Search

Transcatheter aortic valve implantation (TAVI) is becoming the standard of care for severe symptomatic aortic stenosis (AS). Yet, some patients with AS are not indicated/eligible for TAVI. Several noninvasive, catheter-based or surgical alternatives exist, and other therapeutic options are emerging. This review provides an overview of non-TAVI options for severe AS. Non-invasive, transcatheter, and alternative surgical strategies are discussed, emphasizing their backgrounds, techniques, and outcomes. Alternative therapies to TAVI, whether device-based or non-device-based, continue to evolve or emerge and provide either alternative treatments or a bridge to TAVI, for patients not meeting indications for, or having contraindications to TAVI. Although TAVI and SAVR are the current dominant therapies, there are still some patients that could benefit in the future from other alternatives. Data on alternative options for such patients are scarce. Many advantages and disadvantages arise when selecting a specific treatment strategy for individual patients. Head-to-head comparison studies could guide physicians toward better patient selection and procedural planning. Awareness of therapeutic options, indications, techniques, and outcomes should enable heart teams to achieve optimized patient selection. Furthermore, it can increase the use of these alternatives to optimize the management of AS among different patient populations. [ABSTRACT FROM AUTHOR]

This special issue is devoted to highlighting thinkers who have been overlooked within business ethics and who have important contributions to make to our field. We make the case that, as scholars of a hybrid discipline that also aims to address important issues of business practice, we need to look continually for new sources of insight and wisdom that can both enrich our discourse and improve our ability to generate ideas that have a positive impact on business practice. In this introductory essay, we discuss our rationale for creating this special issue, summarize the articles contained within, and close with thoughts on its significance for the field going forward. [ABSTRACT FROM AUTHOR]

Sea ice fraction (SIF) over the Ross/Amundsen/Bellingshausen Sea (RAB) are investigated using the Modern-Era Retrospective Analysis for Research and Application, Version 2 (MERRA-2), focusing on the differences in time-lagged response to ENSO between the late 20th (1980–2000, L20) and the early 21st century (2001–2021, E21). The findings suggest that the typical Antarctic response to ENSO is influenced by changes in ENSO type/intensity, highlighting the need for caution when investigating the Antarctic teleconnection. Time-lagged regressions onto the mature phase of El Niño reveal that the SIF decrease and SST increase over the RAB is relatively weaker in E21 and most pronounced at 0–4 months lag. Conversely, the SIF in L20 continues to decline and reaches its peak at two-season lag (5–7 months). Tropospheric wind, pressure, and wave activity in response to El Niño in L20 show a zonally oriented high/low-pressure areas with two-season lag, enhancing the poleward flow that plays a key role in sea ice melt in the RAB, while this pattern in E21 is insignificant at the same lag. This study suggests that stronger (weaker) and more eastern (central) Pacific ENSOs on average in L20 (E21) are associated with this decadal change in the SIF response to ENSO. [ABSTRACT FROM AUTHOR]

Pulmonary autograft, or Ross procedure, is performed by supplanting a diseased aortic valve with the patient's own pulmonary valve. Reconstruction of the right ventricular outflow tract is then completed using a pulmonary homograft. To our knowledge, infective endocarditis occurring decades after the Ross procedure has not been reported. Diligent echocardiographic examination can be crucial to ensure prompt treatment and avoid the 25% mortality rate associated with infective endocarditis. Clinical suspicion should remain high in those with a pulmonary autograft history. In this article, we report the case of a 39-year-old patient with infective endocarditis presenting 22 years after Ross procedure.

ObjectiveOne of the goals of the poultry industry is to select animals that increased growth rates and also muscle mass while maintaining meat quality. The present study was conducted to evaluate performance, some meat quality characteristics, and gene expression associated with growth (IGF-I, IGF-II, TGF-β1, Myostatin) in three strains of Arian, Ross, and Cobb.Materials and methodsTo do this research 150 one-day-old (male and female) broiler chicks of Arian, Ross, and Cobb strains were categorized in a completely randomized design with three treatments, five replicates, and 10 observations per replicate. The function, some physical characteristics of meat, and the relative expression of their genes were investigated. Strain types had a significant effect on the feed conversion ratio (FCR).ResultsIn the whole the rearing period, the lowest FCR was for the Ross strain and the highest was for the Cobb strain. TPA test of the breast showed that hardness, cohesiveness, and chewiness in Arian, Ross, and Cobb strains were significantly different. Maximum hardness and chewiness were for the Arian and Cobb strains and maximum cohesiveness was for the Ross strain. There were no significant differences between strains for adhesiveness, springiness, or gumminess. TPA test of the thigh showed that hardness, chewiness, and gumminess were not significantly different, but cohesiveness, adhesiveness, and springiness were significantly different between strains. Maximum cohesiveness and springiness were observed in the Arian strain and maximum adhesiveness was for the Ross strain. Breast and thigh pressure tests of the three strains showed that hardness and deformation of hardness were not significantly different. IGF-I and IGF-II relative gene expression of breast meat had no significant difference between strains. TGF-β1 and myostatin relative gene expression were significantly different and the Cobb strain had the highest relative gene expression of TGF-β1. Also, IGF-I and IGF-II relative gene expression had no significant difference in the liver.ConclusionsGiven the individual advantages of each strain in some traits, more research is needed with specialized diets for each strain to be able to comment conclusively on the superiority of their traits.

