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13. Global Impact of COVID-19 on Stroke Care and IV Thrombolysis

Author

Nogueira, Raul, Qureshi, Muhammad, Abdalkader, Mohamad, Martins, Sheila Ouriques, Yamagami, Hiroshi, Qiu, Zhongming, Mansour, Ossama Yassin, Sathya, Anvitha, Czlonkowska, Anna, Tsivgoulis, Georgios, Aguiar de Sousa, Diana, Demeestere, Jelle, Mikulik, Robert, Vanacker, Peter, Siegler, James, Kõrv, Janika, Biller, Jose, Liang, Conrad, Sangha, Navdeep, Zha, Alicia, Czap, Alexandra, Holmstedt, Christine Anne, Turan, Tanya, Ntaios, George, Malhotra, Konark, Tayal, Ashis, Loochtan, Aaron, Ranta, Annamarei, Mistry, Eva, Alexandrov, Anne, Huang, David, Yaghi, Shadi, Raz, Eytan, Sheth, Sunil, Mohammaden, Mahmoud, Frankel, Michael, Bila Lamou, Eric Guemekane, Aref, Hany, Elbassiouny, Ahmed, Hassan, Farouk, Menecie, Tarek, Mustafa, Wessam, Shokri, Hossam, Roushdy, Tamer, Sarfo, Fred, Alabi, Tolulope Oyetunde, Arabambi, Babawale, Nwazor, Ernest, Sunmonu, Taofiki Ajao, Wahab, Kolawole, Yaria, Joseph, Mohammed, Haytham Hussein, Adebayo, Philip, Riahi, Anis, Sassi, Samia Ben, Gwaunza, Lenon, Ngwende, Gift Wilson, Sahakyan, David, Rahman, Aminur, Ai, Zhibing, Bai, Fanghui, Duan, Zhenhui, Hao, Yonggang, Huang, Wenguo, Li, Guangwen, Li, Wei, Liu, Ganzhe, Luo, Jun, Shang, Xianjin, Sui, Yi, Tian, Ling, Wen, Hongbin, Wu, Bo, Yan, Yuying, Yuan, Zhengzhou, Zhang, Hao, Zhang, Jun, Zhao, Wenlong, Zi, Wenjie, Leung, Thomas, Chugh, Chandril, Huded, Vikram, Menon, Bindu, Pandian, Jeyaraj Durai, Sylaja, Pn, Usman, Fritz Sumantri, Farhoudi, Mehdi, Hokmabadi, Elyar Sadeghi, Horev, Anat, Reznik, Anna, Sivan Hoffmann, Rotem, Ohara, Nobuyuki, Sakai, Nobuyuki, Watanabe, Daisuke, Yamamoto, Ryoo, Doijiri, Ryosuke, Tokuda, Naoki, Yamada, Takehiro, Terasaki, Tadashi, Yazawa, Yukako, Uwatoko, Takeshi, Dembo, Tomohisa, Shimizu, Hisao, Sugiura, Yuri, Miyashita, Fumio, Fukuda, Hiroki, Miyake, Kosuke, Shimbo, Junsuke, Sugimura, Yusuke, Yagita, Yoshiki, Takenobu, Yohei, Matsumaru, Yuji, Yamada, Satoshi, Kono, Ryuhei, Kanamaru, Takuya, Yamazaki, Hidekazu, Sakaguchi, Manabu, Todo, Kenichi, Yamamoto, Nobuaki, Sonoda, Kazutaka, Yoshida, Tomoko, Hashimoto, Hiroyuki, Nakahara, Ichiro, Kondybayeva, Aida, Faizullina, Kamila, Kamenova, Saltanat, Zhanuzakov, Murat, Baek, Jang-Hyun, Hwang, Yangha, Lee, Jin Soo, Lee, Si Baek, Moon, Jusun, Park, Hyungjong, Seo, Jung Hwa, Seo, Kwon-Duk, Sohn, Sung Il, Young, Chang Jun, Ahdab, Rechdi, Wan Zaidi, Wan Asyraf, Aziz, Zariah Abdul, Basri, Hamidon Bin, Chung, Law Wan, Ibrahim, Aznita Binti, Ibrahim, Khairul Azmi, Looi, Irene, Tan, Wee Yong, Yahya, Nafisah Wan, Groppa, Stanislav, Leahu, Pavel, Al Hashmi, Amal, Imam, Yahia Zakaria, Akhtar, Naveed, Pineda-Franks, Maria Carissa, Co, Christian Oliver, Kandyba, Dmitriy, Alhazzani, Adel, Al-Jehani, Hosam, Tham, Carol Huilian, Mamauag, Marlie Jane, Venketasubramanian, Narayanaswamy, Chen, Chih-Hao, Tang, Sung-Chun, Churojana, Anchalee, Akil, Esref, Aykaç, Özlem, Ozdemir, Atilla Ozcan, Giray, Semih, Hussain, Syed Irteza, John, Seby, Le Vu, Huynh, Tran, Anh Duc, Nguyen, Huy Hoang, Nhu Pham, Thong, Nguyen, Thang Huy, Nguyen, Trung Quoc, Gattringer, Thomas, Enzinger, Christian, Killer-Oberpfalzer, Monika, Bellante, Flavio, de Blauwe, Sofie, Vanhooren, Geert, de Raedt, Sylvie, Dusart, Anne, Lemmens, Robin, Ligot, Noemie, Pierre Rutgers, Matthieu, Yperzeele, Laetitia, Alexiev, Filip, Sakelarova, Teodora, Bedeković, Marina Roje, Budincevic, Hrvoje, Cindric, Igor, Hucika, Zlatko, Ozretic, David, Saric, Majda Seferovic, Pfeifer, František, Karpowic, Igor, Cernik, David, Sramek, Martin, Skoda, Miroslav, Hlavacova, Helena, Klecka, Lukas, Koutny, Martin, Vaclavik, Daniel, Skoda, Ondrej, Fiksa, Jan, Hanelova, Katerina, Nevsimalova, Miroslava, Rezek, Robert, Prochazka, Petr, Krejstova, Gabriela, Neumann, Jiri, Vachova, Marta, Brzezanski, Henryk, Hlinovsky, David, Tenora, Dusan, Jura, Rene, Jurák, Lubomír, Novak, Jan, Novak, Ales, Topinka, Zdenek, Fibrich, Petr, Sobolova, Helena, Volny, Ondrej, Krarup Christensen, Hanne, Drenck, Nicolas, Klingenberg Iversen, Helle, Simonsen, Claus, Truelsen, Thomas Clement, Wienecke, Troels, Vibo, Riina, Gross-Paju, Katrin, Toomsoo, Toomas, Antsov, Katrin, Caparros, Francois, Cordonnier, Charlotte, Dan, Maria, Faucheux, Jean-Marc, Mechtouff, Laura, Eker, Omer, Lesaine, Emilie, Ondze, Basile, Peres, Roxane, Pico, Fernando, Piotin, Michel, Pop, Raoul, Rouanet, Francois, Gubeladze, Tatuli, Khinikadze, Mirza, Lobjanidze, Nino, Tsiskaridze, Alexander, Nagel, Simon, Ringleb, Peter