27 results on '"Soubhia AM"'
Search Results
2. Osteolipoma of the buccal mucosa
- Author
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Castro, A., primary, Castro, E., additional, Felipini, R., additional, Ribeiro, AC., additional, and Soubhia, AM, additional
- Published
- 2010
- Full Text
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3. Intermuscular lipoma of the submandibular space.
- Author
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Adachi P, Kaba SP, Soubhia AM, and Shinohara EH
- Published
- 2011
4. Efficacy of the C-terminal telopeptide test in predicting the development of bisphosphonate-related osteonecrosis of the jaw: a systematic review.
- Author
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Dal Prá KJ, Lemos CA, Okamoto R, Soubhia AM, and Pellizzer EP
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- Humans, Predictive Value of Tests, Risk Factors, Tooth Extraction adverse effects, Bisphosphonate-Associated Osteonecrosis of the Jaw blood, Collagen Type I blood, Peptides blood
- Abstract
This systematic review evaluated the efficacy of the morning fasting serum C-terminal telopeptide (CTX) test in predicting the development of bisphosphonate-related osteonecrosis of the jaw (BRONJ). A comprehensive search of studies published up to March 2016, and listed in the PubMed/MEDLINE, Web of Science, and Cochrane Library databases, was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. This review has been registered in the PROSPERO international prospective register of systematic reviews (CRD42016036717). The search identified 542 publications; eight studies were finally deemed eligible for inclusion according to the study criteria. These studies included a total 1442 patients (mean age 66.7 years). The most prescribed drug was alendronate, with osteoporosis being the most frequent indication for the prescription of bisphosphonates. Tooth extraction was the most common trigger for BRONJ. Of all patients evaluated after bisphosphonate treatment, only 24 (1.7%) developed BRONJ. All eight of the selected studies found that CTX levels were not predictive of the development of BRONJ. In conclusion, this systematic review indicates that the CTX test has no predictive value in determining the risk of osteonecrosis in patients taking bisphosphonates., (Copyright © 2016 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.)
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- 2017
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5. Stromal myofibroblasts in squamous cell carcinoma of the tongue in young patients - a multicenter collaborative study.
- Author
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Fonseca FP, Coletta RD, Azevedo MB, Prado Ribeiro AC, Pires Soubhia AM, Miyahara GI, Carlos R, Farthing P, Hunter KD, Speight PM, Vargas PA, Almeida OP, Lopes MA, and Santos-Silva AR
- Subjects
- Adolescent, Adult, Aged, Female, Humans, Immunoenzyme Techniques, Male, Middle Aged, Risk Factors, Carcinoma, Squamous Cell pathology, Myofibroblasts pathology, Tongue Neoplasms pathology
- Abstract
Objective: The purpose of this study was to evaluate the presence of myofibroblasts, frequently associated with a more aggressive neoplastic behavior, in oral tongue squamous cell carcinoma (TSCC) of young patients and to compare with the distribution observed in older patients., Study Design: Tumor samples from 29 patients younger than 40 years old affected by TSCC were retrieved and investigated for the presence of stromal myofibroblasts by immunohistochemical reactions against α smooth muscle actin, and the results obtained were compared to TSCC cases affecting older patients., Results: No positive reaction could be found in the stromal areas devoid of neoplastic tissue, whereas myofibroblasts were present in 58.6% of the lesions in young patients and in 75.9% of the older ones. No significant difference was found when comparing the invasive front and the overall stroma of both groups, and no correlation could be obtained with stromal α smooth muscle actin expression, higher tumor grades or clinical stage (P > .05)., Conclusion: There was no significant difference between the presence of stromal myofibroblasts of TSCC affecting young and old individuals., (Copyright © 2014 Elsevier Inc. All rights reserved.)
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- 2014
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6. Cementoblastoma: a case report in deciduous tooth.
