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1. Case report: Gastric cancer‐associated membranous nephropathy that recurred after complete remission and formation of peritoneal dissemination

Author

Nobuyuki Kajiwara, Noriko Wada, Takuya Kusumoto, Yusuke Akamaru, Hiroshi Ohashi, and Kazuyuki Hayashi

Subjects
complete remission, gastric cancer, membranous nephropathy, onco‐nephrology, paraneoplastic glomerulopathy, paraneoplastic syndrome, Medicine, Medicine (General), R5-920
Abstract

Key Clinical Message Membranous nephropathy associated with malignant neoplasm may remit completely with treatment of the underlying disease. In such cases, recurrence is very rare. However, after a recurrence, attention should be paid to the possible recurrence of the underlying disease.

Published
2019
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2. A double‐lumen catheter for hemodialysis dislocated into the mediastinum

Author

Takuya Kusumoto, Kento Mitsushio, and Nobuyuki Kajiwara

Subjects
complication, hemodialysis catheter, mediastinum, vascular access devices, Medicine, Medicine (General), R5-920
Abstract

Abstract The insertion of a catheter into the mediastinum can occur in any patient as a complication. We must check for blood regurgitation not only in the blood removal line but also in the blood return line.

Published
2019
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5. Author response for 'Clinical significance of pre‐diabetes, undiagnosed diabetes, and diagnosed diabetes on clinical outcomes in COVID‐19: Integrative analysis from the Japan COVID‐19 Task Force'

