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188 results on '"Sung, Y. J."'

1. Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry

Author

de las Fuentes, L., Sung, Y. J., Sitlani, C. M., Avery, C. L., Bartz, T. M., Keyser, C. de, Evans, D. S., Li, X., Musani, S. K., Ruiter, R., Smith, A. V., Sun, F., Trompet, S., Xu, H., Arnett, D. K., Bis, J. C., Broeckel, U., Busch, E. L., Chen, Y.-D. I., Correa, A., Cummings, S. R., Floyd, J. S., Ford, I., Guo, X., Harris, T. B., Ikram, M. A., Lange, L., Launer, L. J., Reiner, A. P., Schwander, K., Smith, N. L., Sotoodehnia, N., Stewart, J. D., Stott, D. J., Stürmer, T., Taylor, K. D., Uitterlinden, A., Vasan, R. S., Wiggins, K. L., Cupples, L. A., Gudnason, V., Heckbert, S. R., Jukema, J. W., Liu, Y., Psaty, B. M., Rao, D. C., Rotter, J. I., Stricker, B., Wilson, J. G., and Whitsel, E. A.

Published
2020
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4. Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

Author

Natarajan, P. (Pradeep), Pampana, A. (Akhil), Graham, S. E. (Sarah E.), Ruotsalainen, S. E. (Sanni E.), Perry, J. A. (James A.), de Vries, P. S. (Paul S.), Broome, J. G. (Jai G.), Pirruccello, J. P. (James P.), Honigbere, M. C. (Michael C.), Aragam, K. (Krishna), Wolford, B. (Brooke), Brody, J. A. (Jennifer A.), Antonacci-Fulton, L. (Lucinda), Arden, M. (Moscati), Aslibekyan, S. (Stella), Assimes, T. L. (Themistocles L.), Ballantyne, C. M. (Christie M.), Bielak, L. F. (Lawrence F.), Bisl, J. C. (Joshua C.), Cade, B. E. (Brian E.), Do, R. (Ron), Doddapaneni, H. (Harsha), Emery, L. S. (Leslie S.), Hung, Y.-J. (Yi-Jen), Irvin, M. R. (Marguerite R.), Khan, A. T. (Alyna T.), Lange, L. (Leslie), Lee, J. (Jiwon), Lemaitre, R. N. (Rozenn N.), Martin, L. W. (Lisa W.), Metcalf, G. (Ginger), Montasser, M. E. (May E.), Moon, J.-Y. (Jee-Young), Muzny, D. (Donna), Connell, J. R. (Jeffrey R. O.), Palmer, N. D. (Nicholette D.), Peralta, J. M. (Juan M.), Peyser, P. A. (Patricia A.), Stilp, A. M. (Adrienne M.), Tsai, M. (Michael), Wang, F. F. (Fei Fei), Weeks, D. E. (Daniel E.), Yanek, L. R. (Lisa R.), Wilson, J. G. (James G.), Abecasis, G. (Goncalo), Arnett, D. K. (Donna K.), Becker, L. C. (Lewis C.), Blangercy, J. (John), Boerwinkle, E. (Eric), Bowden, D. W. (Donald W.), Chang, Y.-C. (Yi-Cheng), Chen, Y. I. (Yii-Der, I), Choi, W. J. (Won Jung), Correa, A. (Adolfo), Curran, J. E. (Joanne E.), Daly, M. J. (Mark J.), DutcherE, S. K. (Susan K.), Ellinor, P. T. (Patrick T.), Fornage, M. (Myriam), Freedman, B. I. (Barry, I), Gabriel, S. (Stacey), Germer, S. (Soren), Gibbs, R. A. (Richard A.), He, J. (Jiang), Hveem, K. (Kristian), Jarvik, G. P. (Gail P.), Kaplan, R. C. (Robert C.), Kardia, S. L. (Sharon L. R.), Kennyn, E. (Eimear), Kim, R. W. (Ryan W.), Kooperberg, C. (Charles), Laurie, C. C. (Cathy C.), Lee, S. (Seonwook), Lloyd-Jones, D. M. (Don M.), Loos, R. J. (Ruth J. F.), Lubitz, S. A. (Steven A.), Mathias, R. A. (Rasika A.), Martinez, K. A. (Karine A. Viaud), McGarvey, S. T. (Stephen T.), Mitche, B. D. (Braxton D.), Nickerson, D. A. (Deborah A.), North, K. E. (Kari E.), Palotie, A. (Aarno), Park, C. J. (Cheol Joo), Psat, B. M. (Bruce M. Y.), Rao, D. C. (D. C.), Redline, S. (Susan), Reiner, A. P. (Alexander P.), Seo, D. (Daekwan), Seo, J.