Arthur, Rosenkranz, Michael, Schmidt, Holger, Sedghi, Annahita, Siepmann, Timo, Szabo, Kristina, Thomalla, Götz, Palaiodimou, Lina, Sagris, Dimitrios, Kargiotis, Odysseas, Klivenyi, Peter, Szapary, Laszlo, Tarkanyi, Gabor, Adami, Alessandro, Bandini, Fabio, Calabresi, Paolo, Frisullo, Giovanni, Renieri, Leonardo, Sangalli, Davide, Pirson, Anne, Uyttenboogaart, Maarten, van den Wijngaard, Ido, Kristoffersen, Espen Saxhaug, Brola, Waldemar, Fudala, Małgorzata, Horoch-Lyszczarek, Ewa, Karlinski, Michal, Kazmierski, Radoslaw, Kram, Pawel, Rogoziewicz, Marcin, Kaczorowski, Rafal, Luchowski, Piotr, Sienkiewicz-Jarosz, Halina, Sobolewski, Piotr, Fryze, Waldemar, Wisniewska, Anna, Wiszniewska, Malgorzata, Ferreira, Patricia, Ferreira, Paulo, Fonseca, Luisa, Marto, João Pedro, Pinho E Melo, Teresa, Nunes, Ana Paiva, Rodrigues, Miguel, Tedim Cruz, Vítor, Falup-Pecurariu, Cristian, Krastev, Georgi, Mako, Miroslav, de Leciñana, María Alonso, Arenillas, Juan, Ayo-Martin, Oscar, Cruz Culebras, Antonio, Tejedor, Exuperio Diez, Montaner, Joan, Pérez-Sánchez, Soledad, Tola Arribas, Miguel Angel, Rodriguez Vasquez, Alejandro, Mayza, Michael, Bernava, Gianmarco, Brehm, Alex, Machi, Paolo, Fischer, Urs, Gralla, Jan, Michel, Patrik, Psychogios, Marios-Nikos, Strambo, Davide, Banerjee, Soma, Krishnan, Kailash, Kwan, Joseph, Butt, Asif, Catanese, Luciana, Demchuk, Andrew, Field, Thalia, Haynes, Jennifer, Hill, Michael, Khosravani, Houman, Mackey, Ariane, Pikula, Aleksandra, Saposnik, Gustavo, Scott, Courtney Anne, Shoamanesh, Ashkan, Shuaib, Ashfaq, Yip, Samuel, Barboza, Miguel, Barrientos, Jose Domingo, Portillo Rivera, Ligia Ibeth, Gongora-Rivera, Fernando, Novarro-Escudero, Nelson, Blanco, Anmylene, Abraham, Michael, Alsbrook, Diana, Altschul, Dorothea, Alvarado-Ortiz, Anthony, Bach, Ivo, Badruddin, Aamir, Barazangi, Nobl, Brereton, Charmaine, Castonguay, Alicia, Chaturvedi, Seemant, Chaudry, Saqib, Choe, Hana, Choi, Jae, Dharmadhikari, Sushrut, Desai, Kinjal, Devlin, Thomas, Doss, Vinodh, Edgell, Randall, Etherton, Mark, Farooqui, Mudassir, Frei, Don, Gandhi, Dheeraj, Grigoryan, Mikayel, Gupta, Rishi, Hassan, Ameer, Helenius, Johanna, Kaliaev, Artem, Kaushal, Ritesh, Khandelwal, Priyank, Khawaja, Ayaz, Khoury, Naim, Kim, Benny, Kleindorfer, Dawn, Koyfman, Feliks, Lee, Vivien, Leung, Lester, Linares, Guillermo, Linfante, Italo, Lutsep, Helmi, Macdougall, Lisa, Male, Shailesh, Malik, Amer, Masoud, Hesham, Mcdermott, Molly, Mehta, Brijesh, Min, Jiangyong, Mittal, Manoj, Morris, Jane, Multani, Sumeet, Nahab, Fadi, Nalleballe, Krishna, Nguyen, Claude, Novakovic-White, Roberta, Ortega-Gutierrez, Santiago, Rahangdale, Rahul, Ramakrishnan, Pankajavalli, Romero, Jose Rafael, Rost, Natalia, Rothstein, Aaron, Ruland, Sean, Shah, Ruchir, Sharma, Malveeka, Silver, Brian, Simmons, Marc, Singh, Abhishek, Starosciak, Amy, Strasser, Sheryl, Szeder, Viktor, Teleb, Mohamed, Tsai, Jenny, Voetsch, Barbara, Balaguera, Oscar, Pujol Lereis, Virginia, Luraschi, Adriana, Almeida, Marcele Schettini, Cardoso, Fabricio Buchdid, Conforto, Adriana, de Deus Silva, Leonardo, Varrone Giacomini, Luidia, Oliveira Lima, Fabricio, Longo, Alexandre, Magalhães, Pedro, Martins, Rodrigo Targa, Mont'Alverne, Francisco, Mora Cuervo, Daissy Liliana, Costa Rebello, Leticia, Valler, Lenise, Zetola, Viviane Flumignan, Lavados, Pablo, Navia, Victor, Olavarría, Verónica, Almeida Toro, Juan Manuel, Amaya, Pablo Felipe Ricardo, Bayona, Hernan, Corredor, Angel, Rivera Ordonez, Carlos Eduardo, Mantilla Barbosa, Diana Katherine, Lara, Osvaldo, Patiño, Mauricio, Diaz Escobar, Luis Fernando, Dejesus Melgarejo Fariña, Donoband Edson, Cardozo Villamayor, Analia, Zelaya Zarza, Adolfo Javier, Barrientos Iman, Danny Moises, Rodriguez Kadota, Liliana, Campbell, Bruce, Hankey, Graeme, Hair, Casey, Kleinig, Timothy, Ma, Alice, Tomazini Martins, Rodrigo, Sahathevan, Ramesh, Thijs, Vincent, Salazar, Daniel, Yuan-Hao Wu, Teddy, Haussen, Diogo, Liebeskind, David, Yavagal, Dileep, Jovin, Tudor, Zaidat, Osama, Nguyen, Thanh, Magalhães, Pedro S.C., Emory University School of Medicine, Emory University [Atlanta, GA], Boston University School of Medicine (BUSM), Boston University [Boston] (BU), Lille Neurosciences & Cognition - U 1172 (LilNCog), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Max Super Speciality Hospital -Saket [New Delhi, Inde] (Max Saket), Dupuis, Christine, Lille Neurosciences & Cognition - U 1172 (LilNCog (ex-JPARC)), and Repositório da Universidade de Lisboa

