the current method for estimating time savings. We proposed alternative methods that provide time savings estimations based on the observed absolute differences. By using various methods, a more comprehensive estimation of time savings can be achieved., (© 2024 The Author(s). Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.)

The purpose of this study is to analyze the influence of several antecedents of customer satisfaction in the online shopping industry, namely site design, time savings, product variation, and shipping performance, and its consequence on customer satisfaction and word of mouth. This study uses purposive sampling with repeat buyer criteria. 100 samples qualify and deserve to be tested after testing their validity and reliability. The results showed that site design, time savings, and delivery performance significantly affected customer satisfaction. Meanwhile, site design, time savings, and product variations affect word of mouth. In addition, the results also confirm the hidden role of customer satisfaction as a partial mediating variable. Thus, the market must increase the availability of products and services to increase customer satisfaction in order to increase word of mouth activities.

The purpose of this study is to identify the impact of digitalization on reducing costs and time savings. The methodology used for this study is regression model and Pearson correlation analysis. Primary data were used to conduct the research with total 313 observations using Likert-scale method. Digitalization is used as independent variable while reducing costs and time savings are used as dependent variables. Based on the results at significance level at 0.000 the digitalization has significant impact on reducing costs and time savings. Public administration management, researchers and other related parties can use the results to determine the effect of digitalization on reducing costs and time savings. [ABSTRACT FROM AUTHOR]

Considerable observational evidence indicates that travel time, averaged across a population, is stable at about an hour a day. This implies both an upper and a lower bound to time that can be expended on travel. The upper bound explains the self-limiting nature of road traffic congestion, as well as the difficulty experienced in attempting mitigation: the prospect of delays deters some road users, who are attracted back following interventions aimed at relieving congestion. The lower bound implies that time savings cannot be the main economic benefit of transport investment, which means that conventional transport economic appraisal is misleading. In reality, the main benefit for users is increased access to desired destinations, made possible by faster travel, which is the origin of induced traffic. Access is subject to saturation, consistent with the evidence of travel demand saturation. However, access is difficult to monetise for inclusion in cost–benefit analysis. Consequential uplift in real estate values may be a more practical way of estimating access benefits, which is relevant to the possibility of capturing part of such uplift to help fund transport investment that enhances such access. [ABSTRACT FROM AUTHOR]

Background: Efforts to promote clean cooking through adoption of clean-burning fuels such as liquefied petroleum gas (LPG) are often based on the idea that near-exclusive use of LPG could lead to health improvements. However, benefits beyond health, such as time savings, could be more tangible and meaningful to LPG users. Objectives: This study investigated the effect of an LPG intervention on time spent cooking and collecting fuel, using objective measures of stove temperatures combined with self-reports under conditions of near-exclusive LPG use. We also investigated the perceived value of any time savings and potential economic and quality of life implications. Methods: We analyzed data from the Cardiopulmonary outcomes and Household Air Pollution trial in Puno, Peru, a randomized controlled trial with 180 participants assessing exposure and health impacts of an LPG stove, fuel, and behavioral intervention. Surveys conducted with 90 intervention women receiving free LPG and 90 control women cooking primarily with biomass assessed time spent cooking and collecting biomass fuel and use of time savings. Cooking time was objectively measured with temperature sensors on all stoves. Qualitative interviews explored perceptions and use of time savings in more depth. Results: Intervention women spent 3.2 fewer hours cooking and 1.9 fewer hours collecting fuel per week compared to control women, but cooked on average 1.0 more meals per day. Participants perceived time saved from LPG positively, reporting more time for household chores, leisure activities, and activities with income-generating potential such as caring for animals and working in fields. Discussion: This paper suggests that the benefits of LPG extend beyond health and the environment. LPG use could also lead to economic and quality of life gains, through increased time for work, rest, and consumption of hot meals, and reduced arduous biomass fuel collection.

The paper deals with the issue of delays of public transport vehicles at the signal controlled junctions. Based on the road traffic survey results, the average values of vehicle delays were determined. By using those values, it is possible to define time savings for the vehicles and mainly for passengers that are transported. The time savings were determined based on the relationships and coefficients defined in this paper.

The overview of some theoretical approaches to the mechanism of economic valuation of travel time variability and the value of travel time savings of urban passenger transport is provided. Each estimate depends on the demographic characteristics of the population, the type of transport, time, location and purpose of the trip, as well as the available choice of alternatives. The decisions of experts in a context of consumption choice based on utility maximization, subject to constraints on income and the minimum amount of time required by each activity are described. There in sum, there is a broad consensus on the approach adopted and the relevant variables and categories, as well as a degree of similarity in the specific values recommended.