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Monti LM, Souza AM, Soubhia AM, Jorge WA, Anichinno M, and Da Fonseca GL
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- Biopsy, Child, Female, Humans, Mandibular Neoplasms pathology, Mandibular Neoplasms surgery, Odontogenic Tumors pathology, Odontogenic Tumors surgery, Radiography, Panoramic, Tomography, X-Ray Computed, Tooth Root pathology, Tooth Root surgery, Dental Cementum pathology, Mandibular Neoplasms diagnosis, Odontogenic Tumors diagnosis, Tooth, Deciduous pathology, Tooth, Deciduous surgery
- Abstract
Background: The benign cementoblastoma is an odontogenic tumor originated from neoplastic cementoblasts, a rare lesion mainly associated to impacted and deciduous teeth. It affects mostly young people with an average age of 20 years old, and its preferred location is in the posterior region of the mandible; the lesion will present itself fused both radiologically and microscopically to a root of an erupted permanent tooth, and the anatomopathological diagnosis is obtained through the analysis of the piece sent together with the involved dental element., Case Report: The present study presents a case of cementoblastoma in the mandible involving the second deciduous molar tooth and preventing the eruption of the premolar tooth in a girl aged 11 years old., Discussion: This report discusses relevant aspects concerning clinical, radiographic, and histopathological characteristics and treatments.
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- 2013
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7. Evaluation of the biocompatibility of silicone gel implants - histomorphometric study.
- Author
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França DC, de Castro AL, Soubhia AM, de Aguiar SM, and Goiato MC
- Abstract
Conflict of Interest: NONE DECLARED Breast implants are medical devices that are used to augment breast size or to reconstruct the breast following mastectomy or to correct a congenital abnormality. Breast implants consist of a silicone outer shell and a filler (most commonly silicone gel or saline). Approximately 5 to 10 million women worldwide have breast implants. Histomorphometric study to evaluate the biological tissue compatibility of silicone implants suitable for plastic surgery and the adverse effects and risks of this material. Thirty Wistar white rats received subcutaneous implants and the revestiment of silicone gel Silimed ®®, and randomized into six groups of five animals each, according to the type of implanted material and the time of sacrifice. Eight areas of 60.11mm2 corresponding to the obtained surgical pieces were analyzed, counting mesenchymal cells, eosinophils, and foreign body giant cells, observing an acceptable biocompatibility in all implants, for subsequent statistical analysis by Tukey test. Silicone gel showed inflammation slightly greater than for other groups, with tissue reactions varying from light to moderate, whose result was the formation of a fibrous capsule around the material, recognized by the organism as a foreign body. Despite frequent local complications and adverse outcomes, this research showed that the silicone and top layer presented an acceptable chronic inflammatory reaction, which did not significantly differ from the control group. In general, it is possible to affirm that silicone gel had acceptable levels of biocompatibility, confirmed the rare presence of foreign body giant cells, and when of the rupture, formed a fibrous capsule around the material, separating the material of the organism.
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- 2013
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8. Unusual presentation of oral squamous cell carcinoma in a young woman.
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França DC, Monti LM, de Castro AL, Soubhia AM, Volpato LE, de Aguiar SM, and Goiato MC
- Abstract
Oral squamous cell carcinoma (OSCC) is the most common oral malignant neoplasm, mainly affecting individuals over 50 years old with a history of tobacco and alcohol use. The occurrence of this oral cancer in individuals under 40 years old is unusual and, when it does occur, shows a weaker relation to those risk factors and a more aggressive clinical course. Due to the paucity of reports in this population, it is difficult to prove its increasing trend. A case of oral squamous cell carcinoma in a 39-year-old woman with no history of tobacco or alcohol use is reported. Clinical and histopathological findings, aetiology, and treatment are discussed. The increasing trend of oral squamous cell carcinoma in young women without known risk factors highlights the need for clinicians to be prepared to diagnose this lesion quickly and precisely, providing a better prognosis, chance of survival, and quality of life for the patient.
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- 2012
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9. Maxillary osteosarcoma in a young patient undergoing postorthodontic treatment follow-up: the importance of ongoing oral examinations.
