294 results on '"S. Kiryu"'
Search Results
2. Usefulness of deep learning-based noise reduction for 1.5 T MRI brain images
- Author
-
T. Tajima, H. Akai, K. Yasaka, A. Kunimatsu, Y. Yamashita, M. Akahane, N. Yoshioka, O. Abe, K. Ohtomo, and S. Kiryu
- Subjects
Deep Learning ,Diffusion Magnetic Resonance Imaging ,Brain Neoplasms ,Humans ,Brain ,Radiology, Nuclear Medicine and imaging ,General Medicine ,Magnetic Resonance Imaging - Abstract
To evaluate 1.5 T magnetic resonance imaging (MRI) brain images with denoising procedures using deep learning-based reconstruction (dDLR) relative to the original 1.5 and 3 T images.Eleven volunteers underwent MRI at 3 and 1.5 T. Two-dimensional fast spin-echo T2-weighted imaging (T2WI), fluid-attenuated inversion recovery (FLAIR) imaging and diffusion-weighted imaging (DWI) sequences were performed. The dDLR method was applied to the 1.5 T data (dDLR-1.5 T), then the image quality of the dDLR-1.5 T data relative to the original 1.5 T and 3 T data was qualitatively and quantitatively assessed based on the structure similarity (SSIM) index; the signal-to-noise ratios (SNRs) of the grey matter (GM) and white matter (WM); and the contrast-to-noise ratios (CNRs) between the GM and WM (CNRgm-wm) and between the striatum (ST) and WM (CNRst-wm).The perceived image quality, and SNRs and CNRs were significantly higher for the dDLR-1.5 T images versus the 1.5 T images for all sequences and almost comparable or even superior to those of the 3 T images. For DWI, the SNRs and CNRst-wm were significantly higher for the dDLR-1.5 T images versus the 3 T images.The dDLR technique improved the image quality of 1.5 T brain MRI images. With respect to qualitative and quantitative measurements, the denoised 1.5 T brain images were almost equivalent or even superior to the 3 T brain images.
- Published
- 2022
3. Experimental Demonstration of Current Dependence Evaluation of Voltage Divider Based on Quantized Hall Resistance Voltage Divider
- Author
-
Nobu-Hisa Kaneko, Takehiko Oe, S. Kiryu, and Atsushi Domae
- Subjects
Resistive touchscreen ,Engineering ,business.industry ,Voltage divider ,Electrical engineering ,Chip ,01 natural sciences ,Metrology ,010309 optics ,0103 physical sciences ,Electronic engineering ,Electrical and Electronic Engineering ,Current (fluid) ,010306 general physics ,business ,Instrumentation ,Reference standards ,Voltage - Abstract
The National Metrology Institute of Japan has developed a resistive voltage divider (RVD), which is constructed from a series array of quantized Hall resistance (QHR) bars named “QHR voltage divider” fabricated on one chip. In principle, the QHR voltage divider does not need time-consuming bootstrap self-calibration and is not affected by measurement conditions such as ambient temperature and measurement current Therefore the QHR voltage divider is suitable for use as a reference standard for characteristic evaluation of conventional RVDs. In this paper, the evaluation of RVD current dependence based on the QHR voltage is demonstrated.
- Published
- 2017
- Full Text
- View/download PDF
4. Development of 7.75 Ratio Voltage Divider Toward a Precise Measurement of Decade Resistance Based on the AC Quantized Hall Resistance
- Author
-
Norihiko Sakamoto, Nobu-Hisa Kaneko, S. Kiryu, and Atsushi Domae
- Subjects
Engineering ,business.industry ,Voltage divider ,Mathematical analysis ,Electrical engineering ,Distribution transformer ,Metrology ,law.invention ,Electromagnetic coil ,law ,Bridge circuit ,Calibration ,Electrical and Electronic Engineering ,Resistor ,business ,Transformer ,Instrumentation - Abstract
At the National Metrology Institute of Japan, we are developing a transformer bridge circuit that can precisely compare the $i = 2$ plateau resistance in an ac quantized Hall resistance with a 100-k $\Omega $ resistance. In this paper, we propose a practical transformer voltage ratio of 7.75:1, which is the most important parameter for developing a transformer bridge circuit. Further, we describe the design of an inductive voltage divider (IVD) to realize the 7.75:1 ratio. We intend to use the proposed IVD as a reference standard for calibrating the voltage ratio of the transformer. The reference IVD was fabricated with the two-stage technique and calibrated by Thompson’s method. The deviation from the nominal ratio of 7.75 was estimated to be $-5.92 \times 10^{\mathrm {-6}}$ for in-phase and $-22.75\times 10^{\mathrm {-6 }}$ for quadrature. The standard uncertainty of this calibration was estimated to be $0.63\times 10^{\mathrm {-6}}$ for in-phase and $6.28\times 10^{\mathrm {-6 }}$ for quadrature.
- Published
- 2015
- Full Text
- View/download PDF
5. Boltzmann Constant Measurements Using QVNS-Based Johnson Noise Thermometry at NMIJ, AIST
- Author
-
Chiharu Urano, Takahiro Yamada, Michitaka Maruyama, Jun Tamba, S. Yoshida, Hirotake Yamamori, Yasuhiro Fukuyama, Kazuaki Yamazawa, N. Kaneko, S. Kiryu, Atsushi Domae, and T. Horie
- Subjects
Physics ,Josephson effect ,Triple point ,Measure (physics) ,Thermodynamics ,Johnson–Nyquist noise ,Thermodynamic temperature ,Condensed Matter Physics ,Metrology ,Computational physics ,symbols.namesake ,Boltzmann constant ,symbols ,NIST - Abstract
Among various methodologies of thermodynamic temperature measurements, Johnson noise thermometry (JNT) has an advantage that the structure and size of the temperature sensing probe are similar to conventional probes for contact thermometry. Another distinguishing feature is that the measurements are all electronic. Furthermore, the application of a quantum voltage noise source (QVNS), first introduced by the National Institute of Standards and Technology (NIST), has improved the accuracy of JNT during the past ten years. These developments have been driven under the rationale to determine the Boltzmann constant $$k$$ , in support of the proposed redefinition of the kelvin, and later to provide practical realization of the kelvin. At NMIJ, AIST, we have been developing a QVNS-based JNT system to first measure the Boltzmann constant and then aim to extend the temperature range to higher temperatures where $$T-T_{90}$$ data are lacking. An impact feature of our system is that most of our key elements have been built independently from NIST and the National Institute of Metrology, China (NIM); in particular that the Josephson junction array has been built in house at NeRI, AIST, and its driving method differs from that of either NIST or NIM. In this paper, the unique elements of the system as well as our initial results on the Boltzmann constant measurements are reported.
- Published
- 2014
- Full Text
- View/download PDF
6. Evaluation of a resistive voltage divider based on a quantized Hall resistance voltage divider
- Author
-
Nobu-Hisa Kaneko, Takehiko Oe, S. Kiryu, and Atsushi Domae
- Subjects
Resistive touchscreen ,Engineering ,business.industry ,Voltage ratio ,020208 electrical & electronic engineering ,Voltage divider ,Electrical engineering ,02 engineering and technology ,01 natural sciences ,Current divider ,Metrology ,010309 optics ,0103 physical sciences ,0202 electrical engineering, electronic engineering, information engineering ,Electronic engineering ,Current (fluid) ,business ,Reference standards - Abstract
The National Metrology Institute of Japan has developed a resistive voltage divider (RVD), which is constructed from a series array of quantized Hall resistance (QHR) bars named “QHR voltage divider (QHR-VD).” In principle, the QHR-VD doesn't need time-consuming bootstrap self-calibration and isn't affected by measurement conditions such as measurement current. Therefore, the QHR-VD is suitable for use as a reference standard for the characteristic evaluation of conventional RVDs. In this paper, evaluation of RVD current dependence based on the QHR-VD is presented. From the measurement results of the RVD current dependence, no current dependence was observed within standard uncertainties.
