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2. Simple model for the fracture of a polymer chain: Single-bond potential of mean force and tension-based rate constants for chain rupture.
- Author
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Theodorou, D. N.
- Subjects
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FRACTURE mechanics , *STATE bonds , *CHEMICAL bond lengths , *REFORMATION , *EQUILIBRIUM - Abstract
A linear chain of N particles connected by Morse bonds with periodic boundaries in a Brownian bath is considered as a model for polymer fracture. The potential of mean force (pomf) with respect to the length of a bond and its energy and entropic components are computed via Langevin Dynamics simulations at various chain elongations λ > 1. A narrow range of λ values is identified over which equilibrium is established between an intact (i) and a fractured (f) state over a pomf barrier. While the barrier and (f) regions of the pomf are well described by a well-known (N − 1)-bond adiabatic approximation, the shape of the (i) region departs from it, exhibiting a bimodal character. A new, 1-bond adiabatic approximation is proposed to explain this. The lower envelope of the two adiabatic approximations provides an excellent description of the pomf. The relationship between (f) states for individual bonds and for the entire chain is elucidated. A new approach, based on analysis of equilibrium tension autocorrelation functions, is developed to extract rate constants for the fracture and reformation of the chain in dependence of λ. Results from it agree with tension relaxation during nonequilibrium simulations initiated at equispaced configurations of the particles. Rate constants for chain fracture conform to a Boltzmann–Arrhenius–Zhurkov dependence on the tension averaged over the intact state of the chain, the activation length being higher than estimated from pomf extrema. These findings constitute a step toward a predictive multiscale simulation scheme for fracture in polymeric materials. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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3. Predictors of anastomotic leak and conduit necrosis after oesophagectomy: Results from the oesophago-gastric anastomosis audit (OGAA)
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Halle-Smith, J.M., Kamarajah, S.K., Evans, R.P.T., Nepogodiev, D., Hodson, J., Bundred, J.R., Gockel, I., Gossage, J.A., Isik, A., Kauppila, J.H., Kidane, B., Mahendran, H.A., Negoi, I., Okonta, K.E., Sayyed, R., van Hillegersberg, R., Vohra, R.S., Wijnhoven, B.P.L., Singh, P., Griffiths, E.A., Alderson, D., Bundred, J., Gossage, J., Jefferies, B., McKay, S., Mohamed, I., Siaw- Acheampong, K., Vohra, R., Wanigasooriya, K., Whitehouse, T., Gjata, A., Moreno, J.I., Takeda, F.R., Guevara Castro, R., Bekele, A., Harustiak, T., Kechagias, A., Bagajevas, A., Kennedy, A., Da Roit, A., Azagra, J.S., Mejía-Fernández, L., El Kafsi, J., Sayyed, R.H., Sousa, M., Sampaio, A.S., Blanco, R., Wallner, B., Schneider, P.M., Hsu, P.K., Gananadha, S., Wills, V., Devadas, M., Duong, C., Talbot, M., Hii, M.W., Jacobs, R., Andreollo, N.A., Johnston, B., Darling, G., Isaza-Restrepo, A., Rosero, G., Arias- Amézquita, F., Raptis, D., Gaedcke, J., Reim, D., Izbicki, J., Egberts, J.H., Dikinis, S., Kjaer, D.W., Larsen, M.H., Achiam, M.P., Saarnio, J., Theodorou, D., Liakakos, T., Korkolis, D.P., Robb, W.B., Collins, C., Murphy, T., Reynolds, J., Tonini, V., Migliore, M., Bonavina, L., Valmasoni, M., Bardini, R., Weindelmayer, J., Terashima, M., White, R.E., Alghunaim, E., Elhadi, M., Leon-Takahashi, A.M., Medina-Franco, H., Lau, P.C., Heisterkamp, J., Rosman, C., Beban, G., Babor, R., Gordon, A., Rossaak, J.I., Pal, K.M.I., Qureshi, A.U., Naqi, S.A., Syed, A.A., Barbosa, J., Vicente, C.S., Leite, J., Freire, J., Casaca, R., Costa, R.C.T., Scurtu, R.R., Mogoanta, S.S., Bolca, C., Constantinoiu, S., Sekhniaidze, D., Bjelović, M., So, J.B.Y., Gačevski, G., Loureiro, C., Pera, M., Bianchi, A., Moreno Gijón, M., Martín Fernández, J., Trugeda Carrera, M.S., Vallve-Bernal, M., Cítores Pascual, M.A., Elmahi, S., Halldestam, I., Hedberg, J., Mönig, S., Gutknecht, S., Tez, M., Guner, A., Tirnaksiz, M.B., Colak, E., Sevinç, B., Hindmarsh, A., Khan, I., Khoo, D., Byrom, R., Gokhale, J., Wilkerson, P., Jain, P., Chan, D., Robertson, K., Iftikhar, S., Skipworth, R., Forshaw, M., Higgs, S., Nijjar, R., Viswanath, Y.K.S., Turner, P., Dexter, S., Boddy, A., Allum, W.H., Oglesby, S., Cheong, E., Beardsmore, D., Maynard, N., Berrisford, R., Mercer, S., Puig, S., Melhado, R., Kelty, C., Underwood, T., Dawas, K., Lewis, W., Al-Bahrani, A., Bryce, G., Thomas, M., Arndt, A.T., Palazzo, F., Meguid, R.A., Fergusson, J., Beenen, E., Mosse, C., Salim, J., Cheah, S., Wright, T., Cerdeira, M.P., McQuillan, P., Richardson, M., Liem, H., Spillane, J., Yacob, M., Albadawi, F., Thorpe, T., Dingle, A., Cabalag, C., Loi, K., Fisher, O.M., Ward, S., Read, M., Johnson, M., Bassari, R., Bui, H., Cecconello, I., Sallum, R.A.A., da Rocha, J.R.M., Lopes, L.R., Tercioti, V., Coelho, J.D.S., Ferrer, J.A.P., Buduhan, G., Tan, L., Srinathan, S., Shea, P., Yeung, J., Allison, F., Carroll, P., Vargas-Barato, F., Gonzalez, F., Ortega, J., Nino-Torres, L., Beltrán-García, T.C., Castilla, L., Pineda, M., Bastidas, A., Gómez-Mayorga, J., Cortés, N., Cetares, C., Caceres, S., Duarte, S., Pazdro, A., Snajdauf, M., Faltova, H., Sevcikova, M., Mortensen, P.B., Katballe, N., Ingemann, T., Morten, B., Kruhlikava, I., Ainswort, A.P., Stilling, N.M., Eckardt, J., Holm, J., Thorsteinsson, M., Siemsen, M., Brandt, B., Nega, B., Teferra, E., Tizazu, A., Koivukangas, V., Meriläinen, S., Gruetzmann, R., Krautz, C., Weber, G., Golcher, H., Emons, G., Azizian, A., Ebeling, M., Niebisch, S., Kreuser, N., Albanese, G., Hesse, J., Volovnik, L., Boecher, U., Reeh, M., Triantafyllou, S., Schizas, D., Michalinos, A., Balli, E., Mpoura, M., Charalabopoulos, A., Manatakis, D.K., Balalis, D., Bolger, J., Baban, C., Mastrosimone, A., McAnena, O., Quinn, A., Ó Súilleabháin, C.B., Hennessy, M.M., Ivanovski, I., Khizer, H., Ravi, N., Donlon, N., Cervellera, M., Vaccari, S., Bianchini, S., Sartarelli, l, Asti, E., Bernardi, D., Merigliano, S., Provenzano, L., Scarpa, M., Saadeh, L., Salmaso, B., De Manzoni, G., Giacopuzzi, S., La Mendola, R., De Pasqual, C.A., Tsubosa, Y., Niihara, M., Irino, T., Makuuchi, R., Ishii, K., Mwachiro, M., Fekadu, A., Odera, A., Mwachiro, E., AlShehab, D., Ahmed, H.A., Shebani, A.O., Elhadi, A., Elnagar, F.A., Elnagar, H.F., Makkai-Popa, S.T., Wong, L.F., Yr, Tan, S, Thannimalai, Ca, Ho, Ws, Pang, Jh, Tan, Hnl, Basave, Cortés-González, R., Lagarde, S.M., van Lanschot, J.J.B., Cords, C., Jansen, W.A., Martijnse, I., Matthijsen, R., Bouwense, S., Klarenbeek, B., Verstegen, M., van Workum, F., Ruurda, J.P., van der Sluis, P.C., de Maat, M., Evenett, N., Johnston, P., Patel, R., MacCormick, A., Young, M., Smith, B., Ekwunife, C., Memon, A.H., Shaikh, K., Wajid, A., Khalil, N., Haris, M., Mirza, Z.U., Qudus, S.B.A., Sarwar, M.Z., Shehzadi, A., Raza, A., Jhanzaib, M.H., Farmanali, J., Zakir, Z., Shakeel, O., Nasir, I., Khattak, S., Baig, M., Noor, M.A., Ahmed, H.H., Naeem, A., Pinho, A.C., da Silva, R., Bernardes, A., Campos, J.C., Matos, H., Braga, T., Monteiro, C., Ramos, P., Cabral, F., Gomes, M.P., Martins, P.C., Correia, A.M., Videira, J.F., Ciuce, C., Drasovean, R., Apostu, R., Paitici, S., Racu, A.E., Obleaga, C.V., Beuran, M., Stoica, B., Ciubotaru, C., Negoita, V., Cordos, I., Birla, R.D., Predescu, D., Hoara, P.A., Tomsa, R., Shneider, V., Agasiev, M., Ganjara, I., Gunjić, D., Veselinović, M., Babič, T., Chin, T.S., Shabbir, A., Kim, G., Crnjac, A., Samo, H., Díez del Val, I., Leturio, S., Ramón, J.M., Dal Cero, M., Rifá, S., Rico, M., Pagan Pomar, A., Martinez Corcoles, J.A., Rodicio Miravalles, J.L., Pais, S.A., Turienzo, S.A., Alvarez, L.S., Campos, P.V., Rendo, A.G., García, S.S., Santos, E.P.G., Martínez, E.T., Fernández Díaz, M.J., Magadán Álvarez, C., Concepción Martín, V., Díaz López, C., Rosat Rodrigo, A., Pérez Sánchez, L.E., Bailón Cuadrado, M., Tinoco Carrasco, C., Choolani Bhojwani, E., Sánchez, D.P., Ahmed, M.E., Dzhendov, T., Lindberg, F., Rutegård, M., Sundbom, M., Mickael, C., Colucci, N., Schnider, A., Er, S., Kurnaz, E., Turkyilmaz, S., Turkyilmaz, A., Yildirim, R., Baki, B.E., Akkapulu, N., Karahan, O., Damburaci, N., Hardwick, R., Safranek, P., Sujendran, V., Bennett, J., Afzal, Z., Shrotri, M., Chan, B., Exarchou, K., Gilbert, T., Amalesh, T., Mukherjee, D., Mukherjee, S., Wiggins, T.H., Kennedy, R., McCain, S., Harris, A., Dobson, G., Davies, N., Wilson, I., Mayo, D., Bennett, D., Young, R., Manby, P., Blencowe, N., Schiller, M., Byrne, B., Mitton, D., Wong, V., Elshaer, A., Cowen, M., Menon, V., Tan, L.C., McLaughlin, E., Koshy, R., Sharp, C., Brewer, H., Das, N., Cox, M., Al Khyatt, W., Worku, D., Iqbal, R., Walls, L., McGregor, R., Fullarton, G., Macdonald, A., MacKay, C., Craig, C., Dwerryhouse, S., Hornby, S., Jaunoo, S., Wadley, M., Baker, C., Saad, M., Kelly, M., Davies, A., Di Maggio, F., Mistry, P., Singhal, R., Tucker, O., Kapoulas, S., Powell-Brett, S., Davis, P., Bromley, G., Watson, L., Verma, R., Ward, J., Shetty, V., Ball, C., Pursnani, K., Sarela, A., Sue Ling, H., Mehta, S., Hayden, J., To, N., Palser, T., Hunter, D., Supramaniam, K., Butt, Z., Ahmed, A., Kumar, S., Chaudry, A., Moussa, O., Kordzadeh, A., Lorenzi, B., Wilson, M., Patil, P., Noaman, I., Willem, J., Bouras, G., Evans, R., Singh, M., Warrilow, H., Ahmad, A., Tewari, N., Yanni, F., Couch, J., Theophilidou, E., Reilly, J.J., van Boxel, Gijs, Akbari, K., Zanotti, D., Sgromo, B., Sanders, G., Wheatley, T., Ariyarathenam, A., Reece-Smith, A., Humphreys, L., Choh, C., Carter, N., Knight, B., Pucher, P., Athanasiou, A., Tan, B., Abdulrahman, M., Vickers, J., Akhtar, K., Chaparala, R., Brown, R., Alasmar, M.M.A., Ackroyd, R., Patel, K., Tamhankar, A., Wyman, A., Walker, R., Grace, B., Abbassi, N., Slim, N., Ioannidi, L., Blackshaw, G., Havard, T., Escofet, X., Powell, A., Owera, A., Rashid, F., Jambulingam, P., Padickakudi, J., Ben-Younes, H., Mccormack, K., Makey, I.A., Karush, M.K., Seder, C.W., Liptay, M.J., Chmielewski, G., Rosato, E.L., Berger, A.C., Zheng, R., Okolo, E., Singh, A., Scott, C.D., Weyant, M.J., Mitchell, J.D., and Griffiths, Ewen A.
- Published
- 2024
- Full Text
- View/download PDF
4. Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago
- Author
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Perrone, G, Giuffrida, M, Abu-Zidan, F, Kruger, V, Livrini, M, Petracca, G, Rossi, G, Tarasconi, A, Tian, B, Bonati, E, Mentz, R, Mazzini, F, Campana, J, Gasser, E, Kafka-Ritsch, R, Felsenreich, D, Dawoud, C, Riss, S, Gomes, C, Gomes, F, Gonzaga, R, Canton, C, Pereira, B, Fraga, G, Zem, L, Cordeiro-Fonseca, V, de Mesquita Tauil, R, Atanasov, B, Belev, N, Kovachev, N, Melendez, L, Dimova, A, Dimov, S, Zelic, Z, Augustin, G, Bogdanic, B, Moric, T, Chouillard, E, Bajul, M, De Simone, B, Panis, Y, Esposito, F, Notarnicola, M, Lauka, L, Fabbri, A, Hentati, H, Fnaiech, I, Aurelien, V, Bougard, M, Roulet, M, Demetrashvili, Z, Pipia, I, Merabishvili, G, Bouliaris, K, Koukoulis, G, Doudakmanis, C, Xenaki, S, Chrysos, E, Kokkinakis, S, Vassiliu, P, Michalopoulos, N, Margaris, I, Kechagias, A, Avgerinos, K, Katunin, J, Lostoridis, E, Nagorni, E, Pujante, A, Mulita, F, Maroulis, I, Vailas, M, Marinis, A, Siannis, I, Bourbouteli, E, Manatakis, D, Tasis, N, Acheimastos, V, Maria, S, Stylianos, K, Kuzeridis, H, Korkolis, D, Fradelos, E, Kavalieratos, G, Petropoulou, T, Polydorou, A, Papacostantinou, I, Triantafyllou, T, Kimpizi, D, Theodorou, D, Toutouzas, K, Chamzin, A, Frountzas, M, Schizas, D, Karavokyros, I, Syllaios, A, Charalabopoulos, A, Boura, M, Baili, E, Ioannidis, O, Loutzidou, L, Anestiadou, E, Tsouknidas, I, Petrakis, G, Polenta, E, Bains, L, Gupta, R, Singh, S, Khanduri, A, Bala, M, Kedar, A, Pisano, M, Podda, M, Pisanu, A, Martines, G, Trigiante, G, Lantone, G, Agrusa, A, Di Buono, G, Buscemi, S, Veroux, M, Gioco, R, Veroux, G, Oragano, L, Zonta, S, Lovisetto, F, Feo, C, Pesce, A, Fabbri, N, Marino, F, Perrone, F, Vincenti, L, Papagni, V, Picciariello, A, Rossi, S, Picardi, B, Del Monte, S, Visconti, D, Osella, G, Petruzzelli, L, Pignata, G, Andreuccetti, J, D'Alessio, R, Buonfantino, M, Guaitoli, E, Spinelli, S, Sampietro, G, Corbellini, C, Lorusso, L, Frontali, A, Pezzoli, I, Bonomi, A, Chierici, A, Cotsoglou, C, Manca, G, Delvecchio, A, Musa, N, Casati, M, Letizia, L, Abate, E, Ercolani, G, D'Acapito, F, Solaini, L, Guercioni, G, Cicconi, S, Sasia, D, Borghi, F, Giraudo, G, Sena, G, Castaldo, P, Cardamone, E, Portale, G, Zuin, M, Spolverato, Y, Esposito, M, Isernia, R, Di Salvo, M, Manunza, R, Esposito, G, Agus, M, Asti, E, Bernardi, D, Tonucci, T, Luppi, D, Casadei, M, Bonilauri, S, Pezzolla, A, Panebianco, A, Laforgia, R, De Luca, M, Zese, M, Parini, D, Jovine, E, De Sario, G, Lombardi, R, Aprea, G, Palomba, G, Capuano, M, Argenio, G, Orio, G, Armellino, M, Troian, M, Guerra, M, Nagliati, C, Biloslavo, A, Germani, P, Aizza, G, Monsellato, I, Chahrour, A, Anania, G, Bombardini, C, Bagolini, F, Sganga, G, Fransvea, P, Bianchi, V, Boati, P, Ferrara, F, Palmieri, F, Cianci, P, Gattulli, D, Restini, E, Cillara, N, Cannavera, A, Nita, G, Sarnari, J, Roscio, F, Clerici, F, Scandroglio, I, Berti, S, Cadeo, A, Filippelli, A, Conti, L, Grassi, C, Cattaneo, G, Pighin, M, Papis, D, Gambino, G, Bertino, V, Schifano, D, Prando, D, Fogato, L, Cavallo, F, Ansaloni, L, Picheo, R, Pontarolo, N, Depalma, N, Spampinato, M, D'Ugo, S, Lepre, L, Capponi, M, Campa, R, Sarro, G, Dinuzzi, V, Olmi, S, Uccelli, M, Ferrari, D, Inama, M, Moretto, G, Fontana, M, Favi, F, Picariello, E, Rampini, A, Barberis, A, Azzinnaro, A, Oliva, A, Totaro, L, Benzoni, I, Ranieri, V, Capolupo, G, Carannante, F, Caricato, M, Ronconi, M, Casiraghi, S, Casole, G, Pantalone, D, Alemanno, G, Scheiterle, M, Ceresoli, M, Cereda, M, Fumagalli, C, Zanzi, F, Bolzon, S, Guerra, E, Lecchi, F, Cellerino, P, Ardito, A, Scaramuzzo, R, Balla, A, Lepiane, P, Tartaglia, N, Ambrosi, A, Pavone, G, Palini, G, Veneroni, S, Garulli, G, Ricci, C, Torre, B, Russo, I, Rottoli, M, Tanzanu, M, Belvedere, A, Milone, M, Manigrasso, M, De Palma, G, Piccoli, M, Pattacini, G, Magnone, S, Bertoli, P, Massucco, P, Palisi, M, Luzzi, A, Fleres, F, Clarizia, G, Spolini, A, Kobe, Y, Toma, T, Shimamura, F, Parker, R, Ranketi, S, Mitei, M, Svagzdys, S, Pauzas, H, Zilinskas, J, Poskus, T, Kryzauskas, M, Jakubauskas, M, Zakaria, A, Zakaria, Z, Wong, M, Jusoh, A, Zakaria, M, Cruz, D, Elizalde, A, Reynaud, A, Hernandez, E, Monroy, J, Hinojosa-Ugarte, D, Quiodettis, M, Du Bois, M, Latorraca, J, Major, P, Pedziwiatr, M, Pisarska-Adamczyk, M, Waledziak, M, Kwiatkowski, A, Czyzykowski, L, da Costa, S, Ferreira, A, Almeida, F, Rocha, R, Carneiro, C, Perez, D, Carvas, J, Rocha, C, Ferreira, C, Marques, R, Fernandes, U, Leao, P, Goulart, A, Pereira, R, Patrocinio, S, de Mendonca, N, Manso, M, Morais, H, Cardoso, P, Calu, V, Miron, A, Toma, E, Gachabayov, M, Abdullaev, A, Litvin, A, Nechay, T, Tyagunov, A, Yuldashev, A, Bradley, A, Wilson, M, Panyko, A, Lateckova, Z, Lacko, V, Lesko, D, Soltes, M, Radonak, J, Turrado-Rodriguez, V, Termes-Serra, R, Morales-Sevillano, X, Lapolla, P, Mingoli, A, Brachini, G, Degiuli, M, Sofia, S, Reddavid, R, de Manzoni Garberini, A, Buffone, A, del Pozo, E, Aparicio-Sanchez, D, Dos Barbeito, S, Estaire-Gomez, M, Viton-Herrero, R, de los Angeles Gil Olarte-Marquez, M, Gil-Martinez, J, Alconchel, F, Nicolas-Lopez, T, Rahy-Martin, A, Pelloni, M, Banolas-Suarez, R, Mendoza-Moreno, F, Nisa, F, Diez-Alonso, M, Rodas, M, Agundez, M, Andres, M, Moreira, C, Perez, A, Ponce, I, Gonzalez-Castillo, A, Membrilla-Fernandez, E, Salvans, S, Serradilla-Martin, M, Pardo, P, Rivera-Alonso, D, Dziakova, J, Huguet, J, Valle, N, Ruiz, E, Valcarcel, C, Moreno, C, Salazar, Y, Garcia, J, Mico, S, Lopez, J, Farre, S, Gomez, M, Petit, N, Titos-Garcia, A, Aranda-Narvaez, J, Romacho-Lopez, L, Sanchez-Guillen, L, Aranaz-Ostariz, V, Bosch-Ramirez, M, Martinez-Perez, A, Martinez-Lopez, E, Sebastian-Tomas, J, Jimenez-Riera, G, Jimenez-Vega, J, Cuellar, J, Campos-Serra, A, Munoz-Campana, A, Gracia-Roman, R, Alegre, J, Pinto, F, O'Sullivan, S, Antona, F, Jimenez, B, Lopez-Sanchez, J, Carmona, Z, Fernandez, R, Sierra, I, de Leon, L, Moreno, V, Iglesias, E, Cumplido, P, Bravo, A, Simo, I, Dominguez, C, Caamano, A, Lozano, R, Martinez, M, Torres, A, de Quiros, J, Pellino, G, Cloquell, M, Moller, E, Jalal-Eldin, S, Abdoun, A, Hamid, H, Lohsiriwat, V, Mongkhonsupphawan, A, Baraket, O, Ayed, K, Abbassi, I, Ali, A, Ammar, H, Kchaou, A, Tlili, A, Zribi, I, Colak, E, Polat, S, Koylu, Z, Guner, A, Usta, M, Reis, M, Mantoglu, B, Gonullu, E, Akin, E, Altintoprak, F, Bayhan, Z, Firat, N, Isik, A, Memis, U, Bayrak, M, Altintas, Y, Kara, Y, Bozkurt, M, Kocatas, A, Das, K, Seker, A, Ozer, N, Atici, S, Tuncer, K, Kaya, T, Ozkan, Z, Ilhan, O, Agackiran, I, Uzunoglu, M, Demirbas, E, Altinel, Y, Meric, S, Hacim, N, Uymaz, D, Omarov, N, Balik, E, Tebala, G, Khalil, H, Rana, M, Khan, M, Florence, C, Swaminathan, C, Leo, C, Liasis, L, Watfah, J, Trostchansky, I, Delgado, E, Pontillo, M, Latifi, R, Coimbra, R, Edwards, S, Lopez, A, Velmahos, G, Dorken, A, Gebran, A, Palmer, A, Oury, J, Bardes, J, Seng, S, Coffua, L, Ratnasekera, A, Egodage, T, Echeverria-Rosario, K, Armento, I, Napolitano, L, Sangji, N, Hemmila, M, Quick, J, Austin, T, Hyman, T, Curtiss, W, Mcclure, A, Cairl, N, Biffl, W, Truong, H, Schaffer, K, Reames, S, Banchini, F, Capelli, P, Coccolini, F, Sartelli, M, Bravi, F, Vallicelli, C, Agnoletti, V, Baiocchi, G, Catena, F, Perrone G., Giuffrida M., Abu-Zidan F., Kruger V. F., Livrini M., Petracca G. L., Rossi G., Tarasconi A., Tian B. W. C. A., Bonati E., Mentz R., Mazzini F. N., Campana J. P., Gasser E., Kafka-Ritsch R., Felsenreich D. M., Dawoud C., Riss S., Gomes C. A., Gomes F. C., Gonzaga R. A. T., Canton C. A. B., Pereira B. M., Fraga G. P., Zem L. G., Cordeiro-Fonseca V., de Mesquita Tauil R., Atanasov B., Belev N., Kovachev N., Melendez L. J. J., Dimova A., Dimov S., Zelic Z., Augustin G., Bogdanic B., Moric T., Chouillard E., Bajul M., De Simone B., Panis Y., Esposito F., Notarnicola M., Lauka L., Fabbri A., Hentati H., Fnaiech I., Aurelien V., Bougard M., Roulet M., Demetrashvili Z., Pipia I., Merabishvili G., Bouliaris K., Koukoulis G., Doudakmanis C., Xenaki S., Chrysos E., Kokkinakis S., Vassiliu P., Michalopoulos N., Margaris I., Kechagias A., Avgerinos K., Katunin J., Lostoridis E., Nagorni E. -A., Pujante A., Mulita F., Maroulis I., Vailas M., Marinis A., Siannis I., Bourbouteli E., Manatakis D. K., Tasis N., Acheimastos V., Maria S., Stylianos K., Kuzeridis H., Korkolis D., Fradelos E., Kavalieratos G., Petropoulou T., Polydorou A., Papacostantinou I., Triantafyllou T., Kimpizi D., Theodorou D., Toutouzas K., Chamzin A., Frountzas M., Schizas D., Karavokyros I., Syllaios A., Charalabopoulos A., Boura M., Baili E., Ioannidis O., Loutzidou L., Anestiadou E., Tsouknidas I., Petrakis G., Polenta E., Bains L., Gupta R., Singh S. K., Khanduri A., Bala M., Kedar A., Pisano M., Podda M., Pisanu A., Martines G., Trigiante G., Lantone G., Agrusa A., Di Buono G., Buscemi S., Veroux M., Gioco R., Veroux G., Oragano L., Zonta S., Lovisetto F., Feo C. V., Pesce A., Fabbri N., Marino F., Perrone F., Vincenti L., Papagni V., Picciariello A., Rossi S., Picardi B., Del Monte S. R., Visconti D., Osella G., Petruzzelli L., Pignata G., Andreuccetti J., D'Alessio R., Buonfantino M., Guaitoli E., Spinelli S., Sampietro G. M., Corbellini C., Lorusso L., Frontali A., Pezzoli I., Bonomi A., Chierici A., Cotsoglou C., Manca G., Delvecchio A., Musa N., Casati M., Letizia L., Abate E., Ercolani G., D'Acapito F., Solaini L., Guercioni G., Cicconi S., Sasia D., Borghi F., Giraudo G., Sena G., Castaldo P., Cardamone E., Portale G., Zuin M., Spolverato Y., Esposito M., Isernia R. M., Di Salvo M., Manunza R., Esposito G., Agus M., Asti E. L. G., Bernardi D. T., Tonucci T. P., Luppi D., Casadei M., Bonilauri S., Pezzolla A., Panebianco A., Laforgia R., De Luca M., Zese M., Parini D., Jovine E., De Sario G., Lombardi R., Aprea G., Palomba G., Capuano M., Argenio G., Orio G., Armellino M. F., Troian M., Guerra M., Nagliati C., Biloslavo A., Germani P., Aizza G., Monsellato I., Chahrour A. C., Anania G., Bombardini C., Bagolini F., Sganga G., Fransvea P., Bianchi V., Boati P., Ferrara F., Palmieri F., Cianci P., Gattulli D., Restini E., Cillara N., Cannavera A., Nita G. E., Sarnari J., Roscio F., Clerici F., Scandroglio I., Berti S., Cadeo A., Filippelli A., Conti L., Grassi C., Cattaneo G. M., Pighin M., Papis D., Gambino G., Bertino V., Schifano D., Prando D., Fogato L., Cavallo F., Ansaloni L., Picheo R., Pontarolo N., Depalma N., Spampinato M., D'Ugo S., Lepre L., Capponi M. G., Campa R. D., Sarro G., Dinuzzi V. P., Olmi S., Uccelli M., Ferrari D., Inama M., Moretto G., Fontana M., Favi F., Picariello E., Rampini A., Barberis A., Azzinnaro A., Oliva A., Totaro L., Benzoni I., Ranieri V., Capolupo G. T., Carannante F., Caricato M., Ronconi M., Casiraghi S., Casole G., Pantalone D., Alemanno G., Scheiterle M., Ceresoli M., Cereda M., Fumagalli C., Zanzi F., Bolzon S., Guerra E., Lecchi F., Cellerino P., Ardito A., Scaramuzzo R., Balla A., Lepiane P., Tartaglia N., Ambrosi A., Pavone G., Palini G. M., Veneroni S., Garulli G., Ricci C., Torre B., Russo I. S., Rottoli M., Tanzanu M., Belvedere A., Milone M., Manigrasso M., De Palma G. D., Piccoli M., Pattacini G. C., Magnone S., Bertoli P., Massucco P., Palisi M., Luzzi A. -P., Fleres F., Clarizia G., Spolini A., Kobe Y., Toma T., Shimamura F., Parker R., Ranketi S., Mitei M., Svagzdys S., Pauzas H., Zilinskas J., Poskus T., Kryzauskas M., Jakubauskas M., Zakaria A. D., Zakaria Z., Wong M. P. -K., Jusoh A. C., Zakaria M. N., Cruz D. R., Elizalde A. B. R., Reynaud A. B., Hernandez E. E. L., Monroy J. M. V. P., Hinojosa-Ugarte D., Quiodettis M., Du Bois M. E., Latorraca J., Major P., Pedziwiatr M., Pisarska-Adamczyk M., Waledziak M., Kwiatkowski A., Czyzykowski L., da Costa S. D., Pereira B., Ferreira A. R. O., Almeida F., Rocha R., Carneiro C., Perez D. P., Carvas J., Rocha C., Ferreira C., Marques R., Fernandes U., Leao P., Goulart A., Pereira R. G., Patrocinio S. D. D., de Mendonca N. G. G., Manso M. I. C., Morais H. M. C., Cardoso P. S., Calu V., Miron A., Toma E. A., Gachabayov M., Abdullaev A., Litvin A., Nechay T., Tyagunov A., Yuldashev A., Bradley A., Wilson M., Panyko A., Lateckova Z., Lacko V., Lesko D., Soltes M., Radonak J., Turrado-Rodriguez V., Termes-Serra R., Morales-Sevillano X., Lapolla P., Mingoli A., Brachini G., Degiuli M., Sofia S., Reddavid R., de Manzoni Garberini A., Buffone A., del Pozo E. P., Aparicio-Sanchez D., Dos Barbeito S., Estaire-Gomez M., Viton-Herrero R., de los Angeles Gil Olarte-Marquez M. a., Gil-Martinez J., Alconchel F., Nicolas-Lopez T., Rahy-Martin A. C., Pelloni M., Banolas-Suarez R., Mendoza-Moreno F., Nisa F. G. -M., Diez-Alonso M., Rodas M. E. V., Agundez M. C., Andres M. I. P., Moreira C. C. L., Perez A. L., Ponce I. A., Gonzalez-Castillo A. M., Membrilla-Fernandez E., Salvans S., Serradilla-Martin M., Pardo P. S., Rivera-Alonso D., Dziakova J., Huguet J. M., Valle N. P., Ruiz E. C., Valcarcel C. R., Moreno C. R., Salazar Y. T. M., Garcia J. J. R., Mico S. S., Lopez J. R., Farre S. P., Gomez M. S., Petit N. M., Titos-Garcia A., Aranda-Narvaez J. M., Romacho-Lopez L., Sanchez-Guillen L., Aranaz-Ostariz V., Bosch-Ramirez M., Martinez-Perez A., Martinez-Lopez E., Sebastian-Tomas J. C., Jimenez-Riera G., Jimenez-Vega J., Cuellar J. A. N., Campos-Serra A., Munoz-Campana A., Gracia-Roman R., Alegre J. M., Pinto F. L., O'Sullivan S. N., Antona F. B., Jimenez B. M., Lopez-Sanchez J., Carmona Z. G., Fernandez R. T., Sierra I. B., de Leon L. R. G., Moreno V. P., Iglesias E., Cumplido P. L., Bravo A. A., Simo I. R., Dominguez C. L., Caamano A. G., Lozano R. C., Martinez M. D., Torres A. N., de Quiros J. T. M. B., Pellino G., Cloquell M. M., Moller E. G., Jalal-Eldin S., Abdoun A. K., Hamid H. K. S., Lohsiriwat V., Mongkhonsupphawan A., Baraket O., Ayed K., Abbassi I., Ali A. B., Ammar H., Kchaou A., Tlili A., Zribi I., Colak E., Polat S., Koylu Z. A., Guner A., Usta M. A., Reis M. E., Mantoglu B., Gonullu E., Akin E., Altintoprak F., Bayhan Z., Firat N., Isik A., Memis U., Bayrak M., Altintas Y., Kara Y., Bozkurt M. A., Kocatas A., Das K., Seker A., Ozer N., Atici S. D., Tuncer K., Kaya T., Ozkan Z., Ilhan O., Agackiran I., Uzunoglu M. Y., Demirbas E., Altinel Y., Meric S., Hacim N. A., Uymaz D. S., Omarov N., Balik E., Tebala G. D., Khalil H., Rana M., Khan M., Florence C., Swaminathan C., Leo C. A., Liasis L., Watfah J., Trostchansky I., Delgado E., Pontillo M., Latifi R., Coimbra R., Edwards S., Lopez A., Velmahos G., Dorken A., Gebran A., Palmer A., Oury J., Bardes J. M., Seng S. S., Coffua L. S., Ratnasekera A., Egodage T., Echeverria-Rosario K., Armento I., Napolitano L. M., Sangji N. F., Hemmila M., Quick J. A., Austin T. R., Hyman T. S., Curtiss W., McClure A., Cairl N., Biffl W. L., Truong H. P., Schaffer K., Reames S., Banchini F., Capelli P., Coccolini F., Sartelli M., Bravi F., Vallicelli C., Agnoletti V., Baiocchi G. L., Catena F., Perrone, G, Giuffrida, M, Abu-Zidan, F, Kruger, V, Livrini, M, Petracca, G, Rossi, G, Tarasconi, A, Tian, B, Bonati, E, Mentz, R, Mazzini, F, Campana, J, Gasser, E, Kafka-Ritsch, R, Felsenreich, D, Dawoud, C, Riss, S, Gomes, C, Gomes, F, Gonzaga, R, Canton, C, Pereira, B, Fraga, G, Zem, L, Cordeiro-Fonseca, V, de Mesquita Tauil, R, Atanasov, B, Belev, N, Kovachev, N, Melendez, L, Dimova, A, Dimov, S, Zelic, Z, Augustin, G, Bogdanic, B, Moric, T, Chouillard, E, Bajul, M, De Simone, B, Panis, Y, Esposito, F, Notarnicola, M, Lauka, L, Fabbri, A, Hentati, H, Fnaiech, I, Aurelien, V, Bougard, M, Roulet, M, Demetrashvili, Z, Pipia, I, Merabishvili, G, Bouliaris, K, Koukoulis, G, Doudakmanis, C, Xenaki, S, Chrysos, E, Kokkinakis, S, Vassiliu, P, Michalopoulos, N, Margaris, I, Kechagias, A, Avgerinos, K, Katunin, J, Lostoridis, E, Nagorni, E, Pujante, A, Mulita, F, Maroulis, I, Vailas, M, Marinis, A, Siannis, I, Bourbouteli, E, Manatakis, D, Tasis, N, Acheimastos, V, Maria, S, Stylianos, K, Kuzeridis, H, Korkolis, D, Fradelos, E, Kavalieratos, G, Petropoulou, T, Polydorou, A, Papacostantinou, I, Triantafyllou, T, Kimpizi, D, Theodorou, D, Toutouzas, K, Chamzin, A, Frountzas, M, Schizas, D, Karavokyros, I, Syllaios, A, Charalabopoulos, A, Boura, M, Baili, E, Ioannidis, O, Loutzidou, L, Anestiadou, E, Tsouknidas, I, Petrakis, G, Polenta, E, Bains, L, Gupta, R, Singh, S, Khanduri, A, Bala, M, Kedar, A, Pisano, M, Podda, M, Pisanu, A, Martines, G, Trigiante, G, Lantone, G, Agrusa, A, Di Buono, G, Buscemi, S, Veroux, M, Gioco, R, Veroux, G, Oragano, L, Zonta, S, Lovisetto, F, Feo, C, Pesce, A, Fabbri, N, Marino, F, Perrone, F, Vincenti, L, Papagni, V, Picciariello, A, Rossi, S, Picardi, B, Del Monte, S, Visconti, D, Osella, G, Petruzzelli, L, Pignata, G, Andreuccetti, J, D'Alessio, R, Buonfantino, M, Guaitoli, E, Spinelli, S, Sampietro, G, Corbellini, C, Lorusso, L, Frontali, A, Pezzoli, I, Bonomi, A, Chierici, A, Cotsoglou, C, Manca, G, Delvecchio, A, Musa, N, Casati, M, Letizia, L, Abate, E, Ercolani, G, D'Acapito, F, Solaini, L, Guercioni, G, Cicconi, S, Sasia, D, Borghi, F, Giraudo, G, Sena, G, Castaldo, P, Cardamone, E, Portale, G, Zuin, M, Spolverato, Y, Esposito, M, Isernia, R, Di Salvo, M, Manunza, R, Esposito, G, Agus, M, Asti, E, Bernardi, D, Tonucci, T, Luppi, D, Casadei, M, Bonilauri, S, Pezzolla, A, Panebianco, A, Laforgia, R, De Luca, M, Zese, M, Parini, D, Jovine, E, De Sario, G, Lombardi, R, Aprea, G, Palomba, G, Capuano, M, Argenio, G, Orio, G, Armellino, M, Troian, M, Guerra, M, Nagliati, C, Biloslavo, A, Germani, P, Aizza, G, Monsellato, I, Chahrour, A, Anania, G, Bombardini, C, Bagolini, F, Sganga, G, Fransvea, P, Bianchi, V, Boati, P, Ferrara, F, Palmieri, F, Cianci, P, Gattulli, D, Restini, E, Cillara, N, Cannavera, A, Nita, G, Sarnari, J, Roscio, F, Clerici, F, Scandroglio, I, Berti, S, Cadeo, A, Filippelli, A, Conti, L, Grassi, C, Cattaneo, G, Pighin, M, Papis, D, Gambino, G, Bertino, V, Schifano, D, Prando, D, Fogato, L, Cavallo, F, Ansaloni, L, Picheo, R, Pontarolo, N, Depalma, N, Spampinato, M, D'Ugo, S, Lepre, L, Capponi, M, Campa, R, Sarro, G, Dinuzzi, V, Olmi, S, Uccelli, M, Ferrari, D, Inama, M, Moretto, G, Fontana, M, Favi, F, Picariello, E, Rampini, A, Barberis, A, Azzinnaro, A, Oliva, A, Totaro, L, Benzoni, I, Ranieri, V, Capolupo, G, Carannante, F, Caricato, M, Ronconi, M, Casiraghi, S, Casole, G, Pantalone, D, Alemanno, G, Scheiterle, M, Ceresoli, M, Cereda, M, Fumagalli, C, Zanzi, F, Bolzon, S, Guerra, E, Lecchi, F, Cellerino, P, Ardito, A, Scaramuzzo, R, Balla, A, Lepiane, P, Tartaglia, N, Ambrosi, A, Pavone, G, Palini, G, Veneroni, S, Garulli, G, Ricci, C, Torre, B, Russo, I, Rottoli, M, Tanzanu, M, Belvedere, A, Milone, M, Manigrasso, M, De