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1. CEA (CEACAM5) expression is common in muscle‐invasive urothelial carcinoma of the bladder but unrelated to the disease course

Author: Henning Plage, Kira Furlano, Jörg Neymeyer, Sarah Weinberger, Benedikt Gerdes, Mandy Hubatsch, Bernhard Ralla, Antonia Franz, Annika Fendler, Michela deMartino, Florian Roßner, Simon Schallenberg, Sefer Elezkurtaj, Martina Kluth, Maximilian Lennartz, Niclas C. Blessin, Andreas H. Marx, Henrik Samtleben, Margit Fisch, Michael Rink, Krystian Kaczmarek, Thorsten Ecke, Steffen Hallmann, Stefan Koch, Nico Adamini, Sarah Minner, Ronald Simon, Guido Sauter, Joachim Weischenfeldt, Tobias Klatte, Thorsten Schlomm, David Horst, Henrik Zecha, and Marcin Slojewski
Subjects: bladder cancer, CEA, CEACAM5, immunohistochemistry, prognosis, tissue microarray, Diseases of the genitourinary system. Urology, RC870-923
Abstract: Abstract Objectives Carcinoembryonic antigen (CEA) is a cell surface glycoprotein that represents a promising therapeutic target. Serum measurement of shedded CEA can be utilized for monitoring of cancer patients. Material and Methods To evaluate the potential clinical significance of CEA expression in urothelial bladder neoplasms, CEA was analysed by immunohistochemistry in more than 2500 urothelial bladder carcinomas in a tissue microarray format. Results CEA staining was largely absent in normal urothelial cells but was observed in 30.4% of urothelial bladder carcinomas including 406 (16.7%) with weak, 140 (5.8%) with moderate, and 192 (7.9%) with strong staining. CEA positivity occurred in 10.9% of 411 pTaG2 low‐grade, 32.0% of 178 pTaG2 high‐grade, and 43.0% of 93 pTaG3 tumours (p 0.25). Conclusion CEA increases markedly with grade progression in pTa tumours, and expression occurs in a significant fraction of pT2–4 urothelial bladder carcinomas. The high rate of CEA positivity in pT2–4 carcinomas offers the opportunity of using CEA serum measurement for monitoring the clinical course of these cancers. Moreover, CEA positive urothelial carcinomas are candidates for a treatment by targeted anti‐CEA drugs.
Published: 2024
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2. PD-L1 expression in tumor and inflammatory cells is associated with favorable tumor features and favorable prognosis in muscle-invasive urothelial carcinoma of the bladder not treated by immune checkpoint inhibitors

Author: Henning Plage, Kira Furlano, Sebastian Hofbauer, Sarah Weinberger, Bernhard Ralla, Antonia Franz, Annika Fendler, Michela de Martino, Florian Roßner, Sefer Elezkurtaj, Martina Kluth, Maximilian Lennartz, Niclas C. Blessin, Andreas H. Marx, Henrik Samtleben, Margit Fisch, Michael Rink, Marcin Slojewski, Krystian Kaczmarek, Thorsten Ecke, Steffen Hallmann, Stefan Koch, Nico Adamini, Henrik Zecha, Sarah Minner, Ronald Simon, Guido Sauter, Joachim Weischenfeldt, Tobias Klatte, Thorsten Schlomm, David Horst, and Simon Schallenberg
Subjects: PD-L1, Urothelial bladder carcinomas, Tissue microarray, Immunohistochemistry, Diseases of the genitourinary system. Urology, RC870-923
Abstract: Abstract Background A high level of PD-L1 expression is the most relevant predictive parameter for response to immune checkpoint inhibitor (CPI) therapy in urinary bladder cancer. Existing data on the relationship between PD-L1 expression and the natural course of disease are controversial and sparse. Methods To expand our understanding of the relationship between PD-L1 expression and parameters of cancer aggressiveness, PD-L1 was analyzed on tissue microarrays containing 2710 urothelial bladder carcinomas including 512 patients with follow-up data who underwent radical cystectomy and follow-up therapies in the pre-immune checkpoint inhibitor therapy era. Results Tumor cell positivity in ≥10% of cells were seen in 513 (20%) and an immune cell positivity occurred in 872 (34%) of 2566 interpretable cancers. PD-L1 positivity in tumor cells increased from pTaG2 low grade (0.9% positive) to pTaG3 high grade (4.1%; p = 0.0255) and was even higher in muscle-invasive (pT2–4) carcinomas (29.3%; p
Published: 2024
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3. Loss of TROP2 and epithelial cell adhesion molecule expression is linked to grade progression in pTa but unrelated to disease outcome in pT2-4 urothelial bladder carcinomas

Author: Jan H. Müller, Henning Plage, Sefer Elezkurtaj, Tim Mandelkow, Zhihao Huang, Magalie C. J. Lurati, Jonas B. Raedler, Nicolaus F. Debatin, Eik Vettorazzi, Henrik Samtleben, Sebastian Hofbauer, Kira Furlano, Jörg Neymeyer, Irena Goranova, Bernhard Ralla, Sarah Weinberger, David Horst, Florian Roßner, Simon Schallenberg, Andreas H. Marx, Margit Fisch, Michael Rink, Marcin Slojewski, Krystian Kaczmarek, Thorsten Ecke, Steffen Hallmann, Stefan Koch, Nico Adamini, Maximilian Lennartz, Sarah Minner, Ronald Simon, Guido Sauter, Henrik Zecha, Thorsten Schlomm, and Elena Bady
Subjects: TROP2, EpCAM, muscle invasive urothelial cancer, multiplex fluorescence immunohistochemistry, bladder cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: IntroductionTrophoblast cell surface antigen 2 (TROP2; EpCAM2) is a transmembrane glycoprotein which is closely related to EpCAM (EpCAM; EpCAM1). Both proteins share partial overlapping functions in epithelial development and EpCAM expression but have not been comparatively analyzed together in bladder carcinomas. TROP2 constitutes the target for the antibody-drug conjugate Sacituzumab govitecan (SG; TrodelvyTM) which has been approved for treatment of metastatic urothelial carcinoma by the United States Food and Drug administration (FDA) irrespective of its TROP2 expression status. MethodsTo evaluate the potential clinical significance of subtle differences in TROP2 and EpCAM expression in urothelial bladder cancer, both proteins were analyzed by multiplex fluorescence immunohistochemistry in combination with a deep-learning based algorithm for automated cell detection on more than 2,700 urothelial bladder carcinomas in a tissue microarray (TMA) format. ResultsThe staining pattern of TROP2 and EpCAM were highly similar. For both proteins, the staining intensity gradually decreased from pTa G2 low grade (TROP2: 68.8±36.1; EpCAM: 21.5±11.7) to pTa G2 high grade (64.6±38.0; 19.3±12.2) and pTa G3 (52.1±38.7; 16.0±13.0, p
Published: 2024
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4. Identifying the Molecular Mechanisms Contributing to Progression, Metastasis, and Death in Low-grade Non–muscle-invasive Bladder Cancer: A Case Report

Author: Sarah Weiß, Steffen Hallmann, Stefan Koch, Sebastian Eidt, Robert Stoehr, Elke Veltrup, Jenny Roggisch, Ralph M. Wirtz, and Thorsten H. Ecke
Subjects: Non–muscle-invasive bladder cancer, Luminal subtype, FGFR3, ERBB2, KRT20, Metastasis, Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Transitional cell carcinoma of the bladder is a common malignancy with an estimated 549 393 new cases occurring in 2018 alone. Both non–muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC) show high recurrence and progression rates, and therefore impose a great burden on patients and health care systems. Current risk stratification and therapy strategies are predominantly based on clinical and histopathological findings for tumor stage and grade. The chemoresistance and metastasis of low-grade tumors suggest an incomplete understanding of disease mechanisms, despite numerous studies on differentiating molecular subtypes of bladder cancer to identify tumor drivers and potential therapeutic targets. We present a highly unusual course for a low-grade bladder tumor leading to metastasis and death, for which we used postmortem histopathological and molecular analyses to evaluate targetable alterations in key signaling pathways driving the underlying tumor biology.
Published: 2021
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5. Health-related quality of life and rates of toxicity after high-dose-rate brachytherapy in combination with external beam radiation therapy for high-risk prostate cancer

Author: Hui-Juan Huang-Tiel, Isabella Otto, Klaus Golka, Silvia Selinski, Stephan Koswig, Kathrin Bathe, Steffen Hallmann, and Thorsten H. Ecke
Subjects: brachytherapy, prostatic neoplasms, quality of life, radiotherapy, Diseases of the genitourinary system. Urology, RC870-923
Abstract: Purpose: High-dose-rate brachytherapy (HDR-BT) with external beam radiation therapy (EBRT) is a common treatment option for locally advanced prostate cancer. Quality of life is an important factor when discussing therapy options for high-risk prostate cancer. This study evaluated adverse effects and health-related quality of life (HRQOL). Materials and Methods: Ninety male patients (median age, 71 years; range, 50 to 79 years) with high-risk prostate cancer underwent HDR-BT after EBRT between December 2009 and January 2017 with a median follow-up of 43 months. A total of 57 patients (69.5%) answered the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life of Cancer Patients questionnaire (QLQ-C30; ver. 3.0), and 8 patients died during follow-up. In order to put the results of this study in context, we compared the results with reference data from the EORTC QLQ-C30 Scoring Manual. Correlations of prostate-specific antigen (PSA) values, International Prostate Symptom Score, and HRQOL measures were calculated. Results: The study participants reported better physical functioning and better global health compared with the reference data, but worse social, role, and cognitive functioning. We found negative statistically significant correlations between the last-measured PSA value and social functioning (p>0.01), cognitive functioning, pain, and constipation (all p
Published: 2020
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6. Prediction of Response to Cisplatin-Based Neoadjuvant Chemotherapy of Muscle-Invasive Bladder Cancer Patients by Molecular Subtyping including KRT and FGFR Target Gene Assessment

Author: Thorsten H. Ecke, Paula Carolin Voß, Thorsten Schlomm, Anja Rabien, Frank Friedersdorff, Dimitri Barski, Thomas Otto, Michael Waldner, Elke Veltrup, Friederike Linden, Roland Hake, Sebastian Eidt, Jenny Roggisch, Axel Heidenreich, Constantin Rieger, Lucas Kastner, Steffen Hallmann, Stefan Koch, and Ralph M. Wirtz
Subjects: bladder cancer, neoadjuvant chemotherapy, FGFR1, FGFR3, KRT5, KRT20, Biology (General), QH301-705.5, Chemistry, QD1-999
Abstract: Patients with muscle-invasive urothelial carcinoma achieving pathological complete response (pCR) upon neoadjuvant chemotherapy (NAC) have improved prognosis. Molecular subtypes of bladder cancer differ markedly regarding sensitivity to cisplatin-based chemotherapy and harbor FGFR treatment targets to various content. The objective of the present study was to evaluate whether preoperative assessment of molecular subtype as well as FGFR target gene expression is predictive for therapeutic outcome—rate of ypT0 status—to justify subsequent prospective validation within the “BladderBRIDGister”. Formalin-fixed paraffin-embedded (FFPE) tissue specimens from transurethral bladder tumor resections (TUR) prior to neoadjuvant chemotherapy and corresponding radical cystectomy samples after chemotherapy of 36 patients were retrospectively collected. RNA from FFPE tissues were extracted by commercial kits, Relative gene expression of subtyping markers (e.g., KRT5, KRT20) and target genes (FGFR1, FGFR3) was analyzed by standardized RT-qPCR systems (STRATIFYER Molecular Pathology GmbH, Cologne). Spearman correlation, Kruskal–Wallis, Mann–Whitney and sensitivity/specificity tests were performed by JMP 9.0.0 (SAS software). The neoadjuvant cohort consisted of 36 patients (median age: 69, male 83% vs. female 17%) with 92% of patients being node-negative during radical cystectomy after 1 to 4 cycles of NAC. When comparing pretreatment with post-treatment samples, the median expression of KRT20 dropped most significantly from DCT 37.38 to 30.65, which compares with a 128-fold decrease. The reduction in gene expression was modest for other luminal marker genes (GATA3 6.8-fold, ERBB2 6.3-fold). In contrast, FGFR1 mRNA expression increased from 33.28 to 35.88 (~6.8-fold increase). Spearman correlation revealed positive association of pretreatment KRT20 mRNA levels with achieving pCR (r = 0.3072: p = 0.0684), whereas pretreatment FGFR1 mRNA was associated with resistance to chemotherapy (r = −0.6418: p < 0.0001). Hierarchical clustering identified luminal tumors of high KRT20 mRNA expression being associated with high pCR rate (10/16; 63%), while the double-negative subgroup with high FGFR1 expression did not respond with pCR (0/9; 0%). Molecular subtyping distinguishes patients with high probability of response from tumors as resistant to neoadjuvant chemotherapy. Targeting FGFR1 in less-differentiated bladder cancer subgroups may sensitize tumors for adopted treatments or subsequent chemotherapy.
Published: 2022
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7. UBC Test for detection of carcinoma in situ for bladder cancer

Author: Thorsten H Ecke, Sarah Weiß, Carsten Stephan, Steffen Hallmann, Dimitri Barski, Thomas Otto, and Holger Gerullis
Subjects: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: UBC ® Rapid Test is a test that detects fragments of cytokeratins 8 and 18 in urine. We present results of a multicentre study measuring UBC ® Rapid Test in bladder cancer patients and healthy controls with focus on carcinoma in situ (CIS) and high-grade bladder cancer. From our study with N = 452 patients, we made a stratified sub-analysis for carcinoma in situ of the urinary bladder. Clinical urine samples were used from 87 patients with tumours of the urinary bladder (23 carcinoma in situ, 23 non-muscle-invasive low-grade tumours, 21 non-muscle-invasive high-grade tumours and 20 muscle-invasive high-grade tumours) and from 22 healthy controls. The cut-off value was defined at 10.0 µg/L. Urine samples were analysed by the UBC ® Rapid Test point-of-care system (concile Omega 100 POC reader). Pathological levels of UBC Rapid Test in urine are higher in patients with bladder cancer in comparison to the control group (p < 0.001). Sensitivity was calculated at 86.9% for carcinoma in situ, 30.4% for non-muscle-invasive low-grade bladder cancer, 71.4% for nonmuscle-invasive high grade bladder cancer and 60% for muscle-invasive high-grade bladder cancer, and specificity was 90.9%. The area under the curve of the quantitative UBC ® Rapid Test using the optimal threshold obtained by receiveroperated curve analysis was 0.75. Pathological values of UBC ® Rapid Test in urine are higher in patients with high-grade bladder cancer in comparison to low-grade tumours and the healthy control group. UBC ® Rapid Test has potential to be more sensitive and specific urinary protein biomarker for accurate detection of high-grade patients and could be added especially in the diagnostics for carcinoma in situ and non-muscle-invasive high-grade tumours of urinary bladder cancer.
Published: 2017
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8. UBC® Rapid Test—A Urinary Point-of-Care (POC) Assay for Diagnosis of Bladder Cancer with a focus on Non-Muscle Invasive High-Grade Tumors: Results of a Multicenter-Study

Author: Thorsten H. Ecke, Sarah Weiß, Carsten Stephan, Steffen Hallmann, Christian Arndt, Dimitri Barski, Thomas Otto, and Holger Gerullis
Subjects: bladder cancer, tumor markers, urinary based diagnostics, Biology (General), QH301-705.5, Chemistry, QD1-999
Abstract: Objectives: UBC® Rapid Test measures soluble fragments of cytokeratins 8 and 18 in urine. We present results of a multicenter study using an updated version of UBC® Rapid Test in bladder cancer patients, patients with urinary bladder cancer positive history, and healthy controls. Material and Methods: In total 530 urine samples have been included in this study. Clinical urine samples were used from 242 patients with tumors of the urinary bladder (134 non-muscle-invasive low-grade tumors (NMI-LG), 48 non-muscle-invasive high-grade tumors (NMI-HG), and 60 muscle-invasive high-grade tumors (MI-HG)), 62 patients with non-evidence of disease (NED), and 226 healthy controls. Urine samples were analyzed by the UBC® Rapid point-of-care (POC) assay and evaluated by Concile Omega 100 POC Reader. All statistical analyses have been performed using R version 3.2.3. Results: Elevated levels of UBC® Rapid Test in urine are higher in patients with bladder cancer in comparison to the control group (p < 0.001). The sensitivity for the whole bladder cancer cohort was 53.3% (positive predictive value (PPV) 90.2%, negative predictive value (NPV) 65.2%) and was 38.8% (PPV 78.8%, NPV 72.1%) for non-muscle-invasive low-grade bladder cancer; 75.0% (PPV 72.0%, NPV 94.7%) for non-muscle-invasive high-grade bladder cancer and 68.3% (PPV 74.6%, NPV 91.8%) for muscle-invasive high-grade bladder cancer. The specificity for the statistical calculations was 93.8%. The cut-off value (10 µg/L) was evaluated for the whole patient cohort. The area under the curve of the quantitative UBC® Rapid Test using the optimal threshold obtained by receiver operating characteristics (ROC) analysis was 0.774. Elevated values of UBC® Rapid Test in urine are higher in patients with high-grade bladder cancer in comparison to low-grade tumors and the healthy control group. Conclusions: UBC® Rapid Test has potential to be a clinically valuable urinary protein biomarker for detection of high-grade bladder cancer patients and could be added in the management of NMI-HG tumors. UBC® Rapid results generated in both study centers in the present multicenter study are very similar and reproducible. Furthermore UBC® Rapid Test is standardized and calibrated and thus independent of used batch of test as well as study site.
Published: 2018
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9. Prostate Specific Antigen (PSA) as Predicting Marker for Clinical Outcome and Evaluation of Early Toxicity Rate after High-Dose Rate Brachytherapy (HDR-BT) in Combination with Additional External Beam Radiation Therapy (EBRT) for High Risk Prostate Cancer

Author: Thorsten H. Ecke, Hui-Juan Huang-Tiel, Klaus Golka, Silvia Selinski, Berit Christine Geis, Stephan Koswig, Katrin Bathe, Steffen Hallmann, and Holger Gerullis
Subjects: PSA, toxicity, HDR brachytherapy, prostate cancer, Biology (General), QH301-705.5, Chemistry, QD1-999
Abstract: High-dose-rate brachytherapy (HDR-BT) with external beam radiation therapy (EBRT) is a common treatment option for locally advanced prostate cancer (PCa). Seventy-nine male patients (median age 71 years, range 50 to 79) with high-risk PCa underwent HDR-BT following EBRT between December 2009 and January 2016 with a median follow-up of 21 months. HDR-BT was administered in two treatment sessions (one week interval) with 9 Gy per fraction using a planning system and the Ir192 treatment unit GammaMed Plus iX. EBRT was performed with CT-based 3D-conformal treatment planning with a total dose administration of 50.4 Gy with 1.8 Gy per fraction and five fractions per week. Follow-up for all patients was organized one, three, and five years after radiation therapy to evaluate early and late toxicity side effects, metastases, local recurrence, and prostate-specific antigen (PSA) value measured in ng/mL. The evaluated data included age, PSA at time of diagnosis, PSA density, BMI (body mass index), Gleason score, D’Amico risk classification for PCa, digital rectal examination (DRE), PSA value after one/three/five year(s) follow-up (FU), time of follow-up, TNM classification, prostate volume, and early toxicity rates. Early toxicity rates were 8.86% for gastrointestinal, and 6.33% for genitourinary side effects. Of all treated patients, 84.81% had no side effects. All reported complications in early toxicity were grade 1. PSA density at time of diagnosis (p = 0.009), PSA on date of first HDR-BT (p = 0.033), and PSA on date of first follow-up after one year (p = 0.025) have statistical significance on a higher risk to get a local recurrence during follow-up. HDR-BT in combination with additional EBRT in the presented design for high-risk PCa results in high biochemical control rates with minimal side-effects. PSA is a negative predictive biomarker for local recurrence during follow-up. A longer follow-up is needed to assess long-term outcome and toxicities.
Published: 2016
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10. Radiofrequency ice dielectric measurements at Summit Station, Greenland

Author: Juan Antonio Aguilar, Patrick Allison, Dave Besson, Abby Bishop, Olga Botner, Sjoerd Bouma, Stijn Buitink, Maddalena Cataldo, Brian A. Clark, Kenny Couberly, Zach Curtis-Ginsberg, Paramita Dasgupta, Simon de Kockere, Krijn D. de Vries, Cosmin Deaconu, Michael A. DuVernois, Anna Eimer, Christian Glaser, Allan Hallgren, Steffen Hallmann, Jordan Christian Hanson, Bryan Hendricks, Jakob Henrichs, Nils Heyer, Christian Hornhuber, Kaeli Hughes, Timo Karg, Albrecht Karle, John L. Kelley, Michael Korntheuer, Marek Kowalski, Ilya Kravchenko, Ryan Krebs, Robert Lahmann, Uzair Latif, Joseph Mammo, Matthew J. Marsee, Zachary S. Meyers, Kelli Michaels, Katharine Mulrey, Marco Muzio, Anna Nelles, Alexander Novikov, Alisa Nozdrina, Eric Oberla, Bob Oeyen, Ilse Plaisier, Noppadol Punsuebsay, Lilly Pyras, Dirk Ryckbosch, Olaf Scholten, David Seckel, Mohammad Ful Hossain Seikh, Daniel Smith, Jethro Stoffels, Daniel Southall, Karen Terveer, Simona Toscano, Delia Tosi, Dieder J. Van Den Broeck, Nick van Eijndhoven, Abigail G. Vieregg, Janna Z. Vischer, Christoph Welling, Dawn R. Williams, Stephanie Wissel, Robert Young, and Adrian Zink
Subjects: Arctic glaciology, ice physics, radio-echo sounding, Environmental sciences, GE1-350, Meteorology. Climatology, QC851-999
Abstract: We recently reported on the radio-frequency attenuation length of cold polar ice at Summit Station, Greenland, based on bi-static radar measurements of radio-frequency bedrock echo strengths taken during the summer of 2021. Those data also allow studies of (a) the relative contributions of coherent (such as discrete internal conducting layers with sub-centimeter transverse scale) vs incoherent (e.g. bulk volumetric) scattering, (b) the magnitude of internal layer reflection coefficients, (c) limits on signal propagation velocity asymmetries (‘birefringence’) and (d) limits on signal dispersion in-ice over a bandwidth of ~100 MHz. We find that (1) attenuation lengths approach 1 km in our band, (2) after averaging 10 000 echo triggers, reflected signals observable over the thermal floor (to depths of ~1500 m) are consistent with being entirely coherent, (3) internal layer reflectivities are ≈–60$\to$–70 dB, (4) birefringent effects for vertically propagating signals are smaller by an order of magnitude relative to South Pole and (5) within our experimental limits, glacial ice is non-dispersive over the frequency band relevant for neutrino detection experiments.
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11. Cytokeratin 20 expression is linked to stage progression and to poor prognosis in advanced (pT4) urothelial carcinoma of the bladder

Author: Paul Giacomo Bruch, Henning Plage, Sebastian Hofbauer, Kira Kornienko, Sarah Weinberger, Florian Roßner, Simon Schallenberg, Martina Kluth, Maximilian Lennartz, Niclas C. Blessin, Andreas H. Marx, Henrik Samtleben, Margit Fisch, Michael Rink, Marcin Slojewski, Krystian Kaczmarek, Thorsten Ecke, Steffen Hallmann, Stefan Koch, Nico Adamini, Sarah Minner, Ronald Simon, Guido Sauter, Henrik Zecha, Tobias Klatte, Thorsten Schlomm, David Horst, and Sefer Elezkurtaj
Subjects: Clinical Biochemistry, Molecular Biology, Pathology and Forensic Medicine
Published: 2023

12. Luminophore Chemistry for Detection of Urinary Bladder Cancer - Comparison to Cytology and Urinary Rapid Tests (BTA stat

Author: Thorsten H, Ecke, Mikolaj, Scislowski, Nazia, Hassan, Mari, Saura, Steffen, Hallmann, Stefan, Koch, Sari, Vuolle, Morteza, Malakoutikhah, Kari, Kopra, and Harri, Härmä
Subjects: Carcinoma, Transitional Cell, Europium, Urinary Bladder Neoplasms, Biomarkers, Tumor, Humans, Terbium, Sensitivity and Specificity, Retrospective Studies
Abstract: New luminometric chelates were developed for the detection of urinary bladder cancer and compared to cytology and urinary rapid tests BTA statThis single-center study analyzed urine from two different cohorts: Firstly, a retrospective pilot cohort (n=27) and secondly a prospective validation cohort (n=60) including patients with bladder cancer and healthy controls. The samples were studied with nine different terbium and europium chelates to detect cancer cases. After identification of an efficient luminophore in the first cohort, the second validation cohort was run with the selected chelates to re-evaluate the results and compare them with urinary rapid tests and cytology.The compared methods showed area under the curve (AUC) values ranging from 0.567 to 0.767. TbEvaluation of terbium and europium chelates for the detection of urinary bladder cancer showed highest specificity among all methods and improved overall performance (characterized by AUC) compared to commercial urine-based rapid tests and cytology. The Eu-probe has the potential to be clinically valuable in urine-based detection of bladder cancer, especially for high-grade cancer.
Published: 2022

13. GATA3 expression loss is linked to stage progression but is unrelated to prognosis in muscle-invasive urothelial carcinoma of the bladder

Author: Henning Plage, Henrik Samtleben, Sebastian Hofbauer, Kira Kornienko, Sarah Weinberger, Paul Giacomo Bruch, Sefer Elezkurtaj, Florian Roßner, Simon Schallenberg, Martina Kluth, Maximilian Lennartz, Niclas C. Blessin, Andreas H. Marx, Margit Fisch, Michael Rink, Marcin Slojewski, Krystian Kaczmarek, Thorsten Ecke, Steffen Hallmann, Stefan Koch, Nico Adamini, Sarah Minner, Ronald Simon, Guido Sauter, Tobias Klatte, Thorsten Schlomm, David Horst, and Henrik Zecha
Subjects: Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Muscles, Urinary Bladder, Biomarkers, Tumor, Humans, GATA3 Transcription Factor, Urothelium, Prognosis, Immunohistochemistry, Pathology and Forensic Medicine
Abstract: The transcription factor GATA binding protein 3 (GATA3) is commonly used in surgical pathology as a diagnostic marker to distinguish urothelial carcinomas from other cancer entities. However, the clinical relevance of GATA3 expression in urothelial bladder cancer is not completely clarified. In this study, we investigated GATA3 immunostaining on 2710 urothelial bladder carcinomas on a tissue microarray platform by using two different antibodies to better understand its impact in relation to pathological parameters of disease progression and patient outcome. Nuclear GATA3 immunostaining was regularly seen in normal urothelium and found in 74%/82% of interpretable urothelial neoplasms depending on the antibody used. Within pTa tumors, the rate of GATA3 positive tumors decreased with advancing grade. GATA3 positivity was seen in 98.6%/99.8% of pTaG2 low-grade, 98.6%/100% of pTaG2 high-grade, and 94.9%/99.2% of pTaG3 high-grade tumors (P = .0002). As compared to pTa tumors, GATA3 positivity was markedly less common in muscle-invasive urothelial carcinoma (59.9%/71.6%; P .0001). Within pT2-4 cancers, high-level GATA3 immunostaining was associated with the presence of lymph node metastasis (P = .0034), and blood vessel (P = .0290) or lymphatic invasion (P = .0005) but unrelated to pT stage. GATA3 immunostaining results for both antibodies were not associated with overall survival in 586 patients treated by cystectomy for pT2-4 urothelial carcinoma. The results of our study identify GATA3 expression as a frequent event in noninvasive urothelial carcinomas with favorable tumor features. Loss of GATA3 immunostaining is linked with muscle-invasive disease but is largely unrelated to pathological parameters and patient prognosis.
Published: 2022

14. Model-independent search for neutrino sources with the ANTARES neutrino telescope

Author: C. Donzaud, A. Enzenhöfer, Stéphane Basa, C. Mueller, A. Heijboer, H. Costantini, I. El Bojaddaini, A. Creusot, S. Biagi, P. Coyle, Th. Stolarczyk, A. Mathieu, S. Geißelsöder, M. Kreter, Gisela Anton, J-J. Aubert, C. Perrina, L. Quinn, Daniele Vivolo, Ingo Kreykenbohm, Giorgio Riccobene, H. van Haren, Jörn Wilms, J. Hößl, J.D. Zornoza, Dominique Lefèvre, L. Caramete, B. Baret, T. Grégoire, K. Roensch, C. Sieger, A. Vizzoca, S. Loucatos, T. Pradier, R. Coniglione, E. Leonora, Matthias Kadler, Dominik Elsässer, E. Nezri, S. Bourret, Uli Katz, K. Graf, Yann Hello, Tommaso Chiarusi, S. J. Wagner, M. Jongen, A. Moussa, M. Anghinolfi, R. Gracia Ruiz, T. Michael, G. De Bonis, C. Distefano, D. F. E. Samtleben, T. Seitz, R. Bruijn, Annarita Margiotta, Michel André, D. Turpin, J. Hofestädt, L.A. Fusco, M. Saldaña, V. Bertin, Alexis Coleiro, J. Zúñiga, M. Taiuti, C. W. James, Miguel Ardid, K. Melis, R. Mele, Hervé Glotin, D. Dornic, A. Trovato, M. de Jong, J. Carr, T. Avgitas, J.A. Martínez-Mora, F. Schüssler, Piera Sapienza, A. Gleixner, Juan José Hernández-Rey, M. Tselengidou, Antonio Capone, Maurizio Spurio, I. Salvadori, Steffen Hallmann, Jutta Schnabel, R. Lahmann, V. Van Elewyck, J. Barrios-Martí, A. Sánchez-Losa, Arnauld Albert, Jose Busto, Joao A B Coelho, R. Bormuth, Ivan Felis, C. Lachaud, V. Popa, Marco Circella, Anne Deschamps, Matteo Sanguineti, Oleg Kalekin, D. Kießling, K. Geyer, Antonio Marinelli, G.E. Păvălaş, D. Drouhin, C. Tönnis, C. Racca, Jürgen Brunner, I. Di Palma, C. Vallée, V. Giordano, Giulia Illuminati, S. Galatà, B. Vallage, Paolo Piattelli, M. Marcelin, Y. Tayalati, P. Migliozzi, V. Kulikovskiy, Silvia Celli, M.C. Bouwhuis, C. Pellegrino, Thomas Eberl, M. Lotze, C. Hugon, Antoine Kouchner, Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, Groupe de Recherche en Physique des Hautes Energies (GRPHE), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-IUT de Colmar, Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Géoazur (GEOAZUR 7329), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Université Paris-Sud - Paris 11 (UP11), Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Laboratoire des Sciences de l'Information et des Systèmes (LSIS), Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Arts et Métiers Paristech ENSAM Aix-en-Provence-Centre National de la Recherche Scientifique (CNRS), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Institut méditerranéen d'océanologie (MIO), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPhP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), ANTARES, Albert, A., Andre, M., Anghinolfi, M., Anton, G., Ardid, M., Aubert, J. -J., Avgitas, T., Baret, B., Barrios-Marti, J., Basa, S., Bertin, V., Biagi, S., Bormuth, R., Bourret, S., Bouwhuis, M. C., Bruijn, R., Brunner, J., Busto, J., Capone, A., Caramete, L., Carr, J., Celli, S., Chiarusi, T., Circella, M., Coelho, J. A. B., Coleiro, A., Coniglione, R., Costantini, H., Coyle, P., Creusot, A., Deschamps, A., De Bonis, G., Distefano, C., Di Palma, I., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., El Bojaddaini, I., Elsasser, D., Enzenhofer, A., Felis, I., Fusco, L. A., Galata, S., Gay, P., Geisselsoder, S., Geyer, K., Giordano, V., Gleixner, A., Glotin, H., Gregoire, T., Gracia Ruiz, R., Graf, K., Hallmann, S., van Haren, H., Heijboer, A. J., Hello, Y., Hernandez-Rey, J. J., Hossl, J., Hofestadt, J., Hugon, C., Illuminati, G., James, C. W., de Jong, M., Jongen, M., Kadler, M., Kalekin, O., Katz, U., Kiessling, D., Kouchner, A., Kreter, M., Kreykenbohm, I., Kulikovskiy, V., Lachaud, C., Lahmann, R., Lefevre, D., Leonora, E., Lotze, M., Loucatos, S., Marcelin, M., Margiotta, A., Marinelli, A., Martinez-Mora, J. A., Mathieu, A., Mele, R., Melis, K., Michael, T., Migliozzi, P., Moussa, A., Mueller, C., Nezri, E., Pavalas, G. E., Pellegrino, C., Perrina, C., Piattelli, P., Popa, V., Pradier, T., Quinn, L., Racca, C., Riccobene, G., Roensch, K., Sanchez-Losa, A., Saldana, M., Salvadori, I., Samtleben, D. F. E., Sanguineti, M., Sapienza, P., Schnabel, J., Schussler, F., Seitz, T., Sieger, C., Spurio, M., Stolarczyk, T., Taiuti, M., Tayalati, Y., Trovato, A., Tselengidou, M., Turpin, D., Tonnis, C., Vallage, B., Vallee, C., Van Elewyck, V., Vivolo, D., Vizzoca, A., Wagner, S., Wilms, J., Zornoza, J. D., Zuniga, J., Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut Universitaire de Technologie de Colmar, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Centre National de la Recherche Scientifique (CNRS)-Arts et Métiers Paristech ENSAM Aix-en-Provence-Université de Toulon (UTLN)-Aix Marseille Université (AMU), Département de Physique des Particules (ex SPP) (DPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Albert A., Andre M., Anghinolfi M., Anton G., Ardid M., Aubert J.-J., Avgitas T., Baret B., Barrios-Marti J., Basa S., Bertin V., Biagi S., Bormuth R., Bourret S., Bouwhuis M.C., Bruijn R., Brunner J., Busto J., Capone A., Caramete L., Carr J., Celli S., Chiarusi T., Circella M., Coelho J.A.B., Coleiro A., Coniglione R., Costantini H., Coyle P., Creusot A., Deschamps A., De Bonis G., Distefano C., Di Palma I., Donzaud C., Dornic D., Drouhin D., Eberl T., El Bojaddaini I., Elsasser D., Enzenhofer A., Felis I., Fusco L.A., Galata S., Gay P., Geisselsoder S., Geyer K., Giordano V., Gleixner A., Glotin H., Gregoire T., Gracia Ruiz R., Graf K., Hallmann S., van Haren H., Heijboer A.J., Hello Y., Hernandez-Rey J.J., Hossl J., Hofestadt J., Hugon C., Illuminati G., James C.W., de Jong M., Jongen M., Kadler M., Kalekin O., Katz U., Kiessling D., Kouchner A., Kreter M., Kreykenbohm I., Kulikovskiy V., Lachaud C., Lahmann R., Lefevre D., Leonora E., Lotze M., Loucatos S., Marcelin M., Margiotta A., Marinelli A., Martinez-Mora J.A., Mathieu A., Mele R., Melis K., Michael T., Migliozzi P., Moussa A., Mueller C., Nezri E., Pavalas G.E., Pellegrino C., Perrina C., Piattelli P., Popa V., Pradier T., Quinn L., Racca C., Riccobene G., Roensch K., Sanchez-Losa A., Saldana M., Salvadori I., Samtleben D.F.E., Sanguineti M., Sapienza P., Schnabel J., Schussler F., Seitz T., Sieger C., Spurio M., Stolarczyk T., Taiuti M., Tayalati Y., Trovato A., Tselengidou M., Turpin D., Tonnis C., Vallage B., Vallee C., Van Elewyck V., Vivolo D., Vizzoca A., Wagner S., Wilms J., Zornoza J.D., Zuniga J., Albert, A, Andre, M, Anghinolfi, M, Anton, G, Ardid, M, Aubert, Jj, Avgitas, T, Baret, B, Barrios-Marti, J, Basa, S, Bertin, V, Biagi, S, Bormuth, R, Bourret, S, Bouwhuis, Mc, Bruijn, R, Brunner, J, Busto, J, Capone, A, Caramete, L, Carr, J, Celli, S, Chiarusi, T, Circella, M, Coelho, Jab, Coleiro, A, Coniglione, R, Costantini, H, Coyle, P, Creusot, A, Deschamps, A, De Bonis, G, Distefano, C, Di Palma, I, Donzaud, C, Dornic, D, Drouhin, D, Eberl, T, Bojaddaini, I, Elsasser, D, Enzenhofer, A, Felis, I, Fusco, La, Galata, S, Gay, P, Geisselsoder, S, Geyer, K, Giordano, V, Gleixner, A, Glotin, H, Gregoire, T, Ruiz, Rg, Graf, K, Hallmann, S, van Haren, H, Heijboer, Aj, Hello, Y, Hernandez-Rey, Jj, Hossl, J, Hofestadt, J, Hugon, C, Illuminati, G, James, Cw, de Jong, M, Jongen, M, Kadler, M, Kalekin, O, Katz, U, Kiessling, D, Kouchner, A, Kreter, M, Kreykenbohm, I, Kulikovskiy, V, Lachaud, C, Lahmann, R, Lefevre, D, Leonora, E, Lotze, M, Loucatos, S, Marcelin, M, Margiotta, A, Marinelli, A, Martinez-Mora, Ja, Mathieu, A, Mele, R, Melis, K, Michael, T, Migliozzi, P, Moussa, A, Mueller, C, Nezri, E, Pavalas, Ge, Pellegrino, C, Perrina, C, Piattelli, P, Popa, V, Pradier, T, Quinn, L, Racca, C, Riccobene, G, Roensch, K, Sanchez-Losa, A, Saldana, M, Salvadori, I, Samtleben, Dfe, Sanguineti, M, Sapienza, P, Schnabel, J, Schussler, F, Seitz, T, Sieger, C, Spurio, M, Stolarczyk, T, Taiuti, M, Tayalati, Y, Trovato, A, Tselengidou, M, Turpin, D, Tonnis, C, Vallage, B, Vallee, C, Van Elewyck, V, Vivolo, D, Vizzoca, A, Wagner, S, Wilms, J, Zornoza, Jd, Zuniga, J, KM3NeT (IHEF, IoP, FNWI), Institut Universitaire de Technologie de Colmar-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Clermont Auvergne (UCA)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université de Toulon (UTLN)-Aix Marseille Université (AMU)-Institut de Recherche pour le Développement (IRD), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Aix Marseille Université (AMU)-Centre National d'Études Spatiales [Toulouse] (CNES), Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA), and Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Astrofísica, 85-04, 85-05, 85-08, Solar neutrino, Astrophysics, 01 natural sciences, IceCube, 010303 astronomy & astrophysics, media_common, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), spatial distribution, track data analysis, Astrophysics::Instrumentation and Methods for Astrophysics, Astropartícules, neutrino: detector, Anisotropy, Astroparticle physics, Neutrino astronomy, Pattern recognition, Neutrino detector, Measurements of neutrino speed, Neutrino, Astrophysics - High Energy Astrophysical Phenomena, media_common.quotation_subject, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, Astroparticle physic, emission: model, neutrino: production, 0103 physical sciences, Neutrins, Neutrinos, ANTARES, Telescopis, 010308 nuclear & particles physics, Astronomy and Astrophysics, Solar neutrino problem, neutrino: VHE, Neutrino astrophysics, Sky, Física::Astronomia i astrofísica [Àrees temàtiques de la UPC], FISICA APLICADA, High Energy Physics::Experiment, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Anysotropy, Telescopes
Abstract: [EN] A novel method to analyse the spatial distribution of neutrino candidates recorded with the ANTARES neutrino telescope is introduced, searching for an excess of neutrinos in a region of arbitrary size and shape from any direction in the sky. Techniques originating from the domains of machine learning, pat- tern recognition and image processing are used to purify the sample of neutrino candidates and for the analysis of the obtained skymap. In contrast to a dedicated search for a speci¿c neutrino emission model, this approach is sensitive to a wide range of possible morphologies of potential sources of high-energy neutrino emission. The application of these methods to ANTARES data yields a large-scale excess with a post-trial signi¿cance of 2.5¿ . Applied to public data from IceCube in its IC40 con¿guration, an excess consistent with the results from ANTARES is observed with a post-trial signi¿cance of 2.1¿ ., The authors acknowledge the financial support of the funding agencies: Centre National de la Recherche Scientifique (CNRS), Commissariat a l'energie atomique et aux energies alternatives (CEA), Commission Europeenne (FEDER fund and Marie Curie Program), Institut Universitaire de France (IUF), IdEx program and UnivEarthS Labex program at Sorbonne Paris Cite (ANR-10-LABX-0023 and ANR-11-IDEX-0005-02), Labex OCEVU (ANR-11-LABX-0060) and the A*MIDEX project (ANR-11-IDEX-0001-02), Region Ile-de-France (DIM-ACAV), Region Alsace (contrat CPER), Region Provence-Alpes-Cote d'Azur, Departement du Var and Ville de La Seyne-sur-Mer, France; Bundesministerium fur Bildung und Forschung (BMBF), Germany; Istituto Nazionale di Fisica Nucleare (INFN), Italy; Stichting voor Fundamenteel Onderzoek der Materie (FOM), Nederlandse organisatie voor Wetenschappelijk Onderzoek (NWO), the Netherlands; Council of the President of the Russian Federation for young scientists and leading scientific schools supporting grants, Russia; National Authority for Scientific Research (ANCS), Romania; Ministerio de Economia y Cornpetitividad (MINECO): Plan Estatal de Investigacion (refs. FPA2015-65150-C3-1-P, -2-P and -3-P, (MINECO/FEDER)), Severo Ochoa Centre of Excellence and MultiDark Consolider (MINECO), and Prometeo and Grisolia programs (Generalitat Valenciana), Spain; Ministry of Higher Education, Scientific Research and Professional Training, Morocco. We also acknowledge the technical support of Ifremer, AIM and Foselev Marine for the sea operation and the CC-IN2P3 for the computing facilities.
Published: 2020

15. Nomograms including the UBC® Rapid test to detect primary bladder cancer based on a multicentre dataset

Author: Christina J. Meisl, Pierre I. Karakiewicz, Roland Einarsson, Stefan Koch, Steffen Hallmann, Sarah Weiß, Tammer Hemdan, Per‐Uno Malmström, Johan Styrke, Amir Sherif, Mudhar N. Hasan, Renate Pichler, Gennadi Tulchiner, Joan Palou, Óscar Rodríguez Faba, Jörg Hennenlotter, Arnulf Stenzl, René Ritter, Günter Niegisch, Camilla M. Grunewald, Thorsten Schlomm, Frank Friedersdorff, Dimitri Barski, Thomas Otto, Andreas Gössl, Christian Arndt, Kesavan Esuvaranathan, Nisha R. Kesavan, Zang Zhijiang, Mario W. Kramer, Martin J. P. Hennig, and Thorsten H. Ecke
Subjects: #uroonc, diagnosis, Urology, Medizin, #BladderCancer, nomogram, Nomograms, #blcsm, Urinary Bladder Neoplasms, ROC Curve, urothelial cancer, Risk Factors, Urologi och njurmedicin, UBC (R) Rapid test, Humans, Urology and Nephrology, bladder cancer, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit, Hematuria, logistic model
Abstract: Objectives To evaluate the clinical utility of the urinary bladder cancer antigen test UBC (R) Rapid for the diagnosis of bladder cancer (BC) and to develop and validate nomograms to identify patients at high risk of primary BC. Patients and Methods Data from 1787 patients from 13 participating centres, who were tested between 2012 and 2020, including 763 patients with BC, were analysed. Urine samples were analysed with the UBC (R) Rapid test. The nomograms were developed using data from 320 patients and externally validated using data from 274 patients. The diagnostic accuracy of the UBC (R) Rapid test was evaluated using receiver-operating characteristic curve analysis. Brier scores and calibration curves were chosen for the validation. Biopsy-proven BC was predicted using multivariate logistic regression. Results The sensitivity, specificity, and area under the curve for the UBC (R) Rapid test were 46.4%, 75.5% and 0.61 (95% confidence interval [CI] 0.58-0.64) for low-grade (LG) BC, and 70.5%, 75.5% and 0.73 (95% CI 0.70-0.76) for high-grade (HG) BC, respectively. Age, UBC (R) Rapid test results, smoking status and haematuria were identified as independent predictors of primary BC. After external validation, nomograms based on these predictors resulted in areas under the curve of 0.79 (95% CI 0.72-0.87) and 0.95 (95% CI: 0.92-0.98) for predicting LG-BC and HG-BC, respectively, showing excellent calibration associated with a higher net benefit than the UBC (R) Rapid test alone for low and medium risk levels in decision curve analysis. The R Shiny app allows the results to be explored interactively and can be accessed at www.blucab-index. net. Conclusion The UBC (R) Rapid test alone has limited clinical utility for predicting the presence of BC. However, its combined use with BC risk factors including age, smoking status and haematuria provides a fast, highly accurate and non-invasive tool for screening patients for primary LG-BC and especially primary HG-BC.
Published: 2022