- Published
- 2016
- Full Text
- View/download PDF
7. Improvement of yield ratio of ohmic contact to GaAs/AlGaAs heterostructure by application of SiO 2 protective layer
- Author
-
K. Matsuhiro, S. Kiryu, Taro Itatani, Nobu-Hisa Kaneko, Takehiko Oe, and Sucheta Gorwadkar
- Subjects
Materials science ,business.industry ,Contact resistance ,Analytical chemistry ,Heterojunction ,Substrate (electronics) ,Quantum Hall effect ,Photoresist ,Condensed Matter Physics ,Corrosion ,Optoelectronics ,business ,Layer (electronics) ,Ohmic contact - Abstract
All the contact pads of a quantized Hall resistance (QHR) device should have a low contact resistance (∼1 Ω) for the application of DC resistance standard devices at cryogenic temperatures. Corrosion of a GaAs/AlGaAs substrate occurs along the edge of the photoresist before the deposition of Ni/AuGe, and we assume that this corrosion degrades the contact resistance. A SiO2 protective layer is effective in preventing the corrosion of and protecting the surface of GaAs/AlGaAs substrate. With the use of this SiO2 protective layer, the yield ratio of the contact resistance to the twodimensional electron gas (2DEG) layer at low temperature (∼0.5 K) and high magnetic field (∼9 T) improves to nearly 100%. (© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
- Published
- 2011
- Full Text
- View/download PDF
8. Development of Quantum Hall Array Resistance Standards at NMIJ
- Author
-
Sucheta Gorwadkar, Nobu-Hisa Kaneko, Takehiko Oe, K. Matsuhiro, Taro Itatani, and S. Kiryu
- Subjects
Engineering ,Condensed matter physics ,Magnetoresistance ,Bar (music) ,business.industry ,Quantum Hall effect ,Plateau (mathematics) ,law.invention ,Metrology ,Gallium arsenide ,chemistry.chemical_compound ,chemistry ,law ,Calibration ,Electrical and Electronic Engineering ,Resistor ,business ,Instrumentation - Abstract
A quantum Hall array resistance standard (QHARS) device with a nominal value close to 10 kΩ on the i = 2 plateau has been developed on a GaAs/AlGaAs heterosubstrate. This QHARS device consists of 266 Hall bar elements, and its nominal value has only 0.0342 × 10-6 difference based on RK-90 ( = 25 812.807 Ω) from an integer value of 104. As a result of comparison measurements with the conventional Quantized Hall Resistance Standard via the 100- Ω standard resistor, the value of the QHARS device agrees with its nominal value within 3.5 × 10-8.
- Published
- 2011
- Full Text
- View/download PDF
9. Design and Fabrication of Integrated Cryogenic Current Comparators
- Author
-
Nobu-Hisa Kaneko, Takehiko Oe, Tetsuro Satoh, Masaaki Maezawa, Chiharu Urano, M. Maruyama, Mutsuo Hidaka, Takahiro Yamada, S. Kiryu, Shuichi Nagasawa, and K. Hinode
- Subjects
Materials science ,business.industry ,Electrical engineering ,Integrated circuit design ,Integrated circuit ,Cryogenics ,Cryocooler ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials ,law.invention ,Cryogenic current comparator ,Metrology ,SQUID ,law ,Electromagnetic coil ,Electrical and Electronic Engineering ,business - Abstract
A cryogenic current comparator (CCC) is an instrument of great importance in electrical metrology, which provides a ratio of two currents with ultimate accuracy based on superconductivity. It is used for dc resistance calibration in many national metrology institutes. Conventional CCCs consist of multi-turn coils of wire windings, a multi-layered shield of superconductor foils and a separate SQUID sensor. This implementation results in a bulky device too massive to cool with a mechanical cryocooler, making a system inconvenient. A new implementation of CCC, an integrated CCC (ICCC) consisting of thin-film spiral coils, a thin-film superconducting shield and a SQUID sensor integrated on a single chip, enables a user-friendly system operated with a compact cryocooler. Prototype ICCC chips were designed and fabricated by using a superconducting Nb integrated circuit technology with chemical-mechanical polishing. The basic operation of the prototype ICCCs was confirmed by monitoring periodic flux-voltage characteristics of the SQUIDs.
- Published
- 2011
- Full Text
- View/download PDF
10. Generation of constant voltage steps by a Josephson array driven by optoelectronically generated pulses
- Author
-
Masaaki Maezawa, Chiharu Urano, Taro Itatani, J. Maeda, S. Kiryu, H. Saitou, Sucheta Gorwadkar, Nobu-Hisa Kaneko, and Takehiko Oe
- Subjects
Cryostat ,Physics ,Josephson effect ,Physics::Instrumentation and Detectors ,business.industry ,Detector ,Energy Engineering and Power Technology ,Photodetector ,Optical power ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials ,Optics ,Fiber laser ,Waveform ,Electrical and Electronic Engineering ,business ,Voltage - Abstract
We observed constant voltage steps for an overdamped Josephson array driven by current pulse trains generated by triggering a photo detector located in a cryostat with a mode locked fiber laser. We measured the voltages of the Josephson array as a function of an optical power. Quantized voltage steps were verified at multiples of about 10 μV which corresponds to the repetition frequency of 50 MHz and the number of junctions of 100. A quantitative analysis was done on the current pulse shape which generated by the MSM detector.
- Published
- 2007
- Full Text
- View/download PDF
11. Operation of Josephson Junctions With Current Pulses Generated by Triggering a Cold Photo Detector With an Optical Comb
- Author
-
J. Maeda, Nobu-Hisa Kaneko, Taro Itatani, Sucheta Gorwadkar, H. Saitou, Chiharu Urano, S. Kiryu, and Masaaki Maezawa
- Subjects
Physics ,Josephson effect ,Cryostat ,Optical fiber ,business.industry ,Detector ,Physics::Optics ,Photodetector ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials ,law.invention ,Optics ,law ,Fiber laser ,Optoelectronics ,Electrical and Electronic Engineering ,Electric current ,business ,Voltage - Abstract
We report the experimental results on a Josephson junction array (JJA) driven by current pulse trains generated by triggering a photo detector located in a cryostat with an optical comb. The key components in the experimental system are a mode locked fiber laser, a metal-semiconductor-metal (MSM) photoconductive switch, and an overdamped JJA. Optical pulse trains generated at room temperature are transmitted via an optical fiber to the MSM-photo detector installed at 4.2 K, and then converted into electric current pulse trains to drive the overdamped JJA. Quantized voltage steps have been verified at multiples of 10 muV, which agrees with the repetition rate of the pulse laser and the number of Josephson junctions in the JJA.