Palma, G, Piccoli, M, Pattacini, G, Magnone, S, Bertoli, P, Massucco, P, Palisi, M, Luzzi, A, Fleres, F, Clarizia, G, Spolini, A, Kobe, Y, Toma, T, Shimamura, F, Parker, R, Ranketi, S, Mitei, M, Svagzdys, S, Pauzas, H, Zilinskas, J, Poskus, T, Kryzauskas, M, Jakubauskas, M, Zakaria, A, Zakaria, Z, Wong, M, Jusoh, A, Zakaria, M, Cruz, D, Elizalde, A, Reynaud, A, Hernandez, E, Monroy, J, Hinojosa-Ugarte, D, Quiodettis, M, Du Bois, M, Latorraca, J, Major, P, Pedziwiatr, M, Pisarska-Adamczyk, M, Waledziak, M, Kwiatkowski, A, Czyzykowski, L, da Costa, S, Ferreira, A, Almeida, F, Rocha, R, Carneiro, C, Perez, D, Carvas, J, Rocha, C, Ferreira, C, Marques, R, Fernandes, U, Leao, P, Goulart, A, Pereira, R, Patrocinio, S, de Mendonca, N, Manso, M, Morais, H, Cardoso, P, Calu, V, Miron, A, Toma, E, Gachabayov, M, Abdullaev, A, Litvin, A, Nechay, T, Tyagunov, A, Yuldashev, A, Bradley, A, Wilson, M, Panyko, A, Lateckova, Z, Lacko, V, Lesko, D, Soltes, M, Radonak, J, Turrado-Rodriguez, V, Termes-Serra, R, Morales-Sevillano, X, Lapolla, P, Mingoli, A, Brachini, G, Degiuli, M, Sofia, S, Reddavid, R, de Manzoni Garberini, A, Buffone, A, del Pozo, E, Aparicio-Sanchez, D, Dos Barbeito, S, Estaire-Gomez, M, Viton-Herrero, R, de los Angeles Gil Olarte-Marquez, M, Gil-Martinez, J, Alconchel, F, Nicolas-Lopez, T, Rahy-Martin, A, Pelloni, M, Banolas-Suarez, R, Mendoza-Moreno, F, Nisa, F, Diez-Alonso, M, Rodas, M, Agundez, M, Andres, M, Moreira, C, Perez, A, Ponce, I, Gonzalez-Castillo, A, Membrilla-Fernandez, E, Salvans, S, Serradilla-Martin, M, Pardo, P, Rivera-Alonso, D, Dziakova, J, Huguet, J, Valle, N, Ruiz, E, Valcarcel, C, Moreno, C, Salazar, Y, Garcia, J, Mico, S, Lopez, J, Farre, S, Gomez, M, Petit, N, Titos-Garcia, A, Aranda-Narvaez, J, Romacho-Lopez, L, Sanchez-Guillen, L, Aranaz-Ostariz, V, Bosch-Ramirez, M, Martinez-Perez, A, Martinez-Lopez, E, Sebastian-Tomas, J, Jimenez-Riera, G, Jimenez-Vega, J, Cuellar, J, Campos-Serra, A, Munoz-Campana, A, Gracia-Roman, R, Alegre, J, Pinto, F, O'Sullivan, S, Antona, F, Jimenez, B, Lopez-Sanchez, J, Carmona, Z, Fernandez, R, Sierra, I, de Leon, L, Moreno, V, Iglesias, E, Cumplido, P, Bravo, A, Simo, I, Dominguez, C, Caamano, A, Lozano, R, Martinez, M, Torres, A, de Quiros, J, Pellino, G, Cloquell, M, Moller, E, Jalal-Eldin, S, Abdoun, A, Hamid, H, Lohsiriwat, V, Mongkhonsupphawan, A, Baraket, O, Ayed, K, Abbassi, I, Ali, A, Ammar, H, Kchaou, A, Tlili, A, Zribi, I, Colak, E, Polat, S, Koylu, Z, Guner, A, Usta, M, Reis, M, Mantoglu, B, Gonullu, E, Akin, E, Altintoprak, F, Bayhan, Z, Firat, N, Isik, A, Memis, U, Bayrak, M, Altintas, Y, Kara, Y, Bozkurt, M, Kocatas, A, Das, K, Seker, A, Ozer, N, Atici, S, Tuncer, K, Kaya, T, Ozkan, Z, Ilhan, O, Agackiran, I, Uzunoglu, M, Demirbas, E, Altinel, Y, Meric, S, Hacim, N, Uymaz, D, Omarov, N, Balik, E, Tebala, G, Khalil, H, Rana, M, Khan, M, Florence, C, Swaminathan, C, Leo, C, Liasis, L, Watfah, J, Trostchansky, I, Delgado, E, Pontillo, M, Latifi, R, Coimbra, R, Edwards, S, Lopez, A, Velmahos, G, Dorken, A, Gebran, A, Palmer, A, Oury, J, Bardes, J, Seng, S, Coffua, L, Ratnasekera, A, Egodage, T, Echeverria-Rosario, K, Armento, I, Napolitano, L, Sangji, N, Hemmila, M, Quick, J, Austin, T, Hyman, T, Curtiss, W, Mcclure, A, Cairl, N, Biffl, W, Truong, H, Schaffer, K, Reames, S, Banchini, F, Capelli, P, Coccolini, F, Sartelli, M, Bravi, F, Vallicelli, C, Agnoletti, V, Baiocchi, G, Catena, F, Perrone G., Giuffrida M., Abu-Zidan F., Kruger V. F., Livrini M., Petracca G. L., Rossi G., Tarasconi A., Tian B. W. C. A., Bonati E., Mentz R., Mazzini F. N., Campana J. P., Gasser E., Kafka-Ritsch R., Felsenreich D. M., Dawoud C., Riss S., Gomes C. A., Gomes F. C., Gonzaga R. A. T., Canton C. A. B., Pereira B. M., Fraga G. P., Zem L. G., Cordeiro-Fonseca V., de Mesquita Tauil R., Atanasov B., Belev N., Kovachev N., Melendez L. J. J., Dimova A., Dimov S., Zelic Z., Augustin G., Bogdanic B., Moric T., Chouillard E., Bajul M., De Simone B., Panis Y., Esposito F., Notarnicola M., Lauka L., Fabbri A., Hentati H., Fnaiech I., Aurelien V., Bougard M., Roulet M., Demetrashvili Z., Pipia I., Merabishvili G., Bouliaris K., Koukoulis G., Doudakmanis C., Xenaki S., Chrysos E., Kokkinakis S., Vassiliu P., Michalopoulos N., Margaris I., Kechagias A., Avgerinos K., Katunin J., Lostoridis E., Nagorni E. -A., Pujante A., Mulita F., Maroulis I., Vailas M., Marinis A., Siannis I., Bourbouteli E., Manatakis D. K., Tasis N., Acheimastos V., Maria S., Stylianos K., Kuzeridis H., Korkolis D., Fradelos E., Kavalieratos G., Petropoulou T., Polydorou A., Papacostantinou I., Triantafyllou T., Kimpizi D., Theodorou D., Toutouzas K., Chamzin A., Frountzas M., Schizas D., Karavokyros I., Syllaios A., Charalabopoulos A., Boura M., Baili E., Ioannidis O., Loutzidou L., Anestiadou E., Tsouknidas I., Petrakis G., Polenta E., Bains L., Gupta R., Singh S. K., Khanduri A., Bala M., Kedar A., Pisano M., Podda M., Pisanu A., Martines G., Trigiante G., Lantone G., Agrusa A., Di Buono G., Buscemi S., Veroux M., Gioco R., Veroux G., Oragano L., Zonta S., Lovisetto F., Feo C. V., Pesce A., Fabbri N., Marino F., Perrone F., Vincenti L., Papagni V., Picciariello A., Rossi S., Picardi B., Del Monte S. R., Visconti D., Osella G., Petruzzelli L., Pignata G., Andreuccetti J., D'Alessio R., Buonfantino M., Guaitoli E., Spinelli S., Sampietro G. M., Corbellini C., Lorusso L., Frontali A., Pezzoli I., Bonomi A., Chierici A., Cotsoglou C., Manca G., Delvecchio A., Musa N., Casati M., Letizia L., Abate E., Ercolani G., D'Acapito F., Solaini L., Guercioni G., Cicconi S., Sasia D., Borghi F., Giraudo G., Sena G., Castaldo P., Cardamone E., Portale G., Zuin M., Spolverato Y., Esposito M., Isernia R. M., Di Salvo M., Manunza R., Esposito G., Agus M., Asti E. L. G., Bernardi D. T., Tonucci T. P., Luppi D., Casadei M., Bonilauri S., Pezzolla A., Panebianco A., Laforgia R., De Luca M., Zese M., Parini D., Jovine E., De Sario G., Lombardi R., Aprea G., Palomba G., Capuano M., Argenio G., Orio G., Armellino M. F., Troian M., Guerra M., Nagliati C., Biloslavo A., Germani P., Aizza G., Monsellato I., Chahrour A. C., Anania G., Bombardini C., Bagolini F., Sganga G., Fransvea P., Bianchi V., Boati P., Ferrara F., Palmieri F., Cianci P., Gattulli D., Restini E., Cillara N., Cannavera A., Nita G. E., Sarnari J., Roscio F., Clerici F., Scandroglio I., Berti S., Cadeo A., Filippelli A., Conti L., Grassi C., Cattaneo G. M., Pighin M., Papis D., Gambino G., Bertino V., Schifano D., Prando D., Fogato L., Cavallo F., Ansaloni L., Picheo R., Pontarolo N., Depalma N., Spampinato M., D'Ugo S., Lepre L., Capponi M. G., Campa R. D., Sarro G., Dinuzzi V. P., Olmi S., Uccelli M., Ferrari D., Inama M., Moretto G., Fontana M., Favi F., Picariello E., Rampini A., Barberis A., Azzinnaro A., Oliva A., Totaro L., Benzoni I., Ranieri V., Capolupo G. T., Carannante F., Caricato M., Ronconi M., Casiraghi S., Casole G., Pantalone D., Alemanno G., Scheiterle M., Ceresoli M., Cereda M., Fumagalli C., Zanzi F., Bolzon S., Guerra E., Lecchi F., Cellerino P., Ardito A., Scaramuzzo R., Balla A., Lepiane P., Tartaglia N., Ambrosi A., Pavone G., Palini G. M., Veneroni S., Garulli G., Ricci C., Torre B., Russo I. S., Rottoli M., Tanzanu M., Belvedere A., Milone M., Manigrasso M., De Palma G. D., Piccoli M., Pattacini G. C., Magnone S., Bertoli P., Massucco P., Palisi M., Luzzi A. -P., Fleres F., Clarizia G., Spolini A., Kobe Y., Toma T., Shimamura F., Parker R., Ranketi S., Mitei M., Svagzdys S., Pauzas H., Zilinskas J., Poskus T., Kryzauskas M., Jakubauskas M., Zakaria A. D., Zakaria Z., Wong M. P. -K., Jusoh A. C., Zakaria M. N., Cruz D. R., Elizalde A. B. R., Reynaud A. B., Hernandez E. E. L., Monroy J. M. V. P., Hinojosa-Ugarte D., Quiodettis M., Du Bois M. E., Latorraca J., Major P., Pedziwiatr M., Pisarska-Adamczyk M., Waledziak M., Kwiatkowski A., Czyzykowski L., da Costa S. D., Pereira B., Ferreira A. R. O., Almeida F., Rocha R., Carneiro C., Perez D. P., Carvas J., Rocha C., Ferreira C., Marques R., Fernandes U., Leao P., Goulart A., Pereira R. G., Patrocinio S. D. D., de Mendonca N. G. G., Manso M. I. C., Morais H. M. C., Cardoso P. S., Calu V., Miron A., Toma E. A., Gachabayov M., Abdullaev A., Litvin A., Nechay T., Tyagunov A., Yuldashev A., Bradley A., Wilson M., Panyko A., Lateckova Z., Lacko V., Lesko D., Soltes M., Radonak J., Turrado-Rodriguez V., Termes-Serra R., Morales-Sevillano X., Lapolla P., Mingoli A., Brachini G., Degiuli M., Sofia S., Reddavid R., de Manzoni Garberini A., Buffone A., del Pozo E. P., Aparicio-Sanchez D., Dos Barbeito S., Estaire-Gomez M., Viton-Herrero R., de los Angeles Gil Olarte-Marquez M. a., Gil-Martinez J., Alconchel F., Nicolas-Lopez T., Rahy-Martin A. C., Pelloni M., Banolas-Suarez R., Mendoza-Moreno F., Nisa F. G. -M., Diez-Alonso M., Rodas M. E. V., Agundez M. C., Andres M. I. P., Moreira C. C. L., Perez A. L., Ponce I. A., Gonzalez-Castillo A. M., Membrilla-Fernandez E., Salvans S., Serradilla-Martin M., Pardo P. S., Rivera-Alonso D., Dziakova J., Huguet J. M., Valle N. P., Ruiz E. C., Valcarcel C. R., Moreno C. R., Salazar Y. T. M., Garcia J. J. R., Mico S. S., Lopez J. R., Farre S. P., Gomez M. S., Petit N. M., Titos-Garcia A., Aranda-Narvaez J. M., Romacho-Lopez L., Sanchez-Guillen L., Aranaz-Ostariz V., Bosch-Ramirez M., Martinez-Perez A., Martinez-Lopez E., Sebastian-Tomas J. C., Jimenez-Riera G., Jimenez-Vega J., Cuellar J. A. N., Campos-Serra A., Munoz-Campana A., Gracia-Roman R., Alegre J. M., Pinto F. L., O'Sullivan S. N., Antona F. B., Jimenez B. M., Lopez-Sanchez J., Carmona Z. G., Fernandez R. T., Sierra I. B., de Leon L. R. G., Moreno V. P., Iglesias E., Cumplido P. L., Bravo A. A., Simo I. R., Dominguez C. L., Caamano A. G., Lozano R. C., Martinez M. D., Torres A. N., de Quiros J. T. M. B., Pellino G., Cloquell M. M., Moller E. G., Jalal-Eldin S., Abdoun A. K., Hamid H. K. S., Lohsiriwat V., Mongkhonsupphawan A., Baraket O., Ayed K., Abbassi I., Ali A. B., Ammar H., Kchaou A., Tlili A., Zribi I., Colak E., Polat S., Koylu Z. A., Guner A., Usta M. A., Reis M. E., Mantoglu B., Gonullu E., Akin E., Altintoprak F., Bayhan Z., Firat N., Isik A., Memis U., Bayrak M., Altintas Y., Kara Y., Bozkurt M. A., Kocatas A., Das K., Seker A., Ozer N., Atici S. D., Tuncer K., Kaya T., Ozkan Z., Ilhan O., Agackiran I., Uzunoglu M. Y., Demirbas E., Altinel Y., Meric S., Hacim N. A., Uymaz D. S., Omarov N., Balik E., Tebala G. D., Khalil H., Rana M., Khan M., Florence C., Swaminathan C., Leo C. A., Liasis L., Watfah J., Trostchansky I., Delgado E., Pontillo M., Latifi R., Coimbra R., Edwards S., Lopez A., Velmahos G., Dorken A., Gebran A., Palmer A., Oury J., Bardes J. M., Seng S. S., Coffua L. S., Ratnasekera A., Egodage T., Echeverria-Rosario K., Armento I., Napolitano L. M., Sangji N. F., Hemmila M., Quick J. A., Austin T. R., Hyman T. S., Curtiss W., McClure A., Cairl N., Biffl W. L., Truong H. P., Schaffer K., Reames S., Banchini F., Capelli P., Coccolini F., Sartelli M., Bravi F., Vallicelli C., Agnoletti V., Baiocchi G. L., and Catena F.
- Abstract
Background: Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann’s procedure (HP) for the treatment of left-sided colonic emergencies. We aim to evaluate the surgical options globally used to treat patients with acute left-sided colonic emergencies and the factors that leading to the choice of treatment, comparing HP and RPA. Methods: This is a prospective, international, multicenter, observational study registered on ClinicalTrials.gov. A total 1215 patients with left-sided colonic emergencies who required surgery were included from 204 centers during the period of March 1, 2020, to May 31, 2020. with a 1-year follow-up. Results: 564 patients (43.1%) were females. The mean age was 65.9 ± 15.6 years. HP was performed in 697 (57.3%) patients and RPA in 384 (31.6%) cases. Complicated acute diverticulitis was the most common cause of left-sided colonic emergencies (40.2%), followed by colorectal malignancy (36.6%). Severe complications (Clavien-Dindo ≥ 3b) were higher in the HP group (P < 0.001). 30-day mortality was higher in HP patients (13.7%), especially in case of bowel perforation and diffused peritonitis. 1-year follow-up showed no differences on ostomy reversal rate between HP and RPA. (P = 0.127). A backward likelihood logistic regression model showed that RPA was preferred in younger patients, having low ASA score (≤ 3), in case of large bowel obstruction, absence of colonic ischemia, longer time from admission to surgery, operating early at the day working hours, by a surgeon who performed more than 50 colorectal resections. Conclusions: After 100 years since the first Hartmann’s procedure, HP remains the most common treatment for left-sided colorectal emergencies. Treatment’s choice depends on patient characteristics, the time of surgery and the experience of the surgeon. RPA should be considered as the gold standard for surgery, with HP being an exception.
- Published
- 2024
5. The influence of anastomotic techniques on postoperative anastomotic complications: Results of the Oesophago-Gastric Anastomosis Audit
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Kamarajah, S.K., Evans, R.P.T., Nepogodiev, D., Hodson, J., Bundred, J.R., Gockel, I., Gossage, J.A., Isik, A., Kidane, B., Mahendran, H.A., Negoi, I., Okonta, K.E., Sayyed, R., van Hillegersberg, R., Vohra, R.S., Wijnhoven, B.P.L., Singh, P., Griffiths, E.A., Alderson, D., Bundred, J., Gossage, J., Jefferies, B., McKay, S., Mohamed, I., Siaw-Acheampong, K., Vohra, R., Wanigasooriya, K., Whitehouse, T., Gjata, A., Moreno, J.I., Takeda, F.R., Guevara Castro, R., Harustiak, T., Bekele, A., Kechagias, A., Kennedy, A., Da Roit, A., Bagajevas, A., Azagra, J.S., Mejía-Fernández, L., El Kafsi, J., Sayyed, R.H., Sousa, M., Sampaio, A.S., Blanco, R., Wallner, B., Schneider, P.M., Hsu, P.K., Gananadha, S., Wills, V., Devadas, M., Duong, C., Talbot, M., Hii, M.W., Jacobs, R., Andreollo, N.A., Johnston, B., Darling, G., Isaza-Restrepo, A., Rosero, G., Arias-Amézquita, F., Raptis, D., Gaedcke, J., Reim, D., Izbicki, J., Egberts, J.H., Dikinis, S., Kjaer, D.W., Larsen, M.H., Achiam, M.P., Saarnio, J., Theodorou, D., Liakakos, T., Korkolis, D.P., Robb, W.B., Collins, C., Murphy, T., Reynolds, J., Tonini, V., Migliore, M., Bonavina, L., Valmasoni, M., Bardini, R., Weindelmayer, J., Terashima, M., White, R.E., Alghunaim, E., Elhadi, M., Leon-Takahashi, A.M., Medina-Franco, H., Lau, P.C., Heisterkamp, J., Rosman, C., Beban, G., Babor, R., Gordon, A., Rossaak, J.I., Pal, K.M.I., Qureshi, A.U., Naqi, S.A., Syed, A.A., Barbosa, J., Vicente, C.S., Leite, J., Freire, J., Casaca, R., Costa, R.C.T., Scurtu, R.R., Mogoanta, S.S., Bolca, C., Constantinoiu, S., Sekhniaidze, D., Bjelović, M., So, J.B.Y., Gačevski, G., Loureiro, C., Pera, M., Bianchi, A., Moreno Gijón, M., Martín Fernández, J., Trugeda Carrera, M.S., Vallve-Bernal, M., Cítores Pascual, M.A., Elmahi, S., Halldestam, I., Hedberg, J., Mönig, S., Gutknecht, S., Tez, M., Guner, A., Tirnaksiz, M.B., Colak, E., Sevinç, B., Hindmarsh, A., Khan, I., Khoo, D., Byrom, R., Gokhale, J., Wilkerson, P., Jain, P., Chan, D., Robertson, K., Iftikhar, S., Skipworth, R., Forshaw, M., Higgs, S., Nijjar, R., Viswanath, Y.K.S., Turner, P., Dexter, S., Boddy, A., Allum, W.H., Oglesby, S., Cheong, E., Beardsmore, D., Maynard, N., Berrisford, R., Mercer, S., Puig, S., Melhado, R., Kelty, C., Underwood, T., Dawas, K., Lewis, W., Al-Bahrani, A., Bryce, G., Thomas, M., Arndt, A.T., Palazzo, F., Meguid, R.A., Fergusson, J., Beenen, E., Mosse, C., Salim, J., Cheah, S., Wright, T., Cerdeira, M.P., McQuillan, P., Richardson, M., Liem, H., Spillane, J., Yacob, M., Albadawi, F., Thorpe, T., Dingle, A., Cabalag, C., Loi, K., Fisher, O.M., Ward, S., Read, M., Johnson, M., Bassari, R., Bui, H., Cecconello, I., Sallum, R.A.A., da Rocha, J.R.M., Lopes, L.R., Tercioti, V., Jr, Coelho, J.D.S., Ferrer, J.A.P., Buduhan, G., Tan, L., Srinathan, S., Shea, P., Yeung, J., Allison, F., Carroll, P., Vargas-Barato, F., Gonzalez, F., Ortega, J., Nino-Torres, L., Beltrán-García, T.C., Castilla, L., Pineda, M., Bastidas, A., Gómez-Mayorga, J., Cortés, N., Cetares, C., Caceres, S., Duarte, S., Pazdro, A., Snajdauf, M., Faltova, H., Sevcikova, M., Mortensen, P.B., Katballe, N., Ingemann, T., Morten, B., Kruhlikava, I., Ainswort, A.P., Stilling, N.M., Eckardt, J., Holm, J., Thorsteinsson, M., Siemsen, M., Brandt, B., Nega, B., Teferra, E., Tizazu, A., Kauppila, J.H., Koivukangas, V., Meriläinen, S., Gruetzmann, R., Krautz, C., Weber, G., Golcher, H., Emons, G., Azizian, A., Ebeling, M., Niebisch, S., Kreuser, N., Albanese, G., Hesse, J., Volovnik, L., Boecher, U., Reeh, M., Triantafyllou, S., Schizas, D., Michalinos, A., Balli, E., Mpoura, M., Charalabopoulos, A., Manatakis, D.K., Balalis, D., Bolger, J., Baban, C., Mastrosimone, A., McAnena, O., Quinn, A., Ó Súilleabháin, C.B., Hennessy, M.M., Ivanovski, I., Khizer, H., Ravi, N., Donlon, N., Cervellera, M., Vaccari, S., Bianchini, S., Sartarelli, l., Asti, E., Bernardi, D., Merigliano, S., Provenzano, L., Scarpa, M., Saadeh, L., Salmaso, B., De Manzoni, G., Giacopuzzi, S., La Mendola, R., De Pasqual, C.A., Tsubosa, Y., Niihara, M., Irino, T., Makuuchi, R., Ishii, K., Mwachiro, M., Fekadu, A., Odera, A., Mwachiro, E., AlShehab, D., Ahmed, H.A., Shebani, A.O., Elhadi, A., Elnagar, F.A., Elnagar, H.F., Makkai-Popa, S.T., Wong, L.F., Tan, Y.R., Thannimalai, S., Ho, C.A., Pang, W.S., Tan, J.H., Basave, H.N.L., Cortés-González, R., Lagarde, S.M., van Lanschot, J.J.B., Cords, C., Jansen, W.A., Martijnse, I., Matthijsen, R., Bouwense, S., Klarenbeek, B., Verstegen, M., van Workum, F., Ruurda, J.P., van der Sluis, P.C., de Maat, M., Evenett, N., Johnston, P., Patel, R., MacCormick, A., Young, M., Smith, B., Ekwunife, C., Memon, A.H., Shaikh, K., Wajid, A., Khalil, N., Haris, M., Mirza, Z.U., Qudus, S.B.A., Sarwar, M.Z., Shehzadi, A., Raza, A., Jhanzaib, M.H., Farmanali, J., Zakir, Z., Shakeel, O., Nasir, I., Khattak, S., Baig, M., MA, Noor, Ahmed, H.H., Naeem, A., Pinho, A.C., da Silva, R., Bernardes, A., Campos, J.C., Matos, H., Braga, T., Monteiro, C., Ramos, P., Cabral, F., Gomes, M.P., Martins, P.C., Correia, A.M., Videira, J.F., Ciuce, C., Drasovean, R., Apostu, R., Paitici, S., Racu, A.E., Obleaga, C.V., Beuran, M., Stoica, B., Ciubotaru, C., Negoita, V., Cordos, I., Birla, R.D., Predescu, D., Hoara, P.A., Tomsa, R., Shneider, V., Agasiev, M., Ganjara, I., Gunjić, D., Veselinović, M., Babič, T., Chin, T.S., Shabbir, A., Kim, G., Crnjac, A., Samo, H., Díez del Val, I., Leturio, S., Ramón, J.M., Dal Cero, M., Rifá, S., Rico, M., Pagan Pomar, A., Martinez Corcoles, J.A., Rodicio Miravalles, J.L., Pais, S.A., Turienzo, S.A., Alvarez, L.S., Campos, P.V., Rendo, A.G., García, S.S., Santos, E.P.G., Martínez, E.T., Fernández Díaz, M.J., Magadán Álvarez, C., Concepción Martín, V., Díaz López, C., Rosat Rodrigo, A., Pérez Sánchez, L.E., Bailón Cuadrado, M., Tinoco Carrasco, C., Choolani Bhojwani, E., Sánchez, D.P., Ahmed, M.E., Dzhendov, T., Lindberg, F., Rutegård, M., Sundbom, M., Mickael, C., Colucci, N., Schnider, A., Er, S., Kurnaz, E., Turkyilmaz, S., Turkyilmaz, A., Yildirim, R., Baki, B.E., Akkapulu, N., Karahan, O., Damburaci, N., Hardwick, R., Safranek, P., Sujendran, V., Bennett, J., Afzal, Z., Shrotri, M., Chan, B., Exarchou, K., Gilbert, T., Amalesh, T., Mukherjee, D., Mukherjee, S., Wiggins, T.H., Kennedy, R., McCain, S., Harris, A., Dobson, G., Davies, N., Wilson, I., Mayo, D., Bennett, D., Young, R., Manby, P., Blencowe, N., Schiller, M., Byrne, B., Mitton, D., Wong, V., Elshaer, A., Cowen, M., Menon, V., Tan, L.C., McLaughlin, E., Koshy, R., Sharp, C., Brewer, H., Das, N., Cox, M., Al Khyatt, W., Worku, D., Iqbal, R., Walls, L., McGregor, R., Fullarton, G., Macdonald, A., MacKay, C., Craig, C., Dwerryhouse, S., Hornby, S., Jaunoo, S., Wadley, M., Baker, C., Saad, M., Kelly, M., Davies, A., Di Maggio, F., Mistry, P., Singhal, R., Tucker, O., Kapoulas, S., Powell-Brett, S., Davis, P., Bromley, G., Watson, L., Verma, R., Ward, J., Shetty, V., Ball, C., Pursnani, K., Sarela, A., Sue Ling, H., Mehta, S., Hayden, J., To, N., Palser, T., Hunter, D., Supramaniam, K., Butt, Z., Ahmed, A., Kumar, S., Chaudry, A., Moussa, O., Kordzadeh, A., Lorenzi, B., Wilson, M., Patil, P., Noaman, I., Willem, J., Bouras, G., Evans, R., Singh, M., Warrilow, H., Ahmad, A., Tewari, N., Yanni, F., Couch, J., Theophilidou, E., Reilly, J.J., van Boxel Gijs, Akbari, K., Zanotti, D., Sgromo, B., Sanders, G., Wheatley, T., Ariyarathenam, A., Reece-Smith, A., Humphreys, L., Choh, C., Carter, N., Knight, B., Pucher, P., Athanasiou, A., Tan, B., Abdulrahman, M., Vickers, J., Akhtar, K., Chaparala, R., Brown, R., Alasmar, M.M.A., Ackroyd, R., Patel, K., Tamhankar, A., Wyman, A., Walker, R., Grace, B., Abbassi, N., Slim, N., Ioannidi, L., Blackshaw, G., Havard, T., Escofet, X., Powell, A., Owera, A., Rashid, F., Jambulingam, P., Padickakudi, J., Ben-Younes, H., Mccormack, K., Makey, I.A., Karush, M.K., Seder, C.W., Liptay, M.J., Chmielewski, G., Rosato, E.L., Berger, A.C., Zheng, R., Okolo, E., Singh, A., Scott, C.D., Weyant, M.J., and Mitchell, J.D.
- Published
- 2022
- Full Text
- View/download PDF
6. Postoperative and Pathological Outcomes of CROSS and FLOT as Neoadjuvant Therapy for Esophageal and Junctional Adenocarcinoma: An International Cohort Study From the Oesophagogastric Anastomosis Audit (OGAA)
- Author
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Steering Committee, Alderson, D, Bundred, J, RPT, Evans, Gossage, J, Griffiths, EA, Jefferies, B, Kamarajah, SK, McKay, S, Mohamed, I, Nepogodiev, D, Siaw- Acheampong, K, Singh, P, van Hillegersberg, R, Vohra, R, Wanigasooriya, K, Whitehouse, T., National Leads, Gjata, A, Moreno, JI, Takeda, FR, Kidane, B, Guevara Castro, R, Harustiak, T, Bekele, A, Kechagias, A, Gockel, I, Kennedy, A, Da Roit, A, Bagajevas, A, Azagra, JS, Mahendran, HA, Mejía-Fernández, L, Wijnhoven, BPL, El Kafsi, J, Sayyed, RH, Sousa, M, Sampaio, AS, Negoi, I, Blanco, R, Wallner, B, Schneider, PM, Hsu, PK, Isik, A, Site Leads, Gananadha, S, Wills, V, Devadas, M, Duong, C, Talbot, M, Hii, MW, Jacobs, R, Andreollo, NA, Johnston, B, Darling, G, Isaza-Restrepo, A, Rosero, G, Arias- Amézquita, F, Raptis, D, Gaedcke, J, Reim, D, Izbicki, J, Egberts, JH, Dikinis, S, Kjaer, DW, Larsen, MH, Achiam, MP, Saarnio, J, Theodorou, D, Liakakos, T, Korkolis, DP, Robb, WB, Collins, C, Murphy, T, Reynolds, J, Tonini, V, Migliore, M, Bonavina, L, Valmasoni, M, Bardini, R, Weindelmayer, J, Terashima, M, White, RE, Alghunaim, E, Elhadi, M, Leon-Takahashi, AM, Medina-Franco, H, Lau, PC, Okonta, KE, Heisterkamp, J, Rosman, C, van Hillegersberg, R, Beban, G, Babor, R, Gordon, A, Rossaak, JI, Pal, KMI, Qureshi, AU, Naqi, SA, Syed, AA, Barbosa, J, Vicente, CS, Leite, J, Freire, J, Casaca, R, Costa, RCT, Scurtu, RR, Mogoanta, SS, Bolca, C, Constantinoiu, S, Sekhniaidze, D, Bjelović, M, So, JBY, Gačevski, G, Loureiro, C, Pera, M, Bianchi, A, Moreno Gijón, M, Martín Fernández, J, Trugeda Carrera, MS, Vallve-Bernal, M, Cítores Pascual, MA, Elmahi, S, Halldestam, I, Hedberg, J, Mönig, S, Gutknecht, S, Tez, M, Guner, A, Tirnaksiz, MB, Colak, E, Sevinç, B, Hindmarsh, A, Khan, I, Khoo, D, Byrom, R, Gokhale, J, Wilkerson, P, Jain, P, Chan, D, Robertson, K, Iftikhar, S, Skipworth, R, Forshaw, M, Higgs, S, Gossage, J, Nijjar, R, Viswanath, YKS, Turner, P, Dexter, S, Boddy, A, Allum, WH, Oglesby, S, Cheong, E, Beardsmore, D, Vohra, R, Maynard, N, Berrisford, R, Mercer, S, Puig, S, Melhado, R, Kelty, C, Underwood, T, Dawas, K, Lewis, W, Al-Bahrani, A, Bryce, G, Thomas, M, Arndt, AT, Palazzo, F, Meguid, RA, Collaborators, Fergusson, J, Beenen, E, Mosse, C, Salim, J, Cheah, S, Wright, T, Cerdeira, MP, McQuillan, P, Richardson, M, Liem, H, Spillane, J, Yacob, M, Albadawi, F, Thorpe, T, Dingle, A, Cabalag, C, Loi, K, Fisher, OM, Ward, S, Read, M, Johnson, M, Bassari, R, Bui, H, Cecconello, I, RAA, Sallum, da Rocha, JRM, Lopes, LR, Tercioti, V, Jr, JDS, Coelho, Ferrer, JAP, Buduhan, G, Tan, L, Srinathan, S, Shea, P, Yeung, J, Allison, F, Carroll, P, Vargas-Barato, F, Gonzalez, F, Ortega, J, Nino-Torres, L, Beltrán-García, TC, Castilla, L, Pineda, M, Bastidas, A, Gómez-Mayorga, J, Cortés, N, Cetares, C, Caceres, S, Duarte, S, Pazdro, A, Snajdauf, M, Faltova, H, Sevcikova, M, Mortensen, PB, Katballe, N, Ingemann, T, Kruhlikava, Morten B, I, Ainswort, AP, Stilling, NM, Eckardt, J, Holm, J, Thorsteinsson, M, Siemsen, M, Brandt, B, Nega, B, Teferra, E, Tizazu, A, Kauppila, JH, Koivukangas, V, Meriläinen, S, Gruetzmann, R, Krautz, C, Weber, G, Golcher, H, Emons, G, Azizian, A, Ebeling, M, Niebisch, S, Kreuser, N, Albanese, G, Hesse, J, Volovnik, L, Boecher, U, Reeh, M, Triantafyllou, S, Schizas, D, Michalinos, A, Balli, E, Mpoura, M, Charalabopoulos, A, Manatakis, DK, Balalis, D, Bolger, J, Baban, C, Mastrosimone, A, McAnena, O, Quinn, A, Ó Súilleabháin, CB, Hennessy, MM, Ivanovski, I, Khizer, H, Ravi, N, Donlon, N, Cervellera, M, Vaccari, S, Bianchini, S, Sartarelli, l, Asti, E, Bernardi, D, Merigliano, S, Provenzano, L, Scarpa, M, Saadeh, L, Salmaso, B, De Manzoni, G, Giacopuzzi, S, La Mendola, R, De Pasqual, CA, Tsubosa, Y, Niihara, M, Irino, T, Makuuchi, R, Ishii, K, Mwachiro, M, Fekadu, A, Odera, A, Mwachiro, E, AlShehab, D, Ahmed, HA, Shebani, AO, Elhadi, A, Elnagar, FA, Elnagar, HF, Makkai-Popa, ST, Wong, LF, Tan, YR, Thannimalai, S, Ho, CA, Pang, WS, Tan, JH, HNL, Basave, Cortés-González, R, Lagarde, SM, van Lanschot, JJB, Cords, C, Jansen, WA, Martijnse, I, Matthijsen, R, Bouwense, S, Klarenbeek, B, Verstegen, M, van Workum, F, Ruurda, JP, van der Sluis, PC, de Maat, M, Evenett, N, Johnston, P, Patel, R, MacCormick, A, Young, M, Smith, B, Ekwunife, C, Memon, AH, Shaikh, K, Wajid, A, Khalil, N, Haris, M, Mirza, ZU, SBA, Qudus, Sarwar, MZ, Shehzadi, A, Raza, A, Jhanzaib, MH, Farmanali, J, Zakir, Z, Shakeel, O, Nasir, I, Khattak, S, Baig, M, Noor, MA, Ahmed, HH, Naeem, A, Pinho, AC, da Silva, R, Bernardes, A, Campos, JC, Matos, H, Braga, T, Monteiro, C, Ramos, P, Cabral, F, Gomes, MP, Martins, PC, Correia, AM, Videira, JF, Ciuce, C, Drasovean, R, Apostu, R, Ciuce, C, Paitici, S, Racu, AE, Obleaga, CV, Beuran, M, Stoica, B, Negoita, Ciubotaru C, V, Cordos, I, Birla, RD, Predescu, D, Hoara, PA, Tomsa, R, Shneider, V, Agasiev, M, Ganjara, I, Gunjić, D, Veselinović, M, Babič, T, Chin, TS, Shabbir, A, Kim, G, Crnjac, A, Samo, H, Díez del Val, I, Leturio, S, Ramón, JM, Dal Cero, M, Rifá, S, Rico, M, Pagan Pomar, A, Martinez Corcoles, JA, Rodicio Miravalles, JL, Pais, SA, Turienzo, SA, Alvarez, LS, Campos, PV, Rendo, AG, García, SS, EPG, Santos, Martínez, ET, Fernández Díaz, MJ, Magadán Álvarez, C, Concepción Martín, V, Díaz López, C, Rosat Rodrigo, A, Pérez Sánchez, LE, Bailón Cuadrado, M, Tinoco Carrasco, C, Choolani Bhojwani, E, Sánchez, DP, Ahmed, ME, Dzhendov, T, Lindberg, F, Rutegård, M, Sundbom, M, Mickael, C, Colucci, N, Schnider, A, Er, S, Kurnaz, E, Turkyilmaz, S, Turkyilmaz, A, Yildirim, R, Baki, BE, Akkapulu, N, Karahan, O, Damburaci, N, Hardwick, R, Safranek, P, Sujendran, V, Bennett, J, Afzal, Z, Shrotri, M, Chan, B, Exarchou, K, Gilbert, T, Amalesh, T, Mukherjee, D, Mukherjee, S, Wiggins, TH, Kennedy, R, McCain, S, Harris, A, Dobson, G, Davies, N, Wilson, I, Mayo, D, Bennett, D, Young, R, Manby, P, Blencowe, N, Schiller, M, Byrne, B, Mitton, D, Wong, V, Elshaer, A, Cowen, M, Menon, V, Tan, LC, McLaughlin, E, Koshy, R, Sharp, C, Brewer, H, Das, N, Cox, M, Al Khyatt, W, Worku, D, Iqbal, R, Walls, L, McGregor, R, Fullarton, G, Macdonald, A, MacKay, C, Craig, C, Dwerryhouse, S, Hornby, S, Jaunoo, S, Wadley, M, Baker, C, Saad, M, Kelly, M, Davies, A, Di Maggio, F, McKay, S, Mistry, P, Singhal, R, Tucker, O, Kapoulas, S, Powell-Brett, S, Davis, P, Bromley, G, Watson, L, Verma, R, Ward, J, Shetty, V, Ball, C, Pursnani, K, Sarela, A, Sue Ling, H, Mehta, S, Hayden, J, To, N, Palser, T, Hunter, D, Supramaniam, K, Butt, Z, Ahmed, A, Kumar, S, Chaudry, A, Moussa, O, Kordzadeh, A, Lorenzi B Wilson, M, Patil, P, Noaman, I, Willem, J, Bouras, G, Evans, R, Singh, M, Warrilow, H, Ahmad, A, Tewari, N, Yanni, F, Couch, J, Theophilidou, E, Reilly, JJ, Singh, P, van Boxel, Gijs, Akbari, K, Zanotti, D, Sgromo, B, Sanders, G, Wheatley, T, Ariyarathenam, A, Reece-Smith, A, Humphreys, L, Choh, C, Carter, N, Knight, B, Pucher, P, Athanasiou, A, Mohamed, I, Tan, B, Abdulrahman, M, Vickers, J, Akhtar, K, Chaparala, R, Brown, R, Alasmar, MMA, Ackroyd, R, Patel, K, Tamhankar, A, Wyman, A, Walker, R, Grace, B, Abbassi, N, Slim, N, Ioannidi, L, Blackshaw, G, Havard, T, Escofet, X, Powell, A, Owera, A, Rashid, F, Jambulingam, P, Padickakudi, J, Ben-Younes, H, Mccormack, K, Makey, IA, Karush, MK, Seder, CW, Liptay, MJ, Chmielewski, G, Rosato, EL, Berger, AC, Zheng, R, Okolo, E, Singh, A, Scott, CD, Weyant, MJ, and Mitchell, JD.
