29 results on '"Sagi, Sarah A."'
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2. Substrate-targeting γ-secretase modulators
3. Diverse compounds mimic Alzheimer disease–causing mutations by augmenting Aβ42 production
4. A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
5. Inhibitors of Rho-kinase modulate amyloid-β (Aβ) secretion but lack selectivity for Aβ42
6. Rho-mediated cytoskeletal rearrangement in response to LPA is functionally antagonized by Rac1 and PIP2
7. NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo
8. A subset f NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
9. Substrate Sequence Influences γ-Secretase Modulator Activity, Role of the Transmembrane Domain of the Amyloid Precursor Protein
10. P2-338: Substrate-targeting gamma-secretase modulators
11. Safety, Tolerability, Pharmacokinetics, and Aβ Levels After Short-term Administration of R-flurbiprofen in Healthy Elderly Individuals
12. O4-05-03: A key role of the C-terminal cleavage of APP in Alzheimer's disease
13. Inhibitors of Rho‐kinase modulate amyloid‐β (Aβ) secretion but lack selectivity for Aβ42
14. P4-380 Inhibitors of the RHO effector RHO-kinase (rock) modulate Aβ secretion but lack selectivity for Aβ42
15. O3-06-02 Selective Abeta42 modifying agents: effects on Abeta deposition and behavior in TG2576 mice
16. Evidence That Nonsteroidal Anti-inflammatory Drugs Decrease Amyloid β42 Production by Direct Modulation of γ-Secretase Activity
17. Aβ42-lowering Nonsteroidal Anti-inflammatory Drugs Preserve Intramembrane Cleavage of the Amyloid Precursor Protein (APP) and ErbB-4 Receptor and Signaling through the APP Intracellular Domain
18. The Non-cyclooxygenase Targets of Non-steroidal Anti-inflammatory Drugs, Lipoxygenases, Peroxisome Proliferator-activated Receptor, Inhibitor of κB Kinase, and NFκB, Do Not Reduce Amyloid β42 Production
19. Nonsteroidal antiinflammatory drugs as therapeutic agents for Alzheimer's disease
20. Physical and Functional Interactions of Gαq with Rho and Its Exchange Factors
21. The Role of Rho in G Protein-Coupled Receptor Signal Transduction
22. Rho-mediated cytoskeletal rearrangement in response to LPA is functionally antagonized by Rac1 and PIP2.
23. The Non-cyclooxygenase Targets of Non-steroidal Anti-inflammatory Drugs, Lipoxygenases, Peroxisome Proliferator-activator Receptor, Amyloid β42 Production.
24. NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo.
25. NSAIDs and enantiomers of flurbiprofen target ϒ-secretase and lower AΒ42 in vivo.
26. Physical and Functional Interactions of Gαqwith Rho and Its Exchange Factors*
27. Rho-mediated cytoskeletal rearrangement in response to LPA is functionally antagonized by Rac1 and PIP2.
28. Inhibitors of Rho-kinase modulate amyloid-beta (Abeta) secretion but lack selectivity for Abeta42.
29. Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity.
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