- Published
- 2007
- Full Text
- View/download PDF
12. Observation of Quantized Voltage Steps Using a Josephson Junction Array Driven by Optoelectronically Generated Pulses
- Author
-
Sucheta Gorwadkar, S. Kiryu, Nobu-Hisa Kaneko, J. Maeda, Masaaki Maezawa, H. Saitou, Chiharu Urano, and Taro Itatani
- Subjects
Physics ,Josephson effect ,Optical fiber ,business.industry ,Photodetector ,law.invention ,Pi Josephson junction ,Light source ,law ,Fiber laser ,Optoelectronics ,Electrical and Electronic Engineering ,Optical filter ,business ,Instrumentation ,Voltage - Abstract
In this paper, quantized voltage steps were observed by driving an overdamped Josephson junction array (JJA) with current pulse trains. The current pulse trains were generated by triggering a metal-semiconductor-metal photodetector installed close to JJA at 4.2 K with a mode-locked fiber laser. The intervals of the constant voltage steps were 10 muV, which agrees with the repetition frequency of the light source (49.7 MHz) and the number of Josephson junctions (100) in the JJA. This is the first step toward establishing an ac voltage standard at the National Institute of Advanced Industrial Science and Technology
- Published
- 2007
- Full Text
- View/download PDF
13. Research on voltage ratio for precise comparison between ac QHR and 100-kΩ resistance
- Author
-
Nobu-Hisa Kaneko, S. Kiryu, Atsushi Domae, and Norihiko Sakamoto
- Subjects
Materials science ,business.industry ,Voltage ratio ,Voltage divider ,Electrical engineering ,Voltage source ,Voltage regulator ,Internal resistance ,business ,AC/AC converter - Published
- 2014
- Full Text
- View/download PDF
14. Development of thermodynamic temperature measurement system based on quantum voltage noise source at NMIJ
- Author
-
Yasuhiro Fukuyama, Kazuaki Yamazawa, N. Kaneko, T. Yamamori, Takahiro Yamada, Atsushi Domae, S. Kiryu, Michitaka Maruyama, Chiharu Urano, and S. Yoshida
- Subjects
Physics ,Noise temperature ,Noise generator ,Shot noise ,Thermodynamics ,Y-factor ,Flicker noise ,Johnson–Nyquist noise ,Thermodynamic temperature ,Noise (electronics) ,Computational physics - Published
- 2014
- Full Text
- View/download PDF
15. Linewidth measurement of millimeter wave radiation from a Josephson array source coupled to free space
- Author
-
S. Kiryu and S. Deus
- Subjects
Physics ,Coupling ,Spiral antenna ,Josephson effect ,business.industry ,Astrophysics::Instrumentation and Methods for Astrophysics ,Astrophysics::Cosmology and Extragalactic Astrophysics ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials ,law.invention ,Lens (optics) ,Laser linewidth ,law ,Extremely high frequency ,Optoelectronics ,Array data structure ,Electrical and Electronic Engineering ,business ,Astrophysics::Galaxy Astrophysics ,Gunn diode - Abstract
Radiation from a linear array oscillator with a spiral antenna has been coupled out of the dewar through a Teflon window. Both its linewidth and its power have been measured after coupling the radiation through free space into a second dewar. The linewidth has been determined using a SIS mixer with a spiral antenna which was pumped with an 88 GHz phase-locked Gunn oscillator, and also by Josephson mixing of the array itself. The array oscillator has a distributed array structure of 300 resistively shunted junctions which are placed in groups of 6 junctions. It was fabricated on a silicon wafer and has a two-arm spiral antenna. The chip was attached to a silicon lens with an anti-reflection coating. The linewidth of the array oscillator was determined between 158 GHz and 194 GHz, far below its design frequency of 400 GHz. The measured linewidth and power data of the oscillator reveal interesting information about its phaselocking behavior in the operating range far below its design frequency.
- Published
- 1999
- Full Text
- View/download PDF
16. An interface circuit for a Josephson-CMOS hybrid digital system
- Author
-
Fuminori Hirayama, Toshihiro Sekigawa, Motohiro Suzuki, Akira Shoji, Masahiro Aoyagi, H. Takato, Masaaki Maezawa, S. Kiryu, and Hiroshi Nakagawa
- Subjects
Condensed Matter::Quantum Gases ,Digital electronics ,Josephson effect ,business.industry ,Computer science ,Circuit design ,Electrical engineering ,Mixed-signal integrated circuit ,Hardware_PERFORMANCEANDRELIABILITY ,Integrated circuit ,Condensed Matter Physics ,Circuit extraction ,Computer Science::Other ,Electronic, Optical and Magnetic Materials ,law.invention ,Computer Science::Hardware Architecture ,Computer Science::Emerging Technologies ,CMOS ,law ,Condensed Matter::Superconductivity ,Hardware_INTEGRATEDCIRCUITS ,Electrical and Electronic Engineering ,business ,Hardware_LOGICDESIGN ,Electronic circuit - Abstract
For broadband data communication between Josephson and CMOS digital systems, amplification of small Josephson-output signals and synchronization between the systems are important issues. We present an interface circuit for a Josephson-CMOS hybrid digital system. The interface circuit consists of a parallel-in-parallel-out (PIPO) circuit and built-in Josephson-MOS amplifiers. The PIPO circuit, implemented based on 4JL latching logic technology, performs synchronized data transfer between the Josephson and CMOS circuits. The Josephson-MOS amplifiers consists of stacked Josephson junctions (Suzuki stacks) and MOS inverters which are monolithically integrated on a chip. The circuits have been designed, fabricated and tested. We have successfully confirmed correct operation of the circuits.
- Published
- 1999
- Full Text
- View/download PDF
17. Panic Attacks and Cervical Pain: Outcomes of Traditional and Anti-Oxydative Therapy
- Author
-
D. Labunskiy, N. Kurgaev, N. Kolmykova, V. Podsevatkin, and S. Kiryukhina
- Subjects
Psychiatry ,RC435-571 - Abstract
Introduction Panic attacks(PA) or episodic paroxysmal anxiety are attacks of severe anxiety (panic) or fear (most often - fear of death, less often - fear of losing consciousness, loss of control, helplessness or fear of “going crazy”), accompanied by a rapid heartbeat and a feeling of “suffocation” , “lack of air.” Sometimes there are additional symptoms such as increased blood pressure, a feeling of “internal trembling”, trembling in the limbs, a feeling of “hot flashes” of heat or cold, numbness of the extremities, increased sweating, a feeling of “unstability” or dizziness, nausea, derealization or depersonalization. Objectives It was revealed that many patients with cervical and spinal pain suffer from PA. Psychotherapy and traditional psychopharmacology treatment often not effective. The goal of our study was analysis of radical anti-oxidative therapy for the PA patients in addition to traditional to traditional psychoparmacology and psychotherapy techniques. Methods 12 patients with cervical and 31 with lumbar pain experienced panic attacks during outbreaks of panic attacks. 6 cervical pain patient and 17 patients with lumbar pain were treated by antipsychotic medications also by cognitive behavioral therapy, hypno-suggestive therapy and autogenic training. Other patients also receive hyperbaric oxidation therapy (HBO) in addition to psychopharmacology and psychotherapy. Results It was revealed that patients with PA comorbid with vertebral pathology had much better effects in terms of evading of psychopathologic outcomes. PA became much more rarely and finally disappeared at all. The anti-oxidative treatment was also very beneficial for neurologic symptoms cause by vertebral pain. Conclusions Anti-oxidative therapy showed very marked effect. In this regard, new anti-oxidative treatment seems to be promisable for management of such conditions. Disclosure of Interest None Declared
- Published
- 2023
- Full Text
- View/download PDF
18. Anxiety and Obesity in Children: Anti-oxidative Medications and Hyperbaric Oxigenation Therapy
- Author
-
D. Labunskiy, G. Kukina, M. Kolmykova, and S. Kiryukhina
- Subjects
Psychiatry ,RC435-571 - Abstract
