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2. SIED-GISCOR recommendations for colonoscopy in screening programs: Part I – Diagnostic

Author

Parodi, Maria Caterina, Antonelli, Giulio, Galloro, Giuseppe, Radaelli, Franco, Manes, Giampiero, Manno, Mauro, Camellini, Lorenzo, Sereni, Giuliana, Caserta, Luigi, Arrigoni, Arrigo, Fasoli, Renato, Sassatelli, Romano, Pigò, Flavia, Iovino, Paola, Scimeca, Daniela, De Luca, Luca, Rizkala, Tommy, Tringali, Alberto, Campari, Cinzia, Capogreco, Antonio, Testoni, Sabrina Gloria Giulia, Bertani, Helga, Fantin, Alberto, Mitri, Roberto Di, Familiari, Pietro, Labardi, Maurizio, De Angelis, Claudio, Anghinoni, Emanuela, Rubeca, Tiziana, Cassoni, Paola, Zorzi, Manuel, Mussetto, Alessandro, Hassan, Cesare, and Senore, Carlo

Published
2024
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3. Predicting survival in patients with ‘non-high-risk’ acute variceal bleeding receiving β-blockers+ligation to prevent re-bleeding

Author

Balcar, Lorenz, Mandorfer, Mattias, Hernández-Gea, Virginia, Procopet, Bogdan, Meyer, Elias Laurin, Giráldez, Álvaro, Amitrano, Lucio, Villanueva, Candid, Thabut, Dominique, Samaniego, Luis Ibáñez, Silva-Junior, Gilberto, Martinez, Javier, Genescà, Joan, Bureau, Christophe, Trebicka, Jonel, Herrera, Elba Llop, Laleman, Wim, Palazón Azorín, José María, Alonso, Jose Castellote, Gluud, Lise Lotte, Ferreira, Carlos Noronha, Cañete, Nuria, Rodríguez, Manuel, Ferlitsch, Arnulf, Mundi, Jose Luis, Grønbæk, Henning, Hernandez Guerra, Manuel Nicolas, Sassatelli, Romano, Dell'Era, Alessandra, Senzolo, Marco, Abraldes, Juan Gonzalez, Romero-Gómez, Manuel, Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Primignani, Massimo, Krag, Aleksander, Nevens, Frederik, Calleja, Jose Luis, Jansen, Christian, Catalina, María Vega, Albillos, Agustín, Rudler, Marika, Tapias, Edilmar Alvarado, Guardascione, Maria Anna, Tantau, Marcel, Schwarzer, Rémy, Reiberger, Thomas, Laursen, Stig Borbjerg, Lopez-Gomez, Marta, Cachero, Alba, Ferrarese, Alberto, Ripoll, Cristina, La Mura, Vincenzo, Bosch, Jaime, and García-Pagán, Juan Carlos

Published
2024
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6. Effects of Attendance to an Organized Fecal Immunochemical Test Screening Program on the Risk of Colorectal Cancer: An Observational Cohort Study

Author

Finarelli, Alba Carola, Landi, Patrizia, Mezzetti, Francesca, Naldoni, Carlo, Sassoli de Bianchi, Priscilla, Ferretti, Stefano, Baldacchini, Flavia, Bucchi, Lauro, Giuliani, Orietta, Mancini, Silvia, Ravaioli, Alessandra, Zamagni, Federica, Vattiato, Rosa, Balducci, Chiara, Vitali, Benedetta, Falcini, Fabio, Aragona, Giovanni, Chiaranda, Giorgio, Penini, Francesca, Seghini, Pietro, Dalla Fiora, Cristian, Fattibene, Claudio, Maradini, Fabio, Orsi, Paolo, Benedetta Giannino, Giada Maria, Michiara, Maria, Giorgi Rossi, Paolo, Mangone, Lucia, Campari, Cinzia, Paterlini, Luisa, Sassatelli, Romano, Carrozzi, Giuliano, Gianfranco, De Girolamo, Esposito, Pasqualina, Rossi, Federica, Trande, Paolo, Viani, Simona, Cirilli, Claudia, Bazzani, Carmen, Bazzoli, Franco, Cennamo, Vincenzo, Giansante, Chiara, Gualandi, Giovanna, Manfredi, Marilena, Pasquini, Adriana, Caprara, Licia, De Lillo, Margherita, De Togni, Aldo, Palmonari, Caterina, Pasquali, Daniela, Zoli, Giorgio, Dal Re, Serena, Petrini, Chiara, Serafini, Monica, Triossi, Omero, Gallinucci, Mara, Imolesi, Claudia, Palazzi, Mauro, Canuti, Debora, Casale, Coralba, Giovanardi, Mauro, Trombetti, Daniele, Fabbri, Carlo, and Strocchi, Enrico

Published
2022
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7. Results of Compliant Participation in Five Rounds of Fecal Immunochemical Test Screening for Colorectal Cancer

Author

Ferretti, Stefano, Mezzetti, Francesca, Di Felice, Enza, Sassoli de Bianchi, Priscilla, Ventura, Chiara, Baldacchini, Flavia, Bucchi, Lauro, Colamartini, Americo, Giuliani, Orietta, Mancini, Silvia, Ravaioli, Alessandra, Vattiato, Rosa, Falcini, Fabio, Signorelli, Dario, Aragona, Giovanni, Pennini, Francesca, Chiaranda, Giorgio, Seghini, Pietro, Fiora, Cristian Dalla, Fattibene, Claudio, Michiara, Maria, Orsi, Paolo, Rossi, Paolo Giorgi, Mangone, Lucia, Campari, Cinzia, Sassatelli, Romano, Carrozzi, Giuliano, Rossi, Federica, Esposito, Pasqualina, Trande, Paolo, Viani, Simona, Ricciardiello, Luigi, Cennamo, Vincenzo, Gualandi, Giovanna, Caprara, Licia, De Lillo, Margherita, De Togni, Aldo, Palmonari, Caterina, Pasquali, Daniela, Zoli, Giorgio, Re, Serena Dal, Petrini, Chiara, Serafini, Monica, Triossi, Omero, Vitali, Benedetta, Gallinucci, Mara, Imolesi, Claudia, Palazzi, Mauro, Fabbri, Carlo, Canuti, Debora, Casale, Coralba, Giovanardi, Mauro, Trombetti, Daniele, and Giorgi Rossi, Paolo

Published
2021
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8. Effects of Early Placement of Transjugular Portosystemic Shunts in Patients With High-Risk Acute Variceal Bleeding: a Meta-analysis of Individual Patient Data

Author

Bureau, Christophe, Abraldes, Juan G., Nevens, Frederik, Caca, Karel, Laleman, Wim, Appenrodt, Beate, Luca, Angelo, Vinel, Jean Pierre, Mössner, Joachim, Di Pascoli, Marco, Zipprich, Alexander, Sauerbruch, Tilman, Martinez-Lagares, Francisco, Ruiz-del-Arbol, Luis, Sierra, Angel, Guevara, Clemencia, Jimenez, Elena, Marrero, Jose Miguel, Buceta, Enrique, Sanchez, Juan, Castellot, Ana, Penate, Monica, Cruz, Ana, Pena, Elena, Procopeț, Bogdan, Giráldez, Álvaro, Amitrano, Lucio, Villanueva, Candid, Ibañez-Samaniego, Luis, Silva-Junior, Gilberto, Martinez, Javier, Genescà, Joan, Trebicka, Jonel, Llop, Elba, Palazon, Jose Maria, Castellote, Jose, Rodrigues, Susana, Gluud, Lise L., Ferreira, Carlos Noronha, Barcelo, Rafael, Cañete, Nuria, Rodríguez, Manuel, Ferlitsch, Arnulf, Mundi, Jose Luis, Gronbaek, Henning, Hernández-Guerra, Manuel, Sassatelli, Romano, Dell’Era, Alessandra, Senzolo, Marco, Romero-Gómez, Manuel, Casas, Meritxell, Masnou, Helena, Primignani, Massimo, Krag, Aleksander, Calleja, Jose Luis, Jansen, Christian, Robic, Marie Angèle, Conejo, Irene, Catalina, Maria-Vega, Albillos, Agustin, Alvarado, Edilmar, Guardascione, Maria Anna, Tanțău, Marcel, Zuo, Luo, Zhu, Xuan, Zhao, Jianbo, Xue, Hui, Jiang, Zaibo, Zhuge, Yuzheng, Zhang, Chunqing, Sun, Junhui, Ding, Pengxu, Ren, Weixin, Li, Yingchun, Zhang, Kewei, Zhang, Wenguang, He, Chuangye, Zhong, Jiawei, Peng, Qifeng, Ma, Fuquan, Luo, Junyang, Zhang, Ming, Wang, Guangchuan, Sun, Minhuang, Dong, Junjiao, Bai, Wei, Guo, Wengang, Wang, Qiuhe, Yuan, Xulong, Wang, Zhengyu, Yu, Tianlei, Luo, Bohan, Li, Xiaomei, Yuan, Jie, Han, Na, Zhu, Ying, Niu, Jing, Li, Kai, Yin, Zhanxin, Nie, Yongzhan, Fischer, Petra, Horia Ștefănescu, Pop, Andreea, Laursen, Stig B., Turon, Fanny, Baiges, Anna, Ferrusquía-Acosta, José, Magaz, Marta, Cerda, Eira, Tellez, Luis, Allegretti, Giulia, Macedo, Guilherme, Haldrup, David, Santos, Patricia, Moura, Miguel, Reis, Daniela, Meireles, Liliane, Sousa, Patricia, Alexandrino, Paula, Navascues, Carmen, Augustin, Salvador, La Mura, Vincenzo, Bañares, Rafael, Diaz, Raquel, Gómez, Marta López, Ripoll, Cristina, Nicoară-Farcău, Oana, Han, Guohong, Rudler, Marika, Angrisani, Debora, Monescillo, Alberto, Torres, Ferran, Casanovas, Georgina, Bosch, Jaime, Lv, Yong, Thabut, Dominique, Fan, Daiming, Hernández-Gea, Virginia, and García-Pagán, Juan Carlos

Published
2021
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10. Epidemiology, clinical features and diagnostic work-up of cystic neoplasms of the pancreas: Interim analysis of the prospective PANCY survey

Author

Pezzilli, Raffaele, Buscarini, Elisabetta, Pollini, Tommaso, Bonamini, Deborah, Marchegiani, Giovanni, Crippa, Stefano, Belfiori, Giulio, Sperti, Cosimo, Moletta, Lucia, Pozza, Gioia, De Nucci, Germana, Manes, Giampiero, Mandelli, Enzo D., Casadei, Riccardo, Ricci, Claudio, Alicante, Saverio, Vattiato, Claudia, Carrara, Silvia, Di Leo, Milena, Fabbri, Carlo, Giovanelli, Silvia, Barresi, Luca, Tacelli, Matteo, Mirante, Vincenzo G., Conigliaro, Rita, Antonini, Filippo, Macarri, Giampiero, Frulloni, Luca, De Marchi, Giulia, Sassatelli, Romano, Cecinato, Paolo, Del Vecchio Blanco, Giovanna, Galli, Andrea, Pezzullo, Angelo, Fantin, Alberto, Graffeo, Massimo, Frego, Mauro, Stillittano, Domenico, Monica, Fabio, Germanà, Bastianello, Capurso, Gabriele, Quartini, Mariano, Veneroni, Luigi, Cannizzaro, Renato, and Falconi, Massimo

Published
2020
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12. Urgent ERCP performed with single-use duodenoscope (SUD) in patients with moderate-to-severe cholangitis – a single-center prospective study.

