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1. A model order reduction of hysteretic eddy-current fields in electric machines using Cauer ladder network method

Author

M. Tobita and T. Matsuo

Subjects
Physics, QC1-999
Abstract

This study aims to establish a hysteretic model order reduction method for electric machines using the Cauer ladder network (CLN) method. The first inductor of the CLN represents the hysteresis effect, which is computed using the scalar play model identified from the static I–ϕ (current–magnetic flux) loops. An iron-core inductor was analyzed, and pulse-width modulation (PWM) voltage input was applied to the coil. The proposed method yielded results that agreed with the transient finite element (FE) analysis and effectively reduced the computation time.

Published
2023
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2. Decomposition of mechanical stress effect on the magnetic property of silicon steel sheet

Author

H. Shimizu, Y. Marumo, Y. Mishima, and T. Matsuo

Subjects
Physics, QC1-999
Abstract

A principal stress decomposition method was examined and compared with the equivalent stress theory to evaluate the stress-dependent magnetic properties of nonoriented silicon steel. A physical magnetization model, the multidomain particle model, was used to simulate the stress dependence of the magnetic properties by applying mechanical stress in different directions relative to the magnetic field direction. Experimental and computational tests show that even though the principal stress decomposition method provides a reasonable evaluation of the stress-dependent properties in the stress direction, it fails to accurately predict the properties in the perpendicular direction. To improve the prediction accuracy, a modified decomposition method is proposed, which gives a reasonable evaluation of the stress dependence of BH loops, permeability and hysteresis loss even when the magnetization direction is different from the stress direction.

Published
2023
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3. Deriving column-integrated thermospheric temperature with the N2 Lyman–Birge–Hopfield (2,0) band

Author

C. Cantrall and T. Matsuo

Subjects
Environmental engineering, TA170-171, Earthwork. Foundations, TA715-787
Abstract

This paper presents a new technique to derive thermospheric temperature from space-based disk observations of far ultraviolet airglow. The technique, guided by findings from principal component analysis of synthetic daytime Lyman–Birge–Hopfield (LBH) disk emissions, uses a ratio of the emissions in two spectral channels that together span the LBH (2,0) band to determine the change in band shape with respect to a change in the rotational temperature of N2. The two-channel-ratio approach limits representativeness and measurement error by only requiring measurement of the relative magnitudes between two spectral channels and not radiometrically calibrated intensities, simplifying the forward model from a full radiative transfer model to a vibrational–rotational band model. It is shown that the derived temperature should be interpreted as a column-integrated property as opposed to a temperature at a specified altitude without utilization of a priori information of the thermospheric temperature profile. The two-channel-ratio approach is demonstrated using NASA GOLD Level 1C disk emission data for the period of 2–8 November 2018 during which a moderate geomagnetic storm has occurred. Due to the lack of independent thermospheric temperature observations, the efficacy of the approach is validated through comparisons of the column-integrated temperature derived from GOLD Level 1C data with the GOLD Level 2 temperature product as well as temperatures from first principle and empirical models. The storm-time thermospheric response manifested in the column-integrated temperature is also shown to corroborate well with hemispherically integrated Joule heating rates, ESA SWARM mass density at 460 km, and GOLD Level 2 column O/N2 ratio.

Published
2021
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4. OPERA tau neutrino charged current interactions

Author

N. Agafonova, A. Alexandrov, A. Anokhina, S. Aoki, A. Ariga, T. Ariga, A. Bertolin, C. Bozza, R. Brugnera, A. Buonaura, S. Buontempo, M. Chernyavskiy, A. Chukanov, L. Consiglio, N. D’Ambrosio, G. De Lellis, M. De Serio, P. del Amo Sanchez, A. Di Crescenzo, D. Di Ferdinando, N. Di Marco, S. Dmitrievsky, M. Dracos, D. Duchesneau, S. Dusini, T. Dzhatdoev, J. Ebert, A. Ereditato, R. A. Fini, F. Fornari, T. Fukuda, G. Galati, A. Garfagnini, V. Gentile, J. Goldberg, S. Gorbunov, Y. Gornushkin, G. Grella, A. M. Guler, C. Gustavino, C. Hagner, T. Hara, T. Hayakawa, A. Hollnagel, K. Ishiguro, A. Iuliano, K. Jakovčić, C. Jollet, C. Kamiscioglu, M. Kamiscioglu, S. H. Kim, N. Kitagawa, B. Kliček, K. Kodama, M. Komatsu, U. Kose, I. Kreslo, F. Laudisio, A. Lauria, A. Lavasa, A. Longhin, P. Loverre, A. Malgin, G. Mandrioli, T. Matsuo, V. Matveev, N. Mauri, E. Medinaceli, A. Meregaglia, S. Mikado, M. Miyanishi, F. Mizutani, P. Monacelli, M. C. Montesi, K. Morishima, M. T. Muciaccia, N. Naganawa, T. Naka, M. Nakamura, T. Nakano, K. Niwa, S. Ogawa, N. Okateva, K. Ozaki, A. Paoloni, B. D. Park, L. Pasqualini, A. Pastore, L. Patrizii, H. Pessard, D. Podgrudkov, N. Polukhina, M. Pozzato, F. Pupilli, M. Roda, T. Roganova, H. Rokujo, G. Rosa, O. Ryazhskaya, O. Sato, I. Shakirianova, A. Schembri, T. Shchedrina, E. Shibayama, H. Shibuya, T. Shiraishi, T. Šimko, S. Simone, C. Sirignano, G. Sirri, A. Sotnikov, M. Spinetti, L. Stanco, N. Starkov, S. M. Stellacci, M. Stipčević, P. Strolin, S. Takahashi, M. Tenti, F. Terranova, V. Tioukov, I. Tsanaktsidis, S. Tufanli, A. Ustyuzhanin, S. Vasina, M. Vidal García, P. Vilain, E. Voevodina, L. Votano, J. L. Vuilleumier, G. Wilquet, and C. S. Yoon

Subjects
Science
Abstract

Measurement(s) tau neutrino Technology Type(s) detector Sample Characteristic - Environment neutrino beam Sample Characteristic - Location Laboratori Nazionali del Gran Sasso Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9.figshare.14979858

Published
2021
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5. Lower-thermosphere–ionosphere (LTI) quantities: current status of measuring techniques and models

Author

M. Palmroth, M. Grandin, T. Sarris, E. Doornbos, S. Tourgaidis, A. Aikio, S. Buchert, M. A. Clilverd, I. Dandouras, R. Heelis, A. Hoffmann, N. Ivchenko, G. Kervalishvili, D. J. Knudsen, A. Kotova, H.-L. Liu, D. M. Malaspina, G. March, A. Marchaudon, O. Marghitu, T. Matsuo, W. J. Miloch, T. Moretto-Jørgensen, D. Mpaloukidis, N. Olsen, K. Papadakis, R. Pfaff, P. Pirnaris, C. Siemes, C. Stolle, J. Suni, J. van den IJssel, P. T. Verronen, P. Visser, and M. Yamauchi

Subjects
Science, Physics, QC1-999, Geophysics. Cosmic physics, QC801-809
Abstract

The lower-thermosphere–ionosphere (LTI) system consists of the upper atmosphere and the lower part of the ionosphere and as such comprises a complex system coupled to both the atmosphere below and space above. The atmospheric part of the LTI is dominated by laws of continuum fluid dynamics and chemistry, while the ionosphere is a plasma system controlled by electromagnetic forces driven by the magnetosphere, the solar wind, as well as the wind dynamo. The LTI is hence a domain controlled by many different physical processes. However, systematic in situ measurements within this region are severely lacking, although the LTI is located only 80 to 200 km above the surface of our planet. This paper reviews the current state of the art in measuring the LTI, either in situ or by several different remote-sensing methods. We begin by outlining the open questions within the LTI requiring high-quality in situ measurements, before reviewing directly observable parameters and their most important derivatives. The motivation for this review has arisen from the recent retention of the Daedalus mission as one among three competing mission candidates within the European Space Agency (ESA) Earth Explorer 10 Programme. However, this paper intends to cover the LTI parameters such that it can be used as a background scientific reference for any mission targeting in situ observations of the LTI.