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- 2023
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7. ABDOMINAL WALL PSEUDOHERNIA
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Chamzin, A, primary, Theodoropoulos, C, additional, Galyfos, G, additional, Triantafyllou, A, additional, Saliaris, K, additional, Michalopoulos, N V, additional, Toutouzas, K G, additional, and Theodorou, D, additional
- Published
- 2024
- Full Text
- View/download PDF
8. MANAGEMENT OF ACUTE PRESENTATION OF LEFT PARADUODENAL HERNIA WITH SPONTANEOUS REDUCTION
- Author
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Chamzin, A, primary, Theodoropoulos, C, additional, Galyfos, G, additional, Triantafyllou, A, additional, Ioannou, T, additional, Michalopoulos, N V, additional, Toutouzas, K G, additional, and Theodorou, D, additional
- Published
- 2024
- Full Text
- View/download PDF
9. LAPAROSCOPIC TAPP REPAIR OF SPIGELIAN AND BILATERAL INGUINAL HERNIA
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Chamzin, A, primary, Theodoropoulos, C, additional, Galyfos, G, additional, Triantafyllou, A, additional, Michalopoulos, N V, additional, Toutouzas, K G, additional, and Theodorou, D, additional
- Published
- 2024
- Full Text
- View/download PDF
10. TRANSABDOMINAL SUTURING OF INTERNAL INGUINAL ORIFICE DURING LAPAROSCOPIC TAPP REPAIR OF L3 HERNIAS: 6-MONTH FOLLOW-UP OF 15 PATIENTS
- Author
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Chamzin, A, primary, Theodoropoulos, C, additional, Ioannou, T, additional, Triantafyllou, A, additional, Galyfos, G, additional, Michalopoulos, N V, additional, Toutouzas, K G, additional, and Theodorou, D, additional
- Published
- 2024
- Full Text
- View/download PDF
11. Endoscopic Treatment of Anastomotic Leak after Esophagectomy and Gastrectomy
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Katsila, S., additional, Triantafyllou, A., additional, Kakounis, K., additional, Triantafyllou, S., additional, Dimopoulou, K., additional, Theodorou, D., additional, and Xiromeritou, V., additional
- Published
- 2024
- Full Text
- View/download PDF
12. Mortality from esophagectomy for esophageal cancer across low, middle, and high-income countries: An international cohort study
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Kamarajah, S.K., Nepogodiev, D., Bekele, A., Cecconello, I., Evans, R.P.T., Guner, A., Gossage, J.A., Harustiak, T., Hodson, J., Isik, A., Kidane, B., Leon-Takahashi, A.M., Mahendran, H.A., Negoi, I., Okonta, K.E., Rosero, G., Sayyed, R.H., Singh, P., Takeda, F.R., van Hillegersberg, R., Vohra, R.S., White, R.E., Griffiths, E.A., Alderson, D., Bundred, J., Gossage, J., Jefferies, B., McKay, S., Mohamed, I., Siaw- Acheampong, K., Vohra, R., Wanigasooriya, K., Whitehouse, T., Gjata, A., Moreno, J.I., Guevara, Castro R., Kechagias, A., Gockel, I., Kennedy, A., Da Roit, A., Bagajevas, A., Azagra, J.S., Mejía-Fernández, L., Wijnhoven, B.P.L., El Kafsi, J., Sousa, M., Sampaio, A.S., Blanco, R., Wallner, B., Schneider, P.M., Hsu, P.K., Gananadha, S., Wills, V., Devadas, M., Duong, C., Talbot, M., Hii, M.W., Jacobs, R., Andreollo, N.A., Johnston, B., Darling, G., Isaza-Restrepo, A., Arias- Amézquita, F., Raptis, D., Gaedcke, J., Reim, D., Izbicki, J., Egberts, J.H., Dikinis, S., Kjaer, D.W., Larsen, M.H., Achiam, M.P., Saarnio, J., Theodorou, D., Liakakos, T., Korkolis, D.P., Robb, W.B., Collins, C., Murphy, T., Reynolds, J., Tonini, V., Migliore, M., Bonavina, L., Valmasoni, M., Bardini, R., Weindelmayer, J., Terashima, M., Alghunaim, E., Elhadi, M., Medina-Franco, H., Lau, P.C., Heisterkamp, J., Rosman, C., Beban, G., Babor, R., Gordon, A., Rossaak, J.I., Pal, K.M.I., Qureshi, A.U., Naqi, S.A., Syed, A.A., Barbosa, J., Vicente, C.S., Leite, J., Freire, J., Casaca, R., Costa, R.C.T., Scurtu, R.R., Mogoanta, S.S., Bolca, C., Constantinoiu, S., Sekhniaidze, D., Bjelović, M., So, J.B.Y., Gačevski, G., Loureiro, C., Pera, M., Bianchi, A., Moreno, Gijón M., Martín Fernández, J., Trugeda Carrera, M.S., Vallve-Bernal, M., Cítores Pascual, M.A., Elmahi, S., Halldestam, I., Hedberg, J., Mönig, S., Gutknecht, S., Tez, M., Tirnaksiz, M.B., Colak, E., Sevinç, B., Hindmarsh, A., Khan, I., Khoo, D., Byrom, R., Gokhale, J., Wilkerson, P., Jain, P., Chan, D., Robertson, K., Iftikhar, S., Skipworth, R., Forshaw, M., Higgs, S., Nijjar, R., Viswanath, Y.K.S., Turner, P., Dexter, S., Boddy, A., Allum, W.H., Oglesby, S., Cheong, E., Beardsmore, D., Maynard, N., Berrisford, R., Mercer, S., Puig, S., Melhado, R., Kelty, C., Underwood, T., Dawas, K., Lewis, W., Al-Bahrani, A., Bryce, G., Thomas, M., Arndt, A.T., Palazzo, F., Meguid, R.A., Fergusson, J., Beenen, E., Mosse, C., Salim, J., Cheah, S., Wright, T., Cerdeira, M.P., McQuillan, P., Richardson, M., Liem, H., Spillane, J., Yacob, M., Albadawi, F., Thorpe, T., Dingle, A., Cabalag, C., Loi, K., Fisher, O.M., Ward, S., Read, M., Johnson, M., Bassari, R., Bui, H., Sallum, R.A.A., da Rocha, J.R.M., Lopes, L.R., Tercioti, V., Jr., Coelho, J.D., Ferrer, J.A.P., Buduhan, G., Tan, L., Srinathan, S., Shea, P., Yeung, J., Allison, F., Carroll, P., Vargas-Barato, F., Gonzalez, F., Ortega, J., Nino-Torres, L., Beltrán-García, T.C., Castilla, L., Pineda, M., Bastidas, A., Gómez-Mayorga, J., Cortés, N., Cetares, C., Caceres, S., Duarte, S., Pazdro, A., Snajdauf, M., Faltova, H., Sevcikova, M., Mortensen, P.B., Katballe, N., Ingemann, T., Morten, B., Kruhlikava, I., Ainswort, A.P., Stilling, N.M., Eckardt, J., Holm, J., Thorsteinsson, M., Siemsen, M., Brandt, B., Nega, B., Teferra, E., Tizazu, A., Kauppila, J.H., Koivukangas, V., Meriläinen, S., Gruetzmann, R., Krautz, C., Weber, G., Golcher, H., Emons, G., Azizian, A., Ebeling, M., Niebisch, S., Kreuser, N., Albanese, G., Hesse, J., Volovnik, L., Boecher, U., Reeh, M., Triantafyllou, S., Schizas, D., Michalinos, A., Mpali, E., Mpoura, M., Charalabopoulos, A., Manatakis, D.K., Balalis, D., Bolger, J., Baban, C., Mastrosimone, A., McAnena, O., Quinn, A., Ó Súilleabháin, C.B., Hennessy, M.M., Ivanovski, I., Khizer, H., Ravi, N., Donlon, N., Cervellera, M., Vaccari, S., Bianchini, S., Sartarelli, l, Asti, E., Bernardi, D., Merigliano, S., Provenzano, L., Scarpa, M., Saadeh, L., Salmaso, B., De Manzoni, G., Giacopuzzi, S., La Mendola, R., De Pasqual, C.A., Tsubosa, Y., Niihara, M., Irino, T., Makuuchi, R., Ishii, K., Mwachiro, M., Fekadu, A., Odera, A., Mwachiro, E., AlShehab, D., Ahmed, H.A., Shebani, A.O., Elhadi, A., Elnagar, F.A., Elnagar, H.F., Makkai-Popa, S.T., Wong, L.F., Tan, Y.R., Thannimalai, S., Ho, C.A., Pang, W.S., Tan, J.H., Basave, H.N.L., Cortés-González, R., Lagarde, S.M., van Lanschot, J.J.B., Cords, C., Jansen, W.A., Martijnse, I., Matthijsen, R., Bouwense, S., Klarenbeek, B., Verstegen, M., van Workum, F., Ruurda, J.P., van der Sluis, P.C., de Maat, M., Evenett, N., Johnston, P., Patel, R., MacCormick, A., Young, M., Smith, B., Ekwunife, C., Memon, A.H., Shaikh, K., Wajid, A., Khalil, N., Haris, M., Mirza, Z.U., Qudus, S.B.A., Sarwar, M.Z., Shehzadi, A., Raza, A., Jhanzaib, M.H., Farmanali, J., Zakir, Z., Shakeel, O., Nasir, I., Khattak, S., Baig, M., Noor, M.A., Ahmed, H.H., Naeem, A., Pinho, A.C., da Silva, R., Bernardes, A., Campos, J.C., Matos, H., Braga, T., Monteiro, C., Ramos, P., Cabral, F., Gomes, M.P., Martins, P.C., Correia, A.M., Videira, J.F., Ciuce, C., Drasovean, R., Apostu, R., Paitici, S., Racu, A.E., Obleaga, C.V., Beuran, M., Stoica, B., Ciubotaru, C., Negoita, V., Cordos, I., Birla, R.D., Predescu, D., Hoara, P.A., Tomsa, R., Shneider, V., Agasiev, M., Ganjara, I., Gunjić, D., Veselinović, M., Babič, T., Chin, T.S., Shabbir, A., Kim, G., Crnjac, A., Samo, H., Díez del Val, I., Leturio, S., Ramón, J.M., Dal Cero, M., Rifá, S., Rico, M., Pagan Pomar, A., Martinez Corcoles, J.A., Rodicio Miravalles, J.L., Pais, S.A., Turienzo, S.A., Alvarez, L.S., Campos, P.V., Rendo, A.G., García, S.S., Santos, E.P.G., Martínez, E.T., Fernández, Díaz MJ., Magadán, Álvarez C., Concepción, Martín V., Díaz, López C., Rosat, Rodrigo A., Pérez, Sánchez LE., Bailón, Cuadrado M., Tinoco, Carrasco C., Choolani Bhojwani, E., Sánchez, D.P., Ahmed, M.E., Dzhendov, T., Lindberg, F., Rutegård, M., Sundbom, M., Mickael, C., Colucci, N., Schnider, A., Er, S., Kurnaz, E., Turkyilmaz, S., Turkyilmaz, A., Yildirim, R., Baki, B.E., Akkapulu, N., Karahan, O., Damburaci, N., Hardwick, R., Safranek, P., Sujendran, V., Bennett, J., Afzal, Z., Shrotri, M., Chan, B., Exarchou, K., Gilbert, T., Amalesh, T., Mukherjee, D., Mukherjee, S., Wiggins, T.H., Kennedy, R., McCain, S., Harris, A., Dobson, G., Davies, N., Wilson, I., Mayo, D., Bennett, D., Young, R., Manby, P., Blencowe, N., Schiller, M., Byrne, B., Mitton, D., Wong, V., Elshaer, A., Cowen, M., Menon, V., Tan, L.C., McLaughlin, E., Koshy, R., Sharp, C., Brewer, H., Das, N., Cox, M., Al Khyatt, W., Worku, D., Iqbal, R., Walls, L., McGregor, R., Fullarton, G., Macdonald, A., MacKay, C., Craig, C., Dwerryhouse, S., Hornby, S., Jaunoo, S., Wadley, M., Baker, C., Saad, M., Kelly, M., Davies, A., Di Maggio, F., Mistry, P., Singhal, R., Tucker, O., Kapoulas, S., Powell-Brett, S., Davis, P., Bromley, G., Watson, L., Verma, R., Ward, J., Shetty, V., Ball, C., Pursnani, K., Sarela, A., Sue, Ling H., Mehta, S., Hayden, J., To, N., Palser, T., Hunter, D., Supramaniam, K., Butt, Z., Ahmed, A., Kumar, S., Chaudry, A., Moussa, O., Kordzadeh, A., Lorenzi, B., Wilson, M., Patil, P., Noaman, I., Willem, J., Bouras, G., Evans, R., Singh, M., Warrilow, H., Ahmad, A., Tewari, N., Yanni, F., Couch, J., Theophilidou, E., Reilly, J.J., van Boxel, Gijs, Akbari, K., Zanotti, D., Sgromo, B., Sanders, G., Wheatley, T., Ariyarathenam, A., Reece-Smith, A., Humphreys, L., Choh, C., Carter, N., Knight, B., Pucher, P., Athanasiou, A., Tan, B., Abdulrahman, M., Vickers, J., Akhtar, K., Chaparala, R., Brown, R., Alasmar, M.M.A., Ackroyd, R., Patel, K., Tamhankar, A., Wyman, A., Walker, R., Grace, B., Abbassi, N., Slim, N., Ioannidi, L., Blackshaw, G., Havard, T., Escofet, X., Powell, A., Owera, A., Rashid, F., Jambulingam, P., Padickakudi, J., Ben-Younes, H., Mccormack, K., Makey, I.A., Karush, M.K., Seder, C.W., Liptay, M.J., Chmielewski, G., Rosato, E.L., Berger, A.C., Zheng, R., Okolo, E., Singh, A., Scott, C.D., Weyant, M.J., and Mitchell, J.D.
- Published
- 2021
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13. The role of nutritional assessment in predicting postoperative outcomes after upper gastrointestinal cancer surgery: A prospective observational trial
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Schizas, D., primary, Karanikki, E., additional, Frountzas, M., additional, Lidoriki, I., additional, Kyriakidou, M., additional, Moisidis, I., additional, Kozadinos, A., additional, Mylonakis, A., additional, Theodorou, D., additional, and Toutouzas, K.G., additional
- Published
- 2023
- Full Text
- View/download PDF
14. Infected pancreatic necrosis: outcomes and clinical predictors of mortality. A post hoc analysis of the MANCTRA-1 international study
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Podda, M, Pellino, G, Di Saverio, S, Coccolini, F, Pacella, D, Cioffi, S, Virdis, F, Balla, A, Ielpo, B, Pata, F, Poillucci, G, Ortenzi, M, Damaskos, D, De Simone, B, Sartelli, M, Leppaniemi, A, Jayant, K, Catena, F, Giuliani, A, Di Martino, M, Pisanu, A, Gerardi, C, Gourgiotis, S, Riboni, C, Giordano, A, Ferrario, L, Agnoletti, V, Kruger, Y, Mole, D, Agresta, F, Prieto Calvo, M, Wilson, M, Soggiu, F, Hamdan, A, Gomes, C, Fraga, G, Ioannidis, A, Demetrashvili, Z, Sahani, S, Bains, L, Khamees, A, Ababneh, H, Aljaiuossi, O, Pimentel, S, Mohamad, I, Yusoff, A, Zarnescu, N, Calu, V, Litvin, A, Lesko, D, Elmehrath, A, Elshami, M, de Santibanes, M, Gundara, J, Alawadhi, K, Lui, R, Julianov, A, Ralon, S, Garzali, I, Machain, G, Villalabeitia, I, Quispe-Cruz, D, Orantia, A, Waledziak, M, de Sa, T, Ali, S, Kovacevic, B, Noel, C, Abdalah, H, Kchaou, A, Isik, A, Ansaloni, L, Biffl, W, Guerrieri, M, Sartori, A, Abradelo, M, Nigri, G, Di Lorenzo, N, Mingoli, A, Chiarugi, M, Di Menno Stavron, J, Mazza, O, Valenzuela, J, Pachajoa, D, Alvarez, F, Liano, J, Tefay, J, Alshaikh, A, Hasan, L, Couto Gomes, F, Calderan, T, Hirano, E, Dardanov, D, Saroglu, A, Atanasov, B, Belev, N, Kovachev, N, Chan, S, Lok, H, Salcedo, D, Robayo, D, Trivino, M, Manak, J, de Araujo, J, Sethi, A, Awad, A, Elbadawy, M, Farid, A, Hanafy, A, Nafea, A, Sherief, G, Salah Alzhraa, A, Abdelsalam, W, Emile, S, Elfallal, A, Elfeki, H, Elghadban, H, Shoma, A, Shetiwy, M, Elbahnasawy, M, Mohamed, S, Hamed, E, Khalil, U, Chouillard, E, Gumbs, A, Police, A, Mabilia, A, Khutsishvili, K, Tvaladze, A, Ioannidis, O, Anestiadou, E, Loutzidou, L, Konstantinidis, K, Konstantinidou, S, Manatakis, D, Acheimastos, V, Tasis, N, Michalopoulos, N, Kokoropoulos, P, Papadoliopoulou, M, Sotiropoulou, M, Kapiris, S, Metaxas, P, Tsouknidas, I, Kefili, D, Petrakis, G, Synekidou, E, Dakis, K, Alexandridou, E, Papadopoulos, A, Chouliaras, C, Mouzakis, O, Mulita, F, Maroulis, I, Vailas, M, Triantafyllou, T, Theodorou, D, Lostoridis, E, Nagorni, E, Tourountzi, P, Baili, E, Charalabopoulos, A, Liakakos, T, Schizas, D, Kozadinos, A, Syllaios, A, Machairas, N, Kykalos, S, Stamopoulos, P, Delis, S, Farazi-Chongouki, C, Kalaitzakis, E, Giannarakis, M, Lasithiotakis, K, Petra, G, Gupta, A, Medappil, N, Muthukrishnan, V, Kamar, J, Lal, P, Agarwal, R, Magnoli, M, Aonzo, P, Serventi, A, Di Lascio, P, Pinto, M, Bergamini, C, Bottari, A, Fortuna, L, Martellucci, J, Cicako, A, Miglietta, C, Morino, M, Delogu, D, Picchetto, A, Assenza, M, D'Ambrosio, G, Argenio, G, Armellino, M, Ioia, G, Occhionorelli, S, Andreotti, D, Domenico, L, Luppi, D, Casadei, M, Di Donato, L, Manoochehri, F, Marchese, T, Sergi, W, Manca, R, Murgia, R, Piras, E, Conti, L, Gianazza, S, Rizzi, A, Segalini, E, Monti, M, Iiritano, E, Mariani, N, De Nicola, E, Scifo, G, Pignata, G, Andreuccetti, J, Fleres, F, Clarizia, G, Spolini, A, Biloslavo, A, Germani, P, Mastronardi, M, Bogoni, S, Palmisano, S, De Manzini, N, Marino, M, Martines, G, Trigiante, G, Lagouvardou, E, Anania, G, Bombardini, C, Oppici, D, Pilia, T, Murzi, V, Gessa, E, Bracale, U, Di Nuzzo, M, Peltrini, R, Salvetti, F, Vigano, J, Sganga, G, Bianchi, V, Fransvea, P, Fontana, T, Sarro, G, Dinuzzi, V, Scaravilli, L, Papa, M, Jovine, E, Ciabatti, G, Mastrangelo, L, Rottoli, M, Ricci, C, Russo, I, Aiolfi, A, Bona, D, Lombardo, F, Cianci, P, Sederino, M, Bini, R, Chiara, O, Cantafio, S, Coretti, G, Licitra, E, Savino, G, Grimaldi, S, Porfidia, R, Moggia, E, Garino, M, Marafante, C, Pesce, A, Fabbri, N, Feo, C, Marra, E, Troian, M, Drigo, D, Nagliati, C, Muratore, A, Danna, R, Murgese, A, Crespi, M, Guerci, C, Frontali, A, Ferrari, L, Favi, F, Picariello, E, Rampini, A, D'Acapito, F, Ercolani, G, Solaini, L, Palmieri, F, Cali, M, Ferrara, F, Muttillo, I, Muttillo, E, Picardi, B, Galleano, R, Badran, A, Ghazouani, O, Cervellera, M, Campanella, G, Papa, G, Di Bella, A, Perrone, G, Petracca, G, Prioriello, C, Giuffrida, M, Cozzani, F, Rossini, M, Inama, M, Butturini, G, Moretto, G, Morelli, L, Candio, G, Guadagni, S, Cicuttin, E, Cremonini, C, Tartaglia, D, Genovese, V, Cillara, N, Cannavera, A, Deserra, A, Picciariello, A, Papagni, V, Vincenti, L, Bagaglini, G, Sica, G, Lapolla, P, Brachini, G, Bono, D, Nicotera, A, Zago, M, Sammartano, F, Benuzzi, L, Stella, M, Rossi, S, Cerioli, A, Puccioni, C, Olmi, S, Rubicondo, C, Uccelli, M, Guida, A, Lepiane, P, Sasia, D, Giraudo, G, Salomone, S, Belloni, E, Cossa, A, Lancellotti, F, Caronna, R, Chirletti, P, Saullo, P, Troiano, R, Mucilli, F, Barone, M, Ippoliti, M, Grande, M, Sensi, B, Siragusa, L, Santini, A, Di Carlo, I, Veroux, M, Gioco, R, Veroux, G, Curro, G, Ammendola, M, Komaei, I, Navarra, G, Tonini, V, Sartarelli, L, Ceresoli, M, Perrone, S, Roccamatisi, L, Millo, P, Brachet Contul, R, Ponte, E, Zuin, M, Portale, G, Tonello, A, Fratini, G, Bianchini, M, Perotti, B, Doria, E, Lunghi, E, Visconti, D, Al-Shami, K, Awadi, S, Buwaitel, M, Naffa', M, Samhouri, A, Sawalha, H, Ani, M, Fathil, I, Huei, J, Beristain-Hernandez, J, Garcia-Meza, A, Sepulveda-Rdriguez, R, Hernandez, E, Pinzon, C, Condoy, J, Garcia, F, Sadik, M, Kadir, B, Devi, J, Seerani, N, Zainab, Sohail-Asghar, M, Afzal, A, Akbar, A, Lohse, H, Cabrera, Z, Seto, G, Chiuyari, J, Ordemar, J, Rodriguez, M, Orantia-Carlos, A, Quitoy, M, Kwiatkowski, A, Mawlichanow, M, Rocha, M, Soares, C, Stoian, A, Draghici, A, Grigorean, V, Radulescu, R, Costea, R, Zarnescu, E, Kurtenkov, M, Gendrikson, G, Alla-Angelina, V, Arina, T, Kaldarov, A, Gachabayov, M, Abdullaev, A, Milentijevic, M, Karamarkovic, M, Panyko, A, Radonak, J, Soltes, M, Moran, L, Garcia, H, Vega, P, Estevez, S, Ausania, F, Farguell, J, Gonzalez-Abos, C, Sanchez-Cabus, S, Martin, B, Molina, V, Oms, L, Ilzarbe, L, Feijoo, E, Perra, E, Rojas-Bonet, N, Penalba-Palmi, R, Perez-Bru, S, Tur-Martinez, J, Alvarez-Torrado, A, Domingo-Gonzalez, M, Tejedor-Tejada, J, del Alamo, Y, Mendoza-Moreno, F, Garcia-Moreno-Nisa, F, Matias-Garcia, B, Duran, M, Calleja-Lozano, R, de Villar, J, Sanchez-Guillen, L, Caravaca, I, Triguero-Canovas, D, Aparicio, A, Melendez, B, Palacios, A, Landaluce-Olavarria, A, De Francisco, M, Estraviz-Mateos, B, Alconchel, F, Nicolas-Lopez, T, Ramirez, P, Munoz-Cruzado, V, Ciuro, F, del Pozo, E, Pizarro, S, Cabrera, V, Bayo, J, Hamid, H, Roesel, R, Cristaudi, A, Abbas, K, Ali, I, Tlili, A, Bayhan, H, Turkoglu, M, Uzunoglu, M, Azamat, I, Omarov, N, Uymaz, D, Altintoprak, F, Akin, E, First, N, Das, K, Ozer, N, Seker, A, Kara, Y, Bozkurt, M, Kocatas, A, Atici, S, Akalin, M, Calik, B, Colak, E, Altinel, Y, Meric, S, Aktimur, Y, Hudson, V, Duval, J, Khan, M, Saad, A, Kaur, M, Bradley, A, Fox, K, Tomasi, I, Beasley, D, Prasanti, A, Kotecha, P, Ebied, H, Paul, M, Sheth, H, Gerogiannis, I, Gaber, M, Sheikh, Z, Seth, S, Kunitsyna, M, Leo, C, Bellato, V, Zafar, N, Elserafy, A, Bond-smith, G, Tebala, G, Mathur, P, Abid, I, Chidumije, N, Sandhar, P, Ullah, S, Lezama, T, Anwaar, M, Magee, C, Ahmed, S, Davies, B, Apollos, J, Mccormack, K, Choudhary, H, Doulias, T, Morrison, T, Palepa, A, Cal, F, Sanchez, L, Dominguez, F, Al-Raimi, I, Alshargabi, H, Meead, A, Chooklin, S, Chuklin, S, Bilyak, A, Podda M., Pellino G., Di Saverio S., Coccolini F., Pacella D., Cioffi S. P. B., Virdis F., Balla A., Ielpo B., Pata F., Poillucci G., Ortenzi M., Damaskos D., De Simone B., Sartelli M., Leppaniemi A., Jayant K., Catena F., Giuliani A., Di Martino M., Pisanu A., Gerardi C., Gourgiotis S., Riboni C., Giordano A., Ferrario L., Agnoletti V., Kruger Y., Mole D., Agresta F., Prieto Calvo M., Wilson M., Soggiu F., Hamdan A., Gomes C. A., Fraga G., Ioannidis A., Demetrashvili Z., Sahani S., Bains L., Khamees A., Ababneh H., Aljaiuossi O., Pimentel S., Mohamad I. S., Yusoff A. R., Zarnescu N. O., Calu V., Litvin A., Lesko D., Elmehrath A., Elshami M., de Santibanes M., Gundara J., Alawadhi K., Lui R., Julianov A., Ralon S., Garzali I. -U., Machain G. M., Villalabeitia I., Quispe-Cruz D. A., Orantia A. C. C., Waledziak M., de Sa T. C., Ali S. M., Kovacevic B., Noel C., Abdalah H. M., Kchaou A., Isik A., Ansaloni L., Biffl W., Guerrieri M., Sartori A., Abradelo M., Nigri G., Di Lorenzo N., Mingoli A., Chiarugi M., Di Menno Stavron J., Mazza O., Valenzuela J. I., Pachajoa D. A. P., Alvarez F. A., Liano J. E., Tefay J., Alshaikh A., Hasan L., Couto Gomes F., Calderan T. R. A., Hirano E. S., Dardanov D., Saroglu A., Atanasov B., Belev N., Kovachev N., Chan S. M., Lok H. -T., Salcedo D., Robayo D., Trivino M. A., Manak J., de Araujo J., Sethi A., Awad A., Elbadawy M., Farid A., Hanafy A., Nafea A., Sherief G., Salah Alzhraa A., Abdelsalam W., Emile S., Elfallal A., Elfeki H., Elghadban H., Shoma A., Shetiwy M., Elbahnasawy M., Mohamed S., Hamed E. F., Khalil U. A., Chouillard E., Gumbs A., Police A., Mabilia A., Khutsishvili K., Tvaladze A., Ioannidis O., Anestiadou E., Loutzidou L., Konstantinidis K., Konstantinidou S., Manatakis D., Acheimastos V., Tasis N., Michalopoulos N., Kokoropoulos P., Papadoliopoulou M., Sotiropoulou M., Kapiris S., Metaxas P., Tsouknidas I., Kefili D., Petrakis G., Synekidou E., Dakis K., Alexandridou E., Papadopoulos A., Chouliaras C., Mouzakis O., Mulita F., Maroulis I., Vailas M., Triantafyllou T., Theodorou D., Lostoridis E., Nagorni E. -A., Tourountzi P., Baili E., Charalabopoulos A., Liakakos T., Schizas D., Kozadinos A., Syllaios A., Machairas N., Kykalos S., Stamopoulos P., Delis S., Farazi-Chongouki C., Kalaitzakis E., Giannarakis M., Lasithiotakis K., Petra G., Gupta A., Medappil N., Muthukrishnan V., Kamar J., Lal P., Agarwal R., Magnoli M., Aonzo P., Serventi A., Di Lascio P., Pinto M., Bergamini C., Bottari A., Fortuna L., Martellucci J., Cicako A., Miglietta C., Morino M., Delogu D., Picchetto A., Assenza M., D'Ambrosio G., Argenio G., Armellino M. F., Ioia G., Occhionorelli S., Andreotti D., Domenico L., Luppi D., Casadei M., Di Donato L., Manoochehri F., Marchese T. R. L., Sergi W., Manca R., Murgia R., Piras E., Conti L., Gianazza S., Rizzi A., Segalini E., Monti M., Iiritano E., Mariani N. M., De Nicola E., Scifo G., Pignata G., Andreuccetti J., Fleres F., Clarizia G., Spolini A., Biloslavo A., Germani P., Mastronardi M., Bogoni S., Palmisano S., De Manzini N., Marino M. V., Martines G., Trigiante G., Lagouvardou E., Anania G., Bombardini C., Oppici D., Pilia T., Murzi V., Gessa E., Bracale U., Di Nuzzo M. M., Peltrini R., Salvetti F., Vigano J., Sganga G., Bianchi V., Fransvea P., Fontana T., Sarro G., Dinuzzi V. P., Scaravilli L., Papa M. V., Jovine E., Ciabatti G., Mastrangelo L., Rottoli M., Ricci C., Russo I. S., Aiolfi A., Bona D., Lombardo F., Cianci P., Sederino M., Bini R., Chiara O., Cioffi S., Cantafio S., Coretti G., Licitra E., Savino G., Grimaldi S., Porfidia R., Moggia E., Garino M., Marafante C., Pesce A., Fabbri N., Feo C. V., Marra E., Troian M., Drigo D., Nagliati C., Muratore A., Danna R., Murgese A., Crespi M., Guerci C., Frontali A., Ferrari L., Favi F., Picariello E., Rampini A., D'Acapito F., Ercolani G., Solaini L., Palmieri F., Cali M., Ferrara F., Muttillo I. A., Muttillo E. M., Picardi B., Galleano R., Badran A., Ghazouani O., Cervellera M., Campanella G., Papa G., Di Bella A., Perrone G., Petracca G. L., Prioriello C., Giuffrida M., Cozzani F., Rossini M., Inama M., Butturini G., Moretto G., Morelli L., Candio G., Guadagni S., Cicuttin E., Cremonini C., Tartaglia D., Genovese V., Cillara N., Cannavera A., Deserra A., Picciariello A., Papagni V., Vincenti L., Bagaglini G., Sica G., Lapolla P., Brachini G., Bono D., Nicotera A., Zago M., Sammartano F., Benuzzi L., Stella M., Rossi S., Cerioli A., Puccioni C., Olmi S., Rubicondo C., Uccelli M., Guida A., Lepiane P., Sasia D., Giraudo G., Salomone S., Belloni E., Cossa A., Lancellotti F., Caronna R., Chirletti P., Saullo P., Troiano R., Mucilli F., Barone M., Ippoliti M., Grande M., Sensi B., Siragusa L., Santini A., Di Carlo I., Veroux M., Gioco R., Veroux G., Curro G., Ammendola M., Komaei I., Navarra G., Tonini V., Sartarelli L., Ceresoli M., Perrone S., Roccamatisi L., Millo P., Brachet Contul R., Ponte E., Zuin M., Portale G., Tonello A. S., Fratini G., Bianchini M., Perotti B., Doria E., Lunghi E. G., Visconti D., Al-Shami K., Awadi S., Buwaitel M. M. K., Naffa' M. F. N., Samhouri A., Sawalha H., Ani M. F. C., Fathil I. N. A., Huei J., Beristain-Hernandez J. -L., Garcia-Meza A., Sepulveda-Rdriguez R., Hernandez E. E. L., Pinzon C. L. A., Condoy J. N., Garcia F. C. B., Sadik M., Kadir B., Devi J., Seerani N., Sohail-Asghar M., Afzal A., Akbar A., Lohse H. S., Cabrera Z. S. L., Seto G. S. Y., Chiuyari J. R., Ordemar J., Rodriguez M., Orantia-Carlos A. C. C., Quitoy M. A., Kwiatkowski A., Mawlichanow M., Rocha M., Soares C., Stoian A. R., Draghici A. D., Grigorean V. T., Radulescu R. B., Costea R. V., Zarnescu E. C., Kurtenkov M., Gendrikson G., Alla-Angelina V., Arina T., Kaldarov A., Gachabayov M., Abdullaev A., Milentijevic M., Karamarkovic M., Panyko A., Radonak J., Soltes M., Moran L. A., Garcia H. C., Vega P. S., Estevez S., Ausania F., Farguell J., Gonzalez-Abos C., Sanchez-Cabus S., Martin B., Molina V., Oms L., Ilzarbe L., Feijoo E. P., Perra E. S., Rojas-Bonet N., Penalba-Palmi R., Perez-Bru S., Tur-Martinez J., Alvarez-Torrado A., Domingo-Gonzalez M., Tejedor-Tejada J., del Alamo Y. G., Mendoza-Moreno F., Garcia-Moreno-Nisa F., Matias-Garcia B., Duran M., Calleja-Lozano R., de Villar J. M. P., Sanchez-Guillen L., Caravaca I., Triguero-Canovas D., Aparicio A. C. M., Melendez B. D., Palacios A. M., Landaluce-Olavarria A., De Francisco M., Estraviz-Mateos B., Alconchel F., Nicolas-Lopez T., Ramirez P., Munoz-Cruzado V. D., Ciuro F. P., del Pozo E. P., Pizarro S. O., Cabrera V. H., Bayo J. M., Hamid H. K. S., Roesel R., Cristaudi A., Abbas K., Ali I., Tlili A., Bayhan H., Turkoglu M. A., Uzunoglu M. Y., Azamat I. F., Omarov N., Uymaz D. S., Altintoprak F., Akin E., First N., Das K., Ozer N., Seker A., Kara Y., Bozkurt M. A., Kocatas A., Atici S. D., Akalin M., Calik B., Colak E., Altinel Y., Meric S., Aktimur Y. E., Hudson V., Duval J. -L., Khan M., Saad A., Kaur M., Bradley A., Fox K., Tomasi I., Beasley D., Prasanti A. K., Kotecha P., Ebied H., Paul M., Sheth H., Gerogiannis I., Gaber M., Sheikh Z., Seth S., Kunitsyna M., Leo C. A., Bellato V., Zafar N., Elserafy A., Bond-smith G., Tebala G., Mathur P., Abid I., Chidumije N., Sandhar P., Ullah S. O. Z., Lezama T., Anwaar M. H., Magee C., Ahmed S., Davies B., Apollos J., McCormack K., Choudhary H., Doulias T., Morrison T., Palepa A., Cal F. B., Sanchez L., Dominguez F., Al-Raimi I., Alshargabi H., Meead A., Chooklin S., Chuklin S., Bilyak A., Podda, M, Pellino, G, Di Saverio, S, Coccolini, F, Pacella, D, Cioffi, S, Virdis, F, Balla, A, Ielpo, B, Pata, F, Poillucci, G, Ortenzi, M, Damaskos, D, De Simone, B, Sartelli, M, Leppaniemi, A, Jayant, K, Catena, F, Giuliani, A, Di