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1. AVALIAÇÃO ECOCARDIOGRÁFICA DA VÁLVULA MITRAL

Author

BARBOSA JÚNIOR, MAURÍCIO MENEZES, primary, SILVA JÚNIOR, LUÍZ TEIXEIRA DA, additional, CECCON, ROBSON, additional, TEIXEIRA, LIDIA FARIA, additional, ROCHA, ISADORA GUIMARAES DA, additional, OLIVEIRA, MATHEUS YAN SOBRAL TEIXEIRA, additional, TOMÉ, SILVANA OLIVEIRA, additional, SANTOS, RENATO CASTILHO DOS, additional, BRANDÃO, GISELE GOMES, additional, DUTRA, RAPHAELA NOGUEIRA, additional, MILANI, CAETANO PASCHOAL VIEIRA, additional, ARFOX, MUNIR IBEN, additional, MELO, YASMIN SÁ DE, additional, AYETA, CAROLINE DIB DE OLIVEIRA, additional, and PROENÇA, PÂMELA GARCIA SCHONFELDER DE, additional

Published
2022
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2. REVASCULARIZAÇÃO MIOCÁRDICA NO CONTEXTO DA DOENÇA ARTERIAL CORONARIANA ESTÁVEL

Author

GERONIMO, RENAN MIGUEL PORCINI, primary, BARBOSA JÚNIOR, MAURICIO MENEZES, additional, SILVA JÚNIOR, LUÍZ TEIXEIRA DA, additional, CECCON, ROBSON, additional, OLIVEIRA, MATHEUS YAN SOBRAL TEIXEIRA, additional, SANTOS, RENATO CASTILHO DOS, additional, TOMÉ, SILVANA OLIVEIRA, additional, BRANDÃO, GISELE GOMES, additional, DUTRA, RAPHAELA NOGUEIRA, additional, RAMOS, GEOVAM NATAL LIMA, additional, MACHADO, ANA KAROLINE DE ALMEIDA, additional, TRINKEL, GUSTAVO BECKERT, additional, PROENÇA, PAMELA GARCIA SCHONFELDER DE, additional, GADBEN, CHRISTIAN FERREIRA, additional, and TEIXEIRA, LIDIA FARIA, additional

Published
2022
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3. HEMORRAGIA PÓS-PARTO E O SEU MANEJO MÉDICO, MINIMAMENTE INVASIVO E POR LAPAROTOMIA

Author

PIZZOL, MATHEUS HENRIQUE, primary, BATTISTELLA JUNIOR, MARIO JOSÉ, additional, SILVA JÚNIOR, LUÍZ TEIXEIRA DA, additional, DUARTE, LARISSA PEREIRA, additional, AMARAL, FERNANDO HENRIQUE FARIA DO, additional, OLIVEIRA, HAYANE SOUZA DE, additional, RAMOS, GEOVAM NATAL LIMA, additional, MACHADO, ANA KAROLINE DE ALMEIDA, additional, BENTES, BARBARAH ALBUQUERQUE, additional, MACACARI, BEATRIZ, additional, MELO, SIDNEY JUNIOR VIEGAS DE, additional, DIAS, BÁRBARA INCERTE, additional, SILVA, ANA MARIA DA, additional, and PROENÇA, PÂMELA GARCIA SCHONFELDER DE, additional

Published
2022
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4. Trauma e Emergência - Teoria e Prática