- Author
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Santos-Silva AR, Ribeiro AC, Furuse CF, Simonato LE, Mattar NJ, Soubhia AM, and Miyahara GI
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- Adult, Biopsy, Diagnosis, Differential, Exostoses diagnosis, Female, Follow-Up Studies, Humans, Maxillary Diseases diagnosis, Radiography, Bitewing, Radiography, Panoramic, Tomography, X-Ray Computed, Maxillary Neoplasms diagnosis, Maxillary Sinus Neoplasms diagnosis, Orthodontics, Corrective, Osteosarcoma diagnosis
- Abstract
Osteosarcoma is a common primary malignant tumor in long bones; it generally occurs in young adults. It is considered infrequent in the head and neck regions, where it is usually associated with poor outcomes and rates of survival. From a histopathologic point of view, osteosarcomas are commonly classified as osteoblastic, chondroblastic, or fibroblastic, although several unusual microscopic subtypes have also been reported. The purpose of this article was to present a case report of a maxillary chondroblastic osteosarcoma involving the maxillary sinus and the maxilla of a young woman who was diagnosed during early postorthodontic treatment follow-up. Treatment, prosthetic rehabilitation, and follow-up details are provided. Most importantly, this patient shows the importance of complete and systematic oral examinations during any routine dental treatment., (Copyright © 2011 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.)
- Published
- 2011
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10. High incidences of DNA ploidy abnormalities in tongue squamous cell carcinoma of young patients: an international collaborative study.
- Author
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Santos-Silva AR, Ribeiro AC, Soubhia AM, Miyahara GI, Carlos R, Speight PM, Hunter KD, Torres-Rendon A, Vargas PA, and Lopes MA
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- Adult, Carcinoma, Squamous Cell pathology, Female, Humans, Image Cytometry, International Cooperation, Male, Middle Aged, Neoplasm Staging, Retrospective Studies, Tongue Neoplasms pathology, Aneuploidy, Carcinoma, Squamous Cell genetics, DNA, Neoplasm genetics, Tongue Neoplasms genetics
- Abstract
Aims: This multi-centre analysis assessed the DNA content of TSCC in 37 young patients (<40 years) and 28 old patients (>50 years) and determined the correlation of DNA ploidy findings with clinicopathological data., Methods and Results: Image cytometry was carried out using an automated cellular imaging system on Feulgen-stained histological sections to obtain high-fidelity DNA histograms. Among young patients, 37.8% were females compared to 18.7% in the older group (P=0.002). In total, 48.6% patients were non-smokers and 40.5% were non-drinkers compared to 10.7% non-smokers and non-drinkers in the older group (P<0.0001). TNM, clinical stage of disease and histological grade of differentiation did not differ between groups. Tumour aneuploidy was detected in 86.5% and tetraploidy in 24.3% young patients; this was significantly greater than in the older group where 64.3% were aneuploid (P<0.0001) and 7.2% tetraploid (P<0.0001). The mean values of DNA index (DI) and DNA heterogeneity index as well as the percentage of cells with DI exceeding 5N were higher in young patients (P<0.0001)., Conclusions: Young patients with TSCC represent a distinct clinical entity. The high incidence of DNA ploidy abnormalities suggest that they may have increased genomic instability and indicates underlying genetic differences between TSCC in young and older patients., (© 2011 Blackwell Publishing Limited.)
- Published
- 2011
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11. Biocompatibility evaluation of 3 facial silicone elastomers.
- Author
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França DC, de Castro AL, Soubhia AM, Tucci R, de Aguiar SM, and Goiato MC
- Subjects
- Analysis of Variance, Animals, Connective Tissue pathology, Eosinophils cytology, Giant Cells cytology, Materials Testing, Mesoderm cytology, Rats, Rats, Wistar, Biocompatible Materials chemistry, Maxillofacial Prosthesis, Silicone Elastomers chemistry
- Abstract
The failure of facial prostheses is caused by limitations in the properties of existing materials, especially the biocompatibility. This study aimed to evaluate the biocompatibility of maxillofacial silicones in subcutaneous tissue of rats. Thirty Wistar rats received subcutaneous implants of 3 maxillofacial silicone elastomers (LIM 6050, MDX 4-4210, and industrial Silastic 732 RTV). A histomorphometric evaluation was conducted to analyze the biocompatibility of the implants. Eight areas of 60.11 mm(2) from the surgical pieces were analyzed. Mesenchymal cells, eosinophils, and foreign-body giant cells were counted. Data were submitted to analysis of variance and Tukey test. Initially, all implanted materials exhibited an acceptable tissue inflammatory response, with tissue reactions varying from light to moderate. Afterward, a fibrous capsule around the silicone was observed. The silicones used in the current study presented biocompatibility and can be used for implantation in both medical and dental areas. Their prosthetic indication is conditioned to their physical properties. Solid silicone is easier to adapt and does not suffer apparent modifications inside the tissues.