Martino, M, Pisanu, A, Gerardi, C, Gourgiotis, S, Riboni, C, Giordano, A, Ferrario, L, Agnoletti, V, Kruger, Y, Mole, D, Agresta, F, Prieto Calvo, M, Wilson, M, Soggiu, F, Hamdan, A, Gomes, C, Fraga, G, Ioannidis, A, Demetrashvili, Z, Sahani, S, Bains, L, Khamees, A, Ababneh, H, Aljaiuossi, O, Pimentel, S, Mohamad, I, Yusoff, A, Zarnescu, N, Calu, V, Litvin, A, Lesko, D, Elmehrath, A, Elshami, M, de Santibanes, M, Gundara, J, Alawadhi, K, Lui, R, Julianov, A, Ralon, S, Garzali, I, Machain, G, Villalabeitia, I, Quispe-Cruz, D, Orantia, A, Waledziak, M, de Sa, T, Ali, S, Kovacevic, B, Noel, C, Abdalah, H, Kchaou, A, Isik, A, Ansaloni, L, Biffl, W, Guerrieri, M, Sartori, A, Abradelo, M, Nigri, G, Di Lorenzo, N, Mingoli, A, Chiarugi, M, Di Menno Stavron, J, Mazza, O, Valenzuela, J, Pachajoa, D, Alvarez, F, Liano, J, Tefay, J, Alshaikh, A, Hasan, L, Couto Gomes, F, Calderan, T, Hirano, E, Dardanov, D, Saroglu, A, Atanasov, B, Belev, N, Kovachev, N, Chan, S, Lok, H, Salcedo, D, Robayo, D, Trivino, M, Manak, J, de Araujo, J, Sethi, A, Awad, A, Elbadawy, M, Farid, A, Hanafy, A, Nafea, A, Sherief, G, Salah Alzhraa, A, Abdelsalam, W, Emile, S, Elfallal, A, Elfeki, H, Elghadban, H, Shoma, A, Shetiwy, M, Elbahnasawy, M, Mohamed, S, Hamed, E, Khalil, U, Chouillard, E, Gumbs, A, Police, A, Mabilia, A, Khutsishvili, K, Tvaladze, A, Ioannidis, O, Anestiadou, E, Loutzidou, L, Konstantinidis, K, Konstantinidou, S, Manatakis, D, Acheimastos, V, Tasis, N, Michalopoulos, N, Kokoropoulos, P, Papadoliopoulou, M, Sotiropoulou, M, Kapiris, S, Metaxas, P, Tsouknidas, I, Kefili, D, Petrakis, G, Synekidou, E, Dakis, K, Alexandridou, E, Papadopoulos, A, Chouliaras, C, Mouzakis, O, Mulita, F, Maroulis, I, Vailas, M, Triantafyllou, T, Theodorou, D, Lostoridis, E, Nagorni, E, Tourountzi, P, Baili, E, Charalabopoulos, A, Liakakos, T, Schizas, D, Kozadinos, A, Syllaios, A, Machairas, N, Kykalos, S, Stamopoulos, P, Delis, S, Farazi-Chongouki, C, Kalaitzakis, E, Giannarakis, M, Lasithiotakis, K, Petra, G, Gupta, A, Medappil, N, Muthukrishnan, V, Kamar, J, Lal, P, Agarwal, R, Magnoli, M, Aonzo, P, Serventi, A, Di Lascio, P, Pinto, M, Bergamini, C, Bottari, A, Fortuna, L, Martellucci, J, Cicako, A, Miglietta, C, Morino, M, Delogu, D, Picchetto, A, Assenza, M, D'Ambrosio, G, Argenio, G, Armellino, M, Ioia, G, Occhionorelli, S, Andreotti, D, Domenico, L, Luppi, D, Casadei, M, Di Donato, L, Manoochehri, F, Marchese, T, Sergi, W, Manca, R, Murgia, R, Piras, E, Conti, L, Gianazza, S, Rizzi, A, Segalini, E, Monti, M, Iiritano, E, Mariani, N, De Nicola, E, Scifo, G, Pignata, G, Andreuccetti, J, Fleres, F, Clarizia, G, Spolini, A, Biloslavo, A, 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Al-Shami, K, Awadi, S, Buwaitel, M, Naffa', M, Samhouri, A, Sawalha, H, Ani, M, Fathil, I, Huei, J, Beristain-Hernandez, J, Garcia-Meza, A, Sepulveda-Rdriguez, R, Hernandez, E, Pinzon, C, Condoy, J, Garcia, F, Sadik, M, Kadir, B, Devi, J, Seerani, N, Zainab, Sohail-Asghar, M, Afzal, A, Akbar, A, Lohse, H, Cabrera, Z, Seto, G, Chiuyari, J, Ordemar, J, Rodriguez, M, Orantia-Carlos, A, Quitoy, M, Kwiatkowski, A, Mawlichanow, M, Rocha, M, Soares, C, Stoian, A, Draghici, A, Grigorean, V, Radulescu, R, Costea, R, Zarnescu, E, Kurtenkov, M, Gendrikson, G, Alla-Angelina, V, Arina, T, Kaldarov, A, Gachabayov, M, Abdullaev, A, Milentijevic, M, Karamarkovic, M, Panyko, A, Radonak, J, Soltes, M, Moran, L, Garcia, H, Vega, P, Estevez, S, Ausania, F, Farguell, J, Gonzalez-Abos, C, Sanchez-Cabus, S, Martin, B, Molina, V, Oms, L, Ilzarbe, L, Feijoo, E, Perra, E, Rojas-Bonet, N, Penalba-Palmi, R, Perez-Bru, S, Tur-Martinez, J, Alvarez-Torrado, A, Domingo-Gonzalez, M, Tejedor-Tejada, J, del Alamo, Y, Mendoza-Moreno, F, Garcia-Moreno-Nisa, F, Matias-Garcia, B, Duran, M, Calleja-Lozano, R, de Villar, J, Sanchez-Guillen, L, Caravaca, I, Triguero-Canovas, D, Aparicio, A, Melendez, B, Palacios, A, Landaluce-Olavarria, A, De Francisco, M, Estraviz-Mateos, B, Alconchel, F, Nicolas-Lopez, T, Ramirez, P, Munoz-Cruzado, V, Ciuro, F, del Pozo, E, Pizarro, S, Cabrera, V, Bayo, J, Hamid, H, Roesel, R, Cristaudi, A, Abbas, K, Ali, I, Tlili, A, Bayhan, H, Turkoglu, M, Uzunoglu, M, Azamat, I, Omarov, N, Uymaz, D, Altintoprak, F, Akin, E, First, N, Das, K, Ozer, N, Seker, A, Kara, Y, Bozkurt, M, Kocatas, A, Atici, S, Akalin, M, Calik, B, Colak, E, Altinel, Y, Meric, S, Aktimur, Y, Hudson, V, Duval, J, Khan, M, Saad, A, Kaur, M, Bradley, A, Fox, K, Tomasi, I, Beasley, D, Prasanti, A, Kotecha, P, Ebied, H, Paul, M, Sheth, H, Gerogiannis, I, Gaber, M, Sheikh, Z, Seth, S, Kunitsyna, M, Leo, C, Bellato, V, Zafar, N, Elserafy, A, Bond-smith, G, Tebala, G, Mathur, P, Abid, I, Chidumije, N, Sandhar, P, Ullah, S, Lezama, T, Anwaar, M, Magee, C, Ahmed, S, Davies, B, Apollos, J, Mccormack, K, Choudhary, H, Doulias, T, Morrison, T, Palepa, A, Cal, F, Sanchez, L, Dominguez, F, Al-Raimi, I, Alshargabi, H, Meead, A, Chooklin, S, Chuklin, S, Bilyak, A, Podda M., Pellino G., Di Saverio S., Coccolini F., Pacella D., Cioffi S. P. B., Virdis F., Balla A., Ielpo B., Pata F., Poillucci G., Ortenzi M., Damaskos D., De Simone B., Sartelli M., Leppaniemi A., Jayant K., Catena F., Giuliani A., Di Martino M., Pisanu A., Gerardi C., Gourgiotis S., Riboni C., Giordano A., Ferrario L., Agnoletti V., Kruger Y., Mole D., Agresta F., Prieto Calvo M., Wilson M., Soggiu F., Hamdan A., Gomes C. A., Fraga G., Ioannidis A., Demetrashvili Z., Sahani S., Bains L., Khamees A., Ababneh H., Aljaiuossi O., Pimentel S., Mohamad I. S., Yusoff A. R., Zarnescu N. O., Calu V., Litvin A., Lesko D., Elmehrath A., Elshami M., de Santibanes M., Gundara J., Alawadhi K., Lui R., Julianov A., Ralon S., Garzali I. -U., Machain G. M., Villalabeitia I., Quispe-Cruz D. A., Orantia A. C. C., Waledziak M., de Sa T. C., Ali S. M., Kovacevic B., Noel C., Abdalah H. M., Kchaou A., Isik A., Ansaloni L., Biffl W., Guerrieri M., Sartori A., Abradelo M., Nigri G., Di Lorenzo N., Mingoli A., Chiarugi M., Di Menno Stavron J., Mazza O., Valenzuela J. I., Pachajoa D. A. P., Alvarez F. A., Liano J. E., Tefay J., Alshaikh A., Hasan L., Couto Gomes F., Calderan T. R. A., Hirano E. S., Dardanov D., Saroglu A., Atanasov B., Belev N., Kovachev N., Chan S. M., Lok H. -T., Salcedo D., Robayo D., Trivino M. A., Manak J., de Araujo J., Sethi A., Awad A., Elbadawy M., Farid A., Hanafy A., Nafea A., Sherief G., Salah Alzhraa A., Abdelsalam W., Emile S., Elfallal A., Elfeki H., Elghadban H., Shoma A., Shetiwy M., Elbahnasawy M., Mohamed S., Hamed E. F., Khalil U. A., Chouillard E., Gumbs A., Police A., Mabilia A., Khutsishvili K., Tvaladze A., Ioannidis O., Anestiadou E., Loutzidou L., Konstantinidis K., Konstantinidou S., Manatakis D., Acheimastos V., Tasis N., Michalopoulos N., Kokoropoulos P., Papadoliopoulou M., Sotiropoulou M., Kapiris S., Metaxas P., Tsouknidas I., Kefili D., Petrakis G., Synekidou E., Dakis K., Alexandridou E., Papadopoulos A., Chouliaras C., Mouzakis O., Mulita F., Maroulis I., Vailas M., Triantafyllou T., Theodorou D., Lostoridis E., Nagorni E. -A., Tourountzi P., Baili E., Charalabopoulos A., Liakakos T., Schizas D., Kozadinos A., Syllaios A., Machairas N., Kykalos S., Stamopoulos P., Delis S., Farazi-Chongouki C., Kalaitzakis E., Giannarakis M., Lasithiotakis K., Petra G., Gupta A., Medappil N., Muthukrishnan V., Kamar J., Lal P., Agarwal R., Magnoli M., Aonzo P., Serventi A., Di Lascio P., Pinto M., Bergamini C., Bottari A., Fortuna L., Martellucci J., Cicako A., Miglietta C., Morino M., Delogu D., Picchetto A., Assenza M., D'Ambrosio G., Argenio G., Armellino M. F., Ioia G., Occhionorelli S., Andreotti D., Domenico L., Luppi D., Casadei M., Di Donato L., Manoochehri F., Marchese T. R. L., Sergi W., Manca R., Murgia R., Piras E., Conti L., Gianazza S., Rizzi A., Segalini E., Monti M., Iiritano E., Mariani N. M., De Nicola E., Scifo G., Pignata G., Andreuccetti J., Fleres F., Clarizia G., Spolini A., Biloslavo A., Germani P., Mastronardi M., Bogoni S., Palmisano S., De Manzini N., Marino M. V., Martines G., Trigiante G., Lagouvardou E., Anania G., Bombardini C., Oppici D., Pilia T., Murzi V., Gessa E., Bracale U., Di Nuzzo M. M., Peltrini R., Salvetti F., Vigano J., Sganga G., Bianchi V., Fransvea P., Fontana T., Sarro G., Dinuzzi V. P., Scaravilli L., Papa M. V., Jovine E., Ciabatti G., Mastrangelo L., Rottoli M., Ricci C., Russo I. S., Aiolfi A., Bona D., Lombardo F., Cianci P., Sederino M., Bini R., Chiara O., Cioffi S., Cantafio S., Coretti G., Licitra E., Savino G., Grimaldi S., Porfidia R., Moggia E., Garino M., Marafante C., Pesce A., Fabbri N., Feo C. V., Marra E., Troian M., Drigo D., Nagliati C., Muratore A., Danna R., Murgese A., Crespi M., Guerci C., Frontali A., Ferrari L., Favi F., Picariello E., Rampini A., D'Acapito F., Ercolani G., Solaini L., Palmieri F., Cali M., Ferrara F., Muttillo I. A., Muttillo E. M., Picardi B., Galleano R., Badran A., Ghazouani O., Cervellera M., Campanella G., Papa G., Di Bella A., Perrone G., Petracca G. L., Prioriello C., Giuffrida M., Cozzani F., Rossini M., Inama M., Butturini G., Moretto G., Morelli L., Candio G., Guadagni S., Cicuttin E., Cremonini C., Tartaglia D., Genovese V., Cillara N., Cannavera A., Deserra A., Picciariello A., Papagni V., Vincenti L., Bagaglini G., Sica G., Lapolla P., Brachini G., Bono D., Nicotera A., Zago M., Sammartano F., Benuzzi L., Stella M., Rossi S., Cerioli A., Puccioni C., Olmi S., Rubicondo C., Uccelli M., Guida A., Lepiane P., Sasia D., Giraudo G., Salomone S., Belloni E., Cossa A., Lancellotti F., Caronna R., Chirletti P., Saullo P., Troiano R., Mucilli F., Barone M., Ippoliti M., Grande M., Sensi B., Siragusa L., Santini A., Di Carlo I., Veroux M., Gioco R., Veroux G., Curro G., Ammendola M., Komaei I., Navarra G., Tonini V., Sartarelli L., Ceresoli M., Perrone S., Roccamatisi L., Millo P., Brachet Contul R., Ponte E., Zuin M., Portale G., Tonello A. S., Fratini G., Bianchini M., Perotti B., Doria E., Lunghi E. 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S., Rojas-Bonet N., Penalba-Palmi R., Perez-Bru S., Tur-Martinez J., Alvarez-Torrado A., Domingo-Gonzalez M., Tejedor-Tejada J., del Alamo Y. G., Mendoza-Moreno F., Garcia-Moreno-Nisa F., Matias-Garcia B., Duran M., Calleja-Lozano R., de Villar J. M. P., Sanchez-Guillen L., Caravaca I., Triguero-Canovas D., Aparicio A. C. M., Melendez B. D., Palacios A. M., Landaluce-Olavarria A., De Francisco M., Estraviz-Mateos B., Alconchel F., Nicolas-Lopez T., Ramirez P., Munoz-Cruzado V. D., Ciuro F. P., del Pozo E. P., Pizarro S. O., Cabrera V. H., Bayo J. M., Hamid H. K. S., Roesel R., Cristaudi A., Abbas K., Ali I., Tlili A., Bayhan H., Turkoglu M. A., Uzunoglu M. Y., Azamat I. F., Omarov N., Uymaz D. S., Altintoprak F., Akin E., First N., Das K., Ozer N., Seker A., Kara Y., Bozkurt M. A., Kocatas A., Atici S. D., Akalin M., Calik B., Colak E., Altinel Y., Meric S., Aktimur Y. E., Hudson V., Duval J. -L., Khan M., Saad A., Kaur M., Bradley A., Fox K., Tomasi I., Beasley D., Prasanti A. K., Kotecha P., Ebied H., Paul M., Sheth H., Gerogiannis I., Gaber M., Sheikh Z., Seth S., Kunitsyna M., Leo C. A., Bellato V., Zafar N., Elserafy A., Bond-smith G., Tebala G., Mathur P., Abid I., Chidumije N., Sandhar P., Ullah S. O. Z., Lezama T., Anwaar M. H., Magee C., Ahmed S., Davies B., Apollos J., McCormack K., Choudhary H., Doulias T., Morrison T., Palepa A., Cal F. B., Sanchez L., Dominguez F., Al-Raimi I., Alshargabi H., Meead A., Chooklin S., Chuklin S., and Bilyak A.
- Abstract
The identification of high-risk patients in the early stages of infected pancreatic necrosis (IPN) is critical, because it could help the clinicians to adopt more effective management strategies. We conducted a post hoc analysis of the MANCTRA-1 international study to assess the association between clinical risk factors and mortality among adult patients with IPN. Univariable and multivariable logistic regression models were used to identify prognostic factors of mortality. We identified 247 consecutive patients with IPN hospitalised between January 2019 and December 2020. History of uncontrolled arterial hypertension (p = 0.032; 95% CI 1.135–15.882; aOR 4.245), qSOFA (p = 0.005; 95% CI 1.359–5.879; aOR 2.828), renal failure (p = 0.022; 95% CI 1.138–5.442; aOR 2.489), and haemodynamic failure (p = 0.018; 95% CI 1.184–5.978; aOR 2.661), were identified as independent predictors of mortality in IPN patients. Cholangitis (p = 0.003; 95% CI 1.598–9.930; aOR 3.983), abdominal compartment syndrome (p = 0.032; 95% CI 1.090–6.967; aOR 2.735), and gastrointestinal/intra-abdominal bleeding (p = 0.009; 95% CI 1.286–5.712; aOR 2.710) were independently associated with the risk of mortality. Upfront open surgical necrosectomy was strongly associated with the risk of mortality (p < 0.001; 95% CI 1.912–7.442; aOR 3.772), whereas endoscopic drainage of pancreatic necrosis (p = 0.018; 95% CI 0.138–0.834; aOR 0.339) and enteral nutrition (p = 0.003; 95% CI 0.143–0.716; aOR 0.320) were found as protective factors. Organ failure, acute cholangitis, and upfront open surgical necrosectomy were the most significant predictors of mortality. Our study confirmed that, even in a subgroup of particularly ill patients such as those with IPN, upfront open surgery should be avoided as much as possible.
- Published
- 2023
15. Safety and efficacy of intraperitoneal drain placement after emergency colorectal surgery: An international, prospective cohort study
- Author
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L., Izzo F., Delrio P., Restini E., Chetta G., Lantone G., Ferrari G., Lucchi A., De Prizio M., Caristo G., Borghi F., Petrucciani N., Huscher C., Cocorullo G., Tonini V., Medas F., Sica G., Cillara N., Anastasi A., Bianco F., Giuliani A., Carlini M., Selvaggi F., Sammarco G., Ozolins A., Malasonoks A., Andrejevic P., Tanis P., van de Ven A., Gerhards M., Ribeiro da Silva B., Silva A., Lima M. J., Kavanagh D., McCawley N., Bintintan V., Karamarkovic A., Sanz Ortega G., De Andres-Asenjo B., Nevado Garcia C., Garcia Florez L. J., Segura-Sampedro J. J., Blas Laina J. L., Ponchietti L., Buchwald P., Gialamas E., Ozben V., Rencuzogullari A., Gecim I. E., Altinel Y., Isik O., Yoldas T., Isik A., Leventoglu S., Erturk M. S., Guner A., Guler S. A., Attaallah W., Ugur M., Ozbalci G. S., Marzook H., Eardley N., Smolarek S., Morgan R., Roxburgh C., Lala A. 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F., Gazo Martinez J., Vicario Bravo M., Chavarrias N., Gil Catalan A., Oseira A., Villalonga B., Jeri S., Perez Calvo J., Nogues A., Cros B., Yanez C., Utrilla Fornals A., Roldon Golet M., Colsa P., Gimenez Maurel T., Axmarker T., Chevallay M., Pham T. V., Sel E. K., Atar C., Aba M., Sarkin M., Akkaya Y. M., Durmaz A. G., Gullu H. F., Boga A., Aktas A., Bakar B., Demirel M. T., Hysejni X., Taser M., Guzel O. R., Bozbiyik O., Ozen D., Olmez M., Uyar B., Gulcek E., Kayacan G. S., Atici N., Gul O. F., Altiner S., Ibis B., Altunsu S., Banaz T., Diler C., Demirbas I., Usta M. A., Erkul O., Orman R., Salih S., Utkan N. Z., Acil C., Ozgur E., Maddahali M., Turhan A. B., Eskici A. B., Ular B., Dogru M., Ozturk O. U., Arslan E. R., Panahi Sharif A., Dikmen E., Ates J., Bircan R., Cavus T., Sever A. E., Balak B., Duman E., Altay L., Emanet O., Cullen F., Tan J. Y., Nathan A., Rottenberg A., Williams C. Y., Mitrofan C. G., Xu D., Bawa J. H., Morris P., Gordon D., Richmond G., Hui J. 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A., Kurtenkov M., Jovanovic M., Vician M., Egea Arias P., Beltran de Heredia J., Labalde Martinez M., De Santiago Alvarez I., Alvarez-Gallego M., Rodriguez Artigas J. M., Dwidar O., Korkmaz H. K., Eray I. C., Meric S., Aydin R., Cetin B., Karaca B. E., Kuyumcu O. F., Yuksel E., Uprak T. K., Karabulut K., Kavukcu E., Mansor A., Hackett R., Zammit-Maempel M., Sabaratnam R., Maan A., Ferarrio I., Dixon L., Halai H., Sethi S., Nelson L., Grassam-rowe A., Krishnan E., Deeny D., McKeever M., George Pandeth A., Dhavala P., Sreenivasan S., Sundaram Venkatesan G., Zhu L., Atiyah Z., Gregory J., Morey T., Seymour Z., Holdsworth L., Abdelmahmoud S., Bourhill J., Bisheet G., Shaw J., Kulkarni K., Kumarakulasingam P., Pillay S., Al-Habsi R., Kungwengwe G., Richards J., Davoudi K., Ibrahim B., Tailor B., Zayed M., Chen F., Bailey S., Sheefat S., Nawaz G., Pawar R., Marsh S., Sam Z. H., Roy Bentley S., Simpson C., Hughes J., Lim Y., Ooi R., Toh W. H., Mannion P., Lovett A., Kincius A., Hussein S., Kirby E., Beckett R. G., Salmon J., Glynn T., Choo S. Y., Lyons S., Browne D., Ravindran W., Ahmad S., Zhu X., McNulty J., McCarthy L., Ng J., Karmally Z., McTeir K., Hanna M., Tan E., Namdeo S., Schembri R., and Pusey E.
- Abstract
Aim: Intraperitoneal drains are often placed during emergency colorectal surgery. However, there is a lack of evidence supporting their use. This study aimed to describe the efficacy and safety of intraperitoneal drain placement after emergency colorectal surgery. Method: COMPlicAted intra-abdominal collectionS after colorectal Surgery (COMPASS) is a prospective, international, cohort study into which consecutive adult patients undergoing emergency colorectal surgery were enrolled (from 3 February 2020 to 8 March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included rate and time-to-diagnosis of postoperative intraperitoneal collections, rate of surgical site infections (SSIs), time to discharge and 30-day major postoperative complications (Clavien–Dindo III–V). Multivariable logistic and Cox proportional hazards regressions were used to estimate the independent association of the outcomes with drain placement. Results: Some 725 patients (median age 68.0 years; 349 [48.1%] women) from 22 countries were included. The drain insertion rate was 53.7% (389 patients). Following multivariable adjustment, drains were not significantly associated with reduced rates (odds ratio [OR] = 1.56, 95% CI: 0.48–5.02, p = 0.457) or earlier detection (hazard ratio [HR] = 1.07, 95% CI: 0.61–1.90, p = 0.805) of collections. Drains were not significantly associated with worse major postoperative complications (OR = 1.26, 95% CI: 0.67–2.36, p = 0.478), delayed hospital discharge (HR = 1.11, 95% CI: 0.91–1.36, p = 0.303) or increased risk of SSIs (OR = 1.61, 95% CI: 0.87–2.99, p = 0.128). Conclusion: This is the first study investigating placement of intraperitoneal drains following emergency colorectal surgery. The safety and clinical benefit of drains remain uncertain. Equipoise exists for randomized trials to define the safety and efficacy of drains in emergency colorectal surgery.
- Published
- 2023
16. A study of the entanglement in systems with periodic boundary conditions
- Author
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Panagiotou, E., Tzoumanekas, C., Lambropoulou, S., Millett, K. C., and Theodorou, D. N.
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Mathematics - Geometric Topology ,Condensed Matter - Soft Condensed Matter - Abstract
We define the local periodic linking number, LK, between two oriented closed or open chains in a system with three-dimensional periodic boundary conditions. The properties of LK indicate that it is an appropriate measure of entanglement between a collection of chains in a periodic system. Using this measure of linking to assess the extent of entanglement in a polymer melt we study the effect of CReTA algorithm on the entanglement of polyethylene chains. Our numerical results show that the statistics of the local periodic linking number observed for polymer melts before and after the application of CReTA are the same., Comment: 11 pages, 11 figures
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- 2010
- Full Text
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17. Intraperitoneal drain placement and outcomes after elective colorectal surgery: International matched, prospective, cohort study
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C., Ighomereho O., Rocks R., McCabe S., Fitzpatrick A., Nicoletti J., Auterson L., Darrah N., Soh V. W. Y., Ong C. S., Utukuri M., Gallagher C., Stuart L. M., Hipolito M., Douglas N., Ghazal R., Parris G., Catchpole J., Bryden M., Jamal S., Karim Z., Lyon-Dean C., Rowley G., Lee K. S., Whitehurst O., Mirza A., Sheikh F., Yousaf H., Bilbao J., Sinclair R., Takar S., Kressel H., Chan V., Schack K., Osborne R., Baldemor S., Smyth S., Gilmour S., Ting A., Bozonelou I., Saunders P., Qhaireel Anwar Q. A., Tirimanna R., Jauhari S., Gardener A., Walker B., Wenban C., Reddy H., Conway-Jones R., Loganathan S., Clynch A., James C., Matey E., Cameron F., Roberts W., Gicquel A., Milliken C., Forbes J., Rubinchik P., Azmi A., Hawkes C., Cornett L., Adarkwah P., McConville R., O'Hara S., Tijare C., Parkes J., Yao L., Ahmad R., Shafiq U., Mhaisalkar A., Gurung A., de Stadler K., Elias S., Thomas T., Madras A., Jani A., Daler H. K., Tong K. S., Sundaralingam S. S., Szal A., Khan A., O'Sullivan C., Baker E., Joseph-Gubral J., Hadley E., Trivedi R., Igwelaezoh E., Barton H., Allison W., Hurst W., Alam F., Parkes I., Jamshaid M., Azizan N., Burgher T., Afzal A., Eltilib I., Zahid M., Sadiq O., Lloyd A., Ho R., Brazukas A., Li C. H., Kamdar M., Mohamed Nazeer M. N., Mighiu A., Kim D., Wilkins L., Kuo L., Rafe T., Maduka D., Cheema H., Farag K., Abdellatif M., Nzewi R., Kruczynska A., Grasselli H., Yousuff M., Bassi R., Mann A. K., Chopra J., Shaikh M., Sa D. S., Tsimplis V., Ghanchi A., Skene E., Asim K., Zaheer M., Chan S., Dalton H., Gibbons K., Adderley O., Chukwujindu I., Jayasuriya I., Sivanu K., Borumand M., Chick G., Bridges I., Tomlin J., McKenna J., Nandra N., Grieco C., Quek F. F., Mercer R., Brankin-Frisby T., Sattar A., Aslam A., Edelsten E., Shafi S., Kouli T., Ford V., Gurung F., Fernandes M., Deader N., Ponniah R., Jamieson S., Davies A., Taubwurcel J., Aung M. T., Desai R., Begum S., Jamadar T., Kangatharan A., Rzeszowski B., Ho C., Yap S. H. K., Prendergast M., Sethi R., Duku A., Lowe C., Bray J., Ghobrial M., Nichita V., Wagstaff A., Rengasamy E., Abu Hassan F., Mahmood H., Savill N., Shah S., Almeida T., Edwards A., Catchpole B., Halford Z., Carmichael A., Alsusa H., Boyd M., Williams J., Feyi-Waboso J., Patel M., Zeidan Z., Bailey E., Bapty J., Brazkiewicz M., Tremlett A., Pringle H., Mankal S., Chung W., Parry-Jones E., Anderson K., McForrester A., Stanley A., Hoather A., Wise H., Laid I., Scriven J., Braniste A., Wilson A., Le Blevec L., Pakunwanich N., Evans N., Chong H. L., White C., Hunter J., Haque M., Vanalia P., Murdoch S., Choudhary T., McCann A., Harun A., Shah H., Hunt S., Shafiq Y., Bickley-Morris E., Emms L., Dare M., Akula Y., Deliyannis E., Mayes F., Ellacott M., Zagorac Z., Farren A., Manning C., Hughed C., Stewart E. G., Lim K. H., Chohan N., Thaker A., Thompson B., Ahari D., Burdekin E., Okwu U., Akintunde A., Lhaf F., Douthwaite J., Govindan R., Leelamanthep S., Gull E., Wright F., Dundas L., Mackdermott N., Burchi-Khairy T., Campbell I., Walsh J., Yeo J. Y., Meehan S., Banerjee D., Fu M., Kawka M., Ali T., Hussain Z., Thomas C., Ahmad H., Moroney J., Yick C., Risquet R., Ntuiabane D., Shimato M., Khan M., Ilangovan S., Vaselli N. M., Smithers R., Uhanowita Marage R., Valnarov-Boulter A., Kayran J., Banerjee M., Parekh-Hill N., Hooper A., Bowen J., Jagdish R., McQuoid C., Khan N., O'Hare R., Jeffery S., Zahid A., Elsworth C., Walter L., Dhillon S., Rao S., Anthony A., Ashaye A., Phillips N., Faderani R., Pengelly S., Choi S., Kwak S. Y., Lau Y. H. L., Bagheri K., Ong D. Y. C., Kerr E., Falconer K., Clancy N., Douglas S., Zhang Y., Greenfield F., Mutanga I., McAlinden J., Willis L., Adefolaju A., Agarwal H., Barter R., Harris G., Spencer G., Lee M. W., Vadiveloo V. T., Herbert G., Patel R., Shah M., El Falaha S., Wong C., Soare C., Akram J., Bozhkova L., Ma Y., Vo U. G., Tan H. W. N., Leto L., Kamal M. A., Hadzhieva E., Krastev P., Tonchev P., Kokkinos G., Pozotou I., Sabbagh D., Votava J., St F., Koliakos N., Tsaparas P., Zografos G., Mantas D., Tsourouflis G., Fradelos E., Trigiante G., Labellarte G., Resta G., Capelli G., D'Amore A., Verlingieri V., Campagnaro T., Maffioli A., Viscosi F., De Lucia C., Meneghini S., Fancellu A., Colella M., Biondi A., De Peppo V., Pace U., Albino V., Gattulli D., Piangerelli A., Kalivaci D., Sisto G., Mazzola M., Caneparo A., Lunghi E. G., Nespoli L. C., Angrisani M., Langone A., Gelarda E., Virgilio E., Angelini E., Fornasier C., Asero S., Filippone E., Frongia F., Calo P. G., Panaccio P., Ipponi P., Gili S., Braccio B., Tiesi V., Stolcers K., Kokaine L., Novikovs V., Capel L., Bastiaenen V., Heijmans H., Henriques S., Gan S. Z., Ramanayake H., Nolan M., Temperley H., Ciofic E., Pop B. A., Kurtenkov M., Jovanovic M., Vician M., Egea Arias P., Beltran de Heredia J., Labalde Martinez M., De Santiago Alvarez I., Alvarez-Gallego M., Rodriguez Artigas J. M., Dwidar O., Korkmaz H. K., Eray I. C., Meric S., Aydin R., Cetin B., Karaca B. E., Kuyumcu O. F., Yuksel E., Uprak T. K., Karabulut K., Kavukcu E., Mansor A., Hackett R., Zammit-Maempel M., Sabaratnam R., Maan A., Ferarrio I., Dixon L., Halai H., Sethi S., Nelson L., Grassam-Rowe A., Krishnan E., Deeny D., McKeever M., George Pandeth A., Dhavala P., Sreenivasan S., Sundaram Venkatesan G., Zhu L., Atiyah Z., Gregory J., Morey T., Seymour Z., Holdsworth L., Abdelmahmoud S., Bourhill J., Bisheet G., Shaw J., Kulkarni K., Kumarakulasingam P., Pillay S., Al-Habsi R., Kungwengwe G., Richards J., Davoudi K., Ibrahim B., Tailor B., Zayed M., Chen F., Bailey S., Sheefat S., Nawaz G., Pawar R., Marsh S., Sam Z. H., Roy Bentley S., Simpson C., Hughes J., Lim Y., Ooi R., Toh W. H., Mannion P., Lovett A., Kincius A., Hussein S., Kirby E., Beckett R. G., Salmon J., Glynn T., Choo S. Y., Lyons S., Browne D., Ravindran W., Ahmad S., Zhu X., McNulty J., McCarthy L., Ng J., Karmally Z., McTeir K., Hanna M., Tan E., Namdeo S., Schembri R., and Pusey E.
