1. The clinical relevance of oliguria in the critically ill patient: Analysis of a large observational database
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Vincent, J, Ferguson, A, Pickkers, P, Jakob, S, Jaschinski, U, Almekhlafi, G, Leone, M, Mokhtari, M, Fontes, L, Bauer, P, Sakr, Y, Tomas, E, Bibonge, E, Charra, B, Faroudy, M, Doedens, L, Farina, Z, Adler, D, Balkema, C, Kok, A, Alaya, S, Gharsallah, H, Muzha, D, Temelkov, A, Georgiev, G, Simeonov, G, Tsaryanski, G, Georgiev, S, Seliman, A, Vrankovic, S, Vucicevic, Z, Gornik, I, Barsic, B, Husedzinovic, I, Pavlik, P, Manak, J, Kieslichova, E, Turek, R, Fischer, M, Valkova, R, Dadak, L, Dostal, P, Malaska, J, Hajek, R, Zidkova, A, Lavicka, P, Starkopf, J, Kheladze, Z, Chkhaidze, M, Kaloiani, V, Medve, L, Sarkany, A, Kremer, I, Marjanek, Z, Tamasi, P, Krupnova, I, Vanags, I, Liguts, V, Pilvinis, V, Vosylius, S, Kekstas, G, Balciunas, M, Kolbusz, J, Kubler, A, Mielczarek, B, Mikaszewska-Sokolewicz, M, Kotfis, K, Tamowicz, B, Sulkowski, W, Smuszkiewicz, P, Pihowicz, A, Trejnowska, E, Hagau, N, Filipescu, D, Droc, G, Lupu, M, Nica, A, Stoica, R, Tomescu, D, Constantinescu, D, Valcoreanu 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M., Jaschinski U., Almekhlafi G. A., Leone M., Mokhtari M., Fontes L. E., Bauer P. R., Sakr Y., Tomas E., Bibonge E. A., Charra B., Faroudy M., Doedens L., Farina Z., Adler D., Balkema C., Kok A., Alaya S., Gharsallah H., Muzha D., Temelkov A., Georgiev G., Simeonov G., Tsaryanski G., Georgiev S., Seliman A., Vrankovic S., Vucicevic Z., Gornik I., Barsic B., Husedzinovic I., Pavlik P., Manak J., Kieslichova E., Turek R., Fischer M., Valkova R., Dadak L., Dostal P., Malaska J., Hajek R., Zidkova A., Lavicka P., Starkopf J., Kheladze Z., Chkhaidze M., Kaloiani V., Medve L., Sarkany A., Kremer I., Marjanek Z., Tamasi P., Krupnova I., Vanags I., Liguts V., Pilvinis V., Vosylius S., Kekstas G., Balciunas M., Kolbusz J., Kubler A., Mielczarek B., Mikaszewska-Sokolewicz M., Kotfis K., Tamowicz B., Sulkowski W., Smuszkiewicz P., Pihowicz A., Trejnowska E., Hagau N., Filipescu D., Droc G., Lupu M. N., Nica A., Stoica R., Tomescu D. R., Constantinescu D. L., Valcoreanu Zbaganu G. M., Slavcovici A., Bagin V., Belsky D., Palyutin S., Shlyapnikov S., Bikkulova D., Gritsan A., Natalia G., Makarenko E., Kokhno V., Tolkach A., Kokarev E., Belotserkovskiy B., Zolotukhin K., Kulabukhov V., Soskic L., Palibrk I., Jankovic R., Jovanovic B., Pandurovic M., Bumbasirevic V., Uljarevic B., Surbatovic M., Ladjevic N., Slobodianiuk G., Sobona V., Cikova A., Gebhardtova A., Jun C., Yunbo S., Dong J., Feng S., Duan M., Xu Y., Xue X., Gao T., Xing X. Z., Zhao X., Li C. H., Gengxihua G., Tan H., Xu J., Jiang L., Tiehe Q., Bingyu Q., Shi Q., Lv Z., Zhang L., Jingtao L., Zhen Z., Wang Z., Wang T. H., Yuhong L., Zhai Q., Chen Y., Wang C., Jiang W., Ruilan W., Xiaobo H., Ge H., Yan T., Yuhui C., Zhang J., Jian-Hong F., Zhu H., Huo F., Wang Y., Li C., Zhuang M., Ma Z., Sun J., Liuqingyue L., Yang M., Meng J., Ma S., Kang Y., Yu L., Peng Q., Wei Y., Zhang W., Sun R., Yeung A., Wan W. L., Sin K. K. C., Lee K. L., Wijanti M., Widodo U., Samsirun H., Sugiman T., Wisudarti C., Maskoen T. T., Hata N., Kobe Y., Nishida O., Miyazaki D., Nunomiya S., Uchino S., Kitamura N., Yamashita K., Hashimoto S., Fukushima H., Adib N. A. N., Tai L. L., Tony B., Bigornia R. R., Palo J. E., Chatterjee S., Tan B. H., Kong A., Goh S., Lee C. -C., Pothirat C., Khwannimit B., Theerawit P., Pornsuriyasak P., Piriyapatsom A., Mukhtar A., Hamdy A. N., Hosny H., Ashraf A., Nowruzinia S., Lotfi A. H., Zand F., Nikandish R., Moghaddam O. M., Cohen J., Sold O., Sfeir T., Hasan