Author

SOUZA, ANNA JÚLIA ARRAES ALVES DE, primary, GALDINO, NAYARA DA SILVA, additional, Barros, Kátia Talita dos Santos, additional, Santos, Rafaela Martins, additional, Gomes, Rafaella Storck, additional, Araújo, Rodolfo Lima, additional, Apolinário, Matheus Felipe, additional, Quitete, Matheus Augusto Coelho, additional, GORINO, ALESSANDRA SOICA, additional, Azevedo, Luisa Tavares de, additional, Melo, Mariana Ramos Peixoto, additional, Mesquita, Sarah Franco Nogueira, additional, Apolinário, Pedro Lucas, additional, Apolinário, João Pedro Costa, additional, Silva, João Felipe Tinto, additional, Costa, Jaqueline Brito Da, additional, Costa, Iracema Silva Da, additional, Barboza, Laine Da Costa Almeida, additional, Santos, Raiane Lira Dos, additional, Almeida, Valéria Fernanda Da Silva, additional, Martins, Alaine Dos Santos Silva, additional, Homem, Dayla Soeiro, additional, Silva, Aline Alves da, additional, Máximo, Klecia Nogueira, additional, Brito, Shirley De Vasconcelos Bonfim, additional, Melo, Viviane Dos Santos, additional, Sobrinho, Celice Ruanda Oliveira, additional, MORAIS, LYNNA STEFANY FURTADO, additional, Rodrigues, Thays Pereira, additional, Cruz, Taize Vieira Da, additional, Moreira, Luiz Felipe Guimarães Gualberto, additional, Queiroga, Lucas dos Santos, additional, Figueira, Luís Eduardo Oliveira, additional, Ramalho, Lívia Corrêa, additional, Nepomuceno, Lara Reggiani, additional, Pena, Lavínia Vasconcellos Patrus, additional, Nardelli, Lucas Jorge, additional, Abreu, João Victor Silva, additional, Pereira, Carolina Monte Santo Burdman, additional, Reis, Idahil Pereira dos, additional, Borges, Guilherme Dantas, additional, Vieira, Ana Izabel Aparecida, additional, Barros, Laura Marques, additional, Ferreira, Regina Lígia Gomes, additional, Dias, Débora Francielle, additional, Vieira, Eliano Atanázio, additional, Luz, Pedro Miguel Calife da, additional, Lopes, Bruno Augusto, additional, Silva, Mariana Pereira Barbosa, additional, Moura, Layanne Cavalcante de, additional, Luz, Thiago Evencio Mendes, additional, Oliveira, Caio Matheus Feitosa de, additional, Cavalcanti, André Luis Mendes, additional, Sobrinho, Salomão Xavier, additional, Brayner, Luís Eduardo Arcoverde Nogueira, additional, Resende, Wanderley Lopes, additional, Nogueira, Maria Eduarda Martins, additional, Maciel, Amanda Costa, additional, Lima, Lívia Gonçalves de, additional, Barreto, Jadson Viana, additional, Apolinário, Joelma Maria dos Santos da Silva, additional, nunes, Cleiciane remigio, additional, Ribeiro, Yonara Cristiane, additional, Francischetto, Camilla Tozi, additional, Santos, Camila Duarte Lage dos, additional, Silva, Danielle Lopes da, additional, Said, Camila do Carmo, additional, Rolim, Marcella Dovera Soares, additional, Lopes, Luiza Silva, additional, Cunha, Julia Felix Raposo Martins da, additional, Simões, Barbara dos santos, additional, Gomes, Monique Benemérita Vilela, additional, Fernandez, Miguel Godeiro, additional, Vilela, Monica Suzana Alves, additional, Aragão, José Aderval, additional, Albuquerque, Aglaé Travassos, additional, Brito, Victória Rezende De, additional, Aragão, Felipe Matheus SantAnna, additional, Aragão, Iapunira Catarina SantAnna, additional, Reis, Francisco Prado, additional, Koupak, Fabiana, additional, LENTSKC, MAICON HENRIQUE, additional, Casagrande, Duane, additional, Trincaus, Maria Regiane, additional, Souza, Pollyanna Bahls de, additional, BARATIERI, TATIANE, additional, Soares, Leticia Gramazio, additional, Pinheiro, Raul Henrique de Oliveira, additional, Pelazza, Bruno Bordin, additional, PITILIN, ERICA DE BRITO, additional, Prezotto, Kelly Holanda, additional, Silva, Marcos Maciel da, additional, Paris, Matheus da Cunha, additional, Paiva, Paula Costa Vieira, additional, Carvalho, Tiago Silva e, additional, Silva, Giorgia Janaína S. Pires da, additional, Rocha, André Versiani Caldeira, additional, Siqueira, Camila Bruck de, additional, Souza, Marta Bhering Pereira de, additional, Carvalho, Victoria Caroline Silva, additional, Moreira, Saulo Guimarães, additional, Caldas, Vitor Hugo Rocha, additional, Coimbra, Yasmin Sotero, additional, Queiroz, Isabella Cardoso, additional, Maia, Isadora rosa, additional, Barros, João Victor Teodoro Pires de, additional, Martins, Karine Felipe, additional, Vallim, Yuri Vasconcellos, additional, Garcia, Beatriz Rosa, additional, Guedes, Branca Lopes da Silva, additional, Fraga, Daniele da Rosa, additional, Rusch, Gabriela de Souza, additional, Faustino, Gabriella Picoli dos Santos, additional, Portela, Marcus Vinicius Menezes, additional, Lins, Maria Heloisa de Albuquerque Calenzo, additional, Quadros, Maria Luísa Rabelo, additional, Veloso, Maria Luíza da Silva, additional, Aguiar, Marina Cavalcante Rodrigues de, additional, Miaki, Roberto Oliveira, additional, Silva, Serginara Cristina Flexa Pereira da, additional, Castro, Yara Fernandes Ribeiro de, additional, REIS, Bruno Cezario Costa, additional, Sobrinho, Weberton Dorásio, additional, Rover, Luciana Fernandes, additional, Carvalho, David Emanuel Lima de, additional, Vieira, Camila Medeiros, additional, Postigo, Isabella Stéfanny de Freitas, additional, Lima, Natália Martins de, additional, Ferreira, Poliana Silva, additional, Zacarias, Juliana Reis de Sousa, additional, Kato, Ana Beatriz Doufem, additional, Souto, Karoline de Oliveira Lins, additional, Oliveira, Carla Resende Vaz, additional, Lacerda, Felipe Junksztejn, additional, Cordeiro, Gabriela Lima, additional, Leite, Sarah de Maciel, additional, Ferreira, Wesley Cristian, additional, Camargo, Monique, additional, Vieira, Raquel dos Santos, additional, Zusman, Gabriela Lachter, additional, Silva, Amanda Rocha Fernandes da, additional, Lima, Jessica Abdala, additional, Bastos, Beatriz Souza, additional, Nunes, Maria Eduarda Fernandes, additional, Reis, Bruno Cezario Costa, additional, Souza, Milena Rafaela Pinto Moraes de, additional, Ramos, Yalle Moraes Souza, additional, Lima, Laura Rasul de, additional, Jacob, Isabela Matos Augosto, additional, Costa, Gabrieli Casara Carvalho da, additional, Pedrotti, Mateus Vinicius, additional, Scopel, João Victor Magalhães, additional, Faria, Regina Bicalho Gomes de, additional, Graciano, Guilherme Fonseca, additional, Jordão, Igor Marques, additional, Santos, Ítalo Henrique dos, additional, Ribeiro, João Victor Silva, additional, Ribeiro, Leonardo Barbosa, additional, Gonçalves, Mônica Aramuni, additional, Freitas, Pedro Humberto Gomes de, additional, Rodrigues, Thais de Oliveira, additional, Oliveira, Vanuza Regina Lommez de, additional, Silva, Victor Hugo Martins Paula da, additional, Silva, Yuri Martins, additional, Pena, Natália Fenner, additional, Lauria, Márcio Weissheimer, additional, Schwamback, Gabriel Irismar Rodrigues, additional, Rodrigues, Brenda dos Santos, additional, Ivankovics, Beatriz Maria Graça, additional, Canto, Camilla Geny Leseux, additional, Luna, Daniele de Oliveira, additional, Carneiro, Gabriela Vargas, additional, Pinto, Guilherme Gomes, additional, Sousa, Jamila Xavier de, additional, Mosconi, Lucca Dias, additional, Guimarães, Bernardo Jardim, additional, Valverde, Jessica Ariane Silva, additional, Ponce, Maria Luisa Pedigoni, additional, Mariconi, Rafael Tessari, additional, Mattar, Sofia Borini Avelar, additional, Silva, Wilson Santana, additional, Isaac, Álvaro Martins Gabriel, additional, Cavalieri, Marilene Ferraz, additional, Pereira, Gabriel Braga, additional, Soares, Bruno Vieira, additional, Cabral, Larissa de Menezes, additional, Vieira, Suellen Duarte, additional, Bermal, Matheus Ribeiro, additional, Leite, João Luiz Chaves Ferreira, additional, Eibel, Alcides Eduardo, additional, Milani, Caetano Paschoal Vieira, additional, Vieira, Joselita Brito de Oliveira, additional, Pelegrini, Raimundo José, additional, Gomes, Eliphas Levi Assumpção Egg, additional, Proença, Pâmela Garcia Schonfelder de, additional, SILVA, WILSON SANTANA, additional, Souza, Lidia Carneiro de, additional, Carvalho, Vívian Moreira de, additional, Cunha, Lucas Miranda da, additional, carvalho, Lílian Moreira de, additional, Carvalho, Gabriel Andrade Bonanno, additional, Paiva, Ana Clara Ribeiro Araújo, additional, Mineiro, Pedro Henrique Martins, additional, Amaral, Túlio Bittencourt, additional, Gasperini, Arthur Mendes, additional, Oliveira, Mariana Almeida de, additional, Benício, Carlos Artur, additional, Buzollo, Gabriela Ferreira, additional, Fernandes, Thiago Barbosa, additional, Fernandes, Ana Flávia Barbosa, additional, Castro, Thais Carolina Fernandes de, additional, Pereira, Victoria de Paula, additional, Aredes, Pedro Arthur Moreira, additional, Ribeiro, Ana Luísa Nunes, additional, Toledo, Vanessa Herculano, additional, Marques, Ana Beatriz Barreto, additional, Barrilao, Lorena de Pinho, additional, Marciano, Ingrid Grazielle da Silva, additional, Oliveira, Kennedy Martinez de, additional, Costa, Caio Pluvier Duarte, additional, Barbosa, Bernardo Brandão, additional, Braga, Samuel Vitorio, additional, Mello, Thiago Souza de, additional, Macedo, Alice Freitas, additional, Mugayar, Amanda Amorim, additional, Massahud, Felipe Corrêa, additional, Ribeiro, Ana Sofia Sousa, additional, Nunes, Carol Baby, additional, Maximiano, Marianna Letícia de B., additional, Oliveira, Beatriz Carvalho de, additional, Souza, Ana Carolina Azevedo, additional, Luvizotto, Pedro Henrique de M., additional, Lima, Giovanna Aparecida Balarini, additional, Prevedello, Alexandra Secreti, additional, Oliveira, Bárbara Martins Mello de, additional, Mileti, Daniela Rambaldi, additional, Oliveira, Dara Campos de, additional, Silva, Geisa Maria Lourenço, additional, Vitti, Isabela Fialho, additional, Oliveira, Pedro Martins, additional, Dias, Rafaela Gonçalves, additional, Souza, Rayssa Victória Couto e, additional, Freitas, Giuliana Leandro de Sousa, additional, Oliveira, Artur Alexandre de, additional, Alves, Nathanael dos Santos, additional, Oliveira, Camila Araújo, additional, Veras, Marcos Antônio Moraes, additional, Souza, Isabelle Brito, additional, Cunha, Abrahão Lincoln Alves, additional, Silva, Raí Emanuel da, additional, Jesus, Felipe Emannuel Alvino de, additional, Santos, Ingredy Lopes dos, additional, Pinheiro, Breno Gonçalves, additional, Sousa, Jhoana Darc Lopes de, additional, Sousa, Vanessa G De, additional, Souza, Jéssica Maria Teles, additional, Barros, Ayslan Batista, additional, Gomes, Thiago Nobre, additional, Silva, Pedro Henrique Fonseca da, additional, Lenhardt, Debora Giachini, additional, Romão, Gabriel Moreira, additional, Braun, Beatriz Olenski, additional, Uehara, Gabriela Mayumi, additional, Silva, Pablo Oliveira da, additional, Yamada, Isabela Yurie, additional, Tanaka, Henrique Toshio Fujizawa, additional, Melo, Mateus Scaliante, additional, Geminiano, Heloísa, additional, Gonçalves, Júlia Assis, additional, Mattos, Raphael Nardelli De, additional, Morais, Ricardo Silva Gastão, additional, Gonçalves, Rodrigo Tavares, additional, Paiva, Adolfo Edson Souza, additional, SANTOS, AMANDA SIMÕES, additional, Corato, Ana Carolina Luquezi, additional, Carvalho, Elisa Moraes, additional, Diniz, Emanuel Tiso de Araújo, additional, Pereira, Helena Costa, additional, Oliveira, Isadora Fernandes Dias de, additional, Aquino, Leonardo Júnior Matheus de, additional, Mangini, Luiza Ferraz, additional, Vilela, Maria Luiza Cobra, additional, Figueiredo, Otho Melo de, additional, Reis, Renan Israel, additional, Mousinho, Ayana Rocha Pôrto, additional, Gomes, Pedro Vinícius Teles, additional, Batista, Matheus Neres, additional, Oliveira, Edson Ferreira de, additional, Silva, Osmar Nascimento, additional, Pinheiro, Elisama Pereira, additional, Sousa, Joel Alves de, additional, Vieira, Ana Júlia, additional, SANTOS, JEHOVAHNNA ANTTONIONI, additional, Spósito, Lavínia Arruda, additional, Puglia, Ana Clara, additional, Moral, Lorena Ramos, additional, Moreira, Anna Luiza Gonçalves, additional, Abreu, Gabriel Sousa de Freitas, additional, Rios, Marcella Maciel, additional, Costa, Anna Laura Caetano, additional, Freitas, Valdemiro, additional, oliveira, Andressa Fernanda Dos Santos Melo, additional, Alencar, Ana Clara Silva de, additional, Santos, João Gabriel Duarte, additional, Sá, Emanuely Gomes de Pádua, additional, Costa, Ana Carla Cardoso, additional, Muniz, Sandara Cardoso, additional, Simão, Sahda Elouf, additional, Oliveira, Kauanna Layla Marques Cavalcanti de, additional, Mendes, Cibele Corrêa, additional, Duarte, João Victor Carvalho, additional, Araújo, Maria Isabella Farias de, additional, Gerreira, Gloria Maria Grangeiro, additional, Silva, Lays Samara da Costa Silva e, additional, Guimarães, Dailyt Salvador, additional, Garcia, Fabiane Weber, additional, Kantoviscki, Andréia Lara Lopatko, additional, Lustosa, Julia Deolinda, additional, Santos, Sheila Ferreira dos, additional, Lisboa, Maria Gabriela, additional, Ribeiro, Flávia Coutinho Loureiro, additional, Peixoto, Maria Clara Almeida, additional, Santos, Arthur Barbosa, additional, Couto, Fernanda Machado, additional, Reis, Alexia Cristina Soares Dos, additional, SILVA, Rita de Cássia, additional, Souza, Rafael Cota Andrade Ferreira De, additional, Domiciano, Leticia Santana, additional, Godinho, Camila, additional, Alves, Laura Portela, additional, Santos, Letícia de Oliveira, additional, Santos, Letícia Diniz, additional, Magalhães, Luisa de Aguiar, additional, Murta, Luisa de Sousa Mattos, additional, Carreiro, Luiza Filizzola Carabetti, additional, Oliveira, Marcelo Gonçalves de, additional, Alves, Marco Túlio Saldanha Victor, additional, Rocha, Maria Clara Brant, additional, Machado, Mariana Campos Duarte, additional, Signorelli, Mariana de Sena Milagres, additional, Morais, Nathália Paim, additional, Carvalho, Paulo Ricardo de Farias, additional, Magalhães, Daniel Vitor Ferreira de, additional, Agulhan, Isabela de Azevedo, additional, Rocha, Victor Maranhão, additional, Pedro, Tainá Torres, additional, Fragoso, Luanny de Andrade Cardoso, additional, CAVALCANTI, MATHEUS DE ALMEIDA MURITIBA PORTELLA, additional, Gomes, Luis Henrique Alves, additional, Girard, Bruna Peixoto, additional, Leite, Anna Carolina Nobre, additional, Wogel, Alícia de Carvalho, additional, Castro, Ana Beatriz de Sousa Pereira Pinto de, additional, Zago, Isabella Ribeiro, additional, Nasser, Leonardo Azevedo, additional, Petry, Maria Guimarães, additional, Guilarducci, Nathália Vital, additional, Gomes, Maria Beatriz Mares, additional, Domingos, Samira Olivé, additional, Melo, Victoria Rachel Rotsen de, additional, Ferreira, Vitória Froes Miraglia Martins, additional, Lacerda, Yasmim Mesquita, additional, Santos, Yasmin Brito, additional, Menezes, Pedro Versiani dos Anjos, additional, Canela, Heliara Maria S., additional, Magri, José Eduardo, additional, Prado, Reuder Pereira, additional, Jacob, Isabela Matos Augusto, additional, Nunes, Caroline Baby, additional, Maximiano, Mariana Letícia de Bastos, additional, Souza, Ana Carolina de Azevedo, additional, Santos, Nathanael Alves dos, additional, Schwambach, Aracele Franzen, additional, Castro, Luis Henrique Almeida, additional, Ferreira, Glória Maria Granjeiro, additional, Salvador, Dailyt Guimarães, additional, and Silva, Álvaro Bulhões da, additional