Subjects
medicine.medical_specialty, MESH: Pandemics, HSJ NEU, Cross-sectional study, medicine.medical_treatment, [SDV]Life Sciences [q-bio], SVIN COVID-19 Global Stroke Registry, MESH: Hospitalization, 030204 cardiovascular system & hematology, Article, MESH: Stroke, COVID-19, cross-sectional studies, hospitalization, humans, pandemics, retrospective studies, SARS-CoV-2, stroke, 03 medical and health sciences, 0302 clinical medicine, MESH: Cross-Sectional Studies, Pandemic, Medicine, Humans, MESH: COVID-19, Thrombolytic Therapy, MESH: SARS-CoV-2, Stroke, Pandemics, Retrospective Studies, MESH: Thrombolytic Therapy, Rehabilitation, MESH: Humans, business.industry, Retrospective cohort study, MESH: Retrospective Studies, medicine.disease, Thrombolysis, Confidence interval, 3. Good health, Hospitalization, [SDV] Life Sciences [q-bio], Clinical research, Cross-Sectional Studies, Emergency medicine, Observational study, Neurology (clinical), business, 030217 neurology & neurosurgery
Abstract

© 2021 American Academy of Neurology, Objective: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods. Methods: We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases. Results: There were 91,373 stroke admissions in the 4 months immediately before compared to 80,894 admissions during the pandemic months, representing an 11.5% (95% confidence interval [CI] -11.7 to -11.3, p < 0.0001) decline. There were 13,334 IVT therapies in the 4 months preceding compared to 11,570 procedures during the pandemic, representing a 13.2% (95% CI -13.8 to -12.7, p < 0.0001) drop. Interfacility IVT transfers decreased from 1,337 to 1,178, or an 11.9% decrease (95% CI -13.7 to -10.3, p = 0.001). Recovery of stroke hospitalization volume (9.5%, 95% CI 9.2-9.8, p < 0.0001) was noted over the 2 later (May, June) vs the 2 earlier (March, April) pandemic months. There was a 1.48% stroke rate across 119,967 COVID-19 hospitalizations. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was noted in 3.3% (1,722/52,026) of all stroke admissions. Conclusions: The COVID-19 pandemic was associated with a global decline in the volume of stroke hospitalizations, IVT, and interfacility IVT transfers. Primary stroke centers and centers with higher COVID-19 inpatient volumes experienced steeper declines. Recovery of stroke hospitalization was noted in the later pandemic months.

