High resolution 3D dosimetry for microbeam radiation therapy using optical CT

Authors :: Ciara M. McErlean
Simon J. Doran
Martin O. Leach
John Adamovics
Elke Bräuer-Krisch
Inst Canc Res, CRUK Canc Imaging Ctr, London SW3 6JB, England
European Synchrotron Radiation Facility (ESRF)
Heuris Pharma LLC, Skillman, NJ 08558 USA
Rider University
Royal Marsden NHS Trust, Clin Magnet Resonance Res Grp, London, England
Univ Surrey, Dept Phys, Guildford GU2 5XH, Surrey, England
Source :: 'Journal of Physics : Conference Series ', vol: 573, pages: 012032-1-012032-4 (2015), 8th International Conference on 3D Radiation Dosimetry (IC3DDose), 8th International Conference on 3D Radiation Dosimetry (IC3DDose), Sep 2014, Ystad, Sweden. 4 p., ⟨10.1088/1742-6596/573/1/012032⟩
Publication Year :: 2015
Publisher :: IOP Publishing, 2015.
Abstract: International audience; Optical Computed Tomography (CT) is a promising technique for dosimetry of Microbeam Radiation Therapy (MRT), providing high resolution 3D dose maps. Here different MRT irradiation geometries are visualised showing the potential of Optical CT as a tool for future MRT trials. The Peak-to-Valley dose ratio (PVDR) is calculated to be 7 at a depth of 3mm in the radiochromic dosimeter PRESAGE (R). This is significantly lower than predicted values and possible reasons for this are discussed