Published
2021
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5. Taurine deficiency as a driver of aging

Author

P, Singh, primary, K, Gollapalli, additional, S, Mangiola, additional, D, Schranner, additional, MA, Yusuf, additional, M, Chamoli, additional, SL, Shi, additional, B, Lopes Bastos, additional, T, Nair, additional, A, Riermeier, additional, EM, Vayndorf, additional, JZ, Wu, additional, A, Nilakhe, additional, CQ, Nguyen, additional, M, Muir, additional, MG, Kiflezghi, additional, A, Foulger, additional, A, Junker, additional, J, Devine, additional, K, Sharan, additional, SJ, Chinta, additional, S, Rajput, additional, A, Rane, additional, P, Baumert, additional, M, Schonfelder, additional, F, Iavarone, additional, G, di Lorenzo, additional, S, Kumari, additional, A, Gupta, additional, R, Sarkar, additional, C, Khyriem, additional, AS, Chawla, additional, A, Sharma, additional, N, Sarper, additional, N, Chattopadhyay, additional, BK, Biswal, additional, C, Settembre, additional, P, Nagarajan, additional, KL, Targoff, additional, M, Picard, additional, S, Gupta, additional, V, Velagapudi, additional, AT, Papenfuss, additional, A, Kaya, additional, MG, Ferreira, additional, BK, Kennedy, additional, JK, Andersen, additional, GJ, Lithgow, additional, AM, Ali, additional, A, Mukhopadhyay, additional, A, Palotie, additional, G, Kastenmuller, additional, M, Kaeberlein, additional, H, Wackerhage, additional, B, Pal, additional, and VK, Yadav, additional

Published
2023
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6. INTEGRAL and XMM-Newton observations towards the unidentified MeV source GRO J1411-64

Author

Torres, Diego F., Zhang, Shu, Reimer, Olaf, Barcons, Xavier, Corral, Amalia, Bosch-Ramon, Valenti, Paredes, Josep M., Romero, Gustavo E., Qu, Jin Lu, Collmar, Werner, Schonfelder, V., and Butt, Yousaf

Subjects
Astrophysics
Abstract

The COMPTEL unidentified source GRO J1411-64 was observed by INTEGRAL, and its central part, also by XMM-Newton. The data analysis shows no hint for new detections at hard X-rays. The upper limits in flux herein presented constrain the energy spectrum of whatever was producing GRO J1411-64, imposing, in the framework of earlier COMPTEL observations, the existence of a peak in power output located somewhere between 300-700 keV for the so-called low state. The Circinus Galaxy is the only source detected within the 4$\sigma$ location error of GRO J1411-64, but can be safely excluded as the possible counterpart: the extrapolation of the energy spectrum is well below the one for GRO J1411-64 at MeV energies. 22 significant sources (likelihood $> 10$) were extracted and analyzed from XMM-Newton data. Only one of these sources, XMMU J141255.6-635932, is spectrally compatible with GRO J1411-64 although the fact the soft X-ray observations do not cover the full extent of the COMPTEL source position uncertainty make an association hard to quantify and thus risky. The unique peak of the power output at high energies (hard X-rays and gamma-rays) resembles that found in the SED seen in blazars or microquasars. However, an analysis using a microquasar model consisting on a magnetized conical jet filled with relativistic electrons which radiate through synchrotron and inverse Compton scattering with star, disk, corona and synchrotron photons shows that it is hard to comply with all observational constrains. This and the non-detection at hard X-rays introduce an a-posteriori question mark upon the physical reality of this source, which is discussed in some detail.

Published
2006
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7. Are Ti44-Producing Supernovae Exceptional?

Author

The, L. -S., Clayton, D. D., Diehl, R., Hartmann, D. H., Iyudin, A. F., Leising, M. D., Meyer, B. S., Motizuki, Y., and Schonfelder, V.

Subjects
Astrophysics
Abstract

According to standard models supernovae produce radioactive $^{44}$Ti, which should be visible in gamma-rays following decay to $^{44}$Ca for a few centuries. $^{44}Ti production is believed to be the source of cosmic $^{44}$Ca, whose abundance is well established. Yet, gamma-ray telescopes have not seen the expected young remnants of core collapse events. The $^{44}$Ti mean life of $\tau \simeq$ 89 y and the Galactic supernova rate of $\simeq$ 3/100 y imply $\simeq$ several detectable $^{44}Ti gamma-ray sources, but only one is clearly seen, the 340-year-old Cas A SNR. Furthermore, supernovae which produce much $^{44}Ti are expected to occur primarily in the inner part of the Galaxy, where young massive stars are most abundant. Because the Galaxy is transparent to gamma-rays, this should be the dominant location of expected gamma-ray sources. Yet the Cas A SNR as the only one source is located far from the inner Galaxy (at longitude 112 degree). We evaluate the surprising absence of detectable supernovae from the past three centuries. We discuss whether our understanding of SN explosions, their $^{44}Ti yields, their spatial distributions, and statistical arguments can be stretched so that this apparent disagreement may be accommodated within reasonable expectations, or if we have to revise some or all of the above aspects to bring expectations in agreement with the observations. We conclude that either core collapse supernovae have been improbably rare in the Galaxy during the past few centuries, or $^{44}Ti-producing supernovae are atypical supernovae. We also present a new argument based on $^{44}$Ca/$^{40}$Ca ratios in mainstream SiC stardust grains that may cast doubt on massive-He-cap Type I supernovae as the source of most galactic $^{44}$Ca., Comment: 23 pages, 14 figures, accepted for publication in Astronomy and Astrophysics 2006. Correcting the SN type of Tycho in Table B.1. and add its associated references

Published
2006
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8. COMPTEL Observations of the Gamma-ray Blazars 3C~454.3 and CTA 102 During the CGRO Mission

Author

Zhang, S., Collmar, W., and Schonfelder, V.

Subjects
Astrophysics
Abstract

We have investigated the MeV behaviour of the \gray blazars 3C~454.3 and CTA 102 by analyzing all COMPTEL observations of this sky region during the complete CGRO mission. Both sources are detected by COMPTEL at the upper COMPTEL energies; although their flux estimates may be uncertain by possible minor contribution of nearby unidentified EGRET \gray sources. While CTA 102 was only detected at energies above 10 MeV during the early mission, 3C~454.3 is most significantly detected in the COMPTEL 3-10 MeV band in the sum of all data. Time-resolved analyses indicate a weak (near COMPTEL threshold) but likely steady 3-10 MeV emission over years, being independent of the observed time variability at energies above 100 MeV as observed by EGRET. This energy-dependent variability behaviour suggests different emission mechanisms at work at the two bands. Putting the COMPTEL fluxes in multifrequency perspective (radio to \grays), reveals for both sources the typical two-hump blazar spectra, with a low-energy maximum around the IR and a high-energy maximum at MeV energies. The latter one dominates the energy output across the whole electro-magnetic spectrum. The results of our analyses are discussed in the framework of current blazar modeling., Comment: 19 pages, 11 figures, accepted for publication in A&A

Published
2005
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9. Search for gamma-ray line emission from the radioactive decay of 60Fe with SPI

Author

Knodlseder, J., Cisana, E., Diehl, R., Lichti, G., Harris, M., Jean, P., Kretschmer, K., von Kienlin, A., Roques, J. -P., Schanne, S., Schonfelder, V., Vedrenne, G., Weidenspointner, G., and Wunderer, C.

Subjects
Astrophysics
Abstract

The search for gamma-ray line emission from the radioactive decay of 60Fe figures among the prime scientific objectives of the INTEGRAL mission. 60Fe is believed to be primarily produced in core-collapse supernovae, although other sites, such as carbon deflagration supernovae or intermediate mass AGB stars have also been suggested. We present first results of our search for the 1173 and 1332 keV gamma-ray lines of 60Fe decay in the SPI data of the first mission year. So far we can only report upper flux limits whose levels are determined by systematic uncertainties in the treatment of the instrumental background. Once we understand the background uncertainties better, the SPI data should provide stringent constraints on 60Fe nucleosynthesis in our Galaxy., Comment: 5 pages, to appear in the Proceedings of the 5th INTEGRAL Workshop (Munich, Germany)

Published
2004

10. Early SPI/INTEGRAL contraints on the morphology of the 511 keV line emission in the 4th galactic quadrant

Author

Knodlseder, J., Lonjou, V., Jean, P., Allain, M., Mandrou, P., Roques, J. -P., Skinner, G. K., Vedrenne, G., von Ballmoos, P., Weidenspointner, G., Caraveo, P., Cordier, B., Schonfelder, V., and Teegarden, B. J.