- Abstract
Despite current guidelines, intraperitoneal drain placement after elective colorectal surgery remains widespread. Drains were not associated with earlier detection of intraperitoneal collections, but were associated with prolonged hospital stay and increased risk of surgical-site infections.Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien-Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P < 0.001) and an increased risk of S
- Published
- 2022
18. OC-102 NUCK HYDROCELE DURING INGUINAL HERNIA REPAIR IN ADULT FEMALES. REPORT OF TWO CASES
- Author
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Chamzin, A, primary, Galyfos, G, additional, Triantafyllou, A, additional, Theodoropoulos, C, additional, Toutouzas, K, additional, Theodorou, D, additional, and Zografos, G, additional
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- 2023
- Full Text
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19. P-036 SUTURING OF THE INTERNAL INGUINAL ORIFICE DURING THE LAPAROSCOPIC TRANSABDOMINAL REPAIR OF A LARGE INDIRECT INGUINAL HERNIA
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Chamzin, A, primary, Galyfos, G, additional, Theodoropoulos, C, additional, Triantafyllou, A, additional, Toutouzas, K, additional, Theodorou, D, additional, and Zografos, G, additional
- Published
- 2023
- Full Text
- View/download PDF
20. Postoperative and Pathological Outcomes of CROSS and FLOT as Neoadjuvant Therapy for Esophageal and Junctional Adenocarcinoma: An International Cohort Study From the Oesophagogastric Anastomosis Audit (OGAA)
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MS CGO, Cancer, Steering Committee, Committee, Alderson, D., Bundred, J., Rpt, Evans, Gossage, J., Griffiths, E. A., Jefferies, B., Kamarajah, S. K., McKay, S., Mohamed, Nepogodiev, D., Siaw- Acheampong, K., Singh, P., Van Hillegersberg, R., Vohra, R., Wanigasooriya, K., Whitehouse, T., National Leads, Leads, Gjata, A., Moreno, J. I., Takeda, F. R., Kidane, B., Guevara Castro, R., Harustiak, T., Bekele, A., Kechagias, A., Gockel, Kennedy, A., Da Roit, A., Bagajevas, A., Azagra, J. S., Mahendran, H. A., Mejía-Fernández, L., Wijnhoven, B. P.L., El Kafsi, J., Sayyed, R. H., Sousa, M., Sampaio, A. S., Negoi, Blanco, R., Wallner, B., Schneider, P. M., Hsu, P. K., Isik, A., Leads, Site, Gananadha, S., Wills, Devadas, M., Duong, C., Talbot, M., Hii, M. W., Jacobs, R., Andreollo, N. A., Johnston, B., Darling, G., Isaza-Restrepo, A., Rosero, G., Arias-Amézquita, F., Raptis, D., Gaedcke, J., Reim, D., Izbicki, J., Egberts, J. H., Dikinis, S., Kjaer, D. W., Larsen, M. H., Achiam, M. P., Saarnio, J., Theodorou, D., Liakakos, T., Korkolis, D. P., Robb, W. B., Collins, C., Murphy, T., Reynolds, J., Tonini, Migliore, M., Bonavina, L., Valmasoni, M., Bardini, R., Weindelmayer, J., Terashima, M., White, R. E., Alghunaim, E., Elhadi, M., Leon-Takahashi, A. M., Medina-Franco, H., Lau, P. C., Okonta, K. E., Heisterkamp, J., Rosman, C., Beban, G., Babor, R., Gordon, A., Rossaak, J. I., Pal, K. M.I., Qureshi, A. U., Naqi, S. A., Syed, A. A., Barbosa, J., Vicente, C. S., Leite, J., Freire, J., Casaca, R., Costa, R. C.T., Scurtu, R. R., Mogoanta, S. S., Bolca, C., Constantinoiu, S., Sekhniaidze, D., Bjelović, M., So, J. B.Y., Gačevski, G., Loureiro, C., Pera, M., Bianchi, A., Moreno Gijón, M., Martín Fernández, J., Trugeda Carrera, M. S., Vallve-Bernal, M., Cítores Pascual, M. A., Elmahi, S., Halldestam, Hedberg, J., Mönig, S., Gutknecht, S., Tez, M., Guner, A., Tirnaksiz, M. B., Colak, E., Sevinç, B., Hindmarsh, A., Khan, Khoo, D., Byrom, R., Gokhale, J., Wilkerson, P., Jain, P., Chan, D., Robertson, K., Iftikhar, S., Skipworth, R., Forshaw, M., Higgs, S., Nijjar, R., Viswanath, Y. K.S., Turner, P., Dexter, S., Boddy, A., Allum, W. H., Oglesby, S., Cheong, E., Beardsmore, D., Maynard, N., Berrisford, R., Mercer, S., Puig, S., Melhado, R., Kelty, C., Underwood, T., Dawas, K., Lewis, W., Al-Bahrani, A., Bryce, G., Thomas, M., Arndt, A. T., Palazzo, F., Meguid, R. A., Collaborators, Fergusson, J., Beenen, E., Mosse, C., Salim, J., Cheah, S., Wright, T., Cerdeira, M. P., McQuillan, P., Richardson, M., Liem, H., Spillane, J., Yacob, M., Albadawi, F., Thorpe, T., Dingle, A., Cabalag, C., Loi, K., Fisher, O. M., Ward, S., Read, M., Johnson, M., Bassari, R., Bui, H., Cecconello, Raa, Sallum, Da Rocha, J. R.M., Lopes, L. R., Tercioti, V., Jds, Coelho, Ferrer, J. A.P., Buduhan, G., Tan, L., Srinathan, S., Shea, P., Yeung, J., Allison, F., Carroll, P., Vargas-Barato, F., Gonzalez, F., Ortega, J., Nino-Torres, L., Beltrán-García, T. C., Castilla, L., Pineda, M., Bastidas, A., Gómez-Mayorga, J., Cortés, N., Cetares, C., Caceres, S., Duarte, S., Pazdro, A., Snajdauf, M., Faltova, H., Sevcikova, M., Mortensen, P. B., Katballe, N., Ingemann, T., Kruhlikava, Morten B., Ainswort, A. P., Stilling, N. M., Eckardt, J., Holm, J., Thorsteinsson, M., Siemsen, M., Brandt, B., Nega, B., Teferra, E., Tizazu, A., Kauppila, J. H., Koivukangas, V., Meriläinen, S., Gruetzmann, R., Krautz, C., Weber, G., Golcher, H., Emons, G., Azizian, A., Ebeling, M., Niebisch, S., Kreuser, N., Albanese, G., Hesse, J., Volovnik, L., Boecher, U., Reeh, M., Triantafyllou, S., Schizas, D., Michalinos, A., Balli, E., Mpoura, M., Charalabopoulos, A., Manatakis, D. K., Balalis, D., Bolger, J., Baban, C., Mastrosimone, A., McAnena, O., Quinn, A., Ó Súilleabháin, C. B., Hennessy, M. M., Ivanovski, Khizer, H., Ravi, N., Donlon, N., Cervellera, M., Vaccari, S., Bianchini, S., Sartarelli, L., Asti, E., Bernardi, D., Merigliano, S., Provenzano, L., Scarpa, M., Saadeh, L., Salmaso, B., De Manzoni, G., Giacopuzzi, S., La Mendola, R., De Pasqual, C. A., Tsubosa, Y., Niihara, M., Irino, T., Makuuchi, R., Ishii, K., Mwachiro, M., Fekadu, A., Odera, A., Mwachiro, E., Alshehab, D., Ahmed, H. A., Shebani, A. O., Elhadi, A., Elnagar, F. A., Elnagar, H. F., Makkai-Popa, S. T., Wong, L. F., Tan, Y. R., Thannimalai, S., Ho, C. A., Pang, W. S., Tan, J. H., Hnl, Basave, Cortés-González, R., Lagarde, S. M., Van Lanschot, J. J.B., Cords, C., Jansen, W. A., Martijnse, I., Matthijsen, R., Bouwense, S., Klarenbeek, B., Verstegen, M., Van Workum, F., Ruurda, J. P., Van Der Sluis, P. C., De Maat, M., Evenett, N., Johnston, P., Patel, R., MacCormick, A., Young, M., Smith, B., Ekwunife, C., Memon, A. H., Shaikh, K., Wajid, A., Khalil, N., Haris, M., Mirza, Z. U., Sba, Qudus, Sarwar, M. Z., Shehzadi, A., Raza, A., Jhanzaib, M. H., Farmanali, J., Zakir, Z., Shakeel, O., Nasir, Khattak, S., Baig, M., Noor, M. A., Ahmed, H. H., Naeem, A., Pinho, A. C., Da Silva, R., Bernardes, A., Campos, J. C., Matos, H., Braga, T., Monteiro, C., Ramos, P., Cabral, F., Gomes, M. P., Martins, P. C., Correia, A. M., Videira, J. F., Ciuce, C., Drasovean, R., Apostu, R., Paitici, S., Racu, A. E., Obleaga, C. V., Beuran, M., Stoica, B., Negoita, Ciubotaru C., Cordos, Birla, R. D., Predescu, D., Hoara, P. A., Tomsa, R., Shneider, Agasiev, M., Ganjara, Gunjić, D., Veselinović, M., Babič, T., Chin, T. S., Shabbir, A., Kim, G., Crnjac, A., Samo, H., Díez Del Val, Del Val, Leturio, S., Ramón, J. M., Dal Cero, M., Rifá, S., Rico, M., Pagan Pomar, A., Martinez Corcoles, J. A., Rodicio Miravalles, J. L., Pais, S. A., Turienzo, S. A., Alvarez, L. S., Campos, P. V., Rendo, A. G., García, S. S., Epg, Santos, Martínez, E. T., Fernández Díaz, M. J., Magadán Álvarez, C., Martín, Concepción, Díaz López, C., Rosat Rodrigo, A., Pérez Sánchez, L. E., Bailón Cuadrado, M., Tinoco Carrasco, C., Choolani Bhojwani, E., Sánchez, D. P., Ahmed, M. E., Dzhendov, T., Lindberg, F., Rutegård, M., Sundbom, M., Mickael, C., Colucci, N., Schnider, A., Er, S., Kurnaz, E., Turkyilmaz, S., Turkyilmaz, A., Yildirim, R., Baki, B. E., Akkapulu, N., Karahan, O., Damburaci, N., Hardwick, R., Safranek, P., Sujendran, Bennett, J., Afzal, Z., Shrotri, M., Chan, B., Exarchou, K., Gilbert, T., Amalesh, T., Mukherjee, D., Mukherjee, S., Wiggins, T. H., Kennedy, R., McCain, S., Harris, A., Dobson, G., Davies, N., Wilson, I., Mayo, D., Bennett, D., Young, R., Manby, P., Blencowe, N., Schiller, M., Byrne, B., Mitton, D., Wong, V., Elshaer, A., Cowen, M., Menon, Tan, L. C., McLaughlin, E., Koshy, R., Sharp, C., Brewer, H., Das, N., Cox, M., Al Khyatt, W., Worku, D., Iqbal, R., Walls, L., McGregor, R., Fullarton, G., MacDonald, A., MacKay, C., Craig, C., Dwerryhouse, S., Hornby, S., Jaunoo, S., Wadley, M., Baker, C., Saad, M., Kelly, M., Davies, A., Di Maggio, F., Mistry, P., Singhal, R., Tucker, O., Kapoulas, S., Powell-Brett, S., Davis, P., Bromley, G., Watson, L., Verma, R., Ward, J., Shetty, V., Ball, C., Pursnani, K., Sarela, A., Sue Ling, H., Mehta, S., Hayden, J., To, N., Palser, T., Hunter, D., Supramaniam, K., Butt, Z., Ahmed, A., Kumar, S., Chaudry, A., Moussa, O., Kordzadeh, A., Wilson, M. Lorenzi B., Patil, P., Noaman, Willem, J., Bouras, G., Evans, R., Singh, M., Warrilow, H., Ahmad, A., Tewari, N., Yanni, F., Couch, J., Theophilidou, E., Reilly, J. J., Van Boxel, Gijs, Akbari, K., Zanotti, D., Sgromo, B., Sanders, G., Wheatley, T., Ariyarathenam, A., Reece-Smith, A., Humphreys, L., Choh, C., Carter, N., Knight, B., Pucher, P., Athanasiou, A., Tan, B., Abdulrahman, M., Vickers, J., Akhtar, K., Chaparala, R., Brown, R., Alasmar, M. M.A., Ackroyd, R., Patel, K., Tamhankar, A., Wyman, A., Walker, R., Grace, B., Abbassi, N., Slim, N., Ioannidi, L., Blackshaw, G., Havard, T., Escofet, X., Powell, A., Owera, A., Rashid, F., Jambulingam, P., Padickakudi, J., Ben-Younes, H., McCormack, K., Makey, I. A., Karush, M. K., Seder, C. W., Liptay, M. J., Chmielewski, G., Rosato, E. L., Berger, A. C., Zheng, R., Okolo, E., Singh, A., Scott, C. D., Weyant, M. J., Mitchell, J. D., MS CGO, Cancer, Steering Committee, Committee, Alderson, D., Bundred, J., Rpt, Evans, Gossage, J., Griffiths, E. A., Jefferies, B., Kamarajah, S. K., McKay, S., Mohamed, Nepogodiev, D., Siaw- Acheampong, K., Singh, P., Van Hillegersberg, R., Vohra, R., Wanigasooriya, K., Whitehouse, T., National Leads, Leads, Gjata, A., Moreno, J. I., Takeda, F. R., Kidane, B., Guevara Castro, R., Harustiak, T., Bekele, A., Kechagias, A., Gockel, Kennedy, A., Da Roit, A., Bagajevas, A., Azagra, J. S., Mahendran, H. A., Mejía-Fernández, L., Wijnhoven, B. P.L., El Kafsi, J., Sayyed, R. H., Sousa, M., Sampaio, A. S., Negoi, Blanco, R., Wallner, B., Schneider, P. M., Hsu, P. K., Isik, A., Leads, Site, Gananadha, S., Wills, Devadas, M., Duong, C., Talbot, M., Hii, M. W., Jacobs, R., Andreollo, N. A., Johnston, B., Darling, G., Isaza-Restrepo, A., Rosero, G., Arias-Amézquita, F., Raptis, D., Gaedcke, J., Reim, D., Izbicki, J., Egberts, J. H., Dikinis, S., Kjaer, D. W., Larsen, M. H., Achiam, M. P., Saarnio, J., Theodorou, D., Liakakos, T., Korkolis, D. P., Robb, W. B., Collins, C., Murphy, T., Reynolds, J., Tonini, Migliore, M., Bonavina, L., Valmasoni, M., Bardini, R., Weindelmayer, J., Terashima, M., White, R. E., Alghunaim, E., Elhadi, M., Leon-Takahashi, A. M., Medina-Franco, H., Lau, P. C., Okonta, K. E., Heisterkamp, J., Rosman, C., Beban, G., Babor, R., Gordon, A., Rossaak, J. I., Pal, K. M.I., Qureshi, A. U., Naqi, S. A., Syed, A. A., Barbosa, J., Vicente, C. S., Leite, J., Freire, J., Casaca, R., Costa, R. C.T., Scurtu, R. R., Mogoanta, S. S., Bolca, C., Constantinoiu, S., Sekhniaidze, D., Bjelović, M., So, J. B.Y., Gačevski, G., Loureiro, C., Pera, M., Bianchi, A., Moreno Gijón, M., Martín Fernández, J., Trugeda Carrera, M. S., Vallve-Bernal, M., Cítores Pascual, M. A., Elmahi, S., Halldestam, Hedberg, J., Mönig, S., Gutknecht, S., Tez, M., Guner, A., Tirnaksiz, M. B., Colak, E., Sevinç, B., Hindmarsh, A., Khan, Khoo, D., Byrom, R., Gokhale, J., Wilkerson, P., Jain, P., Chan, D., Robertson, K., Iftikhar, S., Skipworth, R., Forshaw, M., Higgs, S., Nijjar, R., Viswanath, Y. K.S., Turner, P., Dexter, S., Boddy, A., Allum, W. H., Oglesby, S., Cheong, E., Beardsmore, D., Maynard, N., Berrisford, R., Mercer, S., Puig, S., Melhado, R., Kelty, C., Underwood, T., Dawas, K., Lewis, W., Al-Bahrani, A., Bryce, G., Thomas, M., Arndt, A. T., Palazzo, F., Meguid, R. A., Collaborators, Fergusson, J., Beenen, E., Mosse, C., Salim, J., Cheah, S., Wright, T., Cerdeira, M. P., McQuillan, P., Richardson, M., Liem, H., Spillane, J., Yacob, M., Albadawi, F., Thorpe, T., Dingle, A., Cabalag, C., Loi, K., Fisher, O. M., Ward, S., Read, M., Johnson, M., Bassari, R., Bui, H., Cecconello, Raa, Sallum, Da Rocha, J. R.M., Lopes, L. R., Tercioti, V., Jds, Coelho, Ferrer, J. 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Z., Shehzadi, A., Raza, A., Jhanzaib, M. H., Farmanali, J., Zakir, Z., Shakeel, O., Nasir, Khattak, S., Baig, M., Noor, M. A., Ahmed, H. H., Naeem, A., Pinho, A. C., Da Silva, R., Bernardes, A., Campos, J. C., Matos, H., Braga, T., Monteiro, C., Ramos, P., Cabral, F., Gomes, M. P., Martins, P. C., Correia, A. M., Videira, J. F., Ciuce, C., Drasovean, R., Apostu, R., Paitici, S., Racu, A. E., Obleaga, C. V., Beuran, M., Stoica, B., Negoita, Ciubotaru C., Cordos, Birla, R. D., Predescu, D., Hoara, P. A., Tomsa, R., Shneider, Agasiev, M., Ganjara, Gunjić, D., Veselinović, M., Babič, T., Chin, T. S., Shabbir, A., Kim, G., Crnjac, A., Samo, H., Díez Del Val, Del Val, Leturio, S., Ramón, J. M., Dal Cero, M., Rifá, S., Rico, M., Pagan Pomar, A., Martinez Corcoles, J. A., Rodicio Miravalles, J. L., Pais, S. A., Turienzo, S. A., Alvarez, L. S., Campos, P. V., Rendo, A. G., García, S. S., Epg, Santos, Martínez, E. T., Fernández Díaz, M. 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J., Van Boxel, Gijs, Akbari, K., Zanotti, D., Sgromo, B., Sanders, G., Wheatley, T., Ariyarathenam, A., Reece-Smith, A., Humphreys, L., Choh, C., Carter, N., Knight, B., Pucher, P., Athanasiou, A., Tan, B., Abdulrahman, M., Vickers, J., Akhtar, K., Chaparala, R., Brown, R., Alasmar, M. M.A., Ackroyd, R., Patel, K., Tamhankar, A., Wyman, A., Walker, R., Grace, B., Abbassi, N., Slim, N., Ioannidi, L., Blackshaw, G., Havard, T., Escofet, X., Powell, A., Owera, A., Rashid, F., Jambulingam, P., Padickakudi, J., Ben-Younes, H., McCormack, K., Makey, I. A., Karush, M. K., Seder, C. W., Liptay, M. J., Chmielewski, G., Rosato, E. L., Berger, A. C., Zheng, R., Okolo, E., Singh, A., Scott, C. D., Weyant, M. J., and Mitchell, J. D.
- Published
- 2023
21. 89P Immune homeostasis mediators and disease progression in chemotherapy-naïve and neoadjuvant chemotherapy treated gastric cancer patients
- Author
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Kokala-Dimitropoulou, V., Derventzi, A., Tsiatouras, A., Siouta, E., Mitrousias, A., Frountzas, M., Kimpizi, A-D., Toutouzas, K., Theodorou, D., Zografos, G., and Konstadoulakis, M.M.
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- 2023
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22. Intraperitoneal drain placement and outcomes after elective colorectal surgery: International matched, prospective, cohort study
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Sgro A., Blanco-Colino R., Ahmed W. U. R., Brindl N., Gujjuri R. R., Lapolla P., Mills E. C., Perez-Ajates S., Soares A. S., Varghese C., Xu W., McLean K. A., Chapman S. J., Espin-Basany E., Glasbey J. C., Mihaljevic A., Nepogodiev D., Pata F., Pellino G., Pockney P., Dudi-Venkata N. N., Egoroff N., Ludbrook I., Raubenheimer K., Richards T., Delibegovic S., Salibasic M., Amjad T., Dorr-Harim C., Gedeon N., Gsenger J., Tachezy M., Bini S., Gallo G., Gori A., Picciariello A., Podda M., Riboni C., Machatschek M. J., Nguyen A., Jakubauskas M., Kryzauskas M., Poskus T., Kuiper S. Z., Wang J., Wells C. I., Bissett I. P., Augestad K. M., Steinholt I., Vieira B. N., Juloski J., Anabitarte Bautista O., El Kasmy El Kasmy Y., Martin-Borregon P., Ossola Revilla M., Van Straten S., Aktas M. K., Baki B. E., Akhbari M., Baker D., Bhatia S., Brown S., Cambridge W., Kamarajah S. K., Khaw R. A., Kouli O., Murray V., Trout I., Yasin I., Wong J. Y., Reyhani H., Wong K. H. F., Pancharatnam R., Chia W. L., Walmsley A., Hassane A., Saeed D., Wang B., Walters B., Nowinka Z., Alsaif A., Mirza M., Foster K., Luu J., Kakodkar P., Hughes J. T., Yogarajah T., Antypas A., Rahman A., Bradbury M., McLarnon M., Nagi S., Riad A. M., Erotocritou M., Kyriacou H., Kaminskaite V., Alfadhel S., Fatimah Hussain Q., Handa A., Massy-Westropp C., Custovic S., Dimov R., Mughal H., Slavchev M., Ivanov T., Gouvas N., Hegazi A., Kocian P., Kjaer M. D., Mark-Christensen A., Papakonstantinou D., Machairas N., Triantafyllou T., Garoufalia Z., Korkolis D., Castaldi A., Giaccari S., Spolverato G., Pagano G., Milone M., Turri G., Colombo F., Cucinotta E., Poillucci G., Perra T., Tutino R., Belia F., Coletta D., Belli A., Rega D., Cianci P., Pirozzolo G., Di Lena M., Perrone F., Giani A., Lovisetto F., Grassia M., Pipitone Federico N. S., Ferrara F., Biancafarina A., Tamini N., Sinibaldi G., Tuminello F., Galleano R., Sasia D., Bragaglia L., de Manzoni Garberini A., Pesce A., Cassaro F., Venturelli P., Canu G. L., Esposito G., Campanelli M., Cardia R., Ricciardiello M., Sagnotta A., Canonico G., De Marco G., Cappiello A., Pinotti E., Carlei F., Lisi G., Bagaglini G., Farrugia M., Meima-Van Praag E. M., Monteiro C., Pereira M., Botelho P., Quigley A., O'Neill A., Gaule L., Crone L., Arnold A., Grama F., Beuca A., Tulina I., Litvin A., Panyko A., Ossola M. E., Trujillo Diaz J., Marin Santos J. M., Alonso Batanero E., Gortazar de las Casas S., Soldevila Verdeguer C., Colas-Ruiz E., Talal El-Abur I., Garcia Dominguez M., Delorme M., Sauvain M., Ozmen B. B., Ozkan B. B., Calikoglu F., Kural S., Zafer F., Kaya Y., Yalcinkaya A., Kargici K., Tepe M. D., Tatar O. C., Kabadayi E., Yildirim A., Hurmuzlu D., Korkmaz K., Sharma P., Troller R., Hagan N., Mooney J., Light A., Tansey M., Bhojwani D., McGing R. M., Mallon A., Fadel M., Spilsbury C., James R., O'Brien S., Isaac A., Balasubramanya S., Sadik H., Gala T., Chen J. Y., Turner B., Goh E., Hassan K., Karam M., Mason P., Tzoumas N., Noton T., Seehra J. K., Ahmed N., Motiwale R., Tanna V., Argyriou A., Bylapudi S. K., Grace N., Latif S., Hounat A., Kiam J. S., Zaidi M., Elsamani K., Hughes C., Suresh A., Sinan L. O. H., El-Dalil D., Khoo E. J. M., Salim E. E., Stark D., Minhas N., Fowler G., Rees E., Giudiceandrea I., Bardon A., Jayawardena P., Dieseru N., Murphy A., Yates C., Ziolkowska K., Rafie A., Khoda F., Okocha M., Ashdown T., Vitish-Sharma P., Gilliland J., Toh S., Jones K., Devine A., Berry A., McDonnell S., Olivier J., Richardson G., Lim H. J., Slim N., Elsayeh K., Sammour T., Sarpanov A., Belev N., Dimitrov D., Dusek T., Ntomi V., Sotiropoulos G. C., Theodorou D., Nikiteas N., Balalis D., Antropoli C., Altomare D. F., Luglio G., De Palma G. D., Pedrazzani C., Simonelli L., Brozzetti S., Porcu A., Massani M., Grazi G. L., Izzo F., Delrio P., Restini E., Chetta G., Lantone G., Ferrari G., Lucchi A., De Prizio M., Caristo G., Borghi F., Petrucciani N., Huscher C., Cocorullo G., Tonini V., Medas F., Sica G., Cillara N., Anastasi A., Bianco F., Giuliani A., Carlini M., Selvaggi F., Sammarco G., Ozolins A., Malasonoks A., Andrejevic P., Tanis P., van de Ven A., Gerhards M., Ribeiro da Silva B., Silva A., Lima M. J., Kavanagh D., McCawley N., Bintintan V., Karamarkovic A., Sanz Ortega G., De Andres-Asenjo B., Nevado Garcia C., Garcia Florez L. J., Segura-Sampedro J. J., Blas Laina J. L., Ponchietti L., Buchwald P., Gialamas E., Ozben V., Rencuzogullari A., Gecim I. E., Altinel Y., Isik O., Yoldas T., Isik A., Leventoglu S., Erturk M. S., Guner A., Guler S. A., Attaallah W., Ugur M., Ozbalci G. S., Marzook H., Eardley N., Smolarek S., Morgan R., Roxburgh C., Lala A. K., Salama Y., Singh B., Khanna A., Evans M., Shaikh I., Maradi Thippeswamy K., Appleton B., Moug S., Smith I., Smart N., Shah P., Williams G., Khera G., Goede A., Varcada M., Parmar C., Duff S., Hargest R., Marriott P., Speake D., Ben Sassi A., Furfaro B., Daudu D., Golijanin N., Yek W. Y., Capasso G., Mansour L. T., Niu N., Seow W., Hamidovic A., Kulovic E., Letic E., Aljic A., Helez M., Banji-Kelan A., Dimitrova N., Kavradjieva P., Ivanov V., Jukaku A., Hadzhiev D., Gabarski A., Karamanliev M., Vladova P., Iliev S., Yotsov T., Vetsa K., Stavrinidou O., Papatheodorou P., Liassides T., Georgiou T., Al Nassrallah M., Altaf R., Negametzyanov M., Zagibova D., Foltys F., Stefanova H., Paspala A., Bompetsi G., Sidiropoulos T., Stamopoulos P., Triantafyllou A., Theodoropoulos C., Kimpizi A., Palyvou T., Charalabopoulos A., Syllaios A., Schizas D., Liatsou E., Baili E., Vagios I., Tomara N., Davakis S., Palumbo A., Foroni F., Dibra R., Papagni V., Urbani A., Rossin E., Nezi G., Romano P., Amendola A., Esposito E., Manigrasso M., Anoldo P., Vertaldi S., Gecchele G., Sabrina Z. S., Guerci C., Cammarata F., Lamperti G. M. B., Zaffaroni G., Benuzzi L., Ferrario L., Cigognini M., Mazzeo C., Badessi G., Pintabona G., Fassari A., Mingoli A., Cirillo B., D'Alterio C., Brachini G., Tancredi M., Zambon M., Aulicino M., Sapienza P., Liberatore P., Scanu A. M., Feo C. F., Iacomino A., Pelizzo P., Rossi S., Vigna S. A., Grossi U., Grillo V., Agnes A., Schena C. A., Marincola G., Oddi A., Perotti B., Mario V., Perri P., Zazza S., Aversano A., Scala D., Di Lauro K., Leongito M., Piccirillo M., Patrone R., Capuzzolo S., Vignotto C., Bao Q. R., Giuseppe C., Angarano E., Marino F., Pezzolla F., Gigante G., Magistro C., Crippa J., Maspero M., Carnevali P., Trapani R., Zonta S., Agostinelli L., Vittori L., Romeo L., Doria E., Farnesi F., Danna R., Andolfi E., Pellicano' G. A., Angelini M., Scricciolo M., Zanframundo C., Ciulli C., Ripamonti L., Cigagna L., Oldani M., Larcinese A., Rossi D., Picone E., Crescentini G., Marano A., Migliore M., Giuffrida M. C., Palagi S., Testa V., Borrello A., Lucarini A., Garofalo E., Canali G., Orlandi P., Nervegna F., Marchegiani F., Damoli I., Licata A., Trovato C., Alicata F., Sardo F., Milazzo M., Randisi B., Dominici D. M., Sartarelli L., Zanni M., Pisanu A., Soddu C., Delogu D., Erdas E., Campus F., Cappellacci F., Casti F., Marcialis J., Atzeni J., Podda M. G., Sensi B., Franceschilli M., Bellato V., Cannavera A., Putzu G., di Mola F. F., Picardi B., Solinas L., Loponte M., Rossi del Monte S., Di Martino C., Linari C., Spagni G., Capezzuoli L., Tirloni L., Nelli T., Caridi A., Elter C., Camassa M., D'Amico S., Bargellini T., Incollingo P., Montuori M., Maffione F., Romano L., Valiyeva S., Spoletini D., Menegon Tasselli F., Sciaudone G., Selvaggi L., Menna M. P., De Paola G., Fulginiti S., Truskovs A., Weiss C., Saknitis G., Rauscher J. T. R., Larnovskis J., Jeyarajan-Davidsson M., Nitisa D., Gille N., Reiser S. C., Roshan M. H. K., Leseman C., Chen J., van Dalen A. S., Top C., Detering R., Matos C., Silva C., Pinto D., Mendes J., Couto J., Leite M., Velez C., Damasio Cotovio M., Cinza A. M., Pedroso de Lima R., Boyle E., Yang H. W., Banerjee I., Rahmat S., Afzal Z., Reid C., Dumitrascu F., Croyle J. A., Gressmann K., Cullen N., Graham A., Nasehi A., Montano King C., Martin B., Stokell C., Sanderson N., Farnan R., Jassim S., Chan B., Chua Vi Long K., Kaka N., Pandey S., Neo W. X., Chitul A., Bezede C., Cincilei D., David A., Blaga M., Blaga S. N., Fagarasan V., Khetagurova M., Rodimov S., Kapustina A., Mekhralyzade A., Zabiyaka M., Jankovic U., Cuk V., Hajska M., Dubovsky M., Hrosova M., Ferancikova N., Camarero Rodriguez E., Laguna Alcantara F., Adarraga J., Jezieniecki C., Ruiz Soriano M., Gomez Sanz T., Suarez A., Sanchez Garcia C., Cifrian Canales I., Llosa Perez J., Merayo M., Urbieta A., Gegundez Simon A., Tone J. F., Gazo Martinez J., Vicario Bravo M., Chavarrias N., Gil Catalan A., Oseira A., Villalonga B., Jeri S., Perez Calvo J., Nogues A., Cros B., Yanez C., Utrilla Fornals A., Roldon Golet M., Colsa P., Gimenez Maurel T., Axmarker T., Chevallay M., Pham T. V., Sel E. K., Atar C., Aba M., Sarkin M., Akkaya Y. M., Durmaz A. G., Gullu H. F., Boga A., Aktas A., Bakar B., Demirel M. T., Hysejni X., Taser M., Guzel O. R., Bozbiyik O., Ozen D., Olmez M., Uyar B., Gulcek E., Kayacan G. S., Atici N., Gul O. F., Altiner S., Ibis B., Altunsu S., Banaz T., Diler C., Demirbas I., Usta M. A., Erkul O., Orman R., Salih S., Utkan N. Z., Acil C., Ozgur E., Maddahali M., Turhan A. B., Eskici A. B., Ular B., Dogru M., Ozturk O. U., Arslan E. R., Panahi Sharif A., Dikmen E., Ates J., Bircan R., Cavus T., Sever A. E., Balak B., Duman E., Altay L., Emanet O., Cullen F., Tan J. Y., Nathan A., Rottenberg A., Williams C. Y., Mitrofan C. G., Xu D., Bawa J. H., Morris P., Gordon D., Richmond G., Hui J. C., Ighomereho O., Rocks R., McCabe S., Fitzpatrick A., Nicoletti J., Auterson L., Darrah N., Soh V. W. Y., Ong C. S., Utukuri M., Gallagher C., Stuart L. M., Hipolito M., Douglas N., Ghazal R., Parris G., Catchpole J., Bryden M., Jamal S., Karim Z., Lyon-Dean C., Rowley G., Lee K. S., Whitehurst O., Mirza A., Sheikh F., Yousaf H., Bilbao J., Sinclair R., Takar S., Kressel H., Chan V., Schack K., Osborne R., Baldemor S., Smyth S., Gilmour S., Ting A., Bozonelou I., Saunders P., Qhaireel Anwar Q. A., Tirimanna R., Jauhari S., Gardener A., Walker B., Wenban C., Reddy H., Conway-Jones R., Loganathan S., Clynch A., James C., Matey E., Cameron F., Roberts W., Gicquel A., Milliken C., Forbes J., Rubinchik P., Azmi A., Hawkes C., Cornett L., Adarkwah P., McConville R., O'Hara S., Tijare C., Parkes J., Yao L., Ahmad R., Shafiq U., Mhaisalkar A., Gurung A., de Stadler K., Elias S., Thomas T., Madras A., Jani A., Daler H. K., Tong K. S., Sundaralingam S. S., Szal A., Khan A., O'Sullivan C., Baker E., Joseph-Gubral J., Hadley E., Trivedi R., Igwelaezoh E., Barton H., Allison W., Hurst W., Alam F., Parkes I., Jamshaid M., Azizan N., Burgher T., Afzal A., Eltilib I., Zahid M., Sadiq O., Lloyd A., Ho R., Brazukas A., Li C. H., Kamdar M., Mohamed Nazeer M. N., Mighiu A., Kim D., Wilkins L., Kuo L., Rafe T., Maduka D., Cheema H., Farag K., Abdellatif M., Nzewi R., Kruczynska A., Grasselli H., Yousuff M., Bassi R., Mann A. K., Chopra J., Shaikh M., Sa D. S., Tsimplis V., Ghanchi A., Skene E., Asim K., Zaheer M., Chan S., Dalton H., Gibbons K., Adderley O., Chukwujindu I., Jayasuriya I., Sivanu K., Borumand M., Chick G., Bridges I., Tomlin J., McKenna J., Nandra N., Grieco C., Quek F. F., Mercer R., Brankin-Frisby T., Sattar A., Aslam A., Edelsten E., Shafi S., Kouli T., Ford V., Gurung F., Fernandes M., Deader N., Ponniah R., Jamieson S., Davies A., Taubwurcel J., Aung M. T., Desai R., Begum S., Jamadar T., Kangatharan A., Rzeszowski B., Ho C., Yap S. H. K., Prendergast M., Sethi R., Duku A., Lowe C., Bray J., Ghobrial M., Nichita V., Wagstaff A., Rengasamy E., Abu Hassan F., Mahmood H., Savill N., Shah S., Almeida T., Edwards A., Catchpole B., Halford Z., Carmichael A., Alsusa H., Boyd M., Williams J., Feyi-Waboso J., Patel M., Zeidan Z., Bailey E., Bapty J., Brazkiewicz M., Tremlett A., Pringle H., Mankal S., Chung W., Parry-Jones E., Anderson K., McForrester A., Stanley A., Hoather A., Wise H., Laid I., Scriven J., Braniste A., Wilson A., Le Blevec L., Pakunwanich N., Evans N., Chong H. L., White C., Hunter J., Haque M., Vanalia P., Murdoch S., Choudhary T., McCann A., Harun A., Shah H., Hunt S., Shafiq Y., Bickley-Morris E., Emms L., Dare M., Akula Y., Deliyannis E., Mayes F., Ellacott M., Zagorac Z., Farren A., Manning C., Hughed C., Stewart E. G., Lim K. 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Walter L., Dhillon S., Rao S., Anthony A., Ashaye A., Phillips N., Faderani R., Pengelly S., Choi S., Kwak S.Y., Lau Y.H.L., Bagheri K., Ong D.Y.C., Kerr E., Falconer K., Clancy N., Douglas S., Zhang Y., Greenfield F., Mutanga I., McAlinden J., Willis L., Adefolaju A., Agarwal H., Barter R., Harris G., Spencer G., Lee M.W., Vadiveloo V.T., Herbert G., Patel R., Shah M., El Falaha S., Wong C., Soare C., Akram J., Bozhkova L., Ma Y., Vo U.G., Tan H.W.N., Leto L., Kamal M.A., Hadzhieva E., Krastev P., Tonchev P., Kokkinos G., Pozotou I., Sabbagh D., Votava J., St F., Koliakos N., Tsaparas P., Zografos G., Mantas D., Tsourouflis G., Fradelos E., Trigiante G., Labellarte G., Resta G., Capelli G., D'Amore A., Verlingieri V., Campagnaro T., Maffioli A., Viscosi F., De Lucia C., Meneghini S., Fancellu A., Colella M., Biondi A., De Peppo V., Pace U., Albino V., Gattulli D., Piangerelli A., Kalivaci D., Sisto G., Mazzola M., Caneparo A., Lunghi E.G., Nespoli L.C., Angrisani M., Langone A., 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L., White, C., Hunter, J., Haque, M., Vanalia, P., Murdoch, S., Choudhary, T., Mccann, A., Harun, A., Shah, H., Hunt, S., Shafiq, Y., Bickley-Morris, E., Emms, L., Dare, M., Akula, Y., Deliyannis, E., Mayes, F., Ellacott, M., Zagorac, Z., Farren, A., Manning, C., Hughed, C., Stewart, E. G., Lim, K. H., Chohan, N., Thaker, A., Thompson, B., Ahari, D., Burdekin, E., Okwu, U., Akintunde, A., Lhaf, F., Douthwaite, J., Govindan, R., Leelamanthep, S., Gull, E., Wright, F., Dundas, L., Mackdermott, N., Burchi-Khairy, T., Campbell, I., Walsh, J., Yeo, J. Y., Meehan, S., Banerjee, D., Fu, M., Kawka, M., Ali, T., Hussain, Z., Thomas, C., Ahmad, H., Moroney, J., Yick, C., Risquet, R., Ntuiabane, D., Shimato, M., Khan, M., Ilangovan, S., Vaselli, N. 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A., Kurtenkov, M., Jovanovic, M., Vician, M., Egea Arias, P., Beltran de Heredia, J., Labalde Martinez, M., De Santiago Alvarez, I., Alvarez-Gallego, M., Rodriguez Artigas, J. M., Dwidar, O., Korkmaz, H. K., Eray, I. C., Meric, S., Aydin, R., Cetin, B., Karaca, B. E., Kuyumcu, O. F., Yuksel, E., Uprak, T. K., Karabulut, K., Kavukcu, E., Mansor, A., Hackett, R., Zammit-Maempel, M., Sabaratnam, R., Maan, A., Ferarrio, I., Dixon, L., Halai, H., Sethi, S., Nelson, L., Grassam-Rowe, A., Krishnan, E., Deeny, D., Mckeever, M., George Pandeth, A., Dhavala, P., Sreenivasan, S., Sundaram Venkatesan, G., Zhu, L., Atiyah, Z., Gregory, J., Morey, T., Seymour, Z., Holdsworth, L., Abdelmahmoud, S., Bourhill, J., Bisheet, G., Shaw, J., Kulkarni, K., Kumarakulasingam, P., Pillay, S., Al-Habsi, R., Kungwengwe, G., Richards, J., Davoudi, K., Ibrahim, B., Tailor, B., Zayed, M., Chen, F., Bailey, S., Sheefat, S., Nawaz, G., Pawar, R., Marsh, S., Sam, Z. H., Roy Bentley, S., Simpson, C., Hughes, J., Lim, Y., Ooi, R., Toh, W. H., Mannion, P., Lovett, A., Kincius, A., Hussein, S., Kirby, E., Beckett, R. G., Salmon, J., Glynn, T., Choo, S. Y., Lyons, S., Browne, D., Ravindran, W., Ahmad, S., Zhu, X., Mcnulty, J., Mccarthy, L., Ng, J., Karmally, Z., Mcteir, K., Hanna, M., Tan, E., Namdeo, S., Schembri, R., and Pusey, E.
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Adult ,Elective Surgical Procedure ,Aged ,Cohort Studies ,Drainage ,Elective Surgical Procedures ,Female ,Humans ,Postoperative Complications ,Prospective Studies ,Surgical Wound Infection ,Colorectal Surgery ,drain ,intrabdominal ,Adult, Aged, Cohort Studies, Colorectal Surgery, Drainage, Elective Surgical Procedures, Female, Humans, Postoperative Complications, Prospective Studies, Surgical Wound Infection ,Settore MED/18 ,Settore MED/18 - Chirurgia Generale ,Prospective Studie ,Surgery ,Postoperative Complication ,Cohort Studie ,drain, intrabdominal ,Human - Abstract
Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien–Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P < 0.001) and an increased risk of SSIs (OR 2.47, 1.50 to 4.05; P < 0.001). Conclusion Intraperitoneal drain placement after elective colorectal surgery is not associated with earlier detection of postoperative collections, but prolongs hospital stay and increases SSI risk.
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- 2022
23. The use of measurement uncertainty and precision data in conformity assessment of automotive fuel products
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Theodorou, D. and Zannikos, F.