Author

null Takahiro Fukushima, null Shotaro Chubachi, null Ho Namkoong, null Takanori Asakura, null Hiromu Tanaka, null Ho Lee, null Shuhei Azekawa, null Yukinori Okada, null Ryuji Koike, null Akinori Kimura, null Seiya Imoto, null Satoru Miyano, null Seishi Ogawa, null Takanori Kanai, null Koichi Fukunaga, null Shiro Otake, null Kensuke Nakagawara, null Atsuho Morita, null Mayuko Watase, null Kaori Sakurai, null Takuya Kusumoto, null Katsunori Masaki, null Hiroki Kabata, null Hirofumi Kamata, null Makoto Ishii, null Naoki Hasegawa, null Kazuhisa Takahashi, null Norihiro Harada, null Toshio Naito, null Makoto Hiki, null Yasushi Matsushita, null Haruhi Takagi, null Ryousuke Aoki, null Ai Nakamura, null Sonoko Harada, null Hitoshi Sasano, null Shinnosuke Ikemura, null Satoshi Okamori, null Hideki Terai, null Junichi Sasaki, null Hiroshi Morisaki, null Yoshifumi Uwamino, null Kosaku Nanki, null Yohei Mikami, null Sho Uchida, null Shunsuke Uno, null Rino Ishihara, null Yuta Matsubara, null Tomoyasu Nishimura, null Takunori Ogawa, null Toshiro Sato, null Tetsuya Ueda, null Masanori Azuma, null Ryuichi Saito, null Toshikatsu Sado, null Yoshimune Miyazaki, null Ryuichi Sato, null Yuki Haruta, null Tadao Nagasaki, null Yoshinori Yasui, null Yoshinori Hasegawa, null Soichiro Ueda, null Ai Tada, null Masayoshi Miyawaki, null Masaomi Yamamoto, null Eriko Yoshida, null Reina Hayashi, null Tomoki Nagasaka, null Sawako Arai, null Yutaro Kaneko, null Kana Sasaki, null Takashi Ishiguro, null Taisuke Isono, null Shun Shibata, null Yuma Matsui, null Chiaki Hosoda, null Kenji Takano, null Takashi Nishida, null Yoichi Kobayashi, null Yotaro Takaku, null Noboru Takayanagi, null Etsuko Tagaya, null Masatoshi Kawana, null Ken Arimura, null Yasushi Nakamori, null Kazuhisa Yoshiya, null Fukuki Saito, null Tomoyuki Yoshihara, null Daiki Wada, null Hiromu Iwamura, null Syuji Kanayama, null Shuhei Maruyama, null Takanori Hasegawa, null Kunihiko Takahashi, null Tatsuhiko Anzai, null Satoshi Ito, null Akifumi Endo, null Yuji Uchimura, null Yasunari Miyazaki, null Takayuki Honda, null Tomoya Tateishi, null Shuji Tohda, null Naoya Ichimura, null Kazunari Sonobe, null Chihiro Tani Sassa, null Jun Nakajima, null Masumi Ai, null Takashi Yoshiyama, null Ken Ohta, null Hiroyuki Kokuto, null Hideo Ogata, null Yoshiaki Tanaka, null Kenichi Arakawa, null Masafumi Shimoda, null Takeshi Osawa, null Yasushi Nakano, null Yukiko Nakajima, null Ryusuke Anan, null Ryosuke Arai, null Yuko Kurihara, null Yuko Harada, null Kazumi Nishio, null Yoshikazu Mutoh, null Tomonori Sato, null Reoto Takei, null Satoshi Hagimoto, null Yoichiro Noguchi, null Yasuhiko Yamano, null Hajime Sasano, null Sho Ota, null Yusuke Suzuki, null Sohei Nakayama, null Keita Masuzawa, null Tomomi Takano, null Kazuhiko Katayama, null Koji Murakami, null Mitsuhiro Yamada, null Hisatoshi Sugiura, null Hirohito Sano, null Shuichiro Matsumoto, null Nozomu Kimura, null Yoshinao Ono, null Hiroaki Baba, null Rie Baba, null Daisuke Arai, null Takayuki Ogura, null Hidenori Takahashi, null Shigehiro Hagiwara, null Genta Nagao, null Shunichiro Konishi, null Ichiro Nakachi, null Hiroki Tateno, null Isano Hase, null Shuichi Yoshida, null