Subjects
Astrophysics
Abstract

We provide first constraints on the morphology of the 511 keV line emission from the galactic centre region on basis of data taken with the spectrometer SPI on the INTEGRAL gamma-ray observatory. The data suggest an azimuthally symmetric galactic bulge component with FWHM of ~9 deg with a 2 sigma uncertainty range covering 6-18 deg. The 511 keV line flux in the bulge component amounts to (9.9+4.7-2.1) 10e-4 ph cm-2 s-1. No evidence for a galactic disk component has been found so far; upper 2 sigma flux limits in the range (1.4-3.4) 10e-3 ph cm-2 s-1 have been obtained that depend on the assumed disk morphology. These limits correspond to lower limits on the bulge-to-disk ratio of 0.3-0.6., Comment: 5 pages, 3 figures, accepted for publication in A&A

Published
2003
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11. An Unidentified Variable Gamma-Ray Source near the Galactic Plane Detected by COMPTEL

Author

Zhang, S., Collmar, W., and Schonfelder, V.

Subjects
Astrophysics
Abstract

We report the detection of an unidentified gamma-ray source near the Galactic plane by the COMPTEL experiment aboard the Compton Gamma-Ray Observatory. The source is detected at a significance level of ~ 7.2 sigma in the energy range 1-3 MeV and at ~ 4.6 sigma in the lower 0.75-1 MeV band in the time period March to July 1995. At energies above 3 MeV are only marginal hints or upper limits obtained. The MeV spectrum has a soft shape. Strong flux variability is found within one year at energies below 3 MeV. Possible counterparts of galactic and extragalactic nature are discussed., Comment: 7 pages including 5 figures, accepted for publication in A&A

Published
2002
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12. COMPTEL Observations of the Gamma-Ray Blazar PKS 1622-297

Author

Zhang, S., Collmar, W., Bennett, K., Bloemen, H., Hermsen, W., McConnell, M., Reimer, O., Schonfelder, V., Wagner, S. J., and Williams, O. R.

Subjects
Astrophysics
Abstract

We report results of observations and analyses on the gamma-ray blazar PKS 1622-297, with emphasis on the COMPTEL data (0.75 - 30 MeV) collected between April 1991 and November 1997. PKS 1622-297 was detected as a source of gamma-rays by the EGRET experiment aboard CGRO in 1995 during a gamma-ray outburst at energies above 100 MeV lasting for five weeks. In this time period the blazar was significantly (~ 5.9 sigma) detected by COMPTEL at 10-30 MeV. At lower COMPTEL energies the detection is marginal, resulting in a hard MeV spectrum. The combined COMPTEL/EGRET energy spectrum shows a break at MeV energies. The broad-band spectrum (radio - gamma-rays) shows that the gamma-ray emission dominates the overall power output. On top of the 5-week gamma-ray outburst, EGRET detected a huge flare lasting for > 1 day. Enhanced MeV emission (10 - 30 MeV) is found near the time of this flare, suggesting a possible time delay with respect to the emission above 100 MeV. Outside the 5-week flaring period in 1995, we do not detect MeV emission from PKS 1622-297., Comment: 10 pages including 9 figures, accepted for publication in A&A

Published
2002
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13. The Crab pulsar in the 0.75-30 MeV range as seen by CGRO COMPTEL

Author

Kuiper, L., Hermsen, W., Cusumano, G., Diehl, R., Schonfelder, V., Strong, A., Bennett, K., and McConnell, M.

Subjects
Astrophysics
Abstract

We present the time-averaged characteristics of the Crab pulsar in the 0.75-30 MeV energy window using data from the imaging Compton Telescope COMPTEL aboard the Compton Gamma-Ray Observatory (CGRO) collected over its 9 year mission. Exploiting the exceptionally long COMPTEL exposure on the Crab allowed us to derive significantly improved COMPTEL spectra for the Crab nebula and pulsar emissions, and for the first time to accurately determine at low-energy gamma-rays the pulse profile as a function of energy. These timing data, showing the well-known main pulse and second pulse at a phase separation of 0.4 with strong bridge emission, are studied together with data obtained at soft/hard X-ray energies from the ROSAT HRI, BeppoSAX LECS, MECS and PDS, at soft gamma-rays from CGRO BATSE and at high-energy gamma-rays from CGRO EGRET in order to obtain a coherent high-energy picture of the Crab pulsar from 0.1 keV up to 10 GeV., Comment: 17 pages, accepted for publication in A&A main journal

Published
2001
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14. COMPTEL Observations of the Blazar PKS 1622-297 during a Gamma-Ray High State in 1995

Author

Zhang, S., Collmar, W., Schonfelder, V., Bloemen, H., Hermsen, W., Ryan, J., Bennett, K., Williams, O. R., and Reimer, O.

Subjects
Astrophysics
Abstract

PKS 1622-297 was detected as a source of gamma-rays by the EGRET experiment at energies above 100 MeV during a gamma-ray outburst June and July 1995. We analyzed the COMPTEL data (0.75 - 30 MeV) of this time period to investigate the behaviour of PKS 1622-297 at lower gamma-ray energies. The blazar is significantly (5.7 sigma) detected by COMPTEL at energies above 10 MeV. Below 10 MeV the source is only marginally (3-10 MeV band) or not (below 3 MeV) detected. The summed MeV spectrum shows a 'hard' (alpha < 2, ~ E^(-alpha)) shape and, if combined with the simultaneous EGRET spectrum, a spectral break at MeV energies is indicated. We present the COMPTEL results (light curves, spectra) and compare them to results derived in neighbouring energy bands, in particular to the EGRET one., Comment: 4 pages including 5 figures, accepted for publication in the proceedings of the 4th INTEGRAL workshop, to appear in ESA-SP series

Published
2001

15. Image Reconstruction of COMPTEL 1.8 MeV 26Al Line Data

Author

Knodlseder, J., Dixon, D., Bennett, K., Bloemen, H., Diehl, R., Hermsen, W., Oberlack, U., Ryan, J., Schonfelder, V., and von Ballmoos, P.

Subjects
Astrophysics
Abstract

We present a new algorithm, called Multiresolution Regularized Expectation Maximization (MREM), for the reconstruction of gamma-ray intensity maps from COMPTEL data. The algorithm is based on the iterative Richardson-Lucy scheme to which we added a wavelet thresholding step in order to eliminate image-noise in the reconstruction. The wavelet thresholding explicitly accounts for spatial correlations in the data, and adapts the angular resolution locally, depending on the significance of the signal in the data. We compare the performance of MREM to that of the maximum entropy and the Richardson-Lucy algorithms by means of Monte-Carlo simulations of COMPTEL 1.809 MeV gamma-ray line observations. The simulations demonstrate that the maximum entropy and Richardson-Lucy algorithms provide virtually identical reconstructions which are heavily disturbed by image noise. MREM largely suppresses this noise in the reconstructions, showing only the significant structures that are present in the data. Application of MREM to COMPTEL 1.8 MeV gamma-ray line data results in a 1.809 MeV sky map that is much smoother than the maximum entropy or Richardson-Lucy reconstructions presented previously. The essential features of this map are (1) an asymmetric galactic ridge emission reaching from l=45 deg to l=240 deg, (2) a bright localised emission feature in the Cygnus region around (l,b)=(80 deg,0 deg), (3) two emission spots at l=317 deg and l=332 deg situated in the galactic plane, and (4) an extended emission region around (l,b)=(160 deg, 0 deg). Comparison of the MREM map to the simulated reconstructions demonstrates that the 1.809 MeV emission is confined to the galactic plane., Comment: 13 pages, 7 figures, A&A, in press

Published
1999

16. Possibility of the detection of classical novae with the shield of the INTEGRAL-spectrometer SPI

Author

Jean, P., Gomez-Gomar, J., Hernanz, M., Jose, J., Isern, J., Vedrenne, G., Mandrou, P., Schonfelder, V., Lichti, G. G., and Georgii, R.

Subjects
Astrophysics
Abstract

The shield of the INTEGRAL spectrometer provides a large detection area with a wide field-of-view. Calculations have been performed to check whether the temporal analysis of the counting rate of the SPI anticoincidence allows the detection of explosions of novae. The background rate of the shield as well as its response to gamma-ray have been modelled with monte-carlo simulations. Accounting for uncertainties in the rate of novae, their distribution in the Galaxy and their light curves in hard X-ray domain, the number of nova explosions detectable with this method during the INTEGRAL mission, is estimated. Such observationnal mode will allow to improve our knowledge on nuclear runaway in novae. Since the maximum of magnitude in the visible happens later than in gamma-ray, SPI will provide alert for optical observations., Comment: 4 pages, 4 figures, to appear in "3rd INTEGRAL Workshop: The Extreme Universe", Taormina (Italy)

Published
1999

17. A New Look at Image Reconstruction of COMPTEL 1.8 MeV Data

Author

Knodlseder, J., Dixon, D., Diehl, R., Oberlack, U., von Ballmoos, P., Bloemen, H., Hermsen, W., Iyudin, A., Ryan, J., and Schonfelder, V.

Subjects
Astrophysics
Abstract

Deconvolving COMPTEL gamma-ray data into images presents a major methodological challenge. We developed a new algorithm called Multiresolution Regularized Expectation Maximization (MREM), which explicitly accounts for spatial correlations in the image by using wavelets (Dixon et al. 1998). We demonstrate that MREM largely suppresses image noise in the reconstruction, showing only significant structures that are present in the data. Application to 1.8 MeV data results in a sky map that is much smoother than the maximum entropy reconstructions presented previously, but it shows the same characteristic emission features which have been established earlier., Comment: 4 pages, 1 figure, Proc. of the 3rd INTEGRAL workshop, Taormina

Published
1999

18. Assessment of Tracers of 1.8 MeV Emission

Author

Knodlseder, J., Diehl, R., Oberlack, U., von Ballmoos, P., Bloemen, H., Hermsen, W., Iyudin, A., Ryan, J., and Schonfelder, V.

