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Aluminum and its alloys are essential in construction due to their lightweight nature and recyclability. To enhance durability, protection against corrosion is vital, with cataphoretic painting being particularly effective. This study evaluated the damage rate of cataphoresis coatings on AW 1050 H24 aluminum, focusing on the impact of different degreasing solutions. By analyzing temperature, concentration, and deposition time, the study found that concentrations above 5.25 % degrade surface quality due to aluminum dissolution, while temperatures between 37 °C and 50 °C are optimal. At higher temperatures, shorter deposition times improve quality, whereas longer times lead to defects. [ABSTRACT FROM AUTHOR]

3,4-methylenedioxymetamphetamine (MDMA), also known as “ecstasy”, “tulips”, or “Molly”, is an increasingly used “recreational drug” particularly among teenagers and young adults along with the widespread conviction that MDMA is a “safe drug”. The reason for this substance being abused is a desire for closeness to other people, develop a greater tolerance of their views and feelings, and even to touch them physically. According to these effects MDMA is classified also as an “empatogenic” or “entactogenic”. Although MDMA is used for the above-mentioned socially acceptable purposes, in many individuals the drug usage is followed with side-effects varying from mild to severe, potentially even life-threatening. One of the most significant complication of MDMA intoxication is hyper-thermia in the consumer. Authors presented a case of MDMA toxicity with severe hyperthermia (42 ºC) with a fatal outcome to the ecstasy-influenced subject. The aim of this article is to describe the effects of ecstasy, the “recreational drug” widely used in local pubs, dance clubs, and during open air festivals, even in the Slovak Republic.

Traffic medicine is an important part within the scope of concerns of forensic medicine. We are dealing with consequences of traffic accidents – fatal or survived – but this problem overlaps the borders of our specialization. Sustained injuries are the focus of various fields of medicine and in combination with alcohol and illicit drugs abuse this issue is growing. The following review has an ambition to bring more light into the problem concerning the effect of alcohol and cannabis (which is the most common illicit drug used worldwide) on driving abilities.

The magnetic domain structure (MDS) at the martensite transformation interface is relevant for the complete understanding of functionalities in magnetic shape memory alloys. We study the MDS in Ni50Mn25Ga20Fe5 single crystalline foil using Lorentz transmission electron microscopy. The transformation interface is stabilized by decreasing foil thickness at a thickness of about 40 nm. The martensite in the thicker region contains no twin domains and exhibits dense labyrinth MDS with magnetization out-of-plane. The austenite in the thinner region exhibits broad magnetic domains with magnetization in-plane. The transformation interface is about 1 μm broad, formed by an unusual nanosized laminated structure of austenite and martensite. Within the interface region, the two distinct MDSs interpenetrate each other, with a labyrinth MDS of martensite changing suddenly to broad magnetic domains of austenite. The changes from dense to broad domains do not follow the underlying phase changes exactly but occur on antiphase boundaries, revealing their role in the overall MDS formation. [ABSTRACT FROM AUTHOR]

Enhanced magnetic hysteresis due to boron doping in combination with magnetic shape memory effect in Ni-Mn-Ga single crystal results in new interesting functionality of magnetic shape memory (MSM) alloys such as mechanical demagnetization. In Ni50.0Mn28.5Ga21.5 single crystal, the boron doping increased magnetic coercivity from few Oe to 270 Oe while not affecting the transformation behavior and 10M martensite structure. However, the magnetic field needed for MSM effect also increased in doped sample. The magnetic behavior is compared to undoped single crystal of similar composition. The evidence from the X-ray diffraction, magnetic domain structure, magnetization loops, and temperature evolution of the magnetic coercivity points out that the enhanced hysteresis is caused by stress-induced anisotropy. [ABSTRACT FROM AUTHOR]