16. Expectations for the high-energy neutrino detection from starburst galaxies with KM3NeT/ARCA

Author: Ibnsalih, W. I., Ambrosone, A., Marinelli, A., Miele, G., Migliozzi, P., Pisanti, O., Sharma, A., Ageron, M., Aiello, S., Albert, A., Alshamsi, M., Alves Garre, S., Aly, Z., Ameli, F., Andre, M., Androulakis, G., Anghinolfi, M., Anguita, M., Anton, G., Ardid, M., Ardid, S., Assal, W., Aublin, J., Bagatelas, C., Baret, B., Basegmez Du Pree, S., Bendahman, M., Benfenati, F., Berbee, E., Den Berg, A. M., Bertin, V., Beurthey, S., Beveren, V., Biagi, S., Billault, M., Bissinger, M., Boettcher, M., Bou Cabo, M., Boumaaza, J., Bouta, M., Boutonnet, C., Bouvet, G., Bouwhuis, M., Bozza, C., Brânzaş, H., Bruijn, R., Brunner, J., Bruno, R., Buis, E., Buompane, R., Busto, J., Caiffi, B., Caillat, L., Calvo, D., Campion, S., Capone, A., Carduner, H., Carretero, V., Castaldi, P., Celli, S., Cereseto, R., Chabab, M., Champion, C., Chau, N., Chen, A., Cherubini, S., Chiarella, V., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Colomer Molla, M., Colonges, S., Coniglione, R., Cosquer, A., Coyle, P., Cresta, M., Creusot, A., Cruz, A., Cuttone, G., D’amico, A., Dallier, R., Martino, B., Palma, M., Di Palma, I., Díaz, A. F., Diego-Tortosa, D., Distefano, C., Domi, A., Donzaud, C., Dornic, D., Dörr, M., Drouhin, D., Eberl, T., Eddyamoui, A., Eeden, T., Eijk, D., El Bojaddaini, I., Eljarrari, H., Elsaesser, D., Enzenhöfer, A., Espinosa, V., Fermani, P., Ferrara, G., Filipović, M. D., Filippini, F., Fransen, J., Fusco, L. A., Gajanana, D., Gal, T., García Méndez, J., Garcia Soto, A., Garçon, E., Garufi, F., Gatius, C., Geißelbrecht, N., Gialanella, L., Giorgio, E., Gozzini, S. R., Gracia, R., Graf, K., Grella, G., Guderian, D., Guidi, C., Guillon, B., Gutiérrez, M., Haefner, J., Steffen Hallmann, Hamdaoui, H., Haren, H., Heijboer, A., Hekalo, A., Hennig, L., Henry, S., Hernández-Rey, J. J., Hofestädt, J., Huang, F., Idrissi Ibnsalih, W., Ilioni, A., Illuminati, G., James, C. W., Janezashvili, D., Jansweijer, P., Jong, M., Jong, P., Jung, B. J., Kadler, M., Kalaczyński, P., Kalekin, O., Katz, U. F., Kayzel, F., Keller, P., Khan Chowdhury, N. R., Kistauri, G., Knaap, F., Kooijman, P., Kouchner, A., Kreter, M., Kulikovskiy, V., Labalme, M., Lagier, P., Lahmann, R., Lamare, P., Lamoureux, M., Larosa, G., Lastoria, C., Laurence, J., Lazo, A., Le Breton, R., Le Guirriec, E., Le Stum, S., Lehaut, G., Leonardi, O., Leone, F., Leonora, E., Lerouvillois, C., Lesrel, J., Lessing, N., Levi, G., Lincetto, M., Lindsey Clark, M., Lipreau, T., Llorens Alvarez, C., Lonardo, A., Longhitano, F., Lopez-Coto, D., Lumb, N., Maderer, L., Majumdar, J., Mańczak, J., Margiotta, A., Marini, A., Markou, C., Martin, L., Martínez-Mora, J. A., Martini, A., Marzaioli, F., Mastroianni, S., Melis, K. W., Migneco, E., Mijakowski, P., Miranda, L. S., Mollo, C. M., Mongelli, M., Moussa, A., Muller, R., Musico, P., Musumeci, M., Nauta, L., Navas, S., Nicolau, C. A., Nkosi, B., Fearraigh, B. Ó, O’sullivan, M., Orlando, A., Ottonello, G., Ottonello, S., Palacios González, J., Papalashvili, G., Papaleo, R., Pastore, C., Păun, A. M., Păvălaş, G. E., Pellegrini, G., Pellegrino, C., Perrin-Terrin, M., Pestel, V., Piattelli, P., Pieterse, C., Poirè, C., Popa, V., Pradier, T., Pratolongo, F., Probst, I., Pühlhofer, G., Pulvirenti, S., Quéméner, G., Randazzo, N., Rapicavoli, A., Razzaque, S., Real, D., Reck, S., Riccobene, G., Rigalleau, L., Romanov, A., Rovelli, A., Royon, J., Salesa Greus, F., Samtleben, D. F. E., Sánchez Losa, A., Sanguineti, M., Santangelo, A., Santonocito, D., Sapienza, P., Schmelling, J., Schnabel, J., Schneider, M. F., Schumann, J., Schutte, H. M., Seneca, J., Sgura, I., Shanidze, R., Sinopoulou, A., Spisso, B., Spurio, M., Stavropoulos, D., Steijger, J., Stellacci, S. M., Taiuti, M., Tatone, F., Tayalati, Y., Tenllado, E., Tézier, D., Thakore, T., Theraube, S., Thiersen, H., Timmer, P., Tingay, S., Tsagkli, S., Tsourapis, V., Tzamariudaki, E., Tzanetatos, D., Valieri, C., Elewyck, V., Vasileiadis, G., Versari, F., Viola, S., Vivolo, D., Wasseige, G., Wilms, J., Wojaczyński, R., Wolf, E., Yousfi, T., Zavatarelli, S., Zegarelli, A., Zito, D., Zornoza, J. D., Zúñiga, J., Zywucka, N., Bianca Keilhauer, Alexander Kappes, Ibnsalih, W. I., Ambrosone, A., Marinelli, A., Miele, G., Migliozzi, P., Pisanti, O., Sharma, A., Ageron, M., Aiello, S., Albert, A., Alshamsi, M., Alves Garre, S., Aly, Z., Ameli, F., Andre, M., Androulakis, G., Anghinolfi, M., Anguita, M., Anton, G., Ardid, M., Ardid, S., Assal, W., Aublin, J., Bagatelas, C., Baret, B., Basegmez du Pree, S., Bendahman, M., Benfenati, F., Berbee, E., van den Berg, A. M., Bertin, V., Beurthey, S., van Beveren, V., Biagi, S., Billault, M., Bissinger, M., Boettcher, M., Bou Cabo, M., Boumaaza, J., Bouta, M., Boutonnet, C., Bouvet, G., Bouwhuis, M., Bozza, C., Branzas, H., Bruijn, R., Brunner, J., Bruno, R., Buis, E., Buompane, R., Busto, J., Caiffi, B., Caillat, L., Calvo, D., Campion, S., Capone, A., Carduner, H., Carretero, V., Castaldi, P., Celli, S., Cereseto, R., Chabab, M., Champion, C., Chau, N., Chen, A., Cherubini, S., Chiarella, V., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Colomer Molla, M., Colonges, S., Coniglione, R., Cosquer, A., Coyle, P., Cresta, M., Creusot, A., Cruz, A., Cuttone, G., D'Amico, A., Dallier, R., De Martino, B., De Palma, M., Di Palma, I., Diaz, A. F., Diego-Tortosa, D., Distefano, C., Domi, A., Donzaud, C., Dornic, D., Dorr, M., Drouhin, D., Eberl, T., Eddyamoui, A., van Eeden, T., van Eijk, D., El Bojaddaini, I., Eljarrari, H., Elsaesser, D., Enzenhofer, A., Espinosa, V., Fermani, P., Ferrara, G., Filipovic, M. D., Filippini, F., Fransen, J., Fusco, L. A., Gajanana, D., Gal, T., Garcia Mendez, J., Garcia Soto, A., Garcon, E., Garufi, F., Gatius, C., Geisselbrecht, N., Gialanella, L., Giorgio, E., Gozzini, S. R., Gracia, R., Graf, K., Grella, G., Guderian, D., Guidi, C., Guillon, B., Gutierrez, M., Haefner, J., Hallmann, S., Hamdaoui, H., van Haren, H., Heijboer, A., Hekalo, A., Hennig, L., Henry, S., Hernandez-Rey, J. J., Hofestadt, J., Huang, F., Idrissi Ibnsalih, W., Ilioni, A., Illuminati, G., James, C. W., Janezashvili, D., Jansweijer, P., de Jong, M., de Jong, P., Jung, B. J., Kadler, M., Kalaczynski, P., Kalekin, O., Katz, U. F., Kayzel, F., Keller, P., Khan Chowdhury, N. R., Kistauri, G., van der Knaap, F., Kooijman, P., Kouchner, A., Kreter, M., Kulikovskiy, V., Labalme, M., Lagier, P., Lahmann, R., Lamare, P., Lamoureux, M., Larosa, G., Lastoria, C., Laurence, J., Lazo, A., Le Breton, R., Le Guirriec, E., Le Stum, S., Lehaut, G., Leonardi, O., Leone, F., Leonora, E., Lerouvillois, C., Lesrel, J., Lessing, N., Levi, G., Lincetto, M., Lindsey Clark, M., Lipreau, T., LLorens Alvarez, C., Lonardo, A., Longhitano, F., Lopez-Coto, D., Lumb, N., Maderer, L., Majumdar, J., Manczak, J., Margiotta, A., Marini, A., Markou, C., Martin, L., Martinez-Mora, J. A., Martini, A., Marzaioli, F., Mastroianni, S., Melis, K. W., Migneco, E., Mijakowski, P., Miranda, L. S., Mollo, C. M., Mongelli, M., Moussa, A., Muller, R., Musico, P., Musumeci, M., Nauta, L., Navas, S., Nicolau, C. A., Nkosi, B., Fearraigh, B. O., O'Sullivan, M., Orlando, A., Ottonello, G., Ottonello, S., Palacios Gonzalez, J., Papalashvili, G., Papaleo, R., Pastore, C., Paun, A. M., Pavalas, G. E., Pellegrini, G., Pellegrino, C., Perrin-Terrin, M., Pestel, V., Piattelli, P., Pieterse, C., Poire, C., Popa, V., Pradier, T., Pratolongo, F., Probst, I., Puhlhofer, G., Pulvirenti, S., Quemener, G., Randazzo, N., Rapicavoli, A., Razzaque, S., Real, D., Reck, S., Riccobene, G., Rigalleau, L., Romanov, A., Rovelli, A., Royon, J., Salesa Greus, F., Samtleben, D. F. E., Sanchez Losa, A., Sanguineti, M., Santangelo, A., Santonocito, D., Sapienza, P., Schmelling, J., Schnabel, J., Schneider, M. F., Schumann, J., Schutte, H. M., Seneca, J., Sgura, I., Shanidze, R., Sinopoulou, A., Spisso, B., Spurio, M., Stavropoulos, D., Steijger, J., Stellacci, S. M., Taiuti, M., Tatone, F., Tayalati, Y., Tenllado, E., Tezier, D., Thakore, T., Theraube, S., Thiersen, H., Timmer, P., Tingay, S., Tsagkli, S., Tsourapis, V., Tzamariudaki, E., Tzanetatos, D., Valieri, C., Van Elewyck, V., Vasileiadis, G., Versari, F., Viola, S., Vivolo, D., de Wasseige, G., Wilms, J., Wojaczynski, R., de Wolf, E., Yousfi, T., Zavatarelli, S., Zegarelli, A., Zito, D., Zornoza, J. D., Zuniga, J., and Zywucka, N.
Abstract: Star-forming galaxies (SFGs) and starburst galaxies (SBGs) are extragalactic sources which could produce high-energy neutrinos. In principle, they could play a rather important role for explaining at least a sizeable part of IceCube’s observations of astophysical neutrino. Using a recent theoretical model which implemented a blending of spectral indeces, we present the KM3NeT/ARCA sensitivities for such a diffuse flux from the startburst galaxies. In particular, we provide the 5-year differential sensitivity for the two building blocks of ARCA. We make use only of the track-like events in the range of 100 GeV - 10 PeV differentiate in 11 bins of energy. We show how the upcoming neutrino telescope could observe the diffuse SFG and SBG within 5 years of data taking. We found the minimum of the sensitivity at around 100 TeV, which is also the energy where the SBG contribution is expected to peak. This would not only constrain the multi-component fit of the observed astrophysical neutrino flux at that energy (100 TeV), but would also provide us a direct link between the star-forming activity in the reservoir environments and the hadronic emissions.
Published: 2022

17. The Radio Neutrino Observatory Greenland (RNO-G)

Author: Zachary S. Meyers, Allan Hallgren, Katie Carter, Anna Nelles, Thomas Meures, Ryan Krebs, Lilly Pyras, Krijn D. de Vries, N. Bingefors, John L. Kelley, Patrick Allison, U. Latif, Benjamin Hokanson-Fasig, Juan A. Aguilar, Dieder J. Van Den Broeck, Simon De Kockere, R. Lahmann, Ilse Plaisier, Stephanie Wissel, David Zeke Besson, Jorge Torres, M. A. DuVernois, Mitchell Magnuson, Simona Toscano, Kaeli Hughes, D. Tosi, Christian Glaser, Maddalena Cataldo, Bob Oeyen, Dirk Ryckbosch, Robert Young, Rno-g, Steffen Hallmann, Cosmin Deaconu, Zachary Curtis-Ginsberg, Daniel Southall, J. J. Beatty, Daniel Smith, Hans Bernhoff, C. Hornhuber, Katharine Mulrey, Paramita Dasgupta, Olga Botner, Sjoerd Bouma, Olaf Scholten, D. Seckel, Brian Clark, Alexander Novikov, Amy Connolly, Christoph Welling, Spencer Klein, Hershal Pandya, Stijn Buitink, Bryan Hendricks, Nick van Eijndhoven, Eric Oberla, A. Karle, Abigail G. Vieregg, Adrian Zink, and Jordan C. Hanson
Subjects: Neutrino detector, Sky, Software deployment, Observatory, Astrophysics::High Energy Astrophysical Phenomena, media_common.quotation_subject, Astrophysics::Instrumentation and Methods for Astrophysics, Environmental science, Astronomy, Instrumentation (computer programming), Neutrino, media_common
Abstract: The Radio Neutrino Observatory Greenland (RNO-G) is scheduled for deployment in the summerof 2021. It will target the detection of astrophysical and cosmogenic neutrinos above 10 PeV. With 35 autonomous stations, it will be the largest implementation of a radio neutrino detector to date.The stations combine best-practice instrumentation from all previous radio neutrino arrays, such as a deep phased-array trigger and surface antennas. These proceedings describe the experimentalconsiderations that have driven the design of RNO-G and the current progress in deployment, aswell as discuss the projected sensitivity of the instrument. RNO-G will provide a unique view ofthe Northern Sky and will also inform the design of the radio component of IceCube-Gen2.
Published: 2021

18. TAROGE-M: radio antenna array on antarctic high mountain for detecting near-horizontal ultra-high energy air showers

Author: Shih-Hao Wang, Jiwoo Nam, Pisin Chen, Yaocheng Chen, Taejin Choi, Young-bae Ham, Shih-Ying Hsu, Jian-Jung Huang, Ming-Huey A. Huang, Geonhwa Jee, Jongil Jung, Jieun Kim, Chung-Yun Kuo, Hyuck-Jin Kwon, Changsup Lee, Chung-Hei Leung, Tsung-Che Liu, Yu-Shao J. Shiao, Bok-Kyun Shin, Min-Zu Wang, Yu-Hsin Wang, Astrid Anker, Steven W. Barwick, Dave Z. Besson, Sjoerd Bouma, Maddalena Cataldo, Geoffrey Gaswint, Christian Glaser, Steffen Hallmann, Jordan C. Hanson, Jakob Henrichs, Stuart A. Kleinfelder, Robert Lahmann, Zachary S. Meyers, Anna Nelles, Alexander Novikov, Manuel P. Paul, Lilly Pyras, Christopher Persichilli, Ilse Plaisier, Ryan Rice-Smith, Mohammad F.H. Seikh, Joulien Tatar, Christoph Welling, and Leshan Zhao
Subjects: Astronomy and Astrophysics
Abstract: The TAROGE-M radio observatory is a self-triggered antenna array on top of the ∼2700 m high Mt. Melbourne in Antarctica, designed to detect impulsive geomagnetic emission from extensive air showers induced by ultra-high energy (UHE) particles beyond 1017 eV, including cosmic rays, Earth-skimming tau neutrinos, and particularly, the “ANITA anomalous events” (AAE) from near and below the horizon. The six AAE discovered by the ANITA experiment have signal features similar to tau neutrinos but that hypothesis is in tension either with the interaction length predicted by Standard Model or with the flux limits set by other experiments. Their origin remains uncertain, requiring more experimental inputs for clarification. The detection concept of TAROGE-M takes advantage of a high altitude with synoptic view toward the horizon as an efficient signal collector, and the radio quietness as well as strong and near vertical geomagnetic field in Antarctica, enhancing the relative radio signal strength. This approach has a low energy threshold, high duty cycle, and is easy to extend for quickly enlarging statistics. Here we report experimental results from the first TAROGE-M station deployed in January 2020, corresponding to approximately one month of livetime. The station consists of six receiving antennas operating at 180–450 MHz, and can reconstruct source directions of impulsive events with an angular resolution of ∼0.3°, calibrated in situ with a drone-borne pulser system. To demonstrate TAROGE-M's ability to detect UHE air showers, a search for cosmic ray signals in 25.3-days of data together with the detection simulation were conducted, resulting in seven identified candidates. The detected events have a mean reconstructed energy of 0.95-0.31 +0.46 EeV and zenith angles ranging from 25° to 82°, with both distributions agreeing with the simulations, indicating an energy threshold at about 0.3 EeV. The estimated cosmic ray flux at that energy is 1.2-0.9 +0.7 × 10-16 eV-1 km-2 yr-1 sr-1, also consistent with results of other experiments. The TAROGE-M sensitivity to AAEs is approximated by the tau neutrino exposure with simulations, which suggests comparable sensitivity as ANITA's at around 1 EeV energy with a few station-years of operation. These first results verified the station design and performance in a polar and high-altitude environment, and are promising for further discovery of tau neutrinos and AAEs after an extension in the near future.
Published: 2022

19. Neutrino non-standard interactions with theKM3NeT/ORCA detector

Author: Maarten De Jong, Ad van den Berg, Nick Lumb, A. Creusot, Gennaro Miele, Giorgio Riccobene, Lucio Gialanella, Nunzio Randazzo, Giuseppe Levi, F. Filippini, Frits van der Knaap, Steven Tingay, Domenico Santonocito, Alba Domi, D. Calvo, Clara Gatius Oliver, Piera Sapienza, Evelyne Garcon, V. Popa, Steffen Hallmann, Tommaso Chiarusi, Paolo Piattelli, J. Brunner, R. Coniglione, Silvia Celli, A. Sinopoulou, Gerd Puehlhofer, Richard Dallier, S. Biagi, Daan van Eijk, Emanuele Leonora, J.D. Zornoza, Manuel Bou Cabo, Fabio Longhitano, Sandra Zavatarelli, Alessandro Lonardo, D. Gajanana, Jihad Boumaaza, Bianca De Martino, Nadja Lessing, Luis Salvador Miranda Palacios, Soebur Razzaque, Jutta Schnabel, Daniele Vivolo, Davit Janezashvili, M. Taiuti, Emmanuel Le Guirriec, Carlos Maximiliano Mollo, Ankur Sharma, S. Reck, Matthias Bissinger, Horea Branzas, Thomas Eberl, Chiara Filomena Lastoria, Mohamed Chabab, Francesco Benfenati, S. Colonges, J.A. Martínez-Mora, Alexis Coleiro, Gilles Quemener, Hannes Thiersen, Bhuti Nkosi, Stefano Ottonello, R. Muller, Fabrizio Ameli, Sergio Alves Garre, Nhan Chau, Emilio Migneco, Gwenhaël de Wasseige, Mario Musumeci, S. R. Gozzini, Bouke Jisse Jung, Alfonso Lazo, Thierry Pradier, Emidio Giorgio, D. Guderian, Piotr Mijakowski, Tarik Yousfi, Massimiliano Cresta, V. Carretero, S. Henry, Kay Graf, Karel Melis, P. Keller, Piotr Kalaczyński, A. D'Amico, Gregory Lehaut, A. Cosquer, Giovanna Ferrara, Angelo Orlando, Carmelo Pellegrino, F. Garufi, Jhilik Majumdar, Salva Ardid, Christos Markou, C. Champion, Sergio Navas Concha, C. Pieterse, Mathieu Lamoureux, C. W. James, Ornella Leonardi, Marta Colomer Molla, E. Berbee, R. Bruijn, R. Wojaczyński, Andrey Romanov, Giuseppina Larosa, Riccardo Papaleo, Anvil Cruz, L. Maderer, G. Androulakis, R. Gracia, Mauro De Palma, V. Chiarella, H. M. Schutte, Jean-Paul Fransen, Uli Katz, Luigi Antonio Fusco, Jose Busto, T. Gal, C. Distefano, Manuel Doerr, D. F. E. Samtleben, A. Hekalo, Christophe Lerouvillois, M.C. Bouwhuis, P. Timmer, J. Schmelling, T. Thakore, Imad El Bojaddaini, J. Zúñiga, M. Bouta, A. Martini, Jannik Hofestaedt, Markus Boettcher, Mancia Anguita, Lukas Hennig, H. Hamdaoui, Annarita Margiotta, Louis-Marie Rigalleau, Aurelien Marini, D. Tézier, Alice Paun, Pasquale Migliozzi, Joern Wilms, Els de Wolf, Dídac Diego-Tortosa, A. W. Chen, Jerome Laurence, Antoine Kouchner, Walid Idrissi Ibnsalih, Barbara Caiffi, Daniel Lopez Coto, Alexander Enzenhoefer, A. Zegarelli, G. Pellegrini, Ofelia Pisanti, Oleg Kalekin, Fabio Pratolongo, Nafis Rezwan Khan-Chowdhury, Michel André, Philippe Lagier, Salvatore Viola, Sébastien Le Stum, Juan Garcia Mendez, Mitchell O'Sullivan, Michael Kreter, Antonio Ambrosone, M. Anghinolfi, Rémy Le Breton, Antonio Rapicavoli, Raffaele Buompane, Irene Sgura, Vladimir Kulikovskiy, G. Vasileiadis, Antonio F. Díaz, J. Manczak, D. Elsaesser, M. Ardid, Antonio Marinelli, E. Buis, Giuseppe Grella, C. Boutonnet, Juan Paris P. Gonzalez, Sebastiano Aiello, Thomas Lipreau, Isabella Probst, Nicole Geisselbrecht, S. Theraube, Km NeT, M. D. Filipovic, G.E. Păvălaş, Corinne Donzaud, Riccardo Bruno, Maitha Alshamsi, D. Stavropoulos, Vincent van Beveren, Veronique Van Elewyck, Abdelilah Moussa, B. O'Fearraigh, Paolo Musico, Francesca Tatone, Francisco Salesa Greus, Doriane Drouhin, G. Papalashvili, Frank Kayzel, Ahmed Eddyamoui, Bernardino Spisso, C. Guidi, Jerome Royon, Hervé Carduner, Matthias Kadler, Gisela Anton, Thijs van Eeden, Rosanna Cocimano, Paul de Jong, Marco Circella, Suzan Basegmez du Pree, Gilles Bouvet, Joao Coelho, E. Tenllado, Giulia Illuminati, M. Mongelli, L. Nauta, E. Tzamariudaki, D. Tzanetatos, Giorgi Kistauri, Peter Jansweijer, Cristiano Bozza, Victor Espinosa Rosello, Robert Lahmann, P. Coyle, C. Pastore, Paolo Castaldi, Lilian Martin, Giacomo Ottonello, Giacomo Cuttone, Carlos LLorens Alvarez, Rezo Shanidze, Matteo Sanguineti, Stavroula Tsagkli, Julien Aublin, Diego Real, Roberto Cereseto, Alberto Rovelli, Fabio Marzaioli, Antonio Capone, Maurizio Spurio, F. Huang, A.J. Heijboer, Arnauld Albert, Zineb Aly, M. Perrin-Terrin, J. Seneca, Carlo Alessandro Nicolau, Hassnae Eljarrari, William Assal, Massimiliano Lincetto, V. Bertin, Martin Friedrich Schneider, L. Caillat, Valentin Pestel, Miguel Gutiérrez, C. Poirè, Patrick Lamare, Daniele Zito, Hans van Haren, Irene Di Palma, S. M. Stellacci, Stefano Mastroianni, Marc Labalme, Agustin Sanchez Losa, Andrea Santangelo, Bruny Baret, M. Ageron, Stefano Campion, Damien Dornic, Jos Steijger, Alfonso Andres Garcia Soto, Julia Haefner, Miles Lindsey Clark, S. Beurthey, M. Bendahman, C. Bagatelas, M. Billault, P.M. Kooijman, J.J. Hernández-Rey, Silvio Cherubini, Paolo Fermani, J. Schumann, Francesco Leone, Sara Pulvirenti, Vasileios Tsourapis, Benoit Guillon, Yahya Tayalati, Jean Lesrel, Natalia Zywucka, Claudia Valieri, Federico Versari, and Alin Ilioni
Subjects: Physics, Dense array, Particle physics, KM3NeT, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Phase (waves), High Energy Physics::Experiment, Sensitivity (control systems), Neutrino, Neutrino oscillation
Abstract: KM3NeT/ORCA is a dense array that constitutes the low-energy branch of the KM3NeT project with the main goal of resolving the question of the neutrino mass ordering. At present, the KM3NeT/ORCA Phase 1 has already been deployed, which means that six out of the planned 115 detection lines are operational. Even with this limited configuration, neutrino oscillations can already be measured and studied. In this contribution, the sensitivity to the neutrino Non-Standard Interactions (NSI) parameter $\epsilon_{\mu \tau}$ using the current stage of the KM3NeT/ORCA detector together with the projections for the final configuration are presented.
Published: 2021

20. Development of an in-situ calibration device of firn properties for Askaryan neutrino detectors

Author: Manuel P. Paul, D. Z. Besson, Ilse Plaisier, Jiayi Liu, Shih-Hao Wang, Arianna, Stuart A. Kleinfelder, S. R. Klein, G. Gaswint, Steven W. Barwick, Robert Lahmann, Jiwoo Nam, Daniel García Fernández, Ryan Rice-Smith, Leshan Zhao, A. Anker, Mitchell Magnuson, C. Persichilli, Jordan C. Hanson, Lilly Pyras, Anna Nelles, Christoph Welling, Steffen Hallmann, N. Bingefors, Hans Bernhoﬀ, Pierre Baldi, Alexander Novikov, Stephen McAleer, Maddalena Cataldo, Jakob Beise, Zach Meyers, Christian Glaser, Allan Hallgren, Pisin Chen, and J. Tatar
Subjects: Physics, Neutrino detector, Firn, In situ calibration, Remote sensing
Published: 2021

21. Real-time Multi-Messenger Analysis Framework of KM3NeT

Author: Salva Ardid, Martin Friedrich Schneider, Louis-Marie Rigalleau, Richard Dallier, Bianca De Martino, Uli Katz, Imad El Bojaddaini, M. Bouta, L. Caillat, Nadja Lessing, Walid Idrissi Ibnsalih, Lukas Hennig, Annarita Margiotta, Thijs van Eeden, Paolo Fermani, Miguel Gutiérrez, Jutta Schnabel, Jean-Paul Fransen, S. Reck, Riccardo Bruno, T. Gal, C. Distefano, Manuel Doerr, Tommaso Chiarusi, P. Coyle, Giacomo Cuttone, Carlos LLorens Alvarez, A. Martini, S. Colonges, Jannik Hofestaedt, Daniele Vivolo, D. F. E. Samtleben, A. Hekalo, J. Seneca, C. Poirè, Maarten De Jong, Ad van den Berg, G. Vannoye, Michel André, Sara Pulvirenti, Soebur Razzaque, G. Papalashvili, Stefano Ottonello, Ahmed Eddyamoui, Matthias Bissinger, Hassnae Eljarrari, William Assal, Tarik Yousfi, Nick Lumb, A. Creusot, Daan van Eijk, Davit Janezashvili, M. Taiuti, Emmanuel Le Guirriec, Carlos Maximiliano Mollo, Massimiliano Lincetto, Frank Kayzel, D. Stavropoulos, Vincent van Beveren, Piera Sapienza, R. Muller, S. R. Gozzini, Bouke Jisse Jung, Bernardino Spisso, C. Guidi, Aurelien Marini, Giovanna Ferrara, Angelo Orlando, Isabella Probst, S. Theraube, V. Chiarella, P. Timmer, J. Schmelling, C. Champion, Vasileios Tsourapis, Stefano Campion, Damien Dornic, Jos Steijger, S. Beurthey, Maitha Alshamsi, Hans van Haren, Gennaro Miele, Gregory Lehaut, Irene Di Palma, Jhilik Majumdar, Veronique Van Elewyck, Abdelilah Moussa, Paolo Musico, Francesca Tatone, Doriane Drouhin, Thierry Pradier, Marco Circella, M. Mongelli, L. Nauta, J. Brunner, M. Bendahman, C. Bagatelas, Matteo Sanguineti, M. D. Filipovic, G.E. Păvălaş, Francisco Salesa Greus, Julia Haefner, Andrea Santangelo, Jose Busto, Miles Lindsey Clark, Rémy Le Breton, M. Billault, Silvia Celli, Massimiliano Cresta, V. Carretero, P.M. Kooijman, B. O'Fearraigh, Carmelo Pellegrino, F. Garufi, Benoit Guillon, Manuel Bou Cabo, Fabio Longhitano, R. Coniglione, Alba Domi, D. Calvo, Clara Gatius Oliver, Raffaele Buompane, Irene Sgura, Antonio F. Díaz, Hervé Carduner, Gisela Anton, Dídac Diego-Tortosa, Natalia Zywucka, Alfonso Andres Garcia Soto, Claudia Valieri, Luis Salvador Miranda Palacios, Bhuti Nkosi, Patrick Lamare, Daniele Zito, T. Thakore, J. Zúñiga, Evelyne Garcon, V. Popa, J.D. Zornoza, Ornella Leonardi, Marta Colomer Molla, E. Berbee, Federico Versari, Horea Branzas, Oleg Kalekin, Fabio Pratolongo, Juan Garcia Mendez, D. Gajanana, L. Maderer, H. M. Schutte, J.A. Martínez-Mora, Alexis Coleiro, Jean Lesrel, Thomas Eberl, Fabrizio Ameli, Nhan Chau, Mancia Anguita, Jihad Boumaaza, Steffen Hallmann, Nafis Rezwan Khan Chowdhury, E. Tzamariudaki, Emidio Giorgio, Daniel Lopez Coto, Yahya Tayalati, Giorgio Riccobene, Gilles Quemener, Philippe Lagier, Anvil Cruz, Km NeT, Christos Markou, S. Biagi, Lucio Gialanella, Nunzio Randazzo, Alessandro Lonardo, Giuseppe Levi, Corinne Donzaud, F. Filippini, Frits van der Knaap, C. Boutonnet, Steven Tingay, C. Pieterse, Mathieu Lamoureux, Juan Paris P. Gonzalez, Zineb Aly, Markus Boettcher, Michael Kreter, C. W. James, Domenico Santonocito, D. Guderian, M. Anghinolfi, M.C. Bouwhuis, R. Bruijn, Juan José Hernández-Rey, Antonio Rapicavoli, M. Perrin-Terrin, Piotr Kalaczyński, Alfonso Lazo, Antonio Marinelli, Kay Graf, Karel Melis, Alice Paun, Emanuele Leonora, R. Wojaczyński, Chiara Filomena Lastoria, Mohamed Chabab, R. Gracia, Carlo Alessandro Nicolau, A. Cosquer, Piotr Mijakowski, Christophe Lerouvillois, Sébastien Le Stum, Stavroula Tsagkli, Riccardo Papaleo, Antoine Kouchner, G. Vasileiadis, G. Androulakis, Ankur Sharma, Andrey Romanov, Julien Aublin, A. Zegarelli, Sergio Alves Garre, Emilio Migneco, Giuseppina Larosa, Mauro De Palma, Jerome Royon, Salvatore Viola, Matthias Kadler, Paul de Jong, Suzan Basegmez du Pree, Gilles Bouvet, Joao Coelho, E. Tenllado, Mitchell O'Sullivan, Luigi Antonio Fusco, Diego Real, Giulia Illuminati, A. W. Chen, Roberto Cereseto, Giacomo Ottonello, Fabio Marzaioli, Rezo Shanidze, Alberto Rovelli, S. M. Stellacci, Arnauld Albert, Stefano Mastroianni, Marc Labalme, P. Keller, Rosanna Cocimano, Antonio Capone, Pasquale Migliozzi, Joern Wilms, Peter Jansweijer, Maurizio Spurio, F. Huang, Victor Espinosa Rosello, A.J. Heijboer, C. Pastore, Antonio Ambrosone, Ofelia Pisanti, D. Tzanetatos, Giorgi Kistauri, Cristiano Bozza, Paolo Piattelli, A. Sinopoulou, Gerd Puehlhofer, M. Ardid, Sandra Zavatarelli, Nicole Geisselbrecht, H. Hamdaoui, Barbara Caiffi, G. Pellegrini, Francesco Benfenati, Hannes Thiersen, Gwenhaël de Wasseige, Mario Musumeci, S. Henry, A. D'Amico, Robert Lahmann, Paolo Castaldi, Lilian Martin, Valentin Pestel, Agustin Sanchez Losa, Alin Ilioni, Bruny Baret, M. Ageron, Silvio Cherubini, J. Schumann, Francesco Leone, Vladimir Kulikovskiy, J. Manczak, D. Elsaesser, E. Buis, Giuseppe Grella, Sebastiano Aiello, Thomas Lipreau, Els de Wolf, S. Sánchez Navas, Jerome Laurence, Alexander Enzenhoefer, D. Tézier, V. Bertin, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), École normale supérieure de Lyon (ENS de Lyon), KM3NeT, École normale supérieure - Lyon (ENS Lyon), Bianca Keilhauer, Alexander Kappes, Assal, W., Dornic, D., Huang, F., Le Guirriec, E., Lincetto, M., Vannoye, G., Ageron, M., Aiello, S., Albert, A., Alshamsi, M., Alves Garre, S., Aly, Z., Ambrosone, A., Ameli, F., Andre, M., Androulakis, G., Anghinolfi, M., Anguita, M., Anton, G., Ardid, M., Ardid, S., Aublin, J., Bagatelas, C., Baret, B., Basegmez du Pree, S., Bendahman, M., Benfenati, F., Berbee, E., van den Berg, A. M., Bertin, V., Beurthey, S., van Beveren, V., Biagi, S., Billault, M., Bissinger, M., Boettcher, M., Bou Cabo, M., Boumaaza, J., Bouta, M., Boutonnet, C., Bouvet, G., Bouwhuis, M., Bozza, C., Branzas, H., Bruijn, R., Brunner, J., Bruno, R., Buis, E., Buompane, R., Busto, J., Caiffi, B., Caillat, L., Calvo, D., Campion, S., Capone, A., Carduner, H., Carretero, V., Castaldi, P., Celli, S., Cereseto, R., Chabab, M., Champion, C., Chau, N., Chen, A., Cherubini, S., Chiarella, V., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Colomer Molla, M., Colonges, S., Coniglione, R., Cosquer, A., Coyle, P., Cresta, M., Creusot, A., Cruz, A., Cuttone, G., D'Amico, A., Dallier, R., De Martino, B., De Palma, M., Di Palma, I., Diaz, A. F., Diego-Tortosa, D., Distefano, C., Domi, A., Donzaud, C., Dorr, M., Drouhin, D., Eberl, T., Eddyamoui, A., van Eeden, T., van Eijk, D., El Bojaddaini, I., Eljarrari, H., Elsaesser, D., Enzenhofer, A., Espinosa, V., Fermani, P., Ferrara, G., Filipovic, M. D., Filippini, F., Fransen, J., Fusco, L. A., Gajanana, D., Gal, T., Garcia Mendez, J., Garcia Soto, A., Garcon, E., Garufi, F., Gatius, C., Geisselbrecht, N., Gialanella, L., Giorgio, E., Gozzini, S. R., Gracia, R., Graf, K., Grella, G., Guderian, D., Guidi, C., Guillon, B., Gutierrez, M., Haefner, J., Hallmann, S., Hamdaoui, H., van Haren, H., Heijboer, A., Hekalo, A., Hennig, L., Henry, S., Hernandez-Rey, J. J., Hofestadt, J., Idrissi Ibnsalih, W., Ilioni, A., Illuminati, G., James, C. W., Janezashvili, D., Jansweijer, P., de Jong, M., de Jong, P., Jung, B. J., Kadler, M., Kalaczynski, P., Kalekin, O., Katz, U. F., Kayzel, F., Keller, P., Khan Chowdhury, N. R., Kistauri, G., van der Knaap, F., Kooijman, P., Kouchner, A., Kreter, M., Kulikovskiy, V., Labalme, M., Lagier, P., Lahmann, R., Lamare, P., Lamoureux, M., Larosa, G., Lastoria, C., Laurence, J., Lazo, A., Le Breton, R., Le Stum, S., Lehaut, G., Leonardi, O., Leone, F., Leonora, E., Lerouvillois, C., Lesrel, J., Lessing, N., Levi, G., Lindsey Clark, M., Lipreau, T., LLorens Alvarez, C., Lonardo, A., Longhitano, F., Lopez-Coto, D., Lumb, N., Maderer, L., Majumdar, J., Manczak, J., Margiotta, A., Marinelli, A., Marini, A., Markou, C., Martin, L., Martinez-Mora, J. A., Martini, A., Marzaioli, F., Mastroianni, S., Melis, K. W., Miele, G., Migliozzi, P., Migneco, E., Mijakowski, P., Miranda, L. S., Mollo, C. M., Mongelli, M., Moussa, A., Muller, R., Musico, P., Musumeci, M., Nauta, L., Navas, S., Nicolau, C. A., Nkosi, B., Fearraigh, B. O., O'Sullivan, M., Orlando, A., Ottonello, G., Ottonello, S., Palacios Gonzalez, J., Papalashvili, G., Papaleo, R., Pastore, C., Paun, A. M., Pavalas, G. E., Pellegrini, G., Pellegrino, C., Perrin-Terrin, M., Pestel, V., Piattelli, P., Pieterse, C., Pisanti, O., Poire, C., Popa, V., Pradier, T., Pratolongo, F., Probst, I., Puhlhofer, G., Pulvirenti, S., Quemener, G., Randazzo, N., Rapicavoli, A., Razzaque, S., Real, D., Reck, S., Riccobene, G., Rigalleau, L., Romanov, A., Rovelli, A., Royon, J., Salesa Greus, F., Samtleben, D. F. E., Sanchez Losa, A., Sanguineti, M., Santangelo, A., Santonocito, D., Sapienza, P., Schmelling, J., Schnabel, J., Schneider, M. F., Schumann, J., Schutte, H. M., Seneca, J., Sgura, I., Shanidze, R., Sharma, A., Sinopoulou, A., Spisso, B., Spurio, M., Stavropoulos, D., Steijger, J., Stellacci, S. M., Taiuti, M., Tatone, F., Tayalati, Y., Tenllado, E., Tezier, D., Thakore, T., Theraube, S., Thiersen, H., Timmer, P., Tingay, S., Tsagkli, S., Tsourapis, V., Tzamariudaki, E., Tzanetatos, D., Valieri, C., Van Elewyck, V., Vasileiadis, G., Versari, F., Viola, S., Vivolo, D., de Wasseige, G., Wilms, J., Wojaczynski, R., de Wolf, E., Yousfi, T., Zavatarelli, S., Zegarelli, A., Zito, D., Zornoza, J. D., Zuniga, J., and Zywucka, N.
Subjects: data analysis method, accelerator, Computer science, Astrophysics::High Energy Astrophysical Phenomena, Real-time computing, FOS: Physical sciences, GeV, 01 natural sciences, 030218 nuclear medicine & medical imaging, High Energy Physics - Experiment, 03 medical and health sciences, High Energy Physics - Experiment (hep-ex), talk: online 2021/18/05, neutrino, 0302 clinical medicine, Observatory, 0103 physical sciences, supernova, optical, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], neutrino: supernova, 14. Life underwater, Neutrino oscillation, Instrumentation, KM3NeT, Mathematical Physics, Physics, 010308 nuclear & particles physics, Gravitational wave, Astrophysics::Instrumentation and Methods for Astrophysics, gravitational radiation, Astronomy, trigger, oscillation, observatory, monitoring, electromagnetic, neutrino: oscillation, proposed experiment, on-line
Abstract: KM3NeT is a multi-purpose cubic-kilometer neutrino observatory under construction in the Mediterranean Sea. It consists of ORCA and ARCA (for Oscillation and Astroparticle Research with Cosmics in the Abyss, respectively), currently both have a few detection lines in operation. Although having different primary goals, both detectors can be used for neutrino astronomy over a wide energy range, from a few tens of MeVs to a few tens of PeV. In view of the growing field of time-domain astronomy, it is crucial to be able to identify neutrino candidates in real-time. This online neutrino sample will allow triggered neutrino alerts that will be sent to the astronomy community and to look for time/space coincidences around external electromagnetic and multi-messenger triggers. These real-time searches can significantly increase the discovery potential of transient cosmic accelerators and refine the pointing directions in the case of poorly localized triggers, such as gravitational waves. In the field of core-collapse supernovae (CCSN), the detection of the MeV-scale CCSN neutrinos is crucial as an early warning of the electromagnetic follow-up. KM3NeT's digital optical modules act as good detectors for these supernovae neutrinos. This proceeding presents the status of KM3NeT's real-time multi-messenger activities, including online event reconstruction, event classification and selection, alert distribution, and supernova monitoring., 6 pages, 6 figures, VLVNT2021 conference proceedings
Published: 2021

22. Science case and detector concept for ARIANNA high energy neutrino telescope at Moore's Bay, Antarctica

Author: Zach Meyers, Arianna, Christian Glaser, Maddalena Cataldo, Steffen Hallmann, J. Tatar, A. Nelles, Hans Bernhoﬀ, Allan Hallgren, Jiayi Liu, Alexander Novikov, Stuart A. Kleinfelder, Pisin Chen, Jakob Beise, D. Z. Besson, Lilly Pyras, Leshan Zhao, Ilse Plaisier, Ryan Rice-Smith, Shih-Hao Wang, Daniel García Fernández, Mitchell Magnuson, Jordan C. Hanson, N. Bingefors, S. W. Barwick, Manuel P. Paul, Jiwoo Nam, Pierre Baldi, Steven W. Barwick, Stephen McAleer, G. Gaswint, Christoph Welling, A. Anker, C. Persichilli, Robert Lahmann, and S. R. Klein
Subjects: Physics, High energy, Detector, Neutrino telescope, Astronomy, Bay
Published: 2021

23. A novel trigger based on neural networks for radio neutrino detectors

Author: N. Bingefors, Hans Bernhoﬀ, Steven W. Barwick, Stephen McAleer, Shih-Hao Wang, Zach Meyers, Jakob Beise, Stuart A. Kleinfelder, Christian Glaser, Jiwoo Nam, Ryan Rice-Smith, G. Gaswint, Arianna, Alexander Novikov, Lilly Pyras, Anna Nelles, D. Z. Besson, Pierre Baldi, Ilse Plaisier, Maddalena Cataldo, A. Anker, C. Persichilli, Robert Lahmann, Christoph Welling, Leshan Zhao, Mitchell Magnuson, Jordan C. Hanson, Steffen Hallmann, J. Tatar, Allan Hallgren, Pisin Chen, S. R. Klein, Daniel García Fernández, Manuel P. Paul, and Jiayi Liu
Subjects: Physics, Artificial neural network, Neutrino detector, Electronic engineering
Published: 2021

24. Capabilities of ARIANNA: Neutrino Pointing Resolution and Implications for Future Ultra-high Energy Neutrino Astronomy

Author: Ilse Plaisier, Allan Hallgren, Pisin Chen, G. Gaswint, Hans Bernhoﬀ, Jakob Beise, Jiayi Liu, J. Tatar, Alexander Novikov, Jiwoo Nam, Stuart A. Kleinfelder, Ryan Rice-Smith, A. Nelles, Daniel García Fernández, Leshan Zhao, A. Anker, C. Persichilli, D. Z. Besson, Mitchell Magnuson, Jordan C. Hanson, Zach Meyers, Shih-Hao Wang, Christian Glaser, S. W. Barwick, Pierre Baldi, Stephen McAleer, Maddalena Cataldo, Christoph Welling, S. R. Klein, Robert Lahmann, Manuel P. Paul, Arianna, Lilly Pyras, N. Bingefors, Steffen Hallmann, and Steven W. Barwick
Subjects: Physics, Optics, Anechoic chamber, business.industry, Distortion, Detector, Angular resolution, Neutrino astronomy, Neutrino, business, Viewing angle, Polarization (waves)
Abstract: A radio-frequency polarization measurement by the ARIANNA surface station was performed using a residual hole from the South Pole Ice Core (SPICEcore) Project. Radio pulses were emitted from a transmitter located down to 1.7 km below the snow surface. After deconvolving the raw signals for the detector response and attenuation from propagation through the ice, the signal pulses show no significant distortion and agree with a reference measurement of the emitter made in an anechoic chamber. The direction to transmitted radio pulse was measured with an angular resolution of 0.37 degree [statistical error]. For polarization, the statistical error of the polarization vector is depth dependent and below 1 degree. In addition, a slow systematic error as a function of depth is 2.7 degrees. Neither the direction or polarization measurement show a significant offset as a function of depth relative to expectation. We also report on the results of a simulation study of the ARIANNA neutrino direction and energy resolution. The software tool NuRadioMC was used to reconstruct the polarization and viewing angle to determine the neutrino direction. Multiple models of Askaryan radiation and detector sites along with a range of neutrino energies were evaluated. The neutrino space angle resolution was determined to be below 3 degrees, which is comparable to the systematic polarization uncertainty. Therefore it is expected that the polarization resolution, which is the dominant contribution to the neutrino space angle resolution, will be improved in future studies by determining and eliminating systematic effects.
Published: 2021

25. Design and Sensitivity of the Radio Neutrino Observatory in Greenland (RNO-G)

Author: J. J. Beatty, Hans Bernhoff, Robert Lahmann, C. Hornhuber, Christian Glaser, Daniel P. Smith, Lilly Pyras, J. L. Kelley, Alexander Novikov, M. A. DuVernois, Brian Hendricks, Stijn Buitink, Cosmin Deaconu, Ilse Plaisier, Mitchell Magnuson, Albrecht Karle, Eric Oberla, K. D. de Vries, Steffen Hallmann, Paramita Dasgupta, Brian Clark, Adrian Zink, N. van Eijndhoven, H. Pandya, Dirk Ryckbosch, P. Allison, S. Toscano, Olga Botner, Daniel Southall, Abigail G. Vieregg, D. Van den Broeck, Jorge Torres, Zachary S. Meyers, C. Welling, Daniel García-Fernández, Katie Carter, Anna Nelles, Ryan Krebs, N. Bingefors, Olaf Scholten, A. Connolly, D. Seckel, S. De Kockere, Robert Young, N. Feigl, Allan Hallgren, J. C. Hanson, Stephanie Wissel, T. Meures, Kaeli Hughes, Bob Oeyen, Ben Hokanson-Fasig, David Zeke Besson, Juanan Aguilar, Spencer Klein, Physics, Elementary Particle Physics, and Faculty of Sciences and Bioengineering Sciences
Subjects: Physics::Instrumentation and Detectors, Astrophysics::High Energy Astrophysical Phenomena, ice, FOS: Physical sciences, 7. Clean energy, 01 natural sciences, 030218 nuclear medicine & medical imaging, Askaryan effect, 03 medical and health sciences, neutrino, 0302 clinical medicine, Observatory, 0103 physical sciences, hardware, Neutrino detectors, 14. Life underwater, Sensitivity (control systems), ddc:610, Instrumentation, Instrumentation and Methods for Astrophysics (astro-ph.IM), Mathematical Physics, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), astro-ph.HE, Large detector systems for particle and astroparticle physics, 010308 nuclear & particles physics, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Astronomy, sensitivity, cascade, observatory, detector [radio wave], Physics and Astronomy, Neutrino detector, Physique des particules élémentaires, High Energy Physics::Experiment, Neutrino, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, astro-ph.IM
Abstract: This article presents the design of the Radio Neutrino Observatory Greenland (RNO-G) and discusses its scientific prospects. Using an array of radio sensors, RNO-G seeks to measure neutrinos above 10 PeV by exploiting the Askaryan effect in neutrino-induced cascades in ice. We discuss the experimental considerations that drive the design of RNO-G, present first measurements of the hardware that is to be deployed and discuss the projected sensitivity of the instrument. RNO-G will be the first production-scale radio detector for in-ice neutrino signals., Comment: 51 pages, 27 figures, version updated to include corrected figure of effective areas
Published: 2021

26. Architecture and performance of the KM3NeT front-end firmware

Author: Suzan Basegmez du Pree, Daan van Eijk, Silvia Celli, Francisco Salesa Greus, Fabrizio Raffaelli, Joao Coelho, E. Tenllado, M. Taiuti, Carlos Maximiliano Mollo, S. Mazzou, Gisela Anton, Diego Real, S. Biagi, Antonio D'Onofrio, Giulia Illuminati, Alessandro Lonardo, E. Tzamariudaki, Alfonso Andres Garcia Soto, Uli Katz, Thijs van Eeden, David Muñoz Pérez, M. Morganti, Jörn Wilms, Thierry Pradier, S. Rivoire, P. Coyle, Imad El Bojaddaini, Zineb Aly, Giacomo Cuttone, M. Perrin-Terrin, Carlo Alessandro Nicolau, H. Brânzaş, Thomas Eberl, Dídac Diego-Tortosa, M. Bouta, K. Pikounis, Paolo Fermani, Gwenhaël de Wasseige, Mario Musumeci, D. Stavropoulos, Vincent van Beveren, S. Colonges, Veronique Van Elewyck, Abdelilah Moussa, Paolo Musico, Tommaso Chiarusi, Miles Lindsey Clark, P.M. Kooijman, R. Muller, S. M. Stellacci, Emanuele Leonora, S. R. Gozzini, M. Ardid, Jose Busto, Bouke Jisse Jung, Michael Kreter, M. Anghinolfi, A. Martini, N. Geißelbrecht, Annarita Margiotta, A. D'Amico, Dario Grasso, T. Thakore, Sara Pulvirenti, Jean Lesrel, Stefano Mastroianni, A. W. Chen, Doriane Drouhin, H. Hamdaoui, Mohamed Chabab, Jutta Schnabel, Giovanna Ferrara, J.J. Hernández-Rey, Jürgen Brunner, Rémy Le Breton, Raffaele Buompane, Damien Dornic, Angelo Orlando, Jos Steijger, Rosanna Cocimano, Irene Sgura, Antonio F. Díaz, Andrea Biagioni, S. Reck, Corinne Donzaud, Barbara Caiffi, Piotr Mijakowski, G. Pellegrini, Michel André, Alin Ilioni, Francesco Simeone, Fabio Marzaioli, Giancarlo Barbarino, M. Richer, Paolo Piattelli, A. Sinopoulou, M. Bendahman, C. Bagatelas, Sandra Zavatarelli, Juan Paris P. Gonzalez, R. Wojaczyński, R. Bruijn, Arnauld Albert, Riccardo Papaleo, Julien Aublin, M. Dörr, G. Androulakis, R. Coniglione, T. Gal, R. Gracia, C. Distefano, Antoine Kouchner, Ofelia Pisanti, Richard Dallier, Daniele Vivolo, D. F. E. Samtleben, A. Hekalo, Mancia Anguita, Matthias Bissinger, A. Zegarelli, Robert Lahmann, J. Hofestädt, Paolo Castaldi, Lilian Martin, Bernardino Spisso, C. Guidi, Pasquale Migliozzi, Jihad Boumaaza, Mitchell O'Sullivan, L. Maderer, R. Donà, Y. Gatelet, Natalia Zywucka, O. Rabyang, Agustin Sanchez Losa, Els Koffeman, Federico Versari, A. Belias, Bruny Baret, Markus Boettcher, Rezo Shanidze, Silvio Cherubini, J. Schumann, Francesco Leone, D. Guderian, D. Tzanetatos, Giorgi Kistauri, Cristiano Bozza, Kay Graf, Karel Melis, Walid Idrissi Ibnsalih, Soebur Razzaque, Piera Sapienza, V. Chiarella, J. Schmelling, G. Pühlhofer, Fabio Longhitano, V. Carretero, Nhan Chau, Piotr Kalaczyński, Giuseppina Larosa, Mauro De Palma, G. Papalashvili, Karl Mannheim, D. Zaborov, Marco Circella, Ahmed Eddyamoui, L. Nauta, Victor Espinosa Rosell, Matteo Sanguineti, Christos Markou, Carmelo Pellegrino, F. Garufi, C. Pieterse, V. Bertin, C. W. James, Alice Paun, M. D. Filipovic, G.E. Păvălaş, C. Poirè, G. Vasileiadis, Daniele Zito, S. Viola, Ankur Sharma, Ornella Leonardi, Maarten De Jong, Marta Colomer Molla, E. Berbee, Sergio Alves Garre, Emilio Migneco, Imanol Corredoira, Ad van den Berg, Nafis Rezwan Khan Chowdhury, Oleg Kalekin, M. Organokov, B. Ó Fearraigh, A. Creusot, Antonio Marinelli, Gennaro Miele, Giorgio Riccobene, Lucio Gialanella, J.D. Zornoza, Nunzio Randazzo, Giuseppe Levi, F. Filippini, Frits van der Knaap, Steven Tingay, Domenico Santonocito, J. Seneca, Michael Moser, Alba Domi, D. Calvo, Massimiliano Lincetto, D. Lopez-Coto, V. Popa, Steffen Hallmann, Hans van Haren, Irene Di Palma, Andrea Santangelo, Yahya Tayalati, Matthias Kadler, Paul de Jong, Peter Jansweijer, C. Pastore, Luis Salvador Miranda Palacios, J. Zúñiga, J.A. Martínez-Mora, Alexis Coleiro, Fabrizio Ameli, Alberto Rovelli, Emidio Giorgio, Vladimir Kulikovskiy, Luigi Antonio Fusco, Antonio Capone, J. Manczak, D. Elsaesser, Maurizio Spurio, E. Buis, F. Huang, A.J. Heijboer, M.C. Bouwhuis, Giuseppe Grella, Sebastiano Aiello, Thomas Lipreau, Els de Wolf, S. Sánchez Navas, Alexander Enzenhoefer, O. Gabella, KM3NeT (IHEF, IoP, FNWI), Aiello, Sebastiano, Albert, Arnauld, Garre, Sergio Alve, Aly, Zineb, Ameli, Fabrizio, Andre, Michel, Androulakis, Giorgo, Anghinolfi, Marco, Anguita, Mancia, Anton, Gisela, Ardid, Miquel, Aublin, Julien, Bagatelas, Christo, Barbarino, Giancarlo, Baret, Bruny, Basegmez du Pree, Suzan, Belias, Anastasio, Bendahman, Meriem, Berbee, Edward, van den Berg, Ad M., Bertin, Vincent, van Beveren, Vincent, Biagi, Simone, Biagioni, Andrea, Bissinger, Matthia, Boettcher, Marku, Boumaaza, Jihad, Bouta, Mohammed, Bouwhuis, Mieke, Bozza, Cristiano, Brânzaş, Horea, Bruijn, Ronald, Brunner, Jurgen, Buis, Ernst-Jan, Buompane, Raffaele, Busto, Jose, Caiffi, Barbara, Calvo, David, Capone, Antonio, Carretero, Victor, Castaldi, Paolo, Celli, Silvia, Chabab, Mohamed, Chau, Nhan, Chen, Andrew W., Cherubini, Silvio, Chiarella, Vitaliano, Chiarusi, Tommaso, Circella, Marco, Cocimano, Rosanna, Coelho, Joao A. B., Coleiro, Alexi, Molla, Marta C., Colonges, Stephane, Coniglione, Rosa, Corredoira, Imanol, Coyle, Paschal, Creusot, Alexandre, Cuttone, Giacomo, Amico, Antonio D’, D’Onofrio, Antonio, Dallier, Richard, De Palma, Mauro, Di Palma, Irene, Díaz, Antonio F., Diego-Tortosa, Didac, Distefano, Carla, Domi, Alba, Donà, Roberto, Donzaud, Corinne, Dornic, Damien, Dörr, Manuel, Drouhin, Doriane, Eberl, Thoma, Eddyamoui, Ahmed, van Eeden, Thij, van Eijk, Daan, El Bojaddaini, Imad, Elsaesser, Dominik, Enzenhoefer, Alexander, Rosell, Victor Espinosa, Fermani, Paolo, Ferrara, Giovanna, Filipović, Miroslav D., Filippini, Francesco, Fusco, Luigi A., Gabella, Omar, Gal, Tama, Soto, Alfonso Andres Garcia, Garufi, Fabio, Gatelet, Yoann, Geißelbrecht, Nicole, Gialanella, Lucio, Giorgio, Emidio, Gozzini, Sara R., Gracia, Rodrigo, Graf, Kay, Grasso, Dario, Grella, Giuseppe, Guderian, Daniel, Guidi, Carlo, Hallmann, Steffen, Hamdaoui, Hassane, van Haren, Han, Heijboer, Aart, Hekalo, Amar, Hernández-Rey, Juan J., Hofestädt, Jannik, Huang, Feifei, Ibnsalih, Walid Idrissi, Ilioni, Alin, Illuminati, Giulia, James, Clancy W., Jansweijer, Peter, de Jong, Maartin, de Jong, Paul, Jung, Bouke Jisse, Kadler, Matthia, Kalaczyński, Piotr, Kalekin, Oleg, Katz, Uli F., Khan Chowdhury, Nafis R., Kistauri, Giorgi, van der Knaap, Frit, Koffeman, Els N., Kooijman, Paul, Kouchner, Antoine, Kreter, Michael, Kulikovskiy, Vladimir, Lahmann, Robert, Larosa, Giuseppina, Le Breton, Remy, Leonardi, Ornella, Leone, Francesco, Leonora, Emanuele, Lesrel, Jean, Levi, Giuseppe, Lincetto, Massimiliano, Lindsey Clark, Mile, Lipreau, Thoma, Lonardo, Alessandro, Longhitano, Fabio, Lopez-Coto, Daniel, Maderer, Luka, Mańczak, Jerzy M., Mannheim, Karl, Margiotta, Annarita, Marinelli, Antonio, Markou, Christo, Martin, Lilian, Martínez-Mora, Juan A., Martini, Agnese, Marzaioli, Fabio, Mastroianni, Stefano, Mazzou, Safaa, Melis, Karel W., Miele, Gennaro, Migliozzi, Pasquale, Migneco, Emilio, Mijakowski, Piotr, Miranda Palacios, Luis S., Mollo, Carlos M., Morganti, Mauro, Moser, Michael, Moussa, Abdelilah, Muller, Rasa, Pérez, David Muñoz, Musico, Paolo, Musumeci, Mario, Nauta, Lodewijk, Navas, Sergio, Nicolau, Carlo A., Fearraigh, Brian Ó., O’Sullivan, Mitchell, Organokov, Mukharbek, Orlando, Angelo, González, Juan Palacio, Papalashvili, Gogita, Papaleo, Riccardo, Pastore, Cosimo, Păun, Alice M., Păvălaş, Gabriela E., Pellegrini, Giuliano, Pellegrino, Carmelo, Perrin-Terrin, Mathieu, Piattelli, Paolo, Pieterse, Camiel, Pikounis, Konstantino, Pisanti, Ofelia, Poirè, Chiara, Popa, Vlad, Pradier, Thierry, Pühlhofer, Gerd, Pulvirenti, Sara, Rabyang, Omphile, Raffaelli, Fabrizio, Randazzo, Nunzio, Razzaque, Soebur, Real, Diego, Reck, Stefan, Riccobene, Giorgio, Richer, Marc, Rivoire, Stephane, Rovelli, Alberto, Salesa Greus, Francisco, Samtleben, Dorothea F. E., Sánchez Losa, Agustin, Sanguineti, Matteo, Santangelo, Andrea E., Santonocito, Domenico, Sapienza, Piera, Schmelling, Jan-Willem, Schnabel, Jutta, Schumann, Johanne, Seneca, Jordan, Sgura, Irene, Shanidze, Rezo, Sharma, Ankur, Simeone, Francesco, Sinopoulou, Anna, Spisso, Bernardino, Spurio, Maurizio, Stavropoulos, Dimitri, Steijger, Jo, Stellacci, Simona Maria, Taiuti, Mauro, Tayalati, Yahya, Tenllado, Enrique, Thakore, Tarak, Tingay, Steven, Tzamariudaki, Ekaterini, Tzanetatos, Dimitrio, Van Elewyck, Veronique, Vasileiadis, George, Versari, Federico, Viola, Salvo, Vivolo, Daniele, de Wasseige, Gwenhael, Wilms, Joern, Wojaczyński, Rafa, de Wolf, El, Zaborov, Dmitry, Zavatarelli, Sandra, Zegarelli, Angela, Zito, Daniele, de Dios Zornoza, Juan, Zúñiga, Juan, Zywucka, Natalia, Aiello, S., Albert, A., Garre, S. A., Aly, Z., Ameli, F., Andre, M., Androulakis, G., Anghinolfi, M., Anguita, M., Anton, G., Ardid, M., Aublin, J., Bagatelas, C., Barbarino, G., Baret, B., Du Pree, S. B., Belias, A., Bendahman, M., Berbee, E., Van Den Berg, A. M., Bertin, V., Van Beveren, V., Biagi, S., Biagioni, A., Bissinger, M., Boettcher, M., Boumaaza, J., Bouta, M., Bouwhuis, M., Bozza, C., Branzas, H., Bruijn, R., Brunner, J., Buis, E. -J., Buompane, R., Busto, J., Caiffi, B., Calvo, D., Capone, A., Carretero, V., Castaldi, P., Celli, S., Chabab, M., Chau, N., Chen, A., Cherubini, S., Chiarella, V., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Molla, M. C., Colonges, S., Coniglione, R., Corredoira, I., Coyle, P., Creusot, A., Cuttone, G., Amico, A. D., D'Onofrio, A., Dallier, R., De Palma, M., Di Palma, I., Diaz, A. F., Diego-Tortosa, D., Distefano, C., Domi, A., Dona, R., Donzaud, C., Dornic, D., Doerr, M., Drouhin, D., Eberl, T., Eddyamoui, A., Van Eeden, T., Van Eijk, D., El Bojaddaini, I., Elsaesser, D., Enzenhoefer, A., Rosell, V. E., Fermani, P., Ferrara, G., Filipovic, M. D., Filippini, F., Fusco, L. A., Gabella, O., Gal, T., Soto, A. A. G., Garufi, F., Gatelet, Y., Geisselbrecht, N., Gialanella, L., Giorgio, E., Gozzini, S. R., Gracia, R., Graf, K., Grasso, D., Grella, G., Guderian, D., Guidi, C., Hallmann, S., Hamdaoui, H., Van Haren, H., Heijboer, A., Hekalo, A., Hernandez-Rey, J. J., Hofestadt, J., Huang, F., Ibnsalih, W. I., Ilioni, A., Illuminati, G., James, C. W., Jansweijer, P., De Jong, M., De Jong, P., Jung, B. J., Kadler, M., Kalaczynski, P., Kalekin, O., Katz, U. F., Chowdhury, N. R. K., Kistauri, G., Van Der Knaap, F., Koffeman, E. N., Kooijman, P., Kouchner, A., Kreter, M., Kulikovskiy, V., Lahmann, R., Larosa, G., Le Breton, R., Leonardi, O., Leone, F., Leonora, E., Lesrel, J., Levi, G., Lincetto, M., Clark, M. L., Lipreau, T., Lonardo, A., Longhitano, F., Lopez-Coto, D., Maderer, L., Manczak, J. M., Mannheim, K., Margiotta, A., Marinelli, A., Markou, C., Martin, L., Martinez-Mora, J. A., Martini, A., Marzaioli, F., Mastroianni, S., Mazzou, S., Melis, K. W., Miele, G., Migliozzi, P., Migneco, E., Mijakowski, P., Palacios, L. S. M., Maximiliano Mollo, C., Morganti, M., Moser, M., Moussa, A., Muller, R., Perez, D. M., Musico, P., Musumeci, M., Nauta, L., Navas, S., Nicolau, C. A., Fearraigh, B. O., O'Sullivan, M., Organokov, M., Orlando, A., Gonzalez, J. P., Papalashvili, G., Papaleo, R., Pastore, C., Paun, A. M., Pavalas, G. E., Pellegrini, G., Pellegrino, C., Perrin-Terrin, M., Piattelli, P., Pieterse, C., Pikounis, K., Pisanti, O., Poire, C., Popa, V., Pradier, T., Puhlhofer, G., Pulvirenti, S., Rabyang, O., Raffaelli, F., Randazzo, N., Razzaque, S., Real, D., Reck, S., Riccobene, G., Richer, M., Rivoire, S., Rovelli, A., Salesa Greus, F., Samtleben, D. F. E., Losa, A. S., Sanguineti, M., Santangelo, A. E., Santonocito, D., Sapienza, P., Schmelling, J. -W., Schnabel, J., Schumann, J., Seneca, J., Sgura, I., Shanidze, R., Sharma, A., Simeone, F., Sinopoulou, A., Spisso, B., Spurio, M., Stavropoulos, D., Steijger, J., Stellacci, S. M., Taiuti, M., Tayalati, Y., Tenllado, E., Thakore, T., Tingay, S., Tzamariudaki, E., Tzanetatos, D., Van Elewyck, V., Vasileiadis, G., Versari, F., Viola, S., Vivolo, D., De Wasseige, G., Wilms, J., Wojaczynski, R., De Wolf, E., Zaborov, D., Zavatarelli, S., Zegarelli, A., Zito, D., De Dios Zornoza, J., Zuniga, J., Zywucka, N., Groupe de Recherche en Physique des Hautes Energies (GRPHE), Institut Universitaire de Technologie de Colmar-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Laboratoire de physique subatomique et des technologies associées (SUBATECH), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Laboratoire Univers et Particules de Montpellier (LUPM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Montpellier 2 - Sciences et Techniques (UM2), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), KM3NeT, Research unit Astroparticle Physics, Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-IUT de Colmar, Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique et Atmosphères = Laboratory for Studies of Radiation and Matter in Astrophysics and Atmospheres (LERMA), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-CY Cergy Paris Université (CY), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), ANR-15-CE31-0020,DAEMONS,Démonstration de la possibilité d'établir l'ordonnancement des masses de neutrinos dans la mer(2015), ANR-10-LABX-0023,UnivEarthS,Earth - Planets - Universe: observation, modeling, transfer(2010), ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018), Centre Tecnològic de Vilanova i la Geltrú, and Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques
Subjects: Astrofísica, acquisition firmware, KM3NeT, neutrino telescope, time to digital converters, Computer science, data acquisition, Physics::Instrumentation and Detectors, time-to-digital converter, computer.software_genre, Astrophysics, Neutrino telescope, 01 natural sciences, Front and back ends, Time-to-digital converter, Atmospheric Cherenkov telescopes, time to digital converter, 010303 astronomy & astrophysics, Instrumentation, FPGA, Clocks, photomultiplier, Firmware, 4. Education, Physics, Electrical engineering, Astrophysics::Instrumentation and Methods for Astrophysics, Electronic, Optical and Magnetic Materials, Acquisition firmware, Neutrino, performance, Photomultiplier, Logic, Astrophysics::High Energy Astrophysical Phenomena, Physique [physics]/Physique [physics], Partícules (Física nuclear), 010309 optics, 0103 physical sciences, Quantization, 14. Life underwater, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Field-programmable gate array, Cherenkov radiation, Particles (Nuclear physics), Detectors òptics, Time to digital converters, Optical detectors, Control systems, Photons, Física [Àrees temàtiques de la UPC], Telescopis, business.industry, Mechanical Engineering, Data acquisition, Field programmable gate arrays, Astronomy and Astrophysics, Physique [physics]/Physique des Hautes Energies - Expérience [hep-ex], Space and Planetary Science, Control and Systems Engineering, FISICA APLICADA, electronics: readout, business, computer, Telescopes, electronics: design
Abstract: The authors acknowledge the financial support of the funding agencies: Agence Nationale de la Recherche (contract ANR-15-CE31-0020), Centre National de la Recherche Scientifique (CNRS), Commission Europeenne (FEDER fund and Marie Curie Program), Institut Universitaire de France (IUF), LabEx UnivEarthS (ANR-10-LABX-0023 and ANR-18-IDEX-0001), Paris Ile-de-France Region, France; Shota Rustaveli National Science Foundation of Georgia (SRNSFG, FR-18-1268), Georgia; Deutsche Forschungsgemeinschaft (DFG), Germany; The General Secretariat of Research and Technology (GSRT), Greece; Istituto Nazionale di Fisica Nucleare (INFN), Ministero dell'Istruzione, dell'Universita e della Ricerca (MIUR), PRIN 2017 program (Grant NAT-NET 2017W4HA7S) Italy; Ministry of Higher Education Scientific Research and Professional Training, ICTP through Grant AF-13, Morocco; Nederlandse organisatie voor Wetenschappelijk Onderzoek (NWO), the Netherlands; The National Science Centre, Poland (2015/18/E/ST2/00758); National Authority for Scientific Research (ANCS), Romania; Ministerio de Ciencia, Innovacion, Investigacion y Universidades (MCIU): Programa Estatal de Generacion de Conocimiento (refs. PGC2018-096663-B-C41, -A-C42, -B-C43, -B-C44) (MCIU/FEDER), Severo Ochoa Centre of Excellence and MultiDark Consolider (MCIU), Junta de Andalucia (ref. SOMM17/6104/UGR), Generalitat Valenciana: Grisolia (ref. GRISOLIA/2018/119) and GenT (ref. CIDEGENT/2018/034) programs, La Caixa Foundation (ref. LCF/BQ/IN17/11620019), EU: MSC program (ref. 713673), Spain., The KM3NeT infrastructure consists of two deep-sea neutrino telescopes being deployed in the Mediterranean Sea. The telescopes will detect extraterrestrial and atmospheric neutrinos by means of the incident photons induced by the passage of relativistic charged particles through the seawater as a consequence of a neutrino interaction. The telescopes are configured in a three-dimensional grid of digital optical modules, each hosting 31 photomultipliers. The photomultiplier signals produced by the incident Cherenkov photons are converted into digital information consisting of the integrated pulse duration and the time at which it surpasses a chosen threshold. The digitization is done by means of time to digital converters (TDCs) embedded in the field programmable gate array of the central logic board. Subsequently, a state machine formats the acquired data for its transmission to shore. We present the architecture and performance of the front-end firmware consisting of the TDCs and the state machine., French National Research Agency (ANR) ANR-15-CE31-0020, Centre National de la Recherche Scientifique (CNRS), Commission Europeenne (FEDER fund), France, Commission Europeenne (Marie Curie Program), France, Institut Universitaire de France (IUF), France, LabEx UnivEarthS, France ANR-10-LABX-0023 ANR-18-IDEX-0001, Paris Ile-de-France Region, France, Shota Rustaveli National Science Foundation of Georgia (SRNSFG), Georgia FR-18-1268, German Research Foundation (DFG), Greek Ministry of Development-GSRT, Istituto Nazionale di Fisica Nucleare (INFN) NAT-NET 2017W4HA7S, Ministry of Education, Universities and Research (MIUR) NAT-NET 2017W4HA7S, PRIN 2017 program Italy NAT-NET 2017W4HA7S, Ministry of Higher Education Scientific Research and Professional Training, ICTP, Morocco AF-13, Netherlands Organization for Scientific Research (NWO) Netherlands Government, National Science Centre, Poland 2015/18/E/ST2/00758, National Authority for Scientific Research (ANCS), Romania, Ministerio de Ciencia, Innovacion, Investigacion y Universidades (MCIU): Programa Estatal de Generacion de Conocimiento (MCIU/FEDER), Spain PGC2018-096663-B-C41 PGC2018-096663-A-C42 PGC2018-096663-B-C43 PGC2018-096663-B-C44, Severo Ochoa Centre of Excellence and MultiDark Consolider (MCIU), Spain, Junta de Andalucia European Commission SOMM17/6104/UGR, Generalitat Valenciana: Grisolia program, Spain GRISOLIA/2018/119, Generalitat Valenciana: GenT program, Spain CIDEGENT/2018/034, La Caixa Foundation LCF/BQ/IN17/11620019, EU: MSC program, Spain 713673
Published: 2021

27. Measurement of the atmospheric νe and νμ energy spectra with the ANTARES neutrino telescope

Author: A. Marinelli, R. Cherkaoui El Moursli, Alba Domi, Julien Aublin, G. Illuminati, Jose Busto, M. Perrin-Terrin, M.C. Bouwhuis, T. Thakore, J. Zúñiga, D. Lopez-Coto, M. Ardid, V. Popa, I. Kreykenbohm, Steffen Hallmann, Vladimir Kulikovskiy, M. Circella, J. Manczak, Matthias Kadler, F. Salesa Greus, Paolo Sapienza, Alessia Capone, J. Brunner, A. Creusot, C. Pellegrino, V. Carretero, Tommaso Chiarusi, S. Sánchez Navas, A. Enzenhöfer, H. Brânzaş, M. Bouta, Arnauld Albert, N.R. Khan-Chowdhury, T. N. Chau, Maurizio Spurio, Emanuele Leonora, J-J. Aubert, Dominique Lefèvre, N. Randazzo, F. Huang, B. Baret, C. Guidi, F. Versari, J. Carr, A.J. Heijboer, Mohamed Chabab, Damien Dornic, Annarita Margiotta, C. Pieterse, O. Kalekin, Giuseppe Levi, J.A. Martínez-Mora, Alexis Coleiro, F. Filippini, A. Sánchez-Losa, Steven Tingay, C. W. James, J.J. Hernández-Rey, Yahya Tayalati, Michel André, C. Donzaud, R. Coniglione, F. Schüssler, Kay Graf, Daniele Vivolo, Karel Melis, J. Hößl, S. Basa, Michael Moser, P. Coyle, Massimiliano Lincetto, D. Drouhin, Gisela Anton, M. Bendahman, B. Vallage, M. Colomer-Molla, Hervé Glotin, V. Van Elewyck, J.D. Zornoza, M. de Jong, J. Hofestädt, Jihad Boumaaza, S. Alves, Jutta Schnabel, Joern Wilms, S. Reck, M. Marcelin, M. Jongen, C. Distefano, D. F. E. Samtleben, Paolo Fermani, L. Caramete, Giovanna Ferrara, L. Fusco, M. Taiuti, Yann Hello, H. van Haren, B. Jisse-Jung, Th. Stolarczyk, S. Loucatos, S.F. Biagi, Thierry Pradier, B. Belhorma, R. Gozzini, U. Katz, M. Anghinolfi, N. El Khayati, I. Di Palma, Antonio F. Díaz, Antoine Kouchner, A. Zegarelli, A. Nuñez-Castiñeyra, P. de Jong, Abdelilah Moussa, L. Maderer, Anne Deschamps, L. Nauta, Matteo Sanguineti, G. Riccobene, V. Bertin, E. Nezri, R. Bruijn, R. Muller, J. Schumann, G. de Wasseige, Silvia Celli, Thomas Eberl, M. Bissinger, C. Poirè, P. Piattelli, Robert Lahmann, R. Le Breton, S. Viola, M. Organokov, R. García, G.E. Păvălaş, B. O'Fearraigh, Y. Gatelet, P. Migliozzi, Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Géoazur (GEOAZUR 7329), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Université Paris-Sud - Paris 11 (UP11), Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Laboratoire d'Informatique et Systèmes (LIS), Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Institut méditerranéen d'océanologie (MIO), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), ANTARES, ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, KM3NeT (IHEF, IoP, FNWI), ATLAS (IHEF, IoP, FNWI), IHEF (IoP, FNWI), Albert A., Alves S., Andre M., Anghinolfi M., Anton G., Ardid M., Aubert J.-J., Aublin J., Baret B., Basa S., Belhorma B., Bendahman M., Bertin V., Biagi S., Bissinger M., Boumaaza J., Bouta M., Bouwhuis M.C., Branzas H., Bruijn R., Brunner J., Busto J., Capone A., Caramete L., Carr J., Carretero V., Celli S., Chabab M., Chau T.N., Cherkaoui El Moursli R., Chiarusi T., Circella M., Coleiro A., Colomer-Molla M., Coniglione R., Coyle P., Creusot A., Diaz A.F., de Wasseige G., Deschamps A., Distefano C., Di Palma I., Domi A., Donzaud C., Dornic D., Drouhin D., Eberl T., El Khayati N., Enzenhofer A., Fermani P., Ferrara G., Filippini F., Fusco L., Garcia R., Gatelet Y., Gay P., Glotin H., Gozzini R., Graf K., Guidi C., Hallmann S., van Haren H., Heijboer A.J., Hello Y., Hernandez-Rey J.J., Hossl J., Hofestadt J., Huang F., Illuminati G., James C.W., Jisse-Jung B., de Jong M., de Jong P., Jongen M., Kadler M., Kalekin O., Katz U., Khan-Chowdhury N.R., Kouchner A., Kreykenbohm I., Kulikovskiy V., Lahmann R., Le Breton R., Lefevre D., Leonora E., Levi G., Lincetto M., Lopez-Coto D., Loucatos S., Maderer L., Manczak J., Marcelin M., Margiotta A., Marinelli A., Martinez-Mora J.A., Melis K., Migliozzi P., Moser M., Moussa A., Muller R., Nauta L., Navas S., Nezri E., Nunez-Castineyra A., O'Fearraigh B., Organokov M., Pavalas G.E., Pellegrino C., Perrin-Terrin M., Piattelli P., Pieterse C., Poire C., Popa V., Pradier T., Randazzo N., Reck S., Riccobene G., Salesa Greus F., Samtleben D.F.E., Sanchez-Losa A., Sanguineti M., Sapienza P., Schnabel J., Schumann J., Schussler F., Spurio M., Stolarczyk T., Taiuti M., Tayalati Y., Thakore T., Tingay S.J., Vallage B., Van Elewyck V., Versari F., Viola S., Vivolo D., Wilms J., Zegarelli A., Zornoza J.D., and Zuniga J.
Subjects: electron, neutrino/e: energy spectrum, Physics::Instrumentation and Detectors, ice, Atmospheric neutrino, KAMIOKANDE, Electron, GeV, Neutrino telescope, 7. Clean energy, 01 natural sciences, charged current, High Energy Physics - Experiment, ANTARES, Atmospheric neutrinos, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], neutrino/e: particle identification, Muon neutrino, neutrino: interaction, Charged current, Physics, Range (particle radiation), 4. Education, suppression, lcsh:QC1-999, muon: atmosphere, neutrino/e: flux, neutrino: detector, Neutrino detector, Neutrino, Astrophysics - High Energy Astrophysical Phenomena, data analysis method, Nuclear and High Energy Physics, neutral current, Astrophysics::High Energy Astrophysical Phenomena, energy spectrum, neutrino/mu: flux, Nuclear physics, 0103 physical sciences, TeV, Neutrinos, 010306 general physics, Detectors òptics, Optical detectors, neutrino/mu: particle identification, Muon, Telescopis, neutrino/mu: energy spectrum, Neutral current, background, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, tracks, Atmosfera, 13. Climate action, Física::Astronomia i astrofísica [Àrees temàtiques de la UPC], FISICA APLICADA, High Energy Physics::Experiment, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], lcsh:Physics, Telescopes, experimental results
Abstract: The authors acknowledge the financial support of the funding agencies: Centre National de la Recherche Scientifique (CNRS), Commissariat a l'Energie Atomique et aux Energies Alternatives(CEA), Commission Europeenne (FEDER fund and Marie Curie Program), Institut Universitaire de France (IUF), Labex UnivEarthS(ANR-10-LABX-0023 and ANR-18-IDEX-0001), Region Ile-de-France (DIM-ACAV), Region Alsace (contrat CPER), Region Provence-AlpesCote d'Azur, Departement du Var and Ville de La Seyne-sur-Mer, France; Bundesministerium fur Bildung und Forschung (BMBF), Germany; Instituto Nazionale di Fisica Nucleare(INFN), Italy; Nederlandse Organisatie voor Wetenschappelijk Onderzoek(NWO), the Netherlands; Council of the President of the Russian Federation for young scientists and leading scientific schools supporting grants, Russia; Executive Unit for Financing Higher Education, Research, Development and Innovation (UEFISCDI), Romania; Ministerio de Ciencia e Innovacion (MCI) and Agencia Estatal de Investigacion: Programa Estatal de Generacion de Conocimiento (refs. PGC2018096663-B-C41, -A-C42, -B-C43, -B-C44) (MCI/FEDER), Severo Ochoa Centre of Excellence and MultiDark Consolider, Junta de Andalucia (ref. SOMM17/6104/UGR and A-FQM-053-UGR18), Generalitat Valenciana: Grisolia (ref. GRISOLIA/2018/119) and GenT (ref. CIDEGENT/2018/034) programs, Spain; Ministry of Higher Education, Scientific Research and Professional Training, Morocco. We also acknowledge the technical support of Ifremer, AIM and Foselev Marine for the sea operation and the CC-IN2P3 for the computing facilities. The authors acknowledge the financial support of the funding agencies: Centre National de la Recherche Scientifique (CNRS), Commissariat a l'Energie Atomique et aux Energies Alternatives(CEA), Commission Europeenne (FEDER fund and Marie Curie Program), Institut Universitaire de France (IUF), Labex UnivEarthS(ANR-10-LABX-0023 and ANR-18-IDEX-0001), Region Ile-de-France (DIM-ACAV), Region Alsace (contrat CPER), Region Provence-AlpesCote d'Azur, Departement du Var and Ville de La Seyne-sur-Mer, France; Bundesministerium fur Bildung und Forschung (BMBF), Germany; Instituto Nazionale di Fisica Nucleare(INFN), Italy; Nederlandse Organisatie voor Wetenschappelijk Onderzoek(NWO), the Netherlands; Council of the President of the Russian Federation for young scientists and leading scientific schools supporting grants, Russia; Executive Unit for Financing Higher Education, Research, Development and Innovation (UEFISCDI), Romania; Ministerio de Ciencia e Innovacion (MCI) and Agencia Estatal de Investigacion: Programa Estatal de Generacion de Conocimiento (refs. PGC2018096663-B-C41, -A-C42, -B-C43, -B-C44) (MCI/FEDER), Severo Ochoa Centre of Excellence and MultiDark Consolider, Junta de Andalucia (ref. SOMM17/6104/UGR and A-FQM-053-UGR18), Generalitat Valenciana: Grisolia (ref. GRISOLIA/2018/119) and GenT (ref. CIDEGENT/2018/034) programs, Spain; Ministry of Higher Education, Scientific Research and Professional Training, Morocco. We also acknowledge the technical support of Ifremer, AIM and Foselev Marine for the sea operation and the CC-IN2P3 for the computing facilities., This letter presents a combined measurement of the energy spectra of atmospheric nu(e) and nu(mu) in the energy range between similar to 100 GeV and similar to 50 TeV with the ANTARES neutrino telescope. The analysis uses 3012 days of detector livetime in the period 2007-2017, and selects 1016 neutrinos interacting in (or close to) the instrumented volume of the detector, yielding shower-like events (mainly from nu(e) + (nu) over bar (e) charged current plus all neutrino neutral current interactions) and starting track events (mainly from nu(mu) + (nu) over bar (mu) charged current interactions). The contamination by atmospheric muons in the final sample is suppressed at the level of a few per mill by different steps in the selection analysis, including a Boosted Decision Tree classifier. The distribution of reconstructed events is unfolded in terms of electron and muon neutrino fluxes. The derived energy spectra are compared with previous measurements that, above 100 GeV, are limited to experiments in polar ice and, for nu(mu), to Super-Kamiokande., Centre National de la Recherche Scientifique (CNRS), French Atomic Energy Commission, Commission Europeenne (FEDER fund), Institut Universitaire de France (IUF), Labex UnivEarthS ANR-10-LABX-0023 ANR-18-IDEX-0001, Region Ile-de-France, Region Grand-Est, Region Provence-Alpes-Cote d'Azur, Federal Ministry of Education & Research (BMBF), Instituto Nazionale di Fisica Nucleare(INFN), Italy, Netherlands Organization for Scientific Research (NWO), Netherlands Government, Council of the President of the Russian Federation for young scientists and leading scientific schools supporting grants, Russia, Consiliul National al Cercetarii Stiintifice (CNCS), Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii (UEFISCDI), Spanish Government PGC2018096663-B-C41 PGC2018096663-A-C42 PGC2018096663-B-C43 PGC2018096663-B-C44, Severo Ochoa Centre of Excellence and MultiDark Consolider, Junta de Andalucia SOMM17/6104/UGR A-FQM-053-UGR18, Generalitat Valenciana: Grisolia program, Spain GRISOLIA/2018/119, Generalitat Valenciana: GenT program, Spain CIDEGENT/2018/034, Ministry of Higher Education, Scientific Research and Professional Training, Morocco, Agencia Estatal de Investigacion PGC2018096663-B-C41 PGC2018096663-A-C42 PGC2018096663-B-C43 PGC2018096663-B-C44, Commission Europeenne (Marie Curie Program)
Published: 2021

