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1. Medical emergencies at sea: an analysis of ambulance-supported and autonomously performed operations by lifeboat crews

Author: Daphne M. Messelink, Gert-Jan van der Ploeg, Theo van der Linden, Roos D. Flameling, and Joost J. L. M. Bierens
Subjects: Lifeboat crew, Sea rescue, Ambulance crew, Search and rescue, Dispatch, Telemedicine, Special situations and conditions, RC952-1245, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract: Abstract Background Very little data is available about the involvement of lifeboat crews in medical emergencies at sea. The aim of this study is to analyze the medical operations at sea performed by the Royal Netherlands Sea Rescue Institution (KNRM). Methods This is a retrospective descriptive analysis of all medical operations at sea performed by the KNRM between January 2017 and January 2020. The operations were divided in three groups: with ambulance crew aboard the lifeboat, ambulance crew on land waiting for the arrival of the lifeboat, and autonomous operations (without ambulance crew involvement). The main outcome measures were circumstances, encountered medical problems, follow-up and crew departure time. Results The KNRM performed 282 medical operations, involving 361 persons. Operations with ambulance crew aboard the lifeboat (n = 39; 42 persons) consisted mainly of persons with serious trauma or injuries; 32 persons (76.2%) were transported to a hospital. Operations with ambulance crew on land (n = 153; 188 persons) mainly consisted of situations where time was essential, such as persons who were still in the water, with risk of drowning (n = 45, 23.9%), on-going resuscitations (n = 9, 4.8%) or suicide attempts (n = 7, 3.7%). 101 persons (53,7%) were transported to a hospital. All persons involved in the autonomous operations (n = 90; 131 persons) had minor injuries. 38 persons (29%) needed additional medical care, mainly for (suspected) fractures or stitches. In 115 (40.8%) of all operations lifeboat crews did not know that there was a medical problem at the time of departure. Crew departure time in operations with ambulance crew aboard the lifeboat (13.7 min, min. 0, max. 25, SD 5.74 min.) was significantly longer than in operations with ambulance crew on land (7.7 min, min. 0, max 21, SD 4.82 min., p
Published: 2023
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2. Prediction of Isolated Local Recurrence After Resection of Pancreatic Ductal Adenocarcinoma: A Nationwide Study

Author: van Goor, I. W. J. M., Andel, P. C. M., Buijs, F. S., Besselink, M. G., Bonsing, B. A., Bosscha, K., Busch, O. R., Cirkel, G. A., van Dam, R. M., Festen, S., Koerkamp, B. Groot, van der Harst, E., de Hingh, I. H. J. T., Kazemier, G., Liem, M. S. L., Meijer, G., de Meijer, V. E., Nieuwenhuijs, V. B., Roos, D., Schreinemakers, J. M. J., Stommel, M. W. J., Wit, F., Verdonk, R. C., van Santvoort, H. C., Molenaar, I. Q., Intven, M. P. W., and Daamen, L. A.
Published: 2024
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3. What drives wild boar density and population growth in Mediterranean environments?

Author: Colomer, J., Massei, G., Roos, D., Rosell, C., and Rodríguez-Teijeiro, J.D.
Published: 2024
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4. ASO Visual Abstract: Short- and Long-Term Outcomes of Pancreatic Cancer Resection for Elderly Patients: A Nationwide Analysis

Author: Henry, A. C., Schouten, T. J., Daamen, L. A., Walma, M. S., Noordzij, P., Cirkel, G. A., Los, M., Besselink, M. G., Busch, O. R., Bonsing, B. A., Bosscha, K., van Dam, R. M., Festen, S., Groot Koerkamp, B., van der Harst, E., de Hingh, I. H. J. T., Kazemier, G., Liem, M. S., de Meijer, V. E., Nieuwenhuijs, V. B., Roos, D., Schreinemakers, J. M. J., Stommel, M. W. J., Molenaar, I. Q., and van Santvoort, H. C.