Published
2021

15. Global Impact of COVID-19 on Stroke Care and Intravenous Thrombolysis

Author

Nogueira, Raul G, Qureshi, Muhammed M, Abdalkader, Mohamad, Martins, Sheila Ouriques, Yamagami, Hiroshi, Qiu, Zhongming, Mansour, Ossama Yassin, Sathya, Anvitha, Czlonkowska, Anna, Tsivgoulis, Georgios, Aguiar de Sousa, Diana, Demeestere, Jelle, Mikulik, Robert, Vanacker, Peter, Siegler, James E, Kõrv, Janika, Biller, Jose, Liang, Conrad W, Sangha, Navdeep S, Zha, Alicia M, Czap, Alexandra L, Holmstedt, Christine Anne, Turan, Tanya N, Ntaios, George, Malhotra, Konark, Tayal, Ashis, Loochtan, Aaron, Ranta, Annamarei, Mistry, Eva A, Alexandrov, Anne W, Huang, David Y, Yaghi, Shadi, Raz, Eytan, Sheth, Sunil A, Mohammaden, Mahmoud H, Frankel, Michael, Bila Lamou, Eric Guemekane, Aref, Hany M, Elbassiouny, Ahmed, Hassan, Farouk, Menecie, Tarek, Mustafa, Wessam, Shokri, Hossam M, Roushdy, Tamer, Sarfo, Fred S, Alabi, Tolulope Oyetunde, Arabambi, Babawale, Nwazor, Ernest O, Sunmonu, Taofiki Ajao, Wahab, Kolawole, Yaria, Joseph, Mohammed, Haytham Hussein, Adebayo, Philip B, Riahi, Anis D, Ben Sassi, Samia, Gwaunza, Lenon, Ngwende, Gift Wilson, Sahakyan, David, Rahman, Aminur, Ai, Zhibing, Bai, Fanghui, Duan, Zhenhui, Hao, Yonggang, Huang, Wenguo, Li, Guangwen, Li, Wei, Liu, Ganzhe, Luo, Jun, Shang, Xianjin, Sui, Yi, Tian, Ling, Wen, Hongbin, Wu, Bo, Yan, Yuying, Yuan, Zhengzhou, Zhang, Hao, Zhang, Jun, Zhao, Wenlong, Zi, Wenjie, Leung, Thomas W, Chugh, Chandril, Huded, Vikram, Menon, Bindu, Pandian, Jeyaraj Durai, Sylaja, P N, Usman, Fritz Sumantri, Farhoudi, Mehdi, Hokmabadi, Elyar Sadeghi, Horev, Anat, Reznik, Anna, Hoffmann, Rotem Sivan, Ohara, Nobuyuki, Sakai, Nobuyuki, Watanabe, Daisuke, Yamamoto, Ryoo, Doijiri, Ryosuke, Tokuda, Naoki, Yamada, Takehiro, Terasaki, Tadashi, Yazawa, Yukako, Uwatoko, Takeshi, Dembo, Tomohisa, Shimizu, Hisao, Sugiura, Yuri, Miyashita, Fumio, Fukuda, Hiroki, Miyake, Kosuke, Shimbo, Junsuke, Sugimura, Yusuke, Yagita, Yoshiki, Takenobu, Yohei, Matsumaru, Yuji, Yamada, Satoshi, Kono, Ryuhei, Kanamaru, Takuya, Yamazaki, Hidekazu, Sakaguchi, Manabu, Todo, Kenichi, Yamamoto, Nobuaki, Sonoda, Kazutaka, Yoshida, Tomoko, Hashimoto, Hiroyuki, Nakahara, Ichiro, Kondybayeva, Aida, Faizullina, Kamila, Kamenova, Saltanat, Zhanuzakov, Murat, Baek, Jang-Hyun, Hwang, Yangha, Lee, Jin Soo, Lee, Si Baek, Moon, Jusun, Park, Hyungjong, Seo, Jung Hwa, Seo, Kwon-Duk, Sohn, Sung Il, Young, Chang Jun, Ahdab, Rechdi, Wan Zaidi, Wan Asyraf, Aziz, Zariah Abdul, Basri, Hamidon Bin, Chung, Law Wan, Ibrahim, Aznita Binti, Ibrahim, Khairul Azmi, Looi, Irene, Tan, Wee Yong, Yahya, Nafisah Wan, Groppa, Stanislav, Leahu, Pavel, Al Hashmi, Amal M, Imam, Yahia Zakaria, Akhtar, Naveed, Pineda-Franks, Maria Carissa, Co, Christian Oliver, Kandyba, Dmitriy, Alhazzani, Adel, Al-Jehani, Hosam, Tham, Carol Huilian, Mamauag, Marlie Jane, Venketasubramanian, Narayanaswamy, Chen, Chih-Hao, Tang, Sung-Chun, Churojana, Anchalee, Akil, Esref, Aykaç, Ozlem, Ozdemir, Atilla Ozcan, Giray, Semih, Hussain, Syed Irteza, John, Seby, Le Vu, Huynh, Tran, Anh Duc, Nguyen, Huy Hoang, Pham, Thong Nhu, Nguyen, Thang Huy, Nguyen, Trung Quoc, Gattringer, Thomas, Enzinger, Christian, Killer-Oberpfalzer, Monika, Bellante, Flavio, De Blauwe, Sofie, Vanhooren, Geert, De Raedt, Sylvie, Dusart, Anne, Lemmens, Robin, Ligot, Noemie, Rutgers, Matthieu Pierre, Yperzeele, Laetitia, Alexiev, Filip, Sakelarova, Teodora, Bedeković, Marina Roje, Budincevic, Hrvoje, Cindrić, Igor, Hucika, Zlatko, Ozretic, David, Saric, Majda Seferovic, Pfeifer, Frantiek, Karpowic, Igor, Cernik, David, Sramek, Martin, Skoda, Miroslav, Hlavacova, Helena, Klecka, Lukas, Koutny, Martin, Vaclavik, Daniel, Skoda, Ondrej, Fiksa, Jan, Hanelova, Katerina, Nevsimalova, Miroslava, Rezek, Robert, Prochazka, Petr, Krejstova, Gabriela, Neumann, Jiri, Vachova, Marta, Brzezanski, Henryk, Hlinovsky, David, Tenora, Dusan, Jura, Rene, Jurák, Lubomír, Novak, Jan, Novak, Ales, Topinka, Zdenek, Fibrich, Petr, Sobolova, Helena, Volny, Ondrej, Christensen, Hanne Krarup, Drenck, Nicolas, Iversen, Helle Klingenberg, Simonsen, Claus Z, Truelsen, Thomas Clement, Wienecke, Troels, Vibo, Riina, Gross-Paju, Katrin, Toomsoo, Toomas, Antsov, Katrin, Caparros, Francois, Cordonnier, Charlotte, Dan, Maria, Faucheux, Jean-Marc, Mechtouff, Laura, Eker, Omer, Lesaine, Emilie, Ondze, Basile, Peres, Roxane, Pico, Fernando, Piotin, Michel, Pop, Raoul, Rouanet, Francois, Gubeladze, Tatuli, Khinikadze, Mirza, Lobjanidze, Nino, Tsikaridze, Alexander, Nagel, Simon, Ringleb, Peter Arthur, Rosenkranz, Michael, Schmidt, Holger, Sedghi, Annahita, Siepmann, Timo, Szabo, Kristina, Thomalla, Götz, Palaiodimou, Lina, Sagris, Dimitrios, Kargiotis, Odysseas, Klivenyi, Peter, Szapary, Laszlo, Tarkanyi, Gabor, Adami, Alessandro, Bandini, Fabio, Calabresi, Paolo, Frisullo, Giovanni, Renieri, Leonardo, Sangalli, Davide, Pirson, Anne V, Uyttenboogaart, Maarten, van den Wijngaard, Ido, Kristoffersen, Espen Saxhaug, Brola, Waldemar, Fudala, Małgorzata, Horoch-Lyszczarek, Ewa, Karlinski, Michal, Kazmierski, Radoslaw, Kram, Pawel, Rogoziewicz, Marcin, Kaczorowski, Rafal, Luchowski, Piotr, Sienkiewicz-Jarosz, Halina, Sobolewski, Piotr, Fryze, Waldemar, Wisniewska, Anna, Wiszniewska, Malgorzata, Ferreira, Patricia, Ferreira, Paulo, Fonseca, Luisa, Marto, João Pedro, Pinho E Melo, Teresa, Nunes, Ana Paiva, Rodrigues, Miguel, Cruz, Vítor Tedim, Falup-Pecurariu, Cristian, Krastev, Georgi, Mako, Miroslav, Alonso de Leciñana, María, Arenillas, Juan F, Ayo-Martin, Oscar, Culebras, Antonio Cruz, Tejedor, Exuperio Diez, Montaner, Joan, Pérez-Sánchez, Soledad, Tola Arribas, Miguel Angel, Vasquez, Alejandro Rodriguez, Mazya, Michael, Bernava, Gianmarco, Brehm, Alex, Machi, Paolo, Fischer, Urs, Gralla, Jan, Michel, Patrik L, Psychogios, Marios-Nikos, Strambo, Davide, Banerjee, Soma, Krishnan, Kailash, Kwan, Joseph, Butt, Asif, Catanese, Luciana, Demchuk, Andrew, Field, Thalia, Haynes, Jennifer, Hill, Michael D, Khosravani, Houman, Mackey, Ariane, Pikula, Aleksandra, Saposnik, Gustavo, Scott, Courtney Anne, Shoamanesh, Ashkan, Shuaib, Ashfaq, Yip, Samuel, Barboza, Miguel A, Barrientos, Jose Domingo, Portillo Rivera, Ligia Ibeth, Gongora-Rivera, Fernando, Novarro-Escudero, Nelson, Blanco, Anmylene, Abraham, Michael, Alsbrook, Diana, Altschul, Dorothea, Alvarado-Ortiz, Anthony J, Bach, Ivo, Badruddin, Aamir, Barazangi, Nobl, Brereton, Charmaine, Castonguay, Alicia, Chaturvedi, Seemant, Chaudhry, Saqib A, Choe, Hana, Choi, Jae H, Dharmadhikari, Sushrut, Desai, Kinjal, Devlin, Thomas G, Doss, Vinodh T, Edgell, Randall, Etherton, Mark, Farooqui, Mudassir, Frei, Don, Gandhi, Dheeraj, Grigoryan, Mikayel, Gupta, Rishi, Hassan, Ameer E, Helenius, Johanna, Kaliaev, Artem, Kaushal, Ritesh, Khandelwal, Priyank, Khawaja, Ayaz M, Khoury, Naim N, Kim, Benny S, Kleindorfer, Dawn O, Koyfman, Feliks, Lee, Vivien H, Leung, Lester Y, Linares, Guillermo, Linfante, Italo, Lutsep, Helmi L, Macdougall, Lisa, Male, Shailesh, Malik, Amer, Masoud, Hesham, McDermott, Molly, Mehta, Brijesh P, Min, Jiangyong, Mittal, Manoj, Morris, Jane G, Multani, Sumeet S, Nahab, Fadi, Nalleballe, Krishna, Nguyen, Claude B, Novakovic-White, Roberta, Ortega-Gutierrez, Santiago, Rahangdale, Rahul H, Ramakrishnan, Pankajavalli, Romero, Jose Rafael, Rost, Natalia, Rothstein, Aaron, Ruland, Sean, Shah, Ruchir, Sharma, Malveeka, Silver, Brian, Simmons, Marc, Singh, Abhishek, Starosciak, Amy K, Strasser, Sheryl L, Szeder, Viktor, Teleb, Mohamed, Tsai, Jenny P, Voetsch, Barbara, Balaguera, Oscar, Pujol Lereis, Virginia A, Luraschi, Adriana, Almeida, Marcele Schettini, Cardoso, Fabricio Buchdid, Conforto, Adriana, De Deus Silva, Leonardo, Giacomini, Luidia Varrone, Lima, Fabricio Oliveira, Longo, Alexandre L, Magalhães, Pedro Sc, Martins, Rodrigo Targa, Mont'alverne, Francisco, Mora Cuervo, Daissy Liliana, Rebello, Leticia Costa, Valler, Lenise, Zetola, Viviane Flumignan, Lavados, Pablo M, Navia, Victor, Olavarría, Verónica V, Almeida Toro, Juan Manuel, Ricardo Amaya, Pablo Felipe, Bayona, Hernan, Corredor-Quintero, Angel Basilio, Rivera Ordonez, Carlos Eduardo, Mantilla Barbosa, Diana Katherine, Lara, Osvaldo, Patiño, Mauricio R, Diaz Escobar, Luis Fernando, Dejesus Melgarejo Farina, Donoband Edson, Villamayor, Analia Cardozo, Zelaya Zarza, Adolfo Javier, Barrientos Iman, Danny Moises, Kadota, Liliana Rodriguez, Campbell, Bruce, Hankey, Graeme J, Hair, Casey, Kleinig, Timothy, Ma, Alice, Martins, Rodrigo Tomazini, Sahathevan, Ramesh, Thijs, Vincent, Salazar, Daniel, Yuan-Hao Wu, Teddy, Haussen, Diogo C, Liebeskind, David, Yavagal, Dileep, Jovin, Tudor G, Zaidat, Osama O, and Nguyen, Thanh N

Subjects
610 Medicine & health
Abstract

OBJECTIVE The objectives of this study were to measure the global impact of the pandemic on the volumes for intravenous thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with two control 4-month periods. METHODS We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified by their ICD-10 codes and/or classifications in stroke databases. RESULTS There were 91,373 stroke admissions in the 4 months immediately before compared to 80,894 admissions during the pandemic months, representing an 11.5% (95%CI, -11.7 to - 11.3, p

Published
2021
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17. Global impact of the COVID-19 pandemic on stroke care and intravenous thrombolysis (1462)

Author

Nguyen, Thanh, primary, Qureshi, Muhammad, additional, Martins, Sheila, additional, Yamagami, Hiroshi, additional, Qiu, Zhongming, additional, Mansour, Ossama, additional, Czlonkowska, Anna, additional, Abdalkader, Mohamad, additional, Sathya, Anvitha, additional, de Sousa, Diana Aguiar, additional, Demeestere, Jelle, additional, Mikulik, Robert, additional, Vanacker, Peter, additional, Siegler, James, additional, Korv, Janika, additional, Biller, Jose, additional, Liang, Conrad, additional, Sangha, Navdeep, additional, Zha, Alicia, additional, Czap, Alexandra, additional, Holmstedt, Christine, additional, Turan, Tanya, additional, Grant, Cheryl, additional, Ntaios, George, additional, Malhotra, Konard, additional, Tayal, Ashis, additional, Loochtan, Aaron, additional, Mistry, Eva, additional, Alexandrov, Anne, additional, Huang, David, additional, Yaghi, Shadi, additional, Raz, Eytan, additional, Sheth, Sunil, additional, Frankel, Michael, additional, Lamou, Eric Gueumekane Bila, additional, Aref, Hany, additional, Elbassiouny, Ahmed, additional, Hassan, Farouk, additional, Mustafa, Wessam, additional, Menecie, Tarek, additional, Shokri, Hossam, additional, Roushdy, Tamer, additional, Sarfo, Fred Stephen, additional, Alabi, Tolulope, additional, Arabambi, Babawale, additional, Nwazor, Ernest, additional, Sunmonu, Taofiki Ajao, additional, Wahab, Kolawole W., additional, Mohammed, Haythem Hussein, additional, Adebayo, Philip B., additional, Riahi, Anis, additional, Ben Sassi, Samia, additional, Gwaunza, Lenon, additional, Rahman, Aminur, additional, Ai, Zhibing, additional, Bai, Fanghui, additional, Duan, Zhenhui, additional, Hao, Yonggang, additional, Huang, Wenguo, additional, Li, Guangwen, additional, Li, Wei, additional, Liu, Ganzhe, additional, Luo, Jun, additional, Shang, Xianjin, additional, Sui, Yi, additional, Tian, Ling, additional, Wen, Hongbin, additional, Wu, Bo, additional, Yan, Yuying, additional, Yuan, Zhengzhou, additional, Zhang, Hao, additional, Zhang, Jun, additional, Zhao, Wenlong, additional, Zi, Wenjie, additional, Leung, Thomas K., additional, Sahakyan, David, additional, Chugh, Chandril, additional, Huded, Vikram, additional, Menon, Bindu, additional, Pandian, Jeyaraj, additional, Sylaja, P.N., additional, Usman, Fritz Sumantri, additional, Farhoudi, Mehdi, additional, Sadeghi-Hokmabadi, Elyar, additional, Reznik, Anna, additional, Sivan-Hoffman, Rotem, additional, Horev, Anat, additional, Ohara, Nobuyuki, additional, Sakai, Nobuyuki, additional, Watanabe, Daisuke, additional, Yamamoto, Ryoo, additional, Doijiri, Ryosuke, additional, Tokuda, Naoki, additional, Yamada, Takehiro, additional, Terasaki, Tadashi, additional, Yazawa, Yukako, additional, Uwatoko, Takeshi, additional, Dembo, Tomohisa, additional, Shimizu, Hisao, additional, Sugiura, Yuri, additional, Miyashita, Fumio, additional, Fukuda, Hiroki, additional, Miyake, Kosuke, additional, Shimbo, Junsuke, additional, Sugimura, Yusuke, additional, Yagita, Yoshika, additional, Takenobu, Yohei, additional, Matsumaru, Yuji, additional, Yamada, Satoshi, additional, Kono, Ryuhei, additional, Kanamaru, Takuya, additional, Yamazaki, Hidekazu, additional, Sakaguchi, Manabu, additional, Todo, Kenichi, additional, Yamamoto, Nobuaki, additional, Sonodda, Kazutaka, additional, Yoshida, Tomoko, additional, Hashimoto, Hiroyuki, additional, Nakahara, Ichiro, additional, Faizullina, Kamila, additional, Kamenova, Saltanat, additional, Kondybayeva, Aida, additional, Zhanuzakov, Murat, additional, Baek, Jang-Hyun, additional, Hwang, Yangha, additional, Lee, Si Baek, additional, Moon, Jusun, additional, Park, Hyungjong, additional, Seo, Jung Hwa, additional, Seo, Kwon-Duk, additional, Young, Chang Jun, additional, Ahdab, Rechdi, additional, Aziz, Zariah Abdul, additional, Zaidi, Wan Asyraf Wan, additional, Basri, Hamidon Bin, additional, Chung, Law Wan, additional, Husin, Mazlina, additional, Ibrahim, Aznita Binti, additional, Ibrahim, Khairul Azmi, additional, Looi, Irene, additional, Tan, Wee Yong, additional, Yahya, Wan Nur Nafisah Wan, additional, Groppa, Stanislav, additional, Leahu, Pavel, additional, Al Hashmi, Amal, additional, Imam, Yehai Z., additional, Akhtar, Naveed, additional, Oliver, Christian, additional, Kandyba, Dmitriy, additional, Alhazzani, Adel, additional, Al-Jehani, Hosam, additional, Tham, Carol Huilian, additional, Mamauag, Marlie Jane, additional, Narayanaswamy, Ram, additional, Chen, Chih-Hao, additional, Tang, Sung-Chun, additional, Churojana, Anchalee, additional, Aykaç, Ozlem, additional, Özdemir, Atilla Özcan, additional, Hussain, Syed Irteza, additional, John, Seby, additional, Le Vu, Huynh, additional, Tran, Anh Duc, additional, Nguyen, Huy Hoang, additional, Thong, Pham Nhu, additional, Nguyen, Thang, additional, Nguyen, Trung, additional, Gattringer, Thomas, additional, Enzinger, Christian, additional, Killer-Oberpfalzer, Monika, additional, Bellante, Flavio, additional, De Blauwe, Sofie, additional, Van Hooren, Geert, additional, De Raedt, Sylvie, additional, Dusart, Anne, additional, Ligot, Noemie, additional, Rutgers, Matthieu, additional, Yperzeele, Laetitia, additional, Alexiev, Filip, additional, Sakelarova, Teodora, additional, Bedekovic, Marina Roje, additional, Budincevic, Hrvoje, additional, Cindric, Igor, additional, Hucika, Zlatko, additional, Ozretic, David, additional, Saric, Majda Seferovic, additional, Pfeifer, František, additional, Karpowicz, Igor, additional, Cernik, David, additional, Sramek, Martin, additional, Skoda, Miroslav, additional, Hlavacova, Helena, additional, Klecka, Lukas, additional, Koutny, Martin, additional, Vaclavik, Dan, additional, Skoda, Ondrej, additional, Fiksa, Jan, additional, Hanelova, Katerina, additional, Nevsimalova, Miroslava, additional, Rezek, Robert, additional, Prochazka, Petr, additional, Krejstova, Gabriela, additional, Neumann, Jiri, additional, Vachova, Marta, additional, Brzezanski, Henry, additional, Hlinovsky, David, additional, Tenora, Dusan, additional, Jura, Rene, additional, Jurak, Lubomir, additional, Novak, Jan, additional, Novak, Ales, additional, Topinka, Zdenek, additional, Fibrich, Petr, additional, Sobolova, Helena, additional, Volny, Ondrej, additional, Christensen, Hanne