Author

Masciangelo, Graziella, additional, Cecinato, Paolo, additional, Bacchilega, Igor, additional, Masetti, Michele, additional, Ferrari, Rodolfo, additional, Zagari, Rocco Maurizio, additional, Napoleon, Bertrand, additional, Sassatelli, Romano, additional, Fusaroli, Pietro, additional, and Lisotti, Andrea, additional

Published
2023
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13. Outcomes of a 3-Year Prospective Surveillance in Individuals at High Risk of Pancreatic Cancer

Author

Paiella, Salvatore, primary, Capurso, Gabriele, additional, Carrara, Silvia, additional, Secchettin, Erica, additional, Casciani, Fabio, additional, Frigerio, Isabella, additional, Zerbi, Alessandro, additional, Archibugi, Livia, additional, Bonifacio, Cristiana, additional, Malleo, Giuseppe, additional, Cavestro, Giulia Martina, additional, Barile, Monica, additional, Larghi, Alberto, additional, Assisi, Daniela, additional, Fantin, Alberto, additional, Milanetto, Anna Caterina, additional, Fabbri, Carlo, additional, Casadei, Riccardo, additional, Donato, Giulio, additional, Sassatelli, Romano, additional, De Marchi, Giulia, additional, Di Matteo, Francesco Maria, additional, Arcangeli, Valentina, additional, Panzuto, Francesco, additional, Puzzono, Marta, additional, Dal Buono, Arianna, additional, Pezzilli, Raffaele, additional, Salvia, Roberto, additional, Rizzatti, Gianenrico, additional, Casadio, Marco, additional, Franco, Monica, additional, Butturini, Giovanni, additional, Pasquali, Claudio, additional, Coluccio, Chiara, additional, Ricci, Claudio, additional, Cicchese, Noemi, additional, Sereni, Giuliana, additional, de Pretis, Nicolò, additional, Stigliano, Serena, additional, Rudnas, Britt, additional, Marasco, Matteo, additional, Lionetto, Gabriella, additional, Arcidiacono, Paolo Giorgio, additional, Terrin, Maria, additional, Crovetto, Anna, additional, Mannucci, Alessandro, additional, Laghi, Luigi, additional, Bassi, Claudio, additional, and Falconi, Massimo, additional

Published
2023
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14. Efficacy and safety of plastic, covered and uncovered self-expandable metal stents in the treatment of malignant biliary obstructions

Author

Binda, Cecilia, primary, Vannella, Giuseppe, additional, Cucchetti, Alessandro, additional, Di Mitri, Roberto, additional, Crinò, Stefano Francesco, additional, Sassatelli, Romano, additional, Piras, Enrico, additional, Mussetto, Alessandro, additional, Fugazza, Alessandro, additional, Coluccio, Chiara, additional, Fuccio, Lorenzo, additional, Cugia, Luigi, additional, Di Marco, Marco, additional, Di Matteo, Francesco Maria, additional, Cennamo, Vincenzo, additional, Spada, Cristiano, additional, Manno, Mauro, additional, Amato, Arnaldo, additional, Fantin, Alberto, additional, Mutignani, Massimiliano, additional, Aragona, Giovanni, additional, De Angelis, Claudio, additional, Marocchi, Gianmarco, additional, Merighi, Alberto, additional, Macchiarelli, Raffaele, additional, Arcidiacono, Paolo Giorgio, additional, Amata, Michele, additional, Gabbrielli, Armando, additional, Mirante, Vincenzo Giorgio, additional, Anna, Giuseppe Dell', additional, Palmeri, Enrico, additional, Trebbi, Margherita, additional, Colombo, Matteo, additional, La Marca, Marina, additional, Fiori, Salvatore, additional, De Padova, Angelo, additional, Bassi, Marco, additional, Olivari, Nicola, additional, Soriani, Paola, additional, Tamanini, Giacomo, additional, Grillo, Sabina, additional, Forti, Edoardo, additional, Sacco, Marco, additional, Andreozzi, Marta, additional, Repici, Alessandro, additional, Fabbri, Carlo, additional, Tarantino, Ilaria, additional, Anderloni, Andrea, additional, and Maria Rizzo, Giacomo Emanuele, additional

Published
2023
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15. Endoscopic papillectomy: a multicentre, retrospective, nationwide study after the standardisation of the technique

Author

Binda, Cecilia, primary, Fabbri, Stefano, additional, Cucchetti, Alessandro, additional, Mutignani, Massimiliano, additional, Tringali, Andrea, additional, Di Mitri, Roberto, additional, Fugazza, Alessandro, additional, Sassatelli, Romano, additional, Gabbrielli, Armando, additional, Arcidiacono, Paolo Giorgio, additional, Di Matteo, Francesco Maria, additional, Coluccio, Chiara, additional, Di Marco, Marco, additional, Spada, Cristiano, additional, Fantin, Alberto, additional, De Angelis, Claudio, additional, Macchiarelli, Raffaele, additional, Perri, Francesco, additional, Manno, Mauro, additional, Cugia, Luigi, additional, Mussetto, Alessandro, additional, Dioscoridi, Lorenzo, additional, Schepis, Tommaso, additional, Scimeca, Daniela, additional, Da Rio, Leonardo, additional, Cecinato, Paolo, additional, Crinò, Stefano Francesco, additional, Repici, Alessandro, additional, Tarantino, Ilaria, additional, Anderloni, Andrea, additional, and Fabbri, Carlo, additional

Published
2023
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16. Outcomes of a 3-Year Prospective Surveillance in Individuals at High Risk of Pancreatic Cancer.

Author

Paiella, Salvatore, Capurso, Gabriele, Carrara, Silvia, Secchettin, Erica, Casciani, Fabio, Frigerio, Isabella, Zerbi, Alessandro, Archibugi, Livia, Bonifacio, Cristiana, Malleo, Giuseppe, Martina Cavestro, Giulia, Barile, Monica, Larghi, Alberto, Assisi, Daniela, Fantin, Alberto, Caterina Milanetto, Anna, Fabbri, Carlo, Casadei, Riccardo, Donato, Giulio, and Sassatelli, Romano

Published
2024
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17. Predicting survival in patients with ‘non-high-risk’ acute variceal bleeding receiving β-blockers+ligation to prevent re-bleeding

Author

Balcar, Lorenz, primary, Mandorfer, Mattias, additional, Hernández-Gea, Virginia, additional, Procopet, Bogdan, additional, Meyer, Elias Laurin, additional, Giráldez, Álvaro, additional, Amitrano, Lucio, additional, Villanueva, Candid, additional, Thabut, Dominique, additional, Samaniego, Luis Ibáñez, additional, Silva-Junior, Gilberto, additional, Martinez, Javier, additional, Genescà, Joan, additional, Bureau, Christophe, additional, Trebicka, Jonel, additional, Llop Herrera, Elba, additional, Laleman, Wim, additional, Palazón Azorín, José María, additional, Castellote Alonso, Jose, additional, Gluud, Lise Lotte, additional, Noronha Ferreira, Carlos, additional, Cañete, Nuria, additional, Rodríguez, Manuel, additional, Ferlitsch, Arnulf, additional, Mundi, Jose Luis, additional, Grønbæk, Henning, additional, Hernandez Guerra, Manuel Nicolas, additional, Sassatelli, Romano, additional, Dell'Era, Alessandra, additional, Senzolo, Marco, additional, Abraldes, Juan Gonzalez, additional, Romero-Gómez, Manuel, additional, Zipprich, Alexander, additional, Casas, Meritxell, additional, Masnou, Helena, additional, Primignani, Massimo, additional, Krag, Aleksander, additional, Nevens, Frederik, additional, Calleja, Jose Luis, additional, Jansen, Christian, additional, Vega Catalina, María, additional, Albillos, Agustín, additional, Rudler, Marika, additional, Tapias, Edilmar Alvarado, additional, Guardascione, Maria Anna, additional, Tantau, Marcel, additional, Schwarzer, Rémy, additional, Reiberger, Thomas, additional, Laursen, Stig Borbjerg, additional, Lopez-Gomez, Marta, additional, Cachero, Alba, additional, Ferrarese, Alberto, additional, Ripoll, Cristina, additional, La Mura, Vincenzo, additional, Bosch, Jaime, additional, and García-Pagán, Juan Carlos, additional

Published
2023
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18. Effectiveness of double-balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography (DBE-ERCP): A multicenter real-world study

Author

Farina, Elisa, primary, Cantù, Paolo, additional, Cavallaro, Flaminia, additional, Iori, Veronica, additional, Rosa-Rizzotto, Erik, additional, Cavina, Maurizio, additional, Tontini, Gian Eugenio, additional, Nandi, Nicoletta, additional, Scaramella, Lucia, additional, Sassatelli, Romano, additional, Penagini, Roberto, additional, Vecchi, Maurizio, additional, and Elli, Luca, additional

Published
2023
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19. Hepatic encephalopathy is not a contraindication to pre-emptive TIPS in high-risk patients with cirrhosis with variceal bleeding