Introduction Obesity is a grave problem in pediatrics and child psychiatry. It was revealed that in many cases obesity has comorbidity with different mental disorders. Besides a number of endocrine disturbances, immune system deficiency and oxidative stress with free radical oxidation take part in pathogenesis of these phenomena. Objectives The essence of the therapeutic effect of hyperbaric oxygen lies in the fact that under the influence of elevated barometric pressure, oxygen saturation of body fluids increases: blood, interstitial fluid, which deliver oxygen to organs and tissues, increasing oxygen supply to cells by 5-10 times and eliminating hypoxia (oxygen starvation tissues). Hyperbaric oxygen, normalizing blood circulation in tissues and metabolic processes at the cellular level, has a number of effects that favorably affect the patient’s condition: promotes the formation of a new vascular network in areas where it is damaged or insufficient, has anti-edematous, anti-inflammatory and wound healing effects, has an immunocorrective effect , normalizes hormonal status, enhances the action of a number of pharmacological agents. The aim of our research was to study effects of HBO on children suffering from anxiety and obesityas a result of the mental instability? S;eep disturbances and immune instability Methods Sessions of hyperbaric oxygenation were carried out at a pressure of 1.6 ATA: the first session lasted 45 minutes, subsequent sessions was 30 minutes. After HBO, each of the patients during the day showed a steady increase in the saturation index, which persisted until the morning of the next day. An analysis of fluctuations in the saturation index during the day showed its decrease in all patients to a minimum value at 8 am and its general dynamic increase from the beginning of hyperbaric oxygenation. Parameters of immune status, including serum concentrations of IgA, IgM and IgG, circulating immune complexes were studied in pediatric patients, aged from 10 to 14 years old, 42 girls and 34 girls. Mapping EEG was used for evaluation of electric brain activity. Results It was found that HBO treatment normalized mental state: patients demonstrated less anxiety and overeating habits, тormalization of sleep, positive dynamics of sleep, reflected in the EEG pattern in the form of alpha waves. Immune reactions were changed: IgA, IgM and IgG, were increased and CIC serum level decreased. Conclusions The use of antioxidant therapy in combination with psychopharmacological drugs has long been a well-established method of treatment for a variety of psychopathological conditions. The inclusion of hyperbaric oxygenation in this complex also helps to achieve more distinct results in terms of weight loss in obesity and normalization of the mental state, improved sleep and significant immunocorrection. Disclosure of Interest None Declared
- Published
- 2023
- Full Text
- View/download PDF
19. Efficiacy of Pharmacotherapy in Patients with Hypothimic Mental Disorders Suffered from Covid-19 Infection
- Author
-
D. Labunskiy, D. Kuzmin, D. Baranov, S. Kiryukhina, and V. Pavelkina
- Subjects
Psychiatry ,RC435-571 - Abstract
Introduction In organic mental disorders in people who have undergone COVID-19, it has been established that the complex use of periciazine in combination with paroxetine, diazepam, 3-hydroxypyridine succinate and hyperbaric oxygenation is superior in effectiveness to traditional therapy with an antipsychotic drug, antidepressant and anxiolytic. The inclusion of 3-hydroxypyridine succinate, hyperbaric oxygenation in the complex therapy of this pathology corrects the concentrations of adrenaline, norepinephrine, dopamine, serotonin in the peripheral blood of patients, eliminates hormonal status disorders and humoral immune responses. Objectives The aim of the work was to optimize approaches to the treatment of hypothymic disorders in organic mental illness, to substantiate the complex use of periciazine in combination with paroxetine, diazepam, 3-hydroxypyridine succinate and hyperbaric oxygenation in patients who underwent COVID-19. Methods The object of the clinical study were patients with organic mental disorders who underwent COVID-19. To assess the condition, laboratory research methods were selected taking into account the etio- and pathogenesis of diseases: determining the level of catecholamines, some indicators of humoral immune responses, and the hormonal profile. Results Table 2.3 - Nosological structure of patients included in the study Nosological form Associated hypothymic disorder Number of patients Gender Average age (years) Males Females Organic mental disorder Organic anxiety disorder F06.4 21 15 6 28,7±6,3 Depressive Episode F33 22 12 9 Organic mental disorder associated with COVID-19 Organic anxiety disorder F06.4 18 15 3 Depressive Episode F33 16 10 6 43,7±7,4 Conclusions In patients with organic mental disorders, occurring with hypothymic symptoms, compared with healthy donors, there is a complex of disorders in plasma concentrations of catecholamines. Traditional and, to a greater extent, combination therapy increase the levels of serotonin, dopamine, norepinephrine, both in the group of patients who did not have COVID-19, and in those who underwent a new coronovirus infection. In patients with organic mental disorders, occurring with hypothymic symptoms, compared with healthy donors, there is a complex of disorders in plasma concentrations of catecholamines. Traditional and, to a greater extent, combination therapy increase the levels of serotonin, dopamine, norepinephrine, both in the group of patients who did not have COVID-19, and in those who underwent a new coronovirus infection.Complex therapy with periciazine, paroxetine, diazepam in combination with 3-hydroxypyridine succinate and HBO for organic mental disorders causes a more complete reduction of hypothymic disorders both in the group of patients who did not have COVID-19, and in those who underwent a new coronovirus infection. Disclosure of Interest None Declared
- Published
- 2023
- Full Text
- View/download PDF
20. Off-chip detection of radiation from a linear array oscillator with a spiral antenna
- Author
-
S. Kiryu, S. Deus, James E. Lukens, Wenxing Zhang, and Siyuan Han
- Subjects
Spiral antenna ,Physics ,business.industry ,Bolometer ,Radiation ,Condensed Matter Physics ,Chip ,Electronic, Optical and Magnetic Materials ,law.invention ,Lens (optics) ,law ,Array data structure ,Optoelectronics ,Wafer ,Electrical and Electronic Engineering ,business ,Voltage - Abstract
Radiation from a linear array oscillator with a spiral antenna has been measured using an off-chip coupled bolometer. The array oscillator has a distributed array structure with 300 resistively shunted junctions which are placed in the groups of 6 junctions. The array oscillator was fabricated on a Si wafer with a two-arm spiral antenna. The chip was attached to a Si lens with an anti-reflection coating. Rather large power (>100 nW) was detected at a number of array bias voltages V/sub bias/ from 115 mV to 196 mV, which correspond from 185 GHz to 315 GHz. The maximum measured power was 550 nW at V/sub bias/=125 mV (200 GHz).
- Published
- 1997
- Full Text
- View/download PDF
21. New design of the quantized Hall resistance array device
- Author
-
Taro Itatani, Nobu-Hisa Kaneko, Takehiko Oe, S. Kiryu, and Sucheta Gorwadkar
- Subjects
Engineering ,Distance measurement ,business.industry ,Bar (music) ,Electrical engineering ,Calibration ,Measurement uncertainty ,Ranging ,business ,Metrology - Abstract
National Metrology Institute of Japan have been proposed and fabricated the quantized Hall resistance (QHR) array devices, and confirmed the performance with uncertainty of as low as 10−8. The new combinations of Hall bars have been designed ranging from 100 Ω to 1 MΩ. This new combinations realize the quantized resistance values more closely to decade values with fewer numbers of Hall bars. In the new design, 10-kΩ QHR array device consists of only 16 Hall bars, and this number is about 16 times lower than that in the previous design however the nominal value is same to previous one. This fact might allow us to evaluate each Hall bar in the array device.
- Published
- 2012
- Full Text
- View/download PDF
22. Evaluation of a voltage divider based on quantized Hall resistance arrays
- Author
-
K. Matsuhiro, Atsushi Domae, Nobu-Hisa Kaneko, Takehiko Oe, and S. Kiryu
- Subjects
Physics ,Condensed matter physics ,Voltage ratio ,law ,Voltage divider ,Resistor ,Current divider ,Temperature measurement ,Magnetic field ,law.invention - Abstract
A one-chip quantized voltage divider device based on integrated quantized Hall resistance (QHR) technology has been developed. A QHR voltage divider device that consists of a series of thirty-two quantized Hall bars has been fabricated. The dependence of the Hall resistance R H on the magnetic flux density showed that the device will function as a voltage divider. From the preliminary test of the 1∶1 voltage ratio evaluation, the deviation from the nominal voltage ratio of 1∶1 was estimated to be less than ± 10 × 10−6.