Early modern ballads supplied tools for managing information, allowing audiences to compare stories, handle variants and sort through multiple interpretations. These activities revised how and what people learn when they come together, a transformation of social life similarly explored in Macbeth, where this technology takes shape in the messenger Ross. Ross dispenses information but also disrupts and sometimes shuts down lines of communication, connecting courts with battlefields, inventorying the dead and preparing bodies for slaughter. Drawing on scholarship about ballad reception, cognitive ecology and Shakespearean surveillance, I consider Ross's communications within a larger early modern social world which deactivates its members. [ABSTRACT FROM AUTHOR]

Sea ice fraction (SIF) over the Ross/Amundsen/Bellingshausen Sea (RAB) are investigated using the Modern-Era Retrospective Analysis for Research and Application, Version 2 (MERRA-2), focusing on the differences in time-lagged response to ENSO between the late 20th (1980–2000, L20) and the early 21st century (2001–2021, E21). The findings suggest that the typical Antarctic response to ENSO is influenced by changes in ENSO type/intensity, highlighting the need for caution when investigating the Antarctic teleconnection. Time-lagged regressions onto the mature phase of El Niño reveal that the SIF decrease and SST increase over the RAB is relatively weaker in E21 and most pronounced at 0–4 months lag. Conversely, the SIF in L20 continues to decline and reaches its peak at two-season lag (5–7 months). Tropospheric wind, pressure, and wave activity in response to El Niño in L20 show a zonally oriented high/low-pressure areas with two-season lag, enhancing the poleward flow that plays a key role in sea ice melt in the RAB, while this pattern in E21 is insignificant at the same lag. This study suggests that stronger (weaker) and more eastern (central) Pacific ENSOs on average in L20 (E21) are associated with this decadal change in the SIF response to ENSO.

This search includes (180 male and 180 female) from the three generations (G) grandparent, (P) parent, and (B) broiler generations of commercial chicken (Ross). Blood samples were collected in 3 ml tubes with EDTA, genomic DNA extracted by Promega's Wizard Genomic DNA Purification Kit. The Nano Drop® spectrophotometer has been used to analyze DNA purity and concentration and it’s varied from (1.7 to 1.9). RAPD-PCR was performed using 18 primers from the GenScript USA Series (Table 1). The reaction mixture are 25 μl made up the PCR reaction. An initial phase of DNA denaturation at 94°C for 5 minutes was followed by 40 cycles of DNA denaturation at 94°C for 1 minute, annealing as described with each primer, extension at 72°C for 1 minute, and final extension at 72°C for 5 minutes. Electrophoresis on 2% agarose gels in 1x TBE buffer (Promega, USA). A UV transi was used to see the amplified pattern. The OPA-07 Primer produced the most bands (73) bands among all generations used. All of the Primers combined to generate a total of (442) bands, and there were 48 bands that were polymorphic. The primer OPQ-12 had the highest percentage of polymorphisms, (23.53), Primer OPA-07 has the widest molecular weight range (100-1500 bp). The highest genetic similarity is observed 0.813 between (P♀) and (B♂).The dendrogram consists of two clusters, one of which includes (B♀, P♀, B♂) and the other includes (G♂, G♀, P♂), where it is clear that the genetic distance is very high between (G♀ and P♀), while it is less between (B♂ and P♀) and also between (G♂ and G♀) while the distance is intermediate between (B♂ and B♀) and also between (G♂ and P♂). The goal of the current study was to use RAPD-PCR to determine the genetic distance and genetic relationship between generations of chickens.

Abstract Background The ideal conduit for repair of the right ventricular outflow tract (RVOT) during the Ross procedure remains unclear and has yet to be fully elucidated. We perform a pairwise meta-analysis to compare the short-term and long-term outcomes of decellularized versus cryopreserved pulmonary allografts for RVOT reconstruction during the Ross procedure. Main body After a comprehensive literature search, studies comparing decellularized and cryopreserved allografts for patients undergoing RVOT reconstruction during the Ross procedure were pooled to perform a pairwise meta-analysis using the random-effects model. Primary outcomes were early mortality and follow-up allograft dysfunction. Secondary outcomes were reintervention rates and follow-up endocarditis. A total of 4 studies including 1687 patients undergoing RVOT reconstruction during the Ross procedure were included. A total of 812 patients received a decellularized pulmonary allograft, while 875 received a cryopreserved pulmonary allograft. Compared to cryopreserved allografts, the decellularized group showed similar rates of early mortality (odds ratio, 0.55, 95% confidence interval, 0.21–1.41, P = 0.22). At a mean follow-up period of 5.89 years, no significant difference was observed between the two groups for follow-up allograft dysfunction (hazard ratio, 0.65, 95% confidence interval, 0.20–2.14, P = 0.48). Similarly, no difference was seen in reintervention rates (hazard ratio, 0.54, 95% confidence interval, 0.09–3.12, P = 0.49) nor endocarditis (hazard ratio, 0.30, 95% confidence interval, 0.07–1.35, P = 0.12) at a mean follow-up of 4.85 and 5.75 years, respectively. Conclusions Decellularized and cryopreserved pulmonary allografts are associated with similar postoperative outcomes for RVOT reconstruction during the Ross procedure. Larger propensity-matched and randomized control trials are necessary to elucidate the efficacy of decellularized allografts compared to cryopreserved allografts in the setting of the Ross.