Shoji Suzuki, null Miki Kawada, null Hirohisa Horinouchi, null Fumitake Saito, null Keiko Mitamura, null Masao Hagihara, null Junichi Ochi, null Tomoyuki Uchida, null Ryuya Edahiro, null Yuya Shirai, null Kyuto Sonehara, null Tatsuhiko Naito, null Kenichi Yamamoto, null Shinichi Namba, null Ken Suzuki, null Takayuki Shiroyama, null Yuichi Maeda, null Takuro Nii, null Yoshimi Noda, null Takayuki Niitsu, null Yuichi Adachi, null Takatoshi Enomoto, null Saori Amiya, null Reina Hara, null Toshihiro Kishikawa, null Shuhei Yamada, null Shuhei Kawabata, null Noriyuki Kijima, null Masatoshi Takagaki, null Noa Sasa, null Yuya Ueno, null Motoyuki Suzuki, null Norihiko Takemoto, null Hirotaka Eguchi, null Takahito Fukusumi, null Takao Imai, null Munehisa Fukushima, null Haruhiko Kishima, null Hidenori Inohara, null Kazunori Tomono, null Kazuto Kato, null Haruhiko Hirata, null Yoshito Takeda, null Atsushi Kumanogoh, null Naoki Miyazawa, null Yasuhiro Kimura, null Reiko Sado, null Hideyasu Sugimoto, null Akane Kamiya, null Naota Kuwahara, null Akiko Fujiwara, null Tomohiro Matsunaga, null Yoko Sato, null Takenori Okada, null Takashi Inoue, null Toshiyuki Hirano, null Keigo Kobayashi, null Hatsuyo Takaoka, null Koichi Nishi, null Masaru Nishitsuji, null Mayuko Tani, null Junya Suzuki, null Hiroki Nakatsumi, null Hidefumi Koh, null Tadashi Manabe, null Yohei Funatsu, null Fumimaro Ito, null Takahiro Fukui, null Keisuke Shinozuka, null Sumiko Kohashi, null Masatoshi Miyazaki, null Tomohisa Shoko, null Mitsuaki Kojima, null Tomohiro Adachi, null Motonao Ishikawa, null Kenichiro Takahashi, null Kazuyoshi Watanabe, null Yoshihiro Hirai, null Hidetoshi Kawashima, null Atsuya Narita, null Kazuki Niwa, null Yoshiyuki Sekikawa, null Hisako Sageshima, null Yoshihiko Nakamura, null Kota Hoshino, null Junichi Maruyama, null Hiroyasu Ishikura, null Tohru Takata, null Takashi Ogura, null Hideya Kitamura, null Eri Hagiwara, null Kota Murohashi, null Hiroko Okabayashi, null Takao Mochimaru, null Shigenari Nukaga, null Ryosuke Satomi Yoshitaka Oyamada, null Nobuaki Mori, null Tomoya Baba, null Yasutaka Fukui, null Mitsuru Odate, null Shuko Mashimo, null Yasushi Makino, null Kazuma Yagi, null Mizuha Hashiguchi, null Junko Kagyo, null Tetsuya Shiomi, null Kodai Kawamura, null Kazuya Ichikado, null Kenta Nishiyama, null Hiroyuki Muranaka, null Kazunori Nakamura, null Satoshi Fuke, null Hiroshi Saito, null Tomoya Tsuchida, null Shigeki Fujitani, null Mumon Takita, null Daiki Morikawa, null Toru Yoshida, null Takehiro Izumo, null Minoru Inomata, null Naoyuki Kuse, null Nobuyasu Awano, null Mari Tone, null Akihiro Ito, null Toshio Odani, null Masaru Amishima, null Takeshi Hattori, null Yasuo Shichinohe, null Takashi Kagaya, null Toshiyuki Kita, null Kazuhide Ohta, null Satoru Sakagami, null Kiyoshi Koshida, null Morio Nakamura, null Koutaro Yokote, null Taka‐Aki Nakada, null Ryuzo Abe, null Taku Oshima, null Tadanaga Shimada, null Kentaro Hayashi, null Tetsuo Shimizu, null Yutaka Kozu, null Hisato Hiranuma, null Yasuhiro Gon, null Namiki Izumi, null Kaoru Nagata, null Ken Ueda, null Reiko Taki, null Satoko Hanada, null Naozumi Hashimoto, null Keiko Wakahara, null Koji Sakamoto, null Norihito