Krarup, additional, Drenck, Nicolas, additional, Iversen, Helle, additional, Simonsen, Claus, additional, Truelsen, Thomas, additional, Wienecke, Troels, additional, Vibo, Riina, additional, Gross-Paju, Katrin, additional, Toomsoo, Toomas, additional, Antsov, Katrin, additional, Caparros, Francois, additional, Cordonnier, Charlotte, additional, Dan, Maria, additional, Faucheux, Jean-Marc, additional, Mechtouff, Laura, additional, Eker, Omer, additional, Lesaine, Emillie, additional, Ondze, Basile, additional, Pico, Fernando, additional, Pop, Raoul, additional, Rouanet, Francois, additional, Gubeladze, Tatuli, additional, Khinikadze, Mirza, additional, Lobjanidze, Nina, additional, Tsiskaridze, Alexander, additional, Nagel, Simon, additional, Ringleb, Peter Arthur, additional, Rosenkranz, Michael, additional, Schmidt, Holger, additional, Sedghi, Annahita, additional, Siepmann, Timo, additional, Szabo, Kristina, additional, Thomalla, Gotz, additional, Palaiodimou, Lina, additional, Sagris, Dimitrios, additional, Kargiotis, Odysseas, additional, Kaliaev, Artem, additional, Liebeskind, David, additional, Hassan, Ameer, additional, Ranta, Anna, additional, Devlin, Thomas, additional, Zaidat, Osama, additional, Castonguay, Alicia, additional, Jovin, Tudor, additional, Tsivgoulis, Georgios, additional, Malik, Amer, additional, Ma, Alice, additional, Campbell, Bruce, additional, Kleinig, Timothy, additional, Wu, Teddy, additional, Gongora, Fernando, additional, Lavados, Pablo, additional, Olavarria, Veronica, additional, Lereis, Virginia Pujol, additional, Corredor, Angel, additional, Barbosa, Diana Mantilla, additional, Bayona, Hernan, additional, Barrientos, Jose Domingo, additional, Patino, Mauricio, additional, Thijs, Vincent, additional, Pirson, Anne, additional, Kristoffersen, Espen Saxhaug, additional, Patrik, Michel, additional, Fischer, Urs, additional, Bernava, Gianmarco, additional, Renieri, Leonardo, additional, Strambo, Davide, additional, Ayo-Martin, Oscar, additional, Montaner, Joan, additional, Karlinski, Michal, additional, Cruz-Culebras, Antonio, additional, Luchowski, Piotr, additional, Krastev, Georgi, additional, Arenillas, Juan, additional, Gralla, Jan, additional, Mangiafico, Salvatore, additional, Blasco, Jordi, additional, Fonseca, Luisa, additional, Silva, M. Luis, additional, Kwan, Joseph, additional, Banerjee, Soma, additional, Sangalli, Davide, additional, Frisullo, Giovanni, additional, Yavagal, Dileep, additional, Uyttenboogaart, Maarten, additional, Bandini, Fabio, additional, Adami, Alessandro, additional, de Lecina, Maria Alonso, additional, Arribas, Miguel Angel Tola, additional, Ferreira, Paulo, additional, Cruz, Vitor Tedim, additional, Nunes, Ana Paiva, additional, Marto, Joao Pedro, additional, Rodrigues, Miguel, additional, Melo, Teresa, additional, Saposnik, Gustavo, additional, Scott, Courtney Anne, additional, Shuaib, Ashfaq, additional, Khosravani, Houman, additional, Fields, Thalia, additional, Shoamanesh, Ashkan, additional, Catanese, Luciana, additional, Mackey, Ariane, additional, Hill, Michael, additional, Etherton, Mark, additional, Rost, Natalia, additional, Lutsep, Helmi, additional, Lee, Vivien, additional, Mehta, Brijesh, additional, Pikula, Aleksandra, additional, Simmons, Marc, additional, Macdougall, Lisa, additional, Silver, Brian, additional, Khandelwal, Priyank, additional, Morris, Jane, additional, Novakovic-White, Roberta, additional, Ramakrishnan, Pankajavalli, additional, Shah, Ruchir, additional, Altschul, Dorothea, additional, Almufti, Fawaz, additional, Amaya, Pablo, additional, Ordonez, Carlos Eduardo Rivera, additional, Lara, Osvalda, additional, Kadota, Liliana Rodriguez, additional, Rivera, Ligia Ibeth Portillo, additional, Novarro, Nelson, additional, Escobar, Luis Diaz, additional, Melgarejo, Donoband, additional, Cardozo, Analia, additional, Blanco, Anmylene, additional, Zelaya, Javier Adolfo, additional, Luraschi, Adriana, additional, Gonzalez, Victor Hugo Navia, additional, Almeida, Juan, additional, Conforto, Adriana, additional, Almeida, Marcele Schettini, additional, de Deus Silva, Leonardo, additional, Cuervo, Daissy Liliana Mora, additional, Zetola, Viviane Flumignan, additional, Martins, Rodrigo Targa, additional, Valler, Lenise, additional, Giacomini, Luidia Varrone, additional, Cardoso, Fabricio Buchdid, additional, Sahathevan, Ramesh, additional, Hair, Casey, additional, Hankey, Graeme, additional, Salazar, Daniel, additional, Lima, Fabricio Oliveira, additional, Mont’Alverne, Francisco, additional, Iman, Danny Moises Barrientos, additional, Magalhaes, Pedro, additional, Longo, Alexandre, additional, Rebello, Leticia, additional, Falup-Pecurariu, Cristian, additional, Mazya, Michael, additional, Wisniewska, Anna, additional, Fryze, Waldemar, additional, Kazmierski, Radoslaw, additional, Wisniewska, Malgorzata, additional, Horoch, Ewa, additional, Sienkiewicz-Jarosz, Halina, additional, Fudala, Malgorzata, additional, Rogoziewicz, Marcin, additional, Brola, Waldemar, additional, Sobolewski, Piotr, additional, Kaczorowski, Rafal, additional, Stepien, Adam, additional, Klivenyi, Peter, additional, Szapary, Laszlo, additional, van den Wijngaard, Ido, additional, Demchuk, Andrew, additional, Abraham, Michael, additional, Alvarado-Ortiz, Tony, additional, Kaushal, Ritesh, additional, Ortega-Gutierrez, Santiago, additional, Farooqui, Mudassir, additional, Bach, Ivo, additional, Badruddin, Aamir, additional, Barazangi, Nobl, additional, Nguyen, Claude, additional, Brereton, Charmaine, additional, Choi, Jae H., additional, Dharmadhikari, Sushrut, additional, Desai, Kinjal, additional, Doss, Vinodh, additional, Edgell, Randall, additional, Linares, Guillermo, additional, Frei, Donald, additional, Chaturvedi, Seemant, additional, Gandhi, Dheeraj, additional, Chaudhry, Saqib, additional, Choe, Hana, additional, Grigoryan, Mikayel, additional, Gupta, Rishi, additional, Helenius, Johanna, additional, Voetsch, Barbara, additional, Khwaja, Ayaz, additional, Khoury, Naim, additional, Kim, Benny S., additional, Kleindorfer, Dawn, additional, McDermott, Molly, additional, Koyfman, Feliks, additional, Leung, Lester, additional, Linfante, Italo, additional, Male, Shailesh, additional, Masoud, Hesham, additional, Min, Jiangyong, additional, Mittal, Manoj, additional, Multani, Sumeet, additional, Nahab, Fadi, additional, Nalleballe, Krishna, additional, Rahangdale, Rahul, additional, Rafael, Jose, additional, Rothstein, Aaron, additional, Ruland, Sean, additional, Sharma, Malveeka, additional, Singh, Abishek, additional, Starosciak, Amy, additional, Strasser, Sheryl, additional, Szeder, Viktor, additional, Teleb, Mohamed, additional, Tsai, Jenny, additional, Mohammaden, Mahmoud, additional, Pineda-Franks, Carissa, additional, Asyraf, Wan, additional, Nguyen, Trung QuocH, additional, Tarkanyi, Gabor, additional, Haussen, Diogo, additional, Balaguera, Oscar, additional, Vasquez, Alejandro Rodriguez, additional, and Nogueira, Raul, additional