Objective: One of the goals of the poultry industry is to select animals that increased growth rates and also muscle mass while maintaining meat quality. The present study was conducted to evaluate performance, some meat quality characteristics, and gene expression associated with growth (IGF-I, IGF-II, TGF-β1, Myostatin) in three strains of Arian, Ross, and Cobb. Materials and methods: To do this research 150 one-day-old (male and female) broiler chicks of Arian, Ross, and Cobb strains were categorized in a completely randomized design with three treatments, five replicates, and 10 observations per replicate. The function, some physical characteristics of meat, and the relative expression of their genes were investigated. Strain types had a significant effect on the feed conversion ratio (FCR). Results: In the whole the rearing period, the lowest FCR was for the Ross strain and the highest was for the Cobb strain. TPA test of the breast showed that hardness, cohesiveness, and chewiness in Arian, Ross, and Cobb strains were significantly different. Maximum hardness and chewiness were for the Arian and Cobb strains and maximum cohesiveness was for the Ross strain. There were no significant differences between strains for adhesiveness, springiness, or gumminess. TPA test of the thigh showed that hardness, chewiness, and gumminess were not significantly different, but cohesiveness, adhesiveness, and springiness were significantly different between strains. Maximum cohesiveness and springiness were observed in the Arian strain and maximum adhesiveness was for the Ross strain. Breast and thigh pressure tests of the three strains showed that hardness and deformation of hardness were not significantly different. IGF-I and IGF-II relative gene expression of breast meat had no significant difference between strains. TGF-β1 and myostatin relative gene expression were significantly different and the Cobb strain had the highest relative gene expression of TGF-β1. Also, IGF-I and IGF-II relative gene expression had no significant difference in the liver. Conclusions: Given the individual advantages of each strain in some traits, more research is needed with specialized diets for each strain to be able to comment conclusively on the superiority of their traits. [ABSTRACT FROM AUTHOR]

Background : At present, the majority of aortic valve diseases have been traditionally treated by prosthetic valve replacement, whether using a mechanical or a bio-prosthetic valve. Surgical management of aortic valve disease in pediatric patients is still a great challenge, especially the surgical timing, selection of surgical approach, and optimal surgical materials. Aim of Review : In this paper, the main perspective is to propose the use of an aortic stent coating with endothelial cells and smooth muscle cells on both sides as aortic valve in the Ozaki procedure. Owing to its good biocompatibility, stability, thin but high tensile strength, anti-calcification, anticoagulant properties, and rapid endothelialization in vivo, long-term results from that instead of autologous pericardium in the Ozaki procedure may be superior to Ross in pediatric patients. Key Scientific Concepts of Review : The key scientific concepts are as follows: (1) a one-step, rapid, and robust concept for the preparation of aortic stent coating with endothelial cells and smooth muscle cells, and (2) Ozaki procedure. • In this paper, the main perspective is to propose the use of an aortic stent vessel sheet coating with endothelial cells and smooth muscle cells on both sides as an aortic valve, which is superior to the autologous pericardial, as well as its non-calcification properties, based on good hemodynamics, high docking points, and sufficient docking area of the Ozaki procedure. • Avoiding long-term anticoagulation and infection by the rapid endothelialization. Thereby realizing the long-term durability after reconstruction, or elimination of the possibility of a reoperation and long-term anticoagulation. • Reoperation should not be seen as an absolute failure in patients who undergo the Ozaki procedure, the focus should be on restoring normal life expectancy and quality of life. [ABSTRACT FROM AUTHOR]

Copyright of Computer Measurement & Control is the property of Magazine Agency of Computer Measurement & Control and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Canadian Journal of Anaesthesia / Journal Canadien d'Anesthésie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Sammendrag Denne artikkelen gir en kort historisk oversikt over den nordiske rettspragmatismens utvikling og søker å gi en karakteristikk av de sentrale elementer i rettspragmatismen.

Objective The aim of this study was to compare the quality characteristics of retorted Samgyetang (Korean ginseng chicken soup) made from white semi-broilers (WSB; Ross× Hyline white, 3 weeks old), commercial broilers (CB; Ross, 4 weeks old), Korean native chickens (KNC; Hanhyup-3-ho, 12 weeks old) and old laying hens (OLH; Hyline white, 72 weeks old) and to explore the possibility of using the carcasses of KNCs and OLHs as raw material for product diversification. Methods Raw and cooked meat quality, fatty acid composition and consumer acceptance were analyzed. Results Among the chicken breeds, OLH and KNC showed a higher shear force value than WSB and CB due to high insoluble collagen contents. However, the meat of KNC was more tender than that of OLH. The meat of OLH was characterized by the lowest moisture content and highest crude fat content. The meat of KNC was characterized by a higher proportion of saturated fatty acids, α-linolenic acid and arachidonic acid than that of OLH. The meat of OLH showed the highest content of unsaturated fatty acid, particularly linoleic acid, in its thigh meat. Electronic nose readings revealed that the meat aroma pattern was clearly different across breeds. OLH had the lowest overall acceptance score, while no differences were found in flavor, texture, juiciness and appearance among WSB, CB, and KNC. Conclusion KNC shows potential as raw material for Samgyetang, while additional preprocessing methods, such as tenderization and fat removal, are required for the utilization of OLH as raw material for retorted Samgyetang.