A. Y., Abugaber D., Ahmad H., Tantawy T., Baharoom S., Algethamy H., Amr A., Almekhlafi G., Coskun R., Sungur M., Cosar A., Gucyetmez B., Demirkiran O., Senturk E., Ulusoy H., Atalan H. K., Serin S., Kati I., Alnassrawi Z., Almemari A., Krishnareddy K., Kashef S., Alsabbah A., Poirier G., Marshall J. C., Herridge M., Fernandez-Medero R., Fulda G., Banschbach S., Quintero J., Schroeder E., Sicoutris C., Gueret R., Kashyap R., Bauer P., Nanchal R., Wunderink R. G., Jimenez E., Ryan A., Prince D., Edington J., Van Haren F., Bersten A., Hawkins D. J., Kilminster M., Sturgess D., Ziegenfuss M., O' Connor S., Lipman J., Campbell L., McAllister R., Roberts B., Williams P., Parke R., Seigne P., Freebairn R., Nistor D., Oxley C., Young P., Valentini R., Wainsztein N., Comignani P., Casaretto M., Sutton G., Villegas P., Galletti C., Neira J., Rovira D., Hidalgo J., Sandi F., Caser E., Thompson M. M., D'Agostino Dias M., Lunardi M. C., Youssef N. C., Lobo S., Silva R., Sales J. A., Melo L. M. C., Oliveira M., Fonte M., Grion C., Feijo C., Rezende V., Assuncao M., Neves A. P., Gusman P., Dalcomune D., Teixeira C., Kaefer K., Maia I., Dantas V. S., Filho R. C., Amorim F., Assef M., Schiavetto P., Houly J., Bianchi F., Dias F., Avila C., Rego L., Castro P., Passos J., Mendes C., Mecatti G. C., Ferrreira M., Irineu V., Guerreiro M., Ugarte S., Tomicic V., Godoy C., Samaniego W., Escamilla I., Castro Castro L. F., Duque G. L., Diaz-Guio D., Benitez F., Urrego A. G., Buitrago R., Ortiz G., Villalba Gaviria M. C., Salas D., Ramirez-Arce J., Salgado E., Morocho D., Vergara J., Sang M. C., Orellana-Jimenez C., Garrido L., Diaz O., Resiere D., Osorio C., De La Vega A., Carrillo R., Sanchez V., Villagomez A., Zubieta R. M., Sandia M., Zalatiel M., Poblano M., Gonzalez D. R., Arrazola F., Juan Francisco L. L., Namendys-Silva S. A., Moya R. G., Hernandez M., Rodriguez Cadena D. M., Islas I. L., Ballesteros Zarzavilla C. M., Matos A., Oyanguren I., Cerna J., Sierra R. Q., Jimenez R., Castillo L., Ocal R., Sencan A., Mareque Gianoni S. M., Deicas A., Hurtado J., Burghi G., Martinelli A., Von Der Osten I., Du Maine C., Bhattacharyya M., Bandyopadhyay S., Yanamala S., Gopal P., Sahu S., Ibrahim M., Rathod D., Mukundan N., Dewan A., Amin P., Samavedam S., Shah B., Gurupal G., Lahkar B., Mandal A. K., Sircar M., Ghosh S., Balasubramani V., Kapadia F., Vadi S., Nair K., Tripathy S., Nandakumar S., Sharma J., Kar A., Jha S., Zirpe K., Patel M., Bhavsar A., Samaddar D. P., Kulkarni A., Hashmi M., Ali W., Nadeem S., Indraratna K., Margarit A., Urbanek P., Schlieber J., Reisinger J., Auer J., Hartjes A., Lerche A., Janous T., Kink E., Krahulec W., Smolle K. -H., Van Der Schueren M., Thibo P., Vanhoof M., Ahmet I., Gadisseux P., Dufaye P., Jacobs O., Fraipont V., Biston P., Dive A., Bouckaert Y., Gilbert E., Gressens B., Pinck E., Collin V., De Waele J. J., Rimachi R., Gusu D., De Decker K., Mandianga K., Heytens L., Wittebole X., Spapen H., Van Collie O., Vandenheede W., Rogiers P., Kolodzeike P., Kruse M., Andersen T., Harjola V. -P., Saarinen K., Durocher A., Moulront S., Lepape A., Losser M. -R., Cabaret P., Kalaitzis E., Zogheib E., Charve P., Francois B., Lefrant J. -Y., Beilouny B., Forceville X., Misset B., Jacobs F., Floccard B., Payen D., Wynckel A., Castelain V., Faure A., Lavagne P., Lepoivre T., Moussa M. D., Vieillard-Baron A., Durand M., Gainnier M., Ichai C., Arens S., Hoffmann C., Kaffarnik M., Scharnofske C. -J., Voigt I., Peckelsen C., Weber M., Gille J., Lange A., Schoser G., Sablotzki A., Bluethgen A., Vogel F., Tscheu A., Fuchs T., Wattenberg M., Helmes T., Scieszka S., Heintz M., Sakka S., Kohler J., Fiedler F., Danz M., Riessen