Published
2021
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6. First observation of a tau neutrino charged current interaction with charm production in the OPERA experiment

Author

N. Agafonova, A. Aleksandrov, A. Anokhina, S. Aoki, A. Ariga, T. Ariga, A. Bertolin, C. Bozza, R. Brugnera, A. Buonaura, S. Buontempo, M. Chernyavskiy, A. Chukanov, L. Consiglio, N. D’Ambrosio, G. De Lellis, M. De Serio, P. del Amo Sanchez, A. Di Crescenzo, D. Di Ferdinando, N. Di Marco, S. Dmitrievski, M. Dracos, D. Duchesneau, S. Dusini, T. Dzhatdoev, J. Ebert, A. Ereditato, R. A. Fini, F. Fornari, T. Fukuda, G. Galati, A. Garfagnini, V. Gentile, J. Goldberg, S. Gorbunov, Y. Gornushkin, G. Grella, A. M. Guler, C. Gustavino, C. Hagner, T. Hara, T. Hayakawa, A. Hollnagel, K. Ishiguro, A. Iuliano, K. Jakovcic, C. Jollet, C. Kamiscioglu, M. Kamiscioglu, S. H. Kim, N. Kitagawa, B. Klicek, K. Kodama, M. Komatsu, U. Kose, I. Kreslo, F. Laudisio, A. Lauria, A. Longhin, P. Loverre, A. Malgin, M. Malenica, G. Mandrioli, T. Matsuo, V. Matveev, N. Mauri, E. Medinaceli, A. Meregaglia, S. Mikado, M. Miyanishi, F. Mizutani, P. Monacelli, M. C. Montesi, K. Morishima, M. T. Muciaccia, N. Naganawa, T. Naka, M. Nakamura, T. Nakano, K. Niwa, N. Okateva, S. Ogawa, K. Ozaki, A. Paoloni, L. Paparella, B. D. Park, L. Pasqualini, A. Pastore, L. Patrizii, H. Pessard, D. Podgrudkov, N. Polukhina, M. Pozzato, F. Pupilli, M. Roda, T. Roganova, H. Rokujo, G. Rosa, O. Ryazhskaya, O. Sato, A. Schembri, I. Shakirianova, T. Shchedrina, H. Shibuya, E. Shibayama, T. Shiraishi, S. Simone, C. Sirignano, G. Sirri, A. Sotnikov, M. Spinetti, L. Stanco, N. Starkov, S. M. Stellacci, M. Stipcevic, P. Strolin, S. Takahashi, M. Tenti, F. Terranova, V. Tioukov, S. Vasina, P. Vilain, E. Voevodina, L. Votano, J. L. Vuilleumier, G. Wilquet, and C. S. Yoon

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract An event topology with two secondary vertices compatible with the decay of short-lived particles was found in the analysis of neutrino interactions in the OPERA target. The observed topology is compatible with tau neutrino charged current (CC) interactions with charm production and neutrino neutral current (NC) interactions with $$c\overline{c}$$ cc¯ pair production. However, other processes can mimic this topology. A dedicated analysis was implemented to identify the underlying process. A Monte Carlo simulation was developed and complementary procedures were introduced in the kinematic reconstruction. A multivariate analysis technique was used to achieve an optimal separation of signal from background. Most likely, this event is a $$\nu _{\tau }$$ ντ CC interaction with charm production, the tau and charm particle decaying into 1 prong and 2 prongs, respectively. The significance of this observation is evaluated.

Published
2020
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9. Final results of the search for ν μ → ν e oscillations with the OPERA detector in the CNGS beam

Author

The OPERA collaboration, N. Agafonova, A. Aleksandrov, A. Anokhina, S. Aoki, A. Ariga, T. Ariga, A. Bertolin, C. Bozza, R. Brugnera, A. Buonaura, S. Buontempo, M. Chernyavskiy, A. Chukanov, L. Consiglio, N. D’Ambrosio, G. De Lellis, M. De Serio, P. del Amo Sanchez, A. Di Crescenzo, D. Di Ferdinando, N. Di Marco, S. Dmitrievsky, M. Dracos, D. Duchesneau, S. Dusini, T. Dzhatdoev, J. Ebert, A. Ereditato, J. Favier, R. A. Fini, F. Fornari, T. Fukuda, G. Galati, A. Garfagnini, V. Gentile, J. Goldberg, Y. Gornushkin, S. Gorbunov, G. Grella, A. M. Guler, C. Gustavino, C. Hagner, T. Hara, T. Hayakawa, A. Hollnagel, B. Hosseini, K. Ishiguro, A. Iuliano, K. Jakovcic, C. Jollet, C. Kamiscioglu, M. Kamiscioglu, S. H. Kim, N. Kitagawa, B. Klicek, K. Kodama, M. Komatsu, U. Kose, I. Kreslo, F. Laudisio, A. Lauria, A. Ljubicic, A. Longhin, P. Loverre, A. Malgin, M. Malenica, G. Mandrioli, T. Matsuo, V. Matveev, N. Mauri, E. Medinaceli, F. Meisel, A. Meregaglia, S. Mikado, M. Miyanishi, F. Mizutani, P. Monacelli, M. C. Montesi, K. Morishima, M. T. Muciaccia, N. Naganawa, T. Naka, M. Nakamura, T. Nakano, K. Niwa, N. Okateva, S. Ogawa, K. Ozaki, A. Paoloni, L. Paparella, B. D. Park, L. Pasqualini, A. Pastore, L. Patrizii, H. Pessard, D. Podgrudkov, N. Polukhina, M. Pozzato, F. Pupilli, M. Roda, T. Roganova, H. Rokujo, G. Rosa, O. Ryazhskaya, O. Sato, A. Schembri, I. Shakiryanova, T. Shchedrina, H. Shibuya, E. Shibayama, T. Shiraishi, S. Simone, C. Sirignano, G. Sirri, A. Sotnikov, M. Spinetti, L. Stanco, N. Starkov, S. M. Stellacci, M. Stipcevic, P. Strolin, S. Takahashi, M. Tenti, F. Terranova, V. Tioukov, S. Vasina, P. Vilain, E. Voevodina, L. Votano, J. L. Vuilleumier, G. Wilquet, and C. S. Yoon

Subjects
Neutrino Detectors and Telescopes (experiments), Oscillation, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The OPERA experiment has discovered the tau neutrino appearance in the CNGS muon neutrino beam, in agreement with the 3 neutrino flavour oscillation hypothesis. The OPERA neutrino interaction target, made of Emulsion Cloud Chambers, was particularly efficient in the reconstruction of electromagnetic showers. Moreover, thanks to the very high granularity of the emulsion films, showers induced by electrons can be distinguished from those induced by π 0s, thus allowing the detection of charged current interactions of electron neutrinos. In this paper the results of the search for electron neutrino events using the full dataset are reported. An improved method for the electron neutrino energy estimation is exploited. Data are compatible with the 3 neutrino flavour mixing model expectations and are used to set limits on the oscillation parameters of the 3+1 neutrino mixing model, in which an additional mass eigenstate m 4 is introduced. At high Δm 412 (≳0.1 eV2), an upper limit on sin2 2θ μe is set to 0.021 at 90% C.L. and Δm 412 ≳ 4 × 10− 3 eV2 is excluded for maximal mixing in appearance mode.

Published
2018
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10. Study of charged hadron multiplicities in charged-current neutrino–lead interactions in the OPERA detector

Author

N. Agafonova, A. Aleksandrov, A. Anokhina, S. Aoki, A. Ariga, T. Ariga, A. Bertolin, I. Bodnarchuk, C. Bozza, R. Brugnera, A. Buonaura, S. Buontempo, M. Chernyavskiy, A. Chukanov, L. Consiglio, N. D’Ambrosio, G. De Lellis, M. De Serio, P. del Amo Sanchez, A. Di Crescenzo, D. Di Ferdinando, N. Di Marco, S. Dmitrievski, M. Dracos, D. Duchesneau, S. Dusini, T. Dzhatdoev, J. Ebert, A. Ereditato, R. A. Fini, F. Fornari, T. Fukuda, G. Galati, A. Garfagnini, V. Gentile, J. Goldberg, Y. Gornushkin, S. Gorbunov, G. Grella, A. M. Guler, C. Gustavino, C. Hagner, T. Hara, T. Hayakawa, A. Hollnagel, B. Hosseini, K. Ishiguro, K. Jakovcic, C. Jollet, C. Kamiscioglu, M. Kamiscioglu, S. H. Kim, N. Kitagawa, B. Klicek, K. Kodama, M. Komatsu, U. Kose, I. Kreslo, F. Laudisio, A. Lauria, A. Ljubicic, A. Longhin, P. Loverre, A. Malgin, M. Malenica, G. Mandrioli, T. Matsuo, V. Matveev, N. Mauri, E. Medinaceli, A. Meregaglia, S. Mikado, M. Miyanishi, F. Mizutani, P. Monacelli, M. C. Montesi, K. Morishima, M. T. Muciaccia, N. Naganawa, T. Naka, M. Nakamura, T. Nakano, K. Niwa, N. Okateva, S. Ogawa, K. Ozaki, A. Paoloni, L. Paparella, B. D. Park, L. Pasqualini, A. Pastore, L. Patrizii, H. Pessard, D. Podgrudkov, N. Polukhina, M. Pozzato, F. Pupilli, M. Roda, T. Roganova, H. Rokujo, G. Rosa, O. Ryazhskaya, O. Sato, A. Schembri, I. Shakirianova, T. Shchedrina, H. Shibuya, E. Shibayama, T. Shiraishi, S. Simone, C. Sirignano, G. Sirri, A. Sotnikov, M. Spinetti, L. Stanco, N. Starkov, S. M. Stellacci, M. Stipcevic, P. Strolin, S. Takahashi, M. Tenti, F. Terranova, V. Tioukov, S. Vasina, P. Vilain, E. Voevodina, L. Votano, J. L. Vuilleumier, G. Wilquet, B. Wonsak, and C. S. Yoon

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The OPERA experiment was designed to search for $$\nu _{\mu } \rightarrow \nu _{\tau }$$ νμ→ντ oscillations in appearance mode through the direct observation of tau neutrinos in the CNGS neutrino beam. In this paper, we report a study of the multiplicity of charged particles produced in charged-current neutrino interactions in lead. We present charged hadron average multiplicities, their dispersion and investigate the KNO scaling in different kinematical regions. The results are presented in detail in the form of tables that can be used in the validation of Monte Carlo generators of neutrino–lead interactions.

