1. High resolution 3D dosimetry for microbeam radiation therapy using optical CT
- Author
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Ciara M. McErlean, Simon J. Doran, Martin O. Leach, John Adamovics, Elke Bräuer-Krisch, Inst Canc Res, CRUK Canc Imaging Ctr, London SW3 6JB, England, European Synchrotron Radiation Facility (ESRF), Heuris Pharma LLC, Skillman, NJ 08558 USA, Rider University, Royal Marsden NHS Trust, Clin Magnet Resonance Res Grp, London, England, and Univ Surrey, Dept Phys, Guildford GU2 5XH, Surrey, England
- Subjects
History ,Materials science ,Dosimeter ,medicine.diagnostic_test ,010308 nuclear & particles physics ,business.industry ,[SDV]Life Sciences [q-bio] ,High resolution ,Computed tomography ,01 natural sciences ,030218 nuclear medicine & medical imaging ,3. Good health ,Computer Science Applications ,Education ,03 medical and health sciences ,0302 clinical medicine ,3d dosimetry ,Microbeam radiation therapy ,0103 physical sciences ,Optical ct ,medicine ,Dosimetry ,Irradiation ,Nuclear medicine ,business - Abstract
International audience; Optical Computed Tomography (CT) is a promising technique for dosimetry of Microbeam Radiation Therapy (MRT), providing high resolution 3D dose maps. Here different MRT irradiation geometries are visualised showing the potential of Optical CT as a tool for future MRT trials. The Peak-to-Valley dose ratio (PVDR) is calculated to be 7 at a depth of 3mm in the radiochromic dosimeter PRESAGE (R). This is significantly lower than predicted values and possible reasons for this are discussed
- Published
- 2015
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