- Published
- 2012
- Full Text
- View/download PDF
23. DC-SQUID system with flexible pickup coil connected by a novel superconducting technique
- Author
-
Norio Chiba, S. Kiryu, Nobuhiro Shimizu, Kazuo Chinone, Naoko Kasai, and Satoshi Nakayama
- Subjects
Superconductivity ,Josephson effect ,Quantitative Biology::Biomolecules ,Materials science ,business.industry ,Superconducting magnet ,Condensed Matter Physics ,Noise (electronics) ,Electrical connection ,Electronic, Optical and Magnetic Materials ,Nuclear magnetic resonance ,Electromagnetic coil ,Condensed Matter::Superconductivity ,Beta (plasma physics) ,Optoelectronics ,Pickup ,Electrical and Electronic Engineering ,business - Abstract
A reliable and compact bonding method for superconductively connecting input coils to pickup coils has been developed using a low-temperature flip-chip bonding technique which does not cause the deterioration of Josephson junctions. Axial first-order gradient pickup coils made of a flexible sheet were fabricated and tested to investigate their mass producibility. The system noise of a single-channel system with a flexible pickup coil, with 17-mm coil diameter and 60-mm baseline, connected by a superconductive flip-chip bonding technique, was about 20 fT/ square root Hz using a large beta L DC-SQUID (superconducting quantum interference device). >
- Published
- 1993
- Full Text
- View/download PDF
24. Performance of DC SQUIDs fabricated on 4-inch silicon wafer
- Author
-
Kazuo Chinone, Norio Chiba, Nobuhiro Shimizu, S. Yabe, T. Ishikawa, and S. Kiryu
- Subjects
Superconductivity ,Josephson effect ,Washer ,Materials science ,business.industry ,Niobium ,chemistry.chemical_element ,Sputter deposition ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials ,law.invention ,SQUID ,chemistry ,law ,Etching (microfabrication) ,Optoelectronics ,Wafer ,Electrical and Electronic Engineering ,business - Abstract
A Nb/AlO/sub x//Nb Josephson process has been developed to fabricate DC superconducting quantum interference devices (SQUIDs) for biomagnetic measurements on 4-in silicon wafers. The purpose of the process is to fabricate high-quality junctions and to keep the quality uniform over a silicon wafer. All the films were deposited using magnetron sputtering. The components of the SQUID, except the junctions, were formed by taper etching to improve the step coverage. The uniformity of the SQUID characteristics (critical current, modulation depth, and mutual inductance between SQUID and modulation coil) was measured, and an excellent value of less than +or-5% was obtained. Three different configurations of SQUIDs, single washer (SW), double washer series (DWS), double washer parallel (DWP) have been fabricated with the same characteristics. The SW (single washer) had a white noise level of 6.3*10/sup -6/ Phi /sub 0// square root Hz, lower than those of DWS and DWP. 1/f crossover frequencies were below 1 Hz. >
- Published
- 1993
- Full Text
- View/download PDF
25. Effect of RF interference on characteristics of DC SQUID system
- Author
-
N. Kasai, S. Kiryu, H. Sato, K. Nagata, and N. Ishikawa
- Subjects
Superconductivity ,Physics ,Squid ,biology ,business.industry ,Magnetometer ,Condensed Matter Physics ,Gradiometer ,Electromagnetic interference ,Electronic, Optical and Magnetic Materials ,Magnetic field ,law.invention ,Nuclear magnetic resonance ,law ,Condensed Matter::Superconductivity ,biology.animal ,Optoelectronics ,Electrical and Electronic Engineering ,business ,Noise (radio) ,Voltage - Abstract
The effects of RF interference on the characteristics of DC superconducting quantum interference devices (SQUIDs) are investigated. The noise of a DC SQUID gradiometer radiating an RF field with a frequency between 100 kHz and 80 MHz was measured. As the RF field strength intensified, the white noise level increased and the cut-off frequency was lowered. The flux-voltage transfer function (dV/d Phi ) of the DC SQUID was influenced strongly by the RF field. dV/d Phi decreased as the RF field intensified. Based on these results, the level of the electromagnetic environment at which the operation of the SQUID system would not be affected was found. The effect of high-frequency magnetic field on the flux to voltage transfer function was investigated by computer simulation using a simple resistively shunted junction (RSJ) model. >
- Published
- 1993
- Full Text
- View/download PDF
26. Thermal magnetic noise of Dewars for biomagnetic measurements
- Author
-
K. Sasaki, N. Kasai, Y. Suzuki, and S. Kiryu
- Subjects
Cryostat ,Materials science ,Condensed matter physics ,Magnetometer ,Astrophysics::Instrumentation and Methods for Astrophysics ,General Physics and Astronomy ,Cryogenics ,Space (mathematics) ,Biomagnetism ,law.invention ,Conductor ,Physics::Fluid Dynamics ,Nuclear magnetic resonance ,law ,Thermal ,General Materials Science ,Electrical conductor - Abstract
The thermal magnetic noise of three Dewars with different structures was measured using a d.c. SQUID magnetometer and the contributions from the metallic conductors in the bottom and in the side vacuum spaces were estimated. It is concluded that the axial component of the thermal magnetic noise of a Dewar is mainly caused by the conductors in the bottom space and the magnitude of thermal noise is determined by the total amount of conductor.
- Published
- 1993
- Full Text
- View/download PDF
27. Effects of parasitic capacitance in a magnetically-coupled voltage multiplier
- Author
-
Fuminori Hirayama, Akira Shoji, S. Kiryu, Hitoshi Sasaki, and Masaaki Maezawa
- Subjects
Materials science ,Differential capacitance ,Ground ,business.industry ,Condensed Matter Physics ,Capacitance ,Inductive coupling ,Electronic, Optical and Magnetic Materials ,law.invention ,SQUID ,Parasitic capacitance ,law ,Optoelectronics ,Voltage multiplier ,Electrical and Electronic Engineering ,business ,Voltage - Abstract
Effects of parasitic capacitance in a magnetically-coupled voltage multiplier (VM) are described. We found that parasitic capacitance between SQUIDs and JTLs in a VM decreases its operating margin. We also found that separation of electric grounds for the output terminal of a VM from those for the JTLs is effective to improve the operating margin. Using this method, a 64-stage VM was fabricated and well-defined output voltage was obtained.
- Published
- 2001
- Full Text
- View/download PDF
28. Development of 10 KΩ quantum Hall array resistance standards at NMIJ
- Author
-
Hiroyuki Ishii, Chiharu Urano, H. Fujino, Masaaki Maezawa, K. Matsuhiro, S. Kiryu, G. Sucheta, Nobu-Hisa Kaneko, Takehiko Oe, and Taro Itatani
- Subjects
Physics ,business.industry ,Bar (music) ,Contact resistance ,Electrical engineering ,Quantum Hall effect ,Plateau (mathematics) ,Gallium arsenide ,Magnetic field ,chemistry.chemical_compound ,chemistry ,Optoelectronics ,Development (differential geometry) ,business ,Gaas algaas - Abstract
An experimental device of quantum Hall array resistance standards (QHARS) with a nominal value close to 10 kΩ on the i = 2 plateau have been developed on a GaAs/AlGaAs hetero-substrate. This device consists of just 266 Hall bar elements that are connected by triple connection technique. Its nominal value has only 0.034 2 ppm differences from the integer value of 104. This array device clearly shows the well-quantized 10 kΩ plateau (i=2).
- Published
- 2010
- Full Text
- View/download PDF
29. Development of on-chip double-shielded quantum Hall device for use in ac quantized Hall resistance measurement
- Author
-
Chiharu Urano, G. Sucheta, Masaaki Maezawa, Atsushi Domae, H. Fujino, Taro Itatani, Nobu-Hisa Kaneko, Takehiko Oe, S. Kiryu, K. Matsuhiro, and Hiroyuki Ishii
- Subjects
Engineering ,Hardware_MEMORYSTRUCTURES ,Physics::Instrumentation and Detectors ,business.industry ,Electrical engineering ,Shields ,Hardware_PERFORMANCEANDRELIABILITY ,Quantum Hall effect ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,Computer Science::Hardware Architecture ,Hall effect ,Hardware_INTEGRATEDCIRCUITS ,System on a chip ,Hall effect sensor ,Integrated circuit packaging ,Chip carrier ,business ,Electrical impedance - Abstract
We have developed a on-chip double-shielded quantum Hall device and a double-shielded chip-carrier. The device in conjunction with the carrier will realize impedance standard based on the quantum Hall effect. In this configuration, the Hall bar is covered by separated on-chip shields and shields of the chip carrier to retrieve the leakage current. In this paper, we show detail of the QHR device fabrication and the structure of the chip carrier.
