Back to Search
Start Over
Global Impact of COVID-19 on Stroke Care and IV Thrombolysis
- Source :
- Neurology, Neurology, 2021, 96 (23), pp.e2824-e2838. ⟨10.1212/WNL.0000000000011885⟩, Repositório Científico de Acesso Aberto de Portugal, Repositório Científico de Acesso Aberto de Portugal (RCAAP), instacron:RCAAP, Neurology, American Academy of Neurology, 2021, 96 (23), pp.e2824-e2838. ⟨10.1212/WNL.0000000000011885⟩, Neurology, 96(23), E2824-E2838. LIPPINCOTT WILLIAMS & WILKINS
- Publication Year :
- 2021
- Publisher :
- HAL CCSD, 2021.
-
Abstract
- © 2021 American Academy of Neurology<br />Objective: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods. Methods: We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases. Results: There were 91,373 stroke admissions in the 4 months immediately before compared to 80,894 admissions during the pandemic months, representing an 11.5% (95% confidence interval [CI] -11.7 to -11.3, p < 0.0001) decline. There were 13,334 IVT therapies in the 4 months preceding compared to 11,570 procedures during the pandemic, representing a 13.2% (95% CI -13.8 to -12.7, p < 0.0001) drop. Interfacility IVT transfers decreased from 1,337 to 1,178, or an 11.9% decrease (95% CI -13.7 to -10.3, p = 0.001). Recovery of stroke hospitalization volume (9.5%, 95% CI 9.2-9.8, p < 0.0001) was noted over the 2 later (May, June) vs the 2 earlier (March, April) pandemic months. There was a 1.48% stroke rate across 119,967 COVID-19 hospitalizations. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was noted in 3.3% (1,722/52,026) of all stroke admissions. Conclusions: The COVID-19 pandemic was associated with a global decline in the volume of stroke hospitalizations, IVT, and interfacility IVT transfers. Primary stroke centers and centers with higher COVID-19 inpatient volumes experienced steeper declines. Recovery of stroke hospitalization was noted in the later pandemic months.
- Subjects :
- medicine.medical_specialty
MESH: Pandemics
HSJ NEU
Cross-sectional study
medicine.medical_treatment
[SDV]Life Sciences [q-bio]
SVIN COVID-19 Global Stroke Registry
MESH: Hospitalization
030204 cardiovascular system & hematology
Article
MESH: Stroke
COVID-19
cross-sectional studies
hospitalization
humans
pandemics
retrospective studies
SARS-CoV-2
stroke
03 medical and health sciences
0302 clinical medicine
MESH: Cross-Sectional Studies
Pandemic
Medicine
Humans
MESH: COVID-19
Thrombolytic Therapy
MESH: SARS-CoV-2
Stroke
Pandemics
Retrospective Studies
MESH: Thrombolytic Therapy
Rehabilitation
MESH: Humans
business.industry
Retrospective cohort study
MESH: Retrospective Studies
medicine.disease
Thrombolysis
Confidence interval
3. Good health
Hospitalization
[SDV] Life Sciences [q-bio]
Clinical research
Cross-Sectional Studies
Emergency medicine
Observational study
Neurology (clinical)
business
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- ISSN :
- 00283878 and 1526632X
- Database :
- OpenAIRE
- Journal :
- Neurology, Neurology, 2021, 96 (23), pp.e2824-e2838. ⟨10.1212/WNL.0000000000011885⟩, Repositório Científico de Acesso Aberto de Portugal, Repositório Científico de Acesso Aberto de Portugal (RCAAP), instacron:RCAAP, Neurology, American Academy of Neurology, 2021, 96 (23), pp.e2824-e2838. ⟨10.1212/WNL.0000000000011885⟩, Neurology, 96(23), E2824-E2838. LIPPINCOTT WILLIAMS & WILKINS
- Accession number :
- edsair.doi.dedup.....971fd771e0b92658bace1a98f1c43ec4