Sequential acyl halide-aldehyde cyclocondensation and enzymatic resolution as a route to enantiomerically enriched beta-lactones

Authors :: Nelson, Scott G.
Spencer, Keith L.
Source :: Journal of Organic Chemistry. Feb 25, 2000, Vol. 65 Issue 4, p1227, 4 p.
Publication Year :: 2000
Abstract: Research has been conducted on the beta-lactones. The preparation of the optically active beta-lactones via enzymatic resolution of the racemic 4-substituted-2-oxetanones derived from the acyl halide-aldehyde reactions has been investigated.

Subjects :: Chemistry, Organic -- Research
Halides -- Physiological aspects
Aldehydes -- Physiological aspects
Enzymes -- Physiological aspects
Lactones -- Physiological aspects
Biological sciences
Chemistry

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