Published
2018
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11. Ionospheric assimilation of radio occultation and ground-based GPS data using non-stationary background model error covariance

Author

C. Y. Lin, T. Matsuo, J. Y. Liu, C. H. Lin, H. F. Tsai, and E. A. Araujo-Pradere

Subjects
Environmental engineering, TA170-171, Earthwork. Foundations, TA715-787
Abstract

Ionospheric data assimilation is a powerful approach to reconstruct the 3-D distribution of the ionospheric electron density from various types of observations. We present a data assimilation model for the ionosphere, based on the Gauss–Markov Kalman filter with the International Reference Ionosphere (IRI) as the background model, to assimilate two different types of slant total electron content (TEC) observations from ground-based GPS and space-based FORMOSAT-3/COSMIC (F3/C) radio occultation. Covariance models for the background model error and observational error play important roles in data assimilation. The objective of this study is to investigate impacts of stationary (location-independent) and non-stationary (location-dependent) classes of the background model error covariance on the quality of assimilation analyses. Location-dependent correlations are modeled using empirical orthogonal functions computed from an ensemble of the IRI outputs, while location-independent correlations are modeled using a Gaussian function. Observing system simulation experiments suggest that assimilation of slant TEC data facilitated by the location-dependent background model error covariance yields considerably higher quality assimilation analyses. Results from assimilation of real ground-based GPS and F3/C radio occultation observations over the continental United States are presented as TEC and electron density profiles. Validation with the Millstone Hill incoherent scatter radar data and comparison with the Abel inversion results are also presented. Our new ionospheric data assimilation model that employs the location-dependent background model error covariance outperforms the earlier assimilation model with the location-independent background model error covariance, and can reconstruct the 3-D ionospheric electron density distribution satisfactorily from both ground- and space-based GPS observations.

Published
2015
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12. Erratum to: Study of charged hadron multiplicities in charged-current neutrino–lead interactions in the OPERA detector

Author

N. Agafonova, A. Aleksandrov, A. Anokhina, S. Aoki, A. Ariga, T. Ariga, A. Bertolin, I. Bodnarchuk, C. Bozza, R. Brugnera, A. Buonaura, S. Buontempo, M. Chernyavskiy, A. Chukanov, L. Consiglio, N. D’Ambrosio, G. De Lellis, M. De Serio, P. del Amo Sanchez, A. Di Crescenzo, D. Di Ferdinando, N. Di Marco, S. Dmitrievski, M. Dracos, D. Duchesneau, S. Dusini, T. Dzhatdoev, J. Ebert, A. Ereditato, R. A. Fini, F. Fornari, T. Fukuda, G. Galati, A. Garfagnini, V. Gentile, J. Goldberg, Y. Gornushkin, S. Gorbunov, G. Grella, A. M. Guler, C. Gustavino, C. Hagner, T. Hara, T. Hayakawa, A. Hollnagel, B. Hosseini, K. Ishiguro, K. Jakovcic, C. Jollet, C. Kamiscioglu, M. Kamiscioglu, S. H. Kim, N. Kitagawa, B. Klicek, K. Kodama, M. Komatsu, U. Kose, I. Kreslo, F. Laudisio, A. Lauria, A. Ljubicic, A. Longhin, P. Loverre, A. Malgin, M. Malenica, G. Mandrioli, T. Matsuo, V. Matveev, N. Mauri, E. Medinaceli, A. Meregaglia, S. Mikado, M. Miyanishi, F. Mizutani, P. Monacelli, M. C. Montesi, K. Morishima, M. T. Muciaccia, N. Naganawa, T. Naka, M. Nakamura, T. Nakano, K. Niwa, N. Okateva, S. Ogawa, K. Ozaki, A. Paoloni, L. Paparella, B. D. Park, L. Pasqualini, A. Pastore, L. Patrizii, H. Pessard, D. Podgrudkov, N. Polukhina, M. Pozzato, F. Pupilli, M. Roda, T. Roganova, H. Rokujo, G. Rosa, O. Ryazhskaya, O. Sato, A. Schembri, I. Shakirianova, T. Shchedrina, H. Shibuya, E. Shibayama, T. Shiraishi, S. Simone, C. Sirignano, G. Sirri, A. Sotnikov, M. Spinetti, L. Stanco, N. Starkov, S. M. Stellacci, M. Stipcevic, P. Strolin, S. Takahashi, M. Tenti, F. Terranova, V. Tioukov, S. Vasina, P. Vilain, E. Voevodina, L. Votano, J. L. Vuilleumier, G. Wilquet, B. Wonsak, and C. S. Yoon

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Section Analysis, line 9: sub-sample of 818 events becomes sub-sample of 817 events.

Published
2018
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13. Immunological and biochemical parameters of patients with metabolic syndrome and the participation of oxidative and nitroactive stress

Author

A.N.C. Simão, M.A.B. Lozovoy, T.N.C. Simão, D. Venturini, D.S. Barbosa, J.B. Dichi, T. Matsuo, R. Cecchini, and I. Dichi

Subjects
Metabolic syndrome, Uric acid, Inflammation, Adiponectin, Nitric oxide, Lipoperoxidation, Medicine (General), R5-920, Biology (General), QH301-705.5
Abstract

Metabolic syndrome (MS) is a multifactorial disease involving inflammatory activity and endothelial dysfunction. The aim of the present study was to evaluate the relationship between the changes in lipoperoxidation, in immunological and biochemical parameters and nitric oxide metabolite (NOx) levels in MS patients. Fifty patients with MS (4 males/46 females) and 50 controls (3 males/47 females) were studied. Compared to control (Mann-Whitney test), MS patients presented higher serum levels (P < 0.05) of fibrinogen: 314 (185-489) vs 262 (188-314) mg/dL, C-reactive protein (CRP): 7.80 (1.10-46.50) vs 0.70 (0.16-5.20) mg/dL, interleukin-6: 3.96 (3.04-28.18) vs 3.33 (2.55-9.63) pg/mL, uric acid: 5.45 (3.15-9.65) vs 3.81 (2.70-5.90) mg/dL, and hydroperoxides: 20,689 (19,076-67,182) vs 18,636 (15,926-19,731) cpm. In contrast, they presented lower (P < 0.05) adiponectin: 7.11 (3.19-18.22) vs 12.31 (9.11-27.27) µg/mL, and NOx levels: 5.69 (2.36-8.18) vs 6.72 (5.14-12.43) µM. NOx was inversely associated (Spearman’s rank correlation) with body mass index (r = -0.2858, P = 0.0191), insulin resistance determined by the homeostasis model assessment (r = -0.2530, P = 0.0315), CRP (r = -0.2843, P = 0.0171) and fibrinogen (r = -0.2464, P = 0.0413), and positively correlated with hydroperoxides (r = 0.2506, P = 0.0408). In conclusion, NOx levels are associated with obesity, insulin resistance, oxidative stress, and inflammatory markers. The high uric acid levels together with reactive oxygen species generation may be responsible for the reduced NO levels, which in turn lead to endothelial dysfunction. The elevated plasma chemiluminescence reflecting both increased plasma oxidation and reduced antioxidant capacity may play a role in the MS mechanism.

Published
2011
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14. The epidemiology of sepsis in a Brazilian teaching hospital

Author

I.A.M. Kauss, Cintia M.C. Grion, L.T.Q. Cardoso, E.H.T. Anami, L.B. Nunes, G.L. Ferreira, T. Matsuo, and A.M. Bonametti

Subjects
Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502
Abstract

Objectives: The objective of this study was to estimate disease incidence and mortality rate of sepsis in a tertiary public hospital. Methods: Patients admitted to the Intensive Care Unit (ICU) in 2004 and 2005 were monitored for sepsis using an observational longitudinal study design. Patients were monitored daily for diagnostic criteria of sepsis, according to ACCP/SCCM Consensus Conference criteria, until either death or hospital discharge. Results: During the study, we analyzed 1,179 patients. Systemic Inflammatory Response Syndrome (SIRS) was present in 1,048 (88.9%) patients on admission, and was associated with infection in 554 (47.0%) patients. Of these, sepsis was diagnosed in 30 (2.5%) patients, while severe sepsis was diagnosed in 269 (22.8%) patients, and septic shock was diagnosed in 255 (21.6%) patients. APACHE II and SOFA scores were higher in septic patients (p < 0.001), and the ensuing mortality rates were 32.8% (IC 95%: 21.6-45.7%) for patients with sepsis, 49.9% (IC 95%: 44.5-55.2%) for severe sepsis, and 72.7% (IC 95%: 68.1-76.9%) for septic shock. Conclusions: The data from our study revealed a high incidence of sepsis among hospitalized patients. Moreover, sepsis patients had a high rate of mortality. Keywords: sepsis, incidence, mortality, epidemiology

Published
2010
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15. Towards understanding the electrodynamics of the 3-dimensional high-latitude ionosphere: present and future

Author

O. Amm, A. Aruliah, S. C. Buchert, R. Fujii, J. W. Gjerloev, A. Ieda, T. Matsuo, C. Stolle, H. Vanhamäki, and A. Yoshikawa

Subjects
Science, Physics, QC1-999, Geophysics. Cosmic physics, QC801-809
Abstract

Traditionally, due to observational constraints, ionospheric modelling and data analysis techniques have been devised either in one dimension (e.g. along a single radar beam), or in two dimensions (e.g. over a network of magnetometers). With new upcoming missions like the Swarm ionospheric multi-satellite project, or the EISCAT 3-D project, the time has come to take into account variations in all three dimensions simultaneously, as they occur in the real ionosphere. The link between ionospheric electrodynamics and the neutral atmosphere circulation which has gained increasing interest in the recent years also intrinsically requires a truly 3-dimensional (3-D) description. In this paper, we identify five major science questions that need to be addressed by 3-D ionospheric modelling and data analysis. We briefly review what proceedings in the young field of 3-D ionospheric electrodynamics have been made in the past to address these selected question, and we outline how these issues can be addressed in the future with additional observations and/or improved data analysis and simulation techniques. Throughout the paper, we limit the discussion to high-latitude and mesoscale ionospheric electrodynamics, and to directly data-driven (not statistical) data analysis.