Published
2021
Full Text
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20. Synthesis of vinca alkaloids and related compounds. 79. An intriguing retro Diels-Alder reaction

Author

Szantay, Csaba, Jr., Moldvai, Istvan, Tarkanyi, Gabor, and Szantay, Csaba

Subjects
Alkaloids -- Research, Diels-Alder reaction -- Research, Acetic acid -- Research, Biological sciences, Chemistry
Abstract

A new dimer product is synthesized from the dimerization reaction of (-)-criocerine with trifluoroacetic acid. Dimer 3 is characterized by a tetrahydropyranyl ring. This affords a highly strained structure with the C(18) in a quasi-axial orientation to ring D'. Dimer 3, however, effortlessly rearranges to 4 by an intramolecular Diels-Alder reaction. The spectra of compounds 3 and 4 show overcrowded geometries with two bonds connecting the two halves of the dimers.

Published
1996

27. Synthesis and solution- and solid-state characterization of gold(I) rings with short Au...Au interactions. Spontaneous resolution of a gold(I) complex

Author

Deak, Andrea, Megyes, Tunde, Tarkanyi, Gabor, Kiraly, Peter, Biczok, Laszlo, Palinkas, Gabor, and Stang, Peter J.

Subjects
Gold compounds -- Chemical properties, Gold compounds -- Structure, Ionization -- Observations, Chemical synthesis, Chemistry
Abstract

A study demonstrates that the micelles formed by self-assembly of poly((1,2-butadiene)-block-ethylene oxide) (PB-PEO) diblock copolymers can move back and forth between an ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM]-{P[F.sub.6]}) and water without perturbing the major micellar structure. The reversible micelle transfer between the two media is based on the relative affinity of the two solvents to the corona chains and is triggered by temperature change.

Published
2006

28. X-ray diffraction and DOSY NMR characterization of self-assembled supramolecular metallocyclic species in solution

Author

Megyes, Tunde, Jude, Hershel, Grosz, Tamas, Stang, Peter J., Bako, Imre, Palinkas, Gabor, Radnai, Tamas, and Tarkanyi, Gabor

Subjects
Nuclear magnetic resonance spectroscopy -- Usage, Coordination compounds -- Research, X-rays -- Diffraction, X-rays -- Research, Chemistry
Abstract

Wide-angle X-ray scattering and diffusion NMR techniques are used to obtain structural information on three self-assembled metallacyclic supramolecular complexes in solution such as a rectangle, a triangle and a three-diminsional cage. The low-angle region of the measured diffraction pattern and hydrodynamic radii calculations, determined from DOSY NMR experiments, suggest that the supramolecular assemblies retain their shape when dissolved in nitromethane.