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- 2014
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24. Postoperative outcomes in oesophagectomy with trainee involvement
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R P, T Evans, K Kamarajah, S, Bundred, J, Nepogodiev, D, Hodson, J, R van Hillegersberg, Gossage, J, Vohra, R, A Griffiths, E, Singh, P, Alderson, D, Jefferies, B, Mckay, S, Mohamed, I, K Siaw- Acheampong, Wanigasooriya, K, Whitehouse, T, Gjata, A, I Moreno, J, R Takeda, F, Kidane, B, R Guevara Castro, Harustiak, T, Bekele, A, Kechagias, A, Gockel, I, Kennedy, A, A Da Roit, Bagajevas, A, S Azagra, J, A Mahendran, H, Mej??a-Fern??ndez, L, B P, L Wijnhoven, J El Kafsi, H Sayyed, R, Sousa, M, S Sampaio, A, Negoi, I, Blanco, R, Wallner, B, M Schneider, P, K Hsu, P, Isik, A, Gananadha, S, Wills, V, Devadas, M, Duong, C, Talbot, M, W Hii, M, Jacobs, R, A Andreollo, N, Johnston, B, Darling, G, Isaza-Restrepo, A, Rosero, G, Arias-Am??zquita, F, Raptis, D, Gaedcke, J, Reim, D, Izbicki, J, H Egberts, J, Dikinis, S, W Kjaer, D, H Larsen, M, P Achiam, M, Saarnio, J, Theodorou, D, Liakakos, T, P Korkolis, D, B Robb, W, Collins, C, Murphy, T, Reynolds, J, Tonini, V, Migliore, M, Bonavina, L, Valmasoni, M, Bardini, R, Weindelmayer, J, Terashima, M, E White, R, Alghunaim, E, Elhadi, M, M Leon-Takahashi, A, Medina-Franco, H, C Lau, P, E Okonta, K, Heisterkamp, J, Rosman, C, Beban, G, Babor, R, Gordon, A, I Rossaak, J, K M, I Pal, U Qureshi, A, A Naqi, S, A Syed, A, Barbosa, J, S Vicente, C, Leite, J, Freire, J, Casaca, R, R C, T Costa, R Scurtu, R, S Mogoanta, S, Bolca, C, Constantinoiu, S, Sekhniaidze, D, Bjelovi??, M, J B, Y So, Ga??evski, G, Loureiro, C, Pera, M, Bianchi, A, M Moreno Gij??n, J Mart??n Fern??ndez, S Trugeda Carrera, M, Vallve-Bernal, M, A C??tores Pascual, M, Elmahi, S, Hedberg, J, M??nig, S, Gutknecht, S, Tez, M, Guner, A, B Tirnaksiz, T, Colak, E, Sevin??, B, Hindmarsh, A, Khan, I, Khoo, D, Byrom, R, Gokhale, J, Wilkerson, P, Jain, P, Chan, D, Robertson, K, Iftikhar, S, Skipworth, R, Forshaw, M, Higgs, S, Nijjar, R, Y K, S Viswanath, Turner, P, Dexter, S, Boddy, A, H Allum, W, Oglesby, S, Cheong, E, Beardsmore, D, Maynard, N, Berrisford, R, Mercer, S, Puig, S, Melhado, R, Kelty, C, Underwood, T, Dawas, K, Lewis, W, Al-Bahrani, A, Bryce, G, Thomas, M, T Arndt, A, Palazzo, F, A Meguid, R, Fergusson, J, Beenen, E, Mosse, C, Salim, J, Cheah, S, Wright, T, P Cerdeira, M, Mcquillan, P, Richardson, M, Liem, H, Spillane, J, Yacob, M, Albadawi, F, Thorpe, T, Dingle, A, Cabalag, C, Loi, K, M Fisher, O, Ward, S, Read, M, Johnson, M, Bassari, R, Bui, H, Cecconello, I, R A, A Sallum, J R, M da Rocha, R Lopes, L, Tercioti, V, J D, S Coelho, J A, P Ferrer, Buduhan, G, Tan, L, Srinathan, S, Shea, P, Yeung, J, Allison, F, Carroll, P, Vargas-Barato, F, Gonzalez, F, Ortega, J, Nino-Torres, L, C Beltr??n-Garc??a, T, Castilla, L, Pineda, M, Bastidas, A, G??mez-Mayorga, J, Cort??s, N, Cetares, C, Caceres, S, Duarte, S, Pazdro, A, Snajdauf, M, Faltova, H, Sevcikova, M, B Mortensen, P, Katballe, N, Ingemann, T, Morten, B, Kruhlikava, I, P Ainswort, A, M Stilling, N, Eckardt, J, Holm, J, Thorsteinsson, M, Siemsen, M, Brandt, B, Nega, B, Teferra, E, Tizazu, A, S Kauppila, J, Koivukangas, V, Meril??inen, S, Gruetzmann, R, Krautz, C, Weber, G, Golcher, H, Emons, G, Azizian, A, Ebeling, M, Niebisch, S, Kreuser, N, Albanese, G, Hesse, J, Volovnik, L, Boecher, U, Reeh, M, Triantafyllou, S, Schizas, D, Michalinos, A, Baili, E, Mpoura, M, Charalabopoulos, A, K Manatakis, D, Balalis, D, Bolger, J, Baban, C, Mastrosimone, A, Mcanena, O, Quinn, A, B ?? 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White, RE, Alghunaim, E, Elhadi, M, Leon-Takahashi, AM, Medina-Franco, H, Lau, PC, Okonta, KE, Heisterkamp, J, Rosman, C, Beban, G, Babor, R, Gordon, A, Rossaak, JI, Pal, KMI, Qureshi, AU, Naqi, SA, Syed, AA, Barbosa, J, Vicente, CS, Leite, J, Freire, J, Casaca, R, Costa, RCT, Scurtu, RR, Mogoanta, SS, Bolca, C, Constantinoiu, S, Sekhniaidze, D, So, JBY, Gacvski, G, Loureiro, C, Pera, M, Bianchi, A, Gijon, MM, Fernandez, JM, Carrera, MST, Vallve-Bernal, M, Pascual, MAC, Elmahi, S, Halldestam, I, Hedberg, J, Monig, S, Gutknecht, S, Tez, M, Guner, A, Tirnaksiz, TB, Colak, E, Sevinc, B, Hindmarsh, A, Khan, I, Khoo, D, Byrom, R, Gokhale, J, Wilkerson, P, Jain, P, Chan, D, Robertson, K, Iftikhar, S, Skipworth, R, Forshaw, M, Higgs, S, Nijjar, R, Viswanath, YKS, Turner, P, Dexter, S, Boddy, A, Allum, WH, Oglesby, S, Cheong, E, Beardsmore, D, Maynard, N, Berrisford, R, Mercer, S, Puig, S, Melhado, R, Kelty, C, Underwood, T, Dawas, K, Lewis, W, Al-Bahrani, A, Bryce, G, Thomas, M, Arndt, AT, Palazzo, F, Meguid, RA, Fergusson, J, Beenen, E, Mosse, C, Salim, J, Cheah, S, Wright, T, Cerdeira, MP, McQuillan, P, Richardson, M, Liem, H, Spillane, J, Yacob, M, Albadawi, F, Thorpe, T, Dingle, A, Cabalag, C, Loi, K, Fisher, OM, Ward, S, Read, M, Johnson, M, Bassari, R, Bui, H, Cecconello, I, Sallum, RAA, da Rocha, JRM, Lopes, LR, Tercioti, V, Coelho, JDS, Ferrer, JAP, Buduhan, G, Tan, L, Srinathan, S, Shea, P, Yeung, J, Allison, F, Carroll, P, Vargas-Barato, F, Gonzalez, F, Ortega, J, Nino-Torres, L, Beltran-Garcia, TC, Castilla, L, Pineda, M, Bastidas, A, Gomez-Mayorga, J, Cortes, N, Cetares, C, Caceres, S, Duarte, S, Pazdro, A, Snajdauf, M, Faltova, H, Sevcikova, M, Mortensen, PB, Katballe, N, Ingemann, T, Morten, B, Kruhlikava, I, Ainswort, AP, Stilling, NM, Eckardt, J, Holm, J, Thorsteinsson, M, Siemsen, M, Brandt, B, Nega, B, Teferra, E, Tizazu, A, Kauppila, JS, Koivukangas, V, Merilainen, S, Gruetzmann, R, Krautz, C, Weber, G, Golcher, H, Emons, G, Azizian, A, Ebeling, M, Niebisch, S, Kreuser, N, Albanese, G, Hesse, J, Volovnik, L, Boecher, U, Reeh, M, Triantafyllou, S, Schizas, D, Michalinos, A, Baili, E, Mpoura, M, Charalabopoulos, A, Manatakis, DK, Balalis, D, Bolger, J, Baban, C, Mastrosimone, A, McAnena, O, Quinn, A, Suilleabhain, CBO, Hennessy, MM, Ivanovski, I, Khizer, H, Ravi, N, Donlon, N, Cervellera, M, Vaccari, S, Bianchini, S, Sartarelli, L, Asti, E, Bernardi, D, Merigliano, S, Provenzano, L, Scarpa, M, Saadeh, L, Salmaso, B, De Manzoni, G, Giacopuzzi, S, La Mendola, R, De Pasqual, CA, Tsubosa, Y, Niihara, M, Irino, T, Makuuchi, R, Ishii, K, Mwachiro, M, Fekadu, A, Odera, A, Mwachiro, E, AlShehab, D, Ahmed, HA, Shebani, AO, Elhadi, A, Elnagar, FA, Elnagar, HF, Makkai-Popa, ST, Wong, LF, Yunrong, T, Thanninalai, S, Aik, HC, Soon, PW, Huei, TJ, Basave, HNL, Cortes-Gonzalez, R, Lagarde, SM, van Lanschot, JJB, Cords, C, Jansen, WA, Martijnse, I, Matthijsen, R, Bouwense, S, Klarenbeek, B, Verstegen, M, van Workum, F, Ruurda, JP, van der Veen, A, van den Berg, JW, Evenett, N, Johnston, P, Patel, R, MacCormick, A, Young, M, Smith, B, Ekwunife, C, Memon, AH, Shaikh, K, Wajid, A, Khalil, N, Haris, M, Mirza, ZU, Qudus, SBA, Sarwar, MZ, Shehzadi, A, Raza, A, Jhanzaib, MH, Farmanali, J, Zakir, Z, Shakeel, O, Nasir, I, Khattak, S, Baig, M, Noor, MA, Ahmed, HH, Naeem, A, Pinho, AC, da Silva, R, Bernardes, A, Campos, JC, Matos, H, Braga, T, Monteiro, C, Ramos, P, Cabral, F, Gomes, MP, Martins, PC, Correia, AM, Videira, JF, Ciuce, C, Drasovean, R, Apostu, R, Paitici, S, Racu, AE, Obleaga, CV, Beuran, M, Stoica, B, Ciubotaru, C, Negoita, V, Cordos, I, Birla, RD, Predescu, D, Hoara, PA, Tomsa, R, Shneider, V, Agasiev, M, Ganjara, I, Gunjic, D, Veselinovic, M, Babic, T, Chin, TS, Shabbir, A, Kim, G, Crnjac, A, Samo, H, del Val, ID, Leturio, S, Ramon, JM, Dal Cero, M, Rifa, S, Rico, M, Pomar, AP, Corcoles, JAM, Miravalles, JLR, Pais, SA, Turienzo, SA, Alvarez, LS, Campos, PV, Rendo, AG, Garcia, SS, Santos, EPG, Martinez, ET, Diaz, MJF, Alvarez, CM, Martin, VC, Lopez, CD, Rodrigo, AR, Sanchez, LEP, Cuadrado, MB, Carrasco, CT, Bhojwani, EC, Sanchez, DP, Ahmed, ME, Dzhendov, T, Lindberg, F, Rutegard, M, Sundbom, M, Mickael, C, Colucci, N, Schnider, A, Er, S, Kurnaz, E, Turkyilmaz, S, Turkyilmaz, A, Yildirim, R, Baki, BE, Akkapulu, N, Karahan, O, Damburaci, N, Hardwick, R, Safranek, P, Sujendran, V, Bennett, J, Afzal, Z, Shrotri, M, Chan, B, Exarchou, K, Gilbert, T, Amalesh, T, Mukherjee, D, Mukherjee, S, Wiggins, TH, Kennedy, R, McCain, S, Harris, A, Dobson, G, Davies, N, Wilson, I, Mayo, D, Bennett, D, Young, R, Manby, P, Blencowe, N, Schiller, M, Byrne, B, Mitton, D, Wong, V, Elshaer, A, Cowen, M, Menon, V, Tan, LC, McLaughlin, E, Koshy, R, Sharp, C, Brewer, H, Das, N, Cox, M, Al Khyatt, W, Worku, D, Iqbal, R, Walls, L, McGregor, R, Fullarton, G, Macdonald, A, MacKay, C, Craig, C, Dwerryhouse, S, Hornby, S, Jaunoo, S, Wadley, M, Baker, C, Saad, M, Kelly, M, Davies, A, Di Maggio, F, Mistry, P, Singhal, R, Tucker, O, Kapoulas, S, Powell-Brett, S, Davis, P, Bromley, G, Watson, L, Verma, R, Ward, J, Shetty, V, Ball, C, Pursnani, K, Sarela, A, Ling, HS, Mehta, S, Hayden, J, To, N, Palser, T, Hunter, D, Supramaniam, K, Butt, Z, Ahmed, A, Kumar, S, Chaudry, A, Moussa, O, Kordzadeh, A, Patil, P, Noaman, I, Willem, J, Bouras, G, Evans, R, Singh, M, Warrilow, H, Ahmad, A, Tewari, N, Yanni, F, Couch, J, Theophilidou, E, Reilly, JJ, van Boxel, G, Akbari, K, Zanotti, D, Sgromo, B, Sanders, G, Wheatley, T, Ariyarathenam, A, Reece-Smith, A, Humphreys, L, Choh, C, Carter, N, Knight, B, Pucher, P, Athanasiou, A, Tan, B, Abdulrahman, M, Vickers, J, Akhtar, K, Chaparala, R, Brown, R, Alasmar, MMA, Ackroyd, R, Patel, K, Tamhankar, A, Wyman, A, Walker, R, Grace, B, Abbassi, N, Slim, N, Ioannidi, L, Blackshaw, G, Havard, T, Escofet, X, Powell, A, Owera, A, Rashid, F, Jambulingam, P, Padickakudi, J, Ben-Younes, H, McCormack, K, Makey, IA, Karush, MK, Seder, CW, Liptay, MJ, Chmielewski, G, Rosato, EL, Berger, AC, Zheng, R, Okolo, E, Singh, A, Scott, CD, Weyant, MJ, and Mitchell, JD
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squamous cell carcinoma ,surgical mortality ,AcademicSubjects/MED00910 ,Esophageal Neoplasms ,SURGERY ,IMPACT ,clinical outcome ,Anastomotic Leak ,Adult ,aged ,anastomosis leakage ,article ,cancer staging ,cardiovascular disease assessment ,Charlson Comorbidity Index ,cohort analysis ,ECOG Performance Status ,esophagectomy ,esophagus cancer ,female ,follow up ,histology ,human ,intensive care unit ,length of stay ,major clinical study ,male ,middle aged ,mortality ,necrosis ,neoadjuvant chemoradiotherapy ,neoadjuvant chemotherapy ,observational study ,postoperative complication ,postoperative period ,reoperation ,surgical technique ,Cohort Studies ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,Surgical ,Anastomosis, Surgical ,General Medicine ,Original Article ,AcademicSubjects/MED00010 ,Life Sciences & Biomedicine ,Anastomosis ,SOCIETY ,Bjs/5 ,trainee ,oesophagectomy, trainee ,Humans ,Esophagectomy ,All institutes and research themes of the Radboud University Medical Center ,SDG 3 - Good Health and Well-being ,RESIDENT INVOLVEMENT ,Science & Technology ,SURGICAL OUTCOMES - Abstract
Background The complexity of oesophageal surgery and the significant risk of morbidity necessitates that oesophagectomy is predominantly performed by a consultant surgeon, or a senior trainee under their supervision. The aim of this study was to determine the impact of trainee involvement in oesophagectomy on postoperative outcomes in an international multicentre setting. Methods Data from the multicentre Oesophago-Gastric Anastomosis Study Group (OGAA) cohort study were analysed, which comprised prospectively collected data from patients undergoing oesophagectomy for oesophageal cancer between April 2018 and December 2018. Procedures were grouped by the level of trainee involvement, and univariable and multivariable analyses were performed to compare patient outcomes across groups. Results Of 2232 oesophagectomies from 137 centres in 41 countries, trainees were involved in 29.1 per cent of them (n = 650), performing only the abdominal phase in 230, only the chest and/or neck phases in 130, and all phases in 315 procedures. For procedures with a chest anastomosis, those with trainee involvement had similar 90-day mortality, complication and reoperation rates to consultant-performed oesophagectomies (P = 0.451, P = 0.318, and P = 0.382, respectively), while anastomotic leak rates were significantly lower in the trainee groups (P = 0.030). Procedures with a neck anastomosis had equivalent complication, anastomotic leak, and reoperation rates (P = 0.150, P = 0.430, and P = 0.632, respectively) in trainee-involved versus consultant-performed oesophagectomies, with significantly lower 90-day mortality in the trainee groups (P = 0.005). Conclusion Trainee involvement was not found to be associated with significantly inferior postoperative outcomes for selected patients undergoing oesophagectomy. The results support continued supervised trainee involvement in oesophageal cancer surgery., The aim of this study was to determine the impact of trainee involvement in oesophagectomy on perioperative outcomes in the international multicentre Oesophago-Gastric Anastomosis Audit (OGAA). Analysis of 2232 oesophagectomies has shown that trainee involvement did not negatively impact perioperative outcomes.
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- 2022
25. Polymers at Surfaces and Interfaces
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Theodorou, D. N., Dünweg, Burkhard, editor, Landau, David P., editor, and Milchev, Andrey I., editor
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- 2003
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26. Anastomotic leak following oesophagectomy: research priorities from an international Delphi consensus study
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Kamarajah, Sivesh K, Mohamed, Imran, Nepogodiev, Dmitri, Evans, Richard PT, Hodson, James, Griffiths, Ewen A, Singh, Pritam, Committee, Steering, Alderson, Derek, Bundred, James, Evans, Richard, Gossage, James, Jefferies, Benjamin, Mckay, Siobhan, Siaw-Acheampong, Kobby, van Hillegersberg, Richard, Vohra, Ravinder, Wanigsooriya, Kasun, Whitehouse, Tony, Bekele, A, Achiam, Mp, Ahmed, H, Ainsworth, A, Akhtar, K, Akkapulu, N, Al-Khyatt, W, Alasmar, M, Alemu, Bn, Alfieri, R, Alkhaffaf, B, Alvarez, Ls, Amahu, V, Andreollo, Na, Arias, F, Ariyarathenam, A, Arndt, A, Athanasiou, A, Azagra, Js, Baban, C, Babor, R, Baili, E, Balla, A, Beenen, E, Bendixen, M, Bennett, J, Bergeat, D, Bernardes, Aj, Bernardi, D, Berrisford, R, Bianchi, A, Bjelovic, M, Blencowe, N, Boddy, A, Bogdan, S, Bolger, J, Bonavina, L, Bouras, G, Bouwense, S, Bowrey, D, Bragg, D, Bright, Tn, Broderick, S, Buduhan, G, Byrne, B, Carey, D, Carroll, P, Carrott, P, Casaca, R, Castro, Rg, Catton, J, Cerdeira, Mp, Chang, Ac, Charalabopoulos, A, Chaudry, A, Choh, C, Ciprian, B, Ciubotaru, C, Coe, P, Colak, E, Colino, Rb, Colucci, N, Costa, Pm, Daniela, K, Das, N, Davies, A, Davies, N, de Manzoni, G, del Val, Id, Dexter, S, Dolan, J, Donlon, N, Donohoe, C, Duffy, J, Dwerryhouse, S, Egberts, Jh, Ekwunife, C, Elhadi, A, Elhadi, M, Elliott, Ja, Elnagar, H, Elnagar, F, Faraj, Ha, Farooq, N, Fearon, N, Fekaj, E, Forshaw, M, Freire, J, Gacevski, G, Gaedcke, J, Giacopuzzi, S, Gijón, Mm, Gisbertz, S, Golcher, H, Gordon, A, Gossage, J, Griffiths, E, Grimminger, P, Guner, A, Gutknecht, S, Harustiak, T, Hedberg, J, Heisterkamp, J, Hii, M, Hindmarsh, A, Holm, J, Hornby, S, Isik, A, Izbicki, J, Jagadesham, V, Jaunoo, S, Johansson, J, Johnson, Ma, Johnston, B, Kapoulas, S, Kauppi, J, Kauppila, Jh, Kechagias, A, Kelly, M, Kelty, C, Kennedy, A, Khan, M, Khattak, S, Kidane, B, Kjaer, Dw, Klarenbeek, B, Korkolis, Dp, Koshy, Rm, Krantz, S, Lagarde, S, Larsen, Mh, Lau, Pc, Leeder, Pc, Leite, Js, Liakakos, T, Madhavan, A, Mahdi, Si, Mahendran, Ha, Mahmoodzadeh, H, Majbar, A, Manatakis, D, Markar, S, Martijnse, I, Matei, B, Matos da Costa, P, Mccormack, K, Mcnally, S, Meriläinen, S, Merrett, N, Migliore, M, Mingol, F, Mitton, D, Mogoanta, Ss, Mönig, Sp, Moorthy, K, Muhinga, M, Mwachiro, M, Naeem, A, Nasir, I, Navidi, M, Negoi, I, Negoiţă, V, Niazi, Sk, Nilsson, M, Pazdro, A, Pera, M, Perez, Cj, Perivoliotis, K, Peters, C, Phillips, Aw, Powell, A, Prove, L, Pucher, Ph, Rahman, S, Räsänen, Jv, Read, M, Reeh, M, Reim, D, Reynolds, J, Robb, Wb, Robertson, K, Rodica, B, Rosero, G, Rosman, C, Saadeh, L, Santos, Eg, Saunders, J, Sayyed, R, Schizas, D, Scurtu, Rr, Sekhniaidze, D, Serralheiro, Pa, Sevinç, B, Sgromo, B, Shakeel, O, Siemsen, M, Skipworth, R, Smith, B, Soares, A, Spillane, J, Steliga, Ma, Sundbom, M, Sydiuk, A, Takahashi, Aml, Talbot, M, Tan, B, Tareen, Ma, Tewari, N, Tez, M, Theodorou, D, Tita, A, Toledo, E, Townend, Pj, Triantafyllou, T, Trugeda, M, Tucker, O, Turner, P, Turrado, V, Underwood, T, Vaccari, S, Valmasoni, M, van Berge Henegouwen, M, van Boxel, G, van den Berg, Jw, van der Sluis, P, van Hillegersberg, R, van Lanschot, Jjb, van Workum, F, Vickers, J, Videira, J, Viswanath, Y, Vohra, R, Voon, K, Wadley, M, Walker, R, Wallner, B, Walsh, Tn, Weindelmayer, J, Welch, N, Wheatley, T, Wijnhoven, B, Wong, Lf, Yanni, F, Yeung, J, Zacharakis, Null, and Moenig, Stefan Paul
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medicine.medical_specialty ,Leak ,Biomedical Research ,Delphi Technique ,Steering committee ,medicine.medical_treatment ,Delphi method ,Anastomotic Leak ,030230 surgery ,Esophagectomy ,Evidence-Based Medicine ,Humans ,Surveys and Questionnaires ,Research ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,03 medical and health sciences ,0302 clinical medicine ,medicine ,computer.programming_language ,ddc:617 ,business.industry ,General surgery ,030220 oncology & carcinogenesis ,Surgery ,business ,computer ,Delphi - Abstract
Background The Oesophago-Gastric Anastomosis Audit (OGAA) is an international collaborative group set up to study anastomotic leak outcomes after oesophagectomy for cancer. This Delphi study aimed to prioritize future research areas of unmet clinical need in RCTs to reduce anastomotic leaks. Methods A modified Delphi process was overseen by the OGAA committee, national leads, and engaged clinicians from high-income countries (HICs) and low/middle-income countries (LMICs). A three-stage iterative process was used to prioritize research topics, including a scoping systematic review (stage 1), and two rounds of anonymous electronic voting (stages 2 and 3) addressing research priority and ability to recruit. Stratified analyses were performed by country income. Results In stage 1, the steering committee proposed research topics across six domains: preoperative optimization, surgical oncology, technical approach, anastomotic technique, enhanced recovery and nutrition, and management of leaks. In stages 2 and stage 3, 192 and 171 respondents respectively participated in online voting. Prioritized research topics include prehabilitation, anastomotic technique, and timing of surgery after neoadjuvant chemo(radio)therapy. Stratified analyses by country income demonstrated no significant differences in research priorities between HICs and LMICs. However, for ability to recruit, there were significant differences between LMICs and HICs for themes related to the technical approach (minimally invasive, width of gastric tube, ischaemic preconditioning) and location of the anastomosis. Conclusion Several areas of research priority are consistent across LMICs and HICs, but discrepancies in ability to recruit by country income will inform future study design.
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- 2020
27. Is there room for improvement in oesophageal cancer surgery? Results of a prospective protocol for individualization of surgical treatment
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Doulami, G., Triantafyllou, S., Memos, N., Kokoroskos, N., Hasemaki, N., Katsaragakis, S., Zografos, G., and Theodorou, D.
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- 2015
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28. Textbook outcome following oesophagectomy for cancer: international cohort study
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Kamarajah, S. K., Evans, R. P. T., Nepogodiev, D., Hodson, J., Bundred, J. R., Gockel, I., Gossage, J. A., Isik, A., Kidane, B., Mahendran, H. A., Negoi, I., Okonta, K. E., Sayyed, R., van Hillegersberg, R., Vohra, R. S., Wijnhoven, B. P. L., Singh, P., Griffiths, E. A., Alderson, D., Bundred, J., Gossage, J., Jefferies, B., Mckay, S., Mohamed, I., Siaw-Acheampong, K., Vohra, R., Wanigasooriya, K., Whitehouse, T., Gjata, A., Moreno, J. I., Takeda, F. R., Guevara Castro, R., Harustiak, T., Bekele, A., Kechagias, A., Kennedy, A., Da Roit, A., Bagajevas, A., Azagra, J. S., Mej??a-Fern??ndez, L., El Kafsi, J., Sayyed, R. H., Sousa M, M., Sampaio, A. S., Blanco, R., Wallner, B., Schneider, P. M., Hsu, P. K., Gananadha, S., Wills, V., Devadas, M., Duong, C., Talbot, M., Hii, M. W., Jacobs, R., Andreollo, N. A., Johnston, B., Darling, G., Isaza-Restrepo, A., Rosero, G., Arias-Am??zquita, F., Raptis, D., Gaedcke, J., Reim, D., Izbicki, J., Egberts, J. H., Dikinis, S., Kjaer, D. W., Larsen, M. H., Achiam, M. P., Saarnio, J., Theodorou, D., Liakakos, T., Korkolis, D. P., Robb, W. B., Collins, C., Murphy, T., Reynolds, J., Tonini, V., Migliore, M., Bonavina, L., Valmasoni, M., Bardini, R., Weindelmayer, J., Terashima, M., White, R. E., Alghunaim, E., Elhadi, M., Leon-Takahashi, A. M., Medina-Franco, H., Lau, P. C., Heisterkamp, J., Rosman, C., Beban, G., Babor, R., Gordon, A., Rossaak, J. I., Pal, K. M. I., Qureshi, A. U., Naqi, S. A., Syed, A. A., Barbosa, J., Vicente, C. S., Leite, J., Freire, J., Casaca, R., Costa, R. C. T., Scurtu, R. R., Mogoanta, S. S., Bolca, C., Constantinoiu, S., Sekhniaidze, D., Bjelovi??, M., J. B. Y., So, Ga??evski, G., Loureiro, C., Pera, M., Bianchi, A., Moreno Gij??n, M., Fern??ndez, J. Mart??n., Trugeda Carrera, M. S., Vallve-Bernal, M., C??tores Pascual, M. A., Elmahi, S., Halldestam, I., Hedberg, J., M??nig, S., Gutknecht, S., Tez, M., Guner, A., Tirnaksiz, M. B., Colak, E., Sevin??, B., Hindmarsh, A., Khan, I., Khoo, D., Byrom, R., Gokhale, J., Wilkerson, P., Jain, P., Chan, D., Robertson, K., Iftikhar, S., Skipworth, R., Forshaw, M., Higgs, S., Nijjar, R., Viswanath, Y. K. S., Turner, P., Dexter, S., Boddy, A., Allum, W. H., Oglesby, S., Cheong, E., Beardsmore, D., Maynard, N., Berrisford, R., Mercer, S., Puig, S., Melhado, R., Kelty, C., Underwood, T., Dawas, K., Lewis, W., Bryce, G., Thomas, M., Arndt, A. T., Palazzo, F., Meguid, R. A., Fergusson, J., Beenen, E., Mosse, C., Salim, J., Cheah, S., Wright, T., Cerdeira, M. P., Mcquillan, P., Richardson, M., Liem, H., Spillane, J., Yacob, M., Albadawi, F., Thorpe, T., Dingle, A., Cabalag, C., Loi, K., Fisher, O. M., Ward, S., Read, M., Johnson, M., Bassari, R., Bui, H., Cecconello, I., Sallum, R. A. A., da Rocha, J. R. M., Lopes, L. R., Tercioti Jr, V., Coelho, J. D. S., Ferrer, J. A. P., Buduhan, G., Tan, L., Srinathan, S., Shea, P., Yeung, J., Allison, F., Carroll, P., Vargas-Barato, F., Gonzalez, F., Ortega, J., Nino-Torres, L., Beltr??n-Garc??a, T. C., Castilla, L., Pineda, M., Bastidas, A., G??mez-Mayorga, J., Cort??s, N., Cetares, C., Caceres, S., Duarte, S., Pazdro, A., Snajdauf, M., Faltova, H., Sevcikova, M., Mortensen, P. B., Katballe, N., Ingemann, T., Morten, B., Kruhlikava, I., Ainswort, A. P., Stilling, N. M., Eckardt, J., Holm, J., Thorsteinsson, M., Siemsen, M., Brandt, B., Nega, B., Teferra, E., Tizazu, A., Kauppila, J. H., Koivukangas, V., Meril??inen, S., Gruetzmann, R., Krautz, C., Weber, G., Golcher, H., Emons, G., Azizian, A., Ebeling, M., Niebisch, S., Kreuser, N., Albanese, G., Hesse, J., Volovnik, L., Boecher, U., Reeh, M., Triantafyllou, S., Schizas, D., Michalinos, A., Balli, E., Mpoura, M., Charalabopoulos, A., Manatakis, D. K., Balalis, D., Bolger, J., Baban, C., Mastrosimone, A., Mcanena, O., Quinn, A., S??illeabh??in, C. B., Hennessy, M. M., Ivanovski, I., Khizer, H., Ravi, N., Donlon, N., Cervellera, M., Vaccari, S., Bianchini, S., Asti, E., Bernardi, D., Merigliano, S., Provenzano, L., Scarpa, M., Saadeh, L., Salmaso, B., De Manzoni, G., Giacopuzzi, S., La Mendola, R., De Pasqual, C. A., Tsubosa, Y., Niihara, M., Irino, T., Makuuchi, R., Ishii K, K., Mwachiro, M., Fekadu, A., Odera, A., Mwachiro, E., Alshehab, D., Ahmed, H. A., Shebani, A. O., Elhadi, A., Elnagar, F. A., Elnagar, H. F., Makkai-Popa, S. T., Wong, L. F., Tan, Y. R., Thannimalai, S., C. A., Ho, Pang, W. S., Tan, J. H., Basave, H. N. L., Cort??s-Gonz??lez, R., Lagarde, S. M., van Lanschot, J. J. B., Cords, C., Jansen, W. A., Martijnse, I., Matthijsen, R., Bouwense, S., Klarenbeek, B., Verstegen, M., van Workum, F., Ruurda, J. P., van der Sluis, P. C., de Maat, M., Evenett, N., Johnston, P., Patel, R., Maccormick, A., Smith, B., Ekwunife, C., Memon, A. H., Shaikh, K., Wajid, A., Khalil, N., Haris, M., Mirza, Z. U., Qudus, S. B. A., Sarwar, M. Z., Shehzadi, A., Raza, A., Jhanzaib, M. H., Farmanali, J., Zakir, Z., Shakeel, O., Nasir, I., Khattak, S., Baig, M., Noor, M. A., Ahmed, H. H., Naeem, A., Pinho, A. C., da Silva, R., Bernardes, A., Campos, J. C., Matos, H., Braga, T., Monteiro, C., Ramos, P., Cabral, F., Gomes, M. P., Martins, P. C., Correia, A. M., Videira, J. F., Ciuce, C., Drasovean, R., Apostu, R., Paitici, S., Racu, A. E., Obleaga, C. V., Beuran, M., Stoica, B., Ciubotaru, C., Negoita, V., Cordos, I., Birla, R. D., Predescu, D., Hoara, P. A., Tomsa, R., Shneider, V., Agasiev, M., Ganjara, I., Gunji??, D., Veselinovi??, M., Babi??, T., Chin, T. S., Shabbir, A., Kim, G., Crnjac, A., Samo, H., D??ez del Val, I., Leturio, S., Ram??n, J. M., Dal Cero, M., Rif??, S., Rico, M., Pagan Pomar, A., Martinez Corcoles, J. A., Rodicio Miravalles, J. L., Pais, S. A., Turienzo, S. A., Alvarez, L. S., Campos, P. V., Rendo, A. G., Garc??a, S. S., Santos, E. P. G., Mart??nez, E. T., Fern??ndez D??az, M. J., lvarez, C. Magad??n., Mart??n, V. Concepci??n., D??az L??pez, C., Rosat Rodrigo, A., P??rez S??nchez, L. E., Cuadrado, M. Bail??n., Tinoco Carrasco, C., Choolani Bhojwani, E., S??nchez, D. P., Ahmed, M. E., Dzhendov, T., Lindberg, F., Ruteg??rd, M., Sundbom, M., Mickael, C., Colucci, N., Schnider, A., Er, S., Kurnaz, E., Turkyilmaz, S., Turkyilmaz, A., Yildirim, R., Baki, B. E., Akkapulu, N., Karahan, O., Damburaci, N., Hardwick, R., Safranek, P., Sujendran, V., Bennett, J., Afzal, Z., Shrotri, M., Chan, B., Exarchou, K., Gilbert, T., Amalesh, T., Mukherjee, D., Mukherjee, S., Wiggins, T. H., Kennedy, R., Mccain, S., Harris, A., Dobson, G., Davies, N., Wilson, I., Mayo, D., Bennett, D., Young, R., Manby, P., Blencowe, N., Schiller, M., Byrne, B., Mitton, D., Wong, V., Elshaer, A., Cowen, M., Menon, V., Tan, L. C., Mclaughlin, E., Koshy, R., Sharp, C., Brewer, H., Das, N., Cox, M., Al Khyatt, W., Worku, D., Iqbal, R., Walls, L., Mcgregor, R., Fullarton, G., Macdonald, A., Mackay, C., Craig, C., Dwerryhouse, S., Hornby, S., Jaunoo, S., Wadley, M., Baker, C., Saad, M., Kelly, M., Davies, A., Di Maggio, F., Mistry, P., Singhal, R., Tucker, O., Kapoulas, S., Powell-Brett, S., Davis, P., Bromley, G., Watson, L., Verma, R., Ward, J., Shetty, V., Ball, C., Pursnani, K., Sarela, A., Sue Ling, H., Mehta, S., Hayden, J., To, N., Palser, T., Hunter, D., Supramaniam, K., Butt, Z., Ahmed, A., Kumar, S., Chaudry, A., Moussa, O., Kordzadeh, A., Lorenzi, B., Wilson, M., Patil, P., Noaman, I., Bouras, G., Evans, R., Singh, M., Warrilow, H., Ahmad, A., Tewari, N., Yanni, F., Couch, J., Theophilidou, E., Reilly, J. J., van Boxel, G., Akbari, K., Zanotti, D., Sanders, G., Wheatley, T., Ariyarathenam, A., Reece-Smith, A., Humphreys, L., Choh, C., Carter, N., Knight, B., Pucher, P., Athanasiou, A., Tan, B., Abdulrahman, M., Vickers, J., Akhtar, K., Chaparala, R., Brown, R., Alasmar, M. M. A., Ackroyd, R., Patel, K., Tamhankar, A., Wyman, A., Walker, R., Grace, B., Abbassi, N., Slim, N., Ioannidi, L., Blackshaw, G., Havard, T., Escofet, X., Powell, A., Owera, A., Rashid, F., Jambulingam, P., Padickakudi, J., Ben-Younes, H., Mccormack, K., Makey, I. A., Karush, M. K., Seder, C. W., Liptay, M. J., Chmielewski, G., Rosato, E. L., Berger, A. C., Zheng, R., Okolo, E., Singh, A., Scott, C. D., Weyant, M. J., Mitchell, J. D., and Surgery
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Male ,Textbook ,MINIMALLY INVASIVE ESOPHAGECTOMY ,Minimally Invasive Surgical Procedures/methods ,Esophageal Neoplasms ,SURGERY ,Anastomosis ,LYMPH-NODE RETRIEVAL ,Anastomosis, Surgical ,education ,Anastomosis, Surgical/adverse effects ,Esophageal Neoplasms/pathology ,Esophagectomy/methods ,Cohort Studies ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,Treatment Outcome ,SDG 3 - Good Health and Well-being ,Humans ,Minimally Invasive Surgical Procedures ,Esophagectomy ,Surgical ,esophagectomy ,Surgery ,Textbook, esophagectomy, esophageal cancer ,esophageal cancer - Abstract
Background Textbook outcome has been proposed as a tool for the assessment of oncological surgical care. However, an international assessment in patients undergoing oesophagectomy for oesophageal cancer has not been reported. This study aimed to assess textbook outcome in an international setting. Methods Patients undergoing curative resection for oesophageal cancer were identified from the international Oesophagogastric Anastomosis Audit (OGAA) from April 2018 to December 2018. Textbook outcome was defined as the percentage of patients who underwent a complete tumour resection with at least 15 lymph nodes in the resected specimen and an uneventful postoperative course, without hospital readmission. A multivariable binary logistic regression model was used to identify factors independently associated with textbook outcome, and results are presented as odds ratio (OR) and 95 per cent confidence intervals (95 per cent c.i.). Results Of 2159 patients with oesophageal cancer, 39.7 per cent achieved a textbook outcome. The outcome parameter ‘no major postoperative complication’ had the greatest negative impact on a textbook outcome for patients with oesophageal cancer, compared to other textbook outcome parameters. Multivariable analysis identified male gender and increasing Charlson comorbidity index with a significantly lower likelihood of textbook outcome. Presence of 24-hour on-call rota for oesophageal surgeons (OR 2.05, 95 per cent c.i. 1.30 to 3.22; P = 0.002) and radiology (OR 1.54, 95 per cent c.i. 1.05 to 2.24; P = 0.027), total minimally invasive oesophagectomies (OR 1.63, 95 per cent c.i. 1.27 to 2.08; P < 0.001), and chest anastomosis above azygous (OR 2.17, 95 per cent c.i. 1.58 to 2.98; P < 0.001) were independently associated with a significantly increased likelihood of textbook outcome. Conclusion Textbook outcome is achieved in less than 40 per cent of patients having oesophagectomy for cancer. Improvements in centralization, hospital resources, access to minimal access surgery, and adoption of newer techniques for improving lymph node yield could improve textbook outcome.