R., Kerz T., Kersten A., Tacke F., Marx G., Volkert T., Schmutz A., Nierhaus A., Kluge S., Abel P., Janosi R. A., Utzolino S., Bracht H., Toussaint S., Peftoulidou M. G., Myrianthefs P., Armaganidis A., Routsi C., Xini A., Mouloudi E., Kokoris I., Kyriazopoulos G., Vlachos S., Lavrentieva A., Partala P., Nakos G., Moller A., Stefansson S. O., Barry J., O'Leary R. A., Motherway C., Faheem M., Dunne E., Donnelly M., Konrad T., Bonora E., Achilli C., Rossi S., Castiglione G., Peris A., Albanese D., Stocchetti N., Citerio G., Mozzoni L., Sisillo E., De Negri P., Savioli M., Vecchiarelli P., Puflea F., Stankovic V., Minoja G., Montibeller S., Calligaro P., Sorrentino R., Feri M., Zambon M., Colombaroli E., Giarratano A., Pellis T., Capra C., Antonelli M., Gullo A., Chelazzi C., De Capraris A., Patroniti N., Girardis M., Franchi F., Berlot G., Buttigieg M., Ponssen H., Ten Cate J., Bormans L., Husada S., Buise M., Van Der Hoven B., Reidinga A., Kuiper M., Kluge G., Den Boer S., Kesecioglu J., Van Leeuwen H., Flaatten H., Mo S., Branco V., Rua F., Lafuente E., Sousa M., Catorze N., Barros M., Pereira L., De Oliveira A. V., Gomes J., Gaspar I., Pereira M. F., Cymbron M., Dias A., Almeida E., Beirao S., Serra I., Ribeiro R., Povoa P., Faria F., Costa-E-Silva Z., Nobrega J. J., Fernandes F., Gabriel J., Voga G., Rupnik E., Kosec L., Povsic M. K., Osojnik I., Tomic V., Sinkovic A., Gonzalez J., Zavala E., Valenzuela J. P., Marina L., Vidal-Cortes P., Posada P., Martin-Loeches I., Guillen N. M., Palomar M., Sole-Violan J., Torres A., Gonzalez Gallego M. A., Aguilar G., Allue R. M., Argueso M., Parejo M., Navarro M. P., Jose A., Nin N., Lerma F. A., Martinez O., Lozano E. T., Lopez S. A., Perez Granda M. J., Moreno S., Llubia C., Martos C. D. L. F., Gonzalez-Arenas P., Fernandez N. L., Rueda B. G., Pons I. E., Cruza N., Maroto F., Estella A., Ferrer A., Fraile L. I., Quindos B., Quintano A., Tebar M. T., Cardinal P., Reyes A., Rodriguez A., Abella A., Del Valle S. G., Yus S., Maseda E., Berezo J. A., Pedregosa A. T., Laplaza C., Ferrer R., Rico-Feijoo J., Rodriguez M., Monedero P., Eriksson K., Lind D., Chabanel D., Zender H., Heer K., Frankenberger B., Jakob S., Haller A., Matthew S., Downes R., Groba C. B., Johnston A., Meacher R., Keays R., Haji-Michael P., Tyler C., Jones S., Tyl D., Ball A., Vogel J., Booth M., Downie P., Watters M., Brett S., Garfield M., Everett L., Heenen S., Dhir S., Beardow Z., Mostert M., Brosnan S., Pinto N., Harris S., Summors A., Norton A., Rose A., Appelboam R., Davies O., Vickers E., Agarwal B., Szakmany T., Wimbush S., Welters I., Pearse R., Hollands R., Kirk-Bayley J., Fletcher N., Bray B., Brealey D., Alexander P., Henderson S., Hargreaves C., Black H., Gowda K, Citerio G, Vincent, J, Ferguson, A, Pickkers, P, Jakob, S, Jaschinski, U, Almekhlafi, G, Leone, M, Mokhtari, M, Fontes, L, Bauer, P, Sakr, Y, Tomas, E, Bibonge, E, Charra, B, Faroudy, M, Doedens, L, Farina, Z, Adler, D, Balkema, C, Kok, A, Alaya, S, Gharsallah, H, Muzha, D, Temelkov, A, Georgiev, G, Simeonov, G, Tsaryanski, G, Georgiev, S, Seliman, A, Vrankovic, S, Vucicevic, Z, Gornik, I, Barsic, B, Husedzinovic, I, Pavlik, P, Manak, J, Kieslichova, E, Turek, R, Fischer, M, Valkova, R, Dadak, L, Dostal, P, Malaska, J, Hajek, R, Zidkova, A, Lavicka, P, Starkopf, J, Kheladze, Z, Chkhaidze, M, Kaloiani, V, Medve, L, Sarkany, A, Kremer, I, Marjanek, Z, Tamasi, P, Krupnova, I, Vanags, I, Liguts, V, Pilvinis, V, Vosylius, S, Kekstas, G, Balciunas, M, Kolbusz, J, Kubler, A, Mielczarek, B, Mikaszewska-Sokolewicz, M, Kotfis, K, Tamowicz, B, Sulkowski, W, Smuszkiewicz, P, Pihowicz, A, Trejnowska, E, Hagau, N, Filipescu, D, Droc, G, Lupu, M, Nica, A, Stoica, R, Tomescu, D, Constantinescu, D, Valcoreanu Zbaganu, G, Slavcovici, A, Bagin, V, Belsky, D, Palyutin, S, Shlyapnikov, S, Bikkulova, D, Gritsan, A, Natalia, G, Makarenko, E, Kokhno, V, Tolkach, A, Kokarev, E, Belotserkovskiy, B, Zolotukhin, K, Kulabukhov, V, Soskic, L, Palibrk, I, Jankovic, R, Jovanovic, B, Pandurovic, M, Bumbasirevic, V, Uljarevic, B, Surbatovic, M, Ladjevic, N, Slobodianiuk, G, Sobona, V, Cikova, A, Gebhardtova, A, Jun, C, Yunbo, S, Dong, J, Feng, S, Duan, M, Xu, Y, Xue, X, Gao, T, Xing, X, Zhao, X, Li, C, Gengxihua, G, Tan, H, Xu, J, Jiang, L, Tiehe, Q, Bingyu, Q, Shi, Q, Lv, Z, Zhang, L, Jingtao, L, Zhen, Z, Wang, Z, Wang, T, Yuhong, L, Zhai, Q, Chen, Y, Wang, C, Jiang, W, Ruilan, W, Xiaobo, H, Ge, H, Yan, T, Yuhui, C, Zhang, J, Jian-Hong, F, Zhu, H, Huo, F, Wang, Y, Zhuang, M, Ma, Z, Sun, J, Liuqingyue, L, Yang, M, Meng, J, Ma, S, Kang, Y, Yu, L, Peng, Q, Wei, Y, Zhang, W, Sun, R, Yeung, A, Wan, W, Sin, K, Lee, K, Wijanti, M, Widodo, U, Samsirun, H, Sugiman, T, Wisudarti, C, Maskoen, T, Hata, N, Kobe, Y, Nishida, O, Miyazaki, D, Nunomiya, S, Uchino, S, Kitamura, N, Yamashita, K, Hashimoto, S, Fukushima, H, Adib, N, Tai, L, Tony, B, Bigornia, R, Palo, J, Chatterjee, S, Tan, B, Kong, A, Goh, S, Lee, C, Pothirat, C, Khwannimit, B, Theerawit, P, Pornsuriyasak, P, Piriyapatsom, A, Mukhtar, A, Hamdy, A, Hosny, H, Ashraf, A, Nowruzinia, S, Lotfi, A, Zand, F, Nikandish, R, Moghaddam, O, Cohen, J, Sold, O, Sfeir, T, Hasan, A, Abugaber, D, Ahmad, H, Tantawy, T, Baharoom, S, Algethamy, H, Amr, A, Coskun, R, Sungur, M, Cosar, A, Gucyetmez, B, Demirkiran, O, Senturk, E, Ulusoy, H, Atalan, H, Serin, S, Kati, I, Alnassrawi, Z, Almemari, A, Krishnareddy, K, Kashef, S, Alsabbah, A, Poirier, G, Marshall, J, Herridge, M, Fernandez-Medero, R, Fulda, G, Banschbach, S, Quintero, J, Schroeder, E, Sicoutris, C, Gueret, R, Kashyap, R, Nanchal, R, Wunderink, R, Jimenez, E, Ryan, A, Prince, D, Edington, J, Van Haren, F, Bersten, A, Hawkins, D, Kilminster, M, Sturgess, D, Ziegenfuss, M, O' Connor, S, Lipman, J, Campbell, L, Mcallister, R, Roberts, B, Williams, P, Parke, R, Seigne, P, Freebairn, R, Nistor, D, Oxley, C, Young, P, Valentini, R, Wainsztein, N, Comignani, P, Casaretto, M, Sutton, G, Villegas, P, Galletti, C, Neira, J, Rovira, D, Hidalgo, J, Sandi, F, Caser, E, Thompson, M, D'Agostino Dias, M, Lunardi, M, Youssef, N, Lobo, S, Silva, R, Sales, J, Melo, L, Oliveira, M, Fonte, M, Grion, C, Feijo, C, Rezende, V, Assuncao, M, Neves, A, Gusman, P, Dalcomune, D, Teixeira, C, Kaefer, K, Maia, I, Dantas, V, Filho, R, Amorim, F, Assef, M, Schiavetto, P, Houly, J, Bianchi, F, Dias, F, Avila, C, Rego, L, Castro, P, Passos, J, Mendes, C, Mecatti, G, Ferrreira, M, Irineu, V, Guerreiro, M, Ugarte, S, Tomicic, V, Godoy, C, Samaniego, W, Escamilla, I, Castro Castro, L, Duque, G, Diaz-Guio, D, Benitez, F, Urrego, A, Buitrago, R, Ortiz, G, Villalba Gaviria, M, Salas, D, Ramirez-Arce, J, Salgado, E, Morocho, D, Vergara, J, Sang, M, Orellana-Jimenez, C, Garrido, L, Diaz, O, Resiere, D, Osorio, C, De La Vega, A, Carrillo, R, Sanchez, V, Villagomez, A, Zubieta, R, Sandia, M, Zalatiel, M, Poblano, M, Gonzalez, D, Arrazola, F, Juan Francisco, L, Namendys-Silva, S, Moya, R, Hernandez, M, Rodriguez Cadena, D, Islas, I, Ballesteros Zarzavilla, C, Matos, A, Oyanguren, I, Cerna, J, Sierra, R, Jimenez, R, Castillo, L, Ocal, R, Sencan, A, Mareque Gianoni, S, Deicas, A, Hurtado, J, Burghi, G, Martinelli, A, Von Der Osten, I, Du