Author

Rudler, Marika, Hernández-Gea, Virginia, Procopet, Bogdan Dumitru, Giráldez, Alvaro, Amitrano, Lucio, Villanueva, Càndid, Ibañez, Luis, Silva-Junior, Gilberto, Genesca, Joan, Bureau, Christophe, Trebicka, Jonel, Bañares, Rafael, Krag, Aleksander, Llop, Elba, Laleman, Wim, Palazon, Jose Maria, Castellote, Jose, Rodrigues, Susana, Gluud, Lise Lotte, Noronha Ferreira, Carlos, Canete, Nouria, Rodríguez, Manuel, Ferlitsch, Arnulf, Mundi, Jose Luis, Gronbaek, Henning, Hernandez-Guerra, Manuel, Sassatelli, Romano, Dell'Era, Alessandra, Senzolo, Marco, Abraldes, Juan G, Romero-Gómez, Manuel, Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Larrue, Hélène, Primignani, Massimo, Nevens, Frederik, Calleja, Jose Luis, Schwarzer, Remy, Jansen, Christian, Robic, Marie Angèle, Conejo, Irene, Gonzalez, Javier Martínez, Catalina, Maria Vega, Albillos, Agustín, Alvarado, Edilmar, Guardascione, Maria Anna, Mallet, Maxime, Tripon, Simona, Casanovas, Georgina, Bosch, Jaume, Garcia-Pagan, Juan-Carlos, Thabut, Dominique, Rudler, Marika, Hernández-Gea, Virginia, Procopet, Bogdan Dumitru, Giráldez, Alvaro, Amitrano, Lucio, Villanueva, Càndid, Ibañez, Luis, Silva-Junior, Gilberto, Genesca, Joan, Bureau, Christophe, Trebicka, Jonel, Bañares, Rafael, Krag, Aleksander, Llop, Elba, Laleman, Wim, Palazon, Jose Maria, Castellote, Jose, Rodrigues, Susana, Gluud, Lise Lotte, Noronha Ferreira, Carlos, Canete, Nouria, Rodríguez, Manuel, Ferlitsch, Arnulf, Mundi, Jose Luis, Gronbaek, Henning, Hernandez-Guerra, Manuel, Sassatelli, Romano, Dell'Era, Alessandra, Senzolo, Marco, Abraldes, Juan G, Romero-Gómez, Manuel, Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Larrue, Hélène, Primignani, Massimo, Nevens, Frederik, Calleja, Jose Luis, Schwarzer, Remy, Jansen, Christian, Robic, Marie Angèle, Conejo, Irene, Gonzalez, Javier Martínez, Catalina, Maria Vega, Albillos, Agustín, Alvarado, Edilmar, Guardascione, Maria Anna, Mallet, Maxime, Tripon, Simona, Casanovas, Georgina, Bosch, Jaume, Garcia-Pagan, Juan-Carlos, and Thabut, Dominique

Abstract

Background: A pre-emptive transjugular intrahepatic portosystemic shunt (pTIPS) reduces mortality in high-risk patients with cirrhosis (Child-Pugh C/B+active bleeding) with acute variceal bleeding (AVB). Real-life studies point out that <15% of patients eligible for pTIPS ultimately undergo transjugular intrahepatic portosystemic shunt (TIPS) due to concerns about hepatic encephalopathy (HE). The outcome of patients undergoing pTIPS with HE is unknown. We aimed to (1) assess the prevalence of HE in patients with AVB; (2) evaluate the outcome of patients presenting HE at admission after pTIPS; and (3) determine if HE at admission is a risk factor for death and post-TIPS HE. Patients and methods: This is an observational study including 2138 patients from 34 centres between October 2011 and May 2015. Placement of pTIPS was based on individual centre policy. Patients were followed up to 1 year, death or liver transplantation. Results: 671 of 2138 patients were considered at high risk, 66 received pTIPS and 605 endoscopic+drug treatment. At admission, HE was significantly more frequent in high-risk than in low-risk patients (39.2% vs 10.6%, p<0.001). In high-risk patients with HE at admission, pTIPS was associated with a lower 1-year mortality than endoscopic+drug (HR 0.374, 95% CI 0.166 to 0.845, p=0.0181). The incidence of HE was not different between patients treated with pTIPS and endoscopic+drug (38.2% vs 38.7%, p=0.9721), even in patients with HE at admission (56.4% vs 58.7%, p=0.4594). Age >56, shock, Model for End-Stage Liver Disease score >15, endoscopic+drug treatment and HE at admission were independent factors of death in high-risk patients. Conclusion: pTIPS is associated with better survival than endoscopic treatment in high-risk patients with cirrhosis with variceal bleeding displaying HE at admission.

Published
2023

20. Alcohol-related liver disease phenotype impacts survival after an acute variceal bleeding episode

Author

Instituto de Salud Carlos III, Villagrasa, Ares, Hernández-Gea, Virginia, Bataller, Ramón, Giráldez, Álvaro, Procopet, Bogdan, Amitrano, Lucio, Villanueva, Candid, Thabut, Dominique, Ibáñez-Samaniego, Luis, Albillos, Agustin, Bureau, Christophe, Trebicka, Jonel, Llop, Elba, Laleman, Wim, Palazón, Jose María, Castellote, José, Rodrigues, Susana, Gluud, Lise L., Ferreira, Carlos N., Cañete, Nuria, Rodríguez, Manuel, Ferlitsch, Arnulf, Mundi, José Luis, Gronbaek, Henning, Hernández-Guerra, Manuel, Sassatelli, Romano, Alessandra Dell'Era, Senzolo, Marco, Abraldes, Juan G., Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Primignani, Massimo, Krag, Aleksander, Silva-Junior, Gilberto, Romero-Gómez, Manuel, Tantau, Marcel, Guardascione, Maria Anna, Alvarado, Edilmar, Rudler, Marika, Bañares, Rafael, Martínez, Javier, Robic, Marie Angèle, Jansen, Christian, Calleja, José Luis, Nevens, Frederik, Bosch, Jaime, Ventura-Cots, Meritxell, García-Pagán, Juan Carlos, Genescà, Joan, for the International Variceal Bleeding Observational Study Group; Baveno Cooperation, Instituto de Salud Carlos III, Villagrasa, Ares, Hernández-Gea, Virginia, Bataller, Ramón, Giráldez, Álvaro, Procopet, Bogdan, Amitrano, Lucio, Villanueva, Candid, Thabut, Dominique, Ibáñez-Samaniego, Luis, Albillos, Agustin, Bureau, Christophe, Trebicka, Jonel, Llop, Elba, Laleman, Wim, Palazón, Jose María, Castellote, José, Rodrigues, Susana, Gluud, Lise L., Ferreira, Carlos N., Cañete, Nuria, Rodríguez, Manuel, Ferlitsch, Arnulf, Mundi, José Luis, Gronbaek, Henning, Hernández-Guerra, Manuel, Sassatelli, Romano, Alessandra Dell'Era, Senzolo, Marco, Abraldes, Juan G., Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Primignani, Massimo, Krag, Aleksander, Silva-Junior, Gilberto, Romero-Gómez, Manuel, Tantau, Marcel, Guardascione, Maria Anna, Alvarado, Edilmar, Rudler, Marika, Bañares, Rafael, Martínez, Javier, Robic, Marie Angèle, Jansen, Christian, Calleja, José Luis, Nevens, Frederik, Bosch, Jaime, Ventura-Cots, Meritxell, García-Pagán, Juan Carlos, Genescà, Joan, and for the International Variceal Bleeding Observational Study Group; Baveno Cooperation

Abstract

[Background & Aims] Alcohol-related hepatitis (AH) encompasses a high mortality. AH might be a concomitant event in patients with acute variceal bleeding (AVB). The current study aimed to assess the prevalence of AH in patients with AVB and to compare the clinical outcomes of AH patients to other alcohol-related liver disease (ALD) phenotypes and viral cirrhosis., [Methods] Multicentre, observational study including 916 patients with AVB falling under the next categories: AH (n = 99), ALD cirrhosis actively drinking (d-ALD) (n = 285), ALD cirrhosis abstinent from alcohol (a-ALD) (n = 227) and viral cirrhosis (n = 305). We used a Cox proportional hazards model to calculate adjusted hazard ratio (HR) of death adjusted by MELD., [Results] The prevalence of AH was 16% considering only ALD patients. AH patients exhibited more complications. Forty-two days transplant-free survival was worse among AH, but statistical differences were only observed between AH and d-ALD groups (84 vs. 93%; p = 0.005), when adjusted by MELD no differences were observed between AH and the other groups. At one-year, survival of AH patients (72.7%) was similar to the other groups; when adjusted by MELD mortality HR was better in AH compared to a-ALD (0.48; 0.29–0.8, p = 0.004). Finally, active drinkers who remained abstinent presented better survival, independently of having AH., [Conclusions] Contrary to expected, AH patients with AVB present no worse one-year survival than other patients with different alcohol-related phenotypes or viral cirrhosis. Abstinence influences long-term survival and could explain these counterintuitive results.

Published
2023

21. Alcohol-related liver disease phenotype impacts survival after an acute variceal bleeding episode

Author

Villagrasa, Ares, Hernandez-Gea, Virginia, Bataller, Ramon, Giraldez, Alvaro, Procopet, Bogdan, Amitrano, Lucio, Villanueva, Candid, Thabut, Dominique, Ibanez-Samaniego, Luis, Albillos, Agustin, Bureau, Christophe, Trebicka, Jonel, Llop, Elba, Laleman, Wim, Palazon, J. M., Castellote, Jose, Rodrigues, Susana L., Gluud, Lise N., Ferreira, Carlos, Canete, Nuria, Rodriguez, Manuel, Ferlitsch, Arnulf L., Mundi, Jose, Gronbaek, Henning, Hernandez-Guerra, Manuel, Sassatelli, Romano, Dell'Era, Alessandra, Senzolo, Marco G., Abraldes, Juan, Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Primignani, Massimo, Krag, Aleksander, Silva-Junior, Gilberto, Romero-Gomez, Manuel, Tantau, Marcel A., Guardascione, Maria, Alvarado, Edilmar, Rudler, Marika, Banares, Rafael, Martinez, Javier A., Robic, Marie, Jansen, Christian L., Calleja, Jose, Nevens, Frederik, Gluud, Lise Lotte, Bosch, Jaime, Ventura-Cots, Meritxell C., Garcia-Pagan, Juan, Genesca, Joan, Villagrasa, Ares, Hernandez-Gea, Virginia, Bataller, Ramon, Giraldez, Alvaro, Procopet, Bogdan, Amitrano, Lucio, Villanueva, Candid, Thabut, Dominique, Ibanez-Samaniego, Luis, Albillos, Agustin, Bureau, Christophe, Trebicka, Jonel, Llop, Elba, Laleman, Wim, Palazon, J. M., Castellote, Jose, Rodrigues, Susana L., Gluud, Lise N., Ferreira, Carlos, Canete, Nuria, Rodriguez, Manuel, Ferlitsch, Arnulf L., Mundi, Jose, Gronbaek, Henning, Hernandez-Guerra, Manuel, Sassatelli, Romano, Dell'Era, Alessandra, Senzolo, Marco G., Abraldes, Juan, Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Primignani, Massimo, Krag, Aleksander, Silva-Junior, Gilberto, Romero-Gomez, Manuel, Tantau, Marcel A., Guardascione, Maria, Alvarado, Edilmar, Rudler, Marika, Banares, Rafael, Martinez, Javier A., Robic, Marie, Jansen, Christian L., Calleja, Jose, Nevens, Frederik, Gluud, Lise Lotte, Bosch, Jaime, Ventura-Cots, Meritxell C., Garcia-Pagan, Juan, and Genesca, Joan