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- 2022
29. MiRNAs expression pattern and machine learning models elucidate risk for gastric GIST
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Stefanou, I.K. Dovrolis, N. Gazouli, M. Theodorou, D. Zografos, G.K. Toutouzas, K.G.
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neoplasms ,digestive system diseases - Abstract
BACKGROUND: Gatrointestinal stromal tumors (GISTs) are the main mesenchymal tumors found in the gastrointestinal system. GISTs clinical phenotypes differ significantly and their molecular basis is not yet completely known. microRNAs (miRNAs) have been involved in carcinogenesis pathways by regulating gene expression at post-transcriptional level. OBJECTIVE: The aim of the present study was to elucidate the expression profiles of miRNAs relevant to gastric GIST carcinogenesis, and to identify miRNA signatures that can discriminate the GIST from normal cases. METHODS: miRNA expression was tested by miScript™miRNA PCR Array Human Cancer PathwayFinder kit and then we used machine learning in order to find a miRNA profile that can predict the risk for GIST development. RESULTS: A number of miRNAs were found to be differentially expressed in GIST cases compared to healthy controls. Among them the hsa-miR-218-5p was found to be the best predictor for GIST development in our cohort. Additionally, hsa-miR-146a-5p, hsa-miR-222-3p, and hsa-miR-126-3p exhibit significantly lower expression in GIST cases compared to controls and were among the top predictors in all our predictive models. CONCLUSIONS: A machine learning classification approach may be accurate in determining the risk for GIST development in patients. Our findings indicate that a small number of miRNAs, with hsa-miR218-5p as a focus, may strongly affect the prognosis of GISTs. © 2022 - IOS Press. All rights reserved.
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- 2022
30. Sofortrekonstruktion der Brust mit freiem, mikrovaskulärem 'TRAM flap'
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Gabka, C. J., Maiwald, G., Theodorou, D., Bohmert, H., Hartel, W., editor, and Pichlmayr, R.
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- 1996
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31. Coverage interval estimation of the measurement of Gross Heat of Combustion of fuel by bomb calorimetry: Comparison of ISO GUM and adaptive Monte Carlo method
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Theodorou, D., Zannikou, Y., Anastopoulos, G., and Zannikos, F.
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- 2011
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32. Atomistic Monte Carlo simulation and continuum mean field theory of the structure and equation of state properties of alkane and polymer melts
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Dodd, L. R., Theodorou, D. N., Abe, Akihiro, editor, Benoit, Henri, editor, Cantow, Hans-Joachim, editor, Corradini, Paolo, editor, Dušek, Karel, editor, Edwards, Sam, editor, Fujita, Hiroshi, editor, Glöckner, Gottfried, editor, Höcker, Hartwig, editor, Hörhold, Hans-Heinrich, editor, Kausch, Hans-Henning, editor, Kennedy, Joseph P., editor, Koenig, Jack L., editor, Ledwith, Anthony, editor, McGrath, J. E., editor, Monnerie, Lucien, editor, Okamura, Seizo, editor, Overberger, Charles G., editor, Ringsdorf, Helmut, editor, Saegusa, Takeo, editor, Salamone, J. C., editor, Schrag, John L., editor, Wegner, G., editor, and Suter, U. W., editor
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- 1994
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33. 5GZORRO_D2.2: Design of the 5GZORRO Platform for Security & Trust
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Carrozzo, P.G. Giardina, J. Brenes, E. Bucchianeri, G. Landi, C. Herranz, A. Fernandez, M. S. Siddiqui, Javier Fernandez, K. Meth, K. Barabash, Diego R. López, P. Diogo, L. Conceicao, T. Subramanya, R. Behravesh, J.M. Jorquera Valero, P. M. Sánchez Sánchez, M. Gil Pérez, G. Martínez Pérez, J. Taylor, J. Bonnet, P. Chainho, M. Mertiri, T. Bozios, A. Lekidis, V. Theodorou, D. Laskaratos, F. Bravo Díaz, A. Ramos, J.M. Mifsud, A. Sciberreas
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This document presents the first version of the 5GZORRO high-level architecture, EC approval: 08/10/2021
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- 2021
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34. rAAV vermittelter Gentransfer in Gefäßendothel in vitro und in vivo
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Stangl, M. J., Theodorou, D., Hacker, U., Gerner, F., Wildhirt, S., Reichenspurner, H., Hallek, M., Schildberg, F. W., Encke, A., editor, Rothmund, M., editor, Hartel, W., editor, and Beger, Hans G., editor
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- 2000
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35. Postoperative and Pathological Outcomes of CROSS and FLOT as Neoadjuvant Therapy for Esophageal and Junctional Adenocarcinoma
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Committee:, Steering, Alderson, D, Bundred, J, RPT, Evans, Gossage, J, Griffiths, EA, Jefferies, B, Kamarajah, SK, McKay, S, Mohamed, Nepogodiev, D, Siaw- Acheampong, K, Singh, P, van Hillegersberg, R, Vohra, R, Wanigasooriya, K, Whitehouse, T., Leads:, National, Gjata, A, Moreno, JI, Takeda, FR, Kidane, B, Guevara Castro, R, Harustiak, T, Bekele, A, Kechagias, A, Gockel, Kennedy, A, Da Roit, A, Bagajevas, A, Azagra, JS, Mahendran, HA, Mejía-Fernández, L, Wijnhoven, BPL, El Kafsi, J, Sayyed, RH, Sousa, M, Sampaio, AS, Negoi, Blanco, R, Wallner, B, Schneider, PM, Hsu, PK, Isik, A, Leads:, Site, Gananadha, S, Wills, Devadas, M, Duong, C, Talbot, M, Hii, MW, Jacobs, R, Andreollo, NA, Johnston, B, Darling, G, Isaza-Restrepo, A, Rosero, G, Arias- Amézquita, F, Raptis, D, Gaedcke, J, Reim, D, Izbicki, J, Egberts, JH, Dikinis, S, Kjaer, DW, Larsen, MH, Achiam, MP, Saarnio, J, Theodorou, D, Liakakos, T, Korkolis, DP, Robb, WB, Collins, C, Murphy, T, Reynolds, J, Tonini, Migliore, M, Bonavina, L, Valmasoni, M, Bardini, R, Weindelmayer, J, Terashima, M, White, RE, Alghunaim, E, Elhadi, M, Leon-Takahashi, AM, Medina-Franco, H, Lau, PC, Okonta, KE, Heisterkamp, J, Rosman, C, van Hillegersberg, R, Beban, G, Babor, R, Gordon, A, Rossaak, JI, Pal, KMI, Qureshi, AU, Naqi, SA, Syed, AA, Barbosa, J, Vicente, CS, Leite, J, Freire, J, Casaca, R, Costa, RCT, Scurtu, RR, Mogoanta, SS, Bolca, C, Constantinoiu, S, Sekhniaidze, D, Bjelović, M, So, JBY, Gačevski, G, Loureiro, C, Pera, M, Bianchi, A, Moreno Gijón, M, Martín Fernández, J, Trugeda Carrera, MS, Vallve-Bernal, M, Cítores Pascual, MA, Elmahi, S, Halldestam, Hedberg, J, Mönig, S, Gutknecht, S, Tez, M, Guner, A, Tirnaksiz, MB, Colak, E, Sevinç, B, Hindmarsh, A, Khan, Khoo, D, Byrom, R, Gokhale, J, Wilkerson, P, Jain, P, Chan, D, Robertson, K, Iftikhar, S, Skipworth, R, Forshaw, M, Higgs, S, Gossage, J, Nijjar, R, Viswanath, YKS, Turner, P, Dexter, S, Boddy, A, Allum, WH, Oglesby, S, Cheong, E, Beardsmore, D, Vohra, R, Maynard, N, Berrisford, R, Mercer, S, Puig, S, Melhado, R, Kelty, C, Underwood, T, Dawas, K, Lewis, W, Al-Bahrani, A, Bryce, G, Thomas, M, Arndt, AT, Palazzo, F, Meguid, RA, Collaborators:, Fergusson, J, Beenen, E, Mosse, C, Salim, J, Cheah, S, Wright, T, Cerdeira, MP, McQuillan, P, Richardson, M, Liem, H, Spillane, J, Yacob, M, Albadawi, F, Thorpe, T, Dingle, A, Cabalag, C, Loi, K, Fisher, OM, Ward, S, Read, M, Johnson, M, Bassari, R, Bui, H, Cecconello, RAA, Sallum, da Rocha, JRM, Lopes, LR, Tercioti, V, JDS, Coelho, Ferrer, JAP, Buduhan, G, Tan, L, Srinathan, S, Shea, P, Yeung, J, Allison, F, Carroll, P, Vargas-Barato, F, Gonzalez, F, Ortega, J, Nino-Torres, L, Beltrán-García, TC, Castilla, L, Pineda, M, Bastidas, A, Gómez-Mayorga, J, Cortés, N, Cetares, C, Caceres, S, Duarte, S, Pazdro, A, Snajdauf, M, Faltova, H, Sevcikova, M, Mortensen, PB, Katballe, N, Ingemann, T, Kruhlikava, Morten B, Ainswort, AP, Stilling, NM, Eckardt, J, Holm, J, Thorsteinsson, M, Siemsen, M, Brandt, B, Nega, B, Teferra, E, Tizazu, A, Kauppila, JH, Koivukangas, V, Meriläinen, S, Gruetzmann, R, Krautz, C, Weber, G, Golcher, H, Emons, G, Azizian, A, Ebeling, M, Niebisch, S, Kreuser, N, Albanese, G, Hesse, J, Volovnik, L, Boecher, U, Reeh, M, Triantafyllou, S, Schizas, D, Michalinos, A, Balli, E, Mpoura, M, Charalabopoulos, A, Manatakis, DK, Balalis, D, Bolger, J, Baban, C, Mastrosimone, A, McAnena, O, Quinn, A, Ó Súilleabháin, CB, Hennessy, MM, Ivanovski, Khizer, H, Ravi, N, Donlon, N, Cervellera, M, Vaccari, S, Bianchini, S, Sartarelli, l, Asti, E, Bernardi, D, Merigliano, S, Provenzano, L, Scarpa, M, Saadeh, L, Salmaso, B, De Manzoni, G, Giacopuzzi, S, Mendola, La, De Pasqual, CA, Tsubosa, Y, Niihara, M, Irino, T, Makuuchi, R, Ishii, K, Mwachiro, M, Fekadu, A, Odera, A, Mwachiro, E, AlShehab, D, Ahmed, HA, Shebani, AO, Elhadi, A, Elnagar, FA, Elnagar, HF, Makkai-Popa, ST, Wong, LF, Tan, YR, Thannimalai, S, Ho, CA, Pang, WS, Tan, JH, HNL, Basave, Cortés-González, R, Lagarde, SM, van Lanschot, JJB, Cords, C, Jansen, WA, Martijnse, I, Matthijsen, R, Bouwense, S, Klarenbeek, B, Verstegen, M, van Workum, F, Ruurda, JP, van der Sluis, PC, de Maat, M, Evenett, N, Johnston, P, Patel, R, MacCormick, A, Young, M, Smith, B, Ekwunife, C, Memon, AH, Shaikh, K, Wajid, A, Khalil, N, Haris, M, Mirza, ZU, SBA, Qudus, Sarwar, MZ, Shehzadi, A, Raza, A, Jhanzaib, MH, Farmanali, J, Zakir, Z, Shakeel, O, Nasir, Khattak, S, Baig, M, Noor, MA, Ahmed, HH, Naeem, A, Pinho, AC, da Silva, R, Bernardes, A, Campos, JC, Matos, H, Braga, T, Monteiro, C, Ramos, P, Cabral, F, Gomes, MP, Martins, PC, Correia, AM, Videira, JF, Ciuce, C, Drasovean, R, Apostu, R, Ciuce, C, Paitici, S, Racu, AE, Obleaga, CV, Beuran, M, Stoica, B, Negoita, Ciubotaru C, Cordos, Birla, RD, Predescu, D, Hoara, PA, Tomsa, R, Shneider, Agasiev, M, Ganjara, Gunjić, D, Veselinović, M, Babič, T, Chin, TS, Shabbir, A, Kim, G, Crnjac, A, Samo, H, Val, Díez del, Leturio, S, Ramón, JM, Dal Cero, M, Rifá, S, Rico, M, Pagan Pomar, A, Martinez Corcoles, JA, Rodicio Miravalles, JL, Pais, SA, Turienzo, SA, Alvarez, LS, Campos, PV, Rendo, AG, García, SS, EPG, Santos, Martínez, ET, Fernández Díaz, MJ, Magadán Álvarez, C, Martín, Concepción, Díaz López, C, Rosat Rodrigo, A, Pérez Sánchez, LE, Bailón Cuadrado, M, Tinoco Carrasco, C, Choolani Bhojwani, E, Sánchez, DP, Ahmed, ME, Dzhendov, T, Lindberg, F, Rutegård, M, Sundbom, M, Mickael, C, Colucci, N, Schnider, A, Er, S, Kurnaz, E, Turkyilmaz, S, Turkyilmaz, A, Yildirim, R, Baki, BE, Akkapulu, N, Karahan, O, Damburaci, N, Hardwick, R, Safranek, P, Sujendran, Bennett, J, Afzal, Z, Shrotri, M, Chan, B, Exarchou, K, Gilbert, T, Amalesh, T, Mukherjee, D, Mukherjee, S, Wiggins, TH, Kennedy, R, McCain, S, Harris, A, Dobson, G, Davies, N, Wilson, I, Mayo, D, Bennett, D, Young, R, Manby, P, Blencowe, N, Schiller, M, Byrne, B, Mitton, D, Wong, V, Elshaer, A, Cowen, M, Menon, Tan, LC, McLaughlin, E, Koshy, R, Sharp, C, Brewer, H, Das, N, Cox, M, Al Khyatt, W, Worku, D, Iqbal, R, Walls, L, McGregor, R, Fullarton, G, Macdonald, A, MacKay, C, Craig, C, Dwerryhouse, S, Hornby, S, Jaunoo, S, Wadley, M, Baker, C, Saad, M, Kelly, M, Davies, A, Di Maggio, F, McKay, S, Mistry, P, Singhal, R, Tucker, O, Kapoulas, S, Powell-Brett, S, Davis, P, Bromley, G, Watson, L, Verma, R, Ward, J, Shetty, V, Ball, C, Pursnani, K, Sarela, A, Sue Ling, H, Mehta, S, Hayden, J, To, N, Palser, T, Hunter, D, Supramaniam, K, Butt, Z, Ahmed, A, Kumar, S, Chaudry, A, Moussa, O, Kordzadeh, A, Lorenzi B Wilson, M, Patil, P, Noaman, Willem, J, Bouras, G, Evans, R, Singh, M, Warrilow, H, Ahmad, A, Tewari, N, Yanni, F, Couch, J, Theophilidou, E, Reilly, JJ, Singh, P, van Boxel, Gijs, Akbari, K, Zanotti, D, Sgromo, B, Sanders, G, Wheatley, T, Ariyarathenam, A, Reece-Smith, A, Humphreys, L, Choh, C, Carter, N, Knight, B, Pucher, P, Athanasiou, A, Mohamed, Tan, B, Abdulrahman, M, Vickers, J, Akhtar, K, Chaparala, R, Brown, R, Alasmar, MMA, Ackroyd, R, Patel, K, Tamhankar, A, Wyman, A, Walker, R, Grace, B, Abbassi, N, Slim, N, Ioannidi, L, Blackshaw, G, Havard, T, Escofet, X, Powell, A, Owera, A, Rashid, F, Jambulingam, P, Padickakudi, J, Ben-Younes, H, Mccormack, K, Makey, IA, Karush, MK, Seder, CW, Liptay, MJ, Chmielewski, G, Rosato, EL, Berger, AC, Zheng, R, Okolo, E, Singh, A, Scott, CD, Weyant, MJ, and Mitchell, JD.
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- 2023
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36. Barrett’s oesophagus and nissen fundoplication. The significance of postoperative oesophageal pH measurement
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Tsagaropoulos, N., Doulami, G., Kokoroskos, N., Triantafillou, S., Vrakopoulou, G. Z., Theodorou, D., and Zografos, G.
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- 2013
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37. Effect of Surface Nanopatterning on Slip: The Case of Couette Flow of Long-Chain Polyethylene Melt Flowing Past Gold Surfaces
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Sgouros, A. P., primary, Tsagkalakis, D. S., additional, and Theodorou, D. N., additional
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- 2021
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38. Long-Term Manometric Impact of the Adjustable Gastric Band on Esophageal Motility: a Prospective Case-Control Study
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Triantafyllou, T. Eleftheriou, M.M. Theodoropoulos, C. Schizas, D. Michalopoulos, N. Archontovasilis, F. Theodorou, D.
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- 2021
39. Mortality from esophagectomy for esophageal cancer across low, middle, and high-income countries: An international cohort study
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Kamarajah, S. K. Nepogodiev, D. Bekele, A. Cecconello, I. and Evans, R. P. T. Guner, A. Gossage, J. A. Harustiak, T. and Hodson, J. Isik, A. Kidane, B. Leon-Takahashi, A. M. and Mahendran, H. A. Negoi, I. Okonta, K. E. Rosero, G. and Sayyed, R. H. Singh, P. Takeda, F. R. van Hillegersberg, R. and Vohra, R. S. White, R. E. Griffiths, E. A. Alderson, D. and Bundred, J. Evans, R. P. T. Gossage, J. Griffiths, E. A. and Jefferies, B. Kamarajah, S. K. McKay, S. Mohamed, I. and Nepogodiev, D. Siaw-Acheampong, K. Singh, P. van Hillegersberg, R. Vohra, R. Wanigasooriya, K. Whitehouse, T. and Gjata, A. Moreno, J. I. Takeda, F. R. Kidane, B. and Guevara, Castro R. Harustiak, T. Bekele, A. Kechagias, A. and Gockel, I. Kennedy, A. Da Roit, A. Bagajevas, A. and Azagra, J. S. Mahendran, H. A. Mejia-Fernandez, L. and Wijnhoven, B. P. L. El Kafsi, J. Sayyed, R. H. Sousa, M. and Sampaio, A. S. Negoi, I. Blanco, R. Wallner, B. and Schneider, P. M. Hsu, P. K. Isik, A. Gananadha, S. and Wills, V. Devadas, M. Duong, C. Talbot, M. Hii, M. W. and Jacobs, R. Andreollo, N. A. Johnston, B. Darling, G. and Isaza-Restrepo, A. Rosero, G. Arias-Amezquita, F. Raptis, D. and Gaedcke, J. Reim, D. Izbicki, J. Egberts, J. H. and Dikinis, S. Kjaer, D. W. Larsen, M. H. Achiam, M. P. and Saarnio, J. Theodorou, D. Liakakos, T. Korkolis, D. P. and Robb, W. B. Collins, C. Murphy, T. Reynolds, J. Tonini, V. Migliore, M. Bonavina, L. Valmasoni, M. Bardini, R. and Weindelmayer, J. Terashima, M. White, R. E. Alghunaim, E. Elhadi, M. Leon-Takahashi, A. M. Medina-Franco, H. and Lau, P. C. Okonta, K. E. Heisterkamp, J. Rosman, C. van Hillegersberg, R. Beban, G. Babor, R. Gordon, A. and Rossaak, J. I. Pal, K. M. I. Qureshi, A. U. Naqi, S. A. and Syed, A. A. Barbosa, J. Vicente, C. S. Leite, J. Freire, J. Casaca, R. Costa, R. C. T. Scurtu, R. R. Mogoanta, S. S. Bolca, C. Constantinoiu, S. Sekhniaidze, D. Bjelovic, M. So, J. B. Y. Gacevski, G. Loureiro, C. Pera, M. and Bianchi, A. Moreno, Gijon M. Martin Fernandez, J. Carrera, M. S. Trugeda Vallve-Bernal, M. Pascual, M. A. Citores and Elmahi, S. Halldestam, I. Hedberg, J. Monig, S. and Gutknecht, S. Tez, M. Guner, A. Tirnaksiz, M. B. Colak, E. Sevinc, B. Hindmarsh, A. Khan, I. Khoo, D. Byrom, R. Gokhale, J. Wilkerson, P. Jain, P. Chan, D. and Robertson, K. Iftikhar, S. Skipworth, R. Forshaw, M. and Higgs, S. Gossage, J. Nijjar, R. Viswanath, Y. K. S. and Turner, P. Dexter, S. Boddy, A. Allum, W. H. Oglesby, S. and Cheong, E. Beardsmore, D. Vohra, R. Maynard, N. and Berrisford, R. Mercer, S. Puigt, S. Melhadot, R. Kelty, C. Underwood, T. Dawas, K. Lewis, W. Al-Bahrani, A. and Bryce, G. Thomas, M. Arndt, A. T. Palazzo, F. Meguid, R. A. Fergusson, J. Beenen, E. Mosse, C. Salim, J. and Cheah, S. Wright, T. Cerdeira, M. P. McQuillan, P. and Richardson, M. Liem, H. Spillane, J. Yacob, M. Albadawi, F. Thorpe, T. Dingle, A. Cabalag, C. Loi, K. Fisher, O. M. Ward, S. Read, M. Johnson, M. Bassari, R. Bui, H. Cecconello, I. Sallum, R. A. A. da Rocha, J. R. M. and Lopes, L. R. Tercioti, Jr., V. Coelho, J. D. Ferrer, J. A. P. Buduhan, G. Tan, L. Srinathan, S. Shea, P. Yeung, J. Allison, F. Carroll, P. Vargas-Barato, F. Gonzalez, F. Ortega, J. Nino-Torres, L. Beltran-Garcia, T. C. and Castilla, L. Pineda, M. Bastidas, A. Gomez-Mayorga, J. and Cortes, N. Cetares, C. Caceres, S. Duarte, S. Pazdro, A. and Snajdauf, M. Faltova, H. Sevcikova, M. Mortensen, P. B. and Katballe, N. Ingemann, T. Morten, B. Kruhlikava, I. and Ainswort, A. P. Stilling, N. M. Eckardt, J. Holm, J. and Thorsteinsson, M. Siemsen, M. Brandt, B. Nega, B. and Teferra, E. Tizazu, A. Kauppila, J. H. Koivukangas, V. and Merilainen, S. Gruetzmann, R. Krautz, C. Weber, G. and Golcher, H. Emons, G. Azizian, A. Ebeling, M. Niebisch, S. Kreuser, N. Albanese, G. Hesse, J. Volovnik, L. and Boecher, U. Reeh, M. Triantafyllou, S. Schizas, D. and Michalinos, A. Mpali, E. Mpoura, M. Charalabopoulos, A. and Manatakis, D. K. Balalis, D. Bolger, J. Baban, C. and Mastrosimone, A. McAnena, O. Quinn, A. Suilleabhain, C. B. O. Hennessy, M. M. Ivanovski, I. Khizer, H. Ravi, N. and Donlon, N. Cervellera, M. Vaccari, S. Bianchini, S. and Sartarelli, L. Asti, E. Bernardi, D. Merigliano, S. and Provenzano, L. Scarpa, M. Saadeh, L. Salmaso, B. De Manzoni, G. Giacopuzzi, S. La Mendola, R. De Pasqual, C. A. and Tsubosa, Y. Niihara, M. Irino, T. Makuuchi, R. and Ishii, K. Mwachiro, M. Fekadu, A. Odera, A. Mwachiro, E. and AlShehab, D. Ahmed, H. A. Shebani, A. O. Elhadi, A. and Elnagar, F. A. Elnagar, H. F. Makkai-Popa, S. T. Wong, L. F. and Tan, Y. R. Thannimalai, S. Ho, C. A. Pang, W. S. and Tan, J. H. Basave, H. N. L. Cortes-Gonzalez, R. Lagarde, S. M. van Lanschot, J. J. B. Cords, C. Jansen, W. A. and Martijnse, I. Matthijsen, R. Bouwense, S. Klarenbeek, B. and Verstegen, M. van Workum, F. Ruurda, J. P. van der Sluis, P. C. de Maat, M. Evenett, N. Johnston, P. Patel, R. and MacCormick, A. Young, M. Smith, B. Ekwunife, C. Memon, A. H. Shaikh, K. Wajid, A. Khalil, N. Haris, M. and Mirza, Z. U. Qudus, S. B. A. Sarwar, M. Z. Shehzadi, A. and Raza, A. Jhanzaib, M. H. Farmanali, J. Zakir, Z. and Shakeel, O. Nasir, I. Khattak, S. Baig, M. Noor, M. A. and Ahmed, H. H. Naeem, A. Pinho, A. C. da Silva, R. and Bernardes, A. Campos, J. C. Matos, H. Braga, T. and Monteiro, C. Ramos, P. Cabral, F. Gomes, M. P. Martins, P. C. Correia, A. M. Videira, J. F. Ciuce, C. Drasovean, R. Apostu, R. Ciuce, C. Paitici, S. Racu, A. E. and Obleaga, C. V. Beuran, M. Stoica, B. Ciubotaru, C. and Negoita, V. Cordos, I. Birla, R. D. Predescu, D. Hoara, P. A. Tomsa, R. Shneider, V. Agasiev, M. Ganjara, I. and Gunjic, D. Veselinovic, M. Babic, T. Chin, T. S. and Shabbir, A. Kim, G. Crnjac, A. Samo, H. Del Val, I. Diez and Leturio, S. Ramon, J. M. Dal Cero, M. Rifa, S. Rico, M. Pomar, A. Pagan Corcoles, J. A. Martinez Miravalles, J. L. Rodicio Pais, S. A. Turienzo, S. A. Alvarezt, L. S. and Alvarez, L. S. Campos, P. V. Rendo, A. G. Garcia, S. S. and Santos, E. P. G. Martinez, E. T. Fernandez, Diaz Mj Magadan, Alvarez C. Concepcion, Martin V. Diaz, Lopez C. Rosat, Rodrigo A. Perez, Sanchez L. E. Bailon, Cuadrado M. Tinoco, Carrasco C. Bhojwani, E. Choolani Sanchez, D. P. Ahmed, M. E. Dzhendov, T. Lindberg, F. Rutegard, M. Sundbom, M. and Mickael, C. Colucci, N. Schnider, A. Er, S. Kurnaz, E. Turkyilmaz, S. Turkyilmaz, A. Yildirim, R. Baki, B. E. Akkapulu, N. Karahan, O. Damburaci, N. Hardwickt, R. and Safranek, P. Sujendran, V. Bennett, J. Afzal, Z. and Shrotri, M. Chan, B. Exarchou, K. Gilbert, T. Amalesh, T. Mukherjee, D. Mukherjee, S. Wiggins, T. H. Kennedy, R. McCain, S. Harris, A. Dobson, G. Davies, N. and Wilson, I. Mayo, D. Bennett, D. Young, R. Manby, P. and Blencowe, N. Schiller, M. Byrne, B. Mitton, D. Wong, V. and Elshaer, A. Cowen, M. Menon, V. Tan, L. C. and McLaughlin, E. Koshy, R. Sharp, C. Brewer, H. Das, N. and Cox, M. Al Khyatt, W. Worku, D. Iqbal, R. Walls, L. and McGregor, R. Fullarton, G. Macdonald, A. MacKay, C. and Craig, C. Dwerryhouse, S. Hornby, S. Jaunoo, S. Wadley, M. Baker, C. Saad, M. Kelly, M. Davies, A. Di Maggio, F. McKay, S. Mistry, P. Singhal, R. Tucker, O. and Kapoulas, S. Powell-Brett, S. Davis, P. Bromley, G. and Watson, L. Verma, R. Ward, J. Shetty, V. Ball, C. and Pursnani, K. Sarela, A. Sue, Ling H. Mehta, S. Hayden, J. To, N. Palser, T. Hunter, D. Supramaniam, K. and Butt, Z. Ahmed, A. Kumar, S. Chaudry, A. Moussa, O. and Kordzadeh, A. Lorenzi, B. Wilson, M. Patil, P. Noaman, I. Willem, J. Bouras, G. Evans, R. Singh, M. and Warrilow, H. Ahmad, A. Tewari, N. Yanni, F. Couch, J. and Theophilidou, E. Reilly, J. J. Singh, P. van Boxel, Gijs and Akbari, K. Zanotti, D. Sgromo, B. Sanders, G. and Wheatley, T. Ariyarathenam, A. Reece-Smith, A. Humphreys, L. and Choh, C. Carter, N. Knight, B. Pucher, P. and Athanasiou, A. Mohamed, I. Tan, B. Abdulrahman, M. and Vickers, J. Akhtar, K. Chaparala, R. Brown, R. Alasmar, M. M. A. Ackroyd, R. Patel, K. Tamhankar, A. Wyman, A. and Walker, R. Grace, B. Abbassi, N. Slim, N. Ioannidi, L. Blackshaw, G. Havard, T. Escofet, X. Powell, A. and Owera, A. Rashid, F. Jambulingam, P. Padickakudi, J. and Ben-Younes, H. Mccormack, K. Makey, I. A. Karush, M. K. and Seder, C. W. Liptay, M. J. Chmielewski, G. Rosato, E. L. and Berger, A. C. Zheng, R. Okolo, E. Singh, A. Scott, C. D. and Weyant, M. J. Mitchell, J. D. Oesophago-Gastric Anastomotic
- Abstract
Background: No evidence currently exists characterising global outcomes following major cancer surgery, including esophageal cancer. Therefore, this study aimed to characterise impact of high income countries (HIC) versus low and middle income countries (LMIC) on the outcomes following esophagectomy for esophageal cancer. Method: This international multi-center prospective study across 137 hospitals in 41 countries included patients who underwent an esophagectomy for esophageal cancer, with 90-day follow-up. The main explanatory variable was country income, defined according to the World Bank Data classification. The primary outcome was 90-day postoperative mortality, and secondary outcomes were composite leaks (anastomotic leak or conduit necrosis) and major complications (Clavien-Dindo Grade III-V). Multivariable generalized estimating equation models were used to produce adjusted odds ratios (ORs) and 95% confidence intervals (CI95%). Results: Between April 2018 to December 2018, 2247 patients were included. Patients from HIC were more significantly older, with higher ASA grade, and more advanced tumors. Patients from LMIC had almost three-fold increase in 90-day mortality, compared to HIC (9.4% vs 3.7%, p < 0.001). On adjusted analysis, LMIC were independently associated with higher 90-day mortality (OR: 2.31, CI95%: 1.17-4.55, p = 0.015). However, LMIC were not independently associated with higher rates of anastomotic leaks (OR: 1.06, CI95%: 0.57-1.99, p = 0.9) or major complications (OR: 0.85, CI95%: 0.54-1.32, p = 0.5), compared to HIC. Conclusion: Resections in LMIC were independently associated with higher 90-day postoperative mortality, likely reflecting a failure to rescue of these patients following esophagectomy, despite similar composite anastomotic leaks and major complication rates to HIC. These findings warrant further research, to identify potential issues and solutions to improve global outcomes following esophagectomy for cancer. (C) 2020 Elsevier Ltd, BASO similar to The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.
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- 2021
40. Eosinophilic Esophagitis and Achalasia: Two Distinct Nosologic Entities or a Possible Etiopathogenic Association?
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Schizas, D. Syllaios, A. Vailas, M. Sotiropoulou, M. Triantafyllou, T. Tsapralis, D. Papanikolaou, I.S. Theodorou, D.
- Abstract
Background: Despite the fact that researchers have made significant progress in elucidating the pathophysiology of esophageal diseases, the understanding of esophageal motility alterations in patients with eosinophilic esophagitis (EoE) is in its infancy and current published medical literature remains rather scarce on this topic. A growing body of scientific data regarding associations between esophageal motor disorders, such as achalasia and EoE, exists nowadays. Summary: It seems that the association of EoE and achalasia does not constitute a cause and effect relationship, as it is not clear whether esophageal motility abnormalities are the result of EoE or vice versa. As such, there is no universally accepted treatment algorithm for patients presenting with both of these entities. Key Messages: The aim of this article is to review the existing data on achalasia-like motility disorders in patients with EoE, highlighting a possible association between these 2 esophageal disorders. Moreover, we seek to describe the clinical presentation in such cases, diagnostic modalities to be used, and current treatment strategies in patients suspected to suffer from both disorders. © 2021
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- 2021
41. Quality of Life of Haemodialysis Patients and Complications of CVC and AA
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Theodorou D, Papasavva A, and Kalli A
- Abstract
Background: The increase in life expectancy, as well as in chronic diseases, has resulted in giving emphasis not only to medical interventions, but to the continuous care of the patient. The measurement of Quality of Life (QOL) of haemodialysis patients provides information relevant to their needs and the consequences of haemodialysis in their life, which could be used to implement interventions that will lead to the improvement of their QOL.