Omote, null Akira Ando, null Yu Kusaka, null Takehiko Ohba, null Susumu Isogai, null Aki Ogawa, null Takuya Inoue, null Nobuhiro Kodama, null Yasunari Kaneyama, null Shunsuke Maeda, null Takashige Kuraki, null Takemasa Matsumoto, null Masahiro Harada, null Takeshi Takahashi, null Hiroshi Ono, null Toshihiro Sakurai, null Takayuki Shibusawa, null Yusuke Kawamura, null Akiyoshi Nakayama, null Hirotaka Matsuo, null Yoshifumi Kimizuka, null Akihiko Kawana, null Tomoya Sano, null Chie Watanabe, null Ryohei Suematsu, null Makoto Masuda, null Aya Wakabayashi, null Hiroki Watanabe, null Suguru Ueda, null Masanori Nishikawa Ayumi Yoshifuji, null Kazuto Ito, null Saeko Takahashi, null Kota Ishioka, null Yusuke Chihara, null Mayumi Takeuchi, null Keisuke Onoi, null Jun Shinozuka, null Atsushi Sueyoshi, null Yoji Nagasaki, null Masaki Okamoto, null Sayoko Ishihara, null Masatoshi Shimo, null Yoshihisa Tokunaga, null Masafumi Watanabe, null Sumito Inoue, null Akira Igarashi, null Masamichi Sato, null Nobuyuki Hizawa, null Yoshiaki Inoue, null Shigeru Chiba, null Kunihiro Yamagata, null Yuji Hiramatsu, null Hirayasu Kai, null Satoru Fukuyama, null Yoshihiro Eriguchi, null Akiko Yonekawa, null Keiko Kano, null Koichiro Matsumoto, null Kensuke Kanaoka, null Shoichi Ihara, null Kiyoshi Komuta, null Koichiro Asano, null Tsuyoshi Oguma, null Yoko Ito, null Satoru Hashimoto, null Masaki Yamasaki, null Yu Kasamatsu, null Yuko Komase, null Naoya Hida, null Takahiro Tsuburai, null Baku Oyama, null Yuichiro Kitagawa, null Tetsuya Fukuta, null Takahito Miyake, null Shozo Yoshida, null Shinji Ogura, null Minoru Takada, null Hidenori Kanda, null Shinji Abe, null Yuta Kono, null Yuki Togashi, null Hiroyuki Takoi, null Ryota Kikuchi, null Shinichi Ogawa, null Tomouki Ogata, null Shoichiro Ishihara, null Arihiko Kanehiro, null Shinji Ozaki, null Yasuko Fuchimoto, null Sae Wada, null Nobukazu Fujimoto, null Kei Nishiyama, null Mariko Terashima, null Satoru Beppu, null Kosuke Yoshida, null Osamu Narumoto, null Hideaki Nagai, null Nobuharu Ooshima, null Mitsuru Motegi, null Akira Umeda, null Kazuya Miyagawa, null Hisato Shimada, null Mayu Endo, null Yoshiyuki Ohira, null Hironori Sagara, null Akihiko Tanaka, null Shin Ohta, null Tomoyuki Kimura, null Yoko Shibata, null Yoshinori Tanino, null Takefumi Nikaido, null Hiroyuki Minemura, null Yuki Sato, null Yuichiro Yamada, null Takuya Hashino, null Masato Shinoki, null Hajime Iwagoe, null Hiroshi Takahashi, null Kazuhiko Fujii, null Hiroto Kishi, null Tomoo Ishii, null Masayuki Kanai, null Tomonori Imamura, null Tatsuya Yamashita, null Masakiyo Yatomi, null Toshitaka Maeno, null Shinichi Hayashi, null Mai Takahashi, null Mizuki Kuramochi, null Isamu Kamimaki, null Yoshiteru Tominaga, null Mitsuyoshi Utsugi, null Akihiro Ono, null Toru Tanaka, null Takeru Kashiwada, null Kazue Fujita, null Yoshinobu Saito, null Masahiro Seike, null Masahiro Kanai, null Ryunosuke Saiki, null Takayoshi Hyugaji, null Eigo Shimizu, null Kotoe Katayama, null Satoru Miyawaki, null Meiko Takahashi, null Fumihiko Matsuda, null Yosuke Omae, null Yasuhito Nannya, null Takafumi Ueno, null Yuko Kitagawa, null Katsushi Tokunaga, and null The Japan COVID‐19 Task Force