Published: 2022
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5. Stoma-free survival after anastomotic leak following rectal cancer resection: worldwide cohort of 2470 patients

Author: Greijdanus, N, Wienholts, K, Ubels, S, Talboom, K, Hannink, G, Wolthuis, A, de Lacy, F, Lefevre, J, Solomon, M, Frasson, M, Rotholtz, N, Denost, Q, Perez, R, Konishi, T, Panis, Y, Rutegard, M, Hompes, R, Rosman, C, van Workum, F, Tanis, P, de Wilt, J, Bremers, A, Ferenschild, F, de Vriendt, S, D'Hoore, A, Bislenghi, G, Farguell, J, Lacy, A, Atienza, P, van Kessel, C, Parc, Y, Voron, T, Collard, M, Muriel, J, Cholewa, H, Mattioni, L, Frontali, A, Polle, S, Polat, F, Obihara, N, Vailati, B, Kusters, M, Tuynmann, J, Hazen, S, Gruter, A, Amano, T, Fujiwara, H, Salomon, M, Ruiz, H, Gonzalez, R, Estefania, D, Avellaneda, N, Carrie, A, Santillan, M, Pachajoa, D, Parodi, M, Gielis, M, Binder, A, Gurtler, T, Riedl, P, Badiani, S, Berney, C, Morgan, M, Hollington, P, da Silva, N, Nair, G, Ho, Y, Lamparelli, M, Kapadia, R, Kroon, H, Dudi-Venkata, N, Liu, J, Sammour, T, Flamey, N, Pattyn, P, Chaoui, A, Vansteenbrugge, L, van den Broek, N, Vanclooster, P, de Gheldere, C, Pletinckx, P, Defoort, B, Dewulf, M, Slavchev, M, Belev, N, Atanasov, B, Krastev, P, Sokolov, M, Maslyankov, S, Gribnev, P, Pavlov, V, Ivanov, T, Karamanliev, M, Filipov, E, Tonchev, P, Aigner, F, Mitteregger, M, Allmer, C, Seitinger, G, Colucci, N, Buchs, N, Ris, F, Toso, C, Gialamas, E, Vuagniaux, A, Chautems, R, Sauvain, M, Daester, S, von Flue, M, Guenin, M, Taha-Mehlitz, S, Hess, G, Martinek, L, Skrovina, M, Machackova, M, Bencurik, V, Uluk, D, Pratschke, J, Dittrich, L, Guel-Klein, S, Perez, D, Grass, J, Melling, N, Mueller, S, Iversen, L, Eriksen, J, Baatrup, G, Al-Najami, I, Bjorsum-Meyer, T, Teras, J, Teras, R, Monib, F, Ahmed, N, Alkady, E, Ali, A, Khedr, G, Abdelaal, A, Ashoush, F, Ewedah, M, Elshennawy, E, Hussein, M, Fernandez-Martinez, D, Garcia-Florez, L, Fernandez-Hevia, M, Suarez-Sanchez, A, Aretxabala, I, Docampo, I, Zabala, J, Tejedor, P, Morales Bernaldo de Quiros, J, Quiroga, I, Navarro-Sanchez, A, Darias, I, Fernandez, C, de La Cruz Cuadrado, C, Sanchez-Guillen, L, Lopez-Rodriguez-Arias, F, Soler-Silva, A, Arroyo, A, Bernal-Sprekelsen, J, Gomez-Abril, S, Gonzalvez, P, Torres, M, Sanchez, T, Antona, F, Lara, J, Montero, J, Mendoza-Moreno, F, Diez-Alonso, M, Matias-Garcia, B, Quiroga-Valcarcel, A, Colas-Ruiz, E, Tasende-Presedo, M, Fernandez-Hurtado, I, Cifuentes-Rodenas, J, Suarez, M, Losada, M, Hernandez, M, Alonso, A, Dieguez, B, Serralta, D, Quintana, R, Lopez, J, Pinto, F, Nieto-Moreno, E, Bonito, A, Santacruz, C, Marcos, E, Septiem, J, Calero-Lillo, A, Alanez-Saavedra, J, Munoz-Collado, S, Lopez-Lara, M, Martinez, M, Herrero, E, Borda, F, Villar, O, Escartin, J, Blas, J, Ferrer, R, Egea, J, Rodriguez-Infante, A, Minguez-Ruiz, G, Carreno-Villarreal, G, Pire-Abaitua, G, Dziakova, J, Rodriguez, C, Aranda, M, Huguet, J, Borda-Arrizabalaga, N, Enriquez-Navascues, J, Echaniz, G, Ansorena, Y, Estaire-Gomez, M, Martinez-Pinedo, C, Barbero-Valenzuela, A, Ruiz-Garcia, P, Kraft, M, Gomez-Jurado, M, Pellino, G, Espin-Basany, E, Cotte, E, Panel, N, Goutard, C, de