Published
2008
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16. Efficient methods for macroscopic magnetization simulation described by the assembly of simplified domain structure models

Author

T. Matsuo, T. Nakamura, S. Ito, T. Mifune, and C. Kaido

Subjects
magnetization, Physics, QC1-999, Electricity and magnetism, QC501-766
Abstract

This article presents two methods for the fast computation of macroscopic magnetization model called assembled domain structure model. First, an efficient method for computing the demagnetizing field is proposed. Secondly, a direct searching method of equilibrium point is developed, which greatly reduces the computation time.

Published
2015
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17. Immune and hormonal activity in adults suffering from depression

Author

S.O.V. Nunes, E.M.V. Reiche, H.K. Morimoto, T. Matsuo, E.N. Itano, E.C.D. Xavier, C.M. Yamashita, V.R. Vieira, A.V. Menoli, S.S. Silva, F.B. Costa, F.V. Reiche, F.L.V. Silva, and M.S. Kaminami

Subjects
Depression, Immunity, Psychoneuroimmunology, Cytokines, Acute phase proteins, Medicine (General), R5-920, Biology (General), QH301-705.5
Abstract

An association between depression and altered immune and hormonal systems has been suggested by the results of many studies. In the present study we carried out immune and hormonal measurements in 40 non-medicated, ambulatory adult patients with depression determined by CID-10 criteria and compared with 34 healthy nondepressed subjects. The severity of the condition was determined with the Hamilton Depression Rating Scale. Of 40 depressed patients, 31 had very severe and 9 severe or moderate depression, 29 (72.5%) were females and 11 (27.5%) were males (2.6:1 ratio). The results revealed a significant reduction of albumin and elevation of alpha-1, alpha-2 and ß-globulins, and soluble IL-2 receptor in patients with depression compared to the values obtained for nondepressed subjects (P

Published
2002
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19. Extreme Poleward Expanding Super Plasma Bubbles Over Asia-Pacific Region Triggered By Tonga Volcano Eruption During the Recovery-Phase of Geomagnetic Storm

Author

P. K. Rajesh, C. C. H. Lin, J.T. Lin, C. Y. Lin, J. Y. Liu, T. Matsuo, C. Y. Huang, M. Y. Chou, J. Yue, M. Nishioka, H. Jin, J.M. Choi, S.P. Chen, Marty Chou, and H. F. Tsai

Subjects
Space Sciences (General)
Abstract

The Tonga volcano eruption of 15 January 2022 unleashed a variety of atmospheric perturbations, coinciding with the recovery-phase of a geomagnetic storm. The ensuing thermospheric variations created rare display of extreme poleward-expanding conjugate plasma bubbles seen in the rate of total electron content index over 100–150°E, reaching ∼40°N geographic latitude. This is associated with fluctuations in FORMOSAT-7/COSMIC-2 (F7/C2) ion-density measurements and spread-F in ionograms. Preceding to this, an unusually strong pre-reversal enhancement (PRE) occurred in the global ionospheric specification (GIS) electron density profiles derived from F7/C2 observations. The GIS also revealed a decrease of equatorial ionization anomaly (EIA) crest density due to the storm impact. Reduced E-region conductivity by volcano-induced waves and enhanced F-region wind, further accelerated by reduced ion-drag over the EIA, apparently intensified the PRE. Accompanied with the strong PRE, volcano-induced seed perturbations triggered the super plasma bubble activity.

Published
2022
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22. OGLE-2013-BLG-0911Lb: A Secondary on the Brown-dwarf Planet Boundary around an M Dwarf

Author

Shota Miyazaki, Takahiro Sumi, David P. Bennett, Andrzej Udalski, Yossi Shvartzvald, Rachel Street, Valerio Bozza, Jennifer C. Yee, Ian A. Bond, Nicholas Rattenbury, Naoki Koshimoto, Daisuke Suzuki, Akihiko Fukui, F. Abe, A. Bhattacharya, R. Barry, M. Donachie, H. Fujii, Y. Hirao, Y. Itow, Y. Kamei, I. Kondo, M. C. A. Li, C. H. Ling, Y. Matsubara, T. Matsuo, Y. Muraki, M. Nagakane, K. Ohnishi, C Ranc, T. Saito1, A. Sharan, H. Shibai, H. Suematsu, D. J. Sullivan, P. J. Tristram, T. Yamakawa, A. Yonehara, J. Skowron, R. Poleski, P. Mróz, M. K. Szymański, I. Soszyński, P. Pietrukowicz, S. KozŁowski, K. Ulaczyk, Ł. Wyrzykowski, Matan Friedmann, Shai Kaspi, Dan Maoz, M. Albrow, G. Christie, D. L. DePoy, A. Gal-Yam, A. Gould, C.-U. Lee, I. Manulis, J. McCormick, T. Natusch, H. Ngan, R. W. Pogge, I. Porritt, Y. Tsapras, E. Bachelet, M. P. G. Hundertmark, M. Dominik, D. M. Bramich, A. Cassan, R. Figuera Jaimes, K. Horne, R. Schmidt, C. Snodgrass, J. Wambsganss, I. A. Steele, J. Menzies, S. Mao, U. G. Jørgensen, M. J. Burgdorf, S. Ciceri, S. Calchi Novati, G. D’Ago, D. F. Evans, T. C. Hinse, N. Kains, E. Kerins, H. Korhonen, L. Mancini, A. Popovas, M. Rabus, S. Rahvar, G. Scarpetta, J. Skottfelt, J. Southworth, N. Peixinho, and P. Verma

Subjects
Astrophysics, Astronomy
Abstract

We present the analysis of the binary-lens microlensing event OGLE-2013-BLG-0911. The best-fit solutions indicate the binary mass ratio of q 0.03, which differs from that reported in Shvartzvald et al. The event suffers from the well-known close/wide degeneracy, resulting in two groups of solutions for the projected separation normalized by the Einstein radius of s ~ 0.15 or s ~ 7. The finite source and the parallax observations allow us to measure the lens physical parameters. The lens system is an M dwarf orbited by a massive Jupiter companion at very close (M(host) = 0.30(sup +0.08, sub -0.06)Mʘ, M(comp) = 10.1 (sup +2.9, sub -2.2 M(jup), a(exp) = 0.40 (sup +0.05, sub -0.40)au) or wide (M(host) = 0.28 (sup +0.10, sub -0.80)Mʘ, M(comp) = 9.9 (sup +3.8, sub -3.5)M(jup), a(exp) = 18.0 (sup +3.2, sub -3.2)au) separation. Although the mass ratio is slightly above the planet-brown dwarf (BD) mass-ratio boundary of q = 0.03, which is generally used, the median physical mass of the companion is slightly below the planet-BD mass boundary of 13M(Jup). It is likely that the formation mechanisms for BDs and planets are different and the objects near the boundaries could have been formed by either mechanism. It is important to probe the distribution of such companions with masses of ~13M(Jup) in order to statistically constrain the formation theories for both BDs and massive planets. In particular, the microlensing method is able to probe the distribution around low-mass M dwarfs and even BDs, which is challenging for other exoplanet detection methods.

Published
2020
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25. MOA-bin-29b: A Microlensing Gas-giant Planet Orbiting a Low-mass Host Star

Author

Iona Kondo, Takahiro Sumi, David P Bennett, Andrzej Udalski, Ian A. Bond, Nicholas J. Rattenbury, Valerio Bozza, Yuki Hirao, Daisuke Suzuki, Naoki Koshimoto, Masayuki Nagakane, Shota Miyazaki, F. Abe, R Barry, A. Bhattacharya, M. Donachie, A. Fukui, H. Fujii, Y. Itow, Y. Kamei, M. C. A. Li, Y. Matsubara, T. Matsuo, Y. Muraki, Clement Ranc, H. Shibai, H. Suematsu, D. J. Sullivan, P. J. Tristram, T. Yamakawa, A. Yonehara, P. Mroz, M. K. Szymański, I. Soszyński, and and K. Ulaczyk

Subjects
Astrophysics, Astronomy
Abstract

We report the discovery of a gas-giant planet orbiting a low-mass host star in the microlensing event MOA-bin-29 that occurred in 2006. We find five degenerate solutions with the planet/host-star mass ratio of q ∼ 10(exp−2). The Einstein radius crossing time of all models are relatively short (∼4–7 days), which indicates that the mass of host star is likely low. The measured lens-source proper motion is 5–9 mas/yr depending on the models. Since only finite source effects are detected, we conduct a Bayesian analysis in order to obtain the posterior probability distribution of the lens physical properties. As a result, we find the lens system is likely to be a gas-giant orbiting a brown dwarf or a very late M-dwarf in the Galactic bulge. The probability distributions of the physical parameters for the five degenerate models are consistent within the range of error. By combining these probability distributions, we conclude that the lens system is a gas giant with a mass of M(p)= 0.63(sub +1.13, sub 0.39) M(Jup) orbiting a brown dwarf with a mass of M(h)= 0.06 (sup +0.11, sub -0.04) M(ʘ) at a projected star–planet separation of r⊥ = 0.53(sup +0.89, sub -0.18)au . The lens distance is D(L)= 6.89(sup +1.19, sub -1.19) kpc, i.e., likely within the Galactic bulge.