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- 2011
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12. Mucocele of the glands of Blandin-Nuhn--clinical, pathological, and therapeutical aspects.
- Author
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Adachi P, Soubhia AM, Horikawa FK, and Shinohara EH
- Subjects
- Diagnosis, Differential, Humans, Mucocele diagnosis, Mucocele surgery, Salivary Gland Diseases diagnosis, Salivary Gland Diseases surgery, Salivary Glands, Minor surgery, Tongue Diseases diagnosis, Tongue Diseases surgery, Mucocele pathology, Salivary Gland Diseases pathology, Salivary Glands, Minor pathology, Tongue Diseases pathology
- Abstract
Purpose: This study aims to review anatomical, clinical, and pathological concepts as well as to discuss the most adequate therapeutic approach to the mucoceles of the glands of Blandin-Nuhn., Discussion: The glands of Blandin-Nuhn are localized in the ventral part of the tongue, next to the apex in the lingual median plane. Development of a mucocele in this site is rarely seen; besides, as the glands of Blandin-Nuhn are not encapsulated and are directly overlapped to the muscle tissues, their manipulation tends to be different from the other oral mucoceles., Conclusion: As Blandin-Nuhn mucoceles are uncommon and their clinical appearance could be similar to other lesions, it is important that health professionals know their clinical and histopathological features to avoid having them misdiagnosed.
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- 2011
- Full Text
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13. Atypical dento-alveolar fracture fixed with screws: a technical note.
- Author
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Shinohara EH, Vieira EH, Júnior IR, Pires-Soubhia AM, and Martini MZ
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- Adult, Facial Injuries surgery, Fracture Fixation, Internal methods, Fractures, Comminuted surgery, Humans, Male, Mouth injuries, Soft Tissue Injuries surgery, Alveolar Process injuries, Bone Screws, Fracture Fixation, Internal instrumentation, Mandibular Fractures surgery, Maxillary Fractures surgery, Tooth Fractures surgery, Wounds, Gunshot surgery
- Abstract
Dento-alveolar process fracture is an important and common event in the dental office practice usually managed under the well-established protocols, but sometimes this kind of lesion is evaluated in the hospital emergency rooms without attention to the dental injuries. In this type of trauma, the time between the injury and the definitive resolution is essential for the treatment success, usually 1 h in cases of dento-alveolar fractures (tooth and alveolar bone). This paper describes the management of a patient with unusual dento-alveolar fracture caused by gunshot and treated using screw fixation.
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- 2010
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14. Formalin burn.
- Author
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Ribeiro AC, Simonato LE, Santos-Silva AR, de Moraes NP, and Soubhia AM
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- Humans, Lip injuries, Male, Middle Aged, Mouth Mucosa injuries, Self Care adverse effects, Stomatitis, Aphthous drug therapy, Burns, Chemical etiology, Disinfectants adverse effects, Formaldehyde adverse effects, Oral Ulcer chemically induced
- Published
- 2010
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15. Osteolipoma of the buccal mucosa.
- Author
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de Castro AL, de Castro EV, Felipini RC, Ribeiro AC, and Soubhia AM
- Subjects
- Female, Humans, Middle Aged, Lipoma pathology, Mouth Mucosa, Mouth Neoplasms pathology
- Abstract
Lipomas are benign mesenchymal neoplasms of soft tissue that can be found in any part of the human body. Conversely, their presence in the oral mucosa is rather uncommon, with approximately 4% of the cases occurring in the oral cavity. In such cases, they are likely to have originated from mature adipose tissue and to be among several described histological variants of lipomas, which are identified according to the predominant type of tissue. There is a rare lipoma, known as an osteolipoma or an ossifying lipoma; however, little has been written this type of lipoma characterized by a classical lipoma with areas of osseous metaplasia. Considering the few cases of oral osteolipomas previously described in the English-related literature and the consequent risk of misdiagnosis and overtreatment, this paper describes an extreme case of an osteolipoma affecting the buccal mucosa of an adult patient. This paper focuses particularly on the pathogenesis of this lesion and the discussion of a correct diagnosis.
