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2. Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease

Author

Frikke-Schmidt, Ruth, Stene, Maria C.A., Nordestgaard, Borge G., Sethi, Amar A., Remaley, Alan T., Schnohr, Peter, Grande, Peer, and Tybjaerg-Hansen, Anne

Subjects
Cholesterol, HDL -- Health aspects, Mutation (Biology) -- Analysis, Myocardial ischemia -- Genetic aspects
Abstract

A study to examine whether the mutated gene ABCA1 was responsible for the increased risk of ischemic heart disease (IHD) and enhanced levels of high-density lipoprotein (HDL) cholesterol levels is conducted. Results reveal that the mutated gene did not have any effect of increased risk of IHD and HDL.

Published
2008

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