Background: The ideal conduit for repair of the right ventricular outflow tract (RVOT) during the Ross procedure remains unclear and has yet to be fully elucidated. We perform a pairwise meta-analysis to compare the short-term and long-term outcomes of decellularized versus cryopreserved pulmonary allografts for RVOT reconstruction during the Ross procedure. Main body: After a comprehensive literature search, studies comparing decellularized and cryopreserved allografts for patients undergoing RVOT reconstruction during the Ross procedure were pooled to perform a pairwise meta-analysis using the random-effects model. Primary outcomes were early mortality and follow-up allograft dysfunction. Secondary outcomes were reintervention rates and follow-up endocarditis. A total of 4 studies including 1687 patients undergoing RVOT reconstruction during the Ross procedure were included. A total of 812 patients received a decellularized pulmonary allograft, while 875 received a cryopreserved pulmonary allograft. Compared to cryopreserved allografts, the decellularized group showed similar rates of early mortality (odds ratio, 0.55, 95% confidence interval, 0.21–1.41, P = 0.22). At a mean follow-up period of 5.89 years, no significant difference was observed between the two groups for follow-up allograft dysfunction (hazard ratio, 0.65, 95% confidence interval, 0.20–2.14, P = 0.48). Similarly, no difference was seen in reintervention rates (hazard ratio, 0.54, 95% confidence interval, 0.09–3.12, P = 0.49) nor endocarditis (hazard ratio, 0.30, 95% confidence interval, 0.07–1.35, P = 0.12) at a mean follow-up of 4.85 and 5.75 years, respectively. Conclusions: Decellularized and cryopreserved pulmonary allografts are associated with similar postoperative outcomes for RVOT reconstruction during the Ross procedure. Larger propensity-matched and randomized control trials are necessary to elucidate the efficacy of decellularized allografts compared to cryopreserved allografts in the setting of the Ross. [ABSTRACT FROM AUTHOR]

Abstract Background A 34-year-old gentleman presented with Staphylococcus salivarius infective endocarditis 13 years after aortic homograft and mitral valve repair for degenerative bicuspid aortic valve associated with rheumatic heart disease. The homograft had calcified, and the mitral repair had deteriorated with severe regurgitation. Multidisciplinary team decision to restore best quality of life was for re-do Ross procedure with bi-leaflet preserving mitral valve replacement with an inverted RESILIA aortic valve as the patient was fundamentally against lifelong anti-coagulation. Case presentation The aortic homograft was excised, and coronary arteries dissected out followed by harvesting of the pulmonary autograft. The mitral valve was accessed via a trans-septal approach. On examination, there was a restricted and thickened posterior mitral valve leaflet. An inverted 27-mm INSPIRIS RESILIA aortic bio-prosthesis was placed with mitral cusps preserved. The pulmonary autograft was implanted in an intra-annular position, and a 26-mm pulmonary homograft was used to replace the pulmonary valve. Echocardiogram at 4 weeks revealed preserved LV function and well-functioning prosthetic, autograft and homograft. Conclusion An inverted RESILIA valve, with its anti-structural valve deterioration properties, can be used in the mitral position with preservation of the mitral cusps to avoid anti-coagulation with the hope of reducing need for re-operation in line with patient wishes.

Antibiotics that permeate aquatic environments present significant risks to both ecosystems and human health. In this study, we employed the techniques of room temperature aqueous solution precipitation to fabricate ZIF-67 derivatives, and established a Co 3 O 4 /CeO 2 /O 3 /PMS (Co-Ce/OP) system. Furthermore, a 10 mg/L Levofloxacin (LEF) solution could reach rapid degradation (97.2%) and effective mineralization (40.4%) under specific conditions. Subsequent investigations identified the primary active substances, intermediates, and reaction mechanism in the Co-Ce/OP system. Evidence from Electron Paramagnetic Resonance (EPR) and quenching experiments indicates that SO 4 ·-, OH·, O 2 ·- and 1O 2 contribute to the degradation process. Applying High Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS), we discovered that the principal degradation mechanisms for LEF encompass the cleavage and subsequent loss of the piperazine, quinolone, and morpholine rings, in addition to decarboxylation and defluorination reactions. Besides, we studied the acute toxicity, bioconcentration factor, developmental toxicity, and mutagenicity of LEF and its intermediate products. Our findings reveal a notable reduction in the toxicity of the intermediate products relative to LEF. Later experiment demonstrates that the degradation rate of LEF sustains above 90% after five cycles of reactions, indicative that the catalyst has excellent recyclability and stability. Furthermore, this study employed experiments across four different natural water matrices, demonstrating the system's considerable potential for effective application within authentic aquatic settings. [Display omitted] • Co 3 O 4 /CeO 2 was fabricated by combination of precipitation and calcination strategy. • The Co 3 O 4 /CeO 2 /O 3 /PMS system exhibited excellent catalytic activity and stability. • OH·, SO 4 ·-, O 2 ·-, and 1O 2 were involved in the reaction process. • Proposed the degradation pathways of LEF and the eco-toxicity of the intermediates. [ABSTRACT FROM AUTHOR]

Esta traducción al español corresponde a la intervención oral del Profesor Enrico Berti en el Istituto Italiano per gli Studi Filosofici el 13 junio de 2017. Berti es profesor emérito de la Universidad de Padua, con ocasión de la publicación de su traducción de la Metafísica de Aristóteles en el 2017, en el encuentro de estudio La metafísica de Aristóteles, en el Instituto de Estudios Filosóficos de Nápoles. Considero que al hacerlo se contribuye a la divulgación de esta nueva traducción entre la comunidad hispanohablante.

The objective of this study was to estimated gene expression in breast muscles of two broiler strains with used to Myoustatin gene in marketing age (5 weeks of age) under heat stress and compared to control group for 1 hour daily for 7 days in Shalakan farm of Faculty of Agriculture, Ain Shams University, broiler chicks (150 chicks in each strains) of 1 day of age were used in this study. So, the measurements were taken (respiratory rate, rectal temperature and estimated gene expression). The results obtained the gene expression of Myostatin gene in muscle breast was observed highest in Ross strain compared with Indian River strain under heat stress, but no different between strains ( Ross and Indian River) in control group. However, respiratory rate of Ross and Indian River under heat at 5 week of age showed that the Indian River strain was high significant at 5 week of age compared to Ross ones. As shown that rectal temperature of Ross and Indian River were a high significant effect of treatment (heat group was higher from control group) and not a significant of strain.The present experiment was conducted to estimated gene expression on meat quality traits of different tropical stress conditions in different broiler strains during 7 days and 5 weeks of age. Introgressions some major genes likes myostatin gene in muscle breast into broiler improve under the heat stress.