28. KM3NeT front-end and readout electronics system: hardware, firmware and software

Author: Sebastiano Aiello, Annarita Margiotta, Antonio Marinelli, Christos Markou, Gregory Martignac, Lilian Martin, Juan A. Martínez-Mora, Agnese Martini, Fabio Marzaioli, Safaa Mazzou, Rosa Mele, Karel W. Melis, Pasquale Migliozzi, Emilio Migneco, Piotr Mijakowski, Luis S. Miranda, Carlos M. Mollo, Mauro Morganti, Michael Moser, Abdelilah Moussa, Rasa Muller, Paolo Musico, Mario Musumeci, Lodewijk Nauta, Sergio Navas, Carlo A. Nicolau, Christine Nielsen, Brian Ó Fearraigh, Mukharbek Organokov, Angelo Orlando, Gogita Papalashvili, Riccardo Papaleo, Cosimo Pastore, Gabriela E. Păvălaş, Giuliano Pellegrini, Carmelo Pellegrino, Mathieu Perrin-Terrin, Paolo Piattelli, Camiel Pieterse, Konstantinos Pikounis, Ofelia Pisanti, Chiara Poirè, Georgia Polydefki, Vlad Popa, Maarten Post, Thierry Pradier, Gerd Pühlhofer, Sara Pulvirenti, Liam Quinn, Fabrizio Raffaelli, Nunzio Randazzo, Antonio Rapicavoli, Soebur Razzaque, Diego Real, Stefan Reck, Jonas Reubelt, Giorgio Riccobene, Marc Richer, Louis Rigalleau, Alberto Rovelli, Ilenia Salvadori, Dorothea F. E. Samtleben, Agustin Sánchez Losa, Matteo Sanguineti, Andrea Santangelo, Domenico Santonocito, Piera Sapienza, Jan-Willem Schmelling, Jutta Schnabel, Virginia Sciacca, Jordan Seneca, Irene Sgura, Rezo Shanidze, Ankur Sharma, Francesco Simeone, Anna Sinopoulou, Bernardino Spisso, Maurizio Spurio, Dimitris Stavropoulos, Jos Steijger, Simona M. Stellacci, Bruno Strandberg, Dominik Stransky, Mauro Taiuti, Yahya Tayalati, Enrique Tenllado, Tarak Thakore, Paul Timmer, Steven Tingay, Ekaterini Tzamariudaki, Dimitrios Tzanetatos, Veronique Van Elewyck, Federico Versari, Salvo Viola, Daniele Vivolo, Gwenhael de Wasseige, Joern Wilms, Rafał Wojaczyński, Els de Wolf, Dmitry Zaborov, Angela Zegarelli, Juan D. Zornoza, Juan Zúñiga, Vasilis Panagopoulos, Fabrizio Ameli, Michel Andre, Giorgos Androulakis, Marco Anghinolfi, Gisela Anton, Miquel Ardid, Julien Aublin, Christos Bagatelas, Giancarlo Barbarino, Bruny Baret, Suzan Basegmez du Pree, Anastasios Belias, Meriem Bendahman, Edward Berbee, Ad M. van den Berg, Vincent Bertin, Vincent van Beveren, Simone Biagi, Andrea Biagioni, Matthias Bissinger, Pascal Bos, Jihad Boumaaza, Simon Bourret, Mohammed Bouta, Gilles Bouvet, Mieke Bouwhuis, Cristiano Bozza, Horea Brânzaş, Max M. Briel, Marc Bruchner, Ronald Bruijn, Jurgen Brunner, Ernst-Jan Buis, Raffaele Buompane, Jose Busto, David Calvo, Antonio Capone, Silvia Celli, Mohamed Chabab, Nhan Chau, Silvio Cherubini, Vitaliano Chiarella, Tommaso Chiarusi, Marco Circella, Rosanna Cocimano, Joao A. B. Coelho, Alexis Coleiro, Marta C. Molla, Stephane Colonges, Rosa Coniglione, Paschal Coyle, Alexandre Creusot, Giacomo Cuttone, Antonio D’Amico, Antonio D’Onofrio, Richard Dallier, Mauro De Palma, Irene Di Palma, Antonio F. Díaz, Didac Diego-Tortosa, Carla Distefano, Alba Domi, Roberto Donà, Corinne Donzaud, Damien Dornic, Manuel Dörr, Mora Durocher, Thomas Eberl, Thijs van Eeden, Imad El Bojaddaini, Hassnae Eljarrari, Dominik Elsaesser, Alexander Enzenhöfer, Paolo Fermani, Giovanna Ferrara, Miroslav D. Filipović, Luigi A. Fusco, Deepak Gajanana, Tamas Gal, Alfonso Garcia Soto, Fabio Garufi, Lucio Gialanella, Emidio Giorgio, Sara R. Gozzini, Rodrigo Gracia, Kay Graf, Dario Grasso, Timothee Grégoire, Giuseppe Grella, Daniel Guderian, Carlo Guidi, Steffen Hallmann, Hassane Hamdaoui, Hans van Haren, Aart Heijboer, Amar Hekalo, Juan J. Hernández-Rey, Jannik Hofestädt, Feifei Huang, Enrique H. Santiago, Giulia Illuminati, Clancy W. James, Peter Jansweijer, Martijn Jongen, Maarten de Jong, Paul de Jong, Matthias Kadler, Piotr Kalaczyński, Oleg Kalekin, Uli F. Katz, Nafis R. Khan Chowdhury, Frits van der Knaap, Els N. Koffeman, Paul Kooijman, Antoine Kouchner, Michael Kreter, Vladimir Kulikovskiy, Robert Lahmann, Giuseppina Larosa, Remy Le Breton, Francesco Leone, Emanuele Leonora, Giuseppe Levi, Massimiliano Lincetto, Miles Lindsey Clark, Alessandro Lonardo, Fabio Longhitano, Daniel Lopez-Coto, Giuliano Maggi, Jerzy Mańczak, Karl Mannheim, AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Laboratoire de physique subatomique et des technologies associées (SUBATECH), Université de Nantes - Faculté des Sciences et des Techniques, Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Institut de Recherches Subatomiques (IReS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Cancéropôle du Grand Est-Centre National de la Recherche Scientifique (CNRS), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), KM3NeT, Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Aiello, Sebastiano, Margiotta, Annarita, Marinelli, Antonio, Markou, Christo, Martignac, Gregory, Martin, Lilian, Martínez-Mora, Juan A., Martini, Agnese, Marzaioli, Fabio, Mazzou, Safaa, Mele, Rosa, Melis, Karel W., Migliozzi, Pasquale, Migneco, Emilio, Mijakowski, Piotr, Miranda, Luis S., Mollo, Carlos M., Morganti, Mauro, Moser, Michael, Moussa, Abdelilah, Muller, Rasa, Musico, Paolo, Musumeci, Mario, Nauta, Lodewijk, Navas, Sergio, Nicolau, Carlo A., Nielsen, Christine, Fearraigh, Brian Ó, Organokov, Mukharbek, Orlando, Angelo, Papalashvili, Gogita, Papaleo, Riccardo, Pastore, Cosimo, Păvălaş, Gabriela E., Pellegrini, Giuliano, Pellegrino, Carmelo, Perrin-Terrin, Mathieu, Piattelli, Paolo, Pieterse, Camiel, Pikounis, Konstantino, Pisanti, Ofelia, Poirè, Chiara, Polydefki, Georgia, Popa, Vlad, Post, Maarten, Pradier, Thierry, Pühlhofer, Gerd, Pulvirenti, Sara, Quinn, Liam, Raffaelli, Fabrizio, Randazzo, Nunzio, Rapicavoli, Antonio, Razzaque, Soebur, Real, Diego, Reck, Stefan, Reubelt, Jona, Riccobene, Giorgio, Richer, Marc, Rigalleau, Loui, Rovelli, Alberto, Salvadori, Ilenia, Samtleben, Dorothea F. E., Sánchez Losa, Agustin, Sanguineti, Matteo, Santangelo, Andrea, Santonocito, Domenico, Sapienza, Piera, Schmelling, Jan-Willem, Schnabel, Jutta, Sciacca, Virginia, Seneca, Jordan, Sgura, Irene, Shanidze, Rezo, Sharma, Ankur, Simeone, Francesco, Sinopoulou, Anna, Spisso, Bernardino, Spurio, Maurizio, Stavropoulos, Dimitri, Steijger, Jo, Stellacci, Simona M., Strandberg, Bruno, Stransky, Dominik, Taiuti, Mauro, Tayalati, Yahya, Tenllado, Enrique, Thakore, Tarak, Timmer, Paul, Tingay, Steven, Tzamariudaki, Ekaterini, Tzanetatos, Dimitrio, Van Elewyck, Veronique, Versari, Federico, Viola, Salvo, Vivolo, Daniele, de Wasseige, Gwenhael, Wilms, Joern, Wojaczyński, Rafał, de Wolf, El, Zaborov, Dmitry, Zegarelli, Angela, Zornoza, Juan D., Zúñiga, Juan, Panagopoulos, Vasili, Ameli, Fabrizio, Andre, Michel, Androulakis, Giorgo, Anghinolfi, Marco, Anton, Gisela, Ardid, Miquel, Aublin, Julien, Bagatelas, Christo, Barbarino, Giancarlo, Baret, Bruny, Basegmez du Pree, Suzan, Belias, Anastasio, Bendahman, Meriem, Berbee, Edward, van den Berg, Ad M., Bertin, Vincent, van Beveren, Vincent, Biagi, Simone, Biagioni, Andrea, Bissinger, Matthia, Bos, Pascal, Boumaaza, Jihad, Bourret, Simon, Bouta, Mohammed, Bouvet, Gille, Bouwhuis, Mieke, Bozza, Cristiano, Brânzaş, Horea, Briel, Max M., Bruchner, Marc, Bruijn, Ronald, Brunner, Jurgen, Buis, Ernst-Jan, Buompane, Raffaele, Busto, Jose, Calvo, David, Capone, Antonio, Celli, Silvia, Chabab, Mohamed, Chau, Nhan, Cherubini, Silvio, Chiarella, Vitaliano, Chiarusi, Tommaso, Circella, Marco, Cocimano, Rosanna, Coelho, Joao A. B., Coleiro, Alexi, Molla, Marta C., Colonges, Stephane, Coniglione, Rosa, Coyle, Paschal, Creusot, Alexandre, Cuttone, Giacomo, D’Amico, Antonio, D’Onofrio, Antonio, Dallier, Richard, De Palma, Mauro, Di Palma, Irene, Díaz, Antonio F., Diego-Tortosa, Didac, Distefano, Carla, Domi, Alba, Donà, Roberto, Donzaud, Corinne, Dornic, Damien, Dörr, Manuel, Durocher, Mora, Eberl, Thoma, van Eeden, Thij, El Bojaddaini, Imad, Eljarrari, Hassnae, Elsaesser, Dominik, Enzenhöfer, Alexander, Fermani, Paolo, Ferrara, Giovanna, Filipović, Miroslav D., Fusco, Luigi A., Gajanana, Deepak, Gal, Tama, Garcia Soto, Alfonso, Garufi, Fabio, Gialanella, Lucio, Giorgio, Emidio, Gozzini, Sara R., Gracia, Rodrigo, Graf, Kay, Grasso, Dario, Grégoire, Timothee, Grella, Giuseppe, Guderian, Daniel, Guidi, Carlo, Hallmann, Steffen, Hamdaoui, Hassane, van Haren, Han, Heijboer, Aart, Hekalo, Amar, Hernández-Rey, Juan J., Hofestädt, Jannik, Huang, Feifei, Santiago, Enrique H., Illuminati, Giulia, James, Clancy W., Jansweijer, Peter, Jongen, Martijn, de Jong, Maarten, de Jong, Paul, Kadler, Matthia, Kalaczyński, Piotr, Kalekin, Oleg, Katz, Uli F., Khan Chowdhury, Nafis R., van der Knaap, Frit, Koffeman, Els N., Kooijman, Paul, Kouchner, Antoine, Kreter, Michael, Kulikovskiy, Vladimir, Lahmann, Robert, Larosa, Giuseppina, Le Breton, Remy, Leone, Francesco, Leonora, Emanuele, Levi, Giuseppe, Lincetto, Massimiliano, Lindsey Clark, Mile, Lonardo, Alessandro, Longhitano, Fabio, Lopez-Coto, Daniel, Maggi, Giuliano, Mańczak, Jerzy, Mannheim, Karl, Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, Sebastiano Aiello, Fabrizio Ameli, Michel Andre, Giorgos Androulaki, Marco Anghinolfi, Gisela Anton, Miquel Ardid, Julien Aublin, Christos Bagatela, Giancarlo Barbarino, Bruny Baret, Suzan Basegmez du Pree, Anastasios Belia, Meriem Bendahman, Edward Berbee, Ad M. van den Berg, Vincent Bertin, Vincent van Beveren, Simone Biagi, Andrea Biagioni, Matthias Bissinger, Pascal Bo, Jihad Boumaaza, Simon Bourret, Mohammed Bouta, Gilles Bouvet, Mieke Bouwhui, Cristiano Bozza, Horea Brânza, Max M. Briel, Marc Bruchner, Ronald Bruijn, Jurgen Brunner, Ernst-Jan Bui, Raffaele Buompane, Jose Busto, David Calvo, Antonio Capone, Silvia Celli, Mohamed Chabab, Nhan Chau, Silvio Cherubini, Vitaliano Chiarella, Tommaso Chiarusi, Marco Circella, Rosanna Cocimano, Joao A. B. Coelho, Alexis Coleiro, Marta C. Molla, Stephane Colonge, Rosa Coniglione, Paschal Coyle, Alexandre Creusot, Giacomo Cuttone, Antonio D’Amico, Antonio D’Onofrio, Richard Dallier, Mauro De Palma, Irene Di Palma, Antonio F. Díaz, Didac Diego-Tortosa, Carla Distefano, Alba Domi, Roberto Donà, Corinne Donzaud, Damien Dornic, Manuel Dörr, Mora Durocher, Thomas Eberl, Thijs van Eeden, Imad El Bojaddaini, Hassnae Eljarrari, Dominik Elsaesser, Alexander Enzenhöfer, Paolo Fermani, Giovanna Ferrara, Miroslav D. Filipovic ́, Luigi A. Fusco, Deepak Gajanana, Tamas Gal, Alfonso Garcia Soto, Fabio Garufi, Lucio Gialanella, Emidio Giorgio, Sara R. Gozzini, Rodrigo Gracia, Kay Graf, Dario Grasso, Timothee Grégoire, Giuseppe Grella, Daniel Guderian, Carlo Guidi, Steffen Hallmann, Hassane Hamdaoui, Hans van Haren, Aart Heijboer, Amar Hekalo, Juan J. Hernández-Rey, Jannik Hofestädt, Feifei Huang, Enrique H. Santiago, Giulia Illuminati, Clancy W. Jame, Peter Jansweijer, Martijn Jongen, Maarten de Jong, Paul de Jong, Matthias Kadler, Piotr Kalaczynski, Oleg Kalekin, Uli F. Katz, Nafis R. Khan Chowdhury, Frits van der Knaap, Els N. Koffeman, Paul Kooijman, Antoine Kouchner, Michael Kreter, Vladimir Kulikovskiy, Robert Lahmann, Giuseppina Larosa, Remy Le Breton, Francesco Leone, Emanuele Leonora, Giuseppe Levi, Massimiliano Lincetto, Miles Lindsey Clark, Alessandro Lonardo, Fabio Longhitano, Daniel Lopez-Coto, Giuliano Maggi, Jerzy Ma ́nczak, Karl Mannheim, Annarita Margiotta, Antonio Marinelli, Christos Markou, Gregory Martignac, Lilian Martin, Juan A. Martínez-Mora, Agnese Martini, Fabio Marzaioli, Safaa Mazzou, Rosa MeleKarel W. Meli, Pasquale Migliozzi, Emilio Migneco, Piotr Mijakowski, Luis S. Miranda, Carlos M. Mollo, Mauro Morganti, Michael Moser, Abdelilah Moussa, Rasa Muller, Paolo Musico, Mario Musumeci, Lodewijk Nauta, Sergio Nava, Carlo A. Nicolau, Christine Nielsen, Brian Ó Fearraigh, Mukharbek Organokov, Angelo Orlando, Vasilis Panagopoulo, Gogita Papalashvili, Riccardo Papaleo, Cosimo Pastore, Gabriela E. Păvăla ̧, Giuliano Pellegrini, Carmelo Pellegrino, Mathieu Perrin-Terrin, Paolo Piattelli, Camiel Pieterse, Konstantinos Pikouni, Ofelia Pisanti, Chiara Poirè, Georgia Polydefki, Vlad Popa, Maarten Post, Thierry Pradier, Gerd Pühlhofer, Sara Pulvirenti, Liam Quinn, Fabrizio Raffaelli, Nunzio Randazzo, Antonio Rapicavoli, Soebur Razzaque, Diego Real, Stefan Reck, Jonas Reubelt, Giorgio Riccobene, Marc Richer, Louis Rigalleau, Alberto Rovelli, Ilenia Salvadori, Dorothea F. E. Samtleben, Agustin Sánchez Losa, Matteo Sanguineti, Andrea Santangelo, Domenico Santonocito, Piera Sapienza, Jan-Willem Schmelling, Jutta Schnabel, Virginia Sciacca, Jordan Seneca, Irene Sgura, Rezo Shanidze, Ankur Sharma, Francesco Simeone, Anna Sinopoulou, Bernardino Spisso, Maurizio Spurio, Dimitris Stavropoulo, Jos Steijger, Simona M. Stellacci, Bruno Strandberg, Dominik Stransky, Mauro Taiuti, Yahya Tayalati, Enrique Tenllado, Tarak Thakore, Paul Timmer, Steven Tingay, Ekaterini Tzamariudaki, Dimitrios Tzanetato, Veronique Van Elewyck, Federico Versari, Salvo Viola, Daniele Vivolo, Gwenhael de Wasseige, Joern Wilm, Rafał Wojaczy ́nski, Els de Wolf, Dmitry Zaborov, Angela Zegarelli, Juan D. Zornoza, Juan Zúñiga, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Research unit Astroparticle Physics, and 33379009 - Kreter, Michael
Subjects: Astrofísica, data acquisition, Computer science, Physics::Instrumentation and Detectors, readout electronics, sensors, Astrophysics, Neutrino telescope, computer.software_genre, 7. Clean energy, 01 natural sciences, Signal, Synchronization (alternating current), Front and back ends, Front-end electronics, readout electronics, neutrino telescope, KM3NeT, Front-end electronics, KM3NeT, Readout electronics, 010303 astronomy & astrophysics, Instrumentation, field programmable gate arrays, Firmware, electronics, 4. Education, Electrical engineering, Astrophysics::Instrumentation and Methods for Astrophysics, front-end electronics, Electronic, Optical and Magnetic Materials, Astrophysics - Instrumentation and Methods for Astrophysics, Photomultiplier, clocks, front-end electronic, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, Partícules (Física nuclear), 010309 optics, 0103 physical sciences, Neutrins, readout electronic, 14. Life underwater, Electronics, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Instrumentation and Methods for Astrophysics (astro-ph.IM), Cherenkov radiation, Particles (Nuclear physics), Detectors òptics, logic, Optical detectors, Física [Àrees temàtiques de la UPC], Telescopis, business.industry, Mechanical Engineering, neutrino telescope, Astronomy and Astrophysics, Space and Planetary Science, Control and Systems Engineering, FISICA APLICADA, business, computer, Telescopes
Abstract: [EN] The KM3NeT research infrastructure being built at the bottom of the Mediterranean Sea will host water-Cherenkov telescopes for the detection of cosmic neutrinos. The neutrino telescopes will consist of large volume three-dimensional grids of optical modules to detect the Cherenkov light from charged particles produced by neutrino-induced interactions. Each optical module houses 31 3-in. photomultiplier tubes, instrumentation for calibration of the photomultiplier signal and positioning of the optical module, and all associated electronics boards. By design, the total electrical power consumption of an optical module has been capped at seven Watts. We present an overview of the front-end and readout electronics system inside the optical module, which has been designed for a 1-ns synchronization between the clocks of all optical modules in the grid during a life time of at least 20 years., The authors acknowledge financial support from the funding agencies: Agence Nationale de la Recherche (Grant No. ANR-15-CE31-0020), Centre National de la Recherche Scientifique (CNRS), Commission Europeenne (FEDER fund and Marie Curie Program), Institut Universitaire de France (IUF), IdEx program and UnivEarthS Labex program at Sorbonne Paris Cite (Grant Nos. ANR-10-LABX-0023 and ANR-11-IDEX-0005-02), Paris Ile-de-France Region, France; Shota Rustaveli National Science Foundation of Georgia (SRNSFG, Grant No. FR-18-1268), Georgia; Deutsche Forschungsgemeinschaft (DFG), Germany; The General Secretariat of Research and Technology (GSRT), Greece; Istituto Nazionale di Fisica Nucleare (INFN), Ministero dell'Istruzione, dell'Universita e della Ricerca (MIUR), PRIN 2017 program (Grant NAT-NET 2017W4HA7S) Italy; Ministry of Higher Education, Scientific Research and Professional Training, Morocco; Nederlandse organisatie voor Wetenschappelijk Onderzoek (NWO), the Netherlands; The National Science Centre, Poland (2015/18/E/ST2/00758); National Authority for Scientific Research (ANCS), Romania; Plan Estatal de Investigacion [refs. FPA2015-65150-C3-1-P, -2-P and -3-P, (MINECO/FEDER)], Severo Ochoa Centre of Excellence program (MINECO), Red Consolider MultiDark (ref. FPA2017-90566-REDC, MINECO), and Prometeo and Grisolia programs (Generalitat Valenciana), "la Caixa" Foundation (ID 100010434) through the fellowship LCF/BQ/IN17/11620019, and the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No. 713673, Spain.
Published: 2019

29. gSeaGen: The KM3NeT GENIE-based code for neutrino telescopes

Author: Jutta Schnabel, S. Reck, G. Vannoye, L. Maderer, D. van Eijk, J. Brunner, Rosanna Cocimano, Fabio Longhitano, D. Guderian, F. Versari, Kay Graf, Karel Melis, P. Migliozzi, C. Pastore, Diego Real, A. Franco, Zineb Aly, J. Reubelt, M. Perrin-Terrin, Carlo Alessandro Nicolau, Natalia Zywucka, G. Papalashvili, V. Sciacca, G. de Wasseige, Karl Mannheim, Piotr Kalaczyński, A. Martini, Z. Modebadze, M. De Palma, A. Enzenhöfer, R. Coniglione, Giuseppina Larosa, Daniele Vivolo, O. Gabella, Giuseppe Levi, J. Hofestädt, Soebur Razzaque, Paolo Fermani, Jihad Boumaaza, Luigi Antonio Fusco, S. Mastroianni, M. Organokov, B. Ó Fearraigh, N. R. Khan Chowdhury, W. Idrissi Ibnsalih, Simona Maria Stellacci, Ofelia Pisanti, Nhan Chau, S. Mazzou, M. Taiuti, M. de Jong, Gisela Anton, Alessia Capone, Carlos Maximiliano Mollo, P.M. Kooijman, Vitaliano Chiarella, M. Lindsey Clark, F. Garufi, Alice Paun, M. Ardid, Jose Busto, Tommaso Chiarusi, Paolo Castaldi, I. Sgura, T. Thakore, G.E. Păvălaş, A. Garcia Soto, E. Tzamariudaki, Thierry Pradier, S. Rivoire, S. Sánchez Navas, M. Bouta, Ornella Leonardi, Sara Pulvirenti, E. Berbee, Angelo Orlando, J. Seneca, Matthias Kadler, Joao A B Coelho, Mancia Anguita, Massimiliano Lincetto, L. Martin, Annarita Margiotta, Silvia Celli, O. Kalekin, V. Espinosa Roselló, I. El Bojaddaini, Richard Dallier, L. S. Miranda, Michel André, Andrea Santangelo, R. Le Breton, Thomas Eberl, M. Bissinger, G. Pühlhofer, A. Sharma, Dídac Diego-Tortosa, A.M. van den Berg, V. Van Elewyck, Robert Lahmann, Francesco Leone, R. Muller, S. R. Gozzini, E. Tenllado, F. Filippini, Bouke Jisse Jung, Vladimir Kulikovskiy, M. Post, Giulia Illuminati, M. Morganti, R. Donà, S.F. Biagi, E. A. De Wolf, P. Coyle, J. Manczak, Corinne Donzaud, I. Corredoira, Alexis Coleiro, Giacomo Cuttone, T. Lipreau, C. Guidi, E. Buis, S. Basegmez du Pree, Miroslav Filipovic, O. Rabyang, J. Aublin, P. Mijakowski, Damien Dornic, Jos Steijger, Bruny Baret, Sebastiano Aiello, S. Alves Garre, A. W. Chen, R. Bruijn, Riccardo Papaleo, L. Quinn, H. van Haren, G. Grella, A. Rapicavoli, K. Pikounis, G. Androulakis, G. C. Barbarino, Silvio Cherubini, J.J. Hernández-Rey, Yahya Tayalati, M. Bendahman, C. Bagatelas, Alessandro Lonardo, T. Gal, C. Distefano, D. F. E. Samtleben, A. Hekalo, Mora Durocher, U. Katz, M. Anghinolfi, A. Sinopoulou, Sandra Zavatarelli, H. Brânzaş, Mario Musumeci, S. Viola, N. Randazzo, E. Migneco, B. Spisso, M. Richer, H. Hamdaoui, M. Circella, D. Zaborov, Andrea Biagioni, L. Nauta, Matteo Sanguineti, R. Wojaczyński, G. Ferrara, G. Riccobene, R. Gracia, Els Koffeman, V. Bertin, D. Drouhin, Fabio Marzaioli, F. Raffaelli, Markus Boettcher, F. Huang, C. Poirè, P. Piattelli, Antonio D'Onofrio, Jörn Wilms, Emanuele Leonora, Mohamed Chabab, M. Bruchner, Arnauld Albert, F. van der Knaap, C. Markou, D. Tzanetatos, Cristiano Bozza, Lucio Gialanella, G. Vasileiadis, F. Salesa Greus, J.D. Zornoza, Y. Gatelet, Steven Tingay, V. Carretero, Domenico Santonocito, Michael Moser, C. Pieterse, C. W. James, Antoine Kouchner, A. Zegarelli, Paolo Sapienza, M. Colomer Molla, Dominik Elsaesser, C. Pellegrino, P. de Jong, D. Stavropoulos, A. Rovelli, Abdelilah Moussa, Michael Kreter, A. Marinelli, N. Geißelbrecht, A. Sánchez Losa, A. Creusot, Maurizio Spurio, A.J. Heijboer, M.C. Bouwhuis, Raffaele Buompane, Gennaro Miele, Alba Domi, D. Calvo, I. Di Palma, Antonio F. Díaz, J. Zúñiga, D. Lopez-Coto, J.A. Martínez-Mora, Dario Grasso, Fabrizio Ameli, V. Popa, Francesco Simeone, Emidio Giorgio, Steffen Hallmann, M. Dörr, Rezo Shanidze, Ministerio de Ciencia e Innovación (España), Generalitat Valenciana, 24420530 - Böttcher, Markus, 33379009 - Kreter, Michael, 34208968 - Zywucka-Hejzner, Natalia, 27743268 - Rabyang, O., Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, Aiello S., Albert A., Garre S.A., Aly Z., Ameli F., Andre M., Androulakis G., Anghinolfi M., Anguita M., Anton G., Ardid M., Aublin J., Bagatelas C., Barbarino G., Baret B., Basegmez du Pree S., Bendahman M., Berbee E., van den Berg A.M., Bertin V., Biagi S., Biagioni A., Bissinger M., Boettcher M., Boumaaza J., Bouta M., Bouwhuis M., Bozza C., Branzas H., Bruchner M., Bruijn R., Brunner J., Buis E., Buompane R., Busto J., Calvo D., Capone A., Carretero V., Castaldi P., Celli S., Chabab M., Chau N., Chen A., Cherubini S., Chiarella V., Chiarusi T., Circella M., Cocimano R., Coelho J.A.B., Coleiro A., Molla M.C., Coniglione R., Corredoira I., Coyle P., Creusot A., Cuttone G., D'Onofrio A., Dallier R., De Palma M., Di Palma I., Diaz A.F., Diego-Tortosa D., Distefano C., Domi A., Dona R., Donzaud C., Dornic D., Dorr M., Drouhin D., Durocher M., Eberl T., van Eijk D., El Bojaddaini I., Elsaesser D., Enzenhofer A., Rosello V.E., Fermani P., Ferrara G., Filipovic M.D., Filippini F., Franco A., Fusco L.A., Gabella O., Gal T., Soto A.G., Garufi F., Gatelet Y., Geisselbrecht N., Gialanella L., Giorgio E., Gozzini S.R., Gracia R., Graf K., Grasso D., Grella G., Guderian D., Guidi C., Hallmann S., Hamdaoui H., van Haren H., Heijboer A., Hekalo A., Hernandez-Rey J.J., Hofestadt J., Huang F., Ibnsalih W.I., Illuminati G., James C.W., de Jong M., de Jong P., Jung B.J., Kadler M., Kalaczynski P., Kalekin O., Katz U.F., Chowdhury N.R.K., van der Knaap F., Koffeman E.N., Kooijman P., Kouchner A., Kreter M., Kulikovskiy V., Lahmann R., Larosa G., Le Breton R., Leonardi O., Leone F., Leonora E., Levi G., Lincetto M., Lindsey Clark M., Lipreau T., Lonardo A., Longhitano F., Lopez-Coto D., Maderer L., Manczak J., Mannheim K., Margiotta A., Marinelli A., Markou C., Martin L., Martinez-Mora J.A., Martini A., Marzaioli F., Mastroianni S., Mazzou S., Melis K.W., Miele G., Migliozzi P., Migneco E., Mijakowski P., Miranda L.S., Modebadze Z., Mollo C.M., Morganti M., Moser M., Moussa A., Muller R., Musumeci M., Nauta L., Navas S., Nicolau C.A., O Fearraigh B., Organokov M., Orlando A., Papalashvili G., Papaleo R., Pastore C., Paun A.M., Pavalas G.E., Pellegrino C., Perrin-Terrin M., Piattelli P., Pieterse C., Pikounis K., Pisanti O., Poire C., Popa V., Post M., Pradier T., Puhlhofer G., Pulvirenti S., Quinn L., Rabyang O., Raffaelli F., Randazzo N., Rapicavoli A., Razzaque S., Real D., Reck S., Reubelt J., Riccobene G., Richer M., Rivoire S., Rovelli A., Greus F.S., Samtleben D.F.E., Losa A.S., Sanguineti M., Santangelo A., Santonocito D., Sapienza P., Schnabel J., Sciacca V., Seneca J., Sgura I., Shanidze R., Sharma A., Simeone F., Sinopoulou A., Spisso B., Spurio M., Stavropoulos D., Steijger J., Stellacci S.M., Taiuti M., Tayalati Y., Tenllado E., Thakore T., Tingay S., Tzamariudaki E., Tzanetatos D., Van Elewyck V., Vannoye G., Vasileiadis G., Versari F., Viola S., Vivolo D., de Wasseige G., Wilms J., Wojaczynski R., de Wolf E., Zaborov D., Zavatarelli S., Zegarelli A., Zornoza J.D., Zuniga J., Zywucka N., Institut Pluridisciplinaire Hubert Curien (IPHC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Groupe de Recherche en Physique des Hautes Energies (GRPHE), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut Universitaire de Technologie de Colmar, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Laboratoire de physique subatomique et des technologies associées (SUBATECH), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Laboratoire Univers et Particules de Montpellier (LUPM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Montpellier 2 - Sciences et Techniques (UM2), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), KM3NeT, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-IUT de Colmar, Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), ANR-15-CE31-0020,DAEMONS,Démonstration de la possibilité d'établir l'ordonnancement des masses de neutrinos dans la mer(2015), ANR-10-LABX-0023,UnivEarthS,Earth - Planets - Universe: observation, modeling, transfer(2010), ANR-11-IDEX-0005,USPC,Université Sorbonne Paris Cité(2011), Aiello, S., Albert, A., Garre, S. A., Aly, Z., Ameli, F., Andre, M., Androulakis, G., Anghinolfi, M., Anguita, M., Anton, G., Ardid, M., Aublin, J., Bagatelas, C., Barbarino, G., Baret, B., Basegmez du Pree, S., Bendahman, M., Berbee, E., van den Berg, A. M., Bertin, V., Biagi, S., Biagioni, A., Bissinger, M., Boettcher, M., Boumaaza, J., Bouta, M., Bouwhuis, M., Bozza, C., Branzas, H., Bruchner, M., Bruijn, R., Brunner, J., Buis, E., Buompane, R., Busto, J., Calvo, D., Capone, A., Carretero, V., Castaldi, P., Celli, S., Chabab, M., Chau, N., Chen, A., Cherubini, S., Chiarella, V., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Molla, M. C., Coniglione, R., Corredoira, I., Coyle, P., Creusot, A., Cuttone, G., D'Onofrio, A., Dallier, R., De Palma, M., Di Palma, I., Diaz, A. F., Diego-Tortosa, D., Distefano, C., Domi, A., Dona, R., Donzaud, C., Dornic, D., Dorr, M., Drouhin, D., Durocher, M., Eberl, T., van Eijk, D., El Bojaddaini, I., Elsaesser, D., Enzenhofer, A., Rosello, V. E., Fermani, P., Ferrara, G., Filipovic, M. D., Filippini, F., Franco, A., Fusco, L. A., Gabella, O., Gal, T., Soto, A. G., Garufi, F., Gatelet, Y., Geisselbrecht, N., Gialanella, L., Giorgio, E., Gozzini, S. R., Gracia, R., Graf, K., Grasso, D., Grella, G., Guderian, D., Guidi, C., Hallmann, S., Hamdaoui, H., van Haren, H., Heijboer, A., Hekalo, A., Hernandez-Rey, J. J., Hofestadt, J., Huang, F., Ibnsalih, W. I., Illuminati, G., James, C. W., de Jong, M., de Jong, P., Jung, B. J., Kadler, M., Kalaczynski, P., Kalekin, O., Katz, U. F., Chowdhury, N. R. K., van der Knaap, F., Koffeman, E. N., Kooijman, P., Kouchner, A., Kreter, M., Kulikovskiy, V., Lahmann, R., Larosa, G., Le Breton, R., Leonardi, O., Leone, F., Leonora, E., Levi, G., Lincetto, M., Lindsey Clark, M., Lipreau, T., Lonardo, A., Longhitano, F., Lopez-Coto, D., Maderer, L., Manczak, J., Mannheim, K., Margiotta, A., Marinelli, A., Markou, C., Martin, L., Martinez-Mora, J. A., Martini, A., Marzaioli, F., Mastroianni, S., Mazzou, S., Melis, K. W., Miele, G., Migliozzi, P., Migneco, E., Mijakowski, P., Miranda, L. S., Modebadze, Z., Mollo, C. M., Morganti, M., Moser, M., Moussa, A., Muller, R., Musumeci, M., Nauta, L., Navas, S., Nicolau, C. A., O Fearraigh, B., Organokov, M., Orlando, A., Papalashvili, G., Papaleo, R., Pastore, C., Paun, A. M., Pavalas, G. E., Pellegrino, C., Perrin-Terrin, M., Piattelli, P., Pieterse, C., Pikounis, K., Pisanti, O., Poire, C., Popa, V., Post, M., Pradier, T., Puhlhofer, G., Pulvirenti, S., Quinn, L., Rabyang, O., Raffaelli, F., Randazzo, N., Rapicavoli, A., Razzaque, S., Real, D., Reck, S., Reubelt, J., Riccobene, G., Richer, M., Rivoire, S., Rovelli, A., Greus, F. S., Samtleben, D. F. E., Losa, A. S., Sanguineti, M., Santangelo, A., Santonocito, D., Sapienza, P., Schnabel, J., Sciacca, V., Seneca, J., Sgura, I., Shanidze, R., Sharma, A., Simeone, F., Sinopoulou, A., Spisso, B., Spurio, M., Stavropoulos, D., Steijger, J., Stellacci, S. M., Taiuti, M., Tayalati, Y., Tenllado, E., Thakore, T., Tingay, S., Tzamariudaki, E., Tzanetatos, D., Van Elewyck, V., Vannoye, G., Vasileiadis, G., Versari, F., Viola, S., Vivolo, D., de Wasseige, G., Wilms, J., Wojaczynski, R., de Wolf, E., Zaborov, D., Zavatarelli, S., Zegarelli, A., Zornoza, J. D., Zuniga, J., Zywucka, N., KM3NeT (IHEF, IoP, FNWI), ATLAS (IHEF, IoP, FNWI), and Research unit Astroparticle Physics
Subjects: Astrofísica, Physics::Instrumentation and Detectors, General Physics and Astronomy, Neutrino telescope, Astrophysics, 01 natural sciences, 010305 fluids & plasmas, astro-ph.IMA, Monte Carlo event generator, KM3NeT, neutrino: interaction, [PHYS]Physics [physics], Physics, density, 4. Education, Neutrino oscillations, Detector, neutrino: detector, Neutrino detector, statistics, Hardware and Architecture, neutrino: flavor, Neutrino, Astrophysics - Instrumentation and Methods for Astrophysics, Particle physics, Neutrino oscillation, Astrophysics::High Energy Astrophysical Phenomena, Astroparticle physics, High energy neutrinos, Neutrino telescopes, GENIE, FOS: Physical sciences, Physique [physics]/Physique [physics], Astroparticle physic, topological, 0103 physical sciences, Code (cryptography), [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Neutrins, 010306 general physics, Instrumentation and Methods for Astrophysics (astro-ph.IM), Telescopis, High Energy Physics::Phenomenology, High energy neutrino, stroparticle physics, astro-ph.IM, high energy neutrinos, FISICA APLICADA, Física::Astronomia i astrofísica [Àrees temàtiques de la UPC], High Energy Physics::Experiment, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Telescopes
Abstract: Program summary Program Title: gSeaGen CPC Library link to program files: http://dx.doi.org/10.17632/ymgxvy2br4.1 Licensing provisions: GPLv3 Programming language: C++ External routines/libraries: GENIE [1] and its external dependencies. Linkable to MUSIC [2] and PROPOSAL [3]. Nature of problem: Development of a code to generate detectable events in neutrino telescopes, using modern and maintained neutrino interaction simulation libraries which include the state-of-the-art physics models. The default application is the simulation of neutrino interactions within KM3NeT [4]. Solution method: Neutrino interactions are simulated using GENIE, a modern framework for Monte Carlo event generators. The GENIE framework, used by nearly all modern neutrino experiments, is considered as a reference code within the neutrino community. Additional comments including restrictions and unusual features: The code was tested with GENIE version 2.12.10 and it is linkable with release series 3. Presently valid up to 5 TeV. This limitation is not intrinsic to the code but due to the present GENIE valid energy range. References: [1] C. Andreopoulos at al., Nucl. Instrum. Meth. A614 (2010) 87. [2] P. Antonioli et al., Astropart. Phys. 7 (1997) 357. [3] J. H. Koehne et al., Comput. Phys. Commun. 184 (2013) 2070. [4] S. Adrián-Martínez et al., J. Phys. G: Nucl. Part. Phys. 43 (2016) 084001., The gSeaGen code is a GENIE-based application developed to efficiently generate high statistics samples of events, induced by neutrino interactions, detectable in a neutrino telescope. The gSeaGen code is able to generate events induced by all neutrino flavours, considering topological differences between tracktype and shower-like events. Neutrino interactions are simulated taking into account the density and the composition of the media surrounding the detector. The main features of gSeaGen are presented together with some examples of its application within the KM3NeT project., French National Research Agency (ANR) ANR-15-CE31-0020, Centre National de la Recherche Scientifique (CNRS), European Union (EU), Institut Universitaire de France (IUF), France, IdEx program, France, UnivEarthS Labex program at Sorbonne Paris Cite ANR-10-LABX-0023 ANR-11-IDEX-000502, Paris Ile-de-France Region, France, Shota Rustaveli National Science Foundation of Georgia (SRNSFG), Georgia FR-18-1268, German Research Foundation (DFG), Greek Ministry of Development-GSRT, Istituto Nazionale di Fisica Nucleare (INFN), Ministry of Education, Universities and Research (MIUR), PRIN 2017 program Italy NAT-NET 2017W4HA7S, Ministry of Higher Education, Scientific Research and Professional Training, Morocco, Netherlands Organization for Scientific Research (NWO) Netherlands Government, National Science Centre, Poland 2015/18/E/ST2/00758, National Authority for Scientific Research (ANCS), Romania, Ministerio de Ciencia, Innovacion, Investigacion y Universidades (MCIU): Programa Estatal de Generacion de Conocimiento, Spain (MCIU/FEDER) PGC2018-096663-B-C41 PGC2018-096663-A-C42 PGC2018-096663-BC43 PGC2018-096663-B-C44, Severo Ochoa Centre of Excellence and MultiDark Consolider (MCIU), Junta de Andalucia, Spain SOMM17/6104/UGR, Generalitat Valenciana: Grisolia, Spain GRISOLIA/2018/119, GenT, Spain CIDEGENT/2018/034, La Caixa Foundation LCF/BQ/IN17/11620019, EU: MSC program, Spain 713673
Published: 2020

30. The Control Unit of the KM3NeT Data Acquisition System

Author: A. Franco, J. Reubelt, A. Enzenhöfer, M. Taiuti, Carlos Maximiliano Mollo, A. Sinopoulou, Robert Lahmann, D. Zaborov, R. Donà, Antonio D'Onofrio, Thierry Pradier, G. Pühlhofer, G. Polydefki, Soebur Razzaque, Jörn Wilms, I. Salvadori, F. van der Knaap, S. Mazzou, F. Garufi, L. Nauta, H. Hamdaoui, V. Sciacca, M. Post, C. Markou, Gisela Anton, G. Martignac, R. Wojaczyński, G. Ferrara, M. Circella, Emanuele Leonora, E. Tzamariudaki, Nhan Chau, Vitaliano Chiarella, Riccardo Papaleo, Mohamed Chabab, Andrea Biagioni, R. Gracia, L. Quinn, M. Organokov, B. Ó Fearraigh, Matteo Sanguineti, E. Berbee, A. Rapicavoli, K. Pikounis, N. R. Khan Chowdhury, G. Androulakis, J.J. Hernández-Rey, Dominik Elsaesser, Yahya Tayalati, Francesco Leone, M. de Jong, Simona Maria Stellacci, A. Marinelli, C. Nielsen, M. De Palma, O. Kalekin, Jose Busto, G. Riccobene, Ofelia Pisanti, A. Sánchez Losa, M. Perrin-Terrin, F. Huang, Luigi Antonio Fusco, H. Brânzaş, Paolo Fermani, Rosanna Cocimano, Daniele Vivolo, I. Sgura, T. Thakore, Els Koffeman, M.C. Bouwhuis, Carlo Alessandro Nicolau, D. Tzanetatos, M. Lindsey Clark, Piotr Kalaczyński, Mario Musumeci, U. Katz, N. Randazzo, R. Mele, F. Versari, Angelo Orlando, Cristiano Bozza, M. Ardid, M. Morganti, Joao A B Coelho, P. Jansweijer, L. Martin, Silvia Celli, T. Grégoire, P. Migliozzi, Maurizio Spurio, A. Creusot, A.J. Heijboer, P. Coyle, Bruny Baret, G. Maggi, Dídac Diego-Tortosa, M. Anghinolfi, T. Gal, C. Distefano, D. F. E. Samtleben, A. Hekalo, Sara Pulvirenti, C. Pastore, V. van Beveren, Giacomo Cuttone, Alessandro Lonardo, Giuseppina Larosa, S.F. Biagi, E. A. De Wolf, Damien Dornic, Jos Steijger, M. Bouta, G. Papalashvili, Paolo Sapienza, Corinne Donzaud, Thomas Eberl, S. Viola, G. C. Barbarino, M. Durocher, E. Migneco, G. de Wasseige, M. Bissinger, Hassnae Eljarrari, A. Sharma, Karl Mannheim, Silvio Cherubini, B. Spisso, M. Richer, V. Panagopoulos, M. Bendahman, C. Bagatelas, Lucio Gialanella, J.D. Zornoza, Alessia Capone, P.M. Kooijman, J. Aublin, Matthias Kadler, Steven Tingay, J. Zúñiga, Rezo Shanidze, J. Seneca, Tommaso Chiarusi, Annarita Margiotta, G.E. Păvălaş, R. Bruijn, A. Garcia Soto, Domenico Santonocito, J.A. Martínez-Mora, Alexis Coleiro, Richard Dallier, R. Le Breton, Michael Moser, Dario Grasso, Fabrizio Ameli, S. Colonges, V. Bertin, R. Muller, Louis-Marie Rigalleau, Massimiliano Lincetto, R. Coniglione, Emidio Giorgio, Alba Domi, D. Calvo, S. R. Gozzini, J. Hofestädt, D. Lopez-Coto, Jihad Boumaaza, M. Bruchner, V. Popa, Fabio Marzaioli, Gilles Bouvet, Steffen Hallmann, H. van Haren, I. El Bojaddaini, L. S. Miranda, F. Raffaelli, S. Basegmez du Pree, Miroslav Filipovic, Andrea Santangelo, Michel André, S. Bourret, C. Poirè, P. Piattelli, A.M. van den Berg, V. Van Elewyck, P. Mijakowski, B. Strandberg, C. Pieterse, C. W. James, E. Tenllado, Giulia Illuminati, Jutta Schnabel, D. Stransky, S. Reck, G. Vannoye, D. Guderian, Kay Graf, Karel Melis, J. Brunner, Fabio Longhitano, A. Martini, Antoine Kouchner, A. Zegarelli, M. Colomer Molla, Raffaele Buompane, I. Di Palma, Antonio F. Díaz, Francesco Simeone, Vladimir Kulikovskiy, J. Manczak, C. Guidi, E. Buis, Sebastiano Aiello, G. Grella, S. Sánchez Navas, M. Dörr, C. Pellegrino, Giuseppe Levi, P. de Jong, D. Stavropoulos, A. Rovelli, Abdelilah Moussa, Diego Real, AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de physique subatomique et des technologies associées (SUBATECH), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), KM3NeT, Aiello, S., Ameli, F., Andre, M., Androulakis, G., Anghinolfi, M., Anton, G., Ardid, M., Aublin, J., Bagatelas, C., Barbarino, G., Baret, B., du Pree, S. B., Bendahman, M., Berbee, E., van den Berg, A. M., Bertin, V., van Beveren, V., Biagi, S., Biagioni, A., Bissinger, M., Boumaaza, J., Bourret, S., Bouta, M., Bouvet, G., Bouwhuis, M., Bozza, C., Branzas, H., Bruchner, M., Bruijn, R., Brunner, J., Buis, E., Buompane, R., Busto, J., Calvo, D., Capone, A., Celli, S., Chabab, M., Chau, N., Cherubini, S., Chiarella, V., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Molla, M. C., Colonges, S., Coniglione, R., Coyle, P., Creusot, A., Cuttone, G., D'Onofrio, A., Dallier, R., De Palma, M., Di Palma, I., Diaz, A. F., Diego-Tortosa, D., Distefano, C., Domi, A., Dona, R., Donzaud, C., Dornic, D., Dorr, M., Durocher, M., Eberl, T., El Bojaddaini, I., Eljarrari, H., Elsaesser, D., Enzenhofer, A., Fermani, P., Ferrara, G., Filipovic, M. D., Franco, A., Fusco, L. A., Gal, T., Soto, A. G., Garufi, F., Gialanella, L., Giorgio, E., Gozzini, S. R., Gracia, R., Graf, K., Grasso, D., Gregoire, T., Grella, G., Guderian, D., Guidi, C., Hallmann, S., Hamdaoui, H., van Haren, H., Heijboer, A., Hekalo, A., Hernandez-Rey, J. J., Hofestadt, J., Huang, F., Illuminati, G., James, C. W., Jansweijer, P., de Jong, M., de Jong, P., Kadler, M., Kalaczynski, P., Kalekin, O., Katz, U. F., Chowdhury, N. R. K., van der Knaap, F., Koffeman, E. N., Kooijman, P., Kouchner, A., Kulikovskiy, V., Lahmann, R., Larosa, G., Le Breton, R., Leone, F., Leonora, E., Levi, G., Lincetto, M., Clark, M. L., Lonardo, A., Longhitano, F., Lopez-Coto, D., Maggi, G., Manczak, J., Mannheim, K., Margiotta, A., Marinelli, A., Markou, C., Martignac, G., Martin, L., Martinez-Mora, J. A., Martini, A., Marzaioli, F., Mazzou, S., Mele, R., Melis, K. W., Migliozzi, P., Migneco, E., Mijakowski, P., Miranda, L. S., Mollo, C. M., Morganti, M., Moser, M., Moussa, A., Muller, R., Musumeci, M., Nauta, L., Navas, S., Nicolau, C. A., Nielsen, C., O Fearraigh, B., Organokov, M., Orlando, A., Panagopoulos, V., Papalashvili, G., Papaleo, R., Pastore, C., Pavalas, G. E., Pellegrino, C., Perrin-Terrin, M., Piattelli, P., Pieterse, C., Pikounis, K., Pisanti, O., Poire, C., Polydefki, G., Popa, V., Post, M., Pradier, T., Puhlhofer, G., Pulvirenti, S., Quinn, L., Raffaelli, F., Randazzo, N., Rapicavoli, A., Razzaque, S., Real, D., Reck, S., Reubelt, J., Riccobene, G., Richer, M., Rigalleau, L., Rovelli, A., Salvadori, I., Samtleben, D. F. E., Sanchez Losa, A., Sanguineti, M., Santangelo, A., Santonocito, D., Sapienza, P., Schnabel, J., Sciacca, V., Seneca, J., Sgura, I., Shanidze, R., Sharma, A., Simeone, F., Sinopoulou, A., Spisso, B., Spurio, M., Stavropoulos, D., Steijger, J., Stellacci, S. M., Strandberg, B., Stransky, D., Taiuti, M., Tayalati, Y., Tenllado, E., Thakore, T., Tingay, S., Tzamariudaki, E., Tzanetatos, D., Van Elewyck, V., Vannoye, G., Versari, F., Viola, S., Vivolo, D., de Wasseige, G., Wilms, J., Wojaczynski, R., de Wolf, E., Zaborov, D., Zegarelli, A., Zornoza, J. D., Zuniga, J., Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, KM3NeT (IHEF, IoP, FNWI), ATLAS (IHEF, IoP, FNWI), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Université de Nantes - Faculté des Sciences et des Techniques, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Research unit Astroparticle Physics, Aiello S., Ameli F., Andre M., Androulakis G., Anghinolfi M., Anton G., Ardid M., Aublin J., Bagatelas C., Barbarino G., Baret B., du Pree S.B., Bendahman M., Berbee E., van den Berg A.M., Bertin V., van Beveren V., Biagi S., Biagioni A., Bissinger M., Boumaaza J., Bourret S., Bouta M., Bouvet G., Bouwhuis M., Bozza C., Branzas H., Bruchner M., Bruijn R., Brunner J., Buis E., Buompane R., Busto J., Calvo D., Capone A., Celli S., Chabab M., Chau N., Cherubini S., Chiarella V., Chiarusi T., Circella M., Cocimano R., Coelho J.A.B., Coleiro A., Molla M.C., Colonges S., Coniglione R., Coyle P., Creusot A., Cuttone G., D'Onofrio A., Dallier R., De Palma M., Di Palma I., Diaz A.F., Diego-Tortosa D., Distefano C., Domi A., Dona R., Donzaud C., Dornic D., Dorr M., Durocher M., Eberl T., El Bojaddaini I., Eljarrari H., Elsaesser D., Enzenhofer A., Fermani P., Ferrara G., Filipovic M.D., Franco A., Fusco L.A., Gal T., Soto A.G., Garufi F., Gialanella L., Giorgio E., Gozzini S.R., Gracia R., Graf K., Grasso D., Gregoire T., Grella G., Guderian D., Guidi C., Hallmann S., Hamdaoui H., van Haren H., Heijboer A., Hekalo A., Hernandez-Rey J.J., Hofestadt J., Huang F., Illuminati G., James C.W., Jansweijer P., de Jong M., de Jong P., Kadler M., Kalaczynski P., Kalekin O., Katz U.F., Chowdhury N.R.K., van der Knaap F., Koffeman E.N., Kooijman P., Kouchner A., Kulikovskiy V., Lahmann R., Larosa G., Le Breton R., Leone F., Leonora E., Levi G., Lincetto M., Clark M.L., Lonardo A., Longhitano F., Lopez-Coto D., Maggi G., Manczak J., Mannheim K., Margiotta A., Marinelli A., Markou C., Martignac G., Martin L., Martinez-Mora J.A., Martini A., Marzaioli F., Mazzou S., Mele R., Melis K.W., Migliozzi P., Migneco E., Mijakowski P., Miranda L.S., Mollo C.M., Morganti M., Moser M., Moussa A., Muller R., Musumeci M., Nauta L., Navas S., Nicolau C.A., Nielsen C., O Fearraigh B., Organokov M., Orlando A., Panagopoulos V., Papalashvili G., Papaleo R., Pastore C., Pavalas G.E., Pellegrino C., Perrin-Terrin M., Piattelli P., Pieterse C., Pikounis K., Pisanti O., Poire C., Polydefki G., Popa V., Post M., Pradier T., Puhlhofer G., Pulvirenti S., Quinn L., Raffaelli F., Randazzo N., Rapicavoli A., Razzaque S., Real D., Reck S., Reubelt J., Riccobene G., Richer M., Rigalleau L., Rovelli A., Salvadori I., Samtleben D.F.E., Sanchez Losa A., Sanguineti M., Santangelo A., Santonocito D., Sapienza P., Schnabel J., Sciacca V., Seneca J., Sgura I., Shanidze R., Sharma A., Simeone F., Sinopoulou A., Spisso B., Spurio M., Stavropoulos D., Steijger J., Stellacci S.M., Strandberg B., Stransky D., Taiuti M., Tayalati Y., Tenllado E., Thakore T., Tingay S., Tzamariudaki E., Tzanetatos D., Van Elewyck V., Vannoye G., Versari F., Viola S., Vivolo D., de Wasseige G., Wilms J., Wojaczynski R., de Wolf E., Zaborov D., Zegarelli A., Zornoza J.D., Zuniga J., Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), and Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique)
Subjects: Computer science, data acquisition, Distributed computing, Data management, Astroparticle detector, Control unit, General Physics and Astronomy, Oceanografia, Oceanography, 01 natural sciences, High Energy Physics - Experiment, 010305 fluids & plasmas, Neutrino detector, High Energy Physics - Experiment (hep-ex), Software, Data acquisition, KM3NeT, data acquisition control, neutrino detector, astroparticle detector, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Neutrino detectors, modular, KM3NeT Data acquisition control Neutrino detector Astroparticle detector, [PHYS]Physics [physics], 4. Education, Control reconfiguration, Astroparticle detecto, 29.85.Ca, Hardware and Architecture, control system, Astrophysics - Instrumentation and Methods for Astrophysics, FOS: Physical sciences, programming, Failover, 07.05.Hd, Data acquisition control, 0103 physical sciences, Neutrins, 14. Life underwater, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, Instrumentation and Methods for Astrophysics (astro-ph.IM), Física [Àrees temàtiques de la UPC], Telescopis, business.industry, Provisioning, FISICA APLICADA, data management, business, Software architecture, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Telescopes
Abstract: The KM3NeT Collaboration runs a multi-site neutrino observatory in the Mediterranean Sea. Water Cherenkov particle detectors, deep in the sea and far off the coasts of France and Italy, are already taking data while incremental construction progresses. Data Acquisition Control software is operating off-shore detectors as well as testing and qualification stations for their components. The software, named Control Unit, is highly modular. It can undergo upgrades and reconfiguration with the acquisition running. Interplay with the central database of the Collaboration is obtained in a way that allows for data taking even if Internet links fail. In order to simplify the management of computing resources in the long term, and to cope with possible hardware failures of one or more computers, the KM3NeT Control Unit software features a custom dynamic resource provisioning and failover technology, which is especially important for ensuring continuity in case of rare transient events in multi-messenger, French National Research Agency (ANR) ANR-15-CE31-0020, Centre National de la Recherche Scientifique (CNRS), Commission Europeenne (FEDER fund), European Union (EU), Institut Universitaire de France (IUF), France, IdEx program, Univearths Labex program at Sorbonne Paris Cite, France ANR-10-LABX-0023 ANR-11-IDEX-000502, Paris Ile-de-France Region, France, Shota Rustaveli National Science Foundation of Georgia (SRNSFG), Georgia FR-18-1268, German Research Foundation (DFG), Greek Ministry of Development-GSRT, Istituto Nazionale di Fisica Nucleare (INFN), Ministero dell'Istruzione, dell'Universita e della Ricerca (MIUR), PRIN 2017 program Italy NAT-NET 2017W4HA7S, Ministry of Higher Education, Scientific Research and Professional Training, Morocco, Netherlands Organization for Scientific Research (NWO) Netherlands Government, National Science Center, Poland National Science Centre, Poland 2015/18/E/ST2/00758, National Authority for Scientific Research (ANCS), Romania, Ministerio de Ciencia, Innovacion, Investigacion y Universidades (MCIU), Spain, Programa Estatal de Generacion de Conocimiento (MCIU/FEDER) PGC2018-096663-B-C41 PGC2018-096663-A-C42 PGC2018-096663-B-C43 PGC2018-096663-BC44, Severo Ochoa Centre of Excellence, MultiDark Consolider (MCIU), Spain, Junta de Andalucía, Generalitat Valenciana, Spain: Grisolia GRISOLIA/2018/119, Generalitat Valenciana CIDEGENT/2018/034, La Caixa Foundation LCF/BQ/IN17/11620019, EU: MSC program, Spain 713673
Published: 2020