Angelis, N, Lauka, L, Shaikh, S, Osborne, L, Ramsay, G, Nichita, V, Bhandari, S, Sarmah, P, Bethune, R, Pringle, H, Massey, L, Fowler, G, Hamid, H, de Simone, B, Kynaston, J, Bradley, N, Stienstra, R, Gurjar, S, Mukherjee, T, Chandio, A, Ahmed, S, Singh, B, Runau, F, Chaudhri, S, Siaw, O, Sarveswaran, J, Miu, V, Ashmore, D, Darwich, H, Singh-Ranger, D, Singh, N, Shaban, M, Gareb, F, Petropolou, T, Polydorou, A, Dattani, M, Afzal, A, Bavikatte, A, Sebastian, B, Ward, N, Mishra, A, Manatakis, D, Agalianos, C, Tasis, N, Antonopoulou, M, Karavokyros, I, Charalabopoulos, A, Schizas, D, Baili, E, Syllaios, A, Karydakis, L, Vailas, M, Balalis, D, Korkolis, D, Plastiras, A, Rompou, A, Xenaki, S, Xynos, E, Chrysos, E, Venianaki, M, Christodoulidis, G, Perivoliotis, K, Tzovaras, G, Baloyiannis, I, Ho, M, Ng, S, Mak, T, Futaba, K, Santak, G, Simlesa, D, Cosic, J, Zukanovic, G, Kelly, M, Larkin, J, Mccormick, P, Mehigan, B, Connelly, T, Neary, P, Ryan, J, Mccullough, P, Al-Juaifari, M, Hammoodi, H, Abbood, A, Calabro, M, Muratore, A, La Terra, A, Farnesi, F, Feo, C, Fabbri, N, Pesce, A, Fazzin, M, Roscio, F, Clerici, F, Lucchi, A, Vittori, L, Agostinelli, L, Ripoli, M, Sambucci, D, Porta, A, Sinibaldi, G, Crescentini, G, Larcinese, A, Picone, E, Persiani, R, Biondi, A, Pezzuto, R, Lorenzon, L, Rizzo, G, Coco, C, D'Agostino, L, Spinelli, A, Sacchi, M, Carvello, M, Foppa, C, Maroli, A, Palini, G, Garulli, G, Zanini, N, Delrio, P, Rega, D, Carbone, F, Aversano, A, Pirozzolo, G, Recordare, A, D'Alimonte, L, Vignotto, C, Corbellini, C, Sampietro, G, Lorusso, L, Manzo, C, Ghignone, F, Ugolini, G, Montroni, I, Pasini, F, Ballabio, M, Bisagni, P, Armao, F, Longhi, M, Ghazouani, O, Galleano, R, Tamini, N, Oldani, M, Nespoli, L, Picciariello, A, Altomare, D, Tomasicchio, G, Lantone, G, Catena, F, Giuffrida, M, Annicchiarico, A, Perrone, G, Grossi, U, Santoro, G, Zanus, G, Iacomino, A, Novello, S, Passuello, N, Zucchella, M, Puca, L, Degiuli, M, Reddavid, R, Scabini, S, Aprile, A, Soriero, D, Fioravanti, E, Rottoli, M, Romano, A, Tanzanu, M, Belvedere, A, Mariani, N, Ceretti, A, Opocher, E, Gallo, G, Sammarco, G, de Paola, G, Pucciarelli, S, Marchegiani, F, Spolverato, G, Buzzi, G, Di Saverio, S, Meroni, P, Parise, C, Bottazzoli, E, Lapolla, P, Brachini, G, Cirillo, B, Mingoli, A, Sica, G, Siragusa, L, Bellato, V, Cerbo, D, de Pasqual, C, de Manzoni, G, di Cosmo, M, Alrayes, B, Qandeel, M, Hani, M, Rabadi, A, el