In recent decades, more and more research has been done worldwide on the use of biostimulating products as dietary factors to increase weight gain and improve feed conversion to broiler chickens, as well as to preserve their condition. health and obtaining high quality carcasses. In this paper we aim to analyze the productive performance of the Ross-308 hybrid. The biological material was represented by 100 commercial hybrids of ROSS-308 hens. The birds were divided into 2 batches of 50 individuals each (LM-control batch and LA-batch where the "Esstence" biostimulator was administered) and reared according to the specific technology. species, from the age of one day and up to 42 days. During the research, one of the morphological indicators followed was body weight, and at the end of the week, the daily feed gain was calculated. Other indicators followed were the average daily consumption and the food conversion ratio. Finally, the data were statistically processed using the Anova (Analysis of variance) program. At the middle of the experiment (end of the 3rd week) the first batch (LM) had an average weight of 975.2g and the 2nd batch analyzed (LA), at this point in life exceeded the threshold of 1 kg, having an average body weight of 1119.3 g. After the first week of life, the chicks in the control batch (LM) achieved an average daily gain of 21.73 g / head / day. The birds in this series had a total increase (42 days), an increase of 54.91 g / head / day. For the second batch (LA), the results were slightly better. Thus, the weight gain started from a value of 23.87 g / head / day (after the first 7 days), the average for this parameter being 63.60 g / head / day. At the end of the experiment, the average of the first batch was higher compared to that obtained in the second batch (LM> LA) 1.66 kg c.f./kg increase> 1.22 kg c.f./kg increase. The final conclusion of our study is that the use of a good quality biological material, ensuring optimal microclimate conditions and good quality food, but also the administration of biostimulators helps to achieve good performance in growing Ross-308 hybrids for the production of meat. [ABSTRACT FROM AUTHOR]

Meat processing involves several successive transformations, the first consisting in obtaining the carcass, and the second ensures the separation of the carcass from by-products (bones, skin, feathers), the meat being used in the manufacture of the products. In this paper we aim to analyze the quantitative meat production obtained from the chicken broiler Ross-308 The biological material was 100 commercial hybrids of ROSS-308 chicken. The birds were reared according to the species-specific technology, and the actual determinations were performed on 20 individuals (10 males and 10 females) who were slaughtered at the age of 42 days. During the research, one of the indicators followed was the live weight, by weighing the flock of birds, using an electronic scale. After slaughter, the poultry carcasses were weighed fresht, but also after refrigeration (24h at 4°C). With the data provided, the slaughter yield and the share of participation in the carcass composition of the cut portions were calculated. The data were statistically processed using the Anova (Analysis of variance) program. After weighing the studied males, an average weight of 2622.98 g was found, and in females, the average recorded weight was 2480.04 g. and 76.67% on refrigerated carcasses). In the case of females, slightly lower values were obtained, of 74.28% for the cold yield and 75.68% for the hot yield; recorded the best performance in the thighs (21%) and in the chest (24%). Females had higher values in the case of back, which occupied about 49% of the total carcass. In both sexes, the wings had a participation rate of about 9%. Due to the qualities that poultry broiler meat presents, there is a growing demand for this type of meat on the world market, therefore, such research is of continuous interest. The rearing of the Ross-308 broiler in an intensive system has wide development perspectives, if an optimal technology is used, but also a good quality biological material. [ABSTRACT FROM AUTHOR]

The uncontrolled introduction of micropollutants to the environment has caused huge concern globally owing to their hazardous effects. Although conventional advanced oxidation processes are fruitful to stimulate peroxymonosulfate (PMS) and peroxydisulfate (PDS) to produce reactive oxygen species (ROSs) and eradication of hazardous materials, their high operational cost and leaching of metal ions have opened another chapter of pollution in the form of heavy metals in the environment. Therefore, low-cost, and highly efficient degradation techniques are most urgently required to prevent the large-scale accumulation of hazardous materials in the environment. In this review, we have discussed in detail the photocatalytic stimulation of PMS and PDS for the initiation of ROSs to oxidize highly toxic environmental pollutants. Some highly efficient carbonaceous photocatalysts and supportive materials including g-C 3 N 4 , multi walled carbon nanotubes, graphene, and graphene oxide are discussed owing to their supreme charge conductivity and large surface area to present huge number of active sites and assist the stimulation of PMS and PDS. Further, we have discussed the role of different metal organic frameworks in the stimulation of PMS and PDS for pollutants eradication. Detailed degradation mechanisms of many pollutants are provided to support the generation of different ROSs working in the eradication of the target substances. Finally, a future perspective has been discussed for the incoming researchers to cope with environmental issues properly. [Display omitted] • Photocatalytic activation of peroxymonosulfate (PMS) and peroxydisulfate (PDS) has been chalked out to produce ROSs. • The activation mechanisms of sulfate, PMS and PDS are discussed in detail. • The role of different carbonaceous materials and MOFs in the activation of PMS and PDS has been been explored. • Pollutants degradation mechanisms have been discussed in detail. [ABSTRACT FROM AUTHOR]