31. Health-related quality of life and rates of toxicity after high-dose-rate brachytherapy in combination with external beam radiation therapy for high-risk prostate cancer

Author: Silvia Selinski, Hui-Juan Huang-Tiel, Kathrin Bathe, Thorsten H. Ecke, Steffen Hallmann, Klaus Golka, Isabella Otto, and Stephan Koswig
Subjects: Male, Quality of life, medicine.medical_specialty, Urological Oncology, Urology, medicine.medical_treatment, Brachytherapy, 030232 urology & nephrology, lcsh:RC870-923, Risk Assessment, Cohort Studies, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Internal medicine, medicine, Humans, Adverse effect, Aged, Radiotherapy, business.industry, Prostatic Neoplasms, Cancer, Radiotherapy Dosage, Middle Aged, lcsh:Diseases of the genitourinary system. Urology, medicine.disease, humanities, Radiation therapy, 030220 oncology & carcinogenesis, Cohort, Original Article, International Prostate Symptom Score, Prostatic neoplasms, business
Abstract: PURPOSE: High-dose-rate brachytherapy (HDR-BT) with external beam radiation therapy (EBRT) is a common treatment option for locally advanced prostate cancer. Quality of life is an important factor when discussing therapy options for high-risk prostate cancer. This study evaluated adverse effects and health-related quality of life (HRQOL). MATERIALS AND METHODS: Ninety male patients (median age, 71 years; range, 50 to 79 years) with high-risk prostate cancer underwent HDR-BT after EBRT between December 2009 and January 2017 with a median follow-up of 43 months. A total of 57 patients (69.5%) answered the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life of Cancer Patients questionnaire (QLQ-C30; ver. 3.0), and 8 patients died during follow-up. In order to put the results of this study in context, we compared the results with reference data from the EORTC QLQ-C30 Scoring Manual. Correlations of prostate-specific antigen (PSA) values, International Prostate Symptom Score, and HRQOL measures were calculated. RESULTS: The study participants reported better physical functioning and better global health compared with the reference data, but worse social, role, and cognitive functioning. We found negative statistically significant correlations between the last-measured PSA value and social functioning (p>0.01), cognitive functioning, pain, and constipation (all p
Published: 2020

32. Constraining the contribution of Gamma-Ray Bursts to the high-energy diffuse neutrino flux with 10 years of ANTARES data

Author: J.D. Zornoza, U. Katz, F. Filippini, H. Brânzaş, Steven Tingay, Giuseppe Levi, Michel André, B. Strandberg, M. Perrin-Terrin, M. Anghinolfi, Michael Moser, J. Hößl, R. Cherkaoui El Moursli, Hervé Glotin, V. Van Elewyck, Dominique Lefèvre, Julien Aublin, G. Illuminati, P. de Jong, C. W. James, N.R. Khan-Chowdhury, Jutta Schnabel, M. Taiuti, Th. Stolarczyk, Silvia Celli, Alba Domi, Alessia Capone, A. Creusot, Emanuele Leonora, S. Sánchez Navas, N. Randazzo, J. Carr, S. Reck, C. Donzaud, Abdelilah Moussa, A. Trovato, D. Lopez-Coto, V. Popa, Thierry Pradier, B. Belhorma, G.E. Păvălaş, Mohamed Chabab, Steffen Hallmann, S. Viola, S.F. Biagi, B. O'Fearraigh, Massimiliano Lincetto, Thomas Eberl, M. Bissinger, A. Marinelli, T. N. Chau, R. Gozzini, F. Schüssler, Matthias Kadler, A. Sánchez-Losa, Robert Lahmann, M. Organokov, P. Coyle, R. Le Breton, R. Muller, O. Kalekin, Jörn Wilms, Kay Graf, Karel Melis, Daniele Vivolo, M.C. Bouwhuis, M. Jongen, Anne Deschamps, L. Nauta, Antoine Kouchner, C. Guidi, C. Distefano, D. F. E. Samtleben, B. Baret, Vladimir Kulikovskiy, C. Pellegrino, Damien Dornic, A. Zegarelli, M. de Jong, Matteo Sanguineti, A. Nuñez-Castiñeyra, Giovanna Ferrara, M. Circella, J. Manczak, J. Brunner, M. Colomer-Molla, E. Nezri, G. Maggi, G. Riccobene, B. Vallage, V. Bertin, P. Migliozzi, R. Bruijn, S. Loucatos, G. de Wasseige, I. Di Palma, Antonio F. Díaz, Maurizio Spurio, F. Huang, Arnauld Albert, A.J. Heijboer, Paolo Fermani, J. Zúñiga, Tommaso Chiarusi, N. E. l. Khayati, C. Poirè, P. Piattelli, J.A. Martínez-Mora, Alexis Coleiro, M. Marcelin, R. Coniglione, J. Hofestädt, L. Caramete, Jihad Boumaaza, Paolo Sapienza, M. Ardid, F. Versari, A. Enzenhöfer, Yann Hello, S. Mazzou, D. Drouhin, Gisela Anton, J.J. Hernández-Rey, Yahya Tayalati, S. Basa, L. Fusco, H. van Haren, M. Bouta, A. Ettahiri, Annarita Margiotta, Jose Busto, T. Thakore, I. Kreykenbohm, J-J. Aubert, Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Géoazur (GEOAZUR 7329), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Université Paris-Sud - Paris 11 (UP11), Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Informatique et Systèmes (LIS), Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Institut méditerranéen d'océanologie (MIO), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, ANTARES, ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Aix Marseille Université (AMU)-Centre National d'Études Spatiales [Toulouse] (CNES), Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Toulon (UTLN), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Clermont Auvergne (UCA)-Centre National de la Recherche Scientifique (CNRS), KM3NeT (IHEF, IoP, FNWI), IoP (FNWI), ATLAS (IHEF, IoP, FNWI), IHEF (IoP, FNWI), Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, Albert A., Andre M., Anghinolfi M., Anton G., Ardid M., Aubert J.-J., Aublin J., Baret B., Basa S., Belhorma B., Bertin V., Biagi S., Bissinger M., Boumaaza J., Bouta M., Bouwhuis M.C., Branzas H., Bruijn R., Brunner J., Busto J., Capone A., Caramete L., Carr J., Celli S., Chabab M., Chau T.N., Cherkaoui El Moursli R., Chiarusi T., Circella M., Coleiro A., Colomer-Molla M., Coniglione R., Coyle P., Creusot A., Diaz A.F., De Wasseige G., Deschamps A., Distefano C., Palma I.D., Domi A., Donzaud C., Dornic D., Drouhin D., Eberl T., Khayati N.E.L., Enzenhofer A., Ettahiri A., Fermani P., Ferrara G., Filippini F., Fusco L.A., Gay P., Glotin H., Gozzini R., Graf K., Guidi C., Hallmann S., Van Haren H., Heijboer A.J., Hello Y., Hernandez-Rey J.J., Hossl J., Hofestadt J., Huang F., Illuminati G., James C.W., De Jong M., De Jong P., Jongen M., Kadler M., Kalekin O., Katz U., Khan-Chowdhury N.R., Kouchner A., Kreykenbohm I., Kulikovskiy V., Lahmann R., Le Breton R., Lefevre D., Leonora E., Levi G., Lincetto M., Lopez-Coto D., Loucatos S., Maggi G., Manczak J., Marcelin M., Margiotta A., Marinelli A., Martinez-Mora J.A., Mazzou S., Melis K., Migliozzi P., Moser M., Moussa A., Muller R., Nauta L., Navas S., Nezri E., Nunez-Castineyra A., O'Fearraigh B., Organokov M., Pavalas G.E., Pellegrino C., Perrin-Terrin M., Piattelli P., Poire C., Popa V., Pradier T., Randazzo N., Reck S., Riccobene G., Sanchez-Losa A., Samtleben D.F.E., Sanguineti M., Sapienza P., Schnabel J., Schussler F., Spurio M., Stolarczyk T., Strandberg B., Taiuti M., Tayalati Y., Thakore T., Tingay S.J., Trovato A., Vallage B., Van Elewyck V., Versari F., Viola S., Vivolo D., Wilms J., Zegarelli A., Zornoza J.D., and Zuniga J.
Subjects: Astrofísica, Acceleration of particles, Flux, Astrophysics, 7. Clean energy, 01 natural sciences, neutrino: flux, IceCube, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), neutrino, Gamma rays bursts, Hadronic interactions, Raigs gamma, hal-03171355, transients: gamma-ray bursts, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], acceleration of particles, astroparticle physics, neutrinos, 010303 astronomy & astrophysics, acceleration of particle, High Energy Astrophysical Phenomena (astro-ph.HE), Physics, astro-ph.HE, astro-ph.IM, Energy, astroparticle physic, shock waves, Cosmology, Lorentz factor, Physique [physics]/Astrophysique [astro-ph], Neutrino detector, Neutrino astronomy, quality, stacking, gamma-ray bursts [Transients], symbols, Gamma-ray bursts, Neutrino, Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics, Central engines, Lorentz, Internal shocks, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, Neutrino fluxes, gamma ray: burst, Physique [physics]/Physique [physics], Transients, symbols.namesake, muon, 0103 physical sciences, Neutrins, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Neutrinos, Instrumentation and Methods for Astrophysics (astro-ph.IM), Cosmic rays, Neutrons, Astroparticle physics, neutrino muon, Muon, ANTARES, 010308 nuclear & particles physics, Gamma rays, Diffuse flux, Astronomy and Astrophysics, Astrophysical sources, redshift, Stars, Physique [physics]/Physique des Hautes Energies - Expérience [hep-ex], Redshift, Space and Planetary Science, FISICA APLICADA, Física::Astronomia i astrofísica [Àrees temàtiques de la UPC], High Energy Physics::Experiment, Gamma-ray burst, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Abstract: [EN] Addressing the origin of the astrophysical neutrino flux observed by IceCube is of paramount importance. Gamma-Ray Bursts (GRBs) are among the few astrophysical sources capable of achieving the required energy to contribute to such neutrino flux through p¿ interactions. In this work, ANTARES data have been used to search for upward going muon neutrinos in spatial and temporal coincidence with 784 GRBs occurred from 2007 to 2017. For each GRB, the expected neutrino flux has been calculated in the framework of the internal shock model and the impact of the lack of knowledge on the majority of source redshifts and on other intrinsic parameters of the emission mechanism has been quantified. It is found that the model parameters that set the radial distance where shock collisions occur have the largest impact on neutrino flux expectations. In particular, the bulk Lorentz factor of the source ejecta and the minimum variability time-scale are found to contribute significantly to the GRB-neutrino flux uncertainty. For the selected sources, ANTARES data have been analysed by maximizing the discovery probability of the stacking sample through an extended maximum-likelihood strategy. Since no neutrino event passed the quality cuts set by the optimization procedure, 90 per cent confidence level upper limits (with their uncertainty) on the total expected diffuse neutrino flux have been derived, according to the model. The GRB contribution to the observed diffuse astrophysical neutrino flux around 100 TeV is constrained to be less than 10 per cent., The authors acknowledge the financial support of the funding agencies: Centre National de la Recherche Scientifique (CNRS), Commissariata l'energie atomique et auxenergies alternatives (CEA), Commission Europeenne (FEDER fund and Marie Curie Program), Institut Universitaire de France (IUF), LabEx UnivEarthS (ANR-10-LABX-0023 and ANR-18-IDEX-0001), Region Ile-de-France (DIM-ACAV), Region Alsace (contrat CPER), Region Provence-Alpes-Cote d'Azur, Departement du Var and Ville de La Seyne-sur-Mer, France; Bundesministerium fur Bildung und Forschung (BMBF), Germany; Istituto Nazionale di Fisica Nucleare (INFN), Italy; Nederlandse organisatie voor Wetenschappelijk Onderzoek (NWO), the Netherlands; Council of the President of the Russian Federation for young scientists and leading scientific schools supporting grants, Russia; Executive Unit for Financing Higher Education, Research, Development and Innovation (UEFISCDI), Romania; Ministerio de Ciencia, Innovacion, Investigacion y Universidades (MCIU): Programa Estatal de Generacion de Conocimiento (refs. PGC2018-096663-B-C41, -A-C42, -B-C43, -B-C44) (MCIU/FEDER), Severo Ochoa Centre of Excellence and MultiDark Consolider (MCIU), Junta de Andalucia (ref. SOMM17/6104/UGR and A-FQM-053-UGR18), Generalitat Valenciana: Grisolia (ref. GRISOLIA/2018/119), Spain; Ministry of Higher Education, Scientific Research and Professional Training, Morocco. We also acknowledge the technical support of Ifremer, AIM and Foselev Marine for the sea operation and the CC-IN2P3 for the computing facilities.
Published: 2020

33. Deep-sea deployment of the KM3NeT neutrino telescope detection units by self-unrolling

Author: Jose Busto, T. Hillebrand, Matthias Kadler, Piotr Kalaczyński, F. Garufi, T. Thakore, E. Tenllado, B. Baret, Joao A B Coelho, A. Cosquer, Mancia Anguita, L. Maderer, E. G. Anassontzis, Dominik Elsaesser, Y. Gatelet, Gennaro Miele, Alba Domi, D. Calvo, D. Lopez-Coto, Ornella Leonardi, V. Popa, Rosanna Cocimano, M. Mongelli, Emanuele Leonora, L. Nauta, Steffen Hallmann, Jutta Schnabel, Lucio Gialanella, J.D. Zornoza, S. Reck, E. Berbee, G. Pühlhofer, R. Wojaczyński, G. Ferrara, Steven Tingay, Robert Lahmann, Domenico Santonocito, Michael Moser, Giuseppina Larosa, R. Le Breton, R. Gracia, Matteo Sanguineti, F. Versari, A. Enzenhöfer, Mohamed Chabab, Natalia Zywucka, A. Marinelli, O. Kalekin, M. Billault, Alessia Capone, A. Creusot, M. Lindsey Clark, A. Sánchez Losa, R. Donà, H. Hamdaoui, O. Rabyang, P.M. Kooijman, M. De Palma, Tommaso Chiarusi, S. Alves Garre, A. W. Chen, Lilian Martin, Daniele Vivolo, M.C. Bouwhuis, Paolo Fermani, Matthias Bissinger, R. Bakker, G. Riccobene, Riccardo Papaleo, A. Grmek, S. Basegmez du Pree, Miroslav Filipovic, A. Martini, M. Ardid, Patrick Lamare, Daniele Zito, G. Androulakis, P. Migliozzi, Dídac Diego-Tortosa, S. Viola, Arnauld Albert, N. Chau, F. Huang, Soebur Razzaque, Sara Pulvirenti, C. Pellegrino, M. Bouta, C. Pastore, R. Coniglione, Damien Dornic, Jos Steijger, S. Colonges, S.F. Biagi, E. A. De Wolf, Paolo Sapienza, G. C. Barbarino, D. Muñoz Pérez, Silvio Cherubini, M. Circella, M. Bendahman, C. Bagatelas, S. Mazzou, Gisela Anton, P. Mijakowski, Annarita Margiotta, D. Tzanetatos, Giorgi Kistauri, Cristiano Bozza, Nicole Geisselbrecht, V. Bertin, D. Drouhin, Els Koffeman, Francesco Leone, J. Hofestädt, T. Gal, F. Filippini, Fabio Marzaioli, J. Zúñiga, F. Raffaelli, L. Caillat, Markus Boettcher, V. Espinosa, Richard Dallier, D. Guderian, J.A. Martínez-Mora, Alexis Coleiro, C. Distefano, Dario Grasso, Fabrizio Ameli, D. F. E. Samtleben, A. Hekalo, J. Schumann, M. de Jong, M. Morganti, Jihad Boumaaza, Emidio Giorgio, P. Coyle, I. Corredoira, I. Sgura, Antonio D'Onofrio, E. Tzamariudaki, Kay Graf, Karel Melis, Giacomo Cuttone, T. Lipreau, M. Taiuti, Vitaliano Chiarella, P. de Jong, D. Stavropoulos, C. Poirè, Michel André, Angelo Orlando, P. Piattelli, D. van Eijk, Carlos Maximiliano Mollo, Zineb Aly, Jörn Wilms, G. Cacopardo, Alin Ilioni, M. Perrin-Terrin, A. Rovelli, Barbara Caiffi, Abdelilah Moussa, A.M. van den Berg, V. Van Elewyck, J. Brunner, Carlo Alessandro Nicolau, F. van der Knaap, Luigi Antonio Fusco, Thierry Pradier, S. Rivoire, M. Laan, C. Markou, J. Seneca, U. Katz, Diego Real, S. R. Gozzini, C. D'Amato, Fabio Longhitano, H. Brânzaş, J. van Heerwaarden, C. Donzaud, Massimiliano Lincetto, Ofelia Pisanti, V. Carretero, M. Colomer Molla, Mario Musumeci, Michael Kreter, N. Randazzo, M. Anghinolfi, Maurizio Spurio, A.J. Heijboer, E. Migneco, I. El Bojaddaini, B. Spisso, M. Richer, S. Henry, L. S. Miranda, H. van Haren, Andrea Santangelo, A. Sinopoulou, Antoine Kouchner, Julien Aublin, G. Illuminati, A. Zegarelli, Sandra Zavatarelli, C. Pieterse, T. van Eeden, C. W. James, Mitchell O'Sullivan, Raffaele Buompane, Alice Paun, I. Di Palma, Antonio F. Díaz, Francesco Simeone, L. Gostiaux, Rezo Shanidze, M. Dörr, Paolo Castaldi, G. Vasileiadis, F. Salesa Greus, R. Bruijn, Silvia Celli, Thomas Eberl, A. Sharma, R. Muller, Bouke Jisse Jung, C. Guidi, K. Pikounis, Vladimir Kulikovskiy, J. Manczak, E. Buis, J.J. Hernández-Rey, Yahya Tayalati, Sebastiano Aiello, G. Grella, O. Gabella, Giuseppe Levi, G. Papalashvili, D. Tézier, G. de Wasseige, S. Sánchez Navas, Jerome Laurence, Karl Mannheim, Ahmed Eddyamoui, S. Mastroianni, M. Organokov, B. Ó Fearraigh, N. R. Khan Chowdhury, W. Idrissi Ibnsalih, Simona Maria Stellacci, G.E. Păvălaş, A. Garcia Soto, J. Palacios González, AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Mecanique des Fluides et d'Acoustique (LMFA), École Centrale de Lyon (ECL), Université de Lyon-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), KM3NeT, ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018), Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, Institut Pluridisciplinaire Hubert Curien (IPHC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Groupe de Recherche en Physique des Hautes Energies (GRPHE), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut Universitaire de Technologie de Colmar, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Laboratoire de physique subatomique et des technologies associées (SUBATECH), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Laboratoire Univers et Particules de Montpellier (LUPM), Université Montpellier 2 - Sciences et Techniques (UM2)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Aiello S., Albert A., Alves Garre S., Aly Z., Ameli F., Anassontzis E.G., Andre M., Androulakis G., Anghinolfi M., Anguita M., Anton G., Ardid M., Aublin J., Bagatelas C., Bakker R., Barbarino G., Baret B., Basegmez du Pree S., Bendahman M., Berbee E., van den Berg A.M., Bertin V., Biagi S., Billault M., Bissinger M., Boettcher M., Boumaaza J., Bouta M., Bouwhuis M., Bozza C., Branzas H., Bruijn R., Brunner J., Buis E., Buompane R., Busto J., Cacopardo G., Caiffi B., Caillat L., Calvo D., Capone A., Carretero V., Castaldi P., Celli S., Chabab M., Chau N., Chen A., Cherubini S., Chiarella V., Chiarusi T., Circella M., Cocimano R., Coelho J.A.B., Coleiro A., Colomer Molla M., Colonges S., Coniglione R., Corredoira I., Cosquer A., Coyle P., Creusot A., Cuttone G., D'Amato C., D'Onofrio A., Dallier R., de Palma M., Di Palma I., Diaz A.F., Diego-Tortosa D., Distefano C., Domi A., Dona R., Donzaud C., Dornic D., Dorr M., Drouhin D., Eberl T., Eddyamoui A., van Eeden T., van Eijk D., El Bojaddaini I., Elsaesser D., Enzenhofer A., Espinosa V., Fermani P., Ferrara G., Filipovic M.D., Filippini F., Fusco L.A., Gabella O., Gal T., Garcia Soto A., Garufi F., Gatelet Y., Geisselbrecht N., Gialanella L., Giorgio E., Gostiaux L., Gozzini S.R., Gracia R., Graf K., Grasso D., Grella G., Grmek A., Guderian D., Guidi C., Hallmann S., Hamdaoui H., van Haren H., van Heerwaarden J., Heijboer A., Hekalo A., Henry S., Hernandez-Rey J.J., Hillebrand T., Hofestadt J., Huang F., Idrissi Ibnsalih W., Ilioni A., Illuminati G., James C.W., de Jong M., de Jong P., Jung B.J., Kadler M., Kalaczynski P., Kalekin O., Katz U.F., Khan Chowdhury N.R., Kistauri G., van der Knaap F., Koffeman E.N., Kooijman P., Kouchner A., Kreter M., Kulikovskiy V., Laan M., Lahmann R., Lamare P., Larosa G., Laurence J., Le Breton R., Leonardi O., Leone F., Leonora E., Levi G., Lincetto M., Lindsey Clark M., Lipreau T., Longhitano F., Lopez-Coto D., Maderer L., Manczak J., Mannheim K., Margiotta A., Marinelli A., Markou C., Martin L., Martinez-Mora J.A., Martini A., Marzaioli F., Mastroianni S., Mazzou S., Melis K.W., Miele G., Migliozzi P., Migneco E., Mijakowski P., Miranda L.S., Mollo C.M., Mongelli M., Morganti M., Moser M., Moussa A., Muller R., Munoz Perez D., Musumeci M., Nauta L., Navas S., Nicolau C.A., O Fearraigh B., O'Sullivan M., Organokov M., Orlando A., Palacios Gonzalez J., Papalashvili G., Papaleo R., Pastore C., Paun A.M., Pavalas G.E., Pellegrino C., Perrin-Terrin M., Piattelli P., Pieterse C., Pikounis K., Pisanti O., Poire C., Popa V., Pradier T., Puhlhofer G., Pulvirenti S., Rabyang O., Raffaelli F., Randazzo N., Razzaque S., Real D., Reck S., Riccobene G., Richer M., Rivoire S., Rovelli A., Salesa Greus F., Samtleben D.F.E., Sanchez Losa A., Sanguineti M., Santangelo A., Santonocito D., Sapienza P., Schnabel J., Schumann J., Seneca J., Sgura I., Shanidze R., Sharma A., Simeone F., Sinopoulou A., Spisso B., Spurio M., Stavropoulos D., Steijger J., Stellacci S.M., Taiuti M., Tayalati Y., Tenllado E., Tezier D., Thakore T., Tingay S., Tzamariudaki E., Tzanetatos D., van Elewyck V., Vasileiadis G., Versari F., Viola S., Vivolo D., de Wasseige G., Wilms J., Wojaczynski R., de Wolf E., Zavatarelli S., Zegarelli A., Zito D., Zornoza J.D., Zuniga J., Zywucka N., Aiello, S., Albert, A., Alves Garre, S., Aly, Z., Ameli, F., Anassontzis, E. G., Andre, M., Androulakis, G., Anghinolfi, M., Anguita, M., Anton, G., Ardid, M., Aublin, J., Bagatelas, C., Bakker, R., Barbarino, G., Baret, B., Basegmez du Pree, S., Bendahman, M., Berbee, E., van den Berg, A. M., Bertin, V., Biagi, S., Billault, M., Bissinger, M., Boettcher, M., Boumaaza, J., Bouta, M., Bouwhuis, M., Bozza, C., Branzas, H., Bruijn, R., Brunner, J., Buis, E., Buompane, R., Busto, J., Cacopardo, G., Caiffi, B., Caillat, L., Calvo, D., Capone, A., Carretero, V., Castaldi, P., Celli, S., Chabab, M., Chau, N., Chen, A., Cherubini, S., Chiarella, V., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Colomer Molla, M., Colonges, S., Coniglione, R., Corredoira, I., Cosquer, A., Coyle, P., Creusot, A., Cuttone, G., D'Amato, C., D'Onofrio, A., Dallier, R., de Palma, M., Di Palma, I., Diaz, A. F., Diego-Tortosa, D., Distefano, C., Domi, A., Dona, R., Donzaud, C., Dornic, D., Dorr, M., Drouhin, D., Eberl, T., Eddyamoui, A., van Eeden, T., van Eijk, D., El Bojaddaini, I., Elsaesser, D., Enzenhofer, A., Espinosa, V., Fermani, P., Ferrara, G., Filipovic, M. D., Filippini, F., Fusco, L. A., Gabella, O., Gal, T., Garcia Soto, A., Garufi, F., Gatelet, Y., Geisselbrecht, N., Gialanella, L., Giorgio, E., Gostiaux, L., Gozzini, S. R., Gracia, R., Graf, K., Grasso, D., Grella, G., Grmek, A., Guderian, D., Guidi, C., Hallmann, S., Hamdaoui, H., van Haren, H., van Heerwaarden, J., Heijboer, A., Hekalo, A., Henry, S., Hernandez-Rey, J. J., Hillebrand, T., Hofestadt, J., Huang, F., Idrissi Ibnsalih, W., Ilioni, A., Illuminati, G., James, C. W., de Jong, M., de Jong, P., Jung, B. J., Kadler, M., Kalaczynski, P., Kalekin, O., Katz, U. F., Khan Chowdhury, N. R., Kistauri, G., van der Knaap, F., Koffeman, E. N., Kooijman, P., Kouchner, A., Kreter, M., Kulikovskiy, V., Laan, M., Lahmann, R., Lamare, P., Larosa, G., Laurence, J., Le Breton, R., Leonardi, O., Leone, F., Leonora, E., Levi, G., Lincetto, M., Lindsey Clark, M., Lipreau, T., Longhitano, F., Lopez-Coto, D., Maderer, L., Manczak, J., Mannheim, K., Margiotta, A., Marinelli, A., Markou, C., Martin, L., Martinez-Mora, J. A., Martini, A., Marzaioli, F., Mastroianni, S., Mazzou, S., Melis, K. W., Miele, G., Migliozzi, P., Migneco, E., Mijakowski, P., Miranda, L. S., Mollo, C. M., Mongelli, M., Morganti, M., Moser, M., Moussa, A., Muller, R., Munoz Perez, D., Musumeci, M., Nauta, L., Navas, S., Nicolau, C. A., O Fearraigh, B., O'Sullivan, M., Organokov, M., Orlando, A., Palacios Gonzalez, J., Papalashvili, G., Papaleo, R., Pastore, C., Paun, A. M., Pavalas, G. E., Pellegrino, C., Perrin-Terrin, M., Piattelli, P., Pieterse, C., Pikounis, K., Pisanti, O., Poire, C., Popa, V., Pradier, T., Puhlhofer, G., Pulvirenti, S., Rabyang, O., Raffaelli, F., Randazzo, N., Razzaque, S., Real, D., Reck, S., Riccobene, G., Richer, M., Rivoire, S., Rovelli, A., Salesa Greus, F., Samtleben, D. F. E., Sanchez Losa, A., Sanguineti, M., Santangelo, A., Santonocito, D., Sapienza, P., Schnabel, J., Schumann, J., Seneca, J., Sgura, I., Shanidze, R., Sharma, A., Simeone, F., Sinopoulou, A., Spisso, B., Spurio, M., Stavropoulos, D., Steijger, J., Stellacci, S. M., Taiuti, M., Tayalati, Y., Tenllado, E., Tezier, D., Thakore, T., Tingay, S., Tzamariudaki, E., Tzanetatos, D., van Elewyck, V., Vasileiadis, G., Versari, F., Viola, S., Vivolo, D., de Wasseige, G., Wilms, J., Wojaczynski, R., de Wolf, E., Zavatarelli, S., Zegarelli, A., Zito, D., Zornoza, J. D., Zuniga, J., Zywucka, N., Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), KM3NeT (IHEF, IoP, FNWI), ATLAS (IHEF, IoP, FNWI), IoP (FNWI), and Research unit Astroparticle Physics
Subjects: Astrofísica, Overall mechanics design (support structures and materials, vibration analysis etc), Dispositius optoelectrònics, Física::Física de partícules [Àrees temàtiques de la UPC], cherenkov, Astrophysics, 01 natural sciences, String (physics), 030218 nuclear medicine & medical imaging, 0302 clinical medicine, Underwater, Special cables, Instrumentation, KM3NeT, Mathematical Physics, glass, 4. Education, charged particle, neutrino: detector, Neutrino detector, Cherenkov counters, Neutrino, Astrophysics - Instrumentation and Methods for Astrophysics, Optoelectrònica, Geology, Marine engineering, Cherenkov detector, sea, Cherenkov detectors, Manufacturing, tube, FOS: Physical sciences, Baikal, Physique [physics]/Physique [physics], Optoelectronic devides, 03 medical and health sciences, 0103 physical sciences, surface, 14. Life underwater, Neutrins, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Optoelectronics, detector: optical, copper: wire, Instrumentation and Methods for Astrophysics (astro-ph.IM), Cherenkov radiation, Detectors òptics, Optical detectors, ANTARES, Telescopis, 010308 nuclear & particles physics, Mooring, radiation: Cherenkov, vibration analysis etc), Overall mechanics design (support structures and materials, monitoring, astro-ph.IM, FISICA APLICADA, string, sphere, Telescopes
Abstract: KM3NeT is a research infrastructure being installed in the deep Mediterranean Sea. It will house a neutrino telescope comprising hundreds of networked moorings — detection units or strings — equipped with optical instrumentation to detect the Cherenkov radiation generated by charged particles from neutrino-induced collisions in its vicinity. In comparison to moorings typically used for oceanography, several key features of the KM3NeT string are different: the instrumentation is contained in transparent and thus unprotected glass spheres; two thin Dyneema® ropes are used as strength members; and a thin delicate backbone tube with fibre-optics and copper wires for data and power transmission, respectively, runs along the full length of the mooring. Also, compared to other neutrino telescopes such as ANTARES in the Mediterranean Sea and GVD in Lake Baikal, the KM3NeT strings are more slender to minimise the amount of material used for support of the optical sensors. Moreover, the rate of deploying a large number of strings in a period of a few years is unprecedented. For all these reasons, for the installation of the KM3NeT strings, a custom-made, fast deployment method was designed. Despite the length of several hundreds of metres, the slim design of the string allows it to be compacted into a small, re-usable spherical launching vehicle instead of deploying the mooring weight down from a surface vessel. After being lowered to the seafloor, the string unfurls to its full length with the buoyant launching vehicle rolling along the two ropes. The design of the vehicle, the loading with a string, and its underwater self-unrolling are detailed in this paper., French National Research Agency (ANR) ANR-15-CE31-0020, Centre National de la Recherche Scientifique (CNRS), European Union (EU), Institut Universitaire de France (IUF), LabEx UnivEarthS ANR-10-LABX-0023 ANR-18-IDEX-0001, Paris Ile-de-France Region, France, Shota Rustaveli National Science Foundation of Georgia (SRNSFG), Georgia FR-18-1268, German Research Foundation (DFG), Greek Ministry of Development-GSRT, Istituto Nazionale di Fisica Nucleare (INFN), Ministero dell'Universita e della Ricerca (MUR), PRIN Italy NAT-NET 2017W4HA7S, Ministry of Higher Education, Scientific Research and Professional Training, Morocco, Netherlands Organization for Scientific Research (NWO) Netherlands Government, National Science Center, Poland National Science Centre, Poland 2015/18/E/ST2/00758, National Authority for Scientific Research (ANCS), Romania, Ministerio de Ciencia, Innovación, Investigación y Universidades (MCIU): Programa Estatal de Generación de Conocimiento (MCIU/FEDER) PGC2018-096663-B-C41 PGC2018-096663-B-A-C42 PGC2018-096663-B-BC43 PGC2018-096663-B-B-C44, Severo Ochoa Centre of Excellence and MultiDark Consolider (MCIU), Junta de Andalucía SOMM17/6104/UGR, Generalitat Valenciana GRISOLIA/2018/119 CIDEGENT/2018/034, La Caixa Foundation LCF/BQ/IN17/11620019, EU: MSC program, Spain 713673
Published: 2020

