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1. TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2.

Author

Pasparakis, Manolis, Courtois, Gilles, Hafner, Martin, Smidt-Supprian, Marc, Nenci, Arianna, Toksoy, Atiye, Krampert, Monica, Goebeler, Matthias, Gillitzer, Reinhard, Israel, Alain, Krieg, Thomas, Rajewsky, Klaus, and Haase, Ingo

Subjects
KERATINOCYTES, MICE, CYTOLOGY, PHYSIOLOGY
Abstract

Presents a study that investigated the function of I κ B kinase 2 (IKK2) specifically in epidermal keratinocytes using Cre/loxP-mediated gene targeting. Effect of IKK2 deficiency; Effect of epidermis-specific deletion of IKK2 on mice; Function of IKK2-mediated NF- κ B activity in epidermal keratinocytes.

Published
2002
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