Published
2022
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6. Case report: Gastric cancer‐associated membranous nephropathy that recurred after complete remission and formation of peritoneal dissemination

Author

Noriko Wada, Nobuyuki Kajiwara, Takuya Kusumoto, Hiroshi Ohashi, Yusuke Akamaru, and Kazuyuki Hayashi

Subjects
medicine.medical_specialty, recurrence, complete remission, lcsh:Medicine, Case Report, Case Reports, 030204 cardiovascular system & hematology, paraneoplastic syndrome, Gastroenterology, Onco nephrology, 03 medical and health sciences, 0302 clinical medicine, Membranous nephropathy, Internal medicine, medicine, lcsh:R5-920, business.industry, gastric cancer, lcsh:R, Complete remission, Cancer, membranous nephropathy, peritoneal dissemination, General Medicine, medicine.disease, paraneoplastic glomerulopathy, Underlying disease, 030220 oncology & carcinogenesis, onco‐nephrology, business, lcsh:Medicine (General)
Abstract

Key Clinical Message Membranous nephropathy associated with malignant neoplasm may remit completely with treatment of the underlying disease. In such cases, recurrence is very rare. However, after a recurrence, attention should be paid to the possible recurrence of the underlying disease.

Published
2019

7. Rupture-Like Shrinkage and Regrowth of Endolymphatic Hydrops in Ménière's Disease During Remission

Author

Takuya Kusumoto, Shiro Akahani, Hidehiko Okamoto, Munehisa Fukushima, Noriaki Takeda, Hidenori Inohara, and Yu Suekata

Subjects
medicine.medical_specialty, Disease, Hearing, Vertigo, Remission phase, medicine, Hearing improvement, Humans, Endolymphatic Hydrops, Endolymphatic hydrops, Meniere Disease, medicine.diagnostic_test, biology, business.industry, Magnetic resonance imaging, biology.organism_classification, medicine.disease, Magnetic Resonance Imaging, Sensory Systems, Pathophysiology, Otorhinolaryngology, Neurology (clinical), Radiology, business, Meniere's disease
Abstract

Objective To clarify pathophysiological characteristics of Meniere's disease during the remission phase. Patients Two Meniere's disease patients with different disease durations, whose endolymphatic hydrops was longitudinally observed using 3-T magnetic resonance imaging. Interventions Diagnostic. Main outcomes and measures Morphological changes of endolymphatic hydrops visualized using 3-T magnetic resonance imaging. Results Rupture-like shrinkage and regrowth of endolymphatic hydrops during the remission phase was observed in both patients. Conclusion The remission phase with hearing improvement could be as important as vertigo attacks in Meniere's disease.

Published
2021

9. A double‐lumen catheter for hemodialysis dislocated into the mediastinum

Author

Nobuyuki Kajiwara, Kento Mitsushio, and Takuya Kusumoto

Subjects
medicine.medical_specialty, medicine.medical_treatment, Hemodialysis Catheter, lcsh:Medicine, complication, Regurgitation (circulation), 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Double lumen catheter, medicine, lcsh:R5-920, hemodialysis catheter, business.industry, lcsh:R, fungi, Mediastinum, food and beverages, General Medicine, vascular access devices, mediastinum, Surgery, Catheter, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Clinical Image, Hemodialysis, business, Complication, lcsh:Medicine (General), Vascular Access Devices
Abstract

The insertion of a catheter into the mediastinum can occur in any patient as a complication. We must check for blood regurgitation not only in the blood removal line but also in the blood return line.

Published
2019

10. Effects of dark pools on financial markets’ efficiency and price discovery function: an investigation by multi-agent simulations

Author

Shintaro Kosugi, Kiyoshi Izumi, Takanobu Mizuta, Takuya Kusumoto, and Wataru Matsumoto

Subjects
Microeconomics, Market rate, Price mechanism, Financial market, Systemic risk, Economics, Market price, Dark liquidity, Price discovery, Market liquidity
Abstract

In financial stock markets, dark pools, in which order books or quotes are not provided, are becoming widely used. However, increasing the use of dark pools would raise regulatory concerns as it may ultimately affect the quality of the price discovery function in the lit markets, which are normal markets in which all order books are provided to investors. This may destabilize a market and heighten financial systemic risk. In this study, we investigated effects of a dark pool on financial markets’ efficiency and the price discovery function by using an artificial market model. We found that the markets are made more efficient by raising the share of the trading value amount of the dark pool by a certain level. However, raising the share above the level makes the market significantly inefficient. This indicates that the dark pool has an optimal usage rate for market efficiency . The smart order routing (SOR) is transmitting market orders to the dark pool, and this leads the depth of limit orders to become thicker. The thicker limit orders absorb market orders, and thus a market price is still stable near a fundamental price. On the other hand, when too many waiting orders are stored in the dark pool, the orders absorb market orders in the lit market by SOR and prevent the market price converging to the fundamental price. This causes the market price to stay very different from the fundamental price and makes the lit market inefficient. We also discuss mechanisms by which a dark pool makes a market efficient or inefficient by using a simple equation model. The equations suggest that if the trading value amount is higher in dark pools than in lit markets, markets become inefficient. This suggests that when the usage rate of dark pools is low, dark pools rarely destroy the price discovery function even though a large buy–sell imbalance occurs. On the other hand, when the usage rate of dark pools is very high, dark pools very easily destroy the price discovery function by a very slight buy–sell imbalance. We also compared results of the equations with those of simulations and found similar tendencies .