34. Event reconstruction for KM3NeT/ORCA using convolutional neural networks

Author: S. Mastroianni, Alessia Capone, P.M. Kooijman, M. Organokov, B. Ó Fearraigh, M. Taiuti, N. R. Khan Chowdhury, W. Idrissi Ibnsalih, Simona Maria Stellacci, Carlos Maximiliano Mollo, Daniele Vivolo, O. Gabella, Giuseppe Levi, J. Seneca, Jos Steijger, S. Alves Garre, A. W. Chen, Luigi Antonio Fusco, Thierry Pradier, S. Rivoire, V. Espinosa Roselló, G. Pühlhofer, A. Enzenhöfer, Massimiliano Lincetto, A. Martini, M. Bendahman, Piotr Kalaczyński, Bruny Baret, C. Bagatelas, G. Papalashvili, Karl Mannheim, Ahmed Eddyamoui, Alessandro Lonardo, A. Rapicavoli, K. Pikounis, R. Bruijn, Diego Real, I. El Bojaddaini, J.J. Hernández-Rey, Yahya Tayalati, G. C. Barbarino, C. Pellegrino, Silvio Cherubini, Giuseppina Larosa, L. S. Miranda, Matthias Kadler, Ofelia Pisanti, F. Garufi, M. Lindsey Clark, S. Mazzou, Gisela Anton, Andrea Santangelo, R. Le Breton, Vladimir Kulikovskiy, I. Sgura, P. de Jong, D. Stavropoulos, Angelo Orlando, Francesco Leone, G.E. Păvălaş, E. Tenllado, J. Manczak, Soebur Razzaque, A. Garcia Soto, Natalia Zywucka, A. Rovelli, Ornella Leonardi, E. Tzamariudaki, Giulia Illuminati, M. Bouta, S. Basegmez du Pree, Miroslav Filipovic, Abdelilah Moussa, E. Buis, R. Muller, F. Filippini, E. Berbee, P. Mijakowski, S. R. Gozzini, Michael Kreter, Zineb Aly, Bouke Jisse Jung, N. Geißelbrecht, M. De Palma, Sebastiano Aiello, Nhan Chau, Annarita Margiotta, Thomas Lipreau, T. Gal, M. Morganti, M. Ardid, Robert Lahmann, Doriane Drouhin, M. de Jong, M. Perrin-Terrin, C. Distefano, Carlo Alessandro Nicolau, D. van Eijk, Richard Dallier, Michel André, G. Grella, D. F. E. Samtleben, A. Hekalo, Paolo Fermani, D. Zaborov, C. Guidi, T. Thakore, O. Kalekin, R. Donà, Antoine Kouchner, Dídac Diego-Tortosa, S. Sánchez Navas, Daniele Zito, P. Coyle, Giacomo Cuttone, G. de Wasseige, A.M. van den Berg, V. Van Elewyck, S. Viola, A. Zegarelli, M. Colomer Molla, Mancia Anguita, O. Rabyang, Silvia Celli, Sara Pulvirenti, Raffaele Buompane, Rosanna Cocimano, M. Post, I. Di Palma, F. Versari, Vitaliano Chiarella, V. Bertin, S.F. Biagi, Thomas Eberl, M. Bissinger, Riccardo Papaleo, P. Migliozzi, Tommaso Chiarusi, A. Sharma, E. A. De Wolf, G. Androulakis, C. Pastore, H. van Haren, Corinne Donzaud, Fabio Marzaioli, R. Coniglione, F. Raffaelli, A. Sinopoulou, Fabio Longhitano, J. Hofestädt, Jihad Boumaaza, D. Tzanetatos, Giorgi Kistauri, Cristiano Bozza, L. Martin, C. Poirè, P. Piattelli, Jutta Schnabel, S. Reck, L. Nauta, Sandra Zavatarelli, Matteo Sanguineti, G. Vannoye, G. Riccobene, D. Dornic, Y. Gatelet, T. van Eeden, D. Guderian, H. Hamdaoui, Kay Graf, Karel Melis, M. Circella, Andrea Biagioni, Arnauld Albert, Barbara Caiffi, H. Brânzaş, R. Wojaczyński, G. Ferrara, Mario Musumeci, N. Randazzo, F. van der Knaap, C. Markou, R. Gracia, J. Brunner, Emanuele Leonora, F. Huang, Mohamed Chabab, Antonio D'Onofrio, L. Maderer, Jörn Wilms, U. Katz, Els Koffeman, M. Anghinolfi, J. Busto, Markus Boettcher, E. Migneco, B. Spisso, M. Richer, J. A. B. Coelho, V. Carretero, Paolo Sapienza, Lucio Gialanella, J.D. Zornoza, C. Pieterse, C. W. James, Alice Paun, Paolo Castaldi, G. Vasileiadis, F. Salesa Greus, Steven Tingay, A. Marinelli, A. Sánchez Losa, Antonio F. Díaz, Francesco Simeone, M. Dörr, Domenico Santonocito, M.C. Bouwhuis, Michael Moser, Alba Domi, D. Calvo, J. Zúñiga, J.A. Martínez-Mora, Alexis Coleiro, Dario Grasso, Fabrizio Ameli, Emidio Giorgio, D. Lopez-Coto, V. Popa, Steffen Hallmann, Dominik Elsaesser, A. Creusot, Gennaro Miele, Rezo Shanidze, Julien Aublin, Maurizio Spurio, A.J. Heijboer, Aiello, S., Albert, A., Garre, S. A., Aly, Z., Ameli, F., Andre, M., Androulakis, G., Anghinolfi, M., Anguita, M., Anton, G., Ardid, M., Aublin, J., Bagatelas, C., Barbarino, G., Baret, B., du Pree, S. B., Bendahman, M., Berbee, E., van den Berg, A. M., Bertin, V., Biagi, S., Biagioni, A., Bissinger, M., Boettcher, M., Boumaaza, J., Bouta, M., Bouwhuis, M., Bozza, C., Branzas, H., Bruijn, R., Brunner, J., Buis, E., Buompane, R., Busto, J., Caiffi, B., Calvo, D., Capone, A., Carretero, V., Castaldi, P., Celli, S., Chabab, M., Chau, N., Chen, A., Cherubini, S., Chiarella, V., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Molla, M. C., Coniglione, R., Coyle, P., Creusot, A., Cuttone, G., D'Onofrio, A., Dallier, R., de Palma, M., Di Palma, I., Diaz, A. F., Diego-Tortosa, D., Distefano, C., Domi, A., Dona, R., Donzaud, C., Dornic, D., Dorr, M., Drouhin, D., Eberl, T., Eddyamoui, A., van Eeden, T., van Eijk, D., El Bojaddaini, I., Elsaesser, D., Enzenhofer, A., Rosello, V. E., Fermani, P., Ferrara, G., Filipovic, M. D., Filippini, F., Fusco, L. A., Gabella, O., Gal, T., Soto, A. G., Garufi, F., Gatelet, Y., Geisselbrecht, N., Gialanella, L., Giorgio, E., Gozzini, S. R., Gracia, R., Graf, K., Grasso, D., Grella, G., Guderian, D., Guidi, C., Hallmann, S., Hamdaoui, H., van Haren, H., Heijboer, A., Hekalo, A., Hernandez-Rey, J. J., Hofestadt, J., Huang, F., Ibnsalih, W. I., Illuminati, G., James, C. W., de Jong, M., de Jong, P., Jung, B. J., Kadler, M., Kalaczynski, P., Kalekin, O., Katz, U. F., Chowdhury, N. R. K., Kistauri, G., van der Knaap, F., Koffeman, E. N., Kooijman, P., Kouchner, A., Kreter, M., Kulikovskiy, V., Lahmann, R., Larosa, G., Le Breton, R., Leonardi, O., Leone, F., Leonora, E., Levi, G., Lincetto, M., Clark, M. L., Lipreau, T., Lonardo, A., Longhitano, F., Lopez-Coto, D., Maderer, L., Manczak, J., Mannheim, K., Margiotta, A., Marinelli, A., Markou, C., Martin, L., Martinez-Mora, J. A., Martini, A., Marzaioli, F., Mastroianni, S., Mazzou, S., Melis, K. W., Miele, G., Migliozzi, P., Migneco, E., Mijakowski, P., Miranda, L. S., Mollo, C. M., Morganti, M., Moser, M., Moussa, A., Muller, R., Musumeci, M., Nauta, L., Navas, S., Nicolau, C. A., Fearraigh, B. O., Organokov, M., Orlando, A., Papalashvili, G., Papaleo, R., Pastore, C., Paun, A. M., Pavalas, G. E., Pellegrino, C., Perrin-Terrin, M., Piattelli, P., Pieterse, C., Pikounis, K., Pisanti, O., Poire, C., Popa, V., Post, M., Pradier, T., Puhlhofer, G., Pulvirenti, S., Rabyang, O., Raffaelli, F., Randazzo, N., Rapicavoli, A., Razzaque, S., Real, D., Reck, S., Riccobene, G., Richer, M., Rivoire, S., Rovelli, A., Greus, F. S., Samtleben, D. F. E., Losa, A. S., Sanguineti, M., Santangelo, A., Santonocito, D., Sapienza, P., Schnabel, J., Seneca, J., Sgura, I., Shanidze, R., Sharma, A., Simeone, F., Sinopoulou, A., Spisso, B., Spurio, M., Stavropoulos, D., Steijger, J., Stellacci, S. M., Taiuti, M., Tayalati, Y., Tenllado, E., Thakore, T., Tingay, S., Tzamariudaki, E., Tzanetatos, D., van Elewyck, V., Vannoye, G., Vasileiadis, G., Versari, F., Viola, S., Vivolo, D., de Wasseige, G., Wilms, J., Wojaczynski, R., de Wolf, E., Zaborov, D., Zavatarelli, S., Zegarelli, A., Zito, D., Zornoza, J. D., Zuniga, J., Zywucka, N., Institut Pluridisciplinaire Hubert Curien (IPHC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Groupe de Recherche en Physique des Hautes Energies (GRPHE), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut Universitaire de Technologie de Colmar, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Laboratoire de physique subatomique et des technologies associées (SUBATECH), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Laboratoire Univers et Particules de Montpellier (LUPM), Université Montpellier 2 - Sciences et Techniques (UM2)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), KM3NeT, Garre, S. Alve, Pree, S. Basegmez du, Brânzaş, H., Molla, M. Colomer, Palma, M. De, Palma, I. Di, Díaz, A. F., Donà, R., Dörr, M., Eeden, T. van, Eijk, D. van, Bojaddaini, I. El, Enzenhöfer, A., Roselló, V. Espinosa, Filipović, M. D., Soto, A. Garcia, Geißelbrecht, N., Haren, H. van, Hernández-Rey, J. J., Hofestädt, J., Ibnsalih, W. Idrissi, Kalaczyński, P., Chowdhury, N. R Khan, Knaap, F. van der, Breton, R. Le, Clark, M. Lindsey, Mańczak, J., Martínez-Mora, J. A., Ó Fearraigh, B., Păun, A. M., Păvălaş, G. E., Poirè, C., Pühlhofer, G., Greus, F. Salesa, Sánchez Losa, A., Elewyck, V. Van, Wojaczyński, R., Zúñiga, J., KM3NeT (IHEF, IoP, FNWI), ATLAS (IHEF, IoP, FNWI), IoP (FNWI), 24420530 - Böttcher, Markus, 33379009 - Kreter, Michael, 34208968 - Zywucka-Hejzner, Natalia, Research unit Astroparticle Physics, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-IUT de Colmar, Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018), van den Berg, A.M., Coelho, J.A.B., Díaz, A.F., Fusco, L.A., Gozzini, S.R., Hernández-Rey, J.J., James, C.W., Jung, B.J., Katz, U.F., Chowdhury, N.R Khan, Koffeman, E.N., Martínez-Mora, J.A., Melis, K.W., Miranda, L.S., Mollo, C.M., Nicolau, C.A., Păvălaş, G.E., Samtleben, D.F.E., Stellacci, S.M., Zornoza, J.D., Centre Tecnològic de Vilanova i la Geltrú, and Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques
Subjects: Astrofísica, Physics - Instrumentation and Detectors, Computer science, Physics::Instrumentation and Detectors, Física::Física de partícules [Àrees temàtiques de la UPC], Optical instruments, Astrophysics, 01 natural sciences, Convolutional neural network, High Energy Physics - Experiment, 030218 nuclear medicine & medical imaging, Neutrino detector, High Energy Physics - Experiment (hep-ex), 0302 clinical medicine, neutrino: atmosphere, Neurociències, Neutrino detectors, neutrino: mass, Instrumentation, KM3NeT, Mathematical Physics, neutrino: interaction, Event reconstruction, photomultiplier, Artificial neural network, spatial distribution, 4. Education, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Instrumentation and Detectors (physics.ins-det), charged particle, neutrino: detector, vertex: primary, Neutrino, Astrophysics - Instrumentation and Methods for Astrophysics, astro-ph.IM, Algorithm, performance, Cherenkov detector, neural network, Cherenkov counter: water, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, 03 medical and health sciences, 0103 physical sciences, Neutrins, 14. Life underwater, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Instrumentation and Methods for Astrophysics (astro-ph.IM), Cherenkov radiation, Telescopis, 010308 nuclear & particles physics, Large detector systems for particle and astroparticle physics, background, Cherenkov detectors, Neurosciences, radiation: Cherenkov, Physique [physics]/Physique des Hautes Energies - Expérience [hep-ex], FISICA APLICADA, network, Large detector systems for particle and astroparticle physic, High Energy Physics::Experiment, Performance of High Energy Physics Detectors, hal-03178773, Òptica -- Aparells i instruments, Telescopes
Abstract: The authors acknowledge the financial support of the funding agencies: Agence Nationale de la Recherche (contract ANR-15-CE31-0020), Centre National de la Recherche Scientifique (CNRS), Commission Europeenne (FEDER fund and Marie Curie Program), Institut Universitaire de France (IUF), LabEx UnivEarthS (ANR-10-LABX-0023 and ANR-18-IDEX-0001), Paris Ile-de-France Region, France; Shota Rustaveli National Science Foundation of Georgia (SRNSFG, FR-18-1268), Georgia; Deutsche Forschungsgemeinschaft (DFG), Germany; The General Secretariat of Research and Technology (GSRT), Greece; Istituto Nazionale di Fisica Nucleare (INFN), Ministero dell'Universita e della Ricerca (MUR), PRIN 2017 program (Grant NAT-NET 2017W4HA7S) Italy; Ministry of Higher Education, Scientific Research and Professional Training, Morocco; Nederlandse organisatie voor Wetenschappelijk Onderzoek (NWO), the Netherlands; The National Science Centre, Poland (2015/18/E/ST2/00758); National Authority for Scientific Research (ANCS), Romania; Ministerio de Ciencia, Innovacion, Investigacion y Universidades (MCIU): Programa Estatal de Generacion de Conocimiento (refs. PGC2018-096663-B-C41, -A-C42, -B-C43, -B-C44) (MCIU/FEDER), Severo Ochoa Centre of Excellence and MultiDark Consolider (MCIU), Junta de Andalucia (ref. SOMM17/6104/UGR), Generalitat Valenciana: Grisolia (ref. GRISOLIA/2018/119) and GenT (ref. CIDEGENT/2018/034) programs, La Caixa Foundation (ref. LCF/BQ/IN17/11620019), EU: MSC program (ref. 713673), Spain., The KM3NeT research infrastructure is currently under construction at two locations in the Mediterranean Sea. The KM3NeT/ORCA water-Cherenkov neutrino detector off the French coast will instrument several megatons of seawater with photosensors. Its main objective is the determination of the neutrino mass ordering. This work aims at demonstrating the general applicability of deep convolutional neural networks to neutrino telescopes, using simulated datasets for the KM3NeT/ORCA detector as an example. To this end, the networks are employed to achieve reconstruction and classification tasks that constitute an alternative to the analysis pipeline presented for KM3NeT/ORCA in the KM3NeT Letter of Intent. They are used to infer event reconstruction estimates for the energy, the direction, and the interaction point of incident neutrinos. The spatial distribution of Cherenkov light generated by charged particles induced in neutrino interactions is classified as shower- or track-like, and the main background processes associated with the detection of atmospheric neutrinos are recognized. Performance comparisons to machine-learning classification and maximum-likelihood reconstruction algorithms previously developed for KM3NeT/ORCA are provided. It is shown that this application of deep convolutional neural networks to simulated datasets for a large-volume neutrino telescope yields competitive reconstruction results and performance improvements with respect to classical approaches., French National Research Agency (ANR) ANR-15-CE31-0020, Centre National de la Recherche Scientifique (CNRS), Commission Europeenne (FEDER fund), European Union (EU), Institut Universitaire de France (IUF), LabEx UnivEarthS ANR-10-LABX-0023 ANR-18-IDEX-0001, Shota Rustaveli National Science Foundation of Georgia FR-18-1268, German Research Foundation (DFG), Greek Ministry of Development-GSRT, Istituto Nazionale di Fisica Nucleare (INFN), Ministry of Education, Universities and Research (MIUR) Research Projects of National Relevance (PRIN), Ministry of Higher Education, Scientific Research and Professional Training, Morocco, Netherlands Organization for Scientific Research (NWO), National Science Centre, Poland 2015/18/E/ST2/00758, National Authority for Scientific Research (ANCS), Romania, Ministerio de Ciencia, Innovacion, Investigacion y Universidades PGC2018-096663-B-C41 A-C42 B-C43 B-C44, Severo Ochoa Centre of Excellence, Junta de Andalucia SOMM17/6104/UGR, Generalitat Valenciana: Grisolia GRISOLIA/2018/119 CIDEGENT/2018/034, La Caixa Foundation LCF/BQ/IN17/11620019, EU: MSC program 713673
Published: 2020

35. Comparison of initial and second opinion reads of multiparametric magnetic resonance imaging of the prostate for transperineal template-guided biopsies with MRI-Ultrasound fusion

Author: Silvia Selinski, Thorsten H. Ecke, Steffen Hallmann, Gregorij Nesterov, Stefan Koch, Stephan Koswig, Tristan Barrett, Vincent J. Gnanapragasam, and Dagmar Schwaiger
Subjects: Image-Guided Biopsy, Male, medicine.medical_specialty, Prostate biopsy, Urology, 030232 urology & nephrology, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Prostate, Biopsy, medicine, Humans, Multiparametric Magnetic Resonance Imaging, Aged, Ultrasonography, Aged, 80 and over, medicine.diagnostic_test, business.industry, Transperineal biopsy, Prostatic Neoplasms, Cancer, Magnetic resonance imaging, Rectal examination, Middle Aged, medicine.disease, Magnetic Resonance Imaging, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Radiology, business
Abstract: Purpose To investigate the value of second-opinion evaluation of multiparametric prostate magnetic resonance imaging (MRI) by subspecialised uroradiologists for the detection of significant cancer in transperineal fusion prostate biopsy. Methods The evaluated data included age, PSA (ng/ml), PSA density, Gleason score, digital rectal examination (DRE), prostate volume of 149 patients. Twenty-seven patients (18%) had no previous prostate biopsy, 114 patients (77%) had a previous negative biopsy, and 8 patients (5%) were on active surveillance. Using PI-RADS v2 scores for mpMRI a second report was performed by a specialist uroradiologist. In all cases a subsequent transperineal biopsy was performed with at least 2 cores per target and additional background systemic cores. Initial and second-opinion radiology reports were evaluated for detection of any cancer and Gleason score (GS) 7-10 cancer, including positive predictive value and negative (NPV) and compared by Fisher's exact test. Results At transperineal biopsy, 51 % (76/149) of patients had a GS 6-10 prostate cancer (PCa), 27 % (40/149) of patients had a GS 3 + 3 PCa and 12 % (18/149) a GS 3 + 4 and 12 % (18/149) had a GS ≥4 + 3 PCa. Agreement between initial and second-opinion reads was observed in 57.7% (86/149; kappa value = 0.32). The detection of clinically significant cancers with second-opinion reads was significantly higher (0.61; 17/28) compared to initial reads (0.35; 17/49); P = 0.034. Conclusions Second reading of prostate mpMRIs by subspecialised uroradiologists significantly improved the positive predictive value for detection of clinically significant prostate cancer and showed a trend towards improved NPV for MRI-negative cases where biopsy could be safely avoided. Urologists should be aware that the experience of the reporter will affect the report when making decisions if and how to obtain biopsies. Reporter experience may help to reduce overcalling and avoid over-targeting of lesions.
Published: 2021

36. Sensitivity of the KM3NeT/ARCA neutrino telescope to point-like neutrino sources

Author: T. Thakore, J. Zúñiga, Soebur Razzaque, C. De Sio, Antoine Kouchner, V. Bertin, Alessia Capone, Joao A B Coelho, A. Enzenhöfer, P.M. Kooijman, Alba Domi, D. Calvo, Silvia Celli, Stefano Ottonello, M. Colomer Molla, Salvatore Viola, R. Muller, S. R. Gozzini, D. Zaborov, Nhan Chau, C. Biernoth, A. Giuliante, H. Brânzaş, Thomas Eberl, M. Lotze, M. de Jong, A. Sharma, D. Stransky, Vladimir Kulikovskiy, Mario Musumeci, N. Randazzo, Dídac Diego-Tortosa, V. Popa, R. Bruijn, A. Martini, Vitaliano Chiarella, J. Manczak, Fabio Marzaioli, F. Raffaelli, L. K. Resvanis, P. de Jong, E. Buis, D. Stavropoulos, Steffen Hallmann, Gisela Anton, V. Sciacca, A. Rovelli, Abdelilah Moussa, M. Morganti, Sebastiano Aiello, J. Brunner, Michael Kreter, Francesca Tatone, Louis-Marie Rigalleau, Ofelia Pisanti, A. Sinopoulou, S.F. Biagi, E. A. De Wolf, Corinne Donzaud, G. Grella, L. Martin, E. Tenllado, E. Tzamariudaki, Paolo Fermani, S. Sánchez Navas, Alessandro Lonardo, M. Perrin-Terrin, Luigi Antonio Fusco, Timothée Grégoire, P. Coyle, Giulia Illuminati, Emanuele Leonora, Carlo Alessandro Nicolau, A. Orlando, Raffaele Buompane, Giacomo Cuttone, Piotr Kalaczyński, L. Quinn, I. Di Palma, C. Poirè, Antonio F. Díaz, P. Piattelli, D. Dornic, D. Kießling, V. Panagopoulos, C. Markou, Francesco Simeone, H. van Haren, Kay Graf, Karel Melis, G. Maggi, K. Pikounis, D. van Eijk, Giuseppina Larosa, H. Hamdaoui, Sara Pulvirenti, M. Ardid, Hassnae Eljarrari, Rosanna Cocimano, M. Organokov, M. Dörr, M. Jongen, Matthias Kadler, B. Ó Fearraigh, Fabio Longhitano, N. R. Khan Chowdhury, Mohamed Chabab, M. Circella, Robert Lahmann, J.J. Hernández-Rey, R. Le Breton, F. Versari, T. Gal, D. Lopez Coto, R. Mele, M. Saffer, C. Distefano, D. F. E. Samtleben, I. Salvadori, Andrea Biagioni, Yahya Tayalati, Giuseppe Levi, Simona Maria Stellacci, Jos Steijger, L. Nauta, A. Hekalo, P. Migliozzi, V. Van Elewyck, M. Bouta, T. Avgitas, M. Post, Antonio D'Onofrio, J. Seneca, C. Bagatelas, R. Donà, M. Taiuti, Tommaso Chiarusi, Miroslav Filipovic, Carlos Maximiliano Mollo, Rezo Shanidze, Annarita Margiotta, Diego Real, Riccardo Papaleo, J. Barrios-Martí, Richard Dallier, Thierry Pradier, Michel André, S.E. Akrame, G. Androulakis, J. Reubelt, T. Heid, Matteo Sanguineti, L. Maderer, G. Pühlhofer, A.M. van den Berg, Jörn Wilms, A. Trovato, G. Polydefki, Francesco Leone, Massimiliano Lincetto, A. Belias, D. Tzanetatos, Julien Aublin, Bruny Baret, Cristiano Bozza, Els Koffeman, G. Riccobene, T. Stüven, U. Katz, Daniele Vivolo, R. Coniglione, I. El Bojaddaini, Maurizio Spurio, M. Anghinolfi, J. Busto, G.E. Păvălaş, A.J. Heijboer, A. Garcia, L. S. Miranda, G. C. Barbarino, M. Durocher, Silvio Cherubini, Carmelo Pellegrino, F. Garufi, J. Hofestädt, Andrea Santangelo, E. Migneco, B. Spisso, M. Richer, E. Berbee, G. Ferrara, Jihad Boumaaza, I. Sgura, R. Gracia, J. Schumann, O. Kalekin, M. Bruchner, P. Mijakowski, M. Kunhikannan Kannichankandy, G. Papalashvili, Karl Mannheim, Lucio Gialanella, J.D. Zornoza, Domenico Santonocito, Michael Moser, E. G. Anassontzis, Dominik Elsaesser, C. Nielsen, A. Creusot, S. Bourret, B. Strandberg, C. W. James, A. Marinelli, A. Sánchez Losa, M.C. Bouwhuis, Paolo Sapienza, J.A. Martínez-Mora, Alexis Coleiro, Dario Grasso, Fabrizio Ameli, Emidio Giorgio, KM3NeT (IHEF, IoP, FNWI), ATLAS (IHEF, IoP, FNWI), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de physique subatomique et des technologies associées (SUBATECH), Université de Nantes - Faculté des Sciences et des Techniques, Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), KM3NeT, Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Aiello, S, Akrame, Se, Ameli, F, Anassontzis, Eg, Andre, M, Androulakis, G, Anghinolfi, M, Anton, G, Ardid, M, Aublin, J, Avgitas, T, Bagatelas, C, Barbarino, G, Baret, B, Barrios-Marti, J, Belias, A, Berbee, E, van den Berg, A, Bertin, V, Biagi, S, Biagioni, A, Biernoth, C, Boumaaza, J, Bourret, S, Bouta, M, Bouwhuis, M, Bozza, C, Branzas, H, Bruchner, M, Bruijn, R, Brunner, J, Buis, E, Buompane, R, Busto, J, Calvo, D, Capone, A, Celli, S, Chabab, M, Chau, N, Cherubini, S, Chiarella, V, Chiarusi, T, Circella, M, Cocimano, R, Coelho, Jab, Coleiro, A, Molla, Mc, Coniglione, R, Coyle, P, Creusot, A, Cuttone, G, D'Onofrio, A, Dallier, R, De Sio, C, Di Palma, I, Diaz, Af, Diego-Tortosa, D, Distefano, C, Domi, A, Dona, R, Donzaud, C, Dornic, D, Dorr, M, Durocher, M, Eberl, T, van Eijk, D, El Bojaddaini, I, Eljarrari, H, Elsaesser, D, Enzenhofer, A, Fermani, P, Ferrara, G, Filipovic, Md, Fusco, La, Gal, T, Garcia, A, Garufi, F, Gialanella, L, Giorgio, E, Giuliante, A, Gozzini, Sr, Gracia, R, Graf, K, Grasso, D, Gregoire, T, Grella, G, Hallmann, S, Hamdaoui, H, van Haren, H, Heid, T, Heijboer, A, Hekalo, A, Hernandez-Rey, Jj, Hofestadt, J, Illuminati, G, James, Cw, Jongen, M, de Jong, M, de Jong, P, Kadler, M, Kalaczynski, P, Kalekin, O, Katz, Uf, Chowdhury, Nrk, Kiessling, D, Koffeman, En, Kooijman, P, Kouchner, A, Kreter, M, Kulikovskiy, V, Kannichankandy, Mk, Lahmann, R, Larosa, G, Le Breton, R, Leone, F, Leonora, E, Levi, G, Lincetto, M, Lonardo, A, Longhitano, F, Coto, Dl, Lotze, M, Maderer, L, Maggi, G, Manczak, J, Mannheim, K, Margiotta, A, Marinelli, A, Markou, C, Martin, L, Martinez-Mora, Ja, Martini, A, Marzaioli, F, Mele, R, Melis, Kw, Migliozzi, P, Migneco, E, Mijakowski, P, Miranda, L, Mollo, Cm, Morganti, M, Moser, M, Moussa, A, Muller, R, Musumeci, M, Nauta, L, Navas, S, Nicolau, Ca, Nielsen, C, Fearraigh, Bo, Organokov, M, Orlando, A, Ottonello, S, Panagopoulos, V, Papalashvili, G, Papaleo, R, Pavalas, Ge, Pellegrino, C, Perrin-Terrin, M, Piattelli, P, Pikounis, K, Pisanti, O, Poire, C, Polydefki, G, Popa, V, Post, M, Pradier, T, Puhlhofer, G, Pulvirenti, S, Quinn, L, Raffaelli, F, Randazzo, N, Razzaque, S, Real, D, Resvanis, L, Reubelt, J, Riccobene, G, Richer, M, Rigalleau, L, Rovelli, A, Saffer, M, Salvadori, I, Samtleben, Dfe, Losa, A, Sanguineti, M, Santangelo, A, Santonocito, D, Sapienza, P, Schumann, J, Sciacca, V, Seneca, J, Sgura, I, Shanidze, R, Sharma, A, Simeone, F, Sinopoulou, A, Spisso, B, Spurio, M, Stavropoulos, D, Steijger, J, Stellacci, Sm, Strandberg, B, Stransky, D, Stuven, T, Taiuti, M, Tatone, F, Tayalati, Y, Tenllado, E, Thakore, T, Trovato, A, Tzamariudaki, E, Tzanetatos, D, Van Elewyck, V, Versari, F, Viola, S, Vivolo, D, Wilms, J, de Wolf, E, Zaborov, D, Zornoza, Jd, Zuniga, J, Aiello, S., Akrame, S.E., Ameli, F., G. Anassontzis, E., Andre, M., Androulakis, G., Anghinolfi, M., Anton, G., Ardid, M., Aublin, J., Avgitas, T., Bagatelas, C., Barbarino, G., Baret, B., Barrios-Martí, J., Belias, A., Berbee, E., van den Berg, A., Bertin, V., Biagi, S., Biagioni, A., Biernoth, C., Boumaaza, J., Bourret, S., Bouta, M., Bouwhuis, M., Bozza, C., Brânzaş, H., Bruchner, M., Bruijn, R., Brunner, J., Buis, E., Buompane, R., Busto, J., Calvo, D., Capone, A., Celli, S., Chabab, M., Chau, N., Cherubini, S., Chiarella, V., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J.A.B., Coleiro, A., Molla, M. Colomer, Coniglione, R., Coyle, P., Creusot, A., Cuttone, G., D'Onofrio, A., Dallier, R., De Sio, C., Di Palma, I., Díaz, A.F., Diego-Tortosa, D., Distefano, C., Domi, A., Donà, R., Donzaud, C., Dornic, D., Dörr, M., Durocher, M., Eberl, T., van Eijk, D., El Bojaddaini, I., Eljarrari, H., Elsaesser, D., Enzenhöfer, A., Fermani, P., Ferrara, G., D. Filipović, M., Fusco, L.A., Gal, T., Garcia, A., Garufi, F., Gialanella, L., Giorgio, E., Giuliante, A., Gozzini, S.R., Gracia, R., Graf, K., Grasso, D., Grégoire, T., Grella, G., Hallmann, S., Hamdaoui, H., van Haren, H., Heid, T., Heijboer, A., Hekalo, A., Hernández-Rey, J.J., Hofestädt, J., Illuminati, G., James, C.W., Jongen, M., de Jong, M., de Jong, P., Kadler, M., Kalaczyński, P., Kalekin, O., Katz, U.F., Khan Chowdhury, N.R., Kießling, D., Koffeman, E.N., Kooijman, P., Kouchner, A., Kreter, M., Kulikovskiy, V., Kunhikannan Kannichankandy, M., Lahmann, R., Larosa, G., Le Breton, R., Leone, F., Leonora, E., Levi, G., Lincetto, M., Lonardo, A., Longhitano, F., Lopez Coto, D., Lotze, M., Maderer, L., Maggi, G., Mańczak, J., Mannheim, K., Margiotta, A., Marinelli, A., Markou, C., Martin, L., Martínez-Mora, J.A., Martini, A., Marzaioli, F., Mele, R., Melis, K.W., Migliozzi, P., Migneco, E., Mijakowski, P., Miranda, L.S., Mollo, C.M., Morganti, M., Moser, M., Moussa, A., Muller, R., Musumeci, M., Nauta, L., Navas, S., Nicolau, C.A., Nielsen, C., Ó Fearraigh, B., Organokov, M., Orlando, A., Ottonello, S., Panagopoulos, V., Papalashvili, G., Papaleo, R., Păvălaş, G.E., Pellegrino, C., Perrin-Terrin, M., Piattelli, P., Pikounis, K., Pisanti, O., Poiré, C., Polydefki, G., Popa, V., Post, M., Pradier, T., Pühlhofer, G., Pulvirenti, S., Quinn, L., Raffaelli, F., Randazzo, N., Razzaque, S., Real, D., Resvanis, L., Reubelt, J., Riccobene, G., Richer, M., Rigalleau, L., Rovelli, A., Saffer, M., Salvadori, I., Samtleben, D.F.E., Sánchez Losa, A., Sanguineti, M., Santangelo, A., Santonocito, D., Sapienza, P., Schumann, J., Sciacca, V., Seneca, J., Sgura, I., Shanidze, R., Sharma, A., Simeone, F., Sinopoulou, A., Spisso, B., Spurio, M., Stavropoulos, D., Steijger, J., Stellacci, S.M., Strandberg, B., Stransky, D., Stüven, T., Taiuti, M., Tatone, F., Tayalati, Y., Tenllado, E., Thakore, T., Trovato, A., Tzamariudaki, E., Tzanetatos, D., Van Elewyck, V., Versari, F., Viola, S., Vivolo, D., Wilms, J., de Wolf, E., Zaborov, D., Zornoza, J.D., Zúñiga, J., Akrame, S. E., Barrios-Marti, J., VAN DEN BERG, Michiel, DI BIAGI, Paola, Branzas, H., Buompane, Angela, Coelho, J. A. B., Molla, M. C., Diaz, A. F., Distefano, Giuliana, Dona, R., Dorr, M., VAN EIJK, Ernst, Enzenhofer, A., Filipovic, Jelena, Fusco, L. A., Sambataro, GIOVANNI ANTONIO LUCA, Gozzini, S. R., Gregoire, T., Hernandez-Rey, J. J., Hofestadt, J., James, C. W., DE JONGE, KRISTA VIRGINIA, Kalaczynski, P., Katz, U. F., Khan Chowdhury, N. R., Kiessling, D., Koffeman, E. N., Levi, Donata, Manczak, J., Martinez-Mora, J. A., Melis, K. W., Miranda, L. S., Mollo, C. M., Nicolau, C. A., O Fearraigh, B., Pavalas, G. E., Piattelli, Adriano, Poire, C., Popa, CRISTINA MARIA, Puhlhofer, G., Pulvirenti, Emanuela, Samtleben, D. F. E., Sanchez Losa, A., SPURIO VENNARUCCI, Giacomo, Stellacci, S. M., Stuven, T., Tatone, Carla, Zornoza, J. D., Zuniga, J., Research unit Astroparticle Physics, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Ferrara, Giuseppina, and D. Filipovic, M.
Subjects: Astrofísica, PARTICLE-ACCELERATION, neutrino: energy: high, Flux, Astrophysics, telescope, 01 natural sciences, 7. Clean energy, neutrino: flux, neutrino, site, Cherenkov, gamma ray: flux, 010303 astronomy & astrophysics, KM3NeT, High Energy Astrophysical Phenomena (astro-ph.HE), Physics, Astrophysical neutrino source, astro-ph.HE, Astrophysics::Instrumentation and Methods for Astrophysics, COSMIC-RAYS, Supernova, neutrino: detector, Neutrino detector, GALACTIC SOURCES, Neutrino, Astrophysics - High Energy Astrophysical Phenomena, REMNANT RX J1713.7-3946, sources, [PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], Astrophysical neutrino sources, Astrophysics::High Energy Astrophysical Phenomena, SHELL, FOS: Physical sciences, Cosmic ray, underwater, ICECUBE, hadronic, Astrophysical, 0103 physical sciences, supernova, Neutrins, 14. Life underwater, Neutrinos, Cherenkov underwater neutrino telescope, 010308 nuclear & particles physics, resolution, Astronomy and Astrophysics, Galactic plane, sensitivity, Neutrino astrophysics, Galaxy, 13. Climate action, Física::Astronomia i astrofísica [Àrees temàtiques de la UPC], FISICA APLICADA, network, RADIATION, TEV, galaxy, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Abstract: KM3NeT will be a network of deep-sea neutrino telescopes in the Mediterranean Sea. The KM3NeT/ARCA detector, to be installed at the Capo Passero site (Italy), is optimised for the detection of high-energy neutrinos of cosmic origin. Thanks to its geographical location on the Northern hemisphere, KM3NeT/ARCA can observe upgoing neutrinos from most of the Galactic Plane, including the Galactic Centre. Given its effective area and excellent pointing resolution, KM3NeT/ARCA will measure or significantly constrain the neutrino flux from potential astrophysical neutrino sources. At the same time, it will test flux predictions based on gamma-ray measurements and the assumption that the gamma-ray flux is of hadronic origin. Assuming this scenario, discovery potentials and sensitivities for a selected list of Galactic sources and to generic point sources with an $E^{-2}$ spectrum are presented. These spectra are assumed to be time independent. The results indicate that an observation with $3\sigma$ significance is possible in about six years of operation for the most intense sources, such as Supernovae Remnants RX\,J1713.7-3946 and Vela Jr. If no signal will be found during this time, the fraction of the gamma-ray flux coming from hadronic processes can be constrained to be below 50\% for these two objects., Comment: 32 pages, 9 figures, submitted to Astroparticle Physics
Published: 2019

37. Letter of interest for a neutrino beam from Protvino to KM3NeT/ORCA

Author: Uli Katz, J. Aublin, A. V. Maximov, R. Bruijn, Alexander Zaitsev, J. Seneca, A. Sinopoulou, A. Domi, R. Yu. Sinyukov, M. Organokov, B. Ó Fearraigh, P. de Jong, O. P. Lebedev, N. R. Khan Chowdhury, Simona Maria Stellacci, E. G. Anassontzis, K. Melis, M. Colomer Molla, M. D. Skorokhvatov, M. Taiuti, C. Donzaud, Massimiliano Lincetto, Miguel Ardid, V. I. Garkusha, R. Le Breton, Vincent Bertin, L. Quinn, Vadim A. Naumov, I. Sokalski, C. Poirè, A. A. Sokolov, V. Kulikovskiy, F. N. Novoskoltsev, J.D. Zornoza, T. Thakore, S. V. Ivanov, D. Zaborov, B. Strandberg, T. Pradier, Mohamed Chabab, S. Sánchez Navas, S. R. Gozzini, E. Litvinovich, L. Nauta, K. S. Kuzmin, A. Creusot, Robert Muller, Matteo Sanguineti, E. Shirokov, Thomas Eberl, A. Kouchner, G. de Wasseige, Christos Markou, K. Graf, M. Kirsanov, C. W. James, A. Heijboer, A. V. Akindinov, D. Lopez-Coto, Miroslav Filipovic, Steffen Hallmann, C. Nielsen, T. Gal, T. Grégoire, G. Grella, A. S. Chepurnov, G. Papalashvili, D. F. E. Samtleben, N. Chau, L.A. Fusco, V. Van Elewyck, J. Hofestädt, J. Brunner, Juan José Hernández-Rey, E. A. De Wolf, S. Bourret, I. D. Kakorin, A. Enzenhöfer, P. Coyle, M. Faifman, Cristiano Bozza, Gisela Anton, E. Tzamariudaki, P. Kalaczynski, M. Perrin-Terrin, B. Baret, M. de Jong, M. Bruchner, B. Spisso, Rezo Shanidze, J. Zúñiga, KM3NeT (IHEF, IoP, FNWI), IHEF (IoP, FNWI), IoP (FNWI), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), and Ministerio de Ciencia, Innovación y Universidades (España)
Subjects: Sterile neutrino, Physics - Instrumentation and Detectors, Physics and Astronomy (miscellaneous), Physics::Instrumentation and Detectors, beam transport, particle source: design, 7. Clean energy, 01 natural sciences, High Energy Physics - Experiment, Nucleon, Scattering, High Energy Physics - Experiment (hep-ex), [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Lepton polarization, neutrino oscillation, neutrino: mass, KM3NeT, Physics, P2O, neutrino: energy spectrum, Detector, phase: CP, near detector: design, Instrumentation and Detectors (physics.ins-det), p: beam, matter: effect, Total cross-section, CP violation, Neutrino, FOS: Physical sciences, lcsh:Astrophysics, neutrino: beam, Nuclear physics, Energy-Range, 0103 physical sciences, lcsh:QB460-466, lcsh:Nuclear and particle physics. Atomic energy. Radioactivity, Charged-Current interactions, 14. Life underwater, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, Neutrino oscillation, numerical calculations, neutrino nucleon: scattering, Engineering (miscellaneous), Ratio, activity report, 010308 nuclear & particles physics, ORCA, Nu-Mu, neutrino: particle source, Deuterium, sensitivity, FISICA APLICADA, accelerator: upgrade, lcsh:QC770-798, Physics::Accelerator Physics, High Energy Physics::Experiment, Beam (structure)
Abstract: The Protvino accelerator facility located in the Moscow region, Russia, is in a good position to offer a rich experimental research program in the field of neutrino physics. Of particular interest is the possibility to direct a neutrino beam from Protvino towards the KM3NeT/ORCA detector, which is currently under construction in the Mediterranean Sea 40 km offshore Toulon, France. This proposal is known as P2O. Thanks to its baseline of 2595 km, this experiment would yield an unparalleled sensitivity to matter effects in the Earth, allowing for the determination of the neutrino mass ordering with a high level of certainty after only a few years of running at a modest beam intensity of $\approx$ 90 kW. With a prolonged exposure ($\approx$ 1500 kW*yr), a 2$\sigma$ sensitivity to the leptonic CP-violating Dirac phase can be achieved. A second stage of the experiment, comprising a further intensity upgrade of the accelerator complex and a densified version of the ORCA detector (Super-ORCA), would allow for up to a 6$\sigma$ sensitivity to CP violation and a 10$^\circ$-17$^\circ$ resolution on the CP phase after 10 years of running with a 450 kW beam, competitive with other planned experiments. The initial composition and energy spectrum of the neutrino beam would need to be monitored by a near detector, to be constructed several hundred meters downstream from the proton beam target. The same neutrino beam and near detector set-up would also allow for neutrino-nucleus cross section measurements to be performed. A short-baseline sterile neutrino search experiment would also be possible., Comment: 27 pages, 15 figures, 2 tables
Published: 2019

38. Measuring the atmospheric neutrino oscillation parameters and constraining the 3+1 neutrino model with ten years of ANTARES data

Author: Jose Busto, T. Thakore, J. Zúñiga, A. Enzenhöfer, A. Salah-Eddine, M. Taiuti, Daniele Vivolo, S. Navas, V. Bertin, Th. Stolarczyk, G.E. Păvălaş, Thierry Pradier, T. Grégoire, M. Kreter, Massimiliano Lincetto, D. Drouhin, B. Belhorma, R. Mele, Gisela Anton, Giuseppe Levi, J. Hößl, I. Kreykenbohm, Vladimir Kulikovskiy, R. Gracia Ruiz, Giulia Illuminati, Alba Domi, F. Versari, C. Lachaud, Paolo Fermani, I. El Bojaddaini, C. Nielsen, Carmelo Pellegrino, R. Cherkaoui El Moursli, V. Popa, J. Brunner, M. Organokov, P. Migliozzi, M. Perrin-Terrin, T. Avgitas, P. Piattelli, Steffen Hallmann, Giovanna Ferrara, J-J. Aubert, M. Circella, J.D. Zornoza, D. Zaborov, S. Loucatos, C. Racca, S.F. Biagi, Corinne Donzaud, I. Salvadori, Paolo Sapienza, O. Kalekin, M. Jongen, Anne Deschamps, Bruny Baret, Matthias Kadler, C. Distefano, H. van Haren, R. Gozzini, Heide Costantini, D. F. E. Samtleben, R. Le Breton, Matteo Sanguineti, Kay Graf, Karel Melis, H. Brânzaş, Yann Hello, A. Creusot, G. Riccobene, N. Randazzo, S. Bourret, Damien Dornic, A. Nuñez, Alessia Capone, J. Barrios-Martí, G. Maggi, J.A. Martínez-Mora, M. Colomer, Jörn Wilms, Farida Fassi, N.R. Khan-Chowdhury, Robert Lahmann, C. W. James, R. Donà, A. Marinelli, Maurizio Spurio, J. Carr, A.J. Heijboer, A. Ettahiri, Tommaso Chiarusi, Luigi Antonio Fusco, Dominique Lefèvre, M.C. Bouwhuis, M. de Jong, Annarita Margiotta, Michel André, R. Bormuth, M. Marcelin, Emanuele Leonora, Dominik Elsässer, Hervé Glotin, V. Van Elewyck, Mohamed Chabab, U. Katz, F. Schüssler, M. Ardid, M. Anghinolfi, N. El Khayati, S. Basa, L. Quinn, J.J. Hernández-Rey, Yahya Tayalati, A. Trovato, L. Caramete, Arnauld Albert, R. Coniglione, J. Hofestädt, Jihad Boumaaza, Silvia Celli, Thomas Eberl, M. Lotze, Antoine Kouchner, A. Sánchez-Losa, P. Coyle, Alexis Coleiro, E. Nezri, J. Aublin, Salvatore Viola, R. Bruijn, Abdelilah Moussa, I. Di Palma, Antonio F. Díaz, B. Vallage, KM3NeT (IHEF, IoP, FNWI), ANTARES (IHEF, IoP, FNWI), IHEF (IoP, FNWI), Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Laboratoire de Physique de Clermont (LPC), Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Géoazur (GEOAZUR 7329), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Université Paris-Sud - Paris 11 (UP11), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Informatique et Systèmes (LIS), Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Institut méditerranéen d'océanologie (MIO), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Groupe de Recherche en Physique des Hautes Energies (GRPHE), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-IUT de Colmar, Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), ANTARES, Albert, A., Andre, M., Anghinolfi, M., Anton, G., Ardid, M., Aubert, J. -J., Aublin, J., Avgitas, T., Baret, B., Barrios-Marti, J., Basa, S., Belhorma, B., Bertin, V., Biagi, S., Bormuth, R., Boumaaza, J., Bourret, S., Bouwhuis, M. C., Branzas, H., Bruijn, R., Brunner, J., Busto, J., Capone, A., Caramete, L., Carr, J., Celli, S., Chabab, M., Cherkaoui El Moursli, R., Chiarusi, T., Circella, M., Coleiro, A., Colomer, M., Coniglione, R., Costantini, H., Coyle, P., Creusot, A., Diaz, A. F., Deschamps, A., Distefano, C., Di Palma, I., Domi, A., Dona, R., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., El Bojaddaini, I., El Khayati, N., Elsasser, D., Enzenhofer, A., Ettahiri, A., Fassi, F., Fermani, P., Ferrara, G., Fusco, L., Gay, P., Glotin, H., Gozzini, R., Gregoire, T., Gracia Ruiz, R., Graf, K., Hallmann, S., van Haren, H., Heijboer, A. J., Hello, Y., Hernandez-Rey, J. J., Hossl, J., Hofestadt, J., Illuminati, G., James, C. W., de Jong, M., Jongen, M., Kadler, M., Kalekin, O., Katz, U., Khan-Chowdhury, N. R., Kouchner, A., Kreter, M., Kreykenbohm, I., Kulikovskiy, V., Lachaud, C., Lahmann, R., Le Breton, R., Lefevre, D., Leonora, E., Levi, G., Lincetto, M., Lotze, M., Loucatos, S., Maggi, G., Marcelin, M., Margiotta, A., Marinelli, A., Martinez-Mora, J. A., Mele, R., Melis, K., Migliozzi, P., Moussa, A., Navas, S., Nezri, E., Nielsen, C., Nunez, A., Organokov, M., Pavalas, G. E., Pellegrino, C., Perrin-Terrin, M., Piattelli, P., Popa, V., Pradier, T., Quinn, L., Racca, C., Randazzo, N., Riccobene, G., Sanchez-Losa, A., Salah-Eddine, A., Salvadori, I., Samtleben, D. F. E., Sanguineti, M., Sapienza, P., Schussler, F., Spurio, M., Stolarczyk, T., Taiuti, M., Tayalati, Y., Thakore, T., Trovato, A., Vallage, B., Van Elewyck, V., Versari, F., Viola, S., Vivolo, D., Wilms, J., Zaborov, D., Zornoza, J. D., Zuniga, J., Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Clermont Auvergne (UCA)-Centre National de la Recherche Scientifique (CNRS), Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut Universitaire de Technologie de Colmar, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Ministerio de Economía y Competitividad (España), Albert, A, Andre, M, Anghinolfi, M, Anton, G, Ardid, M, Aubert, Jj, Aublin, J, Avgitas, T, Baret, B, Barrios-Marti, J, Basa, S, Belhorma, B, Bertin, V, Biagi, S, Bormuth, R, Boumaaza, J, Bourret, S, Bouwhuis, Mc, Branzas, H, Bruijn, R, Brunner, J, Busto, J, Capone, A, Caramete, L, Carr, J, Celli, S, Chabab, M, El Moursli, Rc, Chiarusi, T, Circella, M, Coleiro, A, Colomer, M, Coniglione, R, Costantini, H, Coyle, P, Creusot, A, Diaz, Af, Deschamps, A, Distefano, C, Di Palma, I, Domi, A, Dona, R, Donzaud, C, Dornic, D, Drouhin, D, Eberl, T, El Bojaddaini, I, El Khayati, N, Elsasser, D, Enzenhofer, A, Ettahiri, A, Fassi, F, Fermani, P, Ferrara, G, Fusco, L, Gay, P, Glotin, H, Gozzini, R, Gregoire, T, Ruiz, Rg, Graf, K, Hallmann, S, van Haren, H, Heijboer, Aj, Hello, Y, Hernandez-Rey, Jj, Hossl, J, Hofestadt, J, Illuminati, G, James, Cw, de Jong, M, Jongen, M, Kadler, M, Kalekin, O, Katz, U, Khan-Chowdhury, Nr, Kouchner, A, Kreter, M, Kreykenbohm, I, Kulikovskiy, V, Lachaud, C, Lahmann, R, Le Breton, R, Lefevre, D, Leonora, E, Levi, G, Lincetto, M, Lotze, M, Loucatos, S, Maggi, G, Marcelin, M, Margiotta, A, Marinelli, A, Martinez-Mora, Ja, Mele, R, Melis, K, Migliozzi, P, Moussa, A, Navas, S, Nezri, E, Nielsen, C, Nunez, A, Organokov, M, Pavalas, Ge, Pellegrino, C, Perrin-Terrin, M, Piattelli, P, Popa, V, Pradier, T, Quinn, L, Racca, C, Randazzo, N, Riccobene, G, Sanchez-Losa, A, Salah-Eddine, A, Salvadori, I, Samtleben, Dfe, Sanguineti, M, Sapienza, P, Schussler, F, Spurio, M, Stolarczyk, T, Taiuti, M, Tayalati, Y, Thakore, T, Trovato, A, Vallage, B, Van Elewyck, V, Versari, F, Viola, S, Vivolo, D, Wilms, J, Zaborov, D, Zornoza, Jd, Zuniga, J, Albert A., Andre M., Anghinolfi M., Anton G., Ardid M., Aubert J.-J., Aublin J., Avgitas T., Baret B., Barrios-Marti J., Basa S., Belhorma B., Bertin V., Biagi S., Bormuth R., Boumaaza J., Bourret S., Bouwhuis M.C., Branzas H., Bruijn R., Brunner J., Busto J., Capone A., Caramete L., Carr J., Celli S., Chabab M., Cherkaoui El Moursli R., Chiarusi T., Circella M., Coleiro A., Colomer M., Coniglione R., Costantini H., Coyle P., Creusot A., Diaz A.F., Deschamps A., Distefano C., Di Palma I., Domi A., Dona R., Donzaud C., Dornic D., Drouhin D., Eberl T., El Bojaddaini I., El Khayati N., Elsasser D., Enzenhofer A., Ettahiri A., Fassi F., Fermani P., Ferrara G., Fusco L., Gay P., Glotin H., Gozzini R., Gregoire T., Gracia Ruiz R., Graf K., Hallmann S., van Haren H., Heijboer A.J., Hello Y., Hernandez-Rey J.J., Hossl J., Hofestadt J., Illuminati G., James C.W., de Jong M., Jongen M., Kadler M., Kalekin O., Katz U., Khan-Chowdhury N.R., Kouchner A., Kreter M., Kreykenbohm I., Kulikovskiy V., Lachaud C., Lahmann R., Le Breton R., Lefevre D., Leonora E., Levi G., Lincetto M., Lotze M., Loucatos S., Maggi G., Marcelin M., Margiotta A., Marinelli A., Martinez-Mora J.A., Mele R., Melis K., Migliozzi P., Moussa A., Navas S., Nezri E., Nielsen C., Nunez A., Organokov M., Pavalas G.E., Pellegrino C., Perrin-Terrin M., Piattelli P., Popa V., Pradier T., Quinn L., Racca C., Randazzo N., Riccobene G., Sanchez-Losa A., Salah-Eddine A., Salvadori I., Samtleben D.F.E., Sanguineti M., Sapienza P., Schussler F., Spurio M., Stolarczyk T., Taiuti M., Tayalati Y., Thakore T., Trovato A., Vallage B., Van Elewyck V., Versari F., Viola S., Vivolo D., Wilms J., Zaborov D., Zornoza J.D., Zuniga J., Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Centre National de la Recherche Scientifique (CNRS)-Université de Toulon (UTLN)-Aix Marseille Université (AMU)-Institut de Recherche pour le Développement (IRD), Institut Universitaire de Technologie de Colmar-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Aix Marseille Université (AMU)-Centre National d'Études Spatiales [Toulouse] (CNES), Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Toulon (UTLN), and COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])
Subjects: Astrofísica, Sterile neutrino, Physics::Instrumentation and Detectors, 01 natural sciences, 7. Clean energy, High Energy Physics - Experiment, neutrino/mu: atmosphere, High Energy Physics - Experiment (hep-ex), energy: threshold, High Energy Physics - Phenomenology (hep-ph), neutrino: atmosphere, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Muon neutrino, S067P23, Physics, Neutrino detectors and telescopes (experiments), Oscillation, 4. Education, Astrophysics::Instrumentation and Methods for Astrophysics, neutrino: sterile, Neutrino Detectors and Telescopes (experiments), High Energy Physics - Phenomenology, neutrino: detector, Neutrino detector, Neutrino, Atmospheric neutrino, Nuclear and High Energy Physics, Particle physics, Astrophysics::High Energy Astrophysical Phenomena, Neutrino telescope, neutrino: mass difference, FOS: Physical sciences, statistical analysis, S067DM1, 0103 physical sciences, lcsh:Nuclear and particle physics. Atomic energy. Radioactivity, Neutrins, Neutrinos, 010306 general physics, Neutrino oscillation, neutrino: model, ANTARES, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, neutrino: mixing angle, Neutrino astrophysics, 13. Climate action, [PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph], Física::Astronomia i astrofísica [Àrees temàtiques de la UPC], FISICA APLICADA, lcsh:QC770-798, High Energy Physics::Experiment, neutrino: oscillation, experimental results
Abstract: The ANTARES neutrino telescope has an energy threshold of a few tens of GeV. This allows to study the phenomenon of atmospheric muon neutrino disappearance due to neutrino oscillations. In a similar way, constraints on the 3+1 neutrino model, which foresees the existence of one sterile neutrino, can be inferred. Using data collected by the ANTARES neutrino telescope from 2007 to 2016, a new measurement of m2 32 and 23 has been performed | which is consistent with world best- t values | and constraints on the 3+1 neutrino model have been derived., Centre National de la Recherche Scienti que (CNRS), Commissariat a l' energie atomique et aux energies alternatives (CEA), Commission Européenne (FEDER fund and Marie Curie Program), Institut Universitaire de France (IUF), IdEx program and UnivEarthS Labex program at Sorbonne Paris Cité (ANR-10-LABX-0023 and ANR-11-IDEX-0005-02), Labex OCEVU (ANR-11-LABX-0060) and the A*MIDEX project (ANR-11-IDEX-0001-02), Région ÎIle-de- France (DIM-ACAV), Région Alsace (contrat CPER), Région Provence-Alpes-Côte d'Azur, Département du Var and Ville de La Seyne-sur-Mer, Bundesministerium für Bildung und Forschung (BMBF), Istituto Nazionale di Fisica Nucleare (INFN), Nederlandse organisatie voor Wetenschappelijk Onderzoek (NWO), Council of the President of the Russian Federation for young scientists and leading scientific schools supporting grants, Executive Unit for Financing Higher Education, Research, Development and Innovation (UEFISCDIÇ), Ministerio de Economía y Competitividad (MINECO): Plan Estatal de Investigación (refs. FPA2015-65150-C3-1-P, -2-P and -3-P, (MINECO/FEDER)), Severo Ochoa Centre of Excellence and Red Consolider MultiDark (MINECO), and Prometeo and Grisolía programs (Generalitat Valenciana), Ministry of Higher Education, Scienti c Research and Professional Training
Published: 2019