-S. (Jeong-Sun), Smith, A. V. (Albert, V), Tracy, R. P. (Russell P.), Kathiresan, S. (Sekar), Cupples, L. A. (L. Adrienne), Rotten, J. I. (Jerome, I), Morrison, A. C. (Alanna C.), Rich, S. S. (Stephen S.), Ripatti, S. (Samuli), Wilier, C. (Cristen), Peloso, G. M. (Gina M.), Vasan, R. S. (Ramachandran S.), Abe, N. (Namiko), Albert, C. (Christine), Almasy, L. (Laura), Alonso, A. (Alvaro), Ament, S. (Seth), Anderson, P. (Peter), Applebaum-Bowden, D. (Deborah), Arking, D. (Dan), Ashley-Koch, A. (Allison), Auer, P. (Paul), Avramopoulos, D. (Dimitrios), Barnard, J. (John), Barnes, K. (Kathleen), Barr, R. G. (R. Graham), Barron-Casella, E. (Emily), Beaty, T. (Terri), Becker, D. (Diane), Beer, R. (Rebecca), Begum, F. (Ferdouse), Beitelshees, A. (Amber), Benjamin, E. (Emelia), Bezerra, M. (Marcos), Bielak, L. (Larry), Blackwel, T. (Thomas), Bowler, R. (Russell), Broecke, U. (Ulrich), Bunting, K. (Karen), Burchard, E. (Esteban), Buth, E. (Erin), Cardwel, J. (Jonathan), Carty, C. (Cara), Casaburi, R. (Richard), Casella, J. (James), Chaffin, M. (Mark), Chang, C. (Christy), Chasman, D. (Daniel), Chavan, S. (Sameer), Chen, B.-J. (Bo-Juen), Chen, W.-M. (Wei-Min), Chol, M. (Michael), Choi, S. H. (Seung Hoan), Chuang, L.-M. (Lee-Ming), Chung, M. (Mina), Conomos, M. P. (Matthew P.), Cornell, E. (Elaine), Crapo, J. (James), Curtis, J. (Jeffrey), Custer, B. (Brian), Damcott, C. (Coleen), Darbar, D. (Dawood), Das, S. (Sayantan), David, S. (Sean), Davis, C. (Colleen), Daya, M. (Michelle), de Andrade, M. (Mariza), DeBaunuo, M. (Michael), Duan, Q. (Qing), Devine, R. D. (Ranjan Deka Dawn DeMeo Scott), Duggirala, Q. R. (Qing Ravi), Durda, J. P. (Jon Peter), Dutcher, S. (Susan), Eaton, C. (Charles), Ekunwe, L. (Lynette), Farber, C. (Charles), Farnaml, L. (Leanna), Fingerlin, T. (Tasha), Flickinger, M. (Matthew), Franceschini, N. (Nora), Fu, M. (Mao), Fullerton, S. M. (Stephanie M.), Fulton, L. (Lucinda), Gan, W. (Weiniu), Gao, Y. (Yan), Gass, M. (Margery), Ge, B. (Bruce), Geng, X. P. (Xiaoqi Priscilla), Gignoux, C. (Chris), Gladwin, M. (Mark), Glahn, D. (David), Gogarten, S. (Stephanie), Gong, D.-W. (Da-Wei), Goring, H. (Harald), Gu, C. C. (C. Charles), Guan, Y. (Yue), Guo, X. (Xiuqing), Haessler, J. (Jeff), Hall, M. (Michael), Harris, D. (Daniel), Hawle, N. Y. (Nicola Y.), Heavner, B. (Ben), Heckbert, S. (Susan), Hernandez, R. (Ryan), Herrington, D. (David), Hersh, C. (Craig), Hidalgo, B. (Bertha), Hixson, J. (James), Hokanson, J. (John), Hong, E. (Elliott), Hoth, K. (Karin), Hsiung, C. A. (Chao Agnes), Huston, H. (Haley), Hwu, C. M. (Chii Min), Jackson, R. (Rebecca), Jain, D. (Deepti), Jaquish, C. (Cashell), Jhun, M. A. (Min A.), Johnsen, J. (Jill), Johnson, A. (Andrew), Johnson, C. (Craig), Johnston, R. (Rich), Jones, K. (Kimberly), Kang, H. M. (Hyun Min), Kaufman, L. (Laura), Kell, S. Y. (Shannon Y.), Kessler, M. (Michael), Kinney, G. (Greg), Konkle, B. (Barbara), Kramer, H. (Holly), Krauter, S. (Stephanie), Lange, C. (Christoph), Lange, E. (Ethan), Laurie, C. (Cecelia), LeBoff, M. (Meryl), Lee, S. S. (Seunggeun Shawn), Lee, W.-J. (Wen-Jane), LeFaive, J. (Jonathon), Levine, D. (David), Levy, D. (Dan), Lewis, J. (Joshua), Li, Y. (Yun), Lin, H. (Honghuang), Lin, K. H. (Keng Han), Lin, X. (Xihong), Liu, S. (Simin), Liu, Y. (Yongmei), Lunetta, K. (Kathryn), Luo, J. (James), Mahaney, M. (Michael), Make, B. (Barry), Manichaikul, A. (Ani), Mansonl, J. (JoAnn), Margolin, L. (Lauren), Mathai, S. (Susan), McArdle, P. (Patrick), Mcdonald, M.-L. (Merry-Lynn), McFarland, S. (Sean), McHugh, C. (Caitlin), Mei, H. (Hao), Meyers, D. A. (Deborah A.), Mikulla, J. (Julie), Min, N. (Nancy), Minear, M. (Mollie), Minster, R. L. (Ryan L.), Musani, S. (Solomon), Mwasongwe, S. (Stanford), Mychaleckyj, J. C. (Josyf C.), Nadkarni, G. (Girish), Naik, R. (Rakhi), Naseri, T. (Take), Nekhai, S. (Sergei), Nelson, S. C. (Sarah C.), Nickerson, D. (Deborah), Connell, J. O. (Jeff O.), Connor, T. O. (Tim O.), Ochs-Balcom, H. (Heather), Pankow, J. (James), Papanicolaou, G. (George), Parkerl, M. (Margaret), Parsa, A. (Afshin), Penchey, S. (Sara), Perez, M. (Marco), Peters, U. (Ulrike), Phillips, L. S. (Lawrence