Abstract

Background & AimsAlcohol-related hepatitis (AH) encompasses a high mortality. AH might be a concomitant event in patients with acute variceal bleeding (AVB). The current study aimed to assess the prevalence of AH in patients with AVB and to compare the clinical outcomes of AH patients to other alcohol-related liver disease (ALD) phenotypes and viral cirrhosis. MethodsMulticentre, observational study including 916 patients with AVB falling under the next categories: AH (n = 99), ALD cirrhosis actively drinking (d-ALD) (n = 285), ALD cirrhosis abstinent from alcohol (a-ALD) (n = 227) and viral cirrhosis (n = 305). We used a Cox proportional hazards model to calculate adjusted hazard ratio (HR) of death adjusted by MELD. ResultsThe prevalence of AH was 16% considering only ALD patients. AH patients exhibited more complications. Forty-two days transplant-free survival was worse among AH, but statistical differences were only observed between AH and d-ALD groups (84 vs. 93%; p = 0.005), when adjusted by MELD no differences were observed between AH and the other groups. At one-year, survival of AH patients (72.7%) was similar to the other groups; when adjusted by MELD mortality HR was better in AH compared to a-ALD (0.48; 0.29-0.8, p = 0.004). Finally, active drinkers who remained abstinent presented better survival, independently of having AH. ConclusionsContrary to expected, AH patients with AVB present no worse one-year survival than other patients with different alcohol-related phenotypes or viral cirrhosis. Abstinence influences long-term survival and could explain these counterintuitive results.

Published
2023

26. Effects of Attendance to an Organized Fecal Immunochemical Test Screening Program on the Risk of Colorectal Cancer: An Observational Cohort Study

Author

Baldacchini, Flavia, primary, Bucchi, Lauro, additional, Giuliani, Orietta, additional, Mancini, Silvia, additional, Ravaioli, Alessandra, additional, Vattiato, Rosa, additional, Zamagni, Federica, additional, Giorgi Rossi, Paolo, additional, Mangone, Lucia, additional, Campari, Cinzia, additional, Sassatelli, Romano, additional, Trande, Paolo, additional, Esposito, Pasqualina, additional, Rossi, Federica, additional, Carrozzi, Giuliano, additional, Triossi, Omero, additional, Fabbri, Carlo, additional, Strocchi, Enrico, additional, Giovanardi, Mauro, additional, Canuti, Debora, additional, Sassoli de Bianchi, Priscilla, additional, Ferretti, Stefano, additional, Falcini, Fabio, additional, Finarelli, Alba Carola, additional, Landi, Patrizia, additional, Mezzetti, Francesca, additional, Naldoni, Carlo, additional, Baldacchini, Flavia, additional, Balducci, Chiara, additional, Vitali, Benedetta, additional, Aragona, Giovanni, additional, Chiaranda, Giorgio, additional, Penini, Francesca, additional, Seghini, Pietro, additional, Dalla Fiora, Cristian, additional, Fattibene, Claudio, additional, Maradini, Fabio, additional, Orsi, Paolo, additional, Benedetta Giannino, Giada Maria, additional, Michiara, Maria, additional, Paterlini, Luisa, additional, Gianfranco, De Girolamo, additional, Viani, Simona, additional, Cirilli, Claudia, additional, Bazzani, Carmen, additional, Bazzoli, Franco, additional, Cennamo, Vincenzo, additional, Giansante, Chiara, additional, Gualandi, Giovanna, additional, Manfredi, Marilena, additional, Pasquini, Adriana, additional, Caprara, Licia, additional, De Lillo, Margherita, additional, De Togni, Aldo, additional, Palmonari, Caterina, additional, Pasquali, Daniela, additional, Zoli, Giorgio, additional, Dal Re, Serena, additional, Petrini, Chiara, additional, Serafini, Monica, additional, Gallinucci, Mara, additional, Imolesi, Claudia, additional, Palazzi, Mauro, additional, Casale, Coralba, additional, and Trombetti, Daniele, additional

Published
2022
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27. Hepatic encephalopathy is not a contraindication to pre-emptive TIPS in high-risk patients with cirrhosis with variceal bleeding

Author

Rudler, Marika, primary, Hernández-Gea, Virginia, additional, Procopet, Bogdan Dumitru, additional, Giráldez, Alvaro, additional, Amitrano, Lucio, additional, Villanueva, Càndid, additional, Ibañez, Luis, additional, Silva-Junior, Gilberto, additional, Genesca, Joan, additional, Bureau, Christophe, additional, Trebicka, Jonel, additional, Bañares, Rafael, additional, Krag, Aleksander, additional, Llop, Elba, additional, Laleman, Wim, additional, Palazon, Jose Maria, additional, Castellote, Jose, additional, Rodrigues, Susana, additional, Gluud, Lise Lotte, additional, Noronha Ferreira, Carlos, additional, Canete, Nouria, additional, Rodríguez, Manuel, additional, Ferlitsch, Arnulf, additional, Mundi, Jose Luis, additional, Gronbaek, Henning, additional, Hernandez-Guerra, Manuel, additional, Sassatelli, Romano, additional, Dell’era, Alessandra, additional, Senzolo, Marco, additional, Abraldes, Juan G, additional, Romero-Gómez, Manuel, additional, Zipprich, Alexander, additional, Casas, Meritxell, additional, Masnou, Helena, additional, Larrue, Hélène, additional, Primignani, Massimo, additional, Nevens, Frederik, additional, Calleja, Jose Luis, additional, Schwarzer, Remy, additional, Jansen, Christian, additional, Robic, Marie-Angèle, additional, Conejo, Irene, additional, Martínez Gonzalez, Javier, additional, Catalina, Maria Vega, additional, Albillos, Agustín, additional, Alvarado, Edilmar, additional, Guardascione, Maria Anna, additional, Mallet, Maxime, additional, Tripon, Simona, additional, Casanovas, Georgina, additional, Bosch, Jaume, additional, Garcia-Pagan, Juan-Carlos, additional, and Thabut, Dominique, additional

Published
2022
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30. Full-spectrum (FUSE) versus standard forward-viewing colonoscopy in an organised colorectal cancer screening programme

Author

Hassan, Cesare, Senore, Carlo, Radaelli, Franco, De Pretis, Giovanni, Sassatelli, Romano, Arrigoni, Arrigo, Manes, Gianpiero, Amato, Arnaldo, Anderloni, Andrea, Armelao, Franco, Mondardini, Alessandra, Spada, Cristiano, Omazzi, Barbara, Cavina, Maurizio, Miori, Gianni, Campanale, Chiara, Sereni, Giuliana, Segnan, Nereo, and Repici, Alessandro

Published
2017
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31. Management of colovesical fistula: a systematic review

Author

ZIZZO, Maurizio, primary, TUMIATI, David, additional, BASSI, Maria C., additional, ZANELLI, Magda, additional, SANGUEDOLCE, Francesca, additional, PORPIGLIA, Francesco, additional, FIORI, Cristian, additional, CAMPOBASSO, Davide, additional, CASTRO RUIZ, Carolina, additional, BERGAMASCHI, Franco A., additional, MAESTRONI, Umberto V., additional, CARRIERI, Giuseppe, additional, CORMIO, Luigi, additional, BIOLCHINI, Federico, additional, PALICELLI, Andrea, additional, SORIANO, Alessandra, additional, SASSATELLI, Romano, additional, ASCANI, Stefano, additional, ANNESSI, Valerio, additional, and GIUNTA, Alessandro, additional

Published
2022
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32. Worldwide trends in population-based survival for children, adolescents, and young adults diagnosed with leukaemia, by subtype, during 2000–14 (CONCORD-3): analysis of individual data from 258 cancer registries in 61 countries

Author

Ssenyonga, Naomi, primary, Stiller, Charles, additional, Nakata, Kayo, additional, Shalkow, Jaime, additional, Redmond, Shelagh, additional, Bulliard, Jean-Luc, additional, Girardi, Fabio, additional, Fowler, Christine, additional, Marcos-Gragera, Rafael, additional, Bonaventure, Audrey, additional, Saint-Jacques, Nathalie, additional, Minicozzi, Pamela, additional, De, Prithwish, additional, Rodríguez-Barranco, Miguel, additional, Larønningen, Siri, additional, Di Carlo, Veronica, additional, Mägi, Margit, additional, Valkov, Mikhail, additional, Seppä, Karri, additional, Wyn Huws, Dyfed, additional, Coleman, Michel P, additional, Allemani, Claudia, additional, Bouzbid, Sabiha, additional, Hamdi-Chérif, Mokhtar, additional, Kara, Lamia, additional, Meguenni, Kaouel, additional, Regagba, Derbali, additional, Bayo, Sine, additional, Cheick Bougadari, Traore, additional, Manraj, Shyam Shunker, additional, Bendahhou, Karima, additional, Ladipo, Akinade, additional, Ogunbiyi, Olufemi, additional, Somdyala, Nontuthuzelo, additional, Chaplin, María Agustina, additional, Moreno, Florencia, additional, Calabrano, Gladis, additional, Espinola, Silvia, additional, Carballo Quintero, Beatriz, additional, Fita, Rosalba, additional, Laspada, Walter, additional, Ibañez, Susana, additional, Lima, Carlos, additional, Mafra Da Costa, Allini, additional, De Souza, Paulo César, additional, Chaves, Juliana, additional, Laporte, Cyntia, additional, Curado, Maria Paula, additional, de Oliveira, Jose Carlos, additional, Veneziano, Claudia, additional, Veneziano, Donaldo, additional, Almeida, Ana Beatriz, additional, Latorre, Maria, additional, Azevedo e Silva, Gulnar, additional, Rebelo, Marise, additional, Santos, Marceli, additional, Galaz, Juan, additional, Aparicio Aravena, Mackarena, additional, Sanhueza Monsalve, Jocelyn, additional, Herrmann, Denise, additional, Vargas, Solange, additional, Herrera, Victor, additional, Uribe, Claudia, additional, Bravo, Luis Eduardo, additional, Garcia, Luz Stella, additional, Arias-Ortiz, Nelson, additional, Morantes, Daniela, additional, Jurado, Daniel, additional, Yépez Chamorro, María, additional, Delgado, Sandra, additional, Ramirez, Melissa, additional, Galán Alvarez, Yaima, additional, Torres, Priscila, additional, Martínez-Reyes, Fray, additional, Jaramillo, Leyda, additional, Quinto, Rina, additional, Castillo, Jhoanna, additional, Mendoza, Mariela, additional, Cueva, Patricia, additional, Yépez, José, additional, Bhakkan, Bernard, additional, Deloumeaux, Jacqueline, additional, Joachim, Clarisse, additional, Macni, Jonathan, additional, Carrillo, Rodolfo, additional, Shalkow Klincovstein, Jaime, additional, Rivera Gomez, Rebeca, additional, Perez, Patricia, additional, Poquioma, Ebert, additional, Tortolero-Luna, Guillermo, additional, Zavala, Diego, additional, Alonso, Rafael, additional, Barrios, Enrique, additional, Eckstrand, Angela, additional, Nikiforuk, Cindy, additional, Woods, Ryan, additional, Noonan, Gail, additional, Turner, Donna, additional, Kumar, Eshwar, additional, Zhang, Bin, additional, Dowden, Jeff, additional, Doyle, Gregory, additional, Walsh, Gordon, additional, Anam, Aniq, additional, McClure, Carol, additional, Vriends, Kim, additional, Bertrand, Christine, additional, Ramanakumar, Agnihotram, additional, Kozie, Serena, additional, Stuart-Panko, Heather, additional, Freeman, Tara, additional, George, Justin, additional, Avila, Rosa, additional, O'Brien, David, additional, Holt, Abby, additional, Almon, Lyn, additional, Ward, Kevin, additional, Kwong, Sandy, additional, Morris, Cyllene, additional, Rycroft, Randi, additional, Mueller, Lloyd, additional, Phillips, Cathryn, additional, Brown, Heather, additional, Cromartie, Betsy, additional, Ruterbusch, Julie, additional, Schwartz, Ann, additional, Levin, Gary, additional, Wohler, Brad, additional, Bayakly, Rana, additional, Gomez, Scarlett, additional, McKinley, Meg, additional, Cress, Rosemary, additional, Davis, Joni, additional, Hernandez, Brenda, additional, Johnson, Christopher, additional, Morawski, Bozena, additional, Ruppert, Laura, additional, Bentler, Suzanne, additional, Charlton, Mary, additional, Huang, Bin, additional, Tucker, Thomas, additional, Deapen, Dennis, additional, Liu, Lihua, additional, Hsieh, Mei-Chin, additional, Wu, Xiao-Cheng, additional, Schwenn, Molly, additional, Stern, Kimberly, additional, Gershman, Susan, additional, Knowlton, Richard, additional, Alverson, Georgetta, additional, Weaver, Tamara, additional, Desai, Jay, additional, Rogers, Deirdre, additional, Jackson-Thompson, Jeanette, additional, Lemons, Debbi, additional, Zimmerman, Heather, additional, Hood, Michelle, additional, Roberts-Johnson, Jenifer, additional, Hammond, Whitney, additional, Rees, Judith, additional, Pawlish, Karen, additional, Stroup, Antoinette, additional, Key, Charles, additional, Wiggins, Charles, additional, Kahn, Amy, additional, Schymura, Maria, additional, Radhakrishnan, Soundarya, additional, Rao, Chandrika, additional, Giljahn, Lynn, additional, Slocumb, Roberta, additional, Dabbs, Christy, additional, Espinoza, Raffaella, additional, Aird, Karen, additional, Beran, Todd, additional, Rubertone, Jim, additional, Slack, Stephen, additional, Oh, Junhie, additional, Janes, Tiffany, additional, Schwartz, Stephen, additional, Chiodini, Stephanie, additional, Hurley, Deborah, additional, Whiteside, Martin, additional, Rai, Saroj, additional, Williams, Melanie, additional, Herget, Kim, additional, Sweeney, Carol, additional, Johnson, Alison, additional, Keitheri Cheteri, Mahesh, additional, Migliore Santiago, Patti, additional, Blankenship, Steven, additional, Farley, Shawn, additional, Borchers, Robert, additional, Malicki, Robin, additional, Espinoza, Julia, additional, Grandpre, Joseph, additional, Edwards, Brenda, additional, Mariotto, Angela, additional, Weir, Hannah, additional, Wilson, Reda, additional, Wang, Ning, additional, Yang, Lei, additional, Chen, Jian-Shun, additional, He, Yu-Tong, additional, Song, Guo-Hui, additional, Gu, Xiao-Ping, additional, Mei, Dan, additional, Ge, Heng-Ming, additional, Wu, Tong-Hao, additional, Li, Yan-Yan, additional, Zhao, De-Li, additional, Jin, Feng, additional, Zhang, Jian-Hua, additional, Zhu, Feng-Dong, additional, Junhua, Qian, additional, Yang, Yan Lei, additional, Jiang, Chun-Xiao, additional, Biao, Wang, additional, Wang, Jian, additional, Li, Qi-Long, additional, Yi, He, additional, Zhou, Xin, additional, Dong, JianMei, additional, Li, WeiWei, additional, Fu, Fang-Xian, additional, Chen, Jian-Guo, additional, Zhu, Jian, additional, Li, Yan-Hua, additional, Lu, Yu-Qiang, additional, Fan, Min, additional, Huang, Su-Qin, additional, Guo, Guo-Ping, additional, Zhaolai, Hua, additional, Wei, Kuangrong, additional, Chen, Wan-Qing, additional, Wei, Wenqiang, additional, Zeng, Hongmei, additional, Demetriou, Anna, additional, Mang, Wai Kong, additional, Ngan, Kai Cheong, additional, Kataki, Amal, additional, Krishnatreya, Manigreeva, additional, Jayalekshmi, Padmavathi Amma, additional, Sebastian, Paul, additional, George, Preethi, additional, Mathew, Aleyamma, additional, Nandakumar, Ambakumar, additional, Malekzadeh, Reza, additional, Roshandel, Gholamreza, additional, Keinan-Boker, Lital, additional, Silverman, Barbara, additional, Ito, Hidemi, additional, Koyanagi, Yuriko, additional, Sato, Masako, additional, Tobori, Fumio, additional, Nakata, Ichiro, additional, Teramoto, Norihiro, additional, Hattori, Masakazu, additional, Kaizaki, Yasuharu, additional, Moki, Fumitaka, additional, Sugiyama, Hiromi, additional, Utada, Mai, additional, Nishimura, Makiko, additional, Yoshida, Keiichi, additional, Kurosawa, Katsuki, additional, Nemoto, Yuji, additional, Narimatsu, Hiroto, additional, Sakaguchi, Masahiko, additional, Kanemura, Seiki, additional, Naito, Michiko, additional, Narisawa, Rintaro, additional, Miyashiro, Isao, additional, Mori, Daisuke, additional, Yoshitake, Mayuko, additional, Oki, Izumi, additional, Fukushima, Norimasa, additional, Shibata, Akiko, additional, Iwasa, Keiichiro, additional, Ono, Chie, additional, Matsuda, Tomohiro, additional, Nimri, Omar, additional, Jung, Kyu-Won, additional, Won, Young-Joo, additional, Alawadhi, Eiman, additional, Elbasmi, Amani, additional, Ab Manan, Azizah, additional, Adam, Farzaana, additional, Nansalmaa, Erdenekhuu, additional, Tudev, Undarmaa, additional, Ochir, Chimedsuren, additional, Al Khater, Al Hareth, additional, El Mistiri, Mufid, additional, Lim, Gek Hsiang, additional, Teo, Yik Ying, additional, Chiang, Chun-Ju, additional, Lee, Wen-Chung, additional, Buasom, Rangsiya, additional, Sangrajrang, Suleeporn, additional, Suwanrungruang, Krittika, additional, Vatanasapt, Patravoot, additional, Daoprasert, Karnchana, additional, Pongnikorn, Donsuk, additional, Leklob, Atit, additional, Sangkitipaiboon, Somphob, additional, Geater, Sarayut, additional, Sriplung, Hutcha, additional, Ceylan, Okan, additional, Kög, Iskender, additional, Dirican, Oya, additional, Köse, Tülay, additional, Gurbuz, Tulın, additional, Karašahin, Füsun Emine, additional, Turhan, Duygu, additional, Aktaş, Umut, additional, Halat, Yakup, additional, Eser, Sultan, additional, Yakut, Cankut, additional, Altinisik, Merve, additional, Cavusoglu, Yasar, additional, Türkköylü, Ayşe, additional, Üçüncü, Nuršen, additional, Hackl, Monika, additional, Zborovskaya, Anna, additional, Aleinikova, Olga, additional, Henau, Kris, additional, Van Eycken, Liesbet, additional, Atanasov, Trayan, additional, Valerianova, Zdravka, additional, Šekerija, Mario, additional, Dušek, Ladislav, additional, Zvolský, Miroslav, additional, Steinrud Mørch, Lina, additional, Storm, Hans, additional, Wessel Skovlund, Charlotte, additional, Innos, Kaire, additional, Malila, Nea, additional, Jégu, Jérémie, additional, Velten, Michel, additional, Cornet, Edouard, additional, Troussard, Xavier, additional, Bouvier, Anne-Marie, additional, Guizard, Anne-Valérie, additional, Bouvier, Véronique, additional, Launoy, Guy, additional, Dabakuyo Yonli, Sandrine, additional, Poillot, Marie-Laure, additional, Maynadié, Marc, additional, Mounier, Morgane, additional, Vaconnet, Lina, additional, Woronoff, Anne-Sophie, additional, Daoulas, Mélanie, additional, Robaszkiewicz, Michel, additional, Clavel, Jacqueline, additional, Poulalhon, Claire, additional, Desandes, Emmanuel, additional, Lacour, Brigitte, additional, Baldi, Isabelle, additional, Pouchieu, Camille, additional, Amadeo, Brice, additional, Coureau, Gaëlle, additional, Monnereau, Alain, additional, Audoin, Magali, additional, D'Almeida, Tania, additional, Boyer, Séverine, additional, Hammas, Karima, additional, Trétarre, Brigitte, additional, Colonna, Marc, additional, Delafosse, Patricia, additional, Plouvier, Sandrine, additional, Cowppli-Bony, Anne, additional, Molinié, Florence, additional, Bara, Simona, additional, Ganry, Olivier, additional, Lapôtre-Ledoux, Bénédicte, additional, Daubisse-Marliac, Laetitia, additional, Bossard, Nadine, additional, Estève, Jacques, additional, Uhry, Zoé, additional, Stabenow, Roland, additional, Wilsdorf-Köhler, Heide, additional, Eberle, Andrea, additional, Luttmann, Sabine, additional, Löhden, Imma, additional, Nennecke, Alice, additional, Kieschke, Joachim, additional, Sirri, Eunice, additional, Justenhoven, Christina, additional, Zeissig, Sylke, additional, Holleczek, Bernd, additional, Eisemann, Nora, additional, Katalinic, Alexander, additional, Asquez, Rachelle, additional, Kumar, Vijay, additional, Petridou, Eleni, additional, Ólafsdóttir, Elínborg, additional, Tryggvadóttir, Laufey, additional, Murray, Deirdre, additional, Walsh, Paul, additional, Sundseth, Hildrun, additional, Mazzoleni, Guido, additional, Vittadello, Fabio, additional, Coviello, Enzo, additional, Cuccaro, Francesco, additional, Galasso, Rocco, additional, Sampietro, Giuseppe, additional, Magoni, Michele, additional, Ardizzone, Antonino, additional, D'Argenzio, Angelo, additional, Di Prima, Alessia Anna, additional, Ippolito, Antonella, additional, Lavecchia, Anna Maria, additional, Sutera Sardo, Antonella, additional, Gola, Gemma, additional, Ballotari, Paola, additional, Giacomazzi, Erica, additional, Ferretti, Stefano, additional, Dal Maso, Luigino, additional, Serraino, Diego, additional, Celesia, Maria Vittoria, additional, Filiberti, Rosa Angela, additional, Pannozzo, Fabio, additional, Melcarne, Anna, additional, Quarta, Fabrizio, additional, Andreano, Anita, additional, Russo, Antonio Giampiero, additional, Carrozzi, Giuliano, additional, Cirilli, Claudia, additional, Cavalieri d'Oro, Luca, additional, Rognoni, Magda, additional, Fusco, Mario, additional, Vitale, Maria Francesca, additional, Usala, Mario, additional, Cusimano, Rosanna, additional, Mazzucco, Walter, additional, Michiara, Maria, additional, Sgargi, Paolo, additional, Boschetti, Lorenza, additional, Chiaranda, Giorgio, additional, Seghini, Pietro, additional, Maule, Milena, additional, Merletti, Franco, additional, Spata, Eugenia, additional, Tumino, Rosario, additional, Mancuso, Pamela, additional, Vicentini, Massimo, additional, Cassetti, Tiziana, additional, Sassatelli, Romano, additional, Falcini, Fabio, additional, Giorgetti, Stefania, additional, Caiazzo, Anna Luisa, additional, Cavallo, Rossella, additional, Piras, Daniela, additional, Bella, Francesca, additional, Madeddu, Anselmo, additional, Fanetti, Anna Clara, additional, Maspero, Sergio, additional, Carone, Simona, additional, Mincuzzi, Antonia, additional, Candela, Giuseppa, additional, Scuderi, Tiziana, additional, Gentilini, Maria Adalgisa, additional, Rizzello, Roberto, additional, Rosso, Stefano, additional, Zanetti, Roberto, additional, Caldarella, Adele, additional, Intrieri, Teresa, additional, Bianconi, Fortunato, additional, Stracci, Fabrizio, additional, Contiero, Paolo, additional, Tagliabue, Giovanna, additional, Rugge, Massimo, additional, Zorzi, Manuel, additional, Beggiato, Simonetta, additional, Brustolin, Angelita, additional, De Angelis, Roberta, additional, Gatta, Gemma, additional, Maurina, Anita, additional, Oniščuka, Marija, additional, Mousavi, Mohsen, additional, Lipunova, Nadezda, additional, Vincerzevskienė, Ieva, additional, Agius, Dominic, additional, Calleja, Neville, additional, Siesling, Sabine, additional, Visser, Otto, additional, Johannesen, Tom, additional, Trojanowski, Maciej, additional, Mierzwa, Tomasz, additional, Rachtan, Jadwiga, additional, Kępska, Kamila, additional, Kościańska, Beata, additional, Wójcik-Tomaszewska, Joanna, additional, Motnyk, Marcin, additional, Gos, Anna, additional, Bielska-Lasota, Magdalena, additional, Didkowska, Joanna, additional, Wojciechowska, Urszula, additional, Forjaz de Lacerda, Gonçalo, additional, Rego, Raul, additional, Carrito, Branca, additional, Pais, Ana, additional, Bento, Maria José, additional, Rodrigues, Jessica, additional, Lourenço, Antonio, additional, Mayer-da-Silva, Alexandra, additional, Blaga, Luminita, additional, Coza, Daniela, additional, Gusenkova, Lubov, additional, Lazarevich, Olga, additional, Prudnikova, Olga, additional, Vjushkov, Dmitri Mikhailovich, additional, Egorova, Alla, additional, Orlov, Andrey, additional, Pikalova, Lidiya, additional, Zhuikova, Lilia, additional, Adamcik, Juraj, additional, Safaei Diba, Chakameh, additional, Zadnik, Vesna, additional, Zagar, Tina, additional, De-La-Cruz, Marta, additional, Lopez-de-Munain, Arantza, additional, Aleman, Araceli, additional, Rojas, Dolores, additional, Chillarón, Rosario Jiménez, additional, Navarro, Ana Isabel Marcos, additional, Puigdemont, Montse, additional, Sánchez Perez, María-José, additional, Franch Sureda, Paula, additional, Ramos Montserrat, Maria, additional, Chirlaque López, Maria Dolores, additional, Sánchez Gil, Antonia, additional, Ardanaz, Eva, additional, Guevara, Marcela, additional, Cañete-Nieto, Adela, additional, Peris-Bonet, Rafael, additional, Carulla, Marià, additional, Galceran, Jaume, additional, Almela, Fernando, additional, Sabater, Consol, additional, Khan, Staffan, additional, Pettersson, David, additional, Dickman, Paul, additional, Staehelin, Katharina, additional, Struchen, Benjamin, additional, Herrmann, Christian, additional, Mousavi, Seyed Mohsen, additional, Egger Hayoz, Céline, additional, Bouchardy, Christine, additional, Schaffar, Robin, additional, Went, Philip, additional, Maspoli-Conconi, Manuela, additional, Kuehni, Claudia, additional, Bordoni, Andrea, additional, Ortelli, Laura, additional, Chiolero, Arnaud, additional, Konzelmann, Isabelle, additional, Rohrmann, Sabine, additional, Wanner, Miriam, additional, Broggio, John, additional, Rashbass, Jem, additional, Fitzpatrick, Deirdre, additional, Gavin, Anna, additional, Morrison, David, additional, Thomson, Catherine, additional, Greene, Giles, additional, Huws, Dyfed, additional, Coleman, Michel, additional, Matz, Melissa, additional, Sanz, Natalia, additional, Ssenyonga, Naomi, additional, Stephens, Richard, additional, Chalker, Elizabeth, additional, Smith, Mirka, additional, Gugusheff, Jessica, additional, You, Hui, additional, Qin Li, Shu, additional, Dugdale, Sarah, additional, Moore, Julie, additional, Philpot, Shoni, additional, Pfeiffer, Rhonda, additional, Thomas, Helen, additional, Silva Ragaini, Bruna, additional, Venn, Alison, additional, Evans, Sue, additional, Te Marvelde, Luc, additional, Savietto, Vedrana, additional, Trevithick, Richard, additional, Currow, David, additional, and Lewis, Chris, additional