Published
2019
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26. OGLE-2015-BLG-1649Lb: A Gas Giant Planet around a Low-mass Dwarf

Author

M. Nagakane, Chien-Hsiu Lee, N. Koshimoto, Daisuke Suzuki, A. Udalski, J. P. Beaulieu, T. Sumi, D. P. Bennett, I. A. Bond, N. Rattenbury, E. Bachelet, Martin Dominik, F. Abe, R. K. Barry, A. Bhattacharya, M. Donachie, H. Fujii, A. Fukui, Y. Hirao, Y Itow, Y. Kamei, Iona Kondo, M. C. A. Li, Y. Matsubara, T. Matsuo, Shota Miyazaki, Y. Muraki, C. Ranc, H. Shibai, H. Suematsu, D. J. Sullivan, P. J. Tristram, T. Yamakawa, A. Yonehara, Przemek Mroz, Radoslaw Poleski, J. Skowron, M. K. Szymański, I. Soszyński, Pawel Pietrukowicz, Szymon Kozłowski, Krzysztof Ulaczyk, D. M. Bramich, A. Cassan, R. Figuera Jaimes, K. Horne, M. Hundertmark, Shude Mao, J. Menzies, R. Schmidt, Colin Snodgrass, Iain Steele, Rachel Street, Yiannis Tsapras, Joachim Wambsganss, U. G. Jørgensen, Valerio Bozza, P. Longã, Nuno Peixinho, J. Skottfelt, J. Southworth, M. I. Andersen, M. J. Burgdorf, Giuseppe D'Ago, Daniel Evans, Tobias Cornelius Hinse, H. Korhonen, Markus Rabus, and Sohrab Rahvar

Subjects
Astronomy, Astrophysics
Abstract

We report the discovery of an exoplanet from the analysis of the gravitational microlensing event OGLE-2015-BLG-1649 that challenges the core accretion model of planet formation and appears to support the disk instability model. The planet/host-star mass ratio is q = 7.2 × 10^(−3) and the projected separation normalized to the angular Einstein radius is s = 0.9. We conducted high-resolution follow-up observations using the Infrared Camera and Spectrograph (IRCS) camera on the Subaru telescope and are able to place an upper limit on the lens flux. From these measurements we are able to exclude all host stars greater than or equal in mass to a G-type dwarf. We conducted a Bayesian analysis with these new flux constraints included as priors resulting in estimates of the masses of the host star and planet. These are ML = 0.34 ± 0.19 M⊙ and M(p)=2.5 (+1.5,-1.4) M(Jup), respectively. The distance to the system is D(L)=4.23 (+1.51, -1.64) kpc. The projected star–planet separation is a(┴)=2.07 (+0.65,-0.77) au. The estimated relative lens-source proper motion, ~7.1 mas/yr, is fairly high and thus the lens can be better constrained if additional follow-up observations are conducted several years after the event.

Published
2019
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29. Carbamoylation of Azomethine Imines via Visible-Light Photoredox Catalysis

Author

Bianca T. Matsuo, Pedro H. R. Oliveira, José Tiago M Correia, and Márcio W. Paixão

Subjects
chemistry.chemical_classification, Chemistry, Organic Chemistry, Imine, Photoredox catalysis, Biochemistry, Combinatorial chemistry, Amino acid, chemistry.chemical_compound, Amide, Functional group, Photocatalysis, Molecule, Physical and Theoretical Chemistry, Visible spectrum
Abstract

A versatile and robust photocatalytic methodology to install the amide functional group into azomethine imine ions is described. This protocol is distinguished by its broad scope and mild reaction conditions, which are well suited for the preparation of structurally complex compounds in the form of amino acids, peptides, and small drug-like molecules. Moreover, the generated pyrazolidinone core could be easily converted into β-alanine analogues.

Published
2021
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30. OPERA tau neutrino charged current interactions

Author

A. Iuliano, S. Simone, S. Vasina, J. L. Vuilleumier, K. Ozaki, T. Fukuda, Chiara Sirignano, M. T. Muciaccia, L. Stanco, A. Sotnikov, Gaston Wilquet, M. Nakamura, G. Sirri, Artem Chukanov, D. A. Podgrudkov, J. Goldberg, Osamu Sato, Adele Lauria, Nicola D'Ambrosio, N. G. Polukhina, N. Di Marco, Antonio Ereditato, J. Ebert, Tatsuhiro Naka, R. Brugnera, A. Garfagnini, B. Klicek, Giuliana Galati, M. Spinetti, T. M. Roganova, N. Mauri, M. Chernyavskiy, G. Grella, A. M. Anokhina, Alessandro Paoloni, Masahiro Komatsu, C. S. Yoon, E. Shibayama, Toshiyuki Nakano, F. Mizutani, F. Pupilli, G. De Lellis, M. Tenti, Maria Cristina Montesi, Tomoko Ariga, M. De Serio, P. F. Loverre, S. Tufanli, D. Duchesneau, Akitaka Ariga, I. Tsanaktsidis, Kunihiro Morishima, C. Kamiscioglu, N. Agafonova, Shigeki Aoki, Seok Kim, S. Gorbunov, M. Pozzato, P. Monacelli, V. A. Matveev, Timur Dzhatdoev, Cristiano Bozza, Y. A. Gornushkin, N. M. Okateva, Nobuko Kitagawa, Krešimir Jakovčić, A. Lavasa, A. Longhin, Utku Kose, V. Gentile, L. Pasqualini, T. Shiraishi, A. Hollnagel, L. Patrizii, Satoru Takahashi, G. Mandrioli, A. Schembri, A. Buonaura, Gianfranca De Rosa, S. Dusini, T. Matsuo, C. Gustavino, T. Hayakawa, N. I. Starkov, Salvatore Buontempo, Anselmo Meregaglia, T. V. Shchedrina, Pierre Vilain, Andrey Ustyuzhanin, S. Ogawa, A. M. Guler, A. Alexandrov, S. Dmitrievsky, B. D. Park, Naotaka Naganawa, M. Roda, P. Strolin, Marcos Dracos, Motoaki Miyanishi, O. G. Ryazhskaya, R. A. Fini, E. Medinaceli, Hiroki Rokujo, Simona Maria Stellacci, A. S. Malgin, I. Shakirianova, Alessandro Pastore, F. Fornari, Mario Stipčević, D. Di Ferdinando, Katsumi Ishiguro, S. Mikado, I. Kreslo, M. Vidal García, A. Di Crescenzo, H. Pessard, T. Šimko, P. Del Amo Sanchez, V. Tioukov, K. Kodama, Caren Hagner, T. Hara, L. Consiglio, F. Terranova, A. Bertolin, Kimio Niwa, H. Shibuya, E. Voevodina, M. Kamiscioglu, Cécile Jollet, L. Votano, F. Laudisio, Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), OPERA, Agafonova, N, Alexandrov, A, Anokhina, A, Aoki, S, Ariga, A, Ariga, T, Bertolin, A, Bozza, C, Brugnera, R, Buonaura, A, Buontempo, S, Chernyavskiy, M, Chukanov, A, Consiglio, L, D'Ambrosio, N, De Lellis, G, De Serio, M, del Amo Sanchez, P, Di Crescenzo, A, Di Ferdinando, D, Di Marco, N, Dmitrievsky, S, Dracos, M, Duchesneau, D, Dusini, S, Dzhatdoev, T, Ebert, J, Ereditato, A, Fini, R, Fornari, F, Fukuda, T, Galati, G, Garfagnini, A, Gentile, V, Goldberg, J, Gorbunov, S, Gornushkin, Y, Grella, G, Guler, A, Gustavino, C, Hagner, C, Hara, T, Hayakawa, T, Hollnagel, A, Ishiguro, K, Iuliano, A, Jakovcic, K, Jollet, C, Kamiscioglu, C, Kamiscioglu, M, Kim, S, Kitagawa, N, Klicek, B, Kodama, K, Komatsu, M, Kose, U, Kreslo, I, Laudisio, F, Lauria, A, Lavasa, A, Longhin, A, Loverre, P, Malgin, A, Mandrioli, G, Matsuo, T, Matveev, V, Mauri, N, Medinaceli, E, Meregaglia, A, Mikado, S, Miyanishi, M, Mizutani, F, Monacelli, P, Montesi, M, Morishima, K, Muciaccia, M, Naganawa, N, Naka, T, Nakamura, M, Nakano, T, Niwa, K, Ogawa, S, Okateva, N, Ozaki, K, Paoloni, A, Park, B, Pasqualini, L, Pastore, A, Patrizii, L, Pessard, H, Podgrudkov, D, Polukhina, N, Pozzato, M, Pupilli, F, Roda, M, Roganova, T, Rokujo, H, Rosa, G, Ryazhskaya, O, Sato, O, Shakirianova, I, Schembri, A, Shchedrina, T, Shibayama, E, Shibuya, H, Shiraishi, T, Simko, T, Simone, S, Sirignano, C, Sirri, G, Sotnikov, A, Spinetti, M, Stanco, L, Starkov, N, Stellacci, S, Stipcevic, M, Strolin, P, Takahashi, S, Tenti, M, Terranova, F, Tioukov, V, Tsanaktsidis, I, Tufanli, S, Ustyuzhanin, A, Vasina, S, Vidal Garcia, M, Vilain, P, Voevodina, E, Votano, L, Vuilleumier, J, Wilquet, G, Yoon, C, Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., del Amo Sanchez, P., Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gorbunov, S., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Lavasa, A., Longhin, A., Loverre, P., Malgin, A., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Ogawa, S., Okateva, N., Ozaki, K., Paoloni, A., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Shakirianova, I., Schembri, A., Shchedrina, T., Shibayama, E., Shibuya, H., Shiraishi, T., Simko, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tsanaktsidis, I., Tufanli, S., Ustyuzhanin, A., Vasina, S., Vidal Garcia, M., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., Yoon, C. S., Agafonova N., Alexandrov A., Anokhina A., Aoki S., Ariga A., Ariga T., Bertolin A., Bozza C., Brugnera R., Buonaura A., Buontempo S., Chernyavskiy M., Chukanov A., Consiglio L., D'Ambrosio N., De Lellis G., De Serio M., del Amo Sanchez P., Di Crescenzo A., Di Ferdinando D., Di Marco N., Dmitrievsky S., Dracos M., Duchesneau D., Dusini S., Dzhatdoev T., Ebert J., Ereditato A., Fini R.A., Fornari F., Fukuda T., Galati G., Garfagnini A., Gentile V., Goldberg J., Gorbunov S., Gornushkin Y., Grella G., Guler A.M., Gustavino C., Hagner C., Hara T., Hayakawa T., Hollnagel A., Ishiguro K., Iuliano A., Jakovcic K., Jollet C., Kamiscioglu C., Kamiscioglu M., Kim S.H., Kitagawa N., Klicek B., Kodama K., Komatsu M., Kose U., Kreslo I., Laudisio F., Lauria A., Lavasa A., Longhin A., Loverre P., Malgin A., Mandrioli G., Matsuo T., Matveev V., Mauri N., Medinaceli E., Meregaglia A., Mikado S., Miyanishi M., Mizutani F., Monacelli P., Montesi M.C., Morishima K., Muciaccia M.T., Naganawa N., Naka T., Nakamura M., Nakano T., Niwa K., Ogawa S., Okateva N., Ozaki K., Paoloni A., Park B.D., Pasqualini L., Pastore A., Patrizii L., Pessard H., Podgrudkov D., Polukhina N., Pozzato M., Pupilli F., Roda M., Roganova T., Rokujo H., Rosa G., Ryazhskaya O., Sato O., Shakirianova I., Schembri A., Shchedrina T., Shibayama E., Shibuya H., Shiraishi T., Simko T., Simone S., Sirignano C., Sirri G., Sotnikov A., Spinetti M., Stanco L., Starkov N., Stellacci S.M., Stipcevic M., Strolin P., Takahashi S., Tenti M., Terranova F., Tioukov V., Tsanaktsidis I., Tufanli S., Ustyuzhanin A., Vasina S., Vidal Garcia M., Vilain P., Voevodina E., Votano L., Vuilleumier J.L., Wilquet G., and Yoon C.S.