S.), Phillips, S. (Sam), Pollin, T. (Toni), Post, W. (Wendy), Becker, J. P. (Julia Powers), Boorgula, M. P. (Meher Preethi), Preuss, M. (Michael), Prokopenko, D. (Dmitry), Qasba, P. (Pankaj), Qiao, D. (Dandi), Rafaels, N. (Nicholas), Raffield, L. (Laura), Rasmussen-Torvik, L. (Laura), Ratan, A. (Aakrosh), Reed, R. (Robert), Reganl, E. (Elizabeth), Reupena, M. S. (Muagututi Sefuiva), Rice, K. (Ken), Roden, D. (Dan), Roselli, C. (Carolina), Ruczinski, I. (Ingo), Russel, P. (Pamela), Ruuska, S. (Sarah), Ryan, K. (Kathleen), Sabino, E. C. (Ester Cerdeira), Sakornsakolpatl, P. (Phuwanat), Salzberg, S. (Steven), Sandow, K. (Kevin), Sankaran, V. G. (Vijay G.), Scheller, C. (Christopher), Schmidt, E. (Ellen), Schwander, K. (Karen), Schwartz, D. (David), Sciurba, F. (Frank), Seidman, C. (Christine), Seidman, J. (Jonathan), Sheehan, V. (Vivien), Shetty, A. (Amol), Shetty, A. (Aniket), Sheu, W. H. (Wayne Hui-Heng), Shoemaker, M. B. (M. Benjamin), Silver, B. (Brian), Silvermanl, E. (Edwin), Smith, J. (Jennifer), Smith, J. (Josh), Smith, N. (Nicholas), Smith, T. (Tanja), Smoller, S. (Sylvia), Snively, B. (Beverly), Soferlm, T. (Tamar), Streeten, E. (Elizabeth), Su, J. L. (Jessica Lasky), Sung, Y. J. (Yun Ju), Sylvia, J. (Jody), Sztalryd, C. (Carole), Taliun, D. (Daniel), Tang, H. (Hua), Taub, M. (Margaret), Taylor, K. D. (Kent D.), Taylor, S. (Simeon), Telen, M. (Marilyn), Thornton, T. A. (Timothy A.), Tinker, L. (Lesley), Tirschwel, D. (David), Tiwari, H. (Hemant), Vaidya, D. (Dhananjay), VandeHaar, P. (Peter), Vrieze, S. (Scott), Walker, T. (Tarik), Wallace, R. (Robert), Waits, A. (Avram), Wan, E. (Emily), Wang, H. (Heming), Watson, K. (Karol), Weir, B. (Bruce), Weiss, S. (Scott), Weng, L.-C. (Lu-Chen), Williams, K. (Kayleen), Williams, L. K. (L. Keoki), Wilson, C. (Carla), Wong, Q. (Quenna), Xu, H. (Huichun), Yang, I. (Ivana), Yang, R. (Rongze), Zaghlou, N. (Norann), Zekavat, M. (Maryam), Zhang, Y. (Yingze), Zhao, S. X. (Snow Xueyan), Zhao, W. (Wei), Zni, D. (Degui), Zhou, X. (Xiang), Zhu, X. (Xiaofeng), Zody, M. (Michael), Zoellner, S. (Sebastian), Daly, M. (Mark), Jacob, H. (Howard), Matakidou, A. (Athena), Runz, H. (Heiko), John, S. (Sally), Plenge, R. (Robert), McCarthy, M. (Mark), Hunkapiller, J. (Julie), Ehm, M. (Meg), Waterworth, D. (Dawn), Fox, C. (Caroline), Malarstig, A. (Anders), Klinger, K. (Kathy), Call, K. (Kathy), Mkel, T. (Tomi), Kaprio, J. (Jaakko), Virolainen, P. (Petri), Pulkki, K. (Kari), Kilpi, T. (Terhi), Perola, M. (Markus), Partanen, J. (Jukka), Pitkranta, A. (Anne), Kaarteenaho, R. (Riitta), Vainio, S. (Seppo), Savinainen, K. (Kimmo), Kosma, V.-M. (Veli-Matti), Kujala, U. (Urho), Tuovila, O. (Outi), Hendolin, M. (Minna), Pakkanen, R. (Raimo), Waring, J. (Jeff), Riley-Gillis, B. (Bridget), Liu, J. (Jimmy), Biswas, S. (Shameek), Diogo, D. (Dorothee), Marshall, C. (Catherine), Hu, X. (Xinli), Gossel, M. (Matthias), Schleutker, J. (Johanna), Arvas, M. (Mikko), Hinttala, R. (Reetta), Kettunen, J. (Johannes), Laaksonen, R. (Reijo), Mannermaa, A. (Arto), Paloneva, J. (Juha), Soininen, H. (Hilkka), Julkunen, V. (Valtteri), Remes, A. (Anne), Klviinen, R. (Reetta), Hiltunen, M. (Mikko), Peltola, J. (Jukka), Tienari, P. (Pentti), Rinne, J. (Juha), Ziemann, A. (Adam), Waring, J. (Jeffrey), Esmaeeli, S. (Sahar), Smaoui, N. (Nizar), Lehtonen, A. (Anne), Eaton, S. (Susan), Landenper, S. (Sanni), Michon, J. (John), Kerchner, G. (Geoff), Bowers, N. (Natalie), Teng, E. (Edmond), Eicher, J. (John), Mehta, V. (Vinay), Gormle, P. Y. (Padhraig Y.), Linden, K. (Kari), Whelan, C. (Christopher), Xu, F. (Fanli), Pulford, D. (David), Frkkil, M. (Martti), Pikkarainen, S. (Sampsa), Jussila, A. (Airi), Blomster, T. (Timo), Kiviniemi, M. (Mikko), Voutilainen, M. (Markku), Georgantas, B. (Bob), Heap, G. (Graham), Rahimov, F. (Fedik), Usiskin, K. (Keith), Maranville, J. (Joseph), Lu, T. (Tim), Oh, D. (Danny), Kalpala, K. (Kirsi), Miller, M. (Melissa), McCarthy, L. (Linda), Eklund, K. (Kari), Palomki, A. (Antti), Isomki, P. (Pia), Piri, L. (Laura), Kaipiainen-Seppnen, O. (Oili), Lertratanaku, A. (Apinya), Bing, D. C. (David Close Marla Hochfeld Nan), Gordillo, J. E. (Jorge Esparza), Mars, N. (Nina), Laitinen, T. (Tarja), Pelkonen, M. (Margit), Kauppi, P. (Paula), Kankaanranta, H. (Hannu), Harju, T. (Terttu), Greenberg, S. (Steven), Chen, H. (Hubert), Betts, J. (Jo), Ghosh, S. (Soumitra), Salomaa, V. (Veikko), Niiranen, T. (Teemu), Juonala, M. (Markus), Metsrinne, K. (Kaj), Khnen, M. (Mika), Junttila, J. (Juhani), Laakso, M. (Markku), Pihlajamki, J. (Jussi), Sinisalo, J. (Juha), Taskinen, M.-R. (Marja-Riitta), Tuomi, T. (Tiinamaija), Laukkanen, J. (Jari), Challis, B. (Ben), Peterson, A. (Andrew), Chu, A. (Audrey), Parkkinen, J. (Jaakko), Muslin, A. (Anthony), Joensuu, H. (Heikki), Meretoja, T. (Tuomo), Aaltonen, L. (Lauri), Auranen, A. (Annika), Karihtala, P. (Peeter), Kauppila, S. (Saila), Auvinen, P. (Pivi), Elenius, K. (Klaus), Popovic, R. (Relja), Schutzman, J. (Jennifer), Loboda, A. (Andrey), Chhibber, A. (Aparna), Lehtonen, H. (Heli), McDonough, S. (Stefan), Crohns, M. (Marika), Kulkarni, D. (Diptee), Kaarniranta, K. (Kai), Turunen, J. (Joni), Ollila, T. (Terhi), Seitsonen, S. (Sanna), Uusitalo, H. (Hannu), Aaltonen, V. (Vesa), Uusitalo-Jrvinen, H. (Hannele), Luodonp, M. (Marja), Hautala, N. (Nina), Strauss, E. (Erich), Chen, H. (Hao), Podgornaia, A. (Anna), Hoffman, J. (Joshua), Tasanen, K. (Kaisa), Huilaja, L. (Laura), Hannula-Jouppi, K. (Katariina), Salmi, T. (Teea), Peltonen, S. (Sirkku), Koulu, L. (Leena), Harvima, I. (Ilkka), Wu, Y. (Ying), Choy, D. (David), Jalanko, A. (Anu), Kajanne, R. (Risto), Lyhs, U. (Ulrike), Kaunisto, M. (Mari), Davis, J. W. (Justin Wade), Quarless, D. (Danjuma), Petrovski, S. (Slav), Chen, C.-Y. (Chia-Yen), Bronson, P. (Paola), Yang, R. (Robert), Chang, D. (Diana), Bhangale, T. (Tushar), Holzinger, E. (Emily), Wang, X. (Xulong), Chen, X. (Xing), Auro, K. (Kirsi), Wang, C. (Clarence), Xu, E. (Ethan), Auge, F. (Franck), Chatelain, C. (Clement), Kurki, M. (Mitja), Karjalainen, J. (Juha), Havulinna, A. (Aki), Palin, K. (Kimmo), Palta, P. (Priit), Parolo, P. D. (Pietro Della Briotta), Zhou, W. (Wei), Lemmel, S. (Susanna), Rivas, M. (Manuel), Harju, J. (Jarmo), Lehisto, A. (Arto), Ganna, A. (Andrea), Llorens, V. (Vincent), Karlsson, A. (Antti), Kristiansson, K. (Kati), Hyvrinen, K. (Kati), Ritari, J. (Jarmo), Wahlfors, T. (Tiina), Koskinen, M. (Miika), Pylkäs, K. (Katri), Kalaoja, M. (Marita), Karjalainen, M. (Minna), Mantere, T. (Tuomo), Kangasniemi, E. (Eeva), Heikkinen, S. (Sami), Laakkonen, E. (Eija), Kononen, J. (Juha), Loukola, A. (Anu), Laiho, P. (Pivi), Sistonen, T. (Tuuli), Kaiharju, E. (Essi), Laukkanen, M. (Markku), Jrvensivu, E. (Elina), Lhteenmki, S. (Sini), Mnnikk, L. (Lotta), Wong, R. (Regis), Mattsson, H. (Hannele), Hiekkalinna, T. (Tero), Jimnez, M. G. (Manuel Gonzlez), Donner, K. (Kati), Prn, K. (KaIle), Nunez-Fontarnau, J. (Javier), Kilpelinen, E. (Elina), Sipi, T. P. (Timo P.), Brein, G. (Georg), Dada, A. (Alexander), Awaisa, G. (Ghazal), Shcherban, A. (Anastasia), Sipil, T. (Tuomas), Laivuori, H. (Hannele), Kiiskinen, T. (Tuomo), Siirtola, H. (Harri), Tabuenca, J. G. (Javier Gracia), Kallio, L. (Lila), Soini, S. (Sirpa), Pitknen, K. (Kimmo), and Kuopio, T. (Teijo)