- Published
- 2010
- Full Text
- View/download PDF
30. Directly-coupled DC-SQUID magnetometers made of Bi-Sr-Ca-Cu oxide films
- Author
-
Y. Murayama, M. Matsuda, S. Kiryu, Shinya Kuriki, T. Endo, Masao Koyanagi, Satoshi Kashiwaya, and N. Kasai
- Subjects
Materials science ,High-temperature superconductivity ,Magnetometer ,Analytical chemistry ,Oxide ,Flux ,Noise (electronics) ,Magnetic flux ,Electronic, Optical and Magnetic Materials ,law.invention ,Loop (topology) ,SQUID ,chemistry.chemical_compound ,Nuclear magnetic resonance ,chemistry ,law ,Electrical and Electronic Engineering - Abstract
High-T/sub c/ DC-SQUID magnetometers made of Bi-Sr-Ca-Cu oxide films were designed and fabricated. A directly coupled scheme where a SQUID loop and a pick-up loop are connected directly in parallel was chosen to avoid fabricating the multilayered structure. The flux noise, which was measured in FLL (flux locked loop) operation at 4.2 K, increased in a form of 1/f as the frequency decreased below 20 Hz. The level of white noise at the frequency range above 20 Hz was about 1*10/sup -4/ Phi /sub 0// square root Hz, corresponding to the field resolution of 1.5 pT/ square root Hz at the pickup loop.
- Published
- 1991
- Full Text
- View/download PDF
31. Josephson junction array driven by modulated optical combs
- Author
-
N. Kaneko, S. Kiryu, Chiharu Urano, Taro Itatani, and Masaaki Maezawa
- Subjects
Generator (circuit theory) ,Physics ,Josephson effect ,Interferometry ,Optics ,Modulation ,business.industry ,Fiber laser ,Physics::Optics ,business ,Pulse-width modulation ,Voltage ,Pulse (physics) - Abstract
We have performed an experiment to drive an over-damped Josephson junction array (JJA) with modulated current pulse trains, which are generated by a modulated optical comb (an ultra-short pulse laser). The intensities of optical pulse trains are modulated using a pulse pattern generator. We quantitatively verified that the output voltages of the JJA were consistent with the modulation signals.
- Published
- 2008
- Full Text
- View/download PDF
32. Development of a voltage divider based on quantized Hall resistance arrays for a high DC voltage standard II
- Author
-
Atsushi Domae, H. Ishii, Nobu-Hisa Kaneko, Taro Itatani, Takehiko Oe, Chiharu Urano, and S. Kiryu
- Subjects
Materials science ,business.industry ,Voltage divider ,Electrical engineering ,Heterojunction ,Hardware_PERFORMANCEANDRELIABILITY ,Quantum Hall effect ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,Current divider ,law.invention ,Metrology ,law ,Hardware_INTEGRATEDCIRCUITS ,Voltage multiplier ,Resistor ,business ,Voltage - Abstract
A one-chip quantized voltage divider device based on the technology of integration of quantized Hall resistance (QHR) bars on a GaAs/AlGaAs Heterostructure Substrate has been developed. The first experimental QHR voltage divider device, which consists of a series of 20 QHR bars, has been fabricated. A preliminary test in our evaluation study of the device clearly shows that it functions as a voltage multiplier/divider.
- Published
- 2008
- Full Text
- View/download PDF
33. Feasibility study of on-chip class E DC-DC converter
- Author
-
S. Kiryu, Marian K. Kazimierczuk, and Tadashi Suetsugu
- Subjects
Physics ,Forward converter ,Voltage-controlled oscillator ,Low-dropout regulator ,Flyback converter ,Boost converter ,Hardware_INTEGRATEDCIRCUITS ,Ćuk converter ,Charge pump ,Electronic engineering ,Hardware_PERFORMANCEANDRELIABILITY ,Inductor - Abstract
A 200 mW, 800 MHz class E DC-DC converter is designed using a 0.6 /spl mu/m CMOS process and then simulated. A 22 nH spiral inductor is used in the resonant circuit. An integrated feedback controller with a VCO is used for the output voltage regulation. It is shown that the class E inverter is an excellent candidate for on-chip switching converters because of very high efficiency, and the inductor can be minimized at high operating frequencies. The simulated converter efficiency was 72% at 4.5 V output voltage, 200 mW output power, and 800 MHz switching frequency.
- Published
- 2003
- Full Text
- View/download PDF
34. Ultrasonic imaging by fractal dimension of power spectrum shape
- Author
-
S. Kiryu, T. Kikuchi, and S. Sato
- Subjects
Physics ,Optics ,Fractal ,business.industry ,Mathematical analysis ,Spectrum (functional analysis) ,Probability distribution ,Spectral density ,Point (geometry) ,Ultrasonic sensor ,business ,Fractal analysis ,Fractal dimension - Abstract
A new method for imaging the random media by analyzing power spectrum shapes using fractal dimensions is presented. It may be possible to estimate the structural characteristics from the spectrum, because the ultrasonic power spectrum shapes may be affected by the statistical distributions of the point scatterers in the random media. Fractal theory is adapted to estimate the power spectrum shapes. The fractal dimension is used for characterization of the complexities of the power spectrum shape because it indicates the complexity or roughness of figures. The relations of mean spacing vs. fractal dimension and irregularity vs. fractal dimension obtained by numerical calculations are given. An experiment for ultrasonic imaging by mapping the fractal dimension is described. >
- Published
- 2002
- Full Text
- View/download PDF
35. Evaluation of ac-dc difference of thermal converters using an SFQ-based D/A converter
- Author
-
Akira Shoji, Masaaki Maezawa, Hitoshi Sasaki, Fuminori Hirayama, S. Kiryu, and V. Bubanja
- Subjects
Thermal converter ,Physics ,Josephson effect ,business.industry ,Ćuk converter ,Electrical engineering ,Converters ,Electromagnetic heating ,Metrology ,Electronic engineering ,Waveform ,Electrical and Electronic Engineering ,business ,Instrumentation ,Voltage - Abstract
Digital-to-analog (D/A) converters based on the Josephson effect are promising for ac voltage standards because they produce voltage steps with ultimate precision and stability. We are currently developing a single-flux-quantum (SFQ)-based D/A converter, designed for synthesizing sinusoidal waveforms for metrological applications. In this paper, we examine feasibility of an ac-dc transfer difference measurement for a thermal converter using the SFQ-based D/A converter.
- Published
- 2002
- Full Text
- View/download PDF
36. Dynamics of Psychopathological Disorders and Changes in the Functional Activity of Neutrophils in Mercury Intoxication
- Author
-
D. Labunskiy, V. Podsevatkin, S. Kiryukhina, and N. Kolmykova
- Subjects
Psychiatry ,RC435-571 - Abstract
Introduction The overall goal was to determine the degree of mental, neuromuscular and statodynamic functions disorders resulting from toxic effect of mercury and its compounds, to study relationship between the degree of loss of professional ability to work as a result of occupational disease with the presence of complications due to concomitant diseases. Objectives The relevance of studying the degree of violations of the main indicators of vital activity due to the toxic effect of mercury and its compounds is due to the persisting high level of loss of professional ability to work, and in some cases, and disability of this contingent. Analysis of indicators of primary and repeated disability due to occupational diseases showed that a sufficiently high number of persons recognized as disabledю Methods We studied the dynamics of psychopathological disorders: violation of the emotional sphere, thinking, perception, attention, volitional activity and cognitive functions. The functional and metabolic activity of segmented neutrophils in the peripheral blood of 42 patients, men and women aged 43 to 64 years, and 22 healthy donors were studied. Results Long-term exposure to chronic industrial mercury intoxication led to persistent disorders of mental functions, suppression of phagocytic activity of neutrophils up to 42.3+-4.7 per cent and inhibition of the reaction with nitro blue cytosol 4.2+-0.1 per cent.. Conclusions The revealed violations of the emotional-volitional sphere and cognitive mental functions are possibly associated with the suppression of nonspecific cellular reactions of microphages. Violations of neuroimmune interactions in mercury intoxication require further study. Disclosure No significant relationships.