Subjects
Statistics and Probability, Data Descriptor, Particle physics, data analysis method, CERN Lab, lead: target, Opera, Science, Library and Information Sciences, 7. Clean energy, 01 natural sciences, OPERA, neutrino oscillation, dataset, Education, charged current, CNGS, Tau neutrino, 0103 physical sciences, tau neutrino, neutrino detector, OPERA, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], 010306 general physics, Neutrino oscillation, neutrino, tau appearance, Charged current, nuclear-emulsion, energy, ratio, Physics, Large Hadron Collider, 010308 nuclear & particles physics, nucleus, neutrino nucleus: interaction, neutrino/mu: secondary beam, Computer Science Applications, Gran Sasso, neutrino/tau: particle identification, Phenomenology, neutrino: oscillation, Statistics, Probability and Uncertainty, Experimental particle physics, statistical, Beam (structure), Particle Physics - Experiment, Information Systems, experimental results
Abstract

The OPERA experiment was designed to discover the vτ appearance in a vμ beam, due to neutrino oscillations. The detector, located in the underground Gran Sasso Laboratory, consisted of a nuclear photographic emulsion/lead target with a mass of about 1.25 kt, complemented by electronic detectors. It was exposed from 2008 to 2012 to the CNGS beam: an almost pure vμ beam with a baseline of 730 km, collecting a total of 1.8·1020 protons on target. The OPERA Collaboration eventually assessed the discovery of vμ→vτ oscillations with a statistical significance of 6.1 σ by observing ten vτ CC interaction candidates. These events have been published on the Open Data Portal at CERN. This paper provides a detailed description of the vτ data sample to make it usable by the whole community., Measurement(s)tau neutrinoTechnology Type(s)detectorSample Characteristic - Environmentneutrino beamSample Characteristic - LocationLaboratori Nazionali del Gran Sasso Machine-accessible metadata file describing the reported data: 10.6084/m9.figshare.14979858

Published
2021
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31. Photoinduced carbamoylation reactions: unlocking new reactivities towards amide synthesis

Author

Bianca T. Matsuo, Pedro H. R. Oliveira, Emanuele F. Pissinati, Kimberly B. Vega, Iva S. de Jesus, Jose Tiago M. Correia, and Márcio Paixao

Subjects
Protein Carbamylation, Formamides, Materials Chemistry, Metals and Alloys, Ceramics and Composites, General Chemistry, Chemistry Techniques, Synthetic, Amides, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials
Abstract

The preparation of amide-containing compounds is among the most interesting and challenging topics for the synthetic community. Such relevance is given by their reactive aspects explored in the context of organic synthesis and by the direct application of these compounds as pharmaceuticals and useful materials, and their key roles in biological structures. A simple and straightforward strategy for the amide moiety installation is the use of carbamoyl radicals - this nucleophilic one-electron intermediate is prone to undergo a series of transformations, providing a range of structurally relevant derivatives. In this review, we summarize the latest advances in the field from the perspective of photoinduced protocols. To this end, their synthetic applications are organized accordingly to the nature of the radical precursor (formamides through HAT, 4-substituted-1,4-dihydropyridines, oxamic acids, and

Published
2022

34. Visible-Light-Mediated α-Amino Alkylation of Azomethine Imines: An Approach to N-(β-Aminoalkyl)pyrazolidinones

Author

Márcio W. Paixão, José Tiago M Correia, and Bianca T. Matsuo

Subjects
chemistry.chemical_compound, Chemistry, Organic Chemistry, Functional group, Photocatalysis, Moiety, Iminium, Physical and Theoretical Chemistry, Alkylation, Biochemistry, Combinatorial chemistry, Visible spectrum
Abstract

Herein, a mild and robust photocatalytic protocol for the combination of amino and pyrazolidinone functionalities through a radical α-amino alkylation of azomethine iminium ions is demonstrated. This method presents a high functional group tolerance providing direct access to a large family of N-(β-aminoalkyl)pyrazolidinones in good to excellent yields, including the late-stage incorporation of the pyrazolidinone moiety to pharmaceutical ingredients. We propose a plausible scenario for the C-C bond-forming step which involves radical addition followed by a spin-center-shift event.

Published
2020
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35. Photoinduced deaminative strategies: Katritzky salts as alkyl radical precursors

Author

Wanderson C de Souza, José A C Delgado, Márcio W. Paixão, José Tiago M Correia, Bianca T. Matsuo, and Vitor A. Fernandes

Subjects
chemistry.chemical_classification, Primary (chemistry), Bioactive molecules, Metals and Alloys, General Chemistry, Combinatorial chemistry, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Organic molecules, chemistry.chemical_compound, chemistry, Materials Chemistry, Ceramics and Composites, Organic synthesis, Alkyl
Abstract

Primary amines are one of the most predominant functional groups found in organic molecules. These entities help form the chemical architecture of natural products, bioactive molecules, synthetic building blocks and catalysts. Due to their ubiquitous presence, the development of strategies for the construction of C-C or C-X bonds through deaminative processes is of high importance. Deaminative methods offer new possibilities on the retrosynthetic rationale, and enable late-stage-functionalization of complex structures. As a result of the recent development of photoinduced processes, a variety of photo-mediated deaminative protocols employing 2,4,6-triphenyl-pyridinium salts - Katritzky Salts - as activating agents have been recently realized. This review covers the most recent developments of deaminative strategies by using Katritzky Salts as alkyl radical reservoirs, with particular concern on photoinduced processes applied to organic synthesis.

Published
2020
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38. System for augmented human–robot interaction through mixed reality and robot training by non-experts in customer service environments

Author

T. Fukui, Akira Taniguchi, Y. Tabuchi, Shota Isobe, Yuki Katsumata, Yoshinobu Hagiwara, Tadahiro Taniguchi, T. Matsuo, Masaki Yamamoto, Gustavo Alfonso Garcia Ricardez, H. Nakamura, and L. El Hafi

Subjects
Service (business), 0209 industrial biotechnology, Computer science, Context (language use), Cognition, 02 engineering and technology, Training (civil), Human–robot interaction, Mixed reality, Computer Science Applications, Human-Computer Interaction, 020901 industrial engineering & automation, Hardware and Architecture, Control and Systems Engineering, Human–computer interaction, 0202 electrical engineering, electronic engineering, information engineering, Robot, Customer service, 020201 artificial intelligence & image processing, Software
Abstract

Human–robot interaction during general service tasks in home or retail environment has been proven challenging, partly because (1) robots lack high-level context-based cognition and (2) humans cann...