Subjects
Cardiovascular genetics, Genome-wide association studies
Abstract

Autosomal genetic analyses of blood lipids have yielded key insights for coronary heart disease (CHD). However, X chromosome genetic variation is understudied for blood lipids in large sample sizes. We now analyze genetic and blood lipid data in a high-coverage whole X chromosome sequencing study of 65,322 multi-ancestry participants and perform replication among 456,893 European participants. Common alleles on chromosome Xq23 are strongly associated with reduced total cholesterol, LDL cholesterol, and triglycerides (min P = 8.5 × 10−72), with similar effects for males and females. Chromosome Xq23 lipid-lowering alleles are associated with reduced odds for CHD among 42,545 cases and 591,247 controls (P = 1.7 × 10−4), and reduced odds for diabetes mellitus type 2 among 54,095 cases and 573,885 controls (P = 1.4 × 10−5). Although we observe an association with increased BMI, waist-to-hip ratio adjusted for BMI is reduced, bioimpedance analyses indicate increased gluteofemoral fat, and abdominal MRI analyses indicate reduced visceral adiposity. Co-localization analyses strongly correlate increased CHRDL1 gene expression, particularly in adipose tissue, with reduced concentrations of blood lipids.

Published
2021

12. Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry

Author

de las Fuentes, L., primary, Sung, Y. J., additional, Sitlani, C. M., additional, Avery, C. L., additional, Bartz, T. M., additional, Keyser, C. de, additional, Evans, D. S., additional, Li, X., additional, Musani, S. K., additional, Ruiter, R., additional, Smith, A. V., additional, Sun, F., additional, Trompet, S., additional, Xu, H., additional, Arnett, D. K., additional, Bis, J. C., additional, Broeckel, U., additional, Busch, E. L., additional, Chen, Y.-D. I., additional, Correa, A., additional, Cummings, S. R., additional, Floyd, J. S., additional, Ford, I., additional, Guo, X., additional, Harris, T. B., additional, Ikram, M. A., additional, Lange, L., additional, Launer, L. J., additional, Reiner, A. P., additional, Schwander, K., additional, Smith, N. L., additional, Sotoodehnia, N., additional, Stewart, J. D., additional, Stott, D. J., additional, Stürmer, T., additional, Taylor, K. D., additional, Uitterlinden, A., additional, Vasan, R. S., additional, Wiggins, K. L., additional, Cupples, L. A., additional, Gudnason, V., additional, Heckbert, S. R., additional, Jukema, J. W., additional, Liu, Y., additional, Psaty, B. M., additional, Rao, D. C., additional, Rotter, J. I., additional, Stricker, B., additional, Wilson, J. G., additional, and Whitsel, E. A., additional

Published
2019
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14. Evidence for genetic linkage of autism to chromosomes 7 and 4

Author

Schellenberg, G D, Dawson, G, Sung, Y J, Estes, A, Munson, J, Rosenthal, E, Rothstein, J, Flodman, P, Smith, M, Coon, H, Leong, L, Yu, C-E, Stodgell, C, Rodier, P M, Spence, M A, Minshew, N, McMahon, W M, and Wijsman, E M

Published
2006

16. Comparison of output power of InGaN laser diodes for different Al compositions in the AlGaN n-cladding layer.

Author

Ryu, H. Y., Ha, K. H., Son, J. K., Paek, H. S., Sung, Y. J., Kim, K. S., Kim, H. K., Park, Y., Lee, S. N., and Nam, O. H.

Subjects
SEMICONDUCTOR lasers, REFRACTIVE index, GALLIUM, NITRIDES, INDIUM, ALUMINUM, QUANTUM wells
Abstract

The output power of InGaN multiple-quantum-well laser diodes (LDs) emitting at 405 nm wavelength is compared for several Al composition in the AlGaN n-cladding layer. The Al composition has been varied from 2% to 6% to study the effect of n-cladding refractive index on threshold current and slope efficiency of the LDs. As the Al composition in the AlGaN n-cladding layer increases, both threshold current and slope efficiency decrease. This behavior can be explained by the change in optical field distribution with refractive index of the AlGaN n-cladding layer. It is found that the Al composition of ¿4% would be advantageous for achieving more than 100 mW output power and high level of catastrophic optical damage. [ABSTRACT FROM AUTHOR]

Published
2009
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17. A study of transparent contact to vertical GaN-based light-emitting diodes.

Author

Kim, D. W., Lee, H. Y., Yeom, G. Y., and Sung, Y. J.