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- 2021
42. Postoperative outcomes in oesophagectomy with trainee involvement
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Evans, R. P. T. Hodson, J. Kamarajah, S. K. Griffiths, E. A. and Singh, P. Alderson, D. Bundred, J. Gossage, J. and Jefferies, B. McKay, S. Mohamed, I Nepogodiev, D. and Siaw-Acheampong, K. van Hillegersberg, R. Vohra, R. and Wanigasooriya, K. Whitehouse, T. Gjata, A. Moreno, I, J. and Takeda, F. R. Kidane, B. Castro, R. Guevara Harustiak, T. and Bekele, A. Kechagias, A. Gockel, I Kennedy, A. Da Roit, A. Bagajevas, A. Azagra, J. S. Mahendran, H. A. and Mejia-Fernandez, L. Wijnhoven, B. P. L. El Kafsi, J. Sayyed, R. H. Sousa, M. Sampaio, A. S. Negoi, I Blanco, R. and Wallner, B. Schneider, P. M. Hsu, P. K. Isik, A. and Gananadha, S. Wills, V Devadas, M. Duong, C. Talbot, M. and Hii, M. W. Jacobs, R. Andreollo, N. A. Johnston, B. and Darling, G. Isaza-Restrepo, A. Rosero, G. Arias-Amezquita, F. Raptis, D. Gaedcke, J. Reim, D. Izbicki, J. and Egberts, J. H. Dikinis, S. Kjaer, D. W. Larsen, M. H. and Achiam, M. P. Saarnio, J. Theodorou, D. Liakakos, T. and Korkolis, D. P. Robb, W. B. Collins, C. Murphy, T. and Reynolds, J. Tonini, V Migliore, M. Bonavina, L. and Valmasoni, M. Bardini, R. Weindelmayer, J. Terashima, M. and White, R. E. Alghunaim, E. Elhadi, M. Leon-Takahashi, A. M. and Medina-Franco, H. Lau, P. C. Okonta, K. E. Heisterkamp, J. Rosman, C. Beban, G. Babor, R. Gordon, A. and Rossaak, I, J. Pal, I, K. M. Qureshi, A. U. Naqi, S. A. and Syed, A. A. Barbosa, J. Vicente, C. S. Leite, J. Freire, J. Casaca, R. Costa, R. C. T. Scurtu, R. R. Mogoanta, S. S. Bolca, C. Constantinoiu, S. Sekhniaidze, D. So, J. B. Y. Gacvski, G. Loureiro, C. Pera, M. Bianchi, A. and Gijon, M. Moreno Fernandez, J. Martin Carrera, M. S. Trugeda and Vallve-Bernal, M. Pascual, M. A. Citores Elmahi, S. and Halldestam, I Hedberg, J. Monig, S. Gutknecht, S. Tez, M. Guner, A. Tirnaksiz, T. B. Colak, E. Sevinc, B. and Hindmarsh, A. Khan, I Khoo, D. Byrom, R. Gokhale, J. and Wilkerson, P. Jain, P. Chan, D. Robertson, K. Iftikhar, S. Skipworth, R. Forshaw, M. Higgs, S. Nijjar, R. and Viswanath, Y. K. S. Turner, P. Dexter, S. Boddy, A. and Allum, W. H. Oglesby, S. Cheong, E. Beardsmore, D. and Maynard, N. Berrisford, R. Mercer, S. Puig, S. Melhado, R. Kelty, C. Underwood, T. Dawas, K. Lewis, W. and Al-Bahrani, A. Bryce, G. Thomas, M. Arndt, A. T. and Palazzo, F. Meguid, R. A. Fergusson, J. Beenen, E. and Mosse, C. Salim, J. Cheah, S. Wright, T. Cerdeira, M. P. and McQuillan, P. Richardson, M. Liem, H. Spillane, J. and Yacob, M. Albadawi, F. Thorpe, T. Dingle, A. Cabalag, C. and Loi, K. Fisher, O. M. Ward, S. Read, M. Johnson, M. and Bassari, R. Bui, H. Cecconello, I Sallum, R. A. A. and da Rocha, J. R. M. Lopes, L. R. Tercioti, Jr., V. Coelho, J. D. S. Ferrer, J. A. P. Buduhan, G. Tan, L. Srinathan, S. and Shea, P. Yeung, J. Allison, F. Carroll, P. and Vargas-Barato, F. Gonzalez, F. Ortega, J. Nino-Torres, L. and Beltran-Garcia, T. C. Castilla, L. Pineda, M. Bastidas, A. Gomez-Mayorga, J. Cortes, N. Cetares, C. Caceres, S. and Duarte, S. Pazdro, A. Snajdauf, M. Faltova, H. and Sevcikova, M. Mortensen, P. B. Katballe, N. Ingemann, T. and Morten, B. Kruhlikava, I Ainswort, A. P. Stilling, N. M. and Eckardt, J. Holm, J. Thorsteinsson, M. Siemsen, M. and Brandt, B. Nega, B. Teferra, E. Tizazu, A. Kauppila, J. S. Koivukangas, V Merilainen, S. Gruetzmann, R. Krautz, C. Weber, G. Golcher, H. Emons, G. Azizian, A. and Ebeling, M. Niebisch, S. Kreuser, N. Albanese, G. Hesse, J. Volovnik, L. Boecher, U. Reeh, M. Triantafyllou, S. and Schizas, D. Michalinos, A. Baili, E. Mpoura, M. and Charalabopoulos, A. Manatakis, D. K. Balalis, D. Bolger, J. and Baban, C. Mastrosimone, A. McAnena, O. Quinn, A. and Suilleabhain, C. B. O. Hennessy, M. M. Ivanovski, I. Khizer, H. Ravi, N. Donlon, N. Cervellera, M. Vaccari, S. and Bianchini, S. Sartarelli, L. Asti, E. Bernardi, D. and Merigliano, S. Provenzano, L. Scarpa, M. Saadeh, L. and Salmaso, B. De Manzoni, G. Giacopuzzi, S. La Mendola, R. and De Pasqual, C. A. Tsubosa, Y. Niihara, M. Irino, T. and Makuuchi, R. Ishii, K. Mwachiro, M. Fekadu, A. Odera, A. and Mwachiro, E. AlShehab, D. Ahmed, H. A. Shebani, A. O. and Elhadi, A. Elnagar, F. A. Elnagar, H. F. Makkai-Popa, S. T. Wong, L. F. Yunrong, T. Thanninalai, S. Aik, H. C. and Soon, P. W. Huei, T. J. Basave, H. N. L. and Cortes-Gonzalez, R. Lagarde, S. M. van Lanschot, J. J. B. and Cords, C. Jansen, W. A. Martijnse, I Matthijsen, R. and Bouwense, S. Klarenbeek, B. Verstegen, M. van Workum, F. and Ruurda, J. P. van der Veen, A. van den Berg, J. W. Evenett, N. Johnston, P. Patel, R. MacCormick, A. Young, M. and Smith, B. Ekwunife, C. Memon, A. H. Shaikh, K. Wajid, A. and Khalil, N. Haris, M. Mirza, Z. U. Qudus, S. B. A. and Sarwar, M. Z. Shehzadi, A. Raza, A. Jhanzaib, M. H. and Farmanali, J. Zakir, Z. Shakeel, O. Nasir, I Khattak, S. and Baig, M. Noor, M. A. Ahmed, H. H. Naeem, A. Pinho, A. C. da Silva, R. Bernardes, A. Campos, J. C. Matos, H. and Braga, T. Monteiro, C. Ramos, P. Cabral, F. Gomes, M. P. Martins, P. C. Correia, A. M. Videira, J. F. and Ciuce, C. Drasovean, R. Apostu, R. Paitici, S. Racu, A. E. Obleaga, V, C. Beuran, M. Stoica, B. Ciubotaru, C. and Negoita, V Cordos, I Birla, R. D. Predescu, D. and Hoara, P. A. Tomsa, R. Shneider, V Agasiev, M. Ganjara, I Gunjic, D. Veselinovic, M. Babic, T. Chin, T. S. and Shabbir, A. Kim, G. Crnjac, A. Samo, H. del Val, I. Diez and Leturio, S. Ramon, J. M. Dal Cero, M. Rifa, S. Rico, M. Pomar, A. Pagan Corcoles, J. A. Martinez Miravalles, J. L. Rodicio Pais, S. A. Turienzo, S. A. Alvarez, L. S. and Campos, V, P. Rendo, A. G. Garcia, S. S. Santos, E. P. G. and Martinez, E. T. Diaz, M. J. Fernandez Alvarez, C. Magadan and Martin, V. Concepcion Lopez, C. Diaz Rodrigo, A. Rosat and Sanchez, L. E. Perez Cuadrado, M. Bailon Carrasco, C. Tinoco and Bhojwani, E. Choolani Sanchez, D. P. Ahmed, M. E. Dzhendov, T. Lindberg, F. Rutegard, M. Sundbom, M. Mickael, C. and Colucci, N. Schnider, A. Er, S. Kurnaz, E. Turkyilmaz, S. Turkyilmaz, A. Yildirim, R. Baki, B. E. Akkapulu, N. and Karahan, O. Damburaci, N. Hardwick, R. Safranek, P. and Sujendran, V Bennett, J. Afzal, Z. Shrotri, M. Chan, B. and Exarchou, K. Gilbert, T. Amalesh, T. Mukherjee, D. and Mukherjee, S. Wiggins, T. H. Kennedy, R. McCain, S. and Harris, A. Dobson, G. Davies, N. Wilson, I Mayo, D. and Bennett, D. Young, R. Manby, P. Blencowe, N. Schiller, M. Byrne, B. Mitton, D. Wong, V Elshaer, A. Cowen, M. Menon, V Tan, L. C. McLaughlin, E. Koshy, R. and Sharp, C. Brewer, H. Das, N. Cox, M. Al Khyatt, W. and Worku, D. Iqbal, R. Walls, L. McGregor, R. Fullarton, G. and Macdonald, A. MacKay, C. Craig, C. Dwerryhouse, S. and Hornby, S. Jaunoo, S. Wadley, M. Baker, C. Saad, M. and Kelly, M. Davies, A. Di Maggio, F. Mistry, P. Singhal, R. Tucker, O. Kapoulas, S. Powell-Brett, S. Davis, P. and Bromley, G. Watson, L. Verma, R. Ward, J. Shetty, V and Ball, C. Pursnani, K. Sarela, A. Ling, H. Sue Mehta, S. Hayden, J. To, N. Palser, T. Hunter, D. and Supramaniam, K. Butt, Z. Ahmed, A. Kumar, S. Chaudry, A. and Moussa, O. Kordzadeh, A. Patil, P. Noaman, I Willem, J. Bouras, G. Evans, R. Singh, M. Warrilow, H. and Ahmad, A. Tewari, N. Yanni, F. Couch, J. Theophilidou, E. Reilly, J. J. van Boxel, G. Akbari, K. Zanotti, D. and Sgromo, B. Sanders, G. Wheatley, T. Ariyarathenam, A. and Reece-Smith, A. Humphreys, L. Choh, C. Carter, N. and Knight, B. Pucher, P. Athanasiou, A. Tan, B. and Abdulrahman, M. Vickers, J. Akhtar, K. Chaparala, R. and Brown, R. Alasmar, M. M. A. Ackroyd, R. Patel, K. and Tamhankar, A. Wyman, A. Walker, R. Grace, B. Abbassi, N. and Slim, N. Ioannidi, L. Blackshaw, G. Havard, T. and Escofet, X. Powell, A. Owera, A. Rashid, F. Jambulingam, P. Padickakudi, J. Ben-Younes, H. McCormack, K. Makey, I. A. Karush, M. K. Seder, C. W. Liptay, M. J. and Chmielewski, G. Rosato, E. L. Berger, A. C. Zheng, R. and Okolo, E. Singh, A. Scott, C. D. Weyant, M. J. Mitchell, J. D. West Midlands Res Collaborative
- Abstract
Background The complexity of oesophageal surgery and the significant risk of morbidity necessitates that oesophagectomy is predominantly performed by a consultant surgeon, or a senior trainee under their supervision. The aim of this study was to determine the impact of trainee involvement in oesophagectomy on postoperative outcomes in an international multicentre setting. Methods Data from the multicentre Oesophago-Gastric Anastomosis Study Group (OGAA) cohort study were analysed, which comprised prospectively collected data from patients undergoing oesophagectomy for oesophageal cancer between April 2018 and December 2018. Procedures were grouped by the level of trainee involvement, and univariable and multivariable analyses were performed to compare patient outcomes across groups. Results Of 2232 oesophagectomies from 137 centres in 41 countries, trainees were involved in 29.1 per cent of them (n = 650), performing only the abdominal phase in 230, only the chest and/or neck phases in 130, and all phases in 315 procedures. For procedures with a chest anastomosis, those with trainee involvement had similar 90-day mortality, complication and reoperation rates to consultant-performed oesophagectomies (P = 0.451, P = 0.318, and P = 0.382, respectively), while anastomotic leak rates were significantly lower in the trainee groups (P = 0.030). Procedures with a neck anastomosis had equivalent complication, anastomotic leak, and reoperation rates (P = 0.150, P = 0.430, and P = 0.632, respectively) in trainee-involved versus consultant-performed oesophagectomies, with significantly lower 90-day mortality in the trainee groups (P = 0.005). Conclusion Trainee involvement was not found to be associated with significantly inferior postoperative outcomes for selected patients undergoing oesophagectomy. The results support continued supervised trainee involvement in oesophageal cancer surgery. The aim of this study was to determine the impact of trainee involvement in oesophagectomy on perioperative outcomes in the international multicentre Oesophago-Gastric Anastomosis Audit (OGAA). Analysis of 2232 oesophagectomies has shown that trainee involvement did not negatively impact perioperative outcomes.
- Published
- 2021
43. Postoperative outcomes in oesophagectomy with trainee involvement
- Author
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Evans, R. P. (R. P. T.), Hodson, J. (J.), Kamarajah, S. K. (S. K.), Griffiths, E. A. (E. A.), Singh, P. (P.), Alderson, D. (D.), Bundred, J. (J.), Gossage, J. (J.), Jefferies, B. (B.), McKay, S. (S.), Mohamed, I. (I), Nepogodiev, D. (D.), Siaw-Acheampong, K. (K.), van Hillegersberg, R. (R.), Vohra, R. (R.), Wanigasooriya, K. (K.), Whitehouse, T. (T.), Gjata, A. (A.), Moreno, J. I. (J., I), Takeda, F. R. (F. R.), Kidane, B. (B.), Castro, R. G. (R. Guevara), Harustiak, T. (T.), Bekele, A. (A.), Kechagias, A. (A.), Gockel, I. (I), Kennedy, A. (A.), Da Roit, A. (A.), Bagajevas, A. (A.), Azagra, J. S. (J. S.), Mahendran, H. A. (H. A.), Mejia-Fernandez, L. (L.), Wijnhoven, B. P. (B. P. L.), El Kafsi, J. (J.), Sayyed, R. H. (R. H.), Sousa, M. (M.), Sampaio, A. S. (A. S.), Negoi, I. (I), Blanco, R. (R.), Wallner, B. (B.), Schneider, P. M. (P. M.), Hsu, P. K. (P. K.), Isik, A. (A.), Gananadha, S. (S.), Wills, V. (V), Devadas, M. (M.), Duong, C. (C.), Talbot, M. (M.), Hii, M. W. (M. 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(N.), Palser, T. (T.), Hunter, D. (D.), Supramaniam, K. (K.), Butt, Z. (Z.), Ahmed, A. (A.), Kumar, S. (S.), Chaudry, A. (A.), Moussa, O. (O.), Kordzadeh, A. (A.), Patil, P. (P.), Noaman, I. (I), Willem, J. (J.), Bouras, G. (G.), Evans, R. (R.), Singh, M. (M.), Warrilow, H. (H.), Ahmad, A. (A.), Tewari, N. (N.), Yanni, F. (F.), Couch, J. (J.), Theophilidou, E. (E.), Reilly, J. J. (J. J.), van Boxel, G. (G.), Akbari, K. (K.), Zanotti, D. (D.), Sgromo, B. (B.), Sanders, G. (G.), Wheatley, T. (T.), Ariyarathenam, A. (A.), Reece-Smith, A. (A.), Humphreys, L. (L.), Choh, C. (C.), Carter, N. (N.), Knight, B. (B.), Pucher, P. (P.), Athanasiou, A. (A.), Tan, B. (B.), Abdulrahman, M. (M.), Vickers, J. (J.), Akhtar, K. (K.), Chaparala, R. (R.), Brown, R. (R.), Alasmar, M. M. (M. M. A.), Ackroyd, R. (R.), Patel, K. (K.), Tamhankar, A. (A.), Wyman, A. (A.), Walker, R. (R.), Grace, B. (B.), Abbassi, N. (N.), Slim, N. (N.), Ioannidi, L. (L.), Blackshaw, G. (G.), Havard, T. (T.), Escofet, X. (X.), Powell, A. (A.), Owera, A. (A.), Rashid, F. (F.), Jambulingam, P. (P.), Padickakudi, J. (J.), Ben-Younes, H. (H.), McCormack, K. (K.), Makey, I. A. (I. A.), Karush, M. K. (M. K.), Seder, C. W. (C. W.), Liptay, M. J. (M. J.), Chmielewski, G. (G.), Rosato, E. L. (E. L.), Berger, A. C. (A. C.), Zheng, R. (R.), Okolo, E. (E.), Singh, A. (A.), Scott, C. D. (C. D.), Weyant, M. J. (M. J.), Mitchell, J. D. (J. D.), Evans, R. P. (R. P. T.), Hodson, J. (J.), Kamarajah, S. K. (S. K.), Griffiths, E. A. (E. A.), Singh, P. (P.), Alderson, D. (D.), Bundred, J. (J.), Gossage, J. (J.), Jefferies, B. (B.), McKay, S. (S.), Mohamed, I. (I), Nepogodiev, D. (D.), Siaw-Acheampong, K. (K.), van Hillegersberg, R. (R.), Vohra, R. (R.), Wanigasooriya, K. (K.), Whitehouse, T. (T.), Gjata, A. (A.), Moreno, J. I. (J., I), Takeda, F. R. (F. R.), Kidane, B. (B.), Castro, R. G. (R. Guevara), Harustiak, T. (T.), Bekele, A. (A.), Kechagias, A. (A.), Gockel, I. (I), Kennedy, A. (A.), Da Roit, A. (A.), Bagajevas, A. (A.), Azagra, J. S. (J. S.), Mahendran, H. A. (H. A.), Mejia-Fernandez, L. (L.), Wijnhoven, B. P. (B. P. L.), El Kafsi, J. (J.), Sayyed, R. H. (R. H.), Sousa, M. (M.), Sampaio, A. S. (A. S.), Negoi, I. (I), Blanco, R. (R.), Wallner, B. (B.), Schneider, P. M. (P. M.), Hsu, P. K. (P. K.), Isik, A. (A.), Gananadha, S. (S.), Wills, V. (V), Devadas, M. (M.), Duong, C. (C.), Talbot, M. (M.), Hii, M. W. (M. W.), Jacobs, R. (R.), Andreollo, N. A. (N. A.), Johnston, B. (B.), Darling, G. (G.), Isaza-Restrepo, A. (A.), Rosero, G. (G.), Arias-Amezquita, F. (F.), Raptis, D. (D.), Gaedcke, J. (J.), Reim, D. (D.), Izbicki, J. (J.), Egberts, J. H. (J. H.), Dikinis, S. (S.), Kjaer, D. W. (D. W.), Larsen, M. H. (M. H.), Achiam, M. P. (M. P.), Saarnio, J. (J.), Theodorou, D. (D.), Liakakos, T. (T.), Korkolis, D. P. (D. P.), Robb, W. B. (W. B.), Collins, C. (C.), Murphy, T. (T.), Reynolds, J. (J.), Tonini, V. (V), Migliore, M. (M.), Bonavina, L. (L.), Valmasoni, M. (M.), Bardini, R. (R.), Weindelmayer, J. (J.), Terashima, M. (M.), White, R. E. (R. E.), Alghunaim, E. (E.), Elhadi, M. (M.), Leon-Takahashi, A. M. (A. M.), Medina-Franco, H. (H.), Lau, P. C. (P. C.), Okonta, K. E. (K. E.), Heisterkamp, J. (J.), Rosman, C. (C.), Beban, G. (G.), Babor, R. (R.), Gordon, A. (A.), Rossaak, J. I. (J., I), Pal, K. M. (K. M., I), Qureshi, A. U. (A. U.), Naqi, S. A. (S. A.), Syed, A. A. (A. A.), Barbosa, J. (J.), Vicente, C. S. (C. S.), Leite, J. (J.), Freire, J. (J.), Casaca, R. (R.), Costa, R. C. (R. C. T.), Scurtu, R. R. (R. R.), Mogoanta, S. S. (S. S.), Bolca, C. (C.), Constantinoiu, S. (S.), Sekhniaidze, D. (D.), So, J. B. (J. B. Y.), Gacvski, G. (G.), Loureiro, C. (C.), Pera, M. (M.), Bianchi, A. (A.), Gijon, M. M. (M. Moreno), Fernandez, J. M. (J. Martin), Carrera, M. S. (M. S. Trugeda), Vallve-Bernal, M. (M.), Pascual, M. A. (M. A. Citores), Elmahi, S. (S.), Halldestam, I. (I), Hedberg, J. (J.), Monig, S. (S.), Gutknecht, S. (S.), Tez, M. (M.), Guner, A. (A.), Tirnaksiz, T. B. (T. B.), Colak, E. (E.), Sevinc, B. (B.), Hindmarsh, A. (A.), Khan, I. (I), Khoo, D. (D.), Byrom, R. (R.), Gokhale, J. (J.), Wilkerson, P. (P.), Jain, P. (P.), Chan, D. (D.), Robertson, K. (K.), Iftikhar, S. (S.), Skipworth, R. (R.), Forshaw, M. (M.), Higgs, S. (S.), Nijjar, R. (R.), Viswanath, Y. K. (Y. K. S.), Turner, P. (P.), Dexter, S. (S.), Boddy, A. (A.), Allum, W. H. (W. H.), Oglesby, S. (S.), Cheong, E. (E.), Beardsmore, D. (D.), Maynard, N. (N.), Berrisford, R. (R.), Mercer, S. (S.), Puig, S. (S.), Melhado, R. (R.), Kelty, C. (C.), Underwood, T. (T.), Dawas, K. (K.), Lewis, W. (W.), Al-Bahrani, A. (A.), Bryce, G. (G.), Thomas, M. (M.), Arndt, A. T. (A. T.), Palazzo, F. (F.), Meguid, R. A. (R. A.), Fergusson, J. (J.), Beenen, E. (E.), Mosse, C. (C.), Salim, J. (J.), Cheah, S. (S.), Wright, T. (T.), Cerdeira, M. P. (M. P.), McQuillan, P. (P.), Richardson, M. (M.), Liem, H. (H.), Spillane, J. (J.), Yacob, M. (M.), Albadawi, F. (F.), Thorpe, T. (T.), Dingle, A. (A.), Cabalag, C. (C.), Loi, K. (K.), Fisher, O. M. (O. M.), Ward, S. (S.), Read, M. (M.), Johnson, M. (M.), Bassari, R. (R.), Bui, H. (H.), Cecconello, I. (I), Sallum, R. A. (R. A. A.), da Rocha, J. R. (J. R. M.), Lopes, L. R. (L. R.), Tercioti, V. J. (V., Jr.), Coelho, J. D. (J. D. S.), Ferrer, J. A. (J. A. P.), Buduhan, G. (G.), Tan, L. (L.), Srinathan, S. (S.), Shea, P. (P.), Yeung, J. (J.), Allison, F. (F.), Carroll, P. (P.), Vargas-Barato, F. (F.), Gonzalez, F. (F.), Ortega, J. (J.), Nino-Torres, L. (L.), Beltran-Garcia, T. C. (T. C.), Castilla, L. (L.), Pineda, M. (M.), Bastidas, A. (A.), Gomez-Mayorga, J. (J.), Cortes, N. (N.), Cetares, C. (C.), Caceres, S. (S.), Duarte, S. (S.), Pazdro, A. (A.), Snajdauf, M. (M.), Faltova, H. (H.), Sevcikova, M. (M.), Mortensen, P. B. (P. B.), Katballe, N. (N.), Ingemann, T. (T.), Morten, B. (B.), Kruhlikava, I. (I), Ainswort, A. P. (A. P.), Stilling, N. M. (N. M.), Eckardt, J. (J.), Holm, J. (J.), Thorsteinsson, M. (M.), Siemsen, M. (M.), Brandt, B. (B.), Nega, B. (B.), Teferra, E. (E.), Tizazu, A. (A.), Kauppila, J. S. (J. S.), Koivukangas, V. (V), Meriläinen, S. (S.), Gruetzmann, R. (R.), Krautz, C. (C.), Weber, G. (G.), Golcher, H. (H.), Emons, G. (G.), Azizian, A. (A.), Ebeling, M. (M.), Niebisch, S. (S.), Kreuser, N. (N.), Albanese, G. (G.), Hesse, J. (J.), Volovnik, L. (L.), Boecher, U. (U.), Reeh, M. (M.), Triantafyllou, S. (S.), Schizas, D. (D.), Michalinos, A. (A.), Baili, E. (E.), Mpoura, M. (M.), Charalabopoulos, A. (A.), Manatakis, D. K. (D. K.), Balalis, D. (D.), Bolger, J. (J.), Baban, C. (C.), Mastrosimone, A. (A.), McAnena, O. (O.), Quinn, A. (A.), Suilleabhain, C. B. (C. B. O.), Hennessy, M. M. (M. M.), Ivanovski, I. (I.), Khizer, H. (H.), Ravi, N. (N.), Donlon, N. (N.), Cervellera, M. (M.), Vaccari, S. (S.), Bianchini, S. (S.), Sartarelli, L. (L.), Asti, E. (E.), Bernardi, D. (D.), Merigliano, S. (S.), Provenzano, L. (L.), Scarpa, M. (M.), Saadeh, L. (L.), Salmaso, B. (B.), De Manzoni, G. (G.), Giacopuzzi, S. (S.), La Mendola, R. (R.), De Pasqual, C. A. (C. A.), Tsubosa, Y. (Y.), Niihara, M. (M.), Irino, T. (T.), Makuuchi, R. (R.), Ishii, K. (K.), Mwachiro, M. (M.), Fekadu, A. (A.), Odera, A. (A.), Mwachiro, E. (E.), AlShehab, D. (D.), Ahmed, H. A. (H. A.), Shebani, A. O. (A. O.), Elhadi, A. (A.), Elnagar, F. A. (F. A.), Elnagar, H. F. (H. F.), Makkai-Popa, S. T. (S. T.), Wong, L. F. (L. F.), Yunrong, T. (T.), Thanninalai, S. (S.), Aik, H. C. (H. C.), Soon, P. W. (P. W.), Huei, T. J. (T. J.), Basave, H. N. (H. N. L.), Cortes-Gonzalez, R. (R.), Lagarde, S. M. (S. M.), van Lanschot, J. J. (J. J. B.), Cords, C. (C.), Jansen, W. A. (W. A.), Martijnse, I. (I), Matthijsen, R. (R.), Bouwense, S. (S.), Klarenbeek, B. (B.), Verstegen, M. (M.), van Workum, F. (F.), Ruurda, J. P. (J. P.), van der Veen, A. (A.), van den Berg, J. W. (J. W.), Evenett, N. (N.), Johnston, P. (P.), Patel, R. (R.), MacCormick, A. (A.), Young, M. (M.), Smith, B. (B.), Ekwunife, C. (C.), Memon, A. H. (A. H.), Shaikh, K. (K.), Wajid, A. (A.), Khalil, N. (N.), Haris, M. (M.), Mirza, Z. U. (Z. U.), Qudus, S. B. (S. B. A.), Sarwar, M. Z. (M. Z.), Shehzadi, A. (A.), Raza, A. (A.), Jhanzaib, M. H. (M. H.), Farmanali, J. (J.), Zakir, Z. (Z.), Shakeel, O. (O.), Nasir, I. (I), Khattak, S. (S.), Baig, M. (M.), Noor, M. A. (M. A.), Ahmed, H. H. (H. H.), Naeem, A. (A.), Pinho, A. C. (A. C.), da Silva, R. (R.), Bernardes, A. (A.), Campos, J. C. (J. C.), Matos, H. (H.), Braga, T. (T.), Monteiro, C. (C.), Ramos, P. (P.), Cabral, F. (F.), Gomes, M. P. (M. P.), Martins, P. C. (P. C.), Correia, A. M. (A. M.), Videira, J. F. (J. F.), Ciuce, C. (C.), Drasovean, R. (R.), Apostu, R. (R.), Paitici, S. (S.), Racu, A. E. (A. E.), Obleaga, C. V. (C., V), Beuran, M. (M.), Stoica, B. (B.), Ciubotaru, C. (C.), Negoita, V. (V), Cordos, I. (I), Birla, R. D. (R. D.), Predescu, D. (D.), Hoara, P. A. (P. A.), Tomsa, R. (R.), Shneider, V. (V), Agasiev, M. (M.), Ganjara, I. (I), Gunjic, D. (D.), Veselinovic, M. (M.), Babic, T. (T.), Chin, T. S. (T. S.), Shabbir, A. (A.), Kim, G. (G.), Crnjac, A. (A.), Samo, H. (H.), del Val, I. D. (I. Diez), Leturio, S. (S.), Ramon, J. M. (J. M.), Dal Cero, M. (M.), Rifa, S. (S.), Rico, M. (M.), Pomar, A. P. (A. Pagan), Corcoles, J. A. (J. A. Martinez), Miravalles, J. L. (J. L. Rodicio), Pais, S. A. (S. A.), Turienzo, S. A. (S. A.), Alvarez, L. S. (L. S.), Campos, P. V. (P., V), Rendo, A. G. (A. G.), Garcia, S. S. (S. S.), Santos, E. P. (E. P. G.), Martinez, E. T. (E. T.), Diaz, M. J. (M. J. Fernandez), Alvarez, C. M. (C. Magadan), Martin, V. C. (V. Concepcion), Lopez, C. D. (C. Diaz), Rodrigo, A. R. (A. Rosat), Sanchez, L. E. (L. E. Perez), Cuadrado, M. B. (M. Bailon), Carrasco, C. T. (C. Tinoco), Bhojwani, E. C. (E. Choolani), Sanchez, D. P. (D. P.), Ahmed, M. E. (M. E.), Dzhendov, T. (T.), Lindberg, F. (F.), Rutegard, M. (M.), Sundbom, M. (M.), Mickael, C. (C.), Colucci, N. (N.), Schnider, A. (A.), Er, S. (S.), Kurnaz, E. (E.), Turkyilmaz, S. (S.), Turkyilmaz, A. (A.), Yildirim, R. (R.), Baki, B. E. (B. E.), Akkapulu, N. (N.), Karahan, O. (O.), Damburaci, N. (N.), Hardwick, R. (R.), Safranek, P. (P.), Sujendran, V. (V), Bennett, J. (J.), Afzal, Z. (Z.), Shrotri, M. (M.), Chan, B. (B.), Exarchou, K. (K.), Gilbert, T. (T.), Amalesh, T. (T.), Mukherjee, D. (D.), Mukherjee, S. (S.), Wiggins, T. H. (T. H.), Kennedy, R. (R.), McCain, S. (S.), Harris, A. (A.), Dobson, G. (G.), Davies, N. (N.), Wilson, I. (I), Mayo, D. (D.), Bennett, D. (D.), Young, R. (R.), Manby, P. (P.), Blencowe, N. (N.), Schiller, M. (M.), Byrne, B. (B.), Mitton, D. (D.), Wong, V. (V), Elshaer, A. (A.), Cowen, M. (M.), Menon, V. (V), Tan, L. C. (L. C.), McLaughlin, E. (E.), Koshy, R. (R.), Sharp, C. (C.), Brewer, H. (H.), Das, N. (N.), Cox, M. (M.), Al Khyatt, W. (W.), Worku, D. (D.), Iqbal, R. (R.), Walls, L. (L.), McGregor, R. (R.), Fullarton, G. (G.), Macdonald, A. (A.), MacKay, C. (C.), Craig, C. (C.), Dwerryhouse, S. (S.), Hornby, S. (S.), Jaunoo, S. (S.), Wadley, M. (M.), Baker, C. (C.), Saad, M. (M.), Kelly, M. (M.), Davies, A. (A.), Di Maggio, F. (F.), Mistry, P. (P.), Singhal, R. (R.), Tucker, O. (O.), Kapoulas, S. (S.), Powell-Brett, S. (S.), Davis, P. (P.), Bromley, G. (G.), Watson, L. (L.), Verma, R. (R.), Ward, J. (J.), Shetty, V. (V), Ball, C. (C.), Pursnani, K. (K.), Sarela, A. (A.), Ling, H. S. (H. Sue), Mehta, S. (S.), Hayden, J. (J.), To, N. (N.), Palser, T. (T.), Hunter, D. (D.), Supramaniam, K. (K.), Butt, Z. (Z.), Ahmed, A. (A.), Kumar, S. (S.), Chaudry, A. (A.), Moussa, O. (O.), Kordzadeh, A. (A.), Patil, P. (P.), Noaman, I. (I), Willem, J. (J.), Bouras, G. (G.), Evans, R. (R.), Singh, M. (M.), Warrilow, H. (H.), Ahmad, A. (A.), Tewari, N. (N.), Yanni, F. (F.), Couch, J. (J.), Theophilidou, E. (E.), Reilly, J. J. (J. J.), van Boxel, G. (G.), Akbari, K. (K.), Zanotti, D. (D.), Sgromo, B. (B.), Sanders, G. (G.), Wheatley, T. (T.), Ariyarathenam, A. (A.), Reece-Smith, A. (A.), Humphreys, L. (L.), Choh, C. (C.), Carter, N. (N.), Knight, B. (B.), Pucher, P. (P.), Athanasiou, A. (A.), Tan, B. (B.), Abdulrahman, M. (M.), Vickers, J. (J.), Akhtar, K. (K.), Chaparala, R. (R.), Brown, R. (R.), Alasmar, M. M. (M. M. A.), Ackroyd, R. (R.), Patel, K. (K.), Tamhankar, A. (A.), Wyman, A. (A.), Walker, R. (R.), Grace, B. (B.), Abbassi, N. (N.), Slim, N. (N.), Ioannidi, L. (L.), Blackshaw, G. (G.), Havard, T. (T.), Escofet, X. (X.), Powell, A. (A.), Owera, A. (A.), Rashid, F. (F.), Jambulingam, P. (P.), Padickakudi, J. (J.), Ben-Younes, H. (H.), McCormack, K. (K.), Makey, I. A. (I. A.), Karush, M. K. (M. K.), Seder, C. W. (C. W.), Liptay, M. J. (M. J.), Chmielewski, G. (G.), Rosato, E. L. (E. L.), Berger, A. C. (A. C.), Zheng, R. (R.), Okolo, E. (E.), Singh, A. (A.), Scott, C. D. (C. D.), Weyant, M. J. (M. J.), and Mitchell, J. D. (J. D.)
- Abstract
Background: The complexity of oesophageal surgery and the significant risk of morbidity necessitates that oesophagectomy is predominantly performed by a consultant surgeon, or a senior trainee under their supervision. The aim of this study was to determine the impact of trainee involvement in oesophagectomy on postoperative outcomes in an international multicentre setting. Methods: Data from the multicentre Oesophago-Gastric Anastomosis Study Group (OGAA) cohort study were analysed, which comprised prospectively collected data from patients undergoing oesophagectomy for oesophageal cancer between April 2018 and December 2018. Procedures were grouped by the level of trainee involvement, and univariable and multivariable analyses were performed to compare patient outcomes across groups. Results: Of 2232 oesophagectomies from 137 centres in 41 countries, trainees were involved in 29.1 per cent of them (n = 650), performing only the abdominal phase in 230, only the chest and/or neck phases in 130, and all phases in 315 procedures. For procedures with a chest anastomosis, those with trainee involvement had similar 90-day mortality, complication and reoperation rates to consultant-performed oesophagectomies (P = 0.451, P = 0.318, and P = 0.382, respectively), while anastomotic leak rates were significantly lower in the trainee groups (P = 0.030). Procedures with a neck anastomosis had equivalent complication, anastomotic leak, and reoperation rates (P = 0.150, P = 0.430, and P = 0.632, respectively) in trainee-involved versus consultant-performed oesophagectomies, with significantly lower 90-day mortality in the trainee groups (P = 0.005). Conclusions: Trainee involvement was not found to be associated with significantly inferior postoperative outcomes for selected patients undergoing oesophagectomy. The results support continued supervised trainee involvement in oesophageal cancer surgery.
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- 2021
44. A Simplified Technique for Translaryngeal Tracheostomy (TLT). A Preliminary Report
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Katsaragakis, S., Theodorou, D., Drimousis, P., Stamou, K. M., Koutras, A., Kapralou, A., and Bramis, J.
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- 2007
- Full Text
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45. Enhanced recovery pathways vs standard care pathways in esophageal cancer surgery: systematic review and meta-analysis
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Triantafyllou, T. Olson, M.T. Theodorou, D. Schizas, D. Singhal, S.
- Abstract
Enhanced recovery after surgery (ERAS) protocols vs standard care pathways after esophagectomy for malignancy have gained wide popularity among surgeons. However, the current literature is still lacking level-I evidence to show a clear superiority of one approach. The present study is a detailed systematic review and meta-analysis of the published trials. A systematic review of literature databases was conducted for randomized controlled trials (RCTs) and non-randomized, prospective, comparative studies between January 1990 and September 2019, comparing ERAS pathway group with standard care for esophageal resection for esophageal cancer. Mean difference (MD) for continuous variables and odds ratio (OR) or risk difference (RD) for dichotomous variables with 95% confidence interval (CI) were used. Between-study heterogeneity was evaluated. Eight studies with a total of 1133 patients were included. Hospital stay [Standard mean difference (Std. MD) = − 1.92, 95% CI − 2.78, − 1.06, P < 0.0001], overall morbidity (OR 0.68, CI 0.49, 0.96, P = 0.03), pulmonary complications (OR 0.45, CI 0.31, 0.65, P < 0.0001), anastomotic leak rate (OR 0.37, CI 0.18, 0.74, P = 0.005), time to first flatus and defecation (Std. MD = -5.01, CI − 9.53, − 0.49, P = 0.03), (Std. MD = − 1.36, CI − 1.78, − 0.94, P < 0.00001) and total hospital cost (Std. MD = − 1.62, CI − 2.24, − 1.01, P < 0.00001) favored the ERAS group. Patients who undergo ERAS have a clear benefit over the standard care protocol. However, existing protocols in different centers are followed by great variability, while the evaluated parameters suffer from significant heterogeneity. A well-formulated, standardized protocol should be standard-of-care at all centers. © 2020, The Japan Esophageal Society.
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- 2020
46. Esophageal cancer: Challenges, concerns, and recommendations for management amidst the COVID-19 pandemic
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Triantafyllou, T. Olson, M.T. Theodorou, D. Zografos, G. Singhal, S.
- Abstract
Since December 2019, the outbreak of coronavirus disease 2019 (COVID-19) has rapidly spread worldwide, raising great concern, particularly in immunosuppressed cancer patients. The pandemic situation remains extremely dynamic, which necessitates proactive management decisions from oncologists and oncologic surgeons in effort to mitigate the risk of both SARS-CoV-2 infection and cancer metastasis. Esophageal cancer, in particular, is one of the deadliest types of malignancy worldwide, reflecting both aggressive biology and a lack of adequate treatment. Several challenges and concerns regarding the management of esophageal cancer have been raised in light of the ongoing viral pandemic. The primary aim of this review is to summarize the salient evidence for recommendations and optimal treatment strategies for patients with esophageal cancer amidst the COVID-19 pandemic. © 2020 Hellenic Society of Gastroenterology.
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- 2020
47. Natural history of Achalasia captured
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Larentzakis, A. Triantafyllou, T. Theodorou, D.
- Subjects
otorhinolaryngologic diseases - Abstract
achalasia of the esophagus is a primary motility disorder involving the smooth muscle layer of the esophagus and the lower esophageal sphincter. Despite the use of novel diagnostic tools such as high-resolution manometry, the disease may remain misdiagnosed for several years. Even after diagnosis, if left untreated, the natural history of achalasia leads to deterioration of both clinical and radiologic image. a female patient complained of dysphagia and weight loss since the age of 20, but it was not until the age of 40 that she agreed to undergo the complete diagnostic workup, which disclosed achalasia of the esophagus. This case report is a presentation of the evolution of the disease after medical, endoscopic and, finally, surgical treatment several years after the initial diagnosis. Laparoscopic myotomy and fundoplication resulted in improvement of her clinical condition. Treatment options of achalasia consist of conservative, endoscopic, and surgical techniques. Laparoscopic myotomy achieves the optimal long-term outcome as it is considered to be up to 90% successful. although peroral endoscopic myotomy seems to be a promising approach, the literature still lacks long-term results especially regarding postoperative reflux rates. All approaches are thought to be palliative aiming to reduce the severity of symptoms. in the present case we present the natural history of a case diagnosed with achalasia at a young age that gradually underwent all treatment options until the surgical approach improved her symptoms several years after initial diagnosis. © 2019 EDIZIONI MINERVA MEDICA
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- 2020
48. Esophageal melanoma: A systematic review and exploratory recurrence and survival analysis
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Schizas, D. Mylonas, K.S. Bagias, G. Mastoraki, A. Ioannidi, M. Kanavidis, P. Hasemaki, N. Karavokyros, I. Theodorou, D. Liakakos, T.
- Abstract
Esophageal melanoma is a rare and poorly described malignancy. We sought to review all available data on the clinicopathological features, management options, and outcomes of patients with esophageal melanoma to guide clinicians working to treat these uncommon tumors. A systematic literature search of the PubMed, Embase, and Cochrane databases was performed. Exploratory recurrence and survival analyses were performed using previously-validated pooled Cox and logistic regression techniques for case reports and case series. Quality assessment of included studies was performed using the tools developed by the Joanna Briggs and the National Heart, Lung, and Blood Institutes. Fifty-nine studies were reviewed. A total of 93 patients with esophageal melanoma were identified. The mean patient age was 61.2 ± 10.6 years. Esophageal melanoma usually developed at the lower esophagus (48.4%). 90.3% of the patients were symptomatic at presentation, with dysphagia being the most common symptom (72%). Esophagectomy was performed in 91.4% of the patients. Postoperatively, 14 patients (15.1%) received adjuvant chemotherapy. Tumor recurrence was seen in 37 patients (39.8%). The median time to recurrence was 6 months. Disease-specific mortality was 43%. All-cause mortality was 46.1%. On multivariable Cox regression, older patient age (hazard ratio [HR] = 0.91, P = 0.008) and higher Melan-A expression (HR = 0.21; P = 0.029) were associated with a significantly lower risk of mortality. Higher S100 levels (HR = 37.4; P = 0.001) were predictive of poor survival. On logistic regression, large, ulcerated, lower esophageal tumors were significantly more likely to recur (P = 0.018, P = 0.013, and P = 0.027 respectively). Esophageal melanoma is a rare malignancy that tends to present with dysphagia. Most surgically-treated patients undergo esophagectomy. Large, ulcerated, lower esophageal lesions recur more frequently. Immunohistochemistry provides prognostic information regarding survival. © 2019 The Author(s) 2019. Published by Oxford University Press on behalf of International Society for Diseases of the Esophagus. All rights reserved.
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- 2020
49. COVID-19 vaccine-related myositis
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Theodorou, D J, primary, Theodorou, S J, additional, Axiotis, A, additional, Gianniki, M, additional, and Tsifetaki, N, additional
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- 2021
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50. Quantitative Computed Tomography in the Evaluation of Spinal Osteoporosis Following Spinal Cord Injury
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Liu, C. C., Theodorou, D. J., Theodorou, S. J., Andre, M. P., Sartoris, D. J., Szollar, S. M., Martin, E. M., and Deftos, L. J.
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- 2000
- Full Text
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