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2022
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34. Colonoscopic surveillance of first-degree relatives of colorectal cancer patients in a faecal occult blood screening programme

Author

Sassoli de Bianchi, Priscilla, Campari, Cinzia, Mancini, Silvia, Giuliani, Orietta, Landi, Patrizia, Paterlini, Luisa, Naldoni, Carlo, Finarelli, Alba C., Falcini, Fabio, Ponz de Leon, Maurizio, Sassatelli, Romano, Borciani, Elisabetta, Fornari, Fabio, Gatti, Giorgio, Zatelli, Marella, Zurlini, Corrado, Rossi, Federica, Corradini, Rossella, Olivetti, Rossella, Manfredi, Marilena, Baldazzi, Paola, Nannini, Roberto, Zanarini, Stefano, Matarese, Vincenzo G., Palmonari, Caterina, Triossi, Omero, Gordini, Sonia, Vattiato, Rosa, Colamartini, Americo, Palazzi, Mauro, Severi, Mirna, Briganti, Laura, Giovanardi, Mauro, Casale, Coralba, and Bucchi, Lauro

Published
2013
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35. Results of Compliant Participation in Five Rounds of Fecal Immunochemical Test Screening for Colorectal Cancer

Author

Baldacchini, Flavia, primary, Bucchi, Lauro, additional, Giuliani, Orietta, additional, Mancini, Silvia, additional, Ravaioli, Alessandra, additional, Vattiato, Rosa, additional, Giorgi Rossi, Paolo, additional, Campari, Cinzia, additional, Canuti, Debora, additional, Di Felice, Enza, additional, Mezzetti, Francesca, additional, Sassoli de Bianchi, Priscilla, additional, Ferretti, Stefano, additional, Falcini, Fabio, additional, Ventura, Chiara, additional, Baldacchini, Flavia, additional, Colamartini, Americo, additional, Signorelli, Dario, additional, Aragona, Giovanni, additional, Pennini, Francesca, additional, Chiaranda, Giorgio, additional, Seghini, Pietro, additional, Fiora, Cristian Dalla, additional, Fattibene, Claudio, additional, Michiara, Maria, additional, Orsi, Paolo, additional, Rossi, Paolo Giorgi, additional, Mangone, Lucia, additional, Sassatelli, Romano, additional, Carrozzi, Giuliano, additional, Rossi, Federica, additional, Esposito, Pasqualina, additional, Trande, Paolo, additional, Viani, Simona, additional, Ricciardiello, Luigi, additional, Cennamo, Vincenzo, additional, Gualandi, Giovanna, additional, Caprara, Licia, additional, De Lillo, Margherita, additional, De Togni, Aldo, additional, Palmonari, Caterina, additional, Pasquali, Daniela, additional, Zoli, Giorgio, additional, Re, Serena Dal, additional, Petrini, Chiara, additional, Serafini, Monica, additional, Triossi, Omero, additional, Vitali, Benedetta, additional, Gallinucci, Mara, additional, Imolesi, Claudia, additional, Palazzi, Mauro, additional, Fabbri, Carlo, additional, Casale, Coralba, additional, Giovanardi, Mauro, additional, and Trombetti, Daniele, additional