Subjects
LIGHT emitting diodes, SEMICONDUCTOR diodes, ELECTROLUMINESCENT devices, LIGHT sources, OPTICAL communications, SEMICONDUCTORS, PHYSICS
Abstract

In this study, transparent indium tin oxide (ITO) deposited by sputtering was applied to laser lift-off (LLO) GaN-based vertical light-emitting diodes (VLEDs) and the electrical and optical properties of ITO films were measured as a function of annealing conditions. The measured minimum resistivity of ITO film was about 3.78×10-4 Ω cm and the measured optical transmittance at 460 nm was 96.8% after the annealing process. In this condition, about 1×10-5 Ω cm2 of ITO contact resistance to LLO n-GaN could be obtained. By applying the transparent ITO layer to the LLO GaN-based VLEDs, a significant decrease of the forward operating voltage from 3.3 to 3.8 V at 20 mA could be obtained. [ABSTRACT FROM AUTHOR]

Published
2005
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18. The Patient State Index is well balanced for propofol sedation

Author

Lee, K H, Kim, Y H, Sung, Y J, and Oh, M K

Subjects
Original Article
Abstract

The SEDLine™ monitor derived patient state index (PSI) is used to follow the depth of sedation. The demand for propofol sedation by anesthesiologists or non-anesthesiologists is increasing, and there are only a few studies addressing the relationship between PSI and propofol sedation. We aimed to investigate the ability of PSI index to identify the correct level of sedation of our patients during induction to anesthesia with target-controlled infusions of propofol.Twenty patients were enrolled in this study. The target effect site concentration of propofol was set at 1.5 μg/ml followed by increments of 0.5 μg/ml every five minutes. The PSI values and Modified Observer's Assessment of Alertness/Sedation (MOAA/S) scale were recorded every twenty-five seconds during the infusion of propofol. Patients were considered losing verbal responsiveness at MOAA/S scale ≤ 2. Also, blood pressure, heart rate, and oxygen saturation were recorded every five minutes.The PSI values corresponding to the sedation of various depths (MOAA/S scales) and alertness with verbal response were significantly different (p0.001). We observed a good correlation of the PSI values to the decreasing MOAA/S scale (r =0.87667).The PSI index is well correlated with MOAA/S scale and effectively distinguishes the level of sedation during propofol infusion. Hippokratia 2015; 19 (3): 235-238.

Published
2015

20. Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat

Author

Sung, Y J, primary, Pérusse, L, additional, Sarzynski, M A, additional, Fornage, M, additional, Sidney, S, additional, Sternfeld, B, additional, Rice, T, additional, Terry, J G, additional, Jacobs, D R, additional, Katzmarzyk, P, additional, Curran, J E, additional, Jeffrey Carr, J, additional, Blangero, J, additional, Ghosh, S, additional, Després, J-P, additional, Rankinen, T, additional, Rao, D C, additional, and Bouchard, C, additional

Published
2015
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21. Genome-wide meta-analyses of smoking behaviors in African Americans

Author

Chen, G K, Bandera, E V, Chanock, S J, Blot, W J, Wessel, J, Deming, S L, Eaton, C B, Hamidovic, A, Buxbaum, S G, Nalls, M A, Bernstein, L, Diver, W R, Kasberger, J L, Ambrosone, C B, Thacker, E L, Becker, L, Broeckel, U, Tranah, G J, Sung, Y J, Bergen, A W, Brown, W M, Caporaso, N, Kim, Y, Evans, M K, Arnett, D, Berndt, S I, Fornage, M, Petruzella, S, Becker, D M, Casey, G, David, S P, and Evans, D S

Abstract

The identification and exploration of genetic loci that influence smoking behaviors have been conducted primarily in populations of the European ancestry. Here we report results of the first genome-wide association study meta-analysis of smoking behavior in African Americans in the Study of Tobacco in Minority Populations Genetics Consortium (n=32 389). We identified one non-coding single-nucleotide polymorphism (SNP; rs2036527[A]) on chromosome 15q25.1 associated with smoking quantity (cigarettes per day), which exceeded genome-wide significance (β=0.040, s.e.=0.007, P=1.84 × 10−8). This variant is present in the 5′-distal enhancer region of the CHRNA5 gene and defines the primary index signal reported in studies of the European ancestry. No other SNP reached genome-wide significance for smoking initiation (SI, ever vs never smoking), age of SI, or smoking cessation (SC, former vs current smoking). Informative associations that approached genome-wide significance included three modestly correlated variants, at 15q25.1 within PSMA4, CHRNA5 and CHRNA3 for smoking quantity, which are associated with a second signal previously reported in studies in European ancestry populations, and a signal represented by three SNPs in the SPOCK2 gene on chr10q22.1. The association at 15q25.1 confirms this region as an important susceptibility locus for smoking quantity in men and women of African ancestry. Larger studies will be needed to validate the suggestive loci that did not reach genome-wide significance and further elucidate the contribution of genetic variation to disparities in cigarette consumption, SC and smoking-attributable disease between African Americans and European Americans.