- Published
- 2022
- Full Text
- View/download PDF
37. Dimethylarginine dimethylaminohydrolase (DDAH) as a nerve-injury-associated molecule: mRNA localization in the rat brain and its coincident up-regulation with neuronal NO synthase (nNOS) in axotomized motoneurons
- Author
-
S, Nakagomi, S, Kiryu-Seo, M, Kimoto, P C, Emson, and H, Kiyama
- Subjects
Male ,Motor Neurons ,Hypoglossal Nerve Injuries ,Hydrolases ,Brain ,Axotomy ,Wounds, Penetrating ,Nitric Oxide Synthase Type I ,Amidohydrolases ,Rats ,Animals ,Tissue Distribution ,RNA, Messenger ,Nitric Oxide Synthase ,Rats, Wistar - Abstract
As part of a project to identify genes up-regulated by injury of the motor neuron, a clone encoding dimethylarginine dimethylaminohydrolase (DDAH) was isolated. This enzyme is known to metabolize methylarginines, which are endogenous inhibitors of NOS activity. DDAH may therefore contribute to the control of NO synthesis. The present study demonstrated that both DDAH and nNOS mRNAs are up-regulated after axotomy in injured hypoglossal motor neurons. The profile of DDAH mRNA up-regulation in the injured hypoglossal motor neurons paralleled that of NADPH diaphorase staining. While the expression of both DDAH and nNOS was upregulated in motor neurons following nerve injury, the normal distribution of DDAH and nNOS mRNAs in the noninjured central nervous system were distinctly different. We speculate that both genes are involved in the upregulation of NO production following nerve transection, although the role of NO in the process of nerve regeneration is so far unknown.
- Published
- 1999
38. Action of 1,1-Dimethyl-4-(Phenylsulfonyl) Semicarbazide (DPSS), A New Antisenescence Preservative for Cut Carnation Flowers
- Author
-
Shigeru Satoh, S. Kiryu, Naoki Midoh, Toshihito Yoshioka, and M. Mikami
- Subjects
Preservative ,Semicarbazide ,biology ,Chemistry ,fungi ,food and beverages ,Environmental pollution ,Carnation ,biology.organism_classification ,Acute toxicity ,Ames test ,Horticulture ,Silver thiosulfate ,chemistry.chemical_compound ,Biochemistry - Abstract
Increasing flower’s longevity by blockage of the onset of senescence has economical importance. Currently, STS (silver thiosulfate complex anion), is being used as an anti-senescence preservative in the cut-flower industry. But, STS contains a heavy metal ion (Ag+) and has a potential environmental hazard. Therefore, it is desired to have alternatives to STS, which are safe for organisms and have a less risk for environmental pollution. DPSS is a novel preservative for cut carnation flowers, which were developed recently [1] and has just come to the market in Japan. Its activity to retard carnation flower senescence is compatible to or more than that of STS. DPSS is safe for organisms including mammals, because its oral and dermal administration causes no acute toxicity in mice and exerts no mutagenic effects by Ames test.
- Published
- 1999
- Full Text
- View/download PDF
39. Development of a one-chip quantized Hall resistance voltage divider
- Author
-
K. Matsuhiro, Atsushi Domae, Nobu-Hisa Kaneko, Takehiko Oe, and S. Kiryu
- Subjects
Physics ,Resistive touchscreen ,business.industry ,Applied Mathematics ,Voltage divider ,Electrical engineering ,Chip ,Current divider ,Magnetic field ,Development (differential geometry) ,Voltage source ,business ,Instrumentation ,Engineering (miscellaneous) ,Voltage - Abstract
A resistive voltage divider, which is constructed from a binary segmented series array of quantized Hall resistance (QHR) bars fabricated on one chip, named the ?QHR voltage divider?, has been developed. The QHR voltage divider does not, in principle, require time-consuming bootstrap self-calibration and will provide voltage ratios that are defined by fundamental physical constants with small uncertainties. To evaluate the performance of the QHR voltage divider, the dependence of the Hall resistances RH?of all serial segments on the magnetic flux density was measured. The results of the RH?measurement showed large and well-defined plateaus, and it was confirmed that the fabricated QHR divider in conjunction with a suitable voltage source would function as a voltage divider. From a preliminary test of the voltage ratios of the QHR voltage divider, deviations from nominal ratios were measured to be less than 1.4???10?6, and the expanded uncertainty of the measurement was estimated to be less than 4.1???10?6.
- Published
- 2012
- Full Text
- View/download PDF
40. Utilization of a cryo-prober system for operation of a pulse-driven josephson junction array
- Author
-
Nobu-Hisa Kaneko, Chiharu Urano, H. Yamamori, Akira Shoji, Y Hashimoto, Michitaka Maruyama, Mutsuo Hidaka, Shuichi Nagasawa, Masaaki Maezawa, Tetsuro Satoh, S. Kiryu, and H. Suzuki
- Subjects
Josephson effect ,Capacitive coupling ,History ,Engineering ,business.industry ,Electrical engineering ,Chip ,Computer Science Applications ,Education ,Rapid single flux quantum ,Chip carrier ,Wideband ,business ,Voltage ,Electronic circuit - Abstract
We demonstrated the operation of pulse-driven Josephson junction arrays (JJAs) for AC voltage standard using a wideband cryo-prober system with a 4-K Gifford-MacMahon (GM) cooler. This unique system was originally developed for high-speed network switch applications of rapid-single-flux-quantum (RSFQ) circuits and enables wideband data transmission at bit rates of higher than 10 Gbps between room-temperature and cryogenic environments. JJA chips were fabricated using NbN-based superconductor-normal metal-superconductor (SNS) junctions. A 5-mm chip was mounted on a 16-mm chip carrier using flip-chip bonding technology for probe contact. To obtain bipolar output voltages, we tried two types of testing based on the AC coupling technique proposed by the National Institute of Standards and Technology (NIST). A pulse pattern generator (PPG) with a large memory of 134 Mbit was used for covering a wide frequency range of output signals. As a result, we succeeded in bipolar operation of the JJA, generating waveforms at frequencies from 60 Hz to several tens of kilo hertz. The maximum rms voltage obtained for a single array was 12.7 mV. The observed spurious level was lower than -93 dBc at 16 kHz.
- Published
- 2010
- Full Text
- View/download PDF
41. A new coding technique in serial data transmission and demodulation with Josephson junctions array
- Author
-
Shuichi Nagasawa, Akira Shoji, N Kaneko, Mutsuo Hidaka, Masaaki Maezawa, Chiharu Urano, H. Yamamori, S. Kiryu, Tetsuro Satoh, M Maruyama, Y Hashimoto, and H. Suzuki
- Subjects
Josephson effect ,History ,Optical fiber ,Materials science ,business.industry ,Electrical engineering ,Cryocooler ,Multiplexer ,Computer Science Applications ,Education ,law.invention ,Photodiode ,Duty cycle ,law ,Pulse wave ,Demodulation ,Optoelectronics ,business - Abstract
We have developed a coding technique to drive an overdamped Josephson junction array (JJA) using modulated optical pulses for voltage standard applications. Our system is composed of a multi-channel pulse pattern generator (PPG), a LiNbO3 (LN) modulator with an electrical multiplexer (MUX), a photodiode (PD), and an over-damped JJA cooled with 4 K GM cryocooler. The modulated optical pulses are transmitted via an optical fiber to a PD that is installed close to the JJA on a cold stage, and they are then converted into an electrical current pulse train in order to drive the JJA. To avoid a problem in our LN modulator system, i.e., the duty-ratio dependence of the output pulse waveform, pseudo signals that maintain the duty ratio at approximately 50% are inserted in the original bit stream. We demonstraited that this technique is applicable for arbitrary return-to-zero (RZ) binary bit streams.