Published
2021
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37. Ki-67 cytological index can distinguish well-differentiated from poorly differentiated pancreatic neuroendocrine tumors: a comparative cytohistological study of 53 cases

Author

Carlinfante, Gabriele, Baccarini, Paola, Berretti, Debora, Cassetti, Tiziana, Cavina, Maurizio, Conigliaro, Rita, De Pellegrin, Alessandro, Di Tommaso, Luca, Fabbri, Carlo, Fornelli, Adele, Frasoldati, Andrea, Gardini, Giorgio, Losi, Luisa, Maccio, Livia, Manta, Raffaele, Pagano, Nico, Sassatelli, Romano, Serra, Silvia, and Camellini, Lorenzo

Published
2014
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38. Alcohol-related liver disease phenotype impacts survival after an acute variceal bleeding episode

Author

Villagrasa, Ares, Hernández-Gea, Virginia, Bataller, Ramon, Giráldez, Álvaro, Procopet, Bogdan, Amitrano, Lucio, Villanueva, Candid, Thabut, Dominique, Ibañez-Samaniego, Luis, Albillos, Agustin, Bureau, Christophe, Trebicka, Jonel, Llop, Elba, Laleman, Wim, Palazon, J M, Castellote, Jose, Rodrigues, Susana, Gluud, Lise L, Ferreira, Carlos N, Cañete, Nuria, Rodríguez, Manuel, Ferlitsch, Arnulf, Mundi, Jose L, Gronbaek, Henning, Hernández-Guerra, Manuel, Sassatelli, Romano, Dell'Era, Alessandra, Senzolo, Marco, Abraldes, Juan G, Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Primignani, Massimo, Krag, Aleksander, Silva-Junior, Gilberto, Romero-Gómez, Manuel, Tantau, Marcel, Guardascione, Maria A, Alvarado, Edilmar, Rudler, Marika, Bañares, Rafael, Martinez, Javier, Robic, Marie A, Jansen, Christian, Calleja, Jose L, Nevens, Frederik, Bosch, Jaime, Ventura-Cots, Meritxell, García-Pagan, Juan C, and Genescà, Joan

Subjects
alcohol, upper gastrointestinal bleeding, cirrhosis, alcohol-related hepatitis, 610 Medicine & health, abstinence
Abstract

BACKGROUND & AIMS Alcohol-related hepatitis (AH) encompasses a high mortality. AH might be a concomitant event in patients with acute variceal bleeding (AVB). The current study aimed to assess the prevalence of AH in patients with AVB and to compare the clinical outcomes of AH patients to other alcohol-related liver disease (ALD) phenotypes and viral cirrhosis. METHODS Multicentre, observational study including 916 patients with AVB falling under the next categories: AH (n = 99), ALD cirrhosis actively drinking (d-ALD) (n = 285), ALD cirrhosis abstinent from alcohol (a-ALD) (n = 227) and viral cirrhosis (n = 305). We used a Cox proportional hazards model to calculate adjusted hazard ratio (HR) of death adjusted by MELD. RESULTS The prevalence of AH was 16% considering only ALD patients. AH patients exhibited more complications. Forty-two days transplant-free survival was worse among AH, but statistical differences were only observed between AH and d-ALD groups (84 vs. 93%; p = 0.005), when adjusted by MELD no differences were observed between AH and the other groups. At one-year, survival of AH patients (72.7%) was similar to the other groups; when adjusted by MELD mortality HR was better in AH compared to a-ALD (0.48; 0.29-0.8, p = 0.004). Finally, active drinkers who remained abstinent presented better survival, independently of having AH. CONCLUSIONS Contrary to expected, AH patients with AVB present no worse one-year survival than other patients with different alcohol-related phenotypes or viral cirrhosis. Abstinence influences long-term survival and could explain these counterintuitive results.

Published
2021

39. Bacterial infections in patients with acute variceal bleeding in the era of antibiotic prophylaxis

Author

Martínez, Javier, primary, Hernández-Gea, Virginia, additional, Rodríguez-de-Santiago, Enrique, additional, Téllez, Luis, additional, Procopet, Bogdan, additional, Giráldez, Álvaro, additional, Amitrano, Lucio, additional, Villanueva, Candid, additional, Thabut, Dominique, additional, Ibañez-Samaniego, Luis, additional, Silva-Junior, Gilberto, additional, Genescà, Joan, additional, Bureau, Christophe, additional, Trebicka, Jonel, additional, Bañares, Rafael, additional, Krag, Aleksander, additional, Llop, Elba, additional, Laleman, Wim, additional, Palazon, Jose María, additional, Castellote, Jose, additional, Rodrigues, Susana, additional, Gluud, Lise L., additional, Noronha-Ferreira, Carlos, additional, Cañete, Nuria, additional, Rodríguez, Manuel, additional, Ferlitsch, Arnulf, additional, Schwarzer, Remy, additional, Mundi, Jose Luis, additional, Gronbaek, Henning, additional, Hernández-Guerra, Manuel, additional, Sassatelli, Romano, additional, Dell'Era, Alessandra, additional, Senzolo, Marco, additional, Abraldes, Juan G., additional, Romero-Gomez, Manuel, additional, Zipprich, Alexander, additional, Casas, Meritxell, additional, Masnou, Helena, additional, Primignani, Massimo, additional, Nevens, Frederik, additional, Calleja, Jose Luis, additional, Jansen, Christian, additional, Robic, Marie Angèle, additional, Conejo, Irene, additional, Catalina, Maria Vega, additional, Rudler, Marika, additional, Alvarado, Edilmar, additional, Perez-Campuzano, Valeria, additional, Guardascione, Maria Anna, additional, Fischer, Petra, additional, Bosch, Jaime, additional, García-Pagán, Juan Carlos, additional, and Albillos, Agustín, additional

Published
2021
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40. Quality of colonoscopy in an organised colorectal cancer screening programme with immunochemical faecal occult blood test: the EQuIPE study (Evaluating Quality Indicators of the Performance of Endoscopy)

Author

Zorzi, Manuel, Senore, Carlo, Da Re, Filippo, Barca, Alessandra, Bonelli, Luigina Ada, Cannizzaro, Renato, Fasoli, Renato, Di Furia, Lucia, Di Giulio, Emilio, Mantellini, Paola, Naldoni, Carlo, Sassatelli, Romano, Rex, Douglas, Hassan, Cesare, Zappa, Marco, Campari, Cinzia, Falcini, Fabio, Giuliani, Orietta, Triossi, Omero, Matarese, Vincenzo, Fedato, Chiara, Baracco, Susanna, Monica, Fabio, Quadrino, Francesco, Landi, Patrizia, Buscarini, Elisabetta, de Pretis, Giovanni, Occhipinti, Pietro, Arrigoni, Arrigo, and Grassini, Mario

Published
2015
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43. Prevalence Rates of Gallstone Disease in Italy: The Chianciano Population Study

Author

Loria, Paola, Dilengite, Michele A., Bozzoli, Mara, Carubbi, Francesca, Messora, Roberto, Sassatelli, Romano, Bertolotti, Marco, Tampieri, Auro, Tartoni, Pier Luigi, Cassinadri, Mariateresa, Della Ciana, Mario, Contemori, Maurizio, Save, Nicola, Sordi, Bruno, Alimenti, Giulio, Fabrizi, Fabrizio, Buciuni, Angelo, and Carulli, Nicola

Published
1994

45. Bacterial infections in patients with acute variceal bleeding in the era of antibiotic prophylaxis

Author

Ministerio de Ciencia e Innovación (España), Instituto de Salud Carlos III, Generalitat de Catalunya, European Commission, Martínez, Javier, Hernández-Gea, Virginia, Rodríguez-de-Santiago, Enrique, Téllez, Luis, Procopet, Bogdan, Giráldez, Álvaro, Amitrano, Lucio, Villanueva, Candid, Thabut, Dominique, Ibáñez-Samaniego, Luis, Silva-Junior, Gilberto, Genescà, Joan, Bureau, Christophe, Trebicka, Jonel, Bañares, Rafael, Krag, Aleksander, Llop, Elba, Laleman, Wim, Palazón, Jose María, Castellote, José, Rodrigues, Susana, Gluud, Lise L., Noronha-Ferreira, Carlos, Cañete, Nuria, Rodríguez, Manuel, Ferlitsch, Arnulf, Schwarzer, Remy, Mundi, José Luis, Gronbaek, Henning, Hernández-Guerra, Manuel, Sassatelli, Romano, Dell'Era, Alessandra, Senzolo, Marco, Abraldes, Juan G., Romero-Gómez, Manuel, Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Primignani, Massimo, Nevens, Frederik, Calleja, José Luis, Jansen, Christian, Robic, Marie Angèle, Conejo, Irene, Catalina, María Vega, Rudler, Marika, Alvarado, Edilmar, Pérez-Campuzano, Valeria, Guardascione, Maria Anna, Fischer, Petra, Bosch, Jaime, García-Pagán, Juan Carlos, Albillos, Agustín, Ministerio de Ciencia e Innovación (España), Instituto de Salud Carlos III, Generalitat de Catalunya, European Commission, Martínez, Javier, Hernández-Gea, Virginia, Rodríguez-de-Santiago, Enrique, Téllez, Luis, Procopet, Bogdan, Giráldez, Álvaro, Amitrano, Lucio, Villanueva, Candid, Thabut, Dominique, Ibáñez-Samaniego, Luis, Silva-Junior, Gilberto, Genescà, Joan, Bureau, Christophe, Trebicka, Jonel, Bañares, Rafael, Krag, Aleksander, Llop, Elba, Laleman, Wim, Palazón, Jose María, Castellote, José, Rodrigues, Susana, Gluud, Lise L., Noronha-Ferreira, Carlos, Cañete, Nuria, Rodríguez, Manuel, Ferlitsch, Arnulf, Schwarzer, Remy, Mundi, José Luis, Gronbaek, Henning, Hernández-Guerra, Manuel, Sassatelli, Romano, Dell'Era, Alessandra, Senzolo, Marco, Abraldes, Juan G., Romero-Gómez, Manuel, Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Primignani, Massimo, Nevens, Frederik, Calleja, José Luis, Jansen, Christian, Robic, Marie Angèle, Conejo, Irene, Catalina, María Vega, Rudler, Marika, Alvarado, Edilmar, Pérez-Campuzano, Valeria, Guardascione, Maria Anna, Fischer, Petra, Bosch, Jaime, García-Pagán, Juan Carlos, and Albillos, Agustín