Published
2005

39. Global impact of the COVID-19 pandemic on stroke care and intravenous thrombolysis

Author

Thanh Nguyen, Qureshi, Muhammad, Martins, Sheila, Yamagami, Hiroshi, Qiu, Zhongming, Mansour, Ossama, Czlonkowska, Anna, Abdalkader, Mohamad, Sathya, Anvitha, Sousa, Diana Aguiar, Demeestere, Jelle, Mikulik, Robert, Vanacker, Peter, Siegler, James, Korv, Janika, Biller, Jose, Liang, Conrad, Sangha, Navdeep, Zha, Alicia, Czap, Alexandra, Holmstedt, Christine, Turan, Tanya, Grant, Cheryl, Ntaios, George, Malhotra, Konard, Tayal, Ashis, Loochtan, Aaron, Mistry, Eva, Alexandrov, Anne, Huang, David, Yaghi, Shadi, Raz, Eytan, Sheth, Sunil, Frankel, Michael, Lamou, Eric Gueumekane Bila, Aref, Hany, Elbassiouny, Ahmed, Hassan, Farouk, Mustafa, Wessam, Menecie, Tarek, Shokri, Hossam, Roushdy, Tamer, Sarfo, Fred Stephen, Alabi, Tolulope, Arabambi, Babawale, Nwazor, Ernest, Sunmonu, Taofiki Ajao, Wahab, Kolawole W., Mohammed, Haythem Hussein, Adebayo, Philip B., Riahi, Anis, Ben Sassi, Samia, Gwaunza, Lenon, Rahman, Aminur, Ai, Zhibing, Bai, Fanghui, Duan, Zhenhui, Hao, Yonggang, Huang, Wenguo, Li, Guangwen, Li, Wei, Liu, Ganzhe, Luo, Jun, Shang, Xianjin, Sui, Yi, Tian, Ling, Wen, Hongbin, Wu, Bo, Yan, Yuying, Yuan, Zhengzhou, Zhang, Hao, Zhang, Jun, Zhao, Wenlong, Zi, Wenjie, Leung, Thomas K., Sahakyan, David, Chugh, Chandril, Huded, Vikram, Menon, Bindu, Pandian, Jeyaraj, Sylaja, P. N., Usman, Fritz Sumantri, Farhoudi, Mehdi, Elyar Sadeghi Hokmabadi, Reznik, Anna, Sivan-Hoffman, Rotem, Horev, Anat, Ohara, Nobuyuki, Sakai, Nobuyuki, Watanabe, Daisuke, Yamamoto, Ryoo, Doijiri, Ryosuke, Tokuda, Naoki, Yamada, Takehiro, Terasaki, Tadashi, Yazawa, Yukako, Uwatoko, Takeshi, Dembo, Tomohisa, Shimizu, Hisao, Sugiura, Yuri, Miyashita, Fumio, Fukuda, Hiroki, Miyake, Kosuke, Shimbo, Junsuke, Sugimura, Yusuke, Yagita, Yoshika, Takenobu, Yohei, Matsumaru, Yuji, Yamada, Satoshi, Kono, Ryuhei, Kanamaru, Takuya, Yamazaki, Hidekazu, Sakaguchi, Manabu, Todo, Kenichi, Yamamoto, Nobuaki, Sonodda, Kazutaka, Yoshida, Tomoko, Hashimoto, Hiroyuki, Nakahara, Ichiro, Faizullina, Kamila, Kamenova, Saltanat, Kondybayeva, Aida, Zhanuzakov, Murat, Baek, Jang-Hyun, Hwang, Yangha, Lee, Si Baek, Moon, Jusun, Park, Hyungjong, Seo, Jung Hwa, Seo, Kwon-Duk, Young, Chang Jun, Ahdab, Rechdi, Aziz, Zariah Abdul, Zaidi, Wan Asyraf Wan, Bin Basri, Hamidon, Chung, Law Wan, Husin, Mazlina, Ibrahim, Aznita Binti, Ibrahim, Khairul Azmi, Looi, Irene, Tan, Wee Yong, Yahya, Wan Nur Nafisah Wan, Groppa, Stanislav, Leahu, Pavel, Al Hashmi, Amal, Imam, Yehai Z., Akhtar, Naveed, Oliver, Christian, Kandyba, Dmitriy, Alhazzani, Adel, Al-Jehani, Hosam, Tham, Carol Huilian, Mamauag, Marlie Jane, Narayanaswamy, Ram, Chen, Chih-Hao, Tang, Sung-Chun, Churojana, Anchalee, Aykac, Ozlem, Ozdemir, Atilla Ozcan, Hussain, Syed Irteza, John, Seby, Huynh Le Vu, Anh Duc Tran, Huy Hoang Nguyen, Pham Nhu Thong, Nguyen, Thang, Nguyen, Trung, Gattringer, Thomas, Enzinger, Christian, Killer-Oberpfalzer, Monika, Bellante, Flavio, Blauwe, Sofie, Hooren, Geert, Raedt, Sylvie, Dusart, Anne, Ligot, Noemie, Rutgers, Matthieu, Yperzeele, Laetitia, Alexiev, Filip, Sakelarova, Teodora, Bedekovic, Marina Roje, Budincevic, Hrvoje, Cindric, Igor, Hucika, Zlatko, Ozretic, David, Saric, Majda Seferovic, Pfeifer, Frantisek, Karpowicz, Igor, Cernik, David, Sramek, Martin, Skoda, Miroslav, Hlavacova, Helena, Klecka, Lukas, Koutny, Martin, Vaclavik, Dan, Skoda, Ondrej, Fiksa, Jan, Hanelova, Katerina, Nevsimalova, Miroslava, Rezek, Robert, Prochazka, Petr, Krejstova, Gabriela, Neumann, Jiri, Vachova, Marta, Brzezanski, Henry, Hlinovsky, David, Tenora, Dusan, Jura, Rene, Jurak, Lubomir, Novak, Jan, Novak, Ales, Topinka, Zdenek, Fibrich, Petr, Sobolova, Helena, Volny, Ondrej, Christensen, Hanne Krarup, Drenck, Nicolas, Iversen, Helle, Simonsen, Claus, Truelsen, Thomas, Wienecke, Troels, Vibo, Riina, Gross-Paju, Katrin, Toomsoo, Toomas, Antsov, Katrin, Caparros, Francois, Cordonnier, Charlotte, Dan, Maria, Faucheux, Jean-Marc, Mechtouff, Laura, Eker, Omer, Lesaine, Emillie, Ondze, Basile, Pico, Fernando, Pop, Raoul, Rouanet, Francois, Gubeladze, Tatuli, Khinikadze, Mirza, Lobjanidze, Nina, Tsiskaridze, Alexander, Nagel, Simon, Ringleb, Peter Arthur, Rosenkranz, Michael, Schmidt, Holger, Sedghi, Annahita, Siepmann, Timo, Szabo, Kristina, Thomalla, Gotz, Palaiodimou, Lina, Sagris, Dimitrios, Kargiotis, Odysseas, Kaliaev, Artem, Liebeskind, David, Hassan, Ameer, Ranta, Anna, Devlin, Thomas, Zaidat, Osama, Castonguay, Alicia, Jovin, Tudor, Tsivgoulis, Georgios, Malik, Amer, Ma, Alice, Campbell, Bruce, Kleinig, Timothy, Wu, Teddy, Gongora, Fernando, Lavados, Pablo, Olavarria, Veronica, Lereis, Virginia Pujol, Corredor, Angel, Barbosa, Diana Mantilla, Bayona, Hernan, Barrientos, Jose Domingo, Patino, Mauricio, Thijs, Vincent, Pirson, Anne, Kristoffersen, Espen Saxhaug, Patrik, Michel, Fischer, Urs, Bernava, Gianmarco, Renieri, Leonardo, Strambo, Davide, Ayo-Martin, Oscar, Montaner, Joan, Karlinski, Michal, Cruz-Culebras, Antonio, Luchowski, Piotr, Krastev, Georgi, Arenillas, Juan, Gralla, Jan, Mangiafico, Salvatore, Blasco, Jordi, Fonseca, Luisa, Silva, M. Luis, Kwan, Joseph, Banerjee, Soma, Sangalli, Davide, Frisullo, Giovanni, Yavagal, Dileep, Uyttenboogaart, Maarten, Bandini, Fabio, Adami, Alessandro, Lecina, Maria Alonso, Arribas, Miguel Angel Tola, Ferreira, Paulo, Cruz, Vitor Tedim, Nunes, Ana Paiva, Marto, Joao Pedro, Rodrigues, Miguel, Melo, Teresa, Saposnik, Gustavo, Scott, Courtney Anne, Shuaib, Ashfaq, Khosravani, Houman, Fields, Thalia, Shoamanesh, Ashkan, Catanese, Luciana, Mackey, Ariane, Hill, Michael, Etherton, Mark, Rost, Natalia, Lutsep, Helmi, Lee, Vivien, Mehta, Brijesh, Pikula, Aleksandra, Simmons, Marc, Macdougall, Lisa, Silver, Brian, Khandelwal, Priyank, Morris, Jane, Novakovic-White, Roberta, Ramakrishnan, Pankajavalli, Shah, Ruchir, Altschul, Dorothea, Almufti, Fawaz, Amaya, Pablo, Ordonez, Carlos Eduardo Rivera, Lara, Osvalda, Kadota, Liliana Rodriguez, Rivera, Ligia Ibeth Portillo, Novarro, Nelson, Escobar, Luis Diaz, Melgarejo, Donoband, Cardozo, Analia, Blanco, Anmylene, Zelaya, Javier Adolfo, Luraschi, Adriana, Gonzalez, Victor Hugo Navia, Almeida, Juan, Conforto, Adriana, Almeida, Marcele Schettini, Silva, Leonardo Deus, Cuervo, Daissy Liliana Mora, Zetola, Viviane Flumignan, Martins, Rodrigo Targa, Valler, Lenise, Giacomini, Luidia Varrone, Cardoso, Fabricio Buchdid, Sahathevan, Ramesh, Hair, Casey, Hankey, Graeme, Salazar, Daniel, Lima, Fabricio Oliveira, Mont Alverne, Francisco, Moises, Danny, Iman, Barrientos, Magalhaes, Pedro, Longo, Alexandre, Rebello, Leticia, Falup-Pecurariu, Cristian, Mazya, Michael, Wisniewska, Anna, Fryze, Waldemar, Kazmierski, Radoslaw, Wisniewska, Malgorzata, Horoch, Ewa, Sienkiewicz-Jarosz, Halina, Fudala, Malgorzata, Rogoziewicz, Marcin, Brola, Waldemar, Sobolewski, Piotr, Kaczorowski, Rafal, Stepien, Adam, Klivenyi, Peter, Szapary, Laszlo, Den Wijngaard, Ido, Demchuk, Andrew, Abraham, Michael, Alvarado-Ortiz, Tony, Kaushal, Ritesh, Ortega-Gutierrez, Santiago, Farooqui, Mudassir, Bach, Ivo, Badruddin, Aamir, Barazangi, Nobl, Nguyen, Claude, Brereton, Charmaine, Choi, Jae H., Dharmadhikari, Sushrut, Desai, Kinjal, Doss, Vinodh, Edgell, Randall, Linares, Guillermo, Frei, Donald, Chaturvedi, Seemant, Gandhi, Dheeraj, Chaudhry, Saqib, Choe, Hana, Grigoryan, Mikayel, Gupta, Rishi, Helenius, Johanna, Voetsch, Barbara, Khwaja, Ayaz, Khoury, Naim, Kim, Benny S., Kleindorfer, Dawn, Mcdermott, Molly, Koyfman, Feliks, Leung, Lester, Linfante, Italo, Male, Shailesh, Masoud, Hesham, Min, Jiangyong, Mittal, Manoj, Multani, Sumeet, Nahab, Fadi, Nalleballe, Krishna, Rahangdale, Rahul, Rafael, Jose, Rothstein, Aaron, Ruland, Sean, Sharma, Malveeka, Singh, Abishek, Starosciak, Amy, Strasser, Sheryl, Szeder, Viktor, Teleb, Mohamed, Tsai, Jenny, Mohammaden, Mahmoud, Pineda-Franks, Carissa, Asyraf, Wan, Trung Quoch Nguyen, Tarkanyi, Gabor, Haussen, Diogo, Balaguera, Oscar, Vasquez, Alejandro Rodriguez, Nogueira, Raul, and ​Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE)

45. Synthesis and application of a fluorous Lawesson's reagent: convenient chromatography-free product purification.

Author

Kaleta Z, Tarkanyi G, Gömöry A, Kalman F, Nagy T, and Soós T

Abstract

[reaction: see text] A fluorous analogue of Lawesson's reagent for thionation of carbonyl compounds has been developed and its use demonstrated on a series of amides, esters, and ketones. The separation of the Lawesson's reagent-derived byproducts can be achieved by a simple fluorous solid-phase extraction.

Published
2006
Full Text
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