Muhtaseb, M, Abdeen, B, Karmi, F, Zilinskas, J, Latkauskas, T, Tamelis, A, Pikuniene, I, Slenfuktas, V, Poskus, T, Kryzauskas, M, Jakubauskas, M, Mikalauskas, S, Jakubauskiene, L, Hassan, S, Altrabulsi, A, Abdulwahed, E, Ghmagh, R, Deeknah, A, Alshareea, E, Elhadi, M, Abujamra, S, Msherghi, A, Tababa, O, Majbar, M, Souadka, A, Benkabbou, A, Mohsine, R, Echiguer, S, Moctezuma-Velazquez, P, Salgado-Nesme, N, Vergara-Fernandez, O, Sainz-Hernandez, J, Alvarez-Bautista, F, Zakaria, A, Zakaria, Z, Wong, M, Ismail, R, Ibrahim, A, Abdullah, N, Julaihi, R, Bhat, S, O'Grady, G, Bissett, I, Lamme, B, Musters, G, Dinaux, A, Grotenhuis, B, Steller, E, Aalbers, A, Leeuwenburgh, M, Rutten, H, Burger, J, Bloemen, J, Ketelaers, S, Waqar, U, Chawla, T, Rauf, H, Rani, P, Talsma, A, Scheurink, L, van Praagh, J, Segelman, J, Nygren, J, Anderin, K, Tiefenthal, M, de Andres, B, Beltran de Heredia, J, Vazquez, A, Gomez, T, Golshani, P, Kader, R, Mohamed, A, Westerterp, M, Marinelli, A, Niemer, Q, Doornebosch, P, Shapiro, J, Vermaas, M, de Graaf, E, van Westreenen, H, Zwakman, M, van Dalsen, A, Vles, W, Nonner, J, Toorenvliet, B, Janssen, P, Verdaasdonk, E, Amelung, F, Peeters, K, Bahadoer, R, Holman, F, Heemskerk, J, Vosbeek, N, Leijtens, J, Taverne, S, Heijnen, B, El-Massoudi, Y, de Groot-Van Veen, I, Hoff, C, Jou-Valencia, D, Consten, E, Burghgraef, T, Geitenbeek, R, Hulshof, L, Slooter, G, Reudink, M, Bouvy, N, Wildeboer, A, Verstappen, S, Pennings, A, van den Hengel, B, Wijma, A, de Haan, J, de Nes, L, Heesink, V, Karsten, T, Heidsma, C, Koemans, W, Dekker, J, van der Zijden, C, Roos, D, Demirkiran, A, van der Burg, S, Oosterling, S, Hoogteijling, T, Wiering, B, Smeeing, D, Havenga, K, Lutfi, H, Tsimogiannis, K, Skoldberg, F, Folkesson, J, den Boer, F, van Schaik, T, van Gerven, P, Sietses, C, Hol, J, Boerma, E, Creemers, D, Schultz, J, Frivold, T, Riis, R, Gregussen, H, Busund, S, Sjo, O, Gaard, M, Krohn, N, Ersryd, A, Leung, E, Sultan, H, Hajjaj, B, Alhisi, A, Khader, A, Mendes, A, Semiao, M, Faria, L, Azevedo, C, da Costa Devesa, H, Martins, S, Jarimba, A, Marques, S, Ferreira, R, Oliveira, A, Ferreira, C, Pereira, R, Surlin, V, Graure, G, Ramboiu, S, Negoi, I, Ciubotaru, C, Stoica, B, Tanase, I, Negoita, V, Florea, S, Macau, F, Vasile, M, Stefanescu, V, Dimofte, G, Lunca, S, Roata, C, Musina, A, Garmanova, T, Agapov, M, Markaryan, D, Eduard, G, Yanishev, A, Abelevich, A, Bazaev, A, Rodimov, S, Filimonov, V, Melnikov, A, Suchkov, I, Drozdov, E, Kostromitskiy, D, Sjostrom, O, Matthiessen, P, Baban, B, Gadan, S, Jadid, K, Staffan, M, Park, J, Rydbeck, D, Lydrup, M, Buchwald, P, Jutesten, H, Darlin, L, Lindqvist, E, Nilsson, K, Larsson, P, Jangmalm, S, Kosir, J, Tomazic, A, Grosek, J, Bozic, T, Zazo, A, Zazo, R, Fares, H, Ayoub, K, Niazi, A, Mansour, A, Abbas, A, Tantoura, M, Hamdan, A, Hassan, N, Hasan, B, Saad, A, Sebai, A, Haddad, A, Maghrebi, H, Kacem, M, Yalkin, O, Samsa, M, Atak, I, Balci, B, Haberal, E, Dogan, L, Gecim, I, Akyol, C, Koc, M, Sivrikoz, E, Piyadeoglu, D, Avanagh, D, Sokmen, S, Bisgin, T, Gunenc, E, Guzel, M, Leventoglu, S, Yuksel, O, Kozan, R, Gobut, H, Cengiz, F, Erdinc, K, Acar, N, Kamer, E, Ozgur, I, Aydin, O, Keskin, M, Bulut, M, Kulle, C, Kara, Y, Sibic, O, Ozata, I, Bugra, D, