23 results on '"Spencer, Keith L."'
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2. Divergent reaction pathways in amine additions to β-lactone electrophiles. An application to β-peptide synthesis
3. Catalyzed acyl halidealdehyde cyclocondensations. New insights into the design of catalytic cross aldol reactions
4. Discovery of spirocyclic sulfonamides as potent Akt inhibitors with exquisite selectivity against PKA
5. Discovery and SAR of spirochromane Akt inhibitors
6. Discovery of pyrrolopyrimidine inhibitors of Akt
7. Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors
8. Synthesis of Akt Inhibitor Ipatasertib. Part 2. Total Synthesis and First Kilogram Scale-up
9. Synthesis of Akt Inhibitor Ipatasertib. Part 1. Route Scouting and Early Process Development of a Challenging Cyclopentylpyrimidine Intermediate
10. Discovery and Preclinical Pharmacology of a Selective ATP-Competitive Akt Inhibitor (GDC-0068) for the Treatment of Human Tumors
11. ChemInform Abstract: Catalyzed Acyl Halide-Aldehyde Cyclocondensations. New Insights into the Design of Catalytic Cross Aldol Reactions.
12. ChemInform Abstract: Enantioselective β-Amino Acid Synthesis Based on Catalyzed Asymmetric Acyl Halide-Aldehyde Cyclocondensation Reactions.
13. 3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6
14. Divergent Reaction Pathways in Amine Additions to β‐Lactone Electrophiles. An Application to β‐Peptide Synthesis.
15. ChemInform Abstract: Sequential Acyl Halide—Aldehyde Cyclocondensation and Enzymatic Resolution as a Route to Enantiomerically Enriched β‐Lactones.
16. Enantioselective -Amino Acid Synthesis Based on Catalyzed Asymmetric Acyl Halide – Aldehyde Cyclocondensation Reactions
17. Sequential Acyl Halide−Aldehyde Cyclocondensation and Enzymatic Resolution as a Route to Enantiomerically Enriched β-Lactones
18. Synthesisof Akt Inhibitor Ipatasertib. Part 2. TotalSynthesis and First Kilogram Scale-up.
19. Synthesisof Akt Inhibitor Ipatasertib. Part 1. RouteScouting and Early Process Development of a Challenging CyclopentylpyrimidineIntermediate.
20. Enantioselective β-Amino Acid Synthesis Based on Catalyzed Asymmetric Acyl Halide - Aldehyde Cyclocondensation Reactions.
21. Enantioselective -Amino Acid Synthesis Based on Catalyzed Asymmetric Acyl HalideAldehyde Cyclocondensation Reactions <FN ID="fnxx"> The National Science Foundation (CHE-9875735) and the University of Pittsburgh are gratefully acknowledged for support of this work. We thank Prof. Peter Wipf for helpful discussions during the preparation of this manuscript.</FN>
22. ChemInform Abstract: Enantioselective β-Amino Acid Synthesis Based on Catalyzed Asymmetric Acyl Halide-Aldehyde Cyclocondensation Reactions.
23. ChemInform Abstract: Catalyzed Acyl Halide-Aldehyde Cyclocondensations. New Insights into the Design of Catalytic Cross Aldol Reactions.
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