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- 2010
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16. Immunoexpression of keratins in the calcifying cystic odontogenic tumor epithelium.
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Crivelini MM, Felipini RC, Coclete GA, and Soubhia AM
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- Cell Differentiation, Cell Transformation, Neoplastic, Collagen Type IV biosynthesis, Epithelium metabolism, Humans, Immunohistochemistry, Laminin biosynthesis, Vimentin biosynthesis, Jaw Neoplasms metabolism, Jaw Neoplasms pathology, Keratins biosynthesis, Odontogenic Cyst, Calcifying metabolism, Odontogenic Cyst, Calcifying pathology
- Abstract
Ameloblastomatous epithelium containing clusters of ghost cells is the typical histopathology of calcifying cystic odontogenic tumor (CCOT). This paper aimed to assess keratins AE1-AE3, K7, K10/13, K14, K18, K19, vimentin, laminin, and collagen IV in 08 CCOTs to discuss their histopathogenesis. Similarity to the immunoprofile of the stratified squamous epithelium was seen in the with the basal layer expressing K14 and the upper cells expressing K10/13. When compared to the immunoprofile of the normal odontogenic epithelium, of odontogenic tumor epithelia and of the ghost cells described in the literature, it was possible to suggest that the CCOT epithelium differentiates towards squamous type.
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- 2009
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17. Clinical and histopathological analysis of oral squamous cell carcinoma in young people: a descriptive study in Brazilians.
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Ribeiro AC, Silva AR, Simonato LE, Salzedas LM, Sundefeld ML, and Soubhia AM
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- Adult, Age Factors, Brazil, Female, Humans, Male, Middle Aged, Neoplasm Staging, Retrospective Studies, Carcinoma, Squamous Cell pathology, Mouth Neoplasms pathology
- Abstract
We retrospectively analysed the clinical and histological characteristics of oral squamous cell carcinoma (SCC) in a sample of Brazilian patients 45 years of age or less. Files from a single oral histopathological service were studied during the period 1990 to 2005 and the clinical data collected. The histological sections of the invasive part of each tumour were analysed and classified using the criteria of Bryne et al. A total of 46 patients were selected, 36 (78%) of whom were white; 38 (83%) were male; and the most common site was the floor of the mouth (n=14, 30%) followed by the tongue (n=13, 28%). Most selected patients used tobacco and alcohol, and 43 were diagnosed as having clinical stages III and IV disease. Nine of the tumours (20%) were well differentiated, 23 were moderately differentiated, and the rest (n=14) were poorly differentiated. The characteristics of this group suggest that oral SCC in young patients does not behave differently from the oral SCC found in the overall population.
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- 2009
- Full Text
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18. Presence of bacteria in dentinal tubules.
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Kina JR, Kina J, Kina EF, Kina M, and Soubhia AM
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- Bacteria, Anaerobic isolation & purification, Humans, Male, Middle Aged, Dentin microbiology, Periodontal Pocket microbiology, Tooth Root microbiology
- Abstract
This study demonstrated that a significant number of bacteria is present in the radicular dentinal tubules of periodontally diseased human teeth. Ten periodontally diseased teeth were prepared and stained by Brown and Brenn technique for histological examination. Bacteria were detected in all teeth. It is suggested that bacteria may invade dentinal tubules exposed to periodontal pocket and are very hard to be eliminated by conventional mechanical and chemical periodontal therapy. Contaminated dentinal tubules of periodontally diseased teeth can thus act as active bacterial reservoirs to promote recolonization of mechanically treated root surfaces, which could interfere with the periodontal healing and progression of the disease.
- Published
- 2008
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19. Peripheral cemento-ossifying fibroma in child. A follow-up of 4 years. Report of a case.