Maine, C, Bhattacharyya, M, Bandyopadhyay, S, Yanamala, S, Gopal, P, Sahu, S, Ibrahim, M, Rathod, D, Mukundan, N, Dewan, A, Amin, P, Samavedam, S, Shah, B, Gurupal, G, Lahkar, B, Mandal, A, Sircar, M, Ghosh, S, Balasubramani, V, Kapadia, F, Vadi, S, Nair, K, Tripathy, S, Nandakumar, S, Sharma, J, Kar, A, Jha, S, Zirpe, K, Patel, M, Bhavsar, A, Samaddar, D, Kulkarni, A, Hashmi, M, Ali, W, Nadeem, S, Indraratna, K, Margarit, A, Urbanek, P, Schlieber, J, Reisinger, J, Auer, J, Hartjes, A, Lerche, A, Janous, T, Kink, E, Krahulec, W, Smolle, K, Van Der Schueren, M, Thibo, P, Vanhoof, M, Ahmet, I, Gadisseux, P, Dufaye, P, Jacobs, O, Fraipont, V, Biston, P, Dive, A, Bouckaert, Y, Gilbert, E, Gressens, B, Pinck, E, Collin, V, De Waele, J, Rimachi, R, Gusu, D, De Decker, K, Mandianga, K, Heytens, L, Wittebole, X, Spapen, H, Van Collie, O, Vandenheede, W, Rogiers, P, Kolodzeike, P, Kruse, M, Andersen, T, Harjola, V, Saarinen, K, Durocher, A, Moulront, S, Lepape, A, Losser, M, Cabaret, P, Kalaitzis, E, Zogheib, E, Charve, P, Francois, B, Lefrant, J, Beilouny, B, Forceville, X, Misset, B, Jacobs, F, Floccard, B, Payen, D, Wynckel, A, Castelain, V, Faure, A, Lavagne, P, Lepoivre, T, Moussa, M, Vieillard-Baron, A, Durand, M, Gainnier, M, Ichai, C, Arens, S, Hoffmann, C, Kaffarnik, M, Scharnofske, C, Voigt, I, Peckelsen, C, Weber, M, Gille, J, Lange, A, Schoser, G, Sablotzki, A, Bluethgen, A, Vogel, F, Tscheu, A, Fuchs, T, Wattenberg, M, Helmes, T, Scieszka, S, Heintz, M, Sakka, S, Kohler, J, Fiedler, F, Danz, M, Riessen, R, Kerz, T, Kersten, A, Tacke, F, Marx, G, Volkert, T, Schmutz, A, Nierhaus, A, Kluge, S, Abel, P, Janosi, R, Utzolino, S, Bracht, H, Toussaint, S, Peftoulidou, M, Myrianthefs, P, Armaganidis, A, Routsi, C, Xini, A, Mouloudi, E, Kokoris, I, Kyriazopoulos, G, Vlachos, S, Lavrentieva, A, Partala, P, Nakos, G, Moller, A, Stefansson, S, Barry, J, O'Leary, R, Motherway, C, Faheem, M, Dunne, E, Donnelly, M, Konrad, T, Bonora, E, Achilli, C, Rossi, S, Castiglione, G, Peris, A, Albanese, D, Stocchetti, N, Citerio, G, Mozzoni, L, Sisillo, E, De Negri, P, Savioli, M, Vecchiarelli, P, Puflea, F, Stankovic, V, Minoja, G, Montibeller, S, Calligaro, P, Sorrentino, R, Feri, M, Zambon, M, Colombaroli, E, Giarratano, A, Pellis, T, Capra, C, Antonelli, M, Gullo, A, Chelazzi, C, De Capraris, A, Patroniti, N, Girardis, M, Franchi, F, Berlot, G, Buttigieg, M, Ponssen, H, Ten Cate, J, Bormans, L, Husada, S, Buise, M, Van Der Hoven, B, Reidinga, A, Kuiper, M, Kluge, G, Den Boer, S, Kesecioglu, J, Van Leeuwen, H, Flaatten, H, Mo, S, Branco, V, Rua, F, Lafuente, E, Sousa, M, Catorze, N, Barros, M, Pereira, L, De Oliveira, A, Gomes, J, Gaspar, I, Pereira, M, Cymbron, M, Dias, A, Almeida, E, Beirao, S, Serra, I, Ribeiro, R, Povoa, P, Faria, F, Costa-E-Silva, Z, Nobrega, J, Fernandes, F, Gabriel, J, Voga, G, Rupnik, E, Kosec, L, Povsic, M, Osojnik, I, Tomic, V, Sinkovic, A, Gonzalez, J, Zavala, E, Valenzuela, J, Marina, L, Vidal-Cortes, P, Posada, P, Martin-Loeches, I, Guillen, N, Palomar, M, Sole-Violan, J, Torres, A, Gonzalez Gallego, M, Aguilar, G, Allue, R, Argueso, M, Parejo, M, Navarro, M, Jose, A, Nin, N, Lerma, F, Martinez, O, Lozano, E, Lopez, S, Perez Granda, M, Moreno, S, Llubia, C, Martos, C, Gonzalez-Arenas, P, Fernandez, N, Rueda, B, Pons, I, Cruza, N, Maroto, F, Estella, A, Ferrer, A, Fraile, L, Quindos, B, Quintano, A, Tebar, M, Cardinal, P, Reyes, A, Rodriguez, A, Abella, A, Del Valle, S, Yus, S, Maseda, E, Berezo, J, Pedregosa, A, Laplaza, C, Ferrer, R, Rico-Feijoo, J, Rodriguez, M, Monedero, P, Eriksson, K, Lind, D, Chabanel, D, Zender, H, Heer, K, Frankenberger, B, Haller, A, Matthew, S, Downes, R, Groba, C, Johnston, A, Meacher, R, Keays, R, Haji-Michael, P, Tyler, C, Jones, S, Tyl, D, Ball, A, Vogel, J, Booth, M, Downie, P, Watters, M, Brett, S, Garfield, M, Everett, L, Heenen, S, Dhir, S, Beardow, Z, Mostert, M, Brosnan, S, Pinto, N, Harris, S, Summors, A, Norton, A, Rose, A, Appelboam, R, Davies, O, Vickers, E, Agarwal, B, Szakmany, T, Wimbush, S, Welters, I, Pearse, R, Hollands, R, Kirk-Bayley, J, Fletcher, N, Bray, B, Brealey, D, Alexander, P, Henderson, S, Hargreaves, C, Black, H, Gowda, K, Vincent