Virtual care holds promise for offering services to Veterans Affairs (VA) patients who have barriers to accessing care. In 2016, the VA began issuing video-enabled tablets to Veterans with geographic, clinical, and/or social barriers to in-person care. To complement a national evaluation of system-level implementation and effectiveness of these tablets, we sought to understand whether the VA-issued tablets generated money and/or time savings for patients. We distributed a survey to 2,120 Veterans who received tablets and administered a follow-up survey 3–6 months later. The final analysis included 594 and 399 patients who responded to questions about money and time savings, respectively. We used poststratification survey weighting methods to address potential selection and nonresponse bias. In multinomial logistic regressions and logistic regressions, we examined patient characteristics associated with reported money and time savings. A majority of survey respondents reported that the tablets saved them money (89%) and time (71%). Respondents were more likely to report monetary savings if they lived at a greater distance from the VA, if they experienced travel barriers, and if they did not have a mental health condition. Respondents were more likely to report time savings if they were <45 or ≥65 years of age, employed, and reported more overall technology experience. Findings may inform policy decisions regarding patient targeting and training as VA aims to expand its use of video telehealth technology. [ABSTRACT FROM AUTHOR]

he manufacturing process cycle is a critical sub-stage in integrated Supply Chain Management. The savings from manufacturing supply chain of Supply Chain Management will improve the revenue and returns. BHPV in Visakhapatnam, a public sector engineering unit is made a subsidiary in 2008 and merged into BHEL in 2010. The study is formulated to examine the savings in manufacturing hours and cost in four manufacturing cycle changes in the Supply Chain Management process in each year from 2008-09 to 2012-13. Therefore, a total of 20 manufacturing cycles in the supply chain management are collected at two intervals, one before and another after the change is implemented. The evaluation is done in terms of manufacturing cost and hours saved and its impact on financial performance parameters Return on Investment, Return on Assets, return on sales and Value Added. The analysis shows hypothesis H1 and H2 are true as significant relationship exists for the years under consideration with savings in cost and hours. The Impact of manufacturing process cycle changes on the financial performance in each year is positive except for the year 2009-10. However, the value added is positive and increasing for all the years under consideration. The changes in the manufacutring cycles of supply chain management have contributed to the revenue and time improvement in BHEL-HPV Plant at Visakhapatnam. [ABSTRACT FROM AUTHOR]

Background: Over the past few years, major inspection findings have been identified in the "management of adverse reactions" that may be due to increasing workload in pharmaceutical organizations impacting the correctness of information in individual case safety reports (ICSRs). Although retrospective quality check (Retro-QC) and late submission analyses are important steps in ensuring ICSR quality, their manual application poses several challenges that can be overcome through automation., Objectives: To improve the efficiency of the Retro-QC analysis and late submission analysis using a computer-operated tool called Compliance and Metrics Management (CMM) tool, and to measure the tool's effectiveness in terms of productivity, time, and cost savings by comparing against the manual process., Methods: Time savings were calculated by measuring the difference in time taken during the manual process versus the automated process. Cost savings were measured in terms of hourly remuneration for the time saved. Productivity was calculated as the difference between the number of cases handled in the manual versus automated process. Thus, the overall efficiency was measured in terms of time and cost savings along with increased productivity., Results: Automation resulted in time savings of 49% and cost savings of 43% for Retro-QC analysis, and the productivity level increased by 67%. For late submission analysis, the CMM tool resulted in time savings of 88% and cost savings of 87%., Conclusion: CMM tool enhanced the efficiency of both Retro-QC and late submission analyses by increasing productivity along with time and cost savings. It also reduced the number of errors, thereby enhancing the accuracy of the process and overall compliance., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)

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Background: The benefits of digital pathology for workflow improvement and thereby cost savings in pathology, at least partly outweighing investment costs, are being increasingly recognised. Successful implementations in a variety of scenarios have started to demonstrate the cost benefits of digital pathology for both research and routine diagnosis, contributing to a sound business case encouraging further adoption. To further support new adopters, there is still a need for detailed assessment of the impact that this technology has on the relevant pathology workflows, with an emphasis on time‐saving. Aims: To assess the impact of digital pathology adoption on logistic laboratory tasks (i.e. not including pathologists' time for diagnosis‐making) in the Laboratorium Pathologie Oost Nederland, a large regional pathology laboratory in The Netherlands. Methods and results: To quantify the benefits of digitisation, we analysed the differences between the traditional analogue and new digital workflows, carried out detailed measurements of all relevant steps in key analogue and digital processes, and compared the time spent. We modelled and assessed the logistic savings in five workflows: (i) routine diagnosis; (ii) multidisciplinary meeting; (iii) external revision requests; (iv) extra stainings; and (v) external consultation. On average, >19 working hours were saved on a typical day by working digitally, with the highest savings in routine diagnosis and multidisciplinary meeting workflows. Conclusions: By working digitally, a significant amount of time could be saved in a large regional pathology laboratory with a typical case mix. We also present the data in each workflow per task and concrete logistic steps to allow extrapolation to the context and case mix of other laboratories. [ABSTRACT FROM AUTHOR]