Published
2019
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39. Synthesis of (Z)-β-halo α,β-unsaturated carbonyl systems via the combination of halotrimethylsilane and tetrafluoroboric acid

Author

Akbar Ali, Márcio W. Paixão, Bianca T. Matsuo, Gustavo P. da Silva, Vitor A F da Silva, Julio Zukerman-Schpector, Arlene G. Corrêa, and Rebecca L. Davis

Subjects
010405 organic chemistry, Chemistry, Organic Chemistry, 010402 general chemistry, Hydrohalogenation, 01 natural sciences, Biochemistry, Medicinal chemistry, 0104 chemical sciences, 3. Good health, Solvent, Stereoselectivity, Lewis acids and bases, Physical and Theoretical Chemistry, Brønsted–Lowry acid–base theory
Abstract

A convenient and broadly applicable method for the hydrohalogenation of ynones is described, by the combination of halotrimethylsilanes and tetrafluoroboric acid. Practically, one equivalent of HX (Brønsted acid) and BF3 (Lewis acid) is smoothly generated, which activates the carbonyl compounds. Through this protocol, 42 examples of (Z)-β-halovinyl carbonyl compounds (Cl, Br and I) were obtained, in good yields and high stereoselectivity having 2-MeTHF as a solvent.

Published
2019
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40. First measurement using a nuclear emulsion detector of the charged-current cross section on iron around the 1 GeV energy region

Author

Naotaka Naganawa, Hiroki Rokujo, Ahmed Ali, K. Mizuno, Y. Hayato, S. Ogawa, T. Kikawa, Masashi Yokoyama, Satoru Takahashi, T. Takao, R. Watanabe, Tsuyoshi Nakaya, Kou Sugimura, Yosuke Suzuki, Haruka Matsumoto, Y. Morimoto, Y. Hanaoka, A. Hiramoto, Kenji Kuretsubo, Hiroaki Kawahara, L. Suzui, Masahiro Komatsu, T. Matsuo, Noboru Nakano, L. Berns, M. Nakamura, S. Mikado, R. Komatani, Y. Nakamura, Toshio Fukuda, Y. Tanihara, H. Takagi, M. Naiki, Osamu Sato, A. K. Ichikawa, Akira Nishio, T. Odagawa, H. Shibuya, Toshiyuki Nakano, Kunihiro Morishima, H. Oshima, K Yamada, Shigeki Aoki, K. Yasutome, A. Minamino, and Toshitsugu Marushima

Subjects
Physics, Muon, Physics::Instrumentation and Detectors, General Physics and Astronomy, Space (mathematics), High Energy Physics - Experiment, Cross section (physics), Nuclear emulsion, High Energy Physics::Experiment, Neutrino, Atomic physics, Nucleon, Nuclear Experiment, Charged current, Energy (signal processing)
Abstract

We have carried out $\nu_{\mu}$ charged-current interaction measurement on iron using an emulsion detector exposed to the T2K neutrino beam in the J-PARC neutrino facility. The data samples correspond to 4.0$\times$10$^{19}$ protons on target, and the neutrino mean energy is 1.49$\,$GeV. The emulsion detector is suitable for precision measurements of charged particles produced in neutrino-iron interactions with a low momentum threshold thanks to thin-layered structure and sub-$\mu$m spatial resolution. The charged particles are successfully detected, and their multiplicities are measured using the emulsion detector. The cross section was measured to be $\sigma^{\mathrm{Fe}}_{\mathrm{CC}} = (1.28 \pm 0.11({\mathrm{stat.}})^{+0.12}_{-0.11}({\mathrm{syst.}})) \times 10^{-38} \, {\mathrm{cm}}^{2}/{\mathrm{nucleon}}$. The cross section in a limited kinematic phase space of induced muons, $\theta_{\mu} < 45^{\circ}$ and $p_{\mu} > 400 \, {\rm MeV}/c$, on iron was $\sigma^{\mathrm{Fe}}_{\mathrm{CC \hspace{1mm} phase \hspace{0.5mm} space}} = (0.84 \pm 0.07({\mathrm{stat.}})^{+0.07}_{-0.06}({\mathrm{syst.}})) \times 10^{-38} \, {\mathrm{cm}}^{2}/{\mathrm{nucleon}}$. The cross-section results are consistent with previous values obtained via different techniques using the same beamline, and they are well reproduced by current neutrino interaction models. These results demonstrate the capability of the detector towards the detailed measurements of the neutrino-nucleus interactions around the 1$\,$GeV energy region., Comment: 27 pages, 17 figures

Published
2021

41. Ruptured aneurysm–induced pituitary apoplexy: illustrative case

Author

Yoshida M, Hiu T, Baba S, Morikawa M, Horie N, Ujifuku K, Yoshida K, Matsunaga Y, Niino D, Xie A, Izumo T, Anda T, Matsuo T., NIINO, Daisuke, Yoshida M, Hiu T, Baba S, Morikawa M, Horie N, Ujifuku K, Yoshida K, Matsunaga Y, Niino D, Xie A, Izumo T, Anda T, Matsuo T., and NIINO, Daisuke

Published
2021

42. First measurement of ν¯μ and νμ charged-current inclusive interactions on water using a nuclear emulsion detector

Author

T. Nakano, M. Naiki, Y. Hanaoka, A. K. Ichikawa, Kou Sugimura, Masashi Yokoyama, Tsuyoshi Nakaya, Hiroki Rokujo, Osamu Sato, L. Berns, T. Fukuda, M. Nakamura, T. Odagawa, A. Minamino, Naotaka Naganawa, Y. Hayato, Y. Nakamura, T. Koga, H. Takagi, Y. Tanihara, K. Mizuno, S. Ogawa, A. Ali, T. Kikawa, Akira Nishio, T. Matsuo, Noboru Nakano, Shigeki Aoki, Y. Kosakai, K. Yasutome, Yasunari Suzuki, Masahiro Komatsu, Hiroaki Kawahara, R. Komatani, H. Shibuya, L. Suzui, I. Sanjana, S. Mikado, Kunihiro Morishima, T. Takao, H. Oshima, A. Hiramoto, and Y. Morimoto

Subjects
Nuclear physics, Physics, Muon, Pion, Physics::Instrumentation and Detectors, Nuclear Theory, Detector, High Energy Physics::Experiment, Nuclear emulsion, Multiplicity (chemistry), Neutrino, Nuclear Experiment, Charged current
Abstract

This paper reports the track multiplicity and kinematics of muons, charged pions, and protons from charged-current inclusive $\bar{\nu}_{\mu}$ and $\nu_{\mu}$ interactions on a water target, measured using a nuclear emulsion detector in the NINJA experiment. A 3-kg water target was exposed to the T2K antineutrino-enhanced beam with a mean energy of 1.3 GeV. Owing to the high-granularity of the nuclear emulsion, protons with momenta down to 200 MeV/$c$ from the neutrino-water interactions were detected. We find good agreement between the observed data and model predictions for all kinematic distributions other than the number of charged pions. These results demonstrate the capability of measurements with nuclear emulsion to improve neutrino interaction models.

Published
2020
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44. Visible-Light-Mediated α-Amino Alkylation of Azomethine Imines: An Approach to

Author

Bianca T, Matsuo, José Tiago M, Correia, and Márcio W, Paixão

Abstract

Herein, a mild and robust photocatalytic protocol for the combination of amino and pyrazolidinone functionalities through a radical α-amino alkylation of azomethine iminium ions is demonstrated. This method presents a high functional group tolerance providing direct access to a large family of