- Published
- 2010
- Full Text
- View/download PDF
42. Pulse driven Josephson voltage standard using modulated optical comb
- Author
-
Masaaki Maezawa, Chiharu Urano, Taro Itatani, S. Kiryu, and N Kaneko
- Subjects
Josephson effect ,Physics ,History ,business.industry ,Josephson voltage standard ,Electrical engineering ,Biasing ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,Computer Science Applications ,Education ,Pulse (physics) ,Pi Josephson junction ,Optical modulator ,Modulation ,Condensed Matter::Superconductivity ,Optoelectronics ,business ,Voltage - Abstract
We have performed an experiment to drive an overdamped superconductor-insulator-normal-insulator-superconductor (SINIS) Josephson junction array (JJA) with modulated current pulse trains, which are generated by modulated ultra short optical pulses. Averaged voltage outputs of the JJA have been systematically measured for various modulation patterns as a function of the bias voltage of an optical modulator. Quantized voltage steps has been clearly observed in accordance with modulation patterns under certain condition of the bias voltage of the optical modulator.
- Published
- 2008
- Full Text
- View/download PDF
43. Hyperbaric oxygenation of autoimmune manifestation in coversational disorders
- Author
-
D. Labunskiy, S. Kiryukhina, V. Podsevatkin, E. Govsh, and V. Kolmyykov
- Subjects
Conversional Disorders ,Hyperbaric Oxygenaations ,Immunoglobulins ,Psychiatry ,RC435-571 - Abstract
Introduction Study of conversion disorders is urgent problem in psychiatry due to high prevalence of hysterical manifestations, both in structure of various mental diseases and in general somatic network: among population it is from 0.5 to 2%. Objectives Our aim was to study the effect of complex therapy, combining traditional psychopharmacological drugs and hyperbaric oxygenation, on indicators of acid-base balance of blood, neurotransmitter metabolism, immune and hormonal status in experimental modeling of stress, as well as reduction of psychopathological symptoms in various forms of hysterical disorders. Methods Studies were conducted with the participation of 160 patients (145 women and 15 men), average age 33.5 ± 6.1 years, Сontent of adrenaline, norepinephrine, dopamine, serotonin was determined by concentration of prolactin, thyroid-stimulating hormone (TSH), free thyroxine (T4 light), cortisol using ELISA. Immune status was assessed according to following indicators: determination of level of immunoglobulins of classes A, M and G by the method of radial immunodiffusion in a gel; study of total complementary activity of blood serum by hemolytic method. Results It is necessary to highlight a significant increase in the concentration of Ig G and Ig A, a higher level of large, medium and small circulating immune complexes, which does not exclude the development of autoimmune reactions as a result of a long course of the mental process, which occurs with damage to the own cells of the nervous tissue. Conclusions Кevealed changes in the immune and endocrine reactions upon admission, under the influence of HBO treatment indicate involvement of these structures in the pathogenetic mechanisms. Disclosure No significant relationships.
- Published
- 2021
- Full Text
- View/download PDF
44. Risk factors of arteriosclerosis in Japanese children
- Author
-
K. Yamauchi, M. Okuni, K. Hayashi, and S. Kiryu
- Subjects
Male ,Risk ,medicine.medical_specialty ,Adolescent ,Physiology ,Serum total cholesterol level ,Hypercholesterolemia ,education ,Myocardial Infarction ,Coronary Disease ,chemistry.chemical_compound ,Sex Factors ,Japan ,Internal medicine ,medicine ,Humans ,Obesity ,Myocardial infarction ,Child ,Health Education ,Triglycerides ,Cholesterol ,business.industry ,Age Factors ,Arteriosclerosis ,medicine.disease ,Elevated total cholesterol ,Health Surveys ,Coronary heart disease ,chemistry ,Physical therapy ,Female ,lipids (amino acids, peptides, and proteins) ,Health education ,Lipoproteins, HDL ,Cardiology and Cardiovascular Medicine ,business - Abstract
Total cholesterol level was measured in 8,303 children and youth in Tokyo. Age ranged from 6 to 18 years. The change of total cholesterol level relates to sex and age, and girls showed higher level than boys. Not a small number of children revealed elevated total cholesterol level but some children showed very low level. HDL-cholesterol was determined and prevalence of ischemic coronary heart disease risk factors was studied. The elevation of total cholesterol level in senior high school students was caused by either increase of HDL-cholesterol or increased total minus HDL-cholesterol fraction. High school boys with obesity were found to have higher serum total cholesterol level accompanied by low HDL-cholesterol level. High school boys of parents with myocardial infarction were found to have higher total cholesterol level. Majority of Japanese senior high school students were found to have one or more coronary heart disease risk factors. The necessity of prevention for ischemic coronary heart disease starting from childhood in Japan is emphasized.
- Published
- 1980
- Full Text
- View/download PDF
45. The crystal and molecular structure of 1,10-dithia-[2.2]metacyclophane
- Author
-
W. Nowacki and S. Kiryu
- Subjects
Crystal ,Inorganic Chemistry ,Crystallography ,Materials science ,Molecule ,General Materials Science ,Condensed Matter Physics - Abstract
The crystal structure of 1,10-dithia-[2.2]metacyclophane, C14H12S2, has been determined by x-ray diffraction methods. The crystals are monoelinic with space group P21/n and cell dimensions a = 7.868, b = 27.269, c = 5.600 Å and β = 98.17°; Z = 4. The structure was solved by direct methods and refined by block-diagonal least-squares methods; R = 0.036 for the 1425 observed reflections. The molecule was found to be highly strained and the boat-shape deformation of both phenyl rings was observed.
- Published
- 1975
- Full Text
- View/download PDF
46. The crystal and molecular structure of 8 -nitro-1,10 -dithia- [2.2 ] metacyclophane
- Author
-
S. Kiryu and W . Nowacki
- Subjects
Inorganic Chemistry ,Crystal ,Crystallography ,Chemistry ,Nitro ,Molecule ,General Materials Science ,Condensed Matter Physics - Published
- 1975
- Full Text
- View/download PDF
47. The crystal structure of nickel(II)-dehydroacetic acid monoimide complex
- Author
-
S. Kiryu
- Subjects
Nickel ,chemistry.chemical_compound ,Chemistry ,Polymer chemistry ,General Earth and Planetary Sciences ,chemistry.chemical_element ,Crystal structure ,Dehydroacetic acid ,General Environmental Science - Published
- 1967
- Full Text
- View/download PDF
48. In vitro release characteristics of diclofenac and hydrocortisone from Pluronic F-127 gels
- Author
-
H, Tomida, M, Shinohara, N, Kuwada, and S, Kiryu
- Subjects
Diclofenac ,Ointment Bases ,Hydrocortisone ,Chemistry, Pharmaceutical ,Poloxalene ,Gels ,Polyethylene Glycols - Published
- 1987
49. [Protein binding of nonsteroidal anti-inflammatory agents. II. Effects of various drugs on protein binding of salicylic acid (author's transl)]
- Author
-
Y, Kaneo, A, Nishikawa, Y, Kato, and S, Kiryu
- Subjects
Sulfonamides ,Anti-Inflammatory Agents ,Drug Interactions ,Serum Albumin, Bovine ,Salicylates ,Protein Binding - Published
- 1978
50. [Effect of complex formation on interfacial transfer rate of drugs across two liquid phases (author's transl)]
- Author
-
S, Kiryu, T, Tateyama, and S, Iguchi
- Subjects
Barbital ,Barbiturates ,Water ,Benzene ,Biological Transport ,Aminopyrine ,Models, Biological - Published
- 1982
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.