The paper deals with the issue of delays of public transport vehicles at the signal controlled junctions. Based on the road traffic survey results, the average values of vehicle delays were determined. By using those values, it is possible to define time savings for the vehicles and mainly for passengers that are transported. The time savings were determined based on the relationships and coefficients defined in this paper. [ABSTRACT FROM AUTHOR]

Social network research has shown that knowledge sharing connections facilitate access to valuable resources. However, little is known about which knowledge sharing connections save knowledge seekers the most time on their daily tasks. To address this gap, this research analyses knowledge sharing connections that provide time savings, measured as the time individuals saved on daily tasks as a result of receiving knowledge from other employees. The research evaluates time savings based on the strength of connection, the network distance between the seeker and provider and the provider’s centrality in the network. To conduct this study, the research team analysed a data-set of 10,849 knowledge sharing dyads reported through a survey administered in one department in a large construction and engineering organization. Data were analysed using social network analysis and multiple regression quadratic assignment procedure. Results showed that stronger connections were assessed as more beneficial for time savings, especially when the connections were with central actors who had higher closeness centrality scores. Knowledge seekers also had a higher assessment of time savings when they were closer (in terms of network distance) to the knowledge provider. These results show that knowledge network reach and strong knowledge connections are essential for achieving everyday work efficiency. Furthermore, the results add to theories of strong and weak connections by showing that strong ties are favourable for achieving time savings in the context of construction and engineering organizations. [ABSTRACT FROM PUBLISHER]

Pneumonia is the leading cause of mortality for children under five years in sub-Saharan Africa. Household air pollution has been found to increase risk of pneumonia, especially due to exposure from dirty burning biomass fuels. It has been suggested that advanced stoves, which burn fuel more efficiently and reduce smoke emissions, may help to reduce household air pollution in poor, rural settings. This qualitative study aims to provide an insight into the household costs and perceived benefits from use of the stove in Malawi. It was conducted alongside The Cooking and Pneumonia Study (CAPS), the largest village cluster-level randomised controlled trial of an advanced combustion cookstove intervention to prevent pneumonia in children under five to date. In 2015, using 100 semi-structured interviews this study assessed household time use and perceptions of the stove from both control and intervention participants taking part in the CAPS trial in Chilumba. Household direct and indirect costs associated with the intervention were calculated. Users overwhelming liked using the stove. The main reported benefits were reduced cooking times and reduced fuel consumption. In most interviews, the health benefits were not initially identified as advantages of the stove, although when prompted, respondents stated that reduced smoke emissions contributed to a reduction in respiratory symptoms. The cost of the stove was much higher than most respondents said they would be willing to pay. The stoves were not primarily seen as health products. Perceptions of limited impact on health was subsequently supported by the CAPS trial data which showed no significant effect on pneumonia. While the findings are encouraging from the perspective of acceptability, without innovative financing mechanisms, general uptake and sustained use of the stove may not be possible in this setting. The findings also raise the question of whether the stoves should be marketed and championed as ‘health interventions’. [ABSTRACT FROM AUTHOR]

Alternative cook stoves that replace solid fuels with cleaner energy sources, such as biogas, are gaining popularity in low-income settings across Asia, Africa and South America. Published research on these technologies focuses on their potential to reduce indoor air pollution and improve respiratory health. Effects on other cooking related aspects, such as diets and women’s time management, are less understood. In this study in southern India, we investigate if using biogas cook stoves alters household diets and women’s time management. We compare treatment households who are supplied with a biogas cook stove with comparison households who do not have access to these stoves, while controlling for several socio-economic factors. We find that diets of treatment households are more diverse than diets of comparison households. In addition, women from treatment households spend on average 40 minutes less cooking and 70 minutes less collecting firewood per day than women in comparison households. This study illustrates that alongside known benefits for respiratory health, using alternative cook stoves may benefit household diets and free up women’s time. To inform development investments and ensure these co-benefits, we argue that multiple dimensions of sustainability should be considered in evaluating the impact of alternative cook stoves.

