787 results on '"Schulman, Brenda A"'
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2. Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation
3. Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE
4. Combinatorial selective ER-phagy remodels the ER during neurogenesis
5. Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases
6. Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5
7. Activity-based profiling of cullin–RING E3 networks by conformation-specific probes
8. mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway
9. Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism
10. Insights into the ISG15 transfer cascade by the UBE1L activating enzyme
11. Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
12. APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain
13. Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies
14. An expanded lexicon for the ubiquitin code
15. K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution
16. Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.
17. E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity
18. Structure of CRL7FBXW8 reveals coupling with CUL1–RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation
19. ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection
20. Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation
21. DIA-based systems biology approach unveils E3 ubiquitin ligase-dependent responses to a metabolic shift
22. Noncanonical assembly, neddylation and chimeric cullin–RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex
23. Lysosomal storage disease proteo/lipidomic profiling using nMOST links ferritinophagy with mitochondrial iron deficiencies in cells lacking NPC2
24. CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation
25. Decoding the messaging of the ubiquitin system using chemical and protein probes
26. FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesis
27. Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE
28. Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler
29. Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly
30. Skraban‐Deardorff intellectual disability syndrome‐associated mutations in WDR26 impair CTLH E3 complex assembly.
31. Recovering from the stress of the COVID-19 pandemic
32. Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
33. Catalysis of non-canonical protein ubiquitylation by the ARIH1 ubiquitin ligase
34. Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site
35. Data-independent acquisition method for ubiquitinome analysis reveals regulation of circadian biology
36. Paradoxical mitotic exit induced by a small molecule inhibitor of APC/CCdc20
37. Structural and functional characterization of GID/CTLH E3 ubiquitin ligases
38. Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis
39. Atomistic Autophagy: The Structures of Cellular Self-Digestion
40. To be (in a transcriptional complex) or not to be (promoting UBR5 ubiquitylation): That is an answer to how degradation controls gene expression
41. E3-mediated Ubiquitin and Ubiquitin-like Protein Ligation: Mechanisms and Chemical Probes
42. Host ubiquitin protein tags lipid to fight bacteria
43. The UbcH8 Ubiquitin E2 Enzyme Is also the E2 Enzyme for ISG15, an IFN-α/β-Induced Ubiquitin-Like Protein
44. A Pro‐Fluorescent Ubiquitin‐Based Probe to Monitor Cysteine‐Based E3 Ligase Activity
45. Combinatorial selective ER-phagy remodels the ER during neurogenesis
46. PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems
47. Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum
48. Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
49. Quantifying the heterogeneity of macromolecular machines by mass photometry
50. Role of the F-box Protein Skp2 in Lymphomagenesis
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