Published
2020

45. First observation of a tau neutrino charged current interaction with charm production in the OPERA experiment

Author

G. De Lellis, C. Kamiscioglu, L. Votano, R. Brugnera, F. Laudisio, S. Gorbunov, F. Pupilli, A. Longhin, A. Buonaura, A. Garfagnini, Timur Dzhatdoev, Nicola D'Ambrosio, Tatsuhiro Naka, P. F. Loverre, Motoaki Miyanishi, P. Strolin, Alessandra Pastore, Marcos Dracos, Satoru Takahashi, E. Shibayama, Toshiyuki Nakano, M. Nakamura, M. Tenti, A. Schembri, Krešimir Jakovčić, L. Paparella, R. A. Fini, C. Gustavino, H. Shibuya, Gianfranca De Rosa, N. I. Starkov, D. Duchesneau, E. Voevodina, N. G. Polukhina, T. Hara, I. Kreslo, Seok Kim, Tomoko Ariga, M. De Serio, J. Ebert, M. Kamiscioglu, M. Pozzato, Kunihiro Morishima, T. Matsuo, N. Di Marco, T. Hayakawa, T. Fukuda, Cristiano Bozza, V. A. Matveev, N. M. Okateva, Naotaka Naganawa, A. Bertolin, Anselmo Meregaglia, V. Gentile, H. Pessard, Antonio Ereditato, M. Malenica, J. Goldberg, Osamu Sato, Adele Lauria, M. Roda, Cécile Jollet, Salvatore Buontempo, M. Spinetti, M. T. Muciaccia, E. Medinaceli, A. S. Malgin, L. Pasqualini, L. Patrizii, G. Mandrioli, G. Sirri, Artem Chukanov, D. A. Podgrudkov, S. Dmitrievski, T. V. Shchedrina, P. del Amo Sanchez, A. Iuliano, S. Simone, Chiara Sirignano, S. Dusini, Alessandro Paoloni, S. Vasina, Mario Stipčević, Katsumi Ishiguro, M. Chernyavskiy, F. Mizutani, I. Shakirianova, A. Di Crescenzo, N. Agafonova, Utku Kose, A. M. Guler, G. Grella, F. Fornari, B. Klicek, Giuliana Galati, J. L. Vuilleumier, K. Ozaki, V. Tioukov, T. Shiraishi, A. Sotnikov, Nobuko Kitagawa, Masahiro Komatsu, D. Di Ferdinando, O. G. Ryazhskaya, C. S. Yoon, Y. A. Gornushkin, Gaston Wilquet, S. Mikado, Maria Cristina Montesi, Hiroki Rokujo, Simona Maria Stellacci, Akitaka Ariga, Shigeki Aoki, L. Stanco, Pierre Vilain, A. Hollnagel, P. Monacelli, A. B. Aleksandrov, T. M. Roganova, N. Mauri, B. D. Park, A. M. Anokhina, Kimio Niwa, S. Ogawa, K. Kodama, Caren Hagner, L. Consiglio, F. Terranova, Agafonova N., Aleksandrov A., Anokhina A., Aoki S., Ariga A., Ariga T., Bertolin A., Bozza C., Brugnera R., Buonaura A., Buontempo S., Chernyavskiy M., Chukanov A., Consiglio L., D'Ambrosio N., De Lellis G., De Serio M., del AmoSanchez P., Di Crescenzo A., Di Ferdinando D., Di Marco N., Dmitrievski S., Dracos M., Duchesneau D., Dusini S., Dzhatdoev T., Ebert J., Ereditato A., Fini R.A., Fornari F., Fukuda T., Galati G., Garfagnini A., Gentile V., Goldberg J., Gorbunov S., Gornushkin Y., Grella G., Guler A.M., Gustavino C., Hagner C., Hara T., Hayakawa T., Hollnagel A., Ishiguro K., Iuliano A., Jakovcic K., Jollet C., Kamiscioglu C., Kamiscioglu M., Kim S.H., Kitagawa N., Klicek B., Kodama K., Komatsu M., Kose U., Kreslo I., Laudisio F., Lauria A., Longhin A., Loverre P., Malgin A., Malenica M., Mandrioli G., Matsuo T., Matveev V., Mauri N., Medinaceli E., Meregaglia A., Mikado S., Miyanishi M., Mizutani F., Monacelli P., Montesi M.C., Morishima K., Muciaccia M.T., Naganawa N., Naka T., Nakamura M., Nakano T., Niwa K., Okateva N., Ogawa S., Ozaki K., Paoloni A., Paparella L., Park B.D., Pasqualini L., Pastore A., Patrizii L., Pessard H., Podgrudkov D., Polukhina N., Pozzato M., Pupilli F., Roda M., Roganova T., Rokujo H., Rosa G., Ryazhskaya O., Sato O., Schembri A., Shakirianova I., Shchedrina T., Shibuya H., Shibayama E., Shiraishi T., Simone S., Sirignano C., Sirri G., Sotnikov A., Spinetti M., Stanco L., Starkov N., Stellacci S.M., Stipcevic M., Strolin P., Takahashi S., Tenti M., Terranova F., Tioukov V., Vasina S., Vilain P., Voevodina E., Votano L., Vuilleumier J.L., Wilquet G., Yoon C.S., Agafonova, N, Aleksandrov, A, Anokhina, A, Aoki, S, Ariga, A, Ariga, T, Bertolin, A, Bozza, C, Brugnera, R, Buonaura, A, Buontempo, S, Chernyavskiy, M, Chukanov, A, Consiglio, L, D'Ambrosio, N, De Lellis, G, De Serio, M, del AmoSanchez, P, Di Crescenzo, A, Di Ferdinando, D, Di Marco, N, Dmitrievski, S, Dracos, M, Duchesneau, D, Dusini, S, Dzhatdoev, T, Ebert, J, Ereditato, A, Fini, R, Fornari, F, Fukuda, T, Galati, G, Garfagnini, A, Gentile, V, Goldberg, J, Gorbunov, S, Gornushkin, Y, Grella, G, Guler, A, Gustavino, C, Hagner, C, Hara, T, Hayakawa, T, Hollnagel, A, Ishiguro, K, Iuliano, A, Jakovcic, K, Jollet, C, Kamiscioglu, C, Kamiscioglu, M, Kim, S, Kitagawa, N, Klicek, B, Kodama, K, Komatsu, M, Kose, U, Kreslo, I, Laudisio, F, Lauria, A, Longhin, A, Loverre, P, Malgin, A, Malenica, M, Mandrioli, G, Matsuo, T, Matveev, V, Mauri, N, Medinaceli, E, Meregaglia, A, Mikado, S, Miyanishi, M, Mizutani, F, Monacelli, P, Montesi, M, Morishima, K, Muciaccia, M, Naganawa, N, Naka, T, Nakamura, M, Nakano, T, Niwa, K, Okateva, N, Ogawa, S, Ozaki, K, Paoloni, A, Paparella, L, Park, B, Pasqualini, L, Pastore, A, Patrizii, L, Pessard, H, Podgrudkov, D, Polukhina, N, Pozzato, M, Pupilli, F, Roda, M, Roganova, T, Rokujo, H, Rosa, G, Ryazhskaya, O, Sato, O, Schembri, A, Shakirianova, I, Shchedrina, T, Shibuya, H, Shibayama, E, Shiraishi, T, Simone, S, Sirignano, C, Sirri, G, Sotnikov, A, Spinetti, M, Stanco, L, Starkov, N, Stellacci, S, Stipcevic, M, Strolin, P, Takahashi, S, Tenti, M, Terranova, F, Tioukov, V, Vasina, S, Vilain, P, Voevodina, E, Votano, L, Vuilleumier, J, Wilquet, G, and Yoon, C

Subjects
Physics, Particle physics, Physics and Astronomy (miscellaneous), Neutral current, 010308 nuclear & particles physics, tau neutrino interaction, charm production, OPERA, 01 natural sciences, neutrino, Pair production, Tau neutrino, 0103 physical sciences, High Energy Physics::Experiment, Production (computer science), Charm (quantum number), Neutrino, 010306 general physics, Engineering (miscellaneous), Event (particle physics), Charged current
Abstract

An event topology with two secondary vertices compatible with the decay of short-lived particles was found in the analysis of neutrino interactions in the OPERA target. The observed topology is compatible with tau neutrino charged current (CC) interactions with charm production and neutrino neutral current (NC) interactions with $$c\overline{c}$$cc¯ pair production. However, other processes can mimic this topology. A dedicated analysis was implemented to identify the underlying process. A Monte Carlo simulation was developed and complementary procedures were introduced in the kinematic reconstruction. A multivariate analysis technique was used to achieve an optimal separation of signal from background. Most likely, this event is a $$\nu _{\tau }$$ντ CC interaction with charm production, the tau and charm particle decaying into 1 prong and 2 prongs, respectively. The significance of this observation is evaluated.

Published
2020
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46. Relationship between preoperative nutritional status of transurethral lithotripsy and development of postoperative systemic inflammatory response syndrome

Author

Yasuyoshi Miyata, K. Mitsunari, A. Ohtsubo, K. Ohba, T. Matsuo, Y. Mukae, and Hideki Sakai

Subjects
medicine.medical_specialty, business.industry, Urology, medicine.medical_treatment, Nutritional status, Lithotripsy, medicine.disease, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Gastroenterology, lcsh:RC254-282, Systemic inflammatory response syndrome, Internal medicine, medicine, business
Published
2020

47. The anticancer effect of plant enzymes on mouse breast cancer model

Author

N Washino, KM Kang, T Yamasita, T Matsuo, H Yamamoto, DJ Choi, and YH Gu

Subjects
Marketing, Pharmacology, chemistry.chemical_classification, Organizational Behavior and Human Resource Management, Enzyme, chemistry, Strategy and Management, Drug Discovery, Cancer research, Pharmaceutical Science, Biology, Breast Cancer Model
Published
2018
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48. Organocatalyzed Asymmetric Vinylogous Addition of Oxazole-2(3H)-thiones to α,β-Unsaturated Ketones: An Additive-Free Approach for Diversification of Heterocyclic Scaffold

Author

Marco A. B. Ferreira, Sandrina I. R. M. Silva, Patrick Rollin, Márcio W. Paixão, Julio Zukerman-Schpector, R. Silva, Lucas V. Pozzi, Arlene G. Corrêa, and Bianca T. Matsuo

Subjects
chemistry.chemical_compound, 010405 organic chemistry, Chemistry, Organic Chemistry, Absolute configuration, Michael reaction, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, Catalysis, Adduct, Oxazole
Abstract

A straightforward organocatalyzed asymmetric addition of oxazole-2(3H)-thiones to α,β-unsaturated ketones is described. This additive-free Michael reaction in the presence of chiral cinchonine-derived primary amines as catalysts has proven to be highly effective for a wide range of cyclic and acyclic enones, leading to the Michael adducts in very good yields and excellent enantioselectivities. The absolute configuration (R) of compound 5j was unambiguously assigned by X-ray diffraction analysis. Furthermore, experimental and theoretical studies were performed and a mechanism is presented and discussed for this novel reaction.

Published
2018
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50. Pathological role of the prostaglandin E2-specific type E prostanoid receptors in hormone-sensitive and castration-resistant prostate cancer

Author

T. Matsuda, K. Mitsunari, J. Harada, K. Ohba, Yasuyoshi Miyata, T. Matsuo, Y. Mukae, A. Otsubo, and Hideki Sakai

Subjects
business.industry, Urology, Prostanoid, Castration resistant, medicine.disease, Hormone-sensitive, Prostate cancer, chemistry.chemical_compound, chemistry, Cancer research, medicine, Prostaglandin E2, business, Receptor, Pathological, medicine.drug
Published
2021
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