Published
2012
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29. Endometriosis, endometrium, implantation and fallopian tube

Author

Tan, C. W., primary, Lee, Y. H., additional, Choolani, M., additional, Tan, H. H., additional, Griffith, L., additional, Chan, J., additional, Chuang, P. C., additional, Wu, M. H., additional, Lin, Y. J., additional, Tsai, S. J., additional, Rahmati, M., additional, Petitbarat, M., additional, Dubanchet, S., additional, Bensussan, A., additional, Chaouat, G., additional, Ledee, N., additional, Bissonnette, L., additional, Haouzi, D., additional, Monzo, C., additional, Traver, S., additional, Bringer, S., additional, Faidherbe, J., additional, Perrochia, H., additional, Ait-Ahmed, O., additional, Dechaud, H., additional, Hamamah, S., additional, Ibrahim, M. G., additional, de Arellano, M. L. B., additional, Sachtleben, M., additional, Chiantera, V., additional, Frangini, S., additional, Younes, S., additional, Schneider, A., additional, Plendl, J., additional, Mechsner, S., additional, Ono, M., additional, Hamai, H., additional, Chikawa, A., additional, Teramura, S., additional, Takata, R., additional, Sugimoto, T., additional, Iwahashi, K., additional, Ohhama, N., additional, Nakahira, R., additional, Shigeta, M., additional, Park, I. H., additional, Lee, K. H., additional, Sun, H. G., additional, Kim, S. G., additional, Lee, J. H., additional, Kim, Y. Y., additional, Kim, H. J., additional, Jeon, G. H., additional, Kim, C. M., additional, Bocca, S., additional, Wang, H., additional, Anderson, S., additional, Yu, L., additional, Horcajadas, J., additional, Oehninger, S., additional, Bastu, E., additional, Mutlu, M. F., additional, Celik, C., additional, Yasa, C., additional, Dural, O., additional, Buyru, F., additional, Quintana, F., additional, Cobo, A., additional, Remohi, J., additional, Ferrando, M., additional, Matorras, R., additional, Bermejo, A., additional, Iglesias, C., additional, Cerrillo, M., additional, Ruiz, M., additional, Blesa, D., additional, Simon, C., additional, Garcia-Velasco, J. A., additional, Chamie, L., additional, Ribeiro, D. M. F., additional, Riboldi, M., additional, Pereira, R., additional, Rosa, M. B., additional, Gomes, C., additional, de Mello, P. H., additional, Fettback, P., additional, Domingues, T., additional, Cambiaghi, A., additional, Soares, A. C. P., additional, Kimati, C., additional, Motta, E. L. A., additional, Serafini, P., additional, Hapangama, D. K., additional, Valentijn, A. J., additional, Al-Lamee, H., additional, Palial, K., additional, Drury, J. A., additional, von Zglinicki, T., additional, Saretzki, G., additional, Gargett, C. E., additional, Liao, C. Y., additional, Sung, Y. J., additional, Li, H. Y., additional, Morotti, M., additional, Remorgida, V., additional, Venturini, P. L., additional, Ferrero, S., additional, Nabeta, M., additional, Iki, A., additional, Hashimoto, H., additional, Koizumi, M., additional, Matsubara, Y., additional, Hamada, K., additional, Fujioka, T., additional, Matsubara, K., additional, Kusanagi, Y., additional, Nawa, A., additional, Zanatta, A., additional, da Rocha, A. M., additional, Guerra, J. L., additional, Cogliati, B., additional, Bianchi, P. d. M., additional, Prieto, B., additional, Exposito, A., additional, Mendoza, R., additional, Rabanal, A., additional, Bedaiwy, M., additional, Yi, L., additional, Dahoud, W., additional, Liu, J., additional, Hurd, W., additional, Falcone, T., additional, Biscotti, C., additional, Mesiano, S., additional, Sugiyama, R., additional, Nakagawa, K., additional, Nishi, Y., additional, Kuribayashi, Y., additional, Akira, S., additional, Germeyer, A., additional, Rosner, S., additional, Jauckus, J., additional, Strowitzki, T., additional, von Wolff, M., additional, Khan, K. N., additional, Kitajima, M., additional, Fujishita, A., additional, Nakashima, M., additional, Masuzaki, H., additional, Kajihara, T., additional, Ishihara, O., additional, Brosens, J., additional, Vezmar, K., additional, Savournin, V., additional, Balet, R., additional, Loh, S. F., additional, Tannenbaum, S. R., additional, Chan, J. K. Y., additional, Scarella, A., additional, Chamy, V., additional, Devoto, L., additional, Abrao, M., additional, Sovino, H., additional, Krasnopolskaya, K., additional, Popov, A., additional, Kabanova, D., additional, Beketova, A., additional, Ivakhnenko, V., additional, Shohayeb, A., additional, Wahba, A., additional, Abousetta, A., additional, al-inany, H., additional, El Daly, A., additional, Zayed, M., additional, Kvaskoff, M., additional, Han, J., additional, Missmer, S. A., additional, Navarro, P., additional, Meola, J., additional, Ribas, C. P., additional, Paz, C. P., additional, Ferriani, R. A., additional, Donabela, F. C., additional, Tafi, E., additional, Maggiore, U. L. R., additional, Scala, C., additional, Hackl, J., additional, Strehl, J., additional, Wachter, D., additional, Dittrich, R., additional, Cupisti, S., additional, Hildebrandt, T., additional, Lotz, L., additional, Attig, M., additional, Hoffmann, I., additional, Renner, S., additional, Hartmann, A., additional, Beckmann, M. W., additional, Urquiza, F., additional, Ferrer, C., additional, Incera, E., additional, Azpiroz, A., additional, Junovich, G., additional, Pappalardo, C., additional, Guerrero, G., additional, Pasqualini, S., additional, Gutierrez, G., additional, Corti, L., additional, Sanchez, A. M., additional, Bordignon, P. P., additional, Santambrogio, P., additional, Levi, S., additional, Persico, P., additional, Vigano, P., additional, Papaleo, E., additional, Ferrari, S., additional, Candiani, M., additional, van der Houwen, L. E. E., additional, Schreurs, A. M. F., additional, Lambalk, C. B., additional, Schats, R., additional, Hompes, P. G. A., additional, Mijatovic, V., additional, Xu, S. Y., additional, Li, J., additional, Chen, X. Y., additional, Chen, S. Q., additional, Guo, L. Y., additional, Mathew, D., additional, Nunes, Q., additional, Lane, B., additional, Fernig, D., additional, Hapangama, D., additional, Lind, T., additional, Hammarstrom, M., additional, Golmann, D., additional, Rodriguez-Wallberg, K., additional, Hestiantoro, A., additional, Cakra, A., additional, Aulia, A., additional, Al-Inany, H., additional, Houston, B., additional, Farquhar, C., additional, Tagliaferri, V., additional, Gagliano, D., additional, Immediata, V., additional, Tartaglia, C., additional, Zumpano, A., additional, Campagna, G., additional, Lanzone, A., additional, Guido, M., additional, Matsuzaki, S., additional, Darcha, C., additional, Botchorishvili, R., additional, Pouly, J. L., additional, Mage, G., additional, Canis, M., additional, Shivhare, S. B., additional, Bulmer, J. N., additional, Innes, B. A., additional, Lash, G. E., additional, de Graaff, A. A., additional, Zandstra, H., additional, Smits, L. J., additional, Van Beek, J. J., additional, Dunselman, G. A. J., additional, Bozdag, G., additional, Calis, P. T., additional, Demiralp, D. O., additional, Ayhan, B., additional, Igci, N., additional, Yarali, H., additional, Acar, N., additional, Er, H., additional, Ozmen, A., additional, Ustunel, I., additional, Korgun, E. T., additional, Kuroda, K., additional, Kuroda, M., additional, Arakawa, A., additional, Kitade, M., additional, Brosens, A. I., additional, Brosens, J. J., additional, Takeda, S., additional, and Yao, T., additional

