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Substrate-targeting γ-secretase modulators
- Source :
- Nature. June 12, 2008, Vol. 453 Issue 7197, p925, 6 p.
- Publication Year :
- 2008
-
Abstract
- Selective lowering of Aβ42 levels (the 42-residue isoform of the amyloid-β peptide) with small-molecule γ-secretase modulators (GSMs), such as some non-steroidal anti-inflammatory drugs, is a promising therapeutic approach for Alzheimer's [...]
Details
- Language :
- English
- ISSN :
- 00280836
- Volume :
- 453
- Issue :
- 7197
- Database :
- Gale General OneFile
- Journal :
- Nature
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.183317736