Published
2015
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11. Effects of Price Regulations and Dark Pools on Financial Market Stability: An Investigation by Multiagent Simulations

Author

Isao Yagi, Shinobu Yoshimura, Wataru Matsumoto, Takanobu Mizuta, Takuya Kusumoto, Shintaro Kosugi, and Kiyoshi Izumi

Subjects
Actuarial science, business.industry, 05 social sciences, Financial market, 02 engineering and technology, Price variation, General Business, Management and Accounting, Artificial market, Stability (probability), Term (time), 0502 economics and business, 0202 electrical engineering, electronic engineering, information engineering, Econometrics, Economics, Range (statistics), Dark liquidity, 020201 artificial intelligence & image processing, 050207 economics, business, Finance, Financial services
Abstract

We built an artificial market model and investigated the impact of large erroneous orders on financial market price formations. Comparing the case of consented large erroneous orders in the short term with that of continuous small erroneous orders in the long term, if amounts of orders are the same, we found that the orders induced almost the same price fall range. We also analysed effects of price variation limits for erroneous orders and found that price variation limits that employ a limitation term shorter than the time erroneous orders exist effectively prevent large price fluctuations. We also investigated effects of up-tick rules, adopting the trigger method that the Japan Financial Services Agency adopted in November 2013.

Published
2015
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12. Cover Image

Author

Nobuyuki Kajiwara, Noriko Wada, Takuya Kusumoto, Yusuke Akamaru, Hiroshi Ohashi, and Kazuyuki Hayashi

Subjects
General Medicine, Cover Image
Abstract

The cover image is based on the Case Report Case report: Gastric cancer‐associated membranous nephropathy that recurred after complete remission and formation of peritoneal dissemination by Nobuyuki Kajiwara et al., DOI: 10.1002/ccr3.2002.

Published
2019

13. Impact of Market Maker to Efficiency of Stock Market with Dark Pool - Artificial Market Approach

Author

Kiyoshi Izumi, Takuma Torii, Shin Nishioka, Takuya Kusumoto, and Wataru Matsumoto

Subjects
Computer science, 0206 medical engineering, 02 engineering and technology, 020601 biomedical engineering, Artificial market, Market maker, Microeconomics, 03 medical and health sciences, 0302 clinical medicine, Artificial Intelligence, Dark liquidity, Stock market, 030217 neurology & neurosurgery, Software
Published
2017
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15. Impact of Market Maker to Efficiency of Stock Market with Dark Pool - Artificial Market Approach.

Author

Shin Nishioka, Takuma Torii, Takuya Kusumoto, Wataru Matsumoto, and Kiyoshi Izumi

Abstract

In recent financial market, high frequency traders (HFTs) and dark pools have been increasing their share. Financial analysts have speculated that they might decrease market transparency and malfunction price discovery, and their interaction would make the situation worse. To validate speculations, artificial market simulation is a tool of study by constructing virtual markets on computers. In this research, by constructing an artificial market simulation, we analyzed how the interaction between HFTs and a dark pool impacts on the market efficiency (in the sense of price discovery) of a (lit) stock market. In simulations, two types of trader agents enter the market. A market maker agent, a representative strategy of HFTs, submit orders to the lit market. We analyzed the market maker's interest rate spread, or simply the spread, as a key parameter for their strategy. Stylized trader agents submit orders to either the lit market or the dark pool with some probability given as a parameter. The simulation results suggest that on the condition that market makers have little impact to market pricing (having a large spread), moderate use of dark pools can promote market pricing. On the other hand, on the condition that market makers have big impact to market pricing, excessive use of dark pools can inhibit market pricing, while using dark pools do not have bad influence when the rate of use is not high. On the influence of market makers, our results suggest that the bigger the impact to market pricing (a small spread), the more it can promote market pricing. [ABSTRACT FROM AUTHOR]

Published
2017

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