Abstract

[Background & Aims] Antibiotic prophylaxis reduces the risk of infection and mortality in patients with cirrhosis and acute variceal bleeding (AVB). This study examines the incidence of, and risk factors for, bacterial infections during hospitalization in patients with AVB on antibiotic prophylaxis., [Methods] A post hoc analysis was performed using the database of an international, multicenter, observational study designed to examine the role of pre-emptive transjugular intrahepatic portosystemic shunts in patients with cirrhosis and AVB. Data were collected on patients with cirrhosis hospitalized for AVB (n = 2,138) from a prospective cohort (October 2013-May 2015) at 34 referral centers, and a retrospective cohort (October 2011-September 2013) at 19 of these centers. The primary outcome was incidence of bacterial infection during hospitalization., [Results] A total of 1,656 patients out of 1,770 (93.6%) received antibiotic prophylaxis; third-generation cephalosporins (76.2%) and quinolones (19.0%) were used most frequently. Of the patients on antibiotic prophylaxis, 320 patients developed bacterial infection during hospitalization. Respiratory infection accounted for 43.6% of infections and for 49.7% of infected patients, and occurred early after admission (median 3 days, IQR 1-6). On multivariate analysis, respiratory infection was independently associated with Child-Pugh C (odds ratio [OR] 3.1; 95% CI 1.4-6.7), grade III-IV encephalopathy (OR 2.8; 95% CI 1.8-4.4), orotracheal intubation for endoscopy (OR 2.6; 95% CI 1.8-3.8), nasogastric tube placement (OR 1.7; 95% CI 1.2-2.4) or esophageal balloon tamponade (OR 2.4; 95% CI 1.2-4.9)., [Conclusion] Bacterial infections develop in almost one-fifth of patients with AVB despite antibiotic prophylaxis. Respiratory infection is the most frequent, is an early event after admission, and is associated with advanced liver failure, severe hepatic encephalopathy and use of nasogastric tube, orotracheal intubation for endoscopy or esophageal balloon tamponade.

Published
2021

47. Impact of multidisciplinary approach and radiologic review on surgical outcome and overall survival of patients with pancreatic cancer: a retrospective cohort study

Author

Artioli, Giulia, primary, Besutti, Giulia, additional, Cassetti, Tiziana, additional, Sereni, Giuliana, additional, Zizzo, Maurizio, additional, Bonacini, Stefano, additional, Carlinfante, Gabriele, additional, Panebianco, Michele, additional, Cavazza, Alberto, additional, Pinto, Carmine, additional, Sassatelli, Romano, additional, Pattacini, Pierpaolo, additional, and Giorgi Rossi, Paolo, additional

Published
2021
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48. Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS

Author

Trebicka, Jonel, Gu, Wenyi, Ibáñez-Samaniego, Luis, Hernández-Gea, Virginia, Pitarch, Carla, Garcia, Elisabet, Procopet, Bogdan, Giráldez, Álvaro, Amitrano, Lucio, Villanueva, Candid, Thabut, Dominique, Silva-Junior, Gilberto, Martinez, Javier, Genescà, Joan, Bureau, Cristophe, Llop, Elba, Laleman, Wim, Palazon, Jose Maria, Castellote, Jose, Rodrigues, Susanag, Gluud, Liselotte, Ferreira, Carlos Noronha, Barcelo, Rafael, Cañete, Nuria, Rodríguez, Manuel, Ferlitsch, Arnulf, Mundi, Jose Luis, Gronbaek, Henning, Hernández-Guerra, Manuel, Sassatelli, Romano, Dell'Era, Alessandra, Senzolo, Marco, Abraldes, Juan G., Romero-Gómez, Manuel, Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Primignani, Massimo, Weiss, Emmanuel, Catalina, Maria Vega, Erasmus, Hans Peter, Uschner, Frank Erhard, Schulz, Martin, Brol, Maximilian J., Praktiknjo, Michael, Chang, Johannes, Krag, Aleksander, Nevens, Frederik, Calleja, Jose Luis, Robic, Marie Angèle, Trebicka, Jonel, Gu, Wenyi, Ibáñez-Samaniego, Luis, Hernández-Gea, Virginia, Pitarch, Carla, Garcia, Elisabet, Procopet, Bogdan, Giráldez, Álvaro, Amitrano, Lucio, Villanueva, Candid, Thabut, Dominique, Silva-Junior, Gilberto, Martinez, Javier, Genescà, Joan, Bureau, Cristophe, Llop, Elba, Laleman, Wim, Palazon, Jose Maria, Castellote, Jose, Rodrigues, Susanag, Gluud, Liselotte, Ferreira, Carlos Noronha, Barcelo, Rafael, Cañete, Nuria, Rodríguez, Manuel, Ferlitsch, Arnulf, Mundi, Jose Luis, Gronbaek, Henning, Hernández-Guerra, Manuel, Sassatelli, Romano, Dell'Era, Alessandra, Senzolo, Marco, Abraldes, Juan G., Romero-Gómez, Manuel, Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Primignani, Massimo, Weiss, Emmanuel, Catalina, Maria Vega, Erasmus, Hans Peter, Uschner, Frank Erhard, Schulz, Martin, Brol, Maximilian J., Praktiknjo, Michael, Chang, Johannes, Krag, Aleksander, Nevens, Frederik, Calleja, Jose Luis, and Robic, Marie Angèle

Abstract

Background & Aims: The relationship between acute-on-chronic liver failure (ACLF) and acute variceal bleeding (AVB) is poorly understood. Specifically, the prevalence and prognosis of ACLF in the context of AVB is unclear, while the role of transjugular intrahepatic portosystemic shunt (TIPS) in the management in patients with ACLF has not been described to date. Methods: A multicenter, international, observational study was conducted in 2,138 patients from 34 centers between 2011 and 2015. ACLF was defined and graded according to the EASL-CLIF consortium definition. Placement of pre-emptive TIPS (pTIPS) was based on individual center policy. Patients were followed-up for 1 year, until death or liver transplantation. Cox regression and competing risk models (Gray's test) were used to identify independent predictors of rebleeding or mortality. Results: At admission, 380/2,138 (17.8%) patients had ACLF according to EASL-CLIF criteria (grade 1: 38.7%; grade 2: 39.2%; grade 3: 22.1%). The 42-day rebleeding (19% vs. 10%; p <0.001) and mortality (47% vs. 10%; p <0.001) rates were higher in patients with ACLF and increased with ACLF grades. Of note, the presence of ACLF was independently associated with rebleeding and mortality. pTIPS placement improved survival in patients with ACLF at 42 days and 1 year. This effect was also observed in propensity score matching analysis of 66 patients with ACLF, of whom 44 received pTIPs and 22 did not. Conclusions: This large multicenter international real-life study identified ACLF at admission as an independent predictor of rebleeding and mortality in patients with AVB. Moreover, pTIPS was associated with improved survival in patients with ACLF and AVB. Lay summary: Acute variceal bleeding is a deadly complication of liver cirrhosis that results from severe portal hypertension. This study demonstrates that the presence of acute-on-chronic liver failure (ACLF) is the strongest predictor of mortality in patients with acute

Published
2020

49. Endoscopic resection of a choledochocele

Author

Mirante, Vincenzo Giorgio, additional, Cecinato, Paolo, additional, Grillo, Simone, additional, Sereni, Giuliana, additional, Lucarini, Matteo, additional, Beltrami, Marina, additional, and Sassatelli, Romano, additional

Published
2020
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50. Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS

Author

Trebicka, Jonel, primary, Gu, Wenyi, additional, Ibáñez-Samaniego, Luis, additional, Hernández-Gea, Virginia, additional, Pitarch, Carla, additional, Garcia, Elisabet, additional, Procopet, Bogdan, additional, Giráldez, Álvaro, additional, Amitrano, Lucio, additional, Villanueva, Candid, additional, Thabut, Dominique, additional, Silva-Junior, Gilberto, additional, Martinez, Javier, additional, Genescà, Joan, additional, Bureau, Cristophe, additional, Llop, Elba, additional, Laleman, Wim, additional, Palazon, Jose Maria, additional, Castellote, Jose, additional, Rodrigues, Susanag, additional, Gluud, Liselotte, additional, Ferreira, Carlos Noronha, additional, Barcelo, Rafael, additional, Cañete, Nuria, additional, Rodríguez, Manuel, additional, Ferlitsch, Arnulf, additional, Mundi, Jose Luis, additional, Gronbaek, Henning, additional, Hernández-Guerra, Manuel, additional, Sassatelli, Romano, additional, Dell'Era, Alessandra, additional, Senzolo, Marco, additional, Abraldes, Juan G., additional, Romero-Gómez, Manuel, additional, Zipprich, Alexander, additional, Casas, Meritxell, additional, Masnou, Helena, additional, Primignani, Massimo, additional, Weiss, Emmanuel, additional, Catalina, Maria-Vega, additional, Erasmus, Hans-Peter, additional, Uschner, Frank Erhard, additional, Schulz, Martin, additional, Brol, Maximilian J., additional, Praktiknjo, Michael, additional, Chang, Johannes, additional, Krag, Aleksander, additional, Nevens, Frederik, additional, Calleja, Jose Luis, additional, Robic, Marie Angèle, additional, Conejo, Irene, additional, Albillos, Agustin, additional, Rudler, Marika, additional, Alvarado, Edilmar, additional, Guardascione, Maria Anna, additional, Tantau, Marcel, additional, Bosch, Jaime, additional, Torres, Ferran, additional, Pavesi, Marco, additional, Garcia-Pagán, Juan Carlos, additional, Jansen, Christian, additional, and Bañares, Rafael, additional

Published
2020
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