39. UBC® Rapid Test—A Urinary Point-of-Care (POC) Assay for Diagnosis of Bladder Cancer with a focus on Non-Muscle Invasive High-Grade Tumors: Results of a Multicenter-Study

Author: Steffen Hallmann, Sarah Weiß, Thomas Otto, Dimitri Barski, Carsten Stephan, Holger Gerullis, Thorsten H. Ecke, and Christian Arndt
Subjects: medicine.medical_specialty, Urinary system, 030232 urology & nephrology, Urology, Urine, Catalysis, lcsh:Chemistry, Inorganic Chemistry, 03 medical and health sciences, 0302 clinical medicine, Medicine, Physical and Theoretical Chemistry, lcsh:QH301-705.5, Molecular Biology, Spectroscopy, Urinary bladder, Bladder cancer, Receiver operating characteristic, urinary based diagnostics, business.industry, fungi, Organic Chemistry, Area under the curve, General Medicine, medicine.disease, Computer Science Applications, medicine.anatomical_structure, lcsh:Biology (General), lcsh:QD1-999, tumor markers, 030220 oncology & carcinogenesis, Cohort, Biomarker (medicine), bladder cancer, business
Abstract: Objectives: UBC&reg, Rapid Test measures soluble fragments of cytokeratins 8 and 18 in urine. We present results of a multicenter study using an updated version of UBC&reg, Rapid Test in bladder cancer patients, patients with urinary bladder cancer positive history, and healthy controls. Material and Methods: In total 530 urine samples have been included in this study. Clinical urine samples were used from 242 patients with tumors of the urinary bladder (134 non-muscle-invasive low-grade tumors (NMI-LG), 48 non-muscle-invasive high-grade tumors (NMI-HG), and 60 muscle-invasive high-grade tumors (MI-HG)), 62 patients with non-evidence of disease (NED), and 226 healthy controls. Urine samples were analyzed by the UBC&reg, Rapid point-of-care (POC) assay and evaluated by Concile Omega 100 POC Reader. All statistical analyses have been performed using R version 3.2.3. Results: Elevated levels of UBC&reg, Rapid Test in urine are higher in patients with bladder cancer in comparison to the control group (p &lt, 0.001). The sensitivity for the whole bladder cancer cohort was 53.3% (positive predictive value (PPV) 90.2%, negative predictive value (NPV) 65.2%) and was 38.8% (PPV 78.8%, NPV 72.1%) for non-muscle-invasive low-grade bladder cancer, 75.0% (PPV 72.0%, NPV 94.7%) for non-muscle-invasive high-grade bladder cancer and 68.3% (PPV 74.6%, NPV 91.8%) for muscle-invasive high-grade bladder cancer. The specificity for the statistical calculations was 93.8%. The cut-off value (10 &micro, g/L) was evaluated for the whole patient cohort. The area under the curve of the quantitative UBC&reg, Rapid Test using the optimal threshold obtained by receiver operating characteristics (ROC) analysis was 0.774. Elevated values of UBC&reg, Rapid Test in urine are higher in patients with high-grade bladder cancer in comparison to low-grade tumors and the healthy control group. Conclusions: UBC&reg, Rapid Test has potential to be a clinically valuable urinary protein biomarker for detection of high-grade bladder cancer patients and could be added in the management of NMI-HG tumors. UBC&reg, Rapid results generated in both study centers in the present multicenter study are very similar and reproducible. Furthermore UBC&reg, Rapid Test is standardized and calibrated and thus independent of used batch of test as well as study site.
Published: 2018
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40. Successful evacuation of large perirenal hematoma after extracorporeal shock wave lithotripsy (ESWL) ‐ step 1 of the IDEAL recommendations of surgical innovation

Author: Steffen Hallmann, Thorsten H. Ecke, Jürgen Ruttloff, and Jan Petersein
Subjects: medicine.medical_specialty, medicine.medical_treatment, 030232 urology & nephrology, Case Report, Case Reports, Lithotripsy, lithotripsy, urologic and male genital diseases, 03 medical and health sciences, Normal renal function, 0302 clinical medicine, Hematoma, medicine, Urokinase, business.industry, extracorporeal shock wave lithotripsy, Renal tissue, General Medicine, medicine.disease, Extracorporeal shock wave lithotripsy, Surgery, perirenal hematoma, 030220 oncology & carcinogenesis, Perirenal hematoma, Radiology, business, Complication, medicine.drug
Abstract: Key Clinical Message Larger perirenal hematomas after extracorporeal shock wave lithotripsy (ESWL) are sometimes related to the loss of renal function due to compression of the normal renal tissue. After computed tomography-guided drainage and locally applied urokinase, the hematoma was fractionally evacuated. This procedure is a save and fast way to recover normal renal function.
Published: 2017

41. UBC

Author: Thorsten H, Ecke, Sarah, Weiß, Carsten, Stephan, Steffen, Hallmann, Christian, Arndt, Dimitri, Barski, Thomas, Otto, and Holger, Gerullis
Subjects: Adult, Aged, 80 and over, Male, urinary based diagnostics, Muscles, Point-of-Care Systems, fungi, Middle Aged, Article, ROC Curve, Urinary Bladder Neoplasms, tumor markers, Humans, bladder cancer, Biological Assay, Female, Neoplasm Invasiveness, Neoplasm Grading, Aged
Abstract: Objectives: UBC® Rapid Test measures soluble fragments of cytokeratins 8 and 18 in urine. We present results of a multicenter study using an updated version of UBC® Rapid Test in bladder cancer patients, patients with urinary bladder cancer positive history, and healthy controls. Material and Methods: In total 530 urine samples have been included in this study. Clinical urine samples were used from 242 patients with tumors of the urinary bladder (134 non-muscle-invasive low-grade tumors (NMI-LG), 48 non-muscle-invasive high-grade tumors (NMI-HG), and 60 muscle-invasive high-grade tumors (MI-HG)), 62 patients with non-evidence of disease (NED), and 226 healthy controls. Urine samples were analyzed by the UBC® Rapid point-of-care (POC) assay and evaluated by Concile Omega 100 POC Reader. All statistical analyses have been performed using R version 3.2.3. Results: Elevated levels of UBC® Rapid Test in urine are higher in patients with bladder cancer in comparison to the control group (p < 0.001). The sensitivity for the whole bladder cancer cohort was 53.3% (positive predictive value (PPV) 90.2%, negative predictive value (NPV) 65.2%) and was 38.8% (PPV 78.8%, NPV 72.1%) for non-muscle-invasive low-grade bladder cancer; 75.0% (PPV 72.0%, NPV 94.7%) for non-muscle-invasive high-grade bladder cancer and 68.3% (PPV 74.6%, NPV 91.8%) for muscle-invasive high-grade bladder cancer. The specificity for the statistical calculations was 93.8%. The cut-off value (10 µg/L) was evaluated for the whole patient cohort. The area under the curve of the quantitative UBC® Rapid Test using the optimal threshold obtained by receiver operating characteristics (ROC) analysis was 0.774. Elevated values of UBC® Rapid Test in urine are higher in patients with high-grade bladder cancer in comparison to low-grade tumors and the healthy control group. Conclusions: UBC® Rapid Test has potential to be a clinically valuable urinary protein biomarker for detection of high-grade bladder cancer patients and could be added in the management of NMI-HG tumors. UBC® Rapid results generated in both study centers in the present multicenter study are very similar and reproducible. Furthermore UBC® Rapid Test is standardized and calibrated and thus independent of used batch of test as well as study site.
Published: 2018

42. The SUrvey for Pulsars and Extragalactic Radio Bursts – II. New FRB discoveries and their follow-up

Author: Matthew Bailes, T. A. Pritchard, Mitchell B. Mickaliger, A. Trovato, C. Lachaud, Maurizio Spurio, A.J. Heijboer, M. Anghinolfi, N. El Khayati, Ivan Felis, Daniele Vivolo, S. Loucatos, Utane Sawangwit, M. Marcelin, R. Coniglione, Paolo Sapienza, A. Klotz, J. Zúñiga, S.F. Biagi, Dominique Lefèvre, Jörn Wilms, J. Hofestädt, Alba Domi, C. Racca, Silvia Celli, D. Dornic, S. Basa, M. de Jong, I. El Bojaddaini, A. Marinelli, V. Popa, Dominik Elsässer, Tomonori Totani, V. Bertin, M. Circella, Timothée Grégoire, A. Ettahiri, A. Sánchez-Losa, C. Pellegrino, Anne Deschamps, Yann Hello, Matteo Sanguineti, Eric Howell, Steffen Hallmann, J. Carr, Annarita Margiotta, Antoine Kouchner, M. Saldaña, M.C. Bouwhuis, J. A. Green, Michel André, F. Schüssler, I. Salvadori, D. Turpin, Paolo Piattelli, R. Bormuth, Thomas Eberl, Sarah Burke-Spolaor, Richard Wilson, R. Mele, C. Perrina, Alessandro Corongiu, Tommaso Chiarusi, G.E. Păvălaş, Hervé Glotin, V. Van Elewyck, J. Busto, Pablo Torne, P. Jaroenjittichai, E. Petroff, E. Nezri, V. Venkatraman Krishnan, M. Jongen, V. Morello, P. Migliozzi, A. Creusot, G. De Bonis, Joao Coelho, R. Bruijn, J. Hößl, T. Avgitas, Jürgen Brunner, D. Kießling, Federico Versari, M. Organokov, C. Distefano, Juan José Hernández-Rey, O. Kalekin, D. F. E. Samtleben, M. Taiuti, C. Tönnis, A. Enzenhöfer, Giulia Illuminati, I. Di Palma, J.A. Martínez-Mora, Alexis Coleiro, M. Caleb, C. Hugon, C. Sieger, Michael Kramer, H. Brânzaş, J-J. Aubert, Emanuele Leonora, Antonio F. Díaz, P. Coyle, Poonam Chandra, L. Caramete, Giorgio Riccobene, F. Jankowski, Richard Dodson, Th. Stolarczyk, J.D. Zornoza, B. Vallage, Alessio Trois, Vladimir Kulikovskiy, Miguel Ardid, B. Belhorma, Chris Flynn, M. Kreter, Gisela Anton, A. Jameson, A. Vizzocca, V. Giordano, A. Capone, H. van Haren, Timothy Butterley, T. Pradier, R. Cherkaoui El Moursli, Evan Keane, S. Bourret, Ralph Eatough, David Coward, W. van Straten, S. Navas, Delphine Perrodin, U. F. Katz, V. S. Dhillon, Farida Fassi, I. Andreoni, E. D. Barr, C. W. James, Kay Graf, Karel Melis, Jeff Cooke, S. P. Littlefair, Arnauld Albert, Caterina Tiburzi, T. R. Marsh, N. D. R. Bhat, L. K. Hardy, Abdelilah Moussa, Doriane Drouhin, Benjamin Stappers, I. Kreykenbohm, Yuu Niino, Bruny Baret, Simon Johnston, Robert Lahmann, A. Possenti, L. Quinn, Shivani Bhandari, Nozomu Tominaga, Yahya Tayalati, R. Gracia-Ruiz, Tsuyoshi Terai, H. Costantini, J. Barrios-Martí, Luigi Antonio Fusco, Matthias Kadler, T. Michael, T. W. B. Muxlow, M. Burgay, C. Donzaud, Institut de recherche en astrophysique et planétologie (IRAP), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Groupe de Recherche en Physique des Hautes Energies (GRPHE), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut Universitaire de Technologie de Colmar, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Observatoire de la Côte d'Azur (OCA), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11), Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Laboratoire des Sciences de l'Information et des Systèmes (LSIS), Centre National de la Recherche Scientifique (CNRS)-Arts et Métiers Paristech ENSAM Aix-en-Provence-Université de Toulon (UTLN)-Aix Marseille Université (AMU), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Institut méditerranéen d'océanologie (MIO), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut Pluridisciplinaire Hubert Curien (IPHC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), ANTARES, Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Aix Marseille Université (AMU)-Centre National d'Études Spatiales [Toulouse] (CNES), Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Clermont Auvergne (UCA)-Centre National de la Recherche Scientifique (CNRS), Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Arts et Métiers Paristech ENSAM Aix-en-Provence-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université de Toulon (UTLN)-Aix Marseille Université (AMU)-Institut de Recherche pour le Développement (IRD), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-IUT de Colmar, Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Département de Physique des Particules (ex SPP) (DPhP), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de recherche en astrophysique et planétologie ( IRAP ), Université Paul Sabatier - Toulouse 3 ( UPS ) -Observatoire Midi-Pyrénées ( OMP ) -Centre National de la Recherche Scientifique ( CNRS ), Centre de Physique des Particules de Marseille ( CPPM ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Aix Marseille Université ( AMU ), AstroParticule et Cosmologie ( APC - UMR 7164 ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ), Laboratoire d'Astrophysique de Marseille ( LAM ), Aix Marseille Université ( AMU ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National d'Etudes Spatiales ( CNES ) -Centre National de la Recherche Scientifique ( CNRS ), Observatoire de la Côte d'Azur ( OCA ), Centre National de la Recherche Scientifique ( CNRS ), Université Paris-Sud - Paris 11 ( UP11 ), Laboratoire de Physique de Clermont ( LPC ), Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Université Clermont Auvergne ( UCA ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire des Sciences de l'Information et des Systèmes ( LSIS ), Aix Marseille Université ( AMU ) -Université de Toulon ( UTLN ) -Arts et Métiers Paristech ENSAM Aix-en-Provence-Centre National de la Recherche Scientifique ( CNRS ), Institut méditerranéen d'océanologie ( MIO ), Centre National de la Recherche Scientifique ( CNRS ) -Université de Toulon ( UTLN ) -Aix Marseille Université ( AMU ) -Institut de Recherche pour le Développement ( IRD ), Département de Physique des Particules (ex SPP) ( DPP ), Institut de Recherches sur les lois Fondamentales de l'Univers ( IRFU ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay, Institut Pluridisciplinaire Hubert Curien ( IPHC ), Centre National de la Recherche Scientifique ( CNRS ) -Université de Strasbourg ( UNISTRA ), Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), KM3NeT (IHEF, IoP, FNWI), Bhandari, S, Keane, Ef, Barr, Ed, Jameson, A, Petroff, E, Johnston, S, Bailes, M, Bhat, Ndr, Burgay, M, Burke-Spolaor, S, Caleb, M, Eatough, Rp, Flynn, C, Green, Ja, Jankowski, F, Kramer, M, Krishnan, Vv, Morello, V, Possenti, A, Stappers, B, Tiburzi, C, van Straten, W, Andreoni, I, Butterley, T, Chandra, P, Cooke, J, Corongiu, A, Coward, Dm, Dhillon, V, Dodson, R, Hardy, Lk, Howell, Ej, Jaroenjittichai, P, Klotz, A, Littlefair, Sp, Marsh, Tr, Mickaliger, M, Muxlow, T, Perrodin, D, Pritchard, T, Sawangwit, U, Terai, T, Tominaga, N, Torne, P, Totani, T, Trois, A, Turpin, D, Niino, Y, Wilson, Rw, Albert, A, Andre, M, Anghinolfi, M, Anton, G, Ardid, M, Aubert, Jj, Avgitas, T, Baret, B, Barrios-Marti, J, Basa, S, Belhorma, B, Bertin, V, Biagi, S, Bormuth, R, Bourret, S, Bouwhuis, Mc, Branzas, H, Bruijn, R, Brunner, J, Busto, J, Capone, A, Caramete, L, Carr, J, Celli, S, El Moursli, Rc, Chiarusi, T, Circella, M, Coelho, Jab, Coleiro, A, Coniglione, R, Costantini, H, Coyle, P, Creusot, A, Diaz, Af, Deschamps, A, De Bonis, G, Distefano, C, Di Palma, I, Domi, A, Donzaud, C, Dornic, D, Drouhin, D, Eberl, T, El Bojaddaini, I, Khayati, N, Elasser, D, Enzenhoefer, A, Ettahiri, A, Fassi, F, Felis, I, Fusco, La, Gay, P, Giordano, V, Glotin, H, Gregoire, T, Gracia-Ruiz, R, Graf, K, Hallmann, S, van Haren, H, Heijboer, Aj, Hello, Y, Hernandez-Rey, Jj, Hossl, J, Hofestadt, J, Hugon, C, Illuminati, G, James, Cw, de Jong, M, Jongen, M, Kadler, M, Kalekin, O, Katz, U, Kiessling, D, Kouchner, A, Kreter, M, Kreykenbohm, I, Kulikovskiy, V, Lachaud, C, Lahmann, R, Lefevere, D, Leonora, E, Loucatos, S, Marcelin, M, Margiotta, A, Marinelli, A, Martinez-Mora, Ja, Mele, R, Melis, K, Michael, T, Migliozzi, P, Moussa, A, Navas, S, Nezri, E, Organokov, M, Pavalas, Ge, Pellegrino, C, Perrina, C, Piattelli, P, Popa, V, Pradier, T, Quinn, L, Racca, C, Riccobene, G, Sanchez-Losa, A, Saldana, M, Salvadori, I, Samtleben, Dfe, Sanguineti, M, Sapienza, P, Schussler, F, Sieger, C, Spurio, M, Stolarczyk, T, Taiuti, M, Tayalati, Y, Trovato, A, Tonnis, C, Vallage, B, Van Elewyck, V, Versari, F, Vivolo, D, Vizzocca, A, Wilms, J, Zornoza, Jd, Zuniga, J, Bhandari, S., Keane, E.F., Barr, E.D., Jameson, A., Petroff, E., Johnston, S., Bailes, M., Bhat, N.D.R., Burgay, M., Burke-Spolaor, S., Caleb, M., Eatough, R.P., Flynn, C., Green, J.A., Jankowski, F., Kramer, M., Venkatraman Krishnan, V., Morello, V., Possenti, A., Stappers, B., Tiburzi, C., van Straten, W., Andreoni, I., Butterley, T., Chandra, P., Cooke, J., Corongiu, A., Coward, D.M., Dhillon, V.S., Dodson, R., Hardy, L.K., Howell, E.J., Jaroenjittichai, P., Klotz, A., Littlefair, S.P., Marsh, T.R., Mickaliger, M., Muxlow, T., Perrodin, D., Pritchard, T., Sawangwit, U., Terai, T., Tominaga, N., Torne, P., Totani, T., Trois, A., Turpin, D., Niino, Y., Wilson, R.W., Albert, A., André, M., Anghinolfi, M., Anton, G., Ardid, M., Aubert, J.-J., Avgitas, T., Baret, B., Barrios-Martí, J., Basa, S., Belhorma, B., Bertin, V., Biagi, S., Bormuth, R., Bourret, S., Bouwhuis, M.C., Brănzas, H., Bruijn, R., Brunner, J., Busto, J., Capone, A., Caramete, L., Carr, J., Celli, S., El Moursli, R. Cherkaoui, Chiarusi, T., Circella, M., Coelho, J.A.B., Coleiro, A., Coniglione, R., Costantini, H., Coyle, P., Creusot, A., Díaz, A.F., Deschamps, A., De Bonis, G., Distefano, C., Di Palma, I., Domi, A., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., El Bojaddaini, I., El Khayati, N., Elsässer, D., Enzenhöfer, A., Ettahiri, A., Fassi, F., Felis, I., Fusco, L.A., Gay, P., Giordano, V., Glotin, H., Gregoire, T., Gracia-Ruiz, R., Graf, K., Hallmann, S., van Haren, H., Heijboer, A.J., Hello, Y., Hernández-Rey, J.J., Hößl, J., Hofestädt, J., Hugon, C., Illuminati, G., James, C.W., de Jong, M., Jongen, M., Kadler, M., Kalekin, O., Katz, U., Kießling, D., Kouchner, A., Kreter, M., Kreykenbohm, I., Kulikovskiy, V., Lachaud, C., Lahmann, R., Lefevre, D., Leonora, E., Loucatos, S., Marcelin, M., Margiotta, A., Marinelli, A., Martínez-Mora, J.A., Mele, R., Melis, K., Michael, T., Migliozzi, P., Moussa, A., Navas, S., Nezri, E., Organokov, M., Pavalas, G.E., Pellegrino, C., Perrina, C., Piattelli, P., Popa, V., Pradier, T., Quinn, L., Racca, C., Riccobene, G., Sánchez-Losa, A., Saldana, M., Salvadori, I., Samtleben, D.F.E., Sanguineti, M., Sapienza, P., Schüssler, F., Sieger, C., Spurio, M., Stolarczyk, Th., Taiuti, M., Tayalati, Y., Trovato, A., Tönnis, C., Vallage, B., Van Elewyck, V., Versari, F., Vivolo, D., Vizzocca, A., Wilms, J., Zornoza, J.D., Zúniga, J., Keane, E. F., Barr, E. D., Bhat, N. D. R., Eatough, R. P., Green, J. A., Coward, D. M., Dhillon, V. S., Hardy, L. K., Howell, E. J., Littlefair, S. P., Marsh, T. R., Wilson, R. W., Andre, M., Aubert, J. -J., Barrios-Marti, J., Bouwhuis, M. C., Branzas, H., El Moursli, R. C., Coelho, J. A. B., Diaz, A. F., Elsasser, D., Enzenhofer, A., Fusco, L. A., Heijboer, A. J., Hernandez-Rey, J. J., Hossl, J., Hofestadt, J., James, C. W., Kiessling, D., Martinez-Mora, J. A., Pavalas, G. E., Sanchez-Losa, A., Samtleben, D. F. E., Schussler, F., Stolarczyk, T., Tonnis, C., Zornoza, J. D., and Zuniga, J.
Subjects: surveys – intergalactic medium, [ PHYS.ASTR ] Physics [physics]/Astrophysics [astro-ph], data analysis, Astrophysics, Surveys, 7. Clean energy, 01 natural sciences, radiation mechanisms, observational surveys, intergalactic medium, radio continuum, Astronomical observatories, Methods: Data analysis, Survey, data analysis [Methods], 010303 astronomy & astrophysics, media_common, general [Radiation mechanisms], Physics, High Energy Astrophysical Phenomena (astro-ph.HE), Fast radio burst, general [Radio continuum], Canadian Hydrogen Intensity Mapping Experiment, Intergalactic medium, Methods: Observational, Radiation mechanisms: General, Radio continuum: General, Neutrino, Observatoris astronòmics, Astrophysics - High Energy Astrophysical Phenomena, general [adio continuum], media_common.quotation_subject, FOS: Physical sciences, Methods: Data analysi, Radio telescope, Pulsar, 0103 physical sciences, Radiation mechanisms, observational [Methods], Source counts, Telescopis, Astronomy and Astrophysics, Space and Planetary Science, 010308 nuclear & particles physics, radiation mechanisms: general, methods: data analysis, methods: observational, radio continuum: general, Astronomy, Astronomy and Astrophysic, Afterglow, Radio continuum, 13. Climate action, Sky, FISICA APLICADA, Física::Astronomia i astrofísica [Àrees temàtiques de la UPC], data analysi [methods], [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Telescopes
Abstract: SB would like to thank Tara Murphy, Martin Bell, Paul Hancock, Keith Bannister, Chris Blake and Bing Zhang for useful discussions., We report the discovery of four Fast Radio Bursts (FRBs) in the ongoing SUrvey for Pulsars and Extragalactic Radio Bursts at the Parkes Radio Telescope: FRBs 150610, 151206, 151230 and 160102. Our real-time discoveries have enabled us to conduct extensive, rapid multimessenger follow-up at 12 major facilities sensitive to radio, optical, X-ray, gamma-ray photons and neutrinos on time-scales ranging from an hour to a few months post-burst. No counterparts to the FRBs were found and we provide upper limits on afterglow luminosities. None of the FRBs were seen to repeat. Formal fits to all FRBs show hints of scattering while their intrinsic widths are unresolved in time. FRB 151206 is at low Galactic latitude, FRB 151230 shows a sharp spectral cut-off, and FRB 160102 has the highest dispersion measure (DM = 2596.1 ± 0.3 pc cm−3) detected to date. Three of the FRBs have high dispersion measures (DM > 1500 pc cm−3), favouring a scenario where the DM is dominated by contributions from the intergalactic medium. The slope of the Parkes FRB source counts distribution with fluences >2 Jy ms is α=−2.2+0.6−1.2 and still consistent with a Euclidean distribution (α = −3/2). We also find that the all-sky rate is 1.7+1.5−0.9×103 FRBs/(4π sr)/day above ∼2Jyms and there is currently no strong evidence for a latitude-dependent FRB sky rate., The Parkes radio telescope and the Australia Telescope Compact Array are part of the Australia Telescope National Facility which is funded by the Commonwealth of Australia for operation as a National Facility managed by CSIRO. Parts of this research were conducted by the Australian Research Council Centre of Excellence for All-sky Astrophysics (CAASTRO), through project number CE110001020. The GMRT is run by the National Centre for Radio Astrophysics of the Tata Institute of Fundamental Research. VLAis run by theNational Radio Astronomy Observatory (NRAO). NRAO is a facility of the National Science Foundation operated under cooperative agreement by Associated Universities, Inc. This work was performed on the gSTAR national facility at Swinburne University of Technology. gSTAR is funded by Swinburne and the Australian Government’s Education Investment Fund. This work is also based on data collected at Subaru Telescope, which is operated by the National Astronomical Observatory of Japan. We thank the LSST Project for making their code available as free software at http://dm.lsstcorp.org. Funding from the European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013) / ERC Grant Agreement n. 617199 (EP). Access to the Lovell Telescope is supported through an STFC consolidated grant. The 100-m telescope in Effelsberg is operation by the Max- Planck-Institut für Radioastronomie with funds of the Max-Planck Society. The Sardinia Radio Telescope (SRT) is funded by the Department of University and Research (MIUR), the Italian Space Agency (ASI), and the Autonomous Region of Sardinia (RAS) and is operated as National Facility by the National Institute for Astrophysics (INAF). TB and RWW are grateful to the STFC for financial support (grant reference ST/P000541/1). Research support to IA is provided by the Australian Astronomical Observatory. The ANTARES authors acknowledge the financial support of the funding agencies: Centre National de la Recherche Scientifique (CNRS), Commissariat à l’énergie atomique et aux énergies alternatives (CEA), Commission Européenne (FEDER fund and Marie Curie Program), Institut Universitaire de France (IUF), IdEx program and UnivEarthS Labex program at Sorbonne Paris Cité (ANR-10- LABX-0023 and ANR-11-IDEX-0005-02), Labex OCEVU (ANR- 11-LABX-0060) and the A*MIDEX project (ANR-11-IDEX-0001- 02), Région Île-de-France (DIM-ACAV), Région Alsace (contrat CPER), Région Provence-Alpes-Côte d’Azur, Département du Var and Ville de La Seyne-sur-Mer, France; Bundesministerium für Bildung und Forschung (BMBF), Germany; IstitutoNazionale di Fisica Nucleare (INFN), Italy; Stichting voor Fundamenteel Onderzoek der Materie (FOM), Nederlandse organisatie voor Wetenschappelijk Onderzoek (NWO), the Netherlands; Council of the President of the Russian Federation for young scientists and leading scientific schools supporting grants, Russia; National Authority for Scientific Research (ANCS), Romania; Ministerio de Economía y Competitividad (MINECO): Plan Estatal de Investigación (refs. FPA2015- 65150-C3-1-P, -2-P and -3-P, (MINECO/FEDER)), Severo Ochoa Centre of Excellence and MultiDark Consolider (MINECO), and Prometeo and Grisolía programs (Generalitat Valenciana), Spain; Ministry of Higher Education, Scientific Research and Professional Training, Morocco. We also acknowledge the technical support of Ifremer, AIM and Foselev Marine for the sea operation and the CC-IN2P3 for the computing facilities. This work made use of data supplied by the UK Swift Science Data Centre at the University of Leicester. This research has made use of data, software and/or web tools obtained from the High Energy Astrophysics Science Archive Research Center (HEASARC), a service of the Astrophysics Science Division at NASA/GSFC and of the Smithsonian Astrophysical Observatory’s High Energy Astrophysics Division. This work is based in part on data collected at Subaru Telescope, which is operated by the National Astronomical Observatory of Japan. This paper makes use of software developed for the Large Synoptic Survey Telescope. We thank the LSST Project for making their code available as free software at http://dm.lsstcorp.org. RPE/MK gratefully acknowledges support from ERC Synergy Grant "BlackHoleCam" Grant Agreement Number 610058
Published: 2018

43. Characterisation of the Hamamatsu photomultipliers for the KM3NeT Neutrino Telescope

Author: Carmelo Pellegrino, F. Garufi, S.E. Akrame, A. Martini, U. Katz, Stavroula Tsagkli, D. van Eijk, T. Stüven, Rosanna Cocimano, A. Orlando, M. Anghinolfi, Piotr Kalaczyński, Vladimir Kulikovskiy, P. Timmer, Luigi Antonio Fusco, Maurizio Spurio, L. de Waardt, A.J. Heijboer, Rezo Shanidze, R. Gracia Ruiz, M. Jongen, F. Versari, J. Manczak, B. Schermer, Alessia Capone, P.M. Kooijman, J. Brunner, T. Gal, E. Migneco, B. Spisso, M. Richer, C. Distefano, Raffaele Buompane, Robert Lahmann, Lucio Gialanella, J. Seneca, E. Buis, Els Koffeman, D. F. E. Samtleben, A. Hekalo, A. Trovato, D. Tzanetatos, P. Migliozzi, Cristiano Bozza, E. Berbee, I. Di Palma, G. Ferrara, B. Jongewaard, Antonio F. Díaz, D. Zaborov, Paolo Sapienza, H. van Haren, S. Geißelsöder, Sebastiano Aiello, G. Pühlhofer, T. Avgitas, Fabio Longhitano, M. Taiuti, G. E. Poma, Francesco Simeone, G. Polydefki, R. Donà, L. Nauta, S. Loucatos, B. Vallage, G. Grella, G. Maggi, Carlos Maximiliano Mollo, P. Mijakowski, Tommaso Chiarusi, M. Perrin-Terrin, Matteo Sanguineti, Robert Muller, Massimiliano Lincetto, Alessandro Lonardo, S. Bourret, J. Barrios-Martí, Giuseppe Levi, Silvia Celli, V. Sciacca, M. Dörr, Thierry Pradier, Carlo Alessandro Nicolau, G. Riccobene, S.F. Biagi, E. A. De Wolf, G.E. Păvălaş, Emanuele Leonora, O. Kalekin, Michel André, C. Poirè, Corinne Donzaud, A. Marinelli, R. Coniglione, A. Sánchez Losa, I. El Bojaddaini, V. Bertin, A. Belias, A.M. van den Berg, V. Van Elewyck, Kay Graf, Karel Melis, J.D. Zornoza, E. Tenllado, C. De Sio, Antoine Kouchner, Mohamed Chabab, Antonio D'Onofrio, J. Hofestädt, Michael Moser, L. S. Miranda, Fabio Marzaioli, F. Raffaelli, M.C. Bouwhuis, Matthias Kadler, Daniele Vivolo, Jörn Wilms, Richard Dallier, H. Brânzaş, Giulia Illuminati, Alba Domi, D. Calvo, Jihad Boumaaza, Andrea Santangelo, R. Bormuth, Diego Real, R. Le Breton, M. Baars, I. Sgura, M. Colomer Molla, Salvatore Viola, Soebur Razzaque, Sara Pulvirenti, Thomas Eberl, P. Piattelli, M. Lotze, A. Sharma, Ofelia Pisanti, M. Volkert, Vitaliano Chiarella, G. Kieft, S. Navas, Jose Busto, A. Enzenhöfer, J. Reubelt, T. Heid, Mario Musumeci, D. Kießling, T. Grégoire, L. K. Resvanis, P. de Jong, C. Biernoth, V. Popa, T. Thakore, N. Randazzo, J. Zúñiga, D. Stavropoulos, M. Organokov, C. Nielsen, N. R. Khan Chowdhury, B. Strandberg, Damien Dornic, Jos Steijger, V. Panagopoulos, Simona Maria Stellacci, J. Aublin, A. Rovelli, Abdelilah Moussa, M. de Jong, R. Mele, J.A. Martínez-Mora, Alexis Coleiro, Michael Kreter, Dario Grasso, Fabrizio Ameli, Steffen Hallmann, Joao A B Coelho, Francesca Tatone, R. Bruijn, Emidio Giorgio, E. G. Anassontzis, C. Bagatelas, M. Ardid, J. Pérez Romero, Dominik Elsaesser, L. Quinn, L. Martin, I. Salvadori, C. W. James, Annarita Margiotta, Gisela Anton, Bruny Baret, S. R. Gozzini, M. Post, K. Pikounis, A. Creusot, N. Briukhanova, C. Markou, E. Tzamariudaki, Claudia Valieri, Riccardo Papaleo, A. Giuliante, G. C. Barbarino, J.J. Hernández-Rey, Yahya Tayalati, M. Durocher, G. Androulakis, Silvio Cherubini, S. Gauchery, L. Caramete, G. Papalashvili, D. Stransky, M. Circella, Karl Mannheim, Andrea Biagioni, G. Pellegrini, A. Sinopoulou, M. Morganti, P. Coyle, Giacomo Cuttone, Francesco Leone, AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Laboratoire de physique subatomique et des technologies associées (SUBATECH), Université de Nantes - Faculté des Sciences et des Techniques, Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, KM3NeT, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Aiello, S., Akrame, S. E., Ameli, F., Anassontzis, E. G., Andre, M., Androulakis, G., Anghinolfi, M., Anton, G., Ardid, M., Aublin, J., Avgitas, T., Baars, M., Bagatelas, C., Barbarino, G., Baret, B., Barrios-Martí, J., Belias, A., Berbee, E., Berg, A. Van Den, Bertin, V., Biagi, S., Biagioni, A., Biernoth, C., Bormuth, R., Boumaaza, J., Bourret, S., Bouwhuis, M., Bozza, C., Branzaş, H., Briukhanova, N., Bruijn, R., Brunner, J., Buis, E., Buompane, R., Busto, J., Calvo, D., Capone, A., Caramete, L., Celli, S., Chabab, M., Cherubini, S., Chiarella, V., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Molla, M. Colomer, Coniglione, R., Coyle, P., Creusot, A., Cuttone, G., D'Onofrio, A., Dallier, R., Sio, C. De, Palma, I. Di, Díaz, A. F., Distefano, C., Domi, A., Donà, R., Donzaud, C., Dornic, D., Dörr, M., Durocher, M., Eberl, T., Eijk, D. Van, Bojaddaini, I. El, Elsaesser, D., Enzenhöfer, A., Ferrara, G., Fusco, L. A., Gal, T., Garufi, F., Gauchery, S., Geißelsöder, S., Gialanella, L., Giorgio, E., Giuliante, A., Gozzini, S. R., Ruiz, R. Gracia, Graf, K., Grasso, D., Grégoire, T., Grella, G., Hallmann, S., Haren, H. Van, Heid, T., Heijboer, A., Hekalo, A., Hernández-Rey, J. J., Hofestädt, J., Illuminati, G., James, C. W., Jongen, M., Jongewaard, B., De Jong, M., De Jong, P., Kadler, M., Kalaczyński, P., Kalekin, O., Katz, U. F., Chowdhury, N. R. Khan, Kieft, G., Kießling, D., Koffeman, E. N., Kooijman, P., Kouchner, A., Kreter, M., Kulikovskiy, V., Lahmann, R., Breton, R. Le, Leone, F., Leonora, E., Levi, G., Lincetto, M., Lonardo, A., Longhitano, F., Lotze, M., Loucatos, S., Maggi, G., Mańczak, J., Mannheim, K., Margiotta, A., Marinelli, A., Markou, C., Martin, L., Martínez-Mora, J. A., Martini, A., Marzaioli, F., Mele, R., Melis, K. W., Migliozzi, P., Migneco, E., Mijakowski, P., Miranda, L. S., Mollo, C. M., Morganti, M., Moser, M., Moussa, A., Muller, R., Musumeci, M., Nauta, L., Navas, S., Nicolau, C. A., Nielsen, C., Organokov, M., Orlando, A., Panagopoulos, V., Papalashvili, G., Papaleo, R., Pǎvǎlaş, G. E., Pellegrini, G., Pellegrino, C., Pérez Romero, J., Perrin-Terrin, M., Piattelli, P., Pikounis, K., Pisanti, O., Poirè, C., Polydefki, G., Poma, G. E., Popa, V., Post, M., Pradier, T., Pühlhofer, G., Pulvirenti, S., Quinn, L., Raffaelli, F., Randazzo, N., Razzaque, S., Real, D., Resvanis, L., Reubelt, J., Riccobene, G., Richer, M., Rovelli, A., Salvadori, I., Samtleben, D. F. E., Sánchez Losa, A., Sanguineti, M., Santangelo, A., Sapienza, P., Schermer, B., Sciacca, V., Seneca, J., Sgura, I., Shanidze, R., Sharma, A., Simeone, F., Sinopoulou, A., Spisso, B., Spurio, M., Stavropoulos, D., Steijger, J., Stellacci, S. M., Strandberg, B., Stransky, D., Stüven, T., Taiuti, M., Tatone, F., Tayalati, Y., Tenllado, E., Thakore, T., Timmer, P., Trovato, A., Tsagkli, S., Tzamariudaki, E., Tzanetatos, D., Valieri, C., Vallage, B., Elewyck, V. Van, Versari, F., Viola, S., Vivolo, D., Volkert, M., De Waardt, L., Wilms, J., De Wolf, E., Zaborov, D., Zornoza, J. D., Zuniga, J., Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, Mollo, Carlos Maximiliano, Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPhP), KM3NeT (IHEF, IoP, FNWI), IHEF (IoP, FNWI), ATLAS (IHEF, IoP, FNWI), Akrame, S.E., Anassontzis, E.G., Coelho, J.A.B., Díaz, A.F., Fusco, L.A., Gozzini, S.R., Hernández-Rey, J.J., James, C.W., Katz, U.F., Chowdhury, N.R. Khan, Koffeman, E.N., Martínez-Mora, J.A., Melis, K.W., Miranda, L.S., Mollo, C.M., Nicolau, C.A., Pǎvǎlaş, G.E., Poma, G.E., Samtleben, D.F.E., Stellacci, S.M., and Zornoza, J.D.
Subjects: Astrofísica, Tubs, PROTOTYPE, Physics::Instrumentation and Detectors, Física::Física de partícules [Àrees temàtiques de la UPC], Particle detectors, High Tech Systems & Materials, Astrophysics, 01 natural sciences, Neutrino detector, Photon detectors for UV, visible and IR photons (vacuum), Large detector systems, Neutrino detectors, Instrumentation, KM3NeT, Photon detectors for UV, Mathematical Physics, photoelectron: yield, Physics, photomultiplier, Industrial Innovation, Peak-to-valley ratios, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Particle physics, Photodetectors, efficiency: quantum, Cherenkov counters, Cherenkov detectors, Large detector systems for particle and astroparticle physics, Dark count rate, Quantum efficiency, Física nuclear, Optoelectrònica, performance, Cherenkov detector, Cherenkov detectors, Large detector systems for particle and astroparticle physics, Neutrino detectors, Photon detectors for UV, visible and IR photons (vacuum), Instrumentation, Mathematical Physics, Photomultiplier, Fotònica, Phase (waves), Photodetector, Partícules (Física nuclear), Optics, Photo multiplier tube, 0103 physical sciences, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Optoelectronics, 010306 general physics, numerical calculations, Particles (Nuclear physics), Astroparticle physics, 010308 nuclear & particles physics, business.industry, Herenkov detectors, visible and IR photons (vacuum), Photomultipliers, Photonics, FISICA APLICADA, Large detector systems for particle and astroparticle physic, Òptica -- Aparells i instruments, Neutrino telescopes, Photon detectors for UV,visible and IR photons (vacuum), business, Telescopes
Abstract: [EN] The Hamamatsu R12199-02 3-inch photomultiplier tube is the photodetector chosen for the first phase of the KM3NeT neutrino telescope. About 7000 photomultipliers have been characterised for dark count rate, timing spread and spurious pulses. The quantum eÿciency, the gain and the peak-to-valley ratio have also been measured for a sub-sample in order to determine parameter values needed as input to numerical simulations of the detector., The authors acknowledge the financial support of the funding agencies: Agence Nationale de la Recherche (contract ANR-15-CE31-0020), Centre National de la Recherche Scientifique (CNRS), Commission Europeenne (FEDER fund and Marie Curie Program), Institut Universitaire de France (IUF), IdEx program and UnivEarthS Labex program at Sorbonne Paris Cite (ANR-10-LABX-0023 and ANR-11-IDEX-0005-02), France; 'Helmholtz Alliance for Astroparticle Physics' funded by the Initiative and Networking Fund of the Helmholtz Association, Germany; The General Secretariat of Research and Technology (GSRT), Greece; Istituto Nazionale di Fisica Nucleare (INFN), Ministero dell'Istruzione, dell'Universita e della Ricerca (MIUR), Italy; Agence de l'Oriental and CNRST, Morocco; Nederlandse organisatie voor Wetenschappelijk Onderzoek (NWO), the Netherlands; National Authority for Scientific Research (ANCS), Romania; Plan Estatal de Investigacion (refs. FPA2015-65150-C3-1-P, -2-P and -3-P, (MINECO/FEDER)), Severo Ochoa Centre of Excellence and MultiDark Consolider (MINECO), and Prometeo and Grisolia programs (Generalitat Valenciana), Spain.
Published: 2018