Optical and magneto-optical properties of single crystal of Ni50.1Mn28.4Ga21.5 magnetic shape memory alloy during its transformation from martensite to austenite phase were systematically studied. Crystal orientation was approximately along {100} planes of parent cubic austenite. X-ray reciprocal mapping confirmed modulated 10M martensite phase. Temperature depended measurements of saturation magnetization revealed the martensitic transformation at 335K during heating. Magneto-optical spectroscopy and spectroscopic ellipsometry were measured in the sample temperature range from 297 to 373K and photon energy range from 1.2 to 6.5 eV. Magneto-optical spectra of polar Kerr rotation as well as the spectra of ellipsometric parameter ψ exhibited significant changes when crossing the transformation temperature. These changes were assigned to different optical properties of Ni-Mn-Ga in martensite and austenite phases due to modification of electronic structure near the Fermi energy during martensitic transformation. [ABSTRACT FROM AUTHOR]

Intermartensite transformations (IMTs) and temperature dependence of very low twinning stress associated with Type II twin boundaries were studied experimentally in four magnetic shape memory alloys with composition Ni50Mn25 + xGa25 - x (at. %), where x was between 3.2 and 3.9. The slightly different x or Mn content resulted in slightly different martensite transformation temperatures between 309 and 328 K, but in significantly different intermartensite transformation temperatures between 10 K and 251 K, with the transformation temperature being approximately proportional to x. In all four alloys, the initial twinning stress, about 0.1 MPa at room temperature, increases sharply when approaching the IMT at lower temperatures, up to 1 MPa and more. The effect is explained by the instability of 10M martensite near the IMT from which it follows that the twinning stress dependence shall be flat for x≤2.7. That is experimentally confirmed by an additional measurement on Ni50Mn27.7Ga22.3 alloy (x = 2.7), which exhibits just slowly increasing twinning stress with decreasing temperature, with the maximum of only 0.2 MPa at 1.7 K. [ABSTRACT FROM AUTHOR]

Sinonasal cancers represent a highly heterogeneous group of head and neck cancers, for which etiological and prognostic significance of high-risk human papillomavirus (HPV) infections has not yet been conclusively established. We investigated the presence of transcriptionally-active high-risk HPV in a series of 34 sinonasal squamous cell cancer (SNSCC) cases and evaluated the effect of transcriptionally-active HPV on the overall survival. In addition, we performed a meta-analysis of previously published studies, including this study, to summarize the prevalence of HPV positivity across histological subtypes of SNSCC. The presence of transcriptionally-active HPV was detected by HPV mRNA using the polymerase chain reaction (PCR) or in situ hybridization (ISH). p16 expression was evaluated as a surrogate marker for transcriptionallyactive HPV infection by immunohistochemistry (IHC), the presence of high-risk HPV DNA was tested by PCR and the HPV genotypes were determined by sequencing of PCR amplicons. Transcriptionally-active HPV infections were found in ~25% of the SNSCC cases. The role of HPV infection in keratinizing SNSCC may be higher than previously reported (~32% in our study vs. ~0-6.3% in all other studies). Patients with transcriptionally-active HPV-positive SNSCCs were more likely to be diagnosed at earlier stages (p<0.05) and displayed better mean overall survival, although the difference between HPV-positive and HPV-negative groups was not statistically significant. In contrast to other non-oropharyngeal squamous cell carcinomas (non-OPSCCs) of the head and neck, in SNSCCs, p16/IHC and p16/IHC+HPV DNA displayed high specificity as surrogate markers of transcriptionally-active HPV infections. However, p16/IHC may have significantly lower sensitivity as a surrogate marker of transcriptionally-active HPV in SNSCCs compared to OPSCCs. Furthermore, in our group of SNSCCs, all cases positive for high-risk HPV DNA by PCR were also transcriptionally-active (causative) infections with positive HPV mRNA by ISH. Our results imply a possible different role of HPV-mediated carcinogenesis of squamous cell epithelium in oropharyngeal and sinonasal sites with the latter displaying a lower proportion of causative HPV infections; nevertheless, most cases positive for high-risk HPV DNA, p16/IHC or combination thereof were also found positive for transcriptionally-active HPV. The prognostic significance of HPV status in SNSCCs remains inconclusive and future studies should investigate the presence of transcriptionally-active HPV by direct HPV testing. [ABSTRACT FROM AUTHOR]