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Delbem AC, Cunha RF, Silva JZ, and Soubhia AM
- Abstract
Peripheral cement-ossifying fibroma is a relatively common gingival growth of a reactive rather than neoplastic nature, whose pathogenesis is uncertain. It predominantly affects adolescents and young adults, with peak prevalence between 10 and 19 years. We report here the clinical case of a 5-year-old girl with disease duration of 3 years, who was followed up for 4 years, showing a gingival health and normal radiopacity of bone.
- Published
- 2008
20. Unusual wooden foreign body in the palate.
- Author
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Soubhia AM, Ribeiro AC, Martins LD, Silva AR, and Lopes MA
- Subjects
- Diagnosis, Differential, Foreign Bodies diagnosis, Humans, Male, Microscopy, Electron, Scanning, Middle Aged, Odontogenic Tumors diagnosis, Palatal Neoplasms diagnosis, Wood, Dental Devices, Home Care adverse effects, Foreign Bodies etiology, Palate, Hard
- Abstract
We report a case of a palatal calcified foreign body simulating an odontogenic lesion. Surgical exploration revealed a calcified mass that was analysed under light microscopy and identified as a vegetal foreign body. Further scanning electron microscopy analysis revealed that the foreign body was a piece of wood. Hard palate foreign bodies have been reported previously, however, it seems that this is the first case of its kind.
- Published
- 2007
- Full Text
- View/download PDF
21. Oral cysticercosis: case report.
- Author
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Ribeiro AC, Luvizotto MC, Soubhia AM, and de Castro AL
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- Adolescent, Animals, Diagnosis, Differential, Female, Humans, Larva, Mouth Mucosa pathology, Cysticercosis pathology, Mouth Diseases pathology
- Abstract
Frequent in developing countries, cysticercosis is a parasitic infection that rarely involves the mouth. This study reports a case of oral cysticercosis in a 13-year-old female patient who had an asymptomatic nodule in the right labial mucosa. An excisional biopsy was carried out and the histopathologic examination revealed a cystic space containing a Taenia solium larva.
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- 2007
- Full Text
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22. Paradental cyst: report of two cases.
- Author
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Kanno CM, Gulinelli JL, Nagata MJ, Soubhia AM, and Crivelini MM
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- Adult, Diagnosis, Differential, Humans, Male, Mandibular Diseases diagnostic imaging, Molar, Third physiopathology, Periodontal Cyst diagnostic imaging, Radiography, Tooth Eruption, Mandibular Diseases pathology, Periodontal Cyst pathology
- Abstract
Background: The paradental cyst is an odontogenic lesion of inflammatory origin that has few clinical signs and symptoms apart from recurring acute episodes. A well-defined radiolucency associated with the roots or distal to the crown may be seen radiographically. The purpose of this article is to report on different aspects of two cases involving paradental cysts. In the first case, the patient complained about recurring pericoronitis. A semilunar-shaped radiolucency on the distal aspect of the mandibular third molar was noted on the periapical radiograph. In the second case, the patient's main complaint was chronic trauma of the overlying mucosa. Radiographs revealed an enlarged pericoronal space., Methods: In both cases, the mandibular third molar was extracted due to a lack of space. Lesional samples were sent for histopathologic analysis., Results: In the first case, the drainage of cystic fluid and a regular concavity were found during tooth removal. In the second case, a nodular lesion was found adhering to the disto-buccal surface of the tooth arising from the distal wall of a periodontal pocket. The histopathologic analysis revealed a hyperplastic stratified squamous epithelium with arcading lining a fibrous capsule with inflammatory infiltrate, resulting in a final diagnosis of a paradental cyst., Conclusions: The presence of a paradental cyst should be considered when recurrent inflammatory periodontal processes are associated with partially erupted vital teeth, even when characteristic radiographic findings are absent. Definitive diagnosis requires a clinicopathologic correlation incorporating surgical, radiographic, and histologic findings.
- Published
- 2006
- Full Text
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23. Study on the origin and nature of the adenomatoid odontogenic tumor by immunohistochemistry.