44. An algorithm for the reconstruction of neutrino-induced showers in the ANTARES Neutrino telescope

Author: Alba Domi, A. Vizzoca, V. Popa, Steffen Hallmann, Daniele Vivolo, Matthias Kadler, T. Grégoire, C. W. James, M. Ardid, R. Coniglione, Kay Graf, Karel Melis, R. Gracia Ruiz, T. Michael, L. Quinn, O. Kalekin, A. Enzenhöfer, J-J. Aubert, D. Kießling, C. Hugon, M. Organokov, A. Albert, Alessia Capone, D. Dornic, G. De Bonis, J. Hofestädt, V. Bertin, Ivan Felis, Vladimir Kulikovskiy, J.D. Zornoza, S. Loucatos, M. Saldaña, Federico Versari, M. Kreter, R. Mele, J. Barrios-Martí, Yahya Tayalati, Jürgen Brunner, Dominique Lefèvre, Gisela Anton, I. Di Palma, G.E. Păvălaş, Antonio F. Díaz, Jose Busto, Dominik Elsässer, J. Zúñiga, A. Sánchez-Losa, Farida Fassi, F. Schüssler, A. Ettahiri, Bruny Baret, Alexis Coleiro, P. Piattelli, Annarita Margiotta, Tommaso Chiarusi, Michel André, I. El Bojaddaini, Joao A B Coelho, S.F. Biagi, B. Vallage, Corinne Donzaud, S. Navas, A. Creusot, P. Migliozzi, S. Bourret, T. Avgitas, Hervé Glotin, V. Van Elewyck, M. Jongen, E. Nezri, C. Tönnis, J. Carr, Luigi Antonio Fusco, Yann Hello, C. Racca, I. Salvadori, C. Distefano, D. F. E. Samtleben, Maurizio Spurio, C. Perrina, M. Taiuti, M. Marcelin, R. Bruijn, A.J. Heijboer, Th. Stolarczyk, Antoine Kouchner, Anne Deschamps, Robert Lahmann, H. van Haren, D. Drouhin, Thierry Pradier, B. Belhorma, Matteo Sanguineti, G. Riccobene, Giulia Illuminati, C. Lachaud, Silvia Celli, P. Coyle, R. Cherkaoui El Moursli, Abdelilah Moussa, I. Kreykenbohm, Thomas Eberl, M. Lotze, J. Hößl, C. Sieger, H. Brânzaş, V. Giordano, S. Basa, Jörn Wilms, M. de Jong, C. Pellegrino, M. Circella, U. Katz, M. Anghinolfi, N. El Khayati, Emanuele Leonora, A. Trovato, D. Turpin, A. Marinelli, Juan José Hernández-Rey, M.C. Bouwhuis, R. Bormuth, Paolo Sapienza, Heide Costantini, J.A. Martínez-Mora, L. Caramete, Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, Centre de Physique des Particules de Marseille ( CPPM ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Aix Marseille Université ( AMU ), AstroParticule et Cosmologie ( APC - UMR 7164 ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ), Laboratoire d'Astrophysique de Marseille ( LAM ), Aix Marseille Université ( AMU ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National d'Etudes Spatiales ( CNES ) -Centre National de la Recherche Scientifique ( CNRS ), Géoazur ( GEOAZUR ), Université Nice Sophia Antipolis ( UNS ), Université Côte d'Azur ( UCA ) -Université Côte d'Azur ( UCA ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Observatoire de la Côte d'Azur, Université Côte d'Azur ( UCA ) -Centre National de la Recherche Scientifique ( CNRS ), Université Paris-Sud - Paris 11 ( UP11 ), Laboratoire de Physique de Clermont ( LPC ), Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Université Clermont Auvergne ( UCA ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire des Sciences de l'Information et des Systèmes ( LSIS ), Aix Marseille Université ( AMU ) -Université de Toulon ( UTLN ) -Arts et Métiers Paristech ENSAM Aix-en-Provence-Centre National de la Recherche Scientifique ( CNRS ), Institut méditerranéen d'océanologie ( MIO ), Centre National de la Recherche Scientifique ( CNRS ) -Université de Toulon ( UTLN ) -Aix Marseille Université ( AMU ) -Institut de Recherche pour le Développement ( IRD ), Département de Physique des Particules (ex SPP) ( DPP ), Institut de Recherches sur les lois Fondamentales de l'Univers ( IRFU ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay, Institut Pluridisciplinaire Hubert Curien ( IPHC ), Centre National de la Recherche Scientifique ( CNRS ) -Université de Strasbourg ( UNISTRA ), ANTARES, Groupe de Recherche en Physique des Hautes Energies (GRPHE), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut Universitaire de Technologie de Colmar, Centre de Physique des Particules de Marseille (CPPM), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Astrophysique de Marseille (LAM), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Aix Marseille Université (AMU)-Centre National d'Études Spatiales [Toulouse] (CNES), Géoazur (GEOAZUR 7329), Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA), Université Paris-Sud - Paris 11 (UP11), Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Clermont Auvergne (UCA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire des Sciences de l'Information et des Systèmes (LSIS), Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Arts et Métiers Paristech ENSAM Aix-en-Provence-Centre National de la Recherche Scientifique (CNRS), Institut méditerranéen d'océanologie (MIO), Centre National de la Recherche Scientifique (CNRS)-Université de Toulon (UTLN)-Aix Marseille Université (AMU)-Institut de Recherche pour le Développement (IRD), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-IUT de Colmar, Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPhP), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), KM3NeT (IHEF, IoP, FNWI), Albert, A., Andre, M., Anghinolfi, M., Anton, G., Ardid, M., Aubert, J. -J., Avgitas, T., Baret, B., Barrios-Marti, J., Basa, S., Belhorma, B., Bertin, V., Biagi, S., Bormuth, R., Bourret, S., Bouwhuis, M. C., Branzas, H., Bruijn, R., Brunner, J., Busto, J., Capone, A., Caramete, L., Carr, J., Celli, S., El Moursli, R. C., Chiarusi, T., Circella, M., Coelho, J. A. B., Coleiro, A., Coniglione, R., Costantini, H., Coyle, P., Creusot, A., Diaz, A. F., Deschamps, A., Bonis, G. D., Distefano, C., Palma, I. D., Domi, A., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., Bojaddaini, I. E., Khayati, N. E., Elsasser, D., Enzenhofer, A., Ettahiri, A., Fassi, F., Felis, I., Fusco, L. A., Gay, P., Giordano, V., Glotin, H., Gregoire, T., Ruiz, R. G., Graf, K., Hallmann, S., Haren, H. V., Heijboer, A. J., Hello, Y., Hernandez-Rey, J. J., Hossl, J., Hofestadt, J., Hugon, C., Illuminati, G., James, C. W., De Jong, M., Jongen, M., Kadler, M., Kalekin, O., Katz, U., Kiessling, D., Kouchner, A., Kreter, M., Kreykenbohm, I., Kulikovskiy, V., Lachaud, C., Lahmann, R., Lefevre, D., Leonora, E., Lotze, M., Loucatos, S., Marcelin, M., Margiotta, A., Marinelli, A., Martinez-Mora, J. A., Mele, R., Melis, K., Michael, T., Migliozzi, P., Moussa, A., Navas, S., Nezri, E., Organokov, M., Pavalas, G. E., Pellegrino, C., Perrina, C., Piattelli, P., Popa, V., Pradier, T., Quinn, L., Racca, C., Riccobene, G., Sanchez-Losa, A., Saldana, M., Salvadori, I., Samtleben, D. F. E., Sanguineti, M., Sapienza, P., Schussler, F., Sieger, C., Spurio, M., Stolarczyk, T., Taiuti, M., Tayalati, Y., Trovato, A., Turpin, D., Tonnis, C., Vallage, B., Elewyck, V. V., Versari, F., Vivolo, D., Vizzoca, A., Wilms, J., Zornoza, J. D., Zuniga, J., Andrã©, M., Branzaå , H., El Moursli, R. Cherkaoui, G. De, Boni, I. Di, Palma, Bojaddaini, I. El, Khayati, N. El, Enzenhã¶fer, A., Grã©goire, T., Ruiz, R. Gracia, Haren, H. Van, HernÃ¡ndez-Rey, J. J., Hã¶ã l, J., Kieã ling, D., Pç vç laå , G. E., SÃ¡nchez-Losa, A., M., Saldana, Schã¼ssler, F., Stolarczyk, Th., Tã¶nnis, C., Elewyck, V. Van, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Centre National de la Recherche Scientifique (CNRS)-Arts et Métiers Paristech ENSAM Aix-en-Provence-Université de Toulon (UTLN)-Aix Marseille Université (AMU), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut Universitaire de Technologie de Colmar-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Toulon (UTLN), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Albert, A, Andre, M, Anghinolfi, M, Anton, G, Ardid, M, Aubert, Jj, Avgitas, T, Baret, B, Barrios-Marti, J, Basa, S, Belhorma, B, Bertin, V, Biagi, S, Bormuth, R, Bourret, S, Bouwhuis, Mc, Branzas, H, Bruijn, R, Brunner, J, Busto, J, Capone, A, Caramete, L, Carr, J, Celli, S, El Moursli, Rc, Chiarusi, T, Circella, M, Coelho, Jab, Coleiro, A, Coniglione, R, Costantini, H, Coyle, P, Creusot, A, Diaz, Af, Deschamps, A, De Bonis, G, Distefano, C, Di Palma, I, Domi, A, Donzaud, C, Dornic, D, Drouhin, D, Ebert, T, El Bojaddaini, I, El Khayati, N, Elsasser, D, Enzenhofer, A, Ettahiri, A, Fassi, F, Felis, I, Fusco, La, Gay, P, Giordano, V, Glotin, H, Gregoire, T, Ruiz, Rg, Graf, K, Hallmann, S, van Haren, H, Heijboer, Aj, Hello, Y, Hernandez-Rey, Jj, Hossl, J, Hofestadt, J, Hugon, C, Illuminati, G, James, Cw, de Jong, M, Jongen, M, Kadler, M, Kalekin, O, Katz, U, Kiessling, D, Kouchner, A, Kreter, M, Kreykenbohm, I, Kulikovskiy, V, Lachaud, C, Lahmann, R, Lefevre, D, Leonora, E, Lotze, M, Loucatos, S, Marcelin, M, Margiotta, A, Marinelli, A, Martinez-Mora, Ja, Mele, R, Melis, K, Michael, T, Migliozzi, P, Moussa, A, Navas, S, Nezri, E, Organokov, M, Pavalas, Ge, Pellegrino, C, Perrina, C, Piattelli, P, Popa, V, Pradier, T, Quinn, L, Racca, C, Riccobene, G, Sanchez-Losa, A, Saldana, M, Salvadori, I, Samtleben, Dfe, Sanguineti, M, Sapienza, P, Schussler, F, Sieger, C, Spurio, M, Stolarczyk, T, Taiuti, M, Tayalati, Y, Trovato, A, Turpin, D, Tonnis, C, Vallage, B, Van Elewyck, V, Versari, F, Vivolo, D, Vizzoca, A, Wilms, J, Zornoza, Jd, Zuniga, J, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), and Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)
Subjects: Astrofísica, neutrinos, telescopes, ANTARES, Photon, Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, Algorismes, showers: hadronic, telescope, 01 natural sciences, neutrino: flux, neutrino, 010303 astronomy & astrophysics, [ PHYS.PHYS.PHYS-INS-DET ] Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Charged current, neutrino: interaction, Physics, photon, Astrophysics::Instrumentation and Methods for Astrophysics, Instrumentation and Detectors (physics.ins-det), charged particle, Algorithm, long-range, neutrino: detector, Neutrino detector, electron: interaction, Neutrino, Astrophysics - Instrumentation and Methods for Astrophysics, neutral current, Astrophysics::High Energy Astrophysical Phenomena, water, FOS: Physical sciences, neutrino: energy, neutrino: spectrum, 0103 physical sciences, showers: electromagnetic, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Neutrins, Neutrinos, Instrumentation and Methods for Astrophysics (astro-ph.IM), Cherenkov radiation, Muon, Neutral current, 010308 nuclear & particles physics, nucleus, muon: detector, High Energy Physics::Phenomenology, Astronomy and Astrophysics, Astronomy and Astrophysic, radiation: Cherenkov, Space and Planetary Science, Neutrino astrophysics, detector: sensitivity, angular resolution, Física::Astronomia i astrofísica [Àrees temàtiques de la UPC], High Energy Physics::Experiment, tau: decay, Lepton, Telescopes
Abstract: Muons created by $\nu_\mu$ charged current (CC) interactions in the water surrounding the ANTARES neutrino telescope have been almost exclusively used so far in searches for cosmic neutrino sources. Due to their long range, highly energetic muons inducing Cherenkov radiation in the water are reconstructed with dedicated algorithms that allow the determination of the parent neutrino direction with a median angular resolution of about \unit{0.4}{\degree} for an $E^{-2}$ neutrino spectrum. In this paper, an algorithm optimised for accurate reconstruction of energy and direction of shower events in the ANTARES detector is presented. Hadronic showers of electrically charged particles are produced by the disintegration of the nucleus both in CC and neutral current (NC) interactions of neutrinos in water. In addition, electromagnetic showers result from the CC interactions of electron neutrinos while the decay of a tau lepton produced in $\nu_\tau$ CC interactions will in most cases lead to either a hadronic or an electromagnetic shower. A shower can be approximated as a point source of photons. With the presented method, the shower position is reconstructed with a precision of about \unit{1}{\metre}, the neutrino direction is reconstructed with a median angular resolution between \unit{2}{\degree} and \unit{3}{\degree} in the energy range of \SIrange{1}{1000}{TeV}. In this energy interval, the uncertainty on the reconstructed neutrino energy is about \SIrange{5}{10}{\%}. The increase in the detector sensitivity due to the use of additional information from shower events in the searches for a cosmic neutrino flux is also presented.
Published: 2017

45. Clinical and pathological features of metastatic adenocarcinoma of the prostate to the ileum

Author: Stefan Koch, Steffen Hallmann, Jürgen Ruttloff, and Thorsten H. Ecke
Subjects: Pathology, medicine.medical_specialty, Ileus, business.industry, Metastatic adenocarcinoma, Ileum, Case Report, General Medicine, metastatsis, medicine.disease, prostate cancer, digestive system, Metastasis, Resection, Prostate cancer, medicine.anatomical_structure, Prostate, medicine, ileum, business, Pathological
Abstract: We present a case of a 74-year-old white male with a history of prostate cancer with unusual metastasis to the ileum, and with ileus as a very unusual first symptom of prostate cancer. This patient presented to us with histologically confirmed metastasis of the ileum after resection in the Department of Surgery.
Published: 2014

46. Tau neutrino appearance with KM3NeT/ORCA

Author: Steffen Hallmann, J. Hofestädt, and Thomas Eberl
Subjects: Physics, Particle physics, Muon, Unitarity, Physics::Instrumentation and Detectors, Astrophysics::High Energy Astrophysical Phenomena, High Energy Physics::Phenomenology, Astrophysics::Instrumentation and Methods for Astrophysics, Electron, KM3NeT, Neutrino detector, Tau neutrino, High Energy Physics::Experiment, Neutrino, Neutrino oscillation
Abstract: KM3NeT/ORCA is a mega-ton volume neutrino detector and has entered the construction phase in the Mediterranean Sea. Optimised to study neutrino oscillations in the few GeV energy range, it has unprecedented sensitivity to oscillations of atmospheric muon and electron neutrinos into the tau neutrino channel. Tau neutrinos predominantly produce shower-like signatures, which can be identified on a statistical basis as an energy- and direction-dependent excess over the non-appearance hypothesis. The contribution shows that the KM3NeT/ORCA detector will be able to exclude non-appearance already in the first months of data taking. In the longer run precise measurement of the tau normalisation will allow to put constraints on the commonly assumed unitarity of three neutrino mixing.
Published: 2017

47. Neutrinos from the Fermi Bubbles with ANTARES

Author: Thomas Eberl and Steffen Hallmann
Subjects: Physics, Nuclear physics, Muon, Neutrino detector, Neutral current, Astrophysics::High Energy Astrophysical Phenomena, High Energy Physics::Phenomenology, Galactic Center, Hadron, High Energy Physics::Experiment, Neutrino, Charged current, Fermi Gamma-ray Space Telescope
Abstract: The Fermi Bubbles are giant lobe-shaped structures of $\gamma$-ray emission extending above and below the Galactic Center. A variety of both hadronic and leptonic models has been proposed to explain the emission, yet its origin remains unclear. Only in hadronic scenarios, the $\gamma$-ray flux is accompanied by an associated neutrino flux that might be detected with large volume neutrino detectors. ANTARES is the largest neutrino telescope in the Northern Hemisphere and has been operated in its final configuration since 2008. Its location in the Mediterranean sea provides an excellent view towards the Fermi Bubbles' region. In a previous analysis ANTARES has observed a non-significant excess of neutrinos in the Fermi Bubble region using charged current interactions of $\nu_\mu$. For these events, the outgoing muon produces an elongated track-like signature that can be reconstructed with sub-degree angular resolution. More recently, improved shower reconstruction algorithms achieve a precision of $\sim3^{\circ}$ also for signatures produced in $\nu_e$, $\nu_\tau$ and neutral current interactions. This contribution presents the search for shower-like events from the Fermi Bubbles in ANTARES data. In combination with the previous analysis, upper limits on the all-flavour neutrino emission from the region are derived.
Published: 2017

48. Search for high-energy neutrinos from bright GRBs with ANTARES

Author: Jörn Wilms, A. Gleixner, Th. Stolarczyk, A. Marinelli, M.C. Bouwhuis, H. van Haren, R. Bormuth, Bruny Baret, M. Anghinolfi, M. de Jong, S. Wagner, G. Illuminati, Dominique Lefèvre, Emanuele Leonora, Michel André, S.F. Biagi, A. Mathieu, Jose Busto, J.A. Martínez-Mora, Corinne Donzaud, Dominik Elsässer, Hervé Glotin, V. Van Elewyck, Robert Lahmann, C. Tönnis, D. Drouhin, J. Zúñiga, D. Turpin, Anne Deschamps, M. Saldaña, C. Racca, Paolo Sapienza, Joao A B Coelho, M. Taiuti, Uli Katz, L. Caramete, P. Coyle, Antoine Kouchner, H. Costantini, I. Kreykenbohm, Annarita Margiotta, M. Ardid, A. Trovato, Kay Graf, Matteo Sanguineti, R. Mele, Karel Melis, E. Nezri, O. Kalekin, Maria Tselengidou, T. Seitz, G. Riccobene, Thierry Pradier, S. Basa, Jutta Schnabel, Daniele Vivolo, G. De Bonis, Antonio Capone, A. Enzenhöfer, Maurizio Spurio, C. Pellegrino, J. Barrios-Martí, A. Albert, F. Schüssler, C. Mueller, A.J. Heijboer, T. Grégoire, Damien Dornic, V. Bertin, R. Bruijn, I. El Bojaddaini, Ivan Felis, J. Brunner, P. Migliozzi, I. Salvadori, L. Quinn, T. Avgitas, S. Geißelsöder, M. Kreter, Gisela Anton, P. Piattelli, R. Coniglione, V. Popa, Silvia Celli, J.J. Hernández-Rey, Yahya Tayalati, C. Perrina, D. Kießling, Y. Hello, K. Roensch, J. Hofestädt, Steffen Hallmann, Abdelilah Moussa, R. Gracia-Ruiz, Matthias Kadler, Tommaso Chiarusi, M. Jongen, C. Distefano, K. Geyer, Thomas Eberl, A. Creusot, D. F. E. Samtleben, M. Lotze, J-J. Aubert, J.D. Zornoza, S. Loucatos, T. Michael, A. Sánchez-Losa, C. Hugon, Alexis Coleiro, G.E. Păvălaş, I. Di Palma, B. Vallage, J. Carr, Luigi Antonio Fusco, M. Marcelin, S. Bourret, C. W. James, C. Vallée, A. Vizzocca, V. Giordano, S. Galatà, M. Circella, Vladimir Kulikovskiy, J. Hößl, C. Sieger, C. Lachaud, Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Géoazur (GEOAZUR 7329), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Institut méditerranéen d'océanologie (MIO), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Albert, A., Andrã©, M., Anghinolfi, M., Anton, G., Ardid, M., Aubert, J. -. J., Avgitas, T., Baret, B., Barrios-MartÃ, J., Basa, S., Bertin, V., Biagi, S., Bormuth, R., Bourret, S., Bouwhuis, M. C., Bruijn, R., Brunner, J., Busto, J., Capone, A., Caramete, L., Carr, J., Celli, S., Chiarusi, T., Circella, M., Coelho, J. A. B., Coleiro, A., Coniglione, R., Costantini, H., Coyle, P., Creusot, A., Deschamps, A., De Bonis, G., Distefano, C., Di Palma, I., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., El Bojaddaini, I., Elsã¤sser, D., Enzenhã¶fer, A., Felis, I., Fusco, L. A., Galatã , S., Gay, P., Geiã elsã¶der, S., Geyer, K., Giordano, V., Gleixner, A., Glotin, H., Gregoire, T., Gracia-Ruiz, R., Graf, K., Hallmann, S., van Haren, H., Heijboer, A. J., Hello, Y., HernÃ¡ndez-Rey, J. J., Hã¶ã l, J., Hofestã¤dt, J., Hugon, C., Illuminati, G., James, C. W., de Jong, M., Jongen, M., Kadler, M., Kalekin, O., Katz, U., Kieã ling, V., Kouchner, A., Kreter, M., Kreykenbohm, I., Kulikovskiy, V., Lachaud, C., Lahmann, R., Lefãvre, D., Leonora, E., Lotze, M., Loucatos, S., Marcelin, M., Margiotta, A., Marinelli, A., MartÃnez-Mora, J. A., Mathieu, A., Mele, R., Melis, K., Michael, T., Migliozzi, P., Moussa, A., Mueller, C., Nezri, E., Pä vä laå , G. E., Pellegrino, C., Perrina, C., Piattelli, P., Popa, V., Pradier, T., Quinn, L., Racca, C., Riccobene, G., Roensch, K., SÃ¡nchez-Losa, A., Saldaã±a, M., Salvadori, I., Samtleben, D. F. E., Sanguineti, M., Sapienza, P., Schnabel, J., Schã¼ssler, F., Seitz, T., Sieger, C., Spurio, M., Stolarczyk, T., Taiuti, M., Tayalati, Y., Trovato, A., Tselengidou, M., Turpin, D., Tã¶nnis, C., Vallage, B., Vallã©e, C., Van Elewyck, V., Vivolo, D., Vizzocca, A., Wagner, S., Wilms, J., Zornoza, J. D., Zãºã±iga, J., Andre, M., Aubert, J. -J., Barrios-Marti, J., Elsasser, D., Enzenhofer, A., Galata, S., Geisselsoder, S., Hernandez-Rey, J. J., Hossl, J., Hofestadt, J., Kiessling, V., Lefevre, D., Martinez-Mora, J. A., Pavalas, G. E., Sanchez-Losa, A., Saldana, M., Schussler, F., Tonnis, C., Vallee, C., Zuniga, J., KM3NeT (IHEF, IoP, FNWI), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Interactions fondamentales, Astroparticules et Cosmologie (IFAC), Laboratoire Charles Coulomb (L2C), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Toulon (UTLN), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Albert, A, Andre, M, Anghinolfi, M, Anton, G, Ardid, M, Aubert, Jj, Avgitas, T, Baret, B, Barrios-Marti, J, Basa, S, Bertin, V, Biagi, S, Bormuth, R, Bourret, S, Bouwhuis, Mc, Bruijn, R, Brunner, J, Busto, J, Capone, A, Caramete, L, Carr, J, Celli, S, Chiarusi, T, Circella, M, Coelho, Jab, Coleiro, A, Coniglione, R, Costantini, H, Coyle, P, Creusot, A, Deschamps, A, De Bonis, G, Distefano, C, Di Palma, I, Donzaud, C, Dornic, D, Drouhin, D, Eberl, T, El Bojaddaini, I, Elsasser, D, Enzenhofer, A, Felis, I, Fusco, La, Galata, S, Gay, P, Geisseloder, S, Geyer, K, Giordano, V, Gleixner, A, Glotin, H, Gregoire, T, Gracia-Ruiz, R, Graf, K, Hallmann, S, van Haren, H, Heijboer, Aj, Hello, Y, Hernandez-Rey, Jj, Hossl, J, Hofestadt, J, Hugon, C, Illuminati, G, James, Cw, de Jong, M, Jongen, M, Kadler, M, Kalekin, O, Katz, U, Kieling, D, Kouchner, A, Kreter, M, Kreykenbohm, I, Kulikovskiy, V, Lachaud, C, Lahmann, R, Lefevre, D, Leonora, E, Lotze, M, Loucatos, S, Marcelin, M, Margiotta, A, Marinelli, A, Martinez-Mora, Ja, Mathieu, A, Mele, R, Melis, K, Michael, T, Migliozzi, P, Moussa, A, Mueller, C, Nezri, E, Pavalas, Ge, Pellegrino, C, Perrina, C, Piattelli, P, Popa, V, Pradier, T, Quinn, L, Racca, C, Riccobene, G, Roensch, K, Sanchez-Losa, A, Saldana, M, Salvadori, I, Samtleben, Dfe, Sanguineti, M, Sapienza, P, Schnabel, J, Schussler, F, Seitz, T, Sieger, C, Spurio, M, Stolarczyk, T, Taiuti, M, Tayalati, Y, Trovato, A, Tselengidou, M, Turpin, D, Tonnis, C, Vallage, B, Vallee, C, Van Elewyck, V, Vivolo, D, Vizzocca, A, Wagner, S, Wilms, J, Zornoza, Jd, and Zuniga, J
Subjects: Astrofísica, Acceleration of particles, Physics::Instrumentation and Detectors, Solar neutrino, Astrophysics, 7. Clean energy, 01 natural sciences, individual: GRB 130427A [Gamma-ray burst], Gamma-ray burst: individual: GRB 110918A, 010303 astronomy & astrophysics, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), Acceleradors de partícules, individual: GRB 080916C [Gamma-ray burst], neutrinos, Acceleration of particle, Neutrino detector, Measurements of neutrino speed, Neutrino, Astrophysics - High Energy Astrophysical Phenomena, Gamma-ray burst: individual: GRB 080916C - gamma-ray burst: individual: GRB 110918A, Gamma-ray burst: individual: GRB 130427A - gamma-ray burst: individual: GRB 130505A, Neutrinos, [PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, acceleration of particles, gamma-ray burst: individual: GRB 080916C, gamma-ray burst: individual: GRB 110918A, gamma-ray burst: individual: GRB 130427A, gamma-ray burst: individual: GRB 130505A, 0103 physical sciences, Gamma-ray burst: individual: GRB 130505A, Neutrins, Astronomy and Astrophysics, Space and Planetary Science, 010306 general physics, individual: GRB 130505A [Gamma-ray burst], High Energy Physics::Phenomenology, GRB 130427A, Astronomy, Solar neutrino problem, Astronomy and Astrophysic, Neutrino astrophysics, 13. Climate action, Gamma-ray burst: individual: GRB 130427A, FISICA APLICADA, Física::Astronomia i astrofísica [Àrees temàtiques de la UPC], High Energy Physics::Experiment, Gamma-ray burst: individual: GRB 080916C, Neutrino astronomy, Gamma-ray burst, individual: GRB 110918A [Gamma-ray burst]
Abstract: [EN] Gamma-ray bursts are thought to be sites of hadronic acceleration, thus neutrinos are expected from the decay of charged particles, produced in p gamma interactions. The methods and results of a search for muon neutrinos in the data of the ANTARES neutrino telescope from four bright GRBs (GRB 080916C, GRB 110918A, GRB 130427A and GRB 130505A) observed between 2008 and 2013 are presented. Two scenarios of the fireball model have been investigated: the internal shock scenario, leading to the production of neutrinos with energies mainly above 100 TeV, and the photospheric scenario, characterized by a low-energy component in neutrino spectra due to the assumption of neutrino production closer to the central engine. Since no neutrino events have been detected in temporal and spatial coincidence with these bursts, upper limits at 90 per cent confidence level on the expected neutrino fluxes are derived. The non-detection allows for directly constraining the bulk Lorentz factor of the jet Gamma and the baryon loading f(p), We acknowledge the financial support of the funding agencies: Centre National de la Recherche Scientifique (CNRS), Commissariat a l'energie atomique et aux energies alternatives (CEA), Commission Europeenne (FEDER fund and Marie Curie Program), Institut Universitaire de France (IUF), IdEx programme and UnivEarthS Labex programme at Sorbonne Paris Cite (ANR-10-LABX-0023 and ANR-11-IDEX-0005-02), Labex OCEVU (ANR-11-LABX-0060) and the A*MIDEX project (ANR-11-IDEX-0001-02), Region Ile-de-France (DIM-ACAV), Region Alsace (contrat CPER), Region Provence-Alpes-Cote d'Azur, Departement du Var and Ville de La Seyne-sur-Mer, France; Bundesministerium fur Bildung und Forschung (BMBF), Germany; Istituto Nazionale di Fisica Nucleare (INFN), Italy; Stichting voor Fundamenteel Onderzoek der Materie (FOM), Nederlandse organisatie voor Wetenschappelijk Onderzoek (NWO), the Netherlands; Council of the President of the Russian Federation for young scientists and leading scientific schools supporting grants, Russia; National Authority for Scientific Research (ANCS), Romania; Ministerio de Economia y Competitividad (MINECO): Plan Estatal de Investigacion (refs. FPA2015-65150-C3-1-P, -2-P and -3-P, (MINECO/FEDER)), Severo Ochoa Centre of Excellence and MultiDark Consolider (MINECO), and Prometeo and Grisolia programmes (Generalitat Valenciana), Spain; Agence de l'Oriental and CNRST, Morocco. We also acknowledge the technical support of Ifremer, AIM and Foselev Marine for the sea operation and the CC-IN2P3 for the computing facilities
Published: 2017

49. Search for Dark Matter Annihilation in the Earth using the ANTARES Neutrino Telescope

Author: A. Enzenhöfer, E. Nezri, C. Mueller, R. Bruijn, M. Kreter, Gisela Anton, C. Vallée, V. Giordano, I. Di Palma, S. Basa, S. Galatà, A. Trovato, M. de Jong, Vladimir Kulikovskiy, B. Vallage, Silvia Celli, C. Pellegrino, V. Popa, A. Gleixner, V. Bertin, Maria Tselengidou, D. Kießling, Ivan Felis, Steffen Hallmann, Dominique Lefèvre, T. Seitz, K. Geyer, M. Saldaña, Thomas Eberl, J-J. Aubert, M. Lotze, C. Tönnis, C. Racca, J.D. Zornoza, C. Hugon, P. Piattelli, G. Illuminati, S. Loucatos, J. Barrios-Martí, G. De Bonis, O. Kalekin, Antoine Kouchner, Anne Deschamps, S. Wagner, R. Mele, S. Geißelsöder, Daniele Vivolo, Matteo Sanguineti, G.E. Păvălaş, F. Schüssler, A. Vizzoca, Kay Graf, Karel Melis, G. Riccobene, M. Jongen, Dominik Elsässer, M. Circella, A. Sánchez-Losa, C. Distefano, D. F. E. Samtleben, Matthias Kadler, T. Grégoire, P. Migliozzi, P. Coyle, M. Taiuti, T. Avgitas, Alexis Coleiro, Emanuele Leonora, L. Caramete, R. Gracia Ruiz, T. Michael, A. Creusot, Jutta Schnabel, Jörn Wilms, A. Mathieu, Abdelilah Moussa, Thierry Pradier, J. Hößl, L. Quinn, C. Sieger, J. Carr, Luigi Antonio Fusco, C. W. James, M. Marcelin, M. Ardid, J. Brunner, A. Albert, M. Anghinolfi, J.J. Hernández-Rey, Yahya Tayalati, Y. Hello, K. Roensch, D. Turpin, S.F. Biagi, S. Bourret, Corinne Donzaud, I. Salvadori, Antonio Capone, Maurizio Spurio, A.J. Heijboer, R. Coniglione, Jose Busto, J. Hofestädt, Tommaso Chiarusi, J. Zúñiga, Joao A B Coelho, I. Kreykenbohm, Th. Stolarczyk, H. van Haren, Robert Lahmann, D. Drouhin, Uli Katz, Annarita Margiotta, Bruny Baret, Michel André, Hervé Glotin, V. Van Elewyck, C. Lachaud, Damien Dornic, C. Perrina, A. Marinelli, M.C. Bouwhuis, R. Bormuth, I. El Bojaddaini, Paolo Sapienza, Heide Costantini, J.A. Martínez-Mora, KM3NeT (IHEF, IoP, FNWI), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Antares Collaboration, Centre Tecnològic de Vilanova i la Geltrú, Universitat Politècnica de Catalunya. LAB - Laboratori d'Aplicacions Bioacústiques, Albert, A., Andre, M., Anghinolfi, M., Anton, G., Ardid, M., Aubert, J. -J., Avgitas, T., Baret, B., Barrios-Marti, J., Basa, S., Bertin, V., Biagi, S., Bormuth, R., Bourret, S., Bouwhuis, M. C., Bruijn, R., Brunner, J., Busto, J., Capone, A., Caramete, L., Carr, J., Celli, S., Chiarusi, T., Circella, M., Coelho, J. A. B., Coleiro, A., Coniglione, R., Costantini, H., Coyle, P., Creusot, A., Deschamps, A., De Bonis, G., Distefano, C., Di Palma, I., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., El Bojaddaini, I., Elsasser, D., Enzenhofer, A., Felis, I., Fusco, L. A., Galata, S., Gay, P., Geisselsoder, S., Geyer, K., Giordano, V., Gleixner, A., Glotin, H., Gregoire, T., Gracia Ruiz, R., Graf, K., Hallmann, S., van Haren, H., Heijboer, A. J., Hello, Y., Hernandez-Rey, J. J., Hossl, J., Hofestadt, J., Hugon, C., Illuminati, G., James, C. W., de Jong, M., Jongen, M., Kadler, M., Kalekin, O., Katz, U., Kiessling, D., Kouchner, A., Kreter, M., Kreykenbohm, I., Kulikovskiy, V., Lachaud, C., Lahmann, R., Lefevre, D., Leonora, E., Lotze, M., Loucatos, S., Marcelin, M., Margiotta, A., Marinelli, A., Martinez-Mora, J. A., Mathieu, A., Mele, R., Melis, K., Michael, T., Migliozzi, P., Moussa, A., Mueller, C., Nezri, E., Pavalas, G. E., Pellegrino, C., Perrina, C., Piattelli, P., Popa, V., Pradier, T., Quinn, L., Racca, C., Riccobene, G., Roensch, K., Sanchez-Losa, A., Saldana, M., Salvadori, I., Samtleben, D. F. E., Sanguineti, M., Sapienza, P., Schnabel, J., Schussler, F., Seitz, T., Sieger, C., Spurio, M., Stolarczyk, T., Taiuti, M., Tayalati, Y., Trovato, A., Tselengidou, M., Turpin, D., Tonnis, C., Vallage, B., Vallee, C., Van Elewyck, V., Vivolo, D., Vizzoca, A., Wagner, S., Wilms, J., Zornoza, J. D., Zuniga, J., André, M., Aubert, J.-J., Barrios-Martí, J., Bouwhuis, M.C., Coelho, J.A.B., De bonis, G., Di palma, I., Elsässer, D., Enzenhöfer, A., Fusco, L.A., Galatà, S., Geißelsöder, S., Grégoire, T., Gracia ruiz, R., Van haren, H., Heijboer, A.J., Hernández-Rey, J.J., Hößl, J., Hofestädt, J., James, C.W., De jong, M., Kießling, D., Lefèvre, D., Martínez-Mora, J.A., Păvălaş, G.E., Sánchez-Losa, A., Saldaña, M., Samtleben, D.F.E., Schüssler, F., Stolarczyk, Th., Tönnis, C., Vallée, C., Van elewyck, V., Zornoza, J.D., Zúñiga, J., Albert, A, Andre, M, Anghinolfi, M, Anton, G, Ardid, M, Aubert, Jj, Avgitas, T, Baret, B, Barrios-Marti, J, Basa, S, Bertin, V, Biagi, S, Bormuth, R, Bourret, S, Bouwhuis, Mc, Bruijn, R, Brunner, J, Busto, J, Capone, A, Caramete, L, Carr, J, Celli, S, Chiarusi, T, Circella, M, Coelho, Ab, Coleiro, A, Coniglione, R, Costantini, H, Coyle, P, Creusot, A, Deschamps, A, De Bonis, G, Distefano, C, Di Palma, I, Donzaud, C, Dornic, D, Drouhin, D, Eberl, T, El Bojaddaini, I, Elsasser, D, Enzenhofer, A, Felis, I, Fusco, La, Galata, S, Gay, P, Geisselsoder, S, Geyer, K, Giordano, V, Gleixner, A, Glotin, H, Gregoire, T, Ruiz, Rg, Graf, K, Hallmann, S, van Haren, H, Heijboer, Aj, Hello, Y, Hernandez-Rey, Jj, Hossl, J, Hofestadt, J, Hugon, C, Illuminati, G, James, Cw, de Jong, M, Jongen, M, Kadler, M, Kalekin, O, Katz, U, Kiessling, D, Kouchner, A, Kreter, M, Kreykenbohm, I, Kulikovskiy, V, Lachaud, C, Lahmann, R, Lefevre, D, Leonora, E, Lotze, M, Loucatos, S, Marcelin, M, Margiotta, A, Marinelli, A, Martinez-Mora, Ja, Mathieu, A, Mele, R, Melis, K, Michael, T, Migliozzi, P, Moussa, A, Mueller, C, Nezri, E, Pavalas, Ge, Pellegrino, C, Perrina, C, Piattelli, P, Popa, V, Pradier, T, Quinn, L, Racca, C, Riccobene, G, Roensch, K, Sanchez-Losa, A, Saldana, M, Salvadori, I, Samtleben, Dfe, Sanguineti, M, Sapienza, P, Schnabel, J, Schussler, F, Seitz, T, Sieger, C, Spurio, M, Stolarczyk, T, Taiuti, M, Tayalati, Y, Trovato, A, Tselengidou, M, Turpin, D, Tonnis, C, Vallage, B, Vallee, C, Van Elewyck, V, Vivolo, D, Vizzoca, A, Wagner, S, Wilms, J, Zornoza, Jd, and Zuniga, J
Subjects: Astrofísica, Physics::Instrumentation and Detectors, Astrophysics, Neutrino telescope, 01 natural sciences, 7. Clean energy, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), ANTARES, Dark matter, Indirect detection, WIMP, Astronomy and Astrophysics, Space and Planetary Science, High Energy Physics - Phenomenology (hep-ph), [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Spin-½, Physics, Annihilation, Astrophysics::Instrumentation and Methods for Astrophysics, High Energy Physics - Phenomenology, 16 (2017) 41-48, Neutrino detector, Weakly interacting massive particles, WIMPS, neutrino telescope, ANTARES, Computer Science::Mathematical Software, Neutrino, Nucleon, Particle physics, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, Astrophysics::Cosmology and Extragalactic Astrophysics, Computer Science::Digital Libraries, Nuclear physics, 0103 physical sciences, Neutrins, Neutrinos, 010306 general physics, Telescopis, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, WINP, Neutrino astrophysics, 13. Climate action, Física::Astronomia i astrofísica [Àrees temàtiques de la UPC], FISICA APLICADA, [PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph], High Energy Physics::Experiment, Telescopes
Abstract: [EN] A search for a neutrino signal from WIMP pair annihilations in the centre of the Earth has been performed with the data collected with the ANTARES neutrino telescope from 2007 to 2012. The event selection criteria have been developed and tuned to maximise the sensitivity of the experiment to such a neutrino signal. No significant excess of neutrinos over the expected background has been observed. Upper limits at 90% C.L. on the WIMP annihilation rate in the Earth and the spin independent scattering cross-section of WIMPs to nucleons σpSI were calculated for WIMP pair annihilations into either τ +τ −, W+W−, bb- or the non-SUSY νµν¯µ as a function of the WIMP mass (between 25 GeV/c2 and 1000 GeV/c2) and as a function of the thermally averaged annihilation cross section times velocity ⟨σAv⟩Earth of the WIMPs in the centre of the Earth. For masses of the WIMP close to the mass of iron nuclei (50 GeV/c2), σpSI the obtained limits on are more stringent than those obtained by other indirect searches., The authors acknowledge the financial support of the funding agencies: Centre National de la Recherche Scientifique (CNRS), Commissariat a l'energie atomique et aux energies alternatives (CEA), Commission Europeenne (FEDER fund and Marie Curie Program), Institut Universitaire de France (IUF), IdEx program and UnivEarthS Labex program at Sorbonne Paris Cite (ANR-10-LABX-0023 and ANR-11-IDEX-0005-02), Labex OCEVU (ANR-11-LABX-0060) and the A*MIDEX project (ANR-11-IDEX-0001-02), Region Ile-de-France (DIM-ACAV), Region Alsace (contrat CPER), Region Provence-Alpes-Cote d'Azur, Departement du Var and Ville de La Seyne-sur-Mer, France; Bundesministerium fur Bildung und Forschung (BMBF), Germany; Istituto Nazionale di Fisica Nucleare (INFN), Italy; Stichting voor Fundamenteel Onderzoek der Materie (FOM), Nederlandse organisatie voor Wetenschappelijk Onderzoek (NWO), the Netherlands; Council of the President of the Russian Federation for young scientists and leading scientific schools supporting grants, Russia; National Authority for Scientific Research (ANCS), Romania; Ministerio de Economia y Competitividad (MINECO): Plan Estatal de Investigacion (refs. FPA2015-65150-C3-1-P, -2-P and -3-P, (MINECO/FEDER)), Severo Ochoa Centre of Excellence and MultiDark Consolider (MINECO), and Prometeo and Grisolia programs (Generalitat Valenciana), Spain; Ministry of Higher Education, Scientific Research and Professional Training, Morocco. We also acknowledge the technical support of Ifremer, AIM and Foselev Marine for the sea operation and the CC-IN2P3 for the computing facilities.
Published: 2017

50. UBC

Author: Thorsten H, Ecke, Sarah, Weiß, Carsten, Stephan, Steffen, Hallmann, Dimitri, Barski, Thomas, Otto, and Holger, Gerullis
Subjects: Aged, 80 and over, Male, Keratin-18, Urinary Bladder Neoplasms, Keratin-8, Biomarkers, Tumor, Humans, Female, Neoplasm Invasiveness, Middle Aged, Neoplasm Grading, Carcinoma in Situ, Aged
Abstract: UBC
Published: 2017

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