Data visualization is a key tool to drive both end user adoption and change management activities within data initiatives and especially so in sales environments. Data is as much a part of the problem as the solution itself. There’s too much of it, it’s difficult to interpret and sellers hold on to tactical workload out of distrust in the data systems they are provided with. A data-driven approach to the sales engagement cycle can fundamentally improve performance. Using an analytical approach to determine client needs and sales ‘signals’, sales engagement can be tuned to be in sync with market needs. However, a range of technical, organisational and cultural issues need to be addressed before such a solution can truly start to deliver results. A prototype has been developed and implemented within IBM Digital Sales Europe to test the effectiveness of a data-driven approach to territory management. This practitioner focussed paper looks at the impact on business results that the programme used to introduce such new territory management methods had.It uses the 6 wise men approach to consider the nature of the problem and where the initiative directly impacted outcomes. Its answers questions on (1) what was the data driven initiative being implemented, (2) why it was important, (3) how it was implemented, (4) when it took place, (5) who has benefited and (6) where business value was created. This paper concludes that data initiatives require considerable transformation effort to be successful. Moreover, it identifies that there is a broad range of benefits available beyond the immediate territory management effectiveness of a data-driven client selection methodology. [ABSTRACT FROM PUBLISHER]

Objective: Previous research suggests that erythropoiesis stimulating agent (ESA) administration in dialysis is a time-consuming task and switching to less frequently dosed ESAs may offer operational efficiencies. Our objective was to describe and measure the time spent on tasks in the ESA administration process in US dialysis centers, and to estimate potential efficiency gains of using weekly (QW) administration vs three-times-per-week (TIW) administration.Methods: We conducted a time and motion study of staff time required to prepare, administer and document ESA doses. Dialysis centers using intravenous administration of TIW epoetin alfa (EPO) or QW darbepoetin alfa (DPO) were selected in pairs (one EPO, one DPO) from the same organization to help control for differences in ESA protocols and staffing patterns across organizations. ESA-related tasks were timed by trained observers. Time savings of TIW vs QW administration were estimated. Staff were interviewed about alternate activities that could be accomplished if time were saved in the ESA process.Results: A total of 200 administrations were observed (81 DPO, 119 EPO). A mean of 2.26 (95% CI: 2.1-2.5) minutes per dose were required for ESA administration. ESA process time per administration did not vary significantly between EPO and DPO (p = 0.83). Estimated potential monthly staff time savings for an average facility of 70 patients totaled 23 hours, due to fewer ESA administrations using QW DPO. Patient education and fulfillment of care plans were identified as opportunities for improved care processes that could be implemented if staff time was freed up from the ESA process.Limitations: Results should not be generalized to other countries, ESAs and/or dosing frequencies.Conclusions: Switching from TIW EPO to QW DPO can result in time savings due to fewer administrations and provide opportunities to redirect nurse time towards activities aimed at improving patient care. [ABSTRACT FROM AUTHOR]

Perceived time savings by travelling faster is often cited as a motivation for drivers’ speeding behaviour. These time savings, however, come at a cost of significant road injuries and fatalities. While it is known that drivers tend to overestimate the time savings attributable to speeding there is little empirical evidence on how much time drivers genuinely save during day-to-day urban driving and how this relates to speeding-related crashes. The current paper reports on a study to address the lack of empirical evidence on this issue using naturalistic driving data collected from 106 drivers over a period of five weeks. The results show that the average driver saves 26 s/day or 2 min/week by speeding. More importantly, the cost of these time savings is one fatality for every 24,450 h saved by the population on 100 km/h roads in dry conditions and one injury for every 2458 h saved on the same roads. Full speed compliance – and consequently a dramatic reduction in the road toll – could be achieved through almost imperceptible increases in travel time by each driver. [ABSTRACT FROM AUTHOR]

Thessaloniki undergoes radical changes; the city, although negatively affected by the recurrent effects of the economic crisis, is tentatively moving along the path to recovery. Taking advantage of lower rates in car use due to economic reasons, a Public Transport (PT) system reform, where the impact of adding value can thus be bigger, should be posed at the crux of the city's agenda. This reform refers to a provision of services contributing to the development of “accessible – affordable – high-quality” PT, which should, however, be based on “smart-and-soft” interventions that respect the limited budget while upgrading the perceived PT quality. Based on a dedicated examination of Thessaloniki, this paper seeks to determine users' needs and the impact on perceived time savings (and on modal shift) of key investments based on the exploitation of Information and Communications Technology (ICT) for PT. The paper examines the soft interventions because the current economic system cannot afford extra pressure from the adoption of costly measures. The paper concludes by verifying that ICT can play a catalytic role in changing passengers' perception concerning time savings and can encourage passengers to use PT more often. [ABSTRACT FROM AUTHOR]

Highlights: [•] The value of improved labour market accessibility is estimated. [•] We use two different methods: commuting and hedonic house price models. [•] We find that both models can give similar results. [Copyright &y& Elsevier]