J. -L., Ferguson A., Pickkers P., Jakob S. M., Jaschinski U., Almekhlafi G. A., Leone M., Mokhtari M., Fontes L. E., Bauer P. R., Sakr Y., Tomas E., Bibonge E. A., Charra B., Faroudy M., Doedens L., Farina Z., Adler D., Balkema C., Kok A., Alaya S., Gharsallah H., Muzha D., Temelkov A., Georgiev G., Simeonov G., Tsaryanski G., Georgiev S., Seliman A., Vrankovic S., Vucicevic Z., Gornik I., Barsic B., Husedzinovic I., Pavlik P., Manak J., Kieslichova E., Turek R., Fischer M., Valkova R., Dadak L., Dostal P., Malaska J., Hajek R., Zidkova A., Lavicka P., Starkopf J., Kheladze Z., Chkhaidze M., Kaloiani V., Medve L., Sarkany A., Kremer I., Marjanek Z., Tamasi P., Krupnova I., Vanags I., Liguts V., Pilvinis V., Vosylius S., Kekstas G., Balciunas M., Kolbusz J., Kubler A., Mielczarek B., Mikaszewska-Sokolewicz M., Kotfis K., Tamowicz B., Sulkowski W., Smuszkiewicz P., Pihowicz A., Trejnowska E., Hagau N., Filipescu D., Droc G., Lupu M. N., Nica A., Stoica R., Tomescu D. R., Constantinescu D. L., Valcoreanu Zbaganu G. M., Slavcovici A., Bagin V., Belsky D., Palyutin S., Shlyapnikov S., Bikkulova D., Gritsan A., Natalia G., Makarenko E., Kokhno V., Tolkach A., Kokarev E., Belotserkovskiy B., Zolotukhin K., Kulabukhov V., Soskic L., Palibrk I., Jankovic R., Jovanovic B., Pandurovic M., Bumbasirevic V., Uljarevic B., Surbatovic M., Ladjevic N., Slobodianiuk G., Sobona V., Cikova A., Gebhardtova A., Jun C., Yunbo S., Dong J., Feng S., Duan M., Xu Y., Xue X., Gao T., Xing X. Z., Zhao X., Li C. H., Gengxihua G., Tan H., Xu J., Jiang L., Tiehe Q., Bingyu Q., Shi Q., Lv Z., Zhang L., Jingtao L., Zhen Z., Wang Z., Wang T. H., Yuhong L., Zhai Q., Chen Y., Wang C., Jiang W., Ruilan W., Xiaobo H., Ge H., Yan T., Yuhui C., Zhang J., Jian-Hong F., Zhu H., Huo F., Wang Y., Li C., Zhuang M., Ma Z., Sun J., Liuqingyue L., Yang M., Meng J., Ma S., Kang Y., Yu L., Peng Q., Wei Y., Zhang W., Sun R., Yeung A., Wan W. L., Sin K. K. C., Lee K. L., Wijanti M., Widodo U., Samsirun H., Sugiman T., Wisudarti C., Maskoen T. T., Hata N., Kobe Y., Nishida O., Miyazaki D., Nunomiya S., Uchino S., Kitamura N., Yamashita K., Hashimoto S., Fukushima H., Adib N. A. N., Tai L. L., Tony B., Bigornia R. R., Palo J. E., Chatterjee S., Tan B. H., Kong A., Goh S., Lee C. -C., Pothirat C., Khwannimit B., Theerawit P., Pornsuriyasak P., Piriyapatsom A., Mukhtar A., Hamdy A. N., Hosny H., Ashraf A., Nowruzinia S., Lotfi A. H., Zand F., Nikandish R., Moghaddam O. M., Cohen J., Sold O., Sfeir T., Hasan A. Y., Abugaber D., Ahmad H., Tantawy T., Baharoom S., Algethamy H., Amr A., Almekhlafi G., Coskun R., Sungur M., Cosar A., Gucyetmez B., Demirkiran O., Senturk E., Ulusoy H., Atalan H. K., Serin S., Kati I., Alnassrawi Z., Almemari A., Krishnareddy K., Kashef S., Alsabbah A., Poirier G., Marshall J. C., Herridge M., Fernandez-Medero R., Fulda G., Banschbach S., Quintero J., Schroeder E., Sicoutris C., Gueret R., Kashyap R., Bauer P., Nanchal R., Wunderink R. G., Jimenez E., Ryan A., Prince D., Edington J., Van Haren F., Bersten A., Hawkins D. J., Kilminster M., Sturgess D., Ziegenfuss M., O' Connor S., Lipman J., Campbell L., McAllister R., Roberts B., Williams P., Parke R., Seigne P., Freebairn R., Nistor D., Oxley C., Young P., Valentini R., Wainsztein N., Comignani P., Casaretto M., Sutton G., Villegas P., Galletti C., Neira J., Rovira D., Hidalgo