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2 results on '"Tania Salgado de Souza Torraca"'

1. Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report

Author

Benivaldo Ramos Ferreira Terceiro, Tania Salgado de Souza Torraca, Frederico Pereira Bom Braga, Ana Cristina da Costa Martins, Lucia Regina Brahim, Mauricio Naoto Saheki, Luciana de Freitas Campos Miranda, Armando de Oliveira Schubach, and Cláudia Maria Valete-Rosalino

Subjects
Mucosal leishmaniasis, Therapy, Pentamidine isethionate, Arctic medicine. Tropical medicine, RC955-962
Abstract

Abstract In Brazil, meglumine antimoniate is the first drug of choice for mucosal leishmaniasis treatment followed by amphotericin B and pentamidine isethionate. We report the case of a patient with severe mucosal lesions caused by Leishmania (Viannia) braziliensis that were difficult to treat. Over a 14-year period, the patient showed low adherence and three treatment attempts with meglumine antimoniate failed. Additionally, there was an unsatisfactory response to liposomal amphotericin B and nephrotoxicity when using amphotericin B deoxycholate that persisted after new treatment attempt with liposomal amphotericin B. Finally, healing was achieved with pentamidine isethionate and maintained during nine months of monitoring.

Published
2019
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2. Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report

Author

Maurício Naoto Saheki, Lucia Regina Brahim, Ana Cristina da Costa Martins, Luciana de Freitas Campos Miranda, Armando de Oliveira Schubach, Cláudia Maria Valete-Rosalino, Tania Salgado de Souza Torraca, Frederico Pereira Bom Braga, and Benivaldo Ramos Ferreira Terceiro

Subjects
0301 basic medicine, Microbiology (medical), medicine.medical_specialty, lcsh:Arctic medicine. Tropical medicine, Pentamidine Isethionate, lcsh:RC955-962, Meglumine antimoniate, 030106 microbiology, 030231 tropical medicine, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Pharmacotherapy, Internal medicine, Amphotericin B deoxycholate, Amphotericin B, medicine, biology, business.industry, Leishmaniasis, Mucosal leishmaniasis, medicine.disease, Leishmania, biology.organism_classification, Infectious Diseases, Parasitology, Therapy, Pentamidine isethionate, business, Pentamidine, medicine.drug
Abstract

In Brazil, meglumine antimoniate is the first drug of choice for mucosal leishmaniasis treatment followed by amphotericin B and pentamidine isethionate. We report the case of a patient with severe mucosal lesions caused by Leishmania (Viannia) braziliensis that were difficult to treat. Over a 14-year period, the patient showed low adherence and three treatment attempts with meglumine antimoniate failed. Additionally, there was an unsatisfactory response to liposomal amphotericin B and nephrotoxicity when using amphotericin B deoxycholate that persisted after new treatment attempt with liposomal amphotericin B. Finally, healing was achieved with pentamidine isethionate and maintained during nine months of monitoring.

Published
2019

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