- Author
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Crivelini MM, Soubhia AM, and Felipini RC
- Abstract
The adenomatoid odontogenic tumor (AOT) is a clinically benign lesion. Discussions about the AOT hamartomatous or neoplastic nature, and the probable odontogenic epithelial cell it originates from still exist. This research aimed to study and discuss the subject by the immunohistochemical detection of cytokeratins, laminin, collagen IV, PCNA and p53 in 8 tumor samples and 8 dental follicle samples containing reduced enamel epithelium. The results have shown that CK14 labelling indicated differentiation grades for secreting ameloblasts or ameloblasts in the post-secreting stage in the adenomatoid structure of AOT. Laminin, found on the luminal surface of adenomatoid structures, was compatible with the reduced enamel epithelium during the "protective stage of amelogenesis". PCNA specifically labelled the spindled areas and peripheral cords of the AOT, indicating that these areas are responsible for tumor growth. After considerations about pathogenesis, the authors suggested that the nature of AOT is hamartomatous with histogenesis from the reduced enamel epithelium.
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- 2005
- Full Text
- View/download PDF
24. Immunohistochemical aspects of basal cell adenoma and canalicular adenoma of salivary glands.
- Author
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Machado de Sousa SO, Soares de Araújo N, Corrêa L, Pires Soubhia AM, and Cavalcanti de Araújo V
- Subjects
- Actins metabolism, Adenocarcinoma pathology, Adenoma pathology, Humans, Immunohistochemistry, Keratin-7, Keratins metabolism, Salivary Gland Neoplasms pathology, Vimentin metabolism, Adenocarcinoma metabolism, Adenoma metabolism, Neoplasm Proteins metabolism, Salivary Gland Neoplasms metabolism
- Abstract
Basal cell adenoma is a benign epithelial neoplasm with a uniform histologic appearance dominated by basaloid cells. Those cells may be distributed in various arrangements as solid, trabecular, tubular and membranous. Canalicular adenoma is also a benign neoplasm composed by columnar cells arranged in branching and interconnecting cords of single or double cell thick rows. There is some disagreement among investigators about whether canalicular adenoma should be included within the basal cell adenoma histologic spectrum. In the present study we compared the expression of cytokeratins (CK), vimentin and muscle-specific actin, utilizing immunohistochemical technique, in three cases diagnosed as basal cell adenomas predominantly of the solid type, and three cases of canalicular adenomas. The results obtained showed a distinct immunoprofile for both neoplasms. Solid areas of basal cell adenomas did not stain for any of the tested antibodies; only when there was tubular differentiation, those structures expressed CKs 7, 8, 14, and 19 in luminal cells and vimentin in non-luminal cells. On the other hand, canalicular adenomas strongly expressed CKs 7 and 13. The panel of antibodies utilized supports the separation of the two entities.
- Published
- 2001
- Full Text
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25. Heterotopic gastrointestinal cyst partially lined with dermoid cyst epithelium.
- Author
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Crivelini MM, Soubhia AM, Biazolla ER, and Neto SC
- Subjects
- Adolescent, Endoderm pathology, Epithelium pathology, Goblet Cells pathology, Hair Follicle pathology, Humans, Male, Sebaceous Glands pathology, Choristoma pathology, Dermoid Cyst pathology, Gastric Mucosa pathology, Intestinal Mucosa pathology, Mouth Diseases pathology, Mouth Floor pathology, Mouth Neoplasms pathology
- Abstract
We report a rare heterotopic gastrointestinal cyst located in the right submandibular/submental area with histopathologic features that included portions resembling a dermoid cyst. Some theories of pathogenesis are discussed, and an origin of this lesion in entrapped undifferentiated endodermal cells is suggested.
- Published
- 2001
- Full Text
- View/download PDF
26. [Alveolar socket repair in rats treated with sugar cane brandy. Histological study].
- Author
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Pires Soubhia AM and Martinelli C
- Subjects
- Alcoholism, Animals, Rats, Rats, Inbred Strains, Tooth Extraction, Alveolar Process drug effects, Ethanol adverse effects, Wound Healing drug effects
- Published
- 1987
27. [The effect of progestagen medroxyprogesterone acetate on the healing of dental extraction wounds. Histological study in rats].
- Author
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Nogueira Campos CR, Mateus G, and Pires Soubhia AM
- Subjects
- Animals, Female, Rats, Time Factors, Medroxyprogesterone therapeutic use, Tooth Extraction, Wound Healing drug effects
- Published
- 1986
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