J., Sandi F., Caser E., Thompson M. M., D'Agostino Dias M., Lunardi M. C., Youssef N. C., Lobo S., Silva R., Sales J. A., Melo L. M. C., Oliveira M., Fonte M., Grion C., Feijo C., Rezende V., Assuncao M., Neves A. P., Gusman P., Dalcomune D., Teixeira C., Kaefer K., Maia I., Dantas V. S., Filho R. C., Amorim F., Assef M., Schiavetto P., Houly J., Bianchi F., Dias F., Avila C., Rego L., Castro P., Passos J., Mendes C., Mecatti G. C., Ferrreira M., Irineu V., Guerreiro M., Ugarte S., Tomicic V., Godoy C., Samaniego W., Escamilla I., Castro Castro L. F., Duque G. L., Diaz-Guio D., Benitez F., Urrego A. G., Buitrago R., Ortiz G., Villalba Gaviria M. C., Salas D., Ramirez-Arce J., Salgado E., Morocho D., Vergara J., Sang M. C., Orellana-Jimenez C., Garrido L., Diaz O., Resiere D., Osorio C., De La Vega A., Carrillo R., Sanchez V., Villagomez A., Zubieta R. M., Sandia M., Zalatiel M., Poblano M., Gonzalez D. R., Arrazola F., Juan Francisco L. L., Namendys-Silva S. A., Moya R. G., Hernandez M., Rodriguez Cadena D. M., Islas I. L., Ballesteros Zarzavilla C. M., Matos A., Oyanguren I., Cerna J., Sierra R. Q., Jimenez R., Castillo L., Ocal R., Sencan A., Mareque Gianoni S. M., Deicas A., Hurtado J., Burghi G., Martinelli A., Von Der Osten I., Du Maine C., Bhattacharyya M., Bandyopadhyay S., Yanamala S., Gopal P., Sahu S., Ibrahim M., Rathod D., Mukundan N., Dewan A., Amin P., Samavedam S., Shah B., Gurupal G., Lahkar B., Mandal A. K., Sircar M., Ghosh S., Balasubramani V., Kapadia F., Vadi S., Nair K., Tripathy S., Nandakumar S., Sharma J., Kar A., Jha S., Zirpe K., Patel M., Bhavsar A., Samaddar D. P., Kulkarni A., Hashmi M., Ali W., Nadeem S., Indraratna K., Margarit A., Urbanek P., Schlieber J., Reisinger J., Auer J., Hartjes A., Lerche A., Janous T., Kink E., Krahulec W., Smolle K. -H., Van Der Schueren M., Thibo P., Vanhoof M., Ahmet I., Gadisseux P., Dufaye P., Jacobs O., Fraipont V., Biston P., Dive A., Bouckaert Y., Gilbert E., Gressens B., Pinck E., Collin V., De Waele J. J., Rimachi R., Gusu D., De Decker K., Mandianga K., Heytens L., Wittebole X., Spapen H., Van Collie O., Vandenheede W., Rogiers P., Kolodzeike P., Kruse M., Andersen T., Harjola V. -P., Saarinen K., Durocher A., Moulront S., Lepape A., Losser M. -R., Cabaret P., Kalaitzis E., Zogheib E., Charve P., Francois B., Lefrant J. -Y., Beilouny B., Forceville X., Misset B., Jacobs F., Floccard B., Payen D., Wynckel A., Castelain V., Faure A., Lavagne P., Lepoivre T., Moussa M. D., Vieillard-Baron A., Durand M., Gainnier M., Ichai C., Arens S., Hoffmann C., Kaffarnik M., Scharnofske C. -J., Voigt I., Peckelsen C., Weber M., Gille J., Lange A., Schoser G., Sablotzki A., Bluethgen A., Vogel F., Tscheu A., Fuchs T., Wattenberg M., Helmes T., Scieszka S., Heintz M., Sakka S., Kohler J., Fiedler F., Danz M., Riessen R., Kerz T., Kersten A., Tacke F., Marx G., Volkert T., Schmutz A., Nierhaus A., Kluge S., Abel P., Janosi R. A., Utzolino S., Bracht H., Toussaint S., Peftoulidou M. G., Myrianthefs P., Armaganidis A., Routsi C., Xini A., Mouloudi E., Kokoris I., Kyriazopoulos G., Vlachos S., Lavrentieva A., Partala P., Nakos G., Moller A., Stefansson S. O., Barry J., O'Leary R. A., Motherway C., Faheem M., Dunne E., Donnelly M., Konrad T., Bonora E., Achilli C., Rossi S., Castiglione G., Peris A., Albanese D., Stocchetti N., Citerio G., Mozzoni L., Sisillo E., De Negri P., Savioli M., Vecchiarelli P., Puflea F., Stankovic V., Minoja G., Montibeller S., Calligaro P., Sorrentino R., Feri M., Zambon M., Colombaroli E., Giarratano A., Pellis T., Capra C., Antonelli M., Gullo A., Chelazzi C., De Capraris A., Patroniti N., Girardis M., Franchi F., Berlot