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Objective: To update the clinical practice guidelines for the management of oral mucositis (OM) that were developed by the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO). This part focuses on honey, herbal compounds, saliva stimulants, probiotics, and miscellaneous agents.Methods: A systematic review was conducted by the Mucositis Study Group of MASCC/ISOO. The body of evidence for each intervention, in each clinical setting, was assigned an evidence level. The findings were added to the database used to develop the 2014 MASCC/ISOO clinical practice guidelines. Based on the evidence level, one of the following guidelines were determined: Recommendation, Suggestion, No Guideline Possible.Results: A total of 78 papers were identified within the scope of this section, of which 49 were included in this review and merged with nine publications that were reported in the previous guidelines update. A new Suggestion was made for honey (combined topical and systemic delivery) for the prevention of OM in head and neck cancer patients receiving radiotherapy with or without chemotherapy. A new Suggestion clarified that chewing gum is not effective for the prevention of OM in pediatric patients with hematological or solid cancer treated with chemotherapy. No guideline was possible for other interventions.Conclusions: Numerous natural products and herbal remedies were studied for the management of OM. Of the agents reviewed in this systematic review, a guideline in favor was made for honey (combined topical and systemic), while a guideline against was made for chewing gum. Additional research is warranted to clarify the potential of other interventions. [ABSTRACT FROM AUTHOR]

A Correction to this paper has been published: https://doi.org/10.1007/s00520-021-06141-9 [ABSTRACT FROM AUTHOR]

The article discusses the Oncology Nurses Societies (ONS) Putting Evidence Into Practice (PEP) resource cards. The cards contain evidence based nursing interventions for 16 patient outcomes. Nurse consultant Debra A. Parchen of the National Institutes of Health explains how she used them to educate nursing staff. Results of surveys measuring their use are also included.

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This article discusses growing controversy and questions from the public regarding the use of a human papillomavirus (HPV) vaccine in preteen girls in the U.S. It identifies several hurdles to HPV vaccination: the state mandate, the healthcare team, the parents and the religious community. It indicates several studies which show that few individuals have a clear understanding of HPV and its significance to certain infection and cancer.