Published
2013
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30. Genome-wide meta-analyses of smoking behaviors in African Americans

Author

David, S P, primary, Hamidovic, A, additional, Chen, G K, additional, Bergen, A W, additional, Wessel, J, additional, Kasberger, J L, additional, Brown, W M, additional, Petruzella, S, additional, Thacker, E L, additional, Kim, Y, additional, Nalls, M A, additional, Tranah, G J, additional, Sung, Y J, additional, Ambrosone, C B, additional, Arnett, D, additional, Bandera, E V, additional, Becker, D M, additional, Becker, L, additional, Berndt, S I, additional, Bernstein, L, additional, Blot, W J, additional, Broeckel, U, additional, Buxbaum, S G, additional, Caporaso, N, additional, Casey, G, additional, Chanock, S J, additional, Deming, S L, additional, Diver, W R, additional, Eaton, C B, additional, Evans, D S, additional, Evans, M K, additional, Fornage, M, additional, Franceschini, N, additional, Harris, T B, additional, Henderson, B E, additional, Hernandez, D G, additional, Hitsman, B, additional, Hu, J J, additional, Hunt, S C, additional, Ingles, S A, additional, John, E M, additional, Kittles, R, additional, Kolb, S, additional, Kolonel, L N, additional, Le Marchand, L, additional, Liu, Y, additional, Lohman, K K, additional, McKnight, B, additional, Millikan, R C, additional, Murphy, A, additional, Neslund-Dudas, C, additional, Nyante, S, additional, Press, M, additional, Psaty, B M, additional, Rao, D C, additional, Redline, S, additional, Rodriguez-Gil, J L, additional, Rybicki, B A, additional, Signorello, L B, additional, Singleton, A B, additional, Smoller, J, additional, Snively, B, additional, Spring, B, additional, Stanford, J L, additional, Strom, S S, additional, Swan, G E, additional, Taylor, K D, additional, Thun, M J, additional, Wilson, A F, additional, Witte, J S, additional, Yamamura, Y, additional, Yanek, L R, additional, Yu, K, additional, Zheng, W, additional, Ziegler, R G, additional, Zonderman, A B, additional, Jorgenson, E, additional, Haiman, C A, additional, and Furberg, H, additional

Published
2012
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44. Development of AlInGaN-based Blue laser diodes

Author

Park, Y., primary, Son, J. K., additional, Nam, O. H., additional, Lee, S. N., additional, Kim, K. S., additional, Paek, H. S., additional, Sung, Y. J., additional, Kim, H. K., additional, and Jang, T., additional

Published
2007
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50. Recent progress of high-power InGaN blue-violet laser diodes

Author

Ryu, H. Y., primary, Ha, K. H., additional, Lee, S. N., additional, Choi, K. K., additional, Jang, T., additional, Son, J. K., additional, Kim, H. G., additional, Chae, J. H., additional, Paek, H. S., additional, Sung, Y. J., additional, Sakong, T., additional, Kim, K. S., additional, Nam, O. H., additional, and Park, Y. J., additional

Published
2006
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