G., Buttigieg M., Ponssen H., Ten Cate J., Bormans L., Husada S., Buise M., Van Der Hoven B., Reidinga A., Kuiper M., Kluge G., Den Boer S., Kesecioglu J., Van Leeuwen H., Flaatten H., Mo S., Branco V., Rua F., Lafuente E., Sousa M., Catorze N., Barros M., Pereira L., De Oliveira A. V., Gomes J., Gaspar I., Pereira M. F., Cymbron M., Dias A., Almeida E., Beirao S., Serra I., Ribeiro R., Povoa P., Faria F., Costa-E-Silva Z., Nobrega J. J., Fernandes F., Gabriel J., Voga G., Rupnik E., Kosec L., Povsic M. K., Osojnik I., Tomic V., Sinkovic A., Gonzalez J., Zavala E., Valenzuela J. P., Marina L., Vidal-Cortes P., Posada P., Martin-Loeches I., Guillen N. M., Palomar M., Sole-Violan J., Torres A., Gonzalez Gallego M. A., Aguilar G., Allue R. M., Argueso M., Parejo M., Navarro M. P., Jose A., Nin N., Lerma F. A., Martinez O., Lozano E. T., Lopez S. A., Perez Granda M. J., Moreno S., Llubia C., Martos C. D. L. F., Gonzalez-Arenas P., Fernandez N. L., Rueda B. G., Pons I. E., Cruza N., Maroto F., Estella A., Ferrer A., Fraile L. I., Quindos B., Quintano A., Tebar M. T., Cardinal P., Reyes A., Rodriguez A., Abella A., Del Valle S. G., Yus S., Maseda E., Berezo J. A., Pedregosa A. T., Laplaza C., Ferrer R., Rico-Feijoo J., Rodriguez M., Monedero P., Eriksson K., Lind D., Chabanel D., Zender H., Heer K., Frankenberger B., Jakob S., Haller A., Matthew S., Downes R., Groba C. B., Johnston A., Meacher R., Keays R., Haji-Michael P., Tyler C., Jones S., Tyl D., Ball A., Vogel J., Booth M., Downie P., Watters M., Brett S., Garfield M., Everett L., Heenen S., Dhir S., Beardow Z., Mostert M., Brosnan S., Pinto N., Harris S., Summors A., Norton A., Rose A., Appelboam R., Davies O., Vickers E., Agarwal B., Szakmany T., Wimbush S., Welters I., Pearse R., Hollands R., Kirk-Bayley J., Fletcher N., Bray B., Brealey D., Alexander P., Henderson S., Hargreaves C., Black H., Gowda K, and Citerio G
- Abstract
Background: Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients. Using a large multinational database, we therefore evaluated the occurrence of oliguria (defined as a urine output < 0.5 ml/kg/h) in acutely ill patients and its association with the need for renal replacement therapy (RRT) and outcome. Methods: International observational study. All adult (> 16 years) patients in the ICON audit who had a urine output measurement on the day of admission were included. To investigate the association between oliguria and mortality, we used a multilevel analysis. Results: Of the 8292 patients included, 2050 (24.7%) were oliguric during the first 24 h of admission. Patients with oliguria on admission who had at least one additional 24-h urine output recorded during their ICU stay (n = 1349) were divided into three groups: transient - oliguria resolved within 48 h after the admission day (n = 390 [28.9%]), prolonged - oliguria resolved > 48 h after the admission day (n = 141 [10.5%]), and permanent - oliguria persisting for the whole ICU stay or again present at the end of the ICU stay (n = 818 [60.6%]). ICU and hospital mortality rates were higher in patients with oliguria than in those without, except for patients with transient oliguria who had significantly lower mortality rates than non-oliguric patients. In multilevel analysis, the need for RRT was associated with a significantly higher risk of death (OR = 1.51 [95% CI 1.19-1.91], p = 0.001), but the presence of oliguria on admission was not (OR = 1.14 [95% CI 0.97-1.34], p = 0.103). Conclusions: Oliguria is common in ICU patients and may have a relatively benign nature if only transient. The duration of oliguria and need for RRT are associated with worse outcome.
- Published
- 2020