• Fluorescein molecules are extensively utilized to develop fluorescent probes for different analytes due to their unique and excellent photophysical properties and spirocyclic structural feature. • This article overview different strategies for the development of fluorescent sensors, operating through the modification of skeletons of fluorescein. • This review article summarised synthetic methodology, sensing mechanism and unique features of fluorescein based fluorescent probes developed over last decade. The quantification and sensing of biologically and environmentally relevant ions and molecules have been active and emergent research area in domain of molecular recognition and sensing by tailored molecular sensors and probes. In the designing of efficient molecular sensor, fluorescein dye are highly demandable because of their interesting photophysical properties, water solubility and biocompatibility. Additionally, unique structure features of fluorescein dye like phenolic and carboxylic groups along and different active sites available in structure for suitable substituents make it exciting scaffolds for designing of molecular sensor. This feature review article provides a special emphasis on different strategies in the designing of fluorescent molecular probes that are operating through functionalization of fluorescein skeletons which are developed since the year 2014 for sensing of biologically important cations, anions and small molecules. In addition, we have discussed the synthesis, characterization, fluorescent behaviour, and binding mechanism of some selected fluorescein based molecular sensors. [ABSTRACT FROM AUTHOR]

El libro Legalidad de Scott Shapiro se propone llevar a cabo una estimulante, pero ardua, tarea filosófica, a saber: ofrecer una explicación de aquello que el derecho es y de por qué vale la pena tenerlo. Su “Teoría del derecho como plan” aborda la primera cuestión en términos de la denominada tesis de los “hechos sociales” y la segunda en términos de la tesis del “fin moral”. Así, el derecho está determinado únicamente por hechos sociales, pero posee un punto moral, puesto que la finalidad de la actividad legal es solucionar algunos problemas morales. Las escuelas filosófico-jurídicas del siglo veinte se han dividido acerca de estos temas. Entre tales escuelas, Shapiro rechaza la visión realista porque deja de lado el punto de vista interno. Sin embargo, muchas afirmaciones realistas se referían al conocimiento del derecho, no a su normatividad. El artículo aborda este punto recordando también el debate entre Hart y Ross.

Objective: The Ross operation is a widely accepted option for aortic valve replacement in children, and evidence shows its excellent results in terms of hemodynamics and durability. However, indications are still limited due to the fact that it is a technically demanding procedure, only performed by specialized surgeons. On top of that, and despite numerous techniques being applied, autograft dilatation remains a key disadvantage, which can lead to graft failure. In recent years, the ExoVasc Personalized External Aortic Root Support (PEARS) has proven to be a safe and effective option to prevent aortic root dilatation in various aortopathies and is a technique that lends itself to support the pulmonary autograft in the Ross operation., Methods: During the past 7 years, we have used the ExoVasc PEARS graft, manufactured from the patients' pulmonary artery measurements from computed tomography scan data, to support the pulmonary autograft in the Ross operation. This graft (manufactured by Exstent Ltd, UK) is implanted at the same time as the autograft. We have reviewed all the patients who underwent this surgery, including demographic data, aorta measurements, operative data, and follow-up assessment consisting of periodic echocardiograms and magnetic resonance imaging scans., Results: Fifty patients were included in the study. Mean age at the time of the operation was 29.84 years, the youngest patient was 9 years-old. Nineteen patients (38%) had previous sternotomies; 11 of them having had a previous aortic valve replacement. Seventy-two percent of patients had initially a bicuspid aortic valve. Mean diameter of the ascending aorta was 3.83 cm. Forty-four percent of patients required a concomitant reduction aortoplasty due to mismatch sizes between the ascending aorta and the autograft. Mean bypass and crossclamp times were 200.66 and 151.14 minutes, respectively. Median length of stay was 6 days. Mean follow-up was 16.88 months. Two patients required subsequent aortic valve replacement (1 had rheumatic valve disease and the other had iatrogenic damage in his autograft valve leaflet). Ascending aorta dimensions remain stable when compared with immediate postoperative studies. There were no deaths., Conclusions: The ExoVasc PEARS graft has proven to be an excellent support in the Ross operation to prevent the autograft failure related to autograft dilatation that can offer several advantages compared with other existing techniques. With this type of support, we believe the Ross indications can be expanded to multiple clinical scenarios, given the good long-term results this operation offers in terms of durability, life expectancy, and hemodynamics., Competing Interests: The authors reported no conflicts of interest. The Journal policy requires editors and reviewers to disclose conflicts of interest and to decline handling manuscripts for which they may have a conflict of interest. The editors and reviewers of this article have no conflicts of interest., (© 2024 The Author(s).)

The porous graphitic carbon nitride nanosheets (PCNSs) with high yields were synthesized by using one–step chemical exfoliation method. PCNSs accelerated separation efficiency of photo-generated electron−hole pairs in comparison to bulk graphitic carbon nitride. The PCNS5 (exfoliation for 5 h) exhibited optimal photocatalytic disinfection capability towards Escherichia coli K-12 under simulated solar light irradiation with complete disinfection of 6.5 log 10 cfu/mL of E. coil K-12 within 2 h. The enhanced photocatalytic activity of PCNS5 originated from mesoporous nanosheet structure. The possible mechanism of photocatalytic disinfection has proposed that intracellular reactive oxygen species levels and the activities of antioxidant enzymes (e.g., catalase and superoxide dismutase) were enhanced. Transmission electron microscope images observed during photocatalytic disinfection process suggested that the cell membrane was regarded as the first target for oxidation, resulting in a faster leakage of cytoplasmic content and finally degradation of DNA leading to bacterial death. Furthermore, the trapping experiment showed that superoxide radical (•O 2 −) and holes (h+) were responsible for E. coli K-12 disinfection by PCNS5. Image 1 • The PCNS5 has a high photocatalytic disinfection efficiency of E. coil K-12. • Combined effect of photogenerated and intracellular ROSs was key for disinfection. • Intracellular ROSs levels was remarkably enhanced by photo-generated ROSs. • Leaks of intracellular components and DNA damage were observed in E. coil K-12. [ABSTRACT FROM AUTHOR]

Graphical abstract Highlights • As(III) was oxidized in the presence of CSF and O 2. • Different ROSs induced by CSF were responsible for the oxidation of As(III) under different conditions. • I could promote the oxidation of As(III) by accelerating Fe(III)/Fe(II) cycle. • A surface-mediated reaction mechanism was proposed. Abstract Arsenite oxidation is commonly found during the removal of arsenite by iron minerals. The influencing factors and mechanisms of As(III) oxidation in reactive carbonate structural Fe(II) (CSF) suspensions were investigated in this study. Results showed that oxidation efficiency of As(III) was susceptible to CSF dosage, initial pH and dissolved oxygen (DO). It is interesting to note that the presence of iodide could conspicuously facilitate the oxidation efficiency of As(III) by accelerating Fe(III)/Fe(II) cycle. Scavenging experiments demonstrated that H 2 O 2 and ·O 2 – were the crucial ROSs in the pH range of 5.0–9.0. Besides, the other predominant ROSs accounting for As(III) oxidation were Fe(IV) and surface-bound hydroxyl radical (·OH) in acid and neutral solutions while Fe(IV) became the main oxidant in alkaline solutions. Production of ROSs was attributed to the oxygenation of Fe2+ adsorbed on Fe(III) oxyhydroxides and complexed Fe(II) under neutral condition. No ROSs could be examined in the liquid phase, a surface-mediated mechanism was thus proposed: ROSs were generated on the surface of CSF while As(III) was adsorbed on the surface of CSF and then oxidized to As(V) by surface-bound ROSs. This study may shed light on molecular oxygen activation mechanism by carbonate structural Fe(II) during arsenite oxidation. [ABSTRACT FROM AUTHOR]

View large Download slide View large Download slide OBJECTIVES Our goal was to determine the range of perioperative mortality rates associated with the Ross procedure that results in a life expectancy similar to that seen with mechanical aortic valve replacement (mAVR) in young patients with aortic valve disease. METHODS A fully probabilistic Markov microsimulation model with 1000 outer loops and 10 000 inner loops was constructed to compare gain in life expectancy and quality-adjusted life years between the index treatment with the Ross procedure versus mAVR for a theoretical cohort of young patients with aortic valve disease. Inputs for early deaths and late complications (death, stroke, bleeding, reoperation) were obtained from a single-centre study of 208 propensity score matched patients. In the primary analysis, the perioperative mortality rate for the Ross procedure was varied by increments of 0.5% to determine its impact on life expectancy and quality-adjusted life years. A 2-way sensitivity analysis was conducted to determine simultaneously the impact of the Ross reoperation rate and Ross reoperative mortality rate on life expectancy. RESULTS Life expectancy was improved with the Ross procedure when the perioperative mortality rate with the Ross procedure was <2.5% and was equivalent to mAVR when the mortality rate was 2.5% to 5%. Similarly, when the perioperative mortality rate of the Ross procedure was between 4% and 5.5%, the quality-adjusted life years gained were similar between the Ross procedure and mAVR. Life expectancy was improved when the Ross procedure reoperative mortality rate was <7% at an incidence of Ross reoperations of 18% at 20 years. CONCLUSIONS Improved life expectancy can be expected with the Ross procedure when the operative mortality rate is less than 2.5%. [ABSTRACT FROM AUTHOR]

Background Neo-aortic root dilatation accounts for the majority of reoperations needed after the Ross procedure with implantation of the pulmonary autograft as complete root replacement. This study evaluates early results of external prosthetic reinforcement of the autograft. Methods From July 2015 to October 2017, 16 adolescent and adult patients received a Ross procedure at our department by this technique. A congenital-dysplastic valve was present in 13 patients, including 9 patients with a bicuspid aortic valve. Clinical and echocardiographic follow-up is complete with a mean duration of 19.7 ± 5.8 months. Results The mean age at operation was 27.1 ± 16.1 years. Mean aortic cross-clamping time was 102 ± 39 minutes. No bleeding complication occurred. The median stay on the intensive care unit was 2 days. In-hospital mortality was 0%. All patients were discharged with no or trivial aortic regurgitation. In one patient both the autograft andhomograftwere replaced because of endocarditis 3 months after the primary operation, leading to 93.8% freedom from reoperation at 2 years. There were no late deaths during the study period. The latest echocardiography confirmed absence of aortic regurgitation grade >I in all patients. Neo-aortic root diameters remained stable during follow-up. Conclusion The presented modification of the Ross procedure does not prolong ischemia time, and can be performed with a low operativemorbidity andmortality and an excellent early valve function. [ABSTRACT FROM AUTHOR]

The mixing process greatly influence the mixing efficiency, as well as the quality and the price of the intermediate and/or the final product. Static mixer is used for premixing action before the main mixing process, for significant reduction of mixing time and energy consumption. This type of premixing action is not investigated in detail in the open literature. In this article, the novel numerical approach called Discrete Element Method is used for modelling of granular flow in multiple static mixer applications (1 - 3 Komax or Ross mixing elements were utilized), while the Computational Fluid Dynamic method was chosen for fluid flow modelling, using the Eulerian multiphase model. The main aim of this article is to predict the behaviour of granules being gravitationally transported in different mixer configuration and to choose the best configuration of the mixer taking into account the total particle path, the number of mixing elements and the quality of the obtained mixture. The results of the numerical simulations in the static mixers were compared to experimental results, the mixing quality is examined by RSD (relative standard deviation) criterion, and the effects on the mixer type and the number of mixing elements on mixing process were studied. The effects of the mixer type and the number of mixing elements on mixing process were studied using analysis of variance (ANOVA). Mathematical modelling is used for optimization of number of Ross and Komax segments in mixer in order to gain desirable mixing results. [Projekat Ministarstva nauke Republike Srbije, br. TR31055]

Fayoumi chickens are believed to be more disease resistant compared to commercial broiler chickens. The objective of this study was to compare mRNA expression of intestinal nutrient transporters, digestive enzymes, and host defense peptides (HDP) between Eimeria maxima -challenged Fayoumi and Ross broiler chickens. At 21 d of age, Ross broilers and Fayoumi lines M5.1 and M15.2 were challenged with 1,000 E. maxima oocysts. Control birds were not challenged. Duodenum, jejunum, and ileum were sampled (n = 6) at 7 d post challenge. Gene expression was analyzed using relative quantification PCR. Data were analyzed by ANOVA and significance level was set at P  < 0.05. There was numerical, but not statistically significant, differential weight gain depression for Ross (15%) and Fayoumi lines M5.1 (21%) and M15.2 (22%) and significant line-specific changes in gene expression. For nutrient transporters, there was downregulation of mRNA for the brush border membrane, amino acid transporters b0,+AT/rBAT, BoAT, and EAAT3 in different segments of the small intestine of Ross and both lines of Fayoumi chickens, indicating that E. maxima challenge likely caused a decrease in nutrient uptake. For HDP, there was downregulation of avian beta defensin (AvBD) 1, 6, 10, 12, and 13 mRNA in the jejunum of the 2 Fayoumi lines, but no change in the Ross broilers. In the duodenum, there was upregulation of AvBD10 mRNA in the Ross and both Fayoumi lines and additionally upregulation of AvBD11, 12, and 13 mRNA in only Fayoumi line M15.2. Liver expressed antimicrobial peptide 2 (LEAP2) mRNA was downregulated in the duodenum and jejunum of Ross and Fayoumi line M5.1 but not in Fayoumi line M15.2. The homeostatic, non-challenged levels of AvBD mRNA were greater in Fayoumi line M15.2 than Ross and Fayoumi line M5.1 in the duodenum and ileum. This study demonstrates tissue- and genetic line-specific transcriptional responses to E. maxima, highlights novel potential candidate genes for response to coccidiosis, and confirms a role for several previously reported genes in response to coccidiosis. [ABSTRACT FROM AUTHOR]

The objective of this study was to estimated gene expression in breast muscles of two broiler strains with used to Myoustatin gene in marketing age (5 weeks of age) under heat stress and compared to control group for 1 hour daily for 7 days in Shalakan farm of Faculty of Agriculture, Ain Shams University, broiler chicks (150 chicks in each strains) of 1 day of age were used in this study. So, the measurements were taken (respiratory rate, rectal temperature and estimated gene expression). The results obtained the gene expression of Myostatin gene in muscle breast was observed highest in Ross strain compared with Indian River strain under heat stress, but no different between strains ( Ross and Indian River) in control group. However, respiratory rate of Ross and Indian River under heat at 5 week of age showed that the Indian River strain was high significant at 5 week of age compared to Ross ones. As shown that rectal temperature of Ross and Indian River were a high significant effect of treatment (heat group was higher from control group) and not a significant of strain. The present experiment was conducted to estimated gene expression on meat quality traits of different tropical stress conditions in different broiler strains during 7 days and 5 weeks of age. Introgressions some major genes likes myostatin gene in muscle breast into broiler improve under the heat stress. [ABSTRACT FROM AUTHOR]

Objective Autograft dilatation is the main long-term complication following the Ross procedure using the freestanding root replacement technique. We reviewed our 25-year experience with the Ross procedure with a special emphasis on valve-sparing reoperations. Methods From 1991 to 2016, 153 patients (29.6 ± 16.6 years; 29.4% pediatric) underwent a Ross operation at our institution with implantation of the autograft as freestanding root replacement. The follow-up is 98.7% complete with a mean of 12.2 ± 5.5 years. Results Mortality at 30-days was 2.0%. Echocardiography documented no or trivial aortic regurgitation in 99.3% of the patients at discharge. Survival probability at 20 years was 85.4%. No case of autograft endocarditis occurred. Autograft deterioration rate was 2.01% per patient-year, and freedom from autograft reoperation was 75.3% at 15 years. A reoperation for autograft aneurysm was required in 35 patients (22.9%) at a mean interval of 11.1 ± 4.6 years after the Ross procedure. A valve-sparing root replacement was performed in 77% of patients, including 10 David and 17 Yacoub procedures with no early mortality. Three patients required prosthetic valve replacement within 2 years after a Yacoub operation. At latest follow-up, 92% of all surviving patients still carry the pulmonary autograft valve. Freedom from autograft valve replacement was 92.1% at 15 years. Conclusions Using the David or Yacoub techniques, the autograft valve can be preserved in the majority of patients with root aneurysms after the Ross procedure. Reoperations can be performed with no early mortality, a good functional midterm result, and an acceptable reintervention rate. [ABSTRACT FROM AUTHOR]

Nature, subaltern and supernatural in The Calcutta Chromosome outweighs the scientific claims as Ghosh narrates history from below. The supernatural manipulation, alleged as absurd and intangible, can be philosophised as the highest form of transcendence. The support to paranormal manipulation against scientific procedures is offered by "other's" acuity to the subtleties of nature gained with their communion with nature which is not in line with modern science. To rationalise, if not concretise, such native intelligence celebrates the antiquated human-nature communion with no less regret for the recession in the same. Under the silk thin veil of silence of the "other", the vibrancy and maturity of intellect can be descried. [ABSTRACT FROM AUTHOR]