Subjects
Astrophysics
Abstract

We examined the question of a possible correlation between 1.8 MeV emission and intensity distributions observed at other wavelengths by comparing the 1.8 MeV data to an extended set of all-sky maps, covering the entire explored wavelength range from the radio band up to high-energy gamma-rays. This analysis revealed that tracers of the old stellar population or the local interstellar medium provide only a poor description of the data. Tracers of the young stellar population considerably improve the fit. Residuals are minimized for the free-free emission map obtained by the DMR at microwave wavelengths and the 158 um fine-structure line map of C+ observed by FIRAS. Within the statistics of the present data, both maps provide an overall satisfactory fit. We therefore conclude that adequate tracers of 26Al sources have now been identified. Implications for 26Al source types are discussed (see also Knodlseder, these proceedings)., Comment: 4 pages, 1 figure, Proc. of the 3rd INTEGRAL workshop, Taormina

Published
1999

19. Revisão da literatura sobre as principais drogas vigentes para tratamento da obesidade no Brasil

Author

Pizzol, Matheus Henrique, primary, Geronimo, Renan Miguel Porcini, additional, Pereira, Gerci Leal, additional, Rodrigues, Adriene Gontijo, additional, Do Amaral, Fernando Henrique Faria, additional, Gomes Neto, Carlos Manoel, additional, De Oliveira, Talles Matos, additional, Ceccon, Robson, additional, Silva, Silvana Oliveira, additional, Guimarães, Bianca Batista Santos, additional, Machado, Carolina Juliana Pereira, additional, E Silva, Náira Francine Silva, additional, Dias, Bárbara Incerte, additional, Olimpio, Yuri Moisés Taketomi, additional, Gomes, Camila Alcântara de Carvalho Souza, additional, Junior, Mario Jose Battistella, additional, and De Proença, Pamela Schonfelder, additional

Published
2023
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21. Introducing HyPeak: An international network on hydropeaking research, practice, and policy

Author

Alp, M, Batalla, RJ, Dolores Bejarano, M, Boavida, I, Capra, H, Carolli, M, Casas-Mulet, R, Costa, MJ, Halleraker, JH, Hauer, C, Hayes, DS, Harby, A, Noack, M, Palau, A, Schneider, M, Schonfelder, L, Tonolla, D, Vanzo, D, Venus, T, Vericat, D, Zolezzi, G, Bruno, MC, Alp, M, Batalla, RJ, Dolores Bejarano, M, Boavida, I, Capra, H, Carolli, M, Casas-Mulet, R, Costa, MJ, Halleraker, JH, Hauer, C, Hayes, DS, Harby, A, Noack, M, Palau, A, Schneider, M, Schonfelder, L, Tonolla, D, Vanzo, D, Venus, T, Vericat, D, Zolezzi, G, and Bruno, MC

Abstract

An increase in the demand for renewable energy is driving hydropower development and its integration with variable renewable energy sources. When hydropower is produced flexibly from hydropower plants, it causes rapid and frequent artificial flow fluctuations in rivers, a phenomenon known as hydropeaking. Hydropeaking and associated hydrological alterations cause multiple impacts on riverine habitats with cascading effects on ecosystem functioning and structure. Given the significance of its ecological and socio‐economic implications, mitigation of hydropeaking requires an inter‐ and transdisciplinary approach. An interdisciplinary network called HyPeak has been conceived to enrich international research initiatives and support hydropower planning and policy. HyPeak has been founded based on exchange and networking activities linking scientists from several countries where hydropeaking has been widespread for decades and numerous studies dedicated to the topic have been carried out. HyPeak aims to integrate members from other countries and continents in which hydropower production plays a relevant role, and grow to be a reference group that provides expert advice on the topic to policy‐makers, as well as researchers, stakeholders, and practitioners in the field of hydropeaking.

Published
2023

25. First Results from NA49 on Pb+Pb Collisions at 158 GeV/Nucleon

Author

Margetis, S., Alber, T., Appelshauser, H., Bachler, J., Bartke, J., Bialkowska, H., Bieser, F., Bloomer, M.A., Blyth, C.O., Bock, R., Bormann, C., Brady, F.P., Brockmann, R., Buncic, P., Caines, H.L., Cebra, D., Chan, P., Cooper, G., Cramer, J.G., Cramer, P.B., Csato, P., Derado, I., Dunn, J., Eckardt, V., Eckhardt, F., Euler, S., Ferguson, M.I., Fischer, H.G., Fodor, Z., Foka, P., Freund, P., Fuchs, M., Gal, J., Gazdzicki, M., Gladysz, E., Grebieszkow, J., Gunther, J., Harris, J.W., Heck, W., Hegyi, S., Hill, L.A., Huang, I., Howe, M.A., Igo, G., Irmscher, D., Jacobs, P., Jones, P.G., Kadija, K., Kecskemeti, J., Kosiec, J., Kowalski, M., Kuhmichel, A., Lasiuk, B., Mitchell, J.W., Mock, A., Nelson, J.M., Odyniec, G.J., Palinkas, J., Palla, G., Panagiotou, A.D., Petridis, A., Piper, A., Poskanzer, A.M., Prindle, D.J., Puhlhofer, F., Rauch, W., Renfordt, R., Retyk, W., Ritter, Hans G., Rohrich, D., Rudolph, H., Runge, K., Sandoval, A., Sann, H., Schaefer, E., Schmitz, N., Schonfelder, S., Seyboth, P., Seyerlein, J., Sikler, F., Skrzypczak, E., Stefansky, P., Stock, R., Stroebele, H., Szentpetery, I., Sziklai, J., Toy, M., Trainor, T.A., Trentalange, S., Vassiliou, M., Vesztergombi, G., Vranic, D., Wenig, S., Whitten, C., Wienold, T., Wood, L., Zimanyi, J., Zhu, X.-Z., and Zybert, R.

Published
1995

26. A modified growth function with interpretable parameters applied to the age-height relationship of individual trees

Author

Fischer, Christoph and Schonfelder, Egbert

Subjects
Mathematical models -- Usage, Forests -- Models, Trees (Plants) -- Models -- Growth, Company growth, Earth sciences
Abstract

Growth functions frequently used in forestry have in common that among the model parameters to be estimated, only the asymptote is expressed in the dimensions of the input data. By contrast, parameters determining rate and shape of the curve often exhibit indefinite scales. This might cause problems in specifying adequate starting values and in parameter interpretation. We present a mathematical derivation to obtain a modified growth function based on the four-parameter Richards function. Two of the rate and shape parameters were replaced by new parameters directly related to the growth process: time of maximum growth and maximum growth rate. Both the original model and its modified form were fitted to individual-tree height-age data from the National Forest Inventory in Germany. The modified function has several advantages: (i) easier interpretability of model parameters, (ii) easier specification of starting values, (iii) improved linear behavior allowing for more reliable asymptotic inferences and for better convergence, and (iv) reduced correlation between model parameters. As a further benefit, the presented model allows for deriving biologically interpretable forms of the Gompertz function, the von Bertalanffy function, and the logistic function. Based on the results, we suggest using the modified function provided for further applications in growth modeling. Key words: reparametrization, nonlinearity, nonparametric bootstrap, individual-tree growth, Richards function. Les fonctions de croissances frequemment utilisees dans le domaine forestier ont en commun que, parmi les parametres du modele a estimer, seule l'asymptote est exprimee dans les dimensions des donnees d'entree. En revanche, les parametres qui determinent le taux de croissance et la forme de la courbe presentent souvent des echelles indefinies. Cela pourrait causer des problemes au moment de specifier des valeurs de depart adequates et pour l'interpretation des parametres. Nous presentons une derivation mathematique pour obtenir une fonction de croissance modifiee fondee sur la fonction de Richards a quatre parametres. Deux des parametres controlant le taux de croissance et la forme ont ete remplaces par de nouveaux parametres directement lies au processus de croissance: le moment ou la croissance est maximale et le taux de croissance maximal. Le modele original et sa forme modifiee ont tous deux ete ajustes aux donnees de hauteur et d'age d'arbres individuels de l'Inventaire forestier national en Allemagne. La fonction modifiee presente plusieurs avantages: (i) interpretation plus facile des parametres du modele; (ii) valeurs de depart plus facile a specifier; (iii) amelioration du comportement lineaire permettant des inferences asymptotiques plus fiables et une meilleure convergence; et (iv) correlation reduite entre les parametres du modele. Comme autre avantage, le modele presente permet de deriver les formes biologiquement interpretables des fonctions de croissance de Gompertz, de von Bertalanffy et logistique. Sur la base de ces resultats, nous suggerons d'utiliser la fonction modifiee que nous presentons pour d'autres applications en modelisation de la croissance. [Traduit par la Redaction] Mots-cles: reparametrage, non-linearite, reechantillonnage non parametrique, croissance individuelle des arbres, fonction de croissance de Richards., 1. Introduction Growth functions describe the change in size of an individual or population with age or initial size. The relationship between the predictor and the response follows the general [...]

Published
2017
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27. Transverse Energy Production in {sup 208}Pb+Pb Collisions at 158 GeV per Nucleon

Author

Margetis, S., Alber, T., Appelshauser, H., Bachler, J., Bartke, J., Bialkowska, H., Bieser, F., Bloomer, M.A., Blyth, C.O., Bock, R., Bormann, C., Brady, F.P., Brockmann, R., Buncic, P., Caines, H.L., Cebra, D., Chan, P., Cooper, G.E., Cramer, J.G., Cramer, P.B., Csato, P., Derado, I., Dunn, J., Eckardt, V., Eckhardt, F., Euler, S., Ferguson, M.I., Fischer, H.G., Fodor, Z., Foka, P., Freund, P., Fuchs, M., Gal, J., Gasdzicki, M., Gladysz, E., Grebieszkow, J., Gunther, J., Harris, J.W., Heck, W., Hegyi, S., Hill, L.A., Huang, I., Howe, M.A., Igo, G., Irmscher, D., Jacobs, P., Jones, P.G., Kadija, K., Kecskemeti, J., Kowalski, M., Kuhmichel, A., Lsdiuk, B., Mitchell, J.W., Mock, A., Nelson, J.M., Odyniec, G.J., Palinkas, J., Palla, G., Panagiotou, A.D., Petridis, A., Piper, A., Poskanzer, A.M., Prindle, D.J., Puhlhofer, F., Rauch, W., Renfordt, R., Retyk, W., Ritter, Hans G., Rohrich, D., Rudolph, H., Runge, K., Sandoval, A., Sann, H., Schafer, E., Schmitz, N., Schonfelder, S., Seyboth, P., Seyerlein, J., Sikler, F., Skrzypczak, E., Stock, R., Stroebele, H., Szentpetery, I., Sziklai, J., Toy, M., Trainor, T.A., Trentalange, S., Vassiliou, M., Vesztergombi, G., Vranic, D., Wenig, S., Whitten, C., Wienold, T., Wood, L., Zimanyi, J., Zhu, X.-Z., and Zybert, R.

Published
1994

29. Incidence, prevalence, and comorbidities of juvenile idiopathic arthritis in Germany: a retrospective observational cohort health claims database study

Author

Horneff, Gerd, Borchert, Julia, Heinrich, Ria, Kock, Simon, Klaus, Pascal, Dally, Heike, Hagemann, Christine, Diesing, Joanna, Schonfelder, Tonio, Horneff, Gerd, Borchert, Julia, Heinrich, Ria, Kock, Simon, Klaus, Pascal, Dally, Heike, Hagemann, Christine, Diesing, Joanna, and Schonfelder, Tonio

Abstract

Background Juvenile idiopathic arthritis (JIA) describes heterogenous categories of chronic inflammatory rheumatic conditions of unknown origin in children and adolescents. Epidemiological data in the literature vary, depending on geographic location, ethnicity and the case definition used. We evaluated epidemiology, especially that of the categories defined by the International League of Associations for Rheumatology (ILAR). Methods Using data from two different longitudinal health claims databases (WIG2 and InGef) from January 1(st), 2013 to December 31(st), 2019, we looked at patients aged 2 to 15 years old with at least one main inpatient or two secondary inpatient/verified outpatient ICD-10 diagnoses in at least two different quarters within one calendar year. We calculated prevalence and incidence (per 100,000 patients) and extrapolated data to the entire German population, looking at differences in gender and age groups. Additionally, we collected data on other not necessary comorbidities in our JIA patient population. Results Of the 3-4 million patients in the databases (respectively) in 2018, we found a total of 546 (WIG2) and 849 (InGef) patients that met our JIA case definition, with an incidence of 34 (29-41) and 60 (53-67) and prevalence of 133 (122-145) and 168 (157-179). Both incidence and prevalence throughout the age range were mostly higher in females than males, however the difference between females and males increased with increasing age. Of the ILAR categories, oligoarthritis was the most prevalent (70 and 91 per 100,000), with about half of our JIA patients in this category, followed by undifferentiated arthritis (49 and 56 cases per 100,000) and rheumatoid factor negative (RF-) (31 and 39 per 100,000). Incidence in 2018 was the highest in these three categories. Atopic dermatitis, vasomotor and allergic rhinitis, and uveitis were the pre-defined comorbidities seen most often in both databases. Conclusion This study provides current incidence

Published
2022

31. REVASCULARIZAÇÃO MIOCÁRDICA NO CONTEXTO DA DOENÇA ARTERIAL CORONARIANA ESTÁVEL

Author

RENAN MIGUEL PORCINI GERONIMO, MAURICIO MENEZES BARBOSA JÚNIOR, LUÍZ TEIXEIRA DA SILVA JÚNIOR, ROBSON CECCON, MATHEUS YAN SOBRAL TEIXEIRA OLIVEIRA, RENATO CASTILHO DOS SANTOS, SILVANA OLIVEIRA TOMÉ, GISELE GOMES BRANDÃO, RAPHAELA NOGUEIRA DUTRA, GEOVAM NATAL LIMA RAMOS, ANA KAROLINE DE ALMEIDA MACHADO, GUSTAVO BECKERT TRINKEL, PAMELA GARCIA SCHONFELDER DE PROENÇA, CHRISTIAN FERREIRA GADBEN, and LIDIA FARIA TEIXEIRA

Published
2022

32. HEMORRAGIA PÓS-PARTO E O SEU MANEJO MÉDICO, MINIMAMENTE INVASIVO E POR LAPAROTOMIA

Author

MATHEUS HENRIQUE PIZZOL, MARIO JOSÉ BATTISTELLA JUNIOR, LUÍZ TEIXEIRA DA SILVA JÚNIOR, LARISSA PEREIRA DUARTE, FERNANDO HENRIQUE FARIA DO AMARAL, HAYANE SOUZA DE OLIVEIRA, GEOVAM NATAL LIMA RAMOS, ANA KAROLINE DE ALMEIDA MACHADO, BARBARAH ALBUQUERQUE BENTES, BEATRIZ MACACARI, SIDNEY JUNIOR VIEGAS DE MELO, BÁRBARA INCERTE DIAS, ANA MARIA DA SILVA, and PÂMELA GARCIA SCHONFELDER DE PROENÇA

Published
2022

33. AVALIAÇÃO ECOCARDIOGRÁFICA DA VÁLVULA MITRAL

Author

MAURÍCIO MENEZES BARBOSA JÚNIOR, LUÍZ TEIXEIRA DA SILVA JÚNIOR, ROBSON CECCON, LIDIA FARIA TEIXEIRA, ISADORA GUIMARAES DA ROCHA, MATHEUS YAN SOBRAL TEIXEIRA OLIVEIRA, SILVANA OLIVEIRA TOMÉ, RENATO CASTILHO DOS SANTOS, GISELE GOMES BRANDÃO, RAPHAELA NOGUEIRA DUTRA, CAETANO PASCHOAL VIEIRA MILANI, MUNIR IBEN ARFOX, YASMIN SÁ DE MELO, CAROLINE DIB DE OLIVEIRA AYETA, and PÂMELA GARCIA SCHONFELDER DE PROENÇA

Published
2022

34. Wounds and Words : Childhood and Family Trauma in Romantic and Postmodern Fiction

Author

Schonfelder, Christa

Subjects
Literary Criticism / European / English, Irish, Scottish, Welsh, Literary Criticism
Abstract

Trauma has become a hotly contested topic in literary studies. But interest in trauma is not new; its roots extend to the Romantic period, when novelists and the first psychiatrists influenced each others' investigations of the 'wounded mind'. This book looks back to these early attempts to understand trauma, reading a selection of Romantic novels in dialogue with Romantic and contemporary psychiatry. It then carries that dialogue forward to postmodern fiction, examining further how empirical approaches can deepen our theorizations of trauma. Within an interdisciplinary framework, this study reveals fresh insights into the poetics, politics, and ethics of trauma fiction.

Published
2013

35. Trauma e Emergência - Teoria e Prática

Author

ANNA JÚLIA ARRAES ALVES DE SOUZA, NAYARA DA SILVA GALDINO, Kátia Talita dos Santos Barros, Rafaela Martins Santos, Rafaella Storck Gomes, Rodolfo Lima Araújo, Matheus Felipe Apolinário, Matheus Augusto Coelho Quitete, ALESSANDRA SOICA GORINO, Luisa Tavares de Azevedo, Mariana Ramos Peixoto Melo, Sarah Franco Nogueira Mesquita, Pedro Lucas Apolinário, João Pedro Costa Apolinário, João Felipe Tinto Silva, Jaqueline Brito Da Costa, Iracema Silva Da Costa, Laine Da Costa Almeida Barboza, Raiane Lira Dos Santos, Valéria Fernanda Da Silva Almeida, Alaine Dos Santos Silva Martins, Dayla Soeiro Homem, Aline Alves da Silva, Klecia Nogueira Máximo, Shirley De Vasconcelos Bonfim Brito, Viviane Dos Santos Melo, Celice Ruanda Oliveira Sobrinho, LYNNA STEFANY FURTADO MORAIS, Thays Pereira Rodrigues, Taize Vieira Da Cruz, Luiz Felipe Guimarães Gualberto Moreira, Lucas dos Santos Queiroga, Luís Eduardo Oliveira Figueira, Lívia Corrêa Ramalho, Lara Reggiani Nepomuceno, Lavínia Vasconcellos Patrus Pena, Lucas Jorge Nardelli, João Victor Silva Abreu, Carolina Monte Santo Burdman Pereira, Idahil Pereira dos Reis, Guilherme Dantas Borges, Ana Izabel Aparecida Vieira, Laura Marques Barros, Regina Lígia Gomes Ferreira, Débora Francielle Dias, Eliano Atanázio Vieira, Pedro Miguel Calife da Luz, Bruno Augusto Lopes, Mariana Pereira Barbosa Silva, Layanne Cavalcante de Moura, Thiago Evencio Mendes Luz, Caio Matheus Feitosa de Oliveira, André Luis Mendes Cavalcanti, Salomão Xavier Sobrinho, Luís Eduardo Arcoverde Nogueira Brayner, Wanderley Lopes Resende, Maria Eduarda Martins Nogueira, Amanda Costa Maciel, Lívia Gonçalves de Lima, Jadson Viana Barreto, Joelma Maria dos Santos da Silva Apolinário, Cleiciane remigio nunes, Yonara Cristiane Ribeiro, Camilla Tozi Francischetto, Camila Duarte Lage dos Santos, Danielle Lopes da Silva, Camila do Carmo Said, Marcella Dovera Soares Rolim, Luiza Silva Lopes, Julia Felix Raposo Martins da Cunha, Barbara dos santos Simões, Monique Benemérita Vilela Gomes, Miguel Godeiro Fernandez, Monica Suzana Alves Vilela, José Aderval Aragão, Aglaé Travassos Albuquerque, Victória Rezende De Brito, Felipe Matheus SantAnna Aragão, Iapunira Catarina SantAnna Aragão, Francisco Prado Reis, Fabiana Koupak, MAICON HENRIQUE LENTSKC, Duane Casagrande, Maria Regiane Trincaus, Pollyanna Bahls de Souza, TATIANE BARATIERI, Leticia Gramazio Soares, Raul Henrique de Oliveira Pinheiro, Bruno Bordin Pelazza, ERICA DE BRITO PITILIN, Kelly Holanda Prezotto, Marcos Maciel da Silva, Matheus da Cunha Paris, Paula Costa Vieira Paiva, Tiago Silva e Carvalho, Giorgia Janaína S. Pires da Silva, André Versiani Caldeira Rocha, Camila Bruck de Siqueira, Marta Bhering Pereira de Souza, Victoria Caroline Silva Carvalho, Saulo Guimarães Moreira, Vitor Hugo Rocha Caldas, Yasmin Sotero Coimbra, Isabella Cardoso Queiroz, Isadora rosa Maia, João Victor Teodoro Pires de Barros, Karine Felipe Martins, Yuri Vasconcellos Vallim, Beatriz Rosa Garcia, Branca Lopes da Silva Guedes, Daniele da Rosa Fraga, Gabriela de Souza Rusch, Gabriella Picoli dos Santos Faustino, Marcus Vinicius Menezes Portela, Maria Heloisa de Albuquerque Calenzo Lins, Maria Luísa Rabelo Quadros, Maria Luíza da Silva Veloso, Marina Cavalcante Rodrigues de Aguiar, Roberto Oliveira Miaki, Serginara Cristina Flexa Pereira da Silva, Yara Fernandes Ribeiro de Castro, Bruno Cezario Costa REIS, Weberton Dorásio Sobrinho, Luciana Fernandes Rover, David Emanuel Lima de Carvalho, Camila Medeiros Vieira, Isabella Stéfanny de Freitas Postigo, Natália Martins de Lima, Poliana Silva Ferreira, Juliana Reis de Sousa Zacarias, Ana Beatriz Doufem Kato, Karoline de Oliveira Lins Souto, Carla Resende Vaz Oliveira, Felipe Junksztejn Lacerda, Gabriela Lima Cordeiro, Sarah de Maciel Leite, Wesley Cristian Ferreira, Monique Camargo, Raquel dos Santos Vieira, Gabriela Lachter Zusman, Amanda Rocha Fernandes da Silva, Jessica Abdala Lima, Beatriz Souza Bastos, Maria Eduarda Fernandes Nunes, Bruno Cezario Costa Reis, Milena Rafaela Pinto Moraes de Souza, Yalle Moraes Souza Ramos, Laura Rasul de Lima, Isabela Matos Augosto Jacob, Gabrieli Casara Carvalho da Costa, Mateus Vinicius Pedrotti, João Victor Magalhães Scopel, Regina Bicalho Gomes de Faria, Guilherme Fonseca Graciano, Igor Marques Jordão, Ítalo Henrique dos Santos, João Victor Silva Ribeiro, Leonardo Barbosa Ribeiro, Mônica Aramuni Gonçalves, Pedro Humberto Gomes de Freitas, Thais de Oliveira Rodrigues, Vanuza Regina Lommez de Oliveira, Victor Hugo Martins Paula da Silva, Yuri Martins Silva, Natália Fenner Pena, Márcio Weissheimer Lauria, Gabriel Irismar Rodrigues Schwamback, Brenda dos Santos Rodrigues, Beatriz Maria Graça Ivankovics, Camilla Geny Leseux Canto, Daniele de Oliveira Luna, Gabriela Vargas Carneiro, Guilherme Gomes Pinto, Jamila Xavier de Sousa, Lucca Dias Mosconi, Bernardo Jardim Guimarães, Jessica Ariane Silva Valverde, Maria Luisa Pedigoni Ponce, Rafael Tessari Mariconi, Sofia Borini Avelar Mattar, Wilson Santana Silva, Álvaro Martins Gabriel Isaac, Marilene Ferraz Cavalieri, Gabriel Braga Pereira, Bruno Vieira Soares, Larissa de Menezes Cabral, Suellen Duarte Vieira, Matheus Ribeiro Bermal, João Luiz Chaves Ferreira Leite, Alcides Eduardo Eibel, Caetano Paschoal Vieira Milani, Joselita Brito de Oliveira Vieira, Raimundo José Pelegrini, Eliphas Levi Assumpção Egg Gomes, Pâmela Garcia Schonfelder de Proença, WILSON SANTANA SILVA, Lidia Carneiro de Souza, Vívian Moreira de Carvalho, Lucas Miranda da Cunha, Lílian Moreira de carvalho, Gabriel Andrade Bonanno Carvalho, Ana Clara Ribeiro Araújo Paiva, Pedro Henrique Martins Mineiro, Túlio Bittencourt Amaral, Arthur Mendes Gasperini, Mariana Almeida de Oliveira, Carlos Artur Benício, Gabriela Ferreira Buzollo, Thiago Barbosa Fernandes, Ana Flávia Barbosa Fernandes, Thais Carolina Fernandes de Castro, Victoria de Paula Pereira, Pedro Arthur Moreira Aredes, Ana Luísa Nunes Ribeiro, Vanessa Herculano Toledo, Ana Beatriz Barreto Marques, Lorena de Pinho Barrilao, Ingrid Grazielle da Silva Marciano, Kennedy Martinez de Oliveira, Caio Pluvier Duarte Costa, Bernardo Brandão Barbosa, Samuel Vitorio Braga, Thiago Souza de Mello, Alice Freitas Macedo, Amanda Amorim Mugayar, Felipe Corrêa Massahud, Ana Sofia Sousa Ribeiro, Carol Baby Nunes, Marianna Letícia de B. Maximiano, Beatriz Carvalho de Oliveira, Ana Carolina Azevedo Souza, Pedro Henrique de M. Luvizotto, Giovanna Aparecida Balarini Lima, Alexandra Secreti Prevedello, Bárbara Martins Mello de Oliveira, Daniela Rambaldi Mileti, Dara Campos de Oliveira, Geisa Maria Lourenço Silva, Isabela Fialho Vitti, Pedro Martins Oliveira, Rafaela Gonçalves Dias, Rayssa Victória Couto e Souza, Giuliana Leandro de Sousa Freitas, Artur Alexandre de Oliveira, Nathanael dos Santos Alves, Camila Araújo Oliveira, Marcos Antônio Moraes Veras, Isabelle Brito Souza, Abrahão Lincoln Alves Cunha, Raí Emanuel da Silva, Felipe Emannuel Alvino de Jesus, Ingredy Lopes dos Santos, Breno Gonçalves Pinheiro, Jhoana Darc Lopes de Sousa, Vanessa G De Sousa, Jéssica Maria Teles Souza, Ayslan Batista Barros, Thiago Nobre Gomes, Pedro Henrique Fonseca da Silva, Debora Giachini Lenhardt, Gabriel Moreira Romão, Beatriz Olenski Braun, Gabriela Mayumi Uehara, Pablo Oliveira da Silva, Isabela Yurie Yamada, Henrique Toshio Fujizawa Tanaka, Mateus Scaliante Melo, Heloísa Geminiano, Júlia Assis Gonçalves, Raphael Nardelli De Mattos, Ricardo Silva Gastão Morais, Rodrigo Tavares Gonçalves, Adolfo Edson Souza Paiva, AMANDA SIMÕES SANTOS, Ana Carolina Luquezi Corato, Elisa Moraes Carvalho, Emanuel Tiso de Araújo Diniz, Helena Costa Pereira, Isadora Fernandes Dias de Oliveira, Leonardo Júnior Matheus de Aquino, Luiza Ferraz Mangini, Maria Luiza Cobra Vilela, Otho Melo de Figueiredo, Renan Israel Reis, Ayana Rocha Pôrto Mousinho, Pedro Vinícius Teles Gomes, Matheus Neres Batista, Edson Ferreira de Oliveira, Osmar Nascimento Silva, Elisama Pereira Pinheiro, Joel Alves de Sousa, Ana Júlia Vieira, JEHOVAHNNA ANTTONIONI SANTOS, Lavínia Arruda Spósito, Ana Clara Puglia, Lorena Ramos Moral, Anna Luiza Gonçalves Moreira, Gabriel Sousa de Freitas Abreu, Marcella Maciel Rios, Anna Laura Caetano Costa, Valdemiro Freitas, Andressa Fernanda Dos Santos Melo oliveira, Ana Clara Silva de Alencar, João Gabriel Duarte Santos, Emanuely Gomes de Pádua Sá, Ana Carla Cardoso Costa, Sandara Cardoso Muniz, Sahda Elouf Simão, Kauanna Layla Marques Cavalcanti de Oliveira, Cibele Corrêa Mendes, João Victor Carvalho Duarte, Maria Isabella Farias de Araújo, Gloria Maria Grangeiro Gerreira, Lays Samara da Costa Silva e Silva, Dailyt Salvador Guimarães, Fabiane Weber Garcia, Andréia Lara Lopatko Kantoviscki, Julia Deolinda Lustosa, Sheila Ferreira dos Santos, Maria Gabriela Lisboa, Flávia Coutinho Loureiro Ribeiro, Maria Clara Almeida Peixoto, Arthur Barbosa Santos, Fernanda Machado Couto, Alexia Cristina Soares Dos Reis, Rita de Cássia SILVA, Rafael Cota Andrade Ferreira De Souza, Leticia Santana Domiciano, Camila Godinho, Laura Portela Alves, Letícia de Oliveira Santos, Letícia Diniz Santos, Luisa de Aguiar Magalhães, Luisa de Sousa Mattos Murta, Luiza Filizzola Carabetti Carreiro, Marcelo Gonçalves de Oliveira, Marco Túlio Saldanha Victor Alves, Maria Clara Brant Rocha, Mariana Campos Duarte Machado, Mariana de Sena Milagres Signorelli, Nathália Paim Morais, Paulo Ricardo de Farias Carvalho, Daniel Vitor Ferreira de Magalhães, Isabela de Azevedo Agulhan, Victor Maranhão Rocha, Tainá Torres Pedro, Luanny de Andrade Cardoso Fragoso, MATHEUS DE ALMEIDA MURITIBA PORTELLA CAVALCANTI, Luis Henrique Alves Gomes, Bruna Peixoto Girard, Anna Carolina Nobre Leite, Alícia de Carvalho Wogel, Ana Beatriz de Sousa Pereira Pinto de Castro, Isabella Ribeiro Zago, Leonardo Azevedo Nasser, Maria Guimarães Petry, Nathália Vital Guilarducci, Maria Beatriz Mares Gomes, Samira Olivé Domingos, Victoria Rachel Rotsen de Melo, Vitória Froes Miraglia Martins Ferreira, Yasmim Mesquita Lacerda, Yasmin Brito Santos, Pedro Versiani dos Anjos Menezes, Heliara Maria S. Canela, José Eduardo Magri, Reuder Pereira Prado, Isabela Matos Augusto Jacob, Caroline Baby Nunes, Mariana Letícia de Bastos Maximiano, Ana Carolina de Azevedo Souza, Nathanael Alves dos Santos, Aracele Franzen Schwambach, Luis Henrique Almeida Castro, Glória Maria Granjeiro Ferreira, Dailyt Guimarães Salvador, and Álvaro Bulhões da Silva

Published
2021

39. Iron Losses Calculation in Non-Harmonic Power Supply

Author

Vladimir Kindl, Bohumil Skala, Jan Laksar, and Tristan Schonfelder

Subjects
Magnetic circuit, Physics, Harmonics, Magnet, Harmonic, Waveform, Mechanics, Saturation (magnetic), Flux linkage, Voltage
Abstract

The non-harmonic input voltage waveform becomes more frequent with the increasing interest in the multiphase machines; the injecting of higher harmonics is used to the decrease of the saturation of the machine. The non-harmonic flux linkage waveform affects the total iron losses. Presented paper deals with the usage of the modified Steinmetz equation (MSE) used to the calculation of the iron losses. The analytical-numerical tool including the nonlinearity of the magnetic circuit and the dynamic BH curve is presented. Different configurations of input voltage and magnetic material properties are analyzed and the results are compared with the analytical calculation and finite element analysis.

Published
2020

41. A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network

Author

Menendez, Daniel, Krysiak, Oliver, Inga, Alberto, Krysiak, Bianca, Resnick, Michael A., and Schonfelder, Gilbert

Subjects
Neovascularization -- Research, Genetic polymorphisms -- Structure, Genetic polymorphisms -- Research, Cancer cells -- Structure, Cancer cells -- Research, Science and technology
Abstract

The VEGF system is essential for angiogenesis. VEGF overexpression frequently correlates with increased microvascularity and metastasis and decreased spontaneous apoptosis. Although a precise mechanism has not been established, studies suggest that VEGF expression is negatively regulated by p53, a master regulator and tumor suppressor. There are no reports of additional components of the VEGF signal transduction pathway being part of the p53 transcriptional network. A target of VEGF, the VEGF receptor 1/flt-1, can regulate growth and migration of endothelial cells and modulate angiogenesis. VEGF appears to be up-regulated in various cancers in which flt-1 may have a role in tumor progression and metastasis. We identified a C-to-T SNP upstream of the transcriptional start site in [approximately equal to] 6% of the people examined. The SNP is located within a putative p53 response element. Only the promoter with the T SNP (FLT1-T) was responsive to p53 when examined with reporter assays or by endogenous gene expression analysis in cell lines with different SNP status. In response to doxorubicin-induced DNA damage, there was clear allele discrimination based on p53 binding at the FLT1-T but not FLT1-C promoters as well as p53-dependent induction of flt-1 mRNA, which required the presence of FLT1-T. Our results establish that p53 can differentially stimulate transcription at a polymorphic variant of the flt-1 promoter and directly places the VEGF system in the p53 stress-response network via flt-1 in a significant fraction of the human population. We suggest that the p53-VEGF-flt-1 interaction is relevant to risks in angiogenesis-associated diseases, including cancer. single-nucleotide polymorphism | genotoxic stress | VEGF receptor | cancer cells

Published
2006

43. Uridine adenosine tetraphosphate: a novel endothelium- derived vasoconstrictive factor

Author

Jankowski, Vera, Tolle, Markus, Vanholder, Raymond, Schonfelder, Gilbert, van der Giet, Markus, Henning, Lars, Schluter, Hartmut, Paul, Martin, Zidek, Walter, and Jankowski, Joachim

Abstract

Author(s): Vera Jankowski [1, 4]; Markus Tolle [1, 4]; Raymond Vanholder [2]; Gilbert Schonfelder [3]; Markus van der Giet [1]; Lars Henning [1]; Hartmut Schluter [1]; Martin Paul [3]; Walter [...]

Published
2005
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44. Judicial independence in Bulgaria: A tale of splendour and misery

Author

Schonfelder, Bruno

Subjects
Justice, Administration of -- Evaluation, Justice, Administration of -- Bulgaria, Judicial process -- Evaluation, International relations, Regional focus/area studies
Abstract

Bulgaria possesses one of the most independent judiciaries of the post-communist world. But the actual performance of the judiciary has failed to match expectations and it is believed to be in a state of crisis since a majority of Bulgarians view courts as unreliable, inefficient and corrupt, the outcome of litigation is highly unpredictable and corruption reaches the upper echelons of the judiciary.

Published
2005

45. Compact sources as the origin of the soft γ-ray emission of the Milky Way

Author

Lebrun, F., Terrier, R., Bazzano, A., Belanger, G., Bird, A., Bouchet, L., Dean, A., Del Santo, M., Goldwurm, A., Lund, N., Morand, H., Parmar, A., Paul, J., Roques, J.-P., Schonfelder, V., Strong, A. W., Ubertini, P., Walter, R., and Winkler, C.

Subjects
Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): F. Lebrun (corresponding author) [1]; R. Terrier [1, 2]; A. Bazzano [3]; G. Bélanger [1]; A. Bird [4]; L. Bouchet [5]; A. Dean [4]; M. Del Santo [3]; A. [...]

Published
2004
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47. An HDR CMOS image sensor with spiking pixels, pixel-level ADC, and linear characteristics

Author

Doge, Jens, Schonfelder, Gert, Streil, Gerhard Thomas, and Konig, Andreas

Subjects
Imaging systems -- Research, Pixels -- Research, Business, Computers and office automation industries, Electronics, Electronics and electrical industries
Abstract

A high dynamic range (HDR) CMOS image sensor architecture based on spiking pixel cells and its first implementation, a linear 128-pixel sensor, is presented. The pulse rate of the pixei cell is proportional to the local light intensity. The pixel cell features a pixel-level analog-to-digital (A/D) conversion by pulse counting. It allows to tradeoff conversion precision versus frame rate. Sample sensor chips have been manufactured using a 0.8-[micro]m double metal CMOS technology, and the test results confirming the feasibility of the chosen approach are reported. Index Terms--CMOS image sensors, high dynamic range, high value resolution, pixel-level analog-to-digital (A/D) conversion.

Published
2002

49. High energy inelastic processes

Author

Schonfelder, John Lawrence

Subjects
530
Abstract

This thesis is a study of high energy inelastic processes. In particular, the main bulk of the text is a report of detailed calculations for some reactions leading to three particle final states. The first chapter is a brief review, of the main features of the experimental situation for high energy inelastic processes. Followed by a brief description of the main theoretical models used to explain the experimental data, viz the peripheral model in its particle exchange and Regge-exchange forms.

Published
1969

50. VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle

Author

Figeac, Nicolas, Mohamed, Abdalla, Sun, Congshan, Schonfelder, Martin, Matallanas, David, Garcia-Munoz, Amaya, Missiaglia, Edoardo, Collie-Duguid, Elaina, De Mello, Vanessa, Pobbati, Ajaybabu, Prueller, Johanna, Jaka Irizar, Oihane, Harridge, Stephen David Royston, Hong, Wanjin, Shipley, Janet, Vargesson, Neil, Zammit, Peter Steven, and Wackerhage, Henning

Subjects
TAZ, Muscle Fibers, Skeletal, Muscle Proteins, Skeletal muscle, WWTR1, Stem cells, Muscle Development, Animals, Cell Differentiation/genetics, Cell Proliferation/genetics, DNA-Binding Proteins/metabolism, Gene Expression Regulation, HEK293 Cells, Humans, Mice, Knockout, Muscle Development/genetics, Muscle Fibers, Skeletal/metabolism, Muscle Proteins/metabolism, Muscle, Skeletal/metabolism, Myoblasts/metabolism, Neoplasms/metabolism, Nuclear Proteins/metabolism, Protein Binding, Transcription Factors/metabolism, Transcriptome/genetics, TEAD, VGLL3, YAP, Myoblasts, Neoplasms, Vgll3, Tead, Yap, Taz, Wwtr1, Skeletal Muscle, Stem Cells, Muscle, Skeletal, Cell Proliferation, Nuclear Proteins, TEA Domain Transcription Factors, Cell Differentiation, DNA-Binding Proteins, Transcriptome, Transcription Factors, Research Article
Abstract

VGLL proteins are transcriptional co-factors that bind TEAD family transcription factors to regulate events ranging from wing development in fly, to muscle fibre composition and immune function in mice. Here, we characterise Vgll3 in skeletal muscle. We found that mouse Vgll3 was expressed at low levels in healthy muscle but that its levels increased during hypertrophy or regeneration; in humans, VGLL3 was highly expressed in tissues from patients with various muscle diseases, such as in dystrophic muscle and alveolar rhabdomyosarcoma. Interaction proteomics revealed that VGLL3 bound TEAD1, TEAD3 and TEAD4 in myoblasts and/or myotubes. However, there was no interaction with proteins from major regulatory systems such as the Hippo kinase cascade, unlike what is found for the TEAD co-factors YAP (encoded by YAP1) and TAZ (encoded by WWTR1). Vgll3 overexpression reduced the activity of the Hippo negative-feedback loop, affecting expression of muscle-regulating genes including Myf5, Pitx2 and Pitx3, and genes encoding certain Wnts and IGFBPs. VGLL3 mainly repressed gene expression, regulating similar genes to those regulated by YAP and TAZ. siRNA-mediated Vgll3 knockdown suppressed myoblast proliferation, whereas Vgll3 overexpression strongly promoted myogenic differentiation. However, skeletal muscle was overtly normal in Vgll3-null mice, presumably due to feedback signalling and/or redundancy. This work identifies VGLL3 as a transcriptional co-factor operating with the Hippo signal transduction network to control myogenesis., Summary: VGLL3 interacts with TEAD transcription factors to direct expression of crucial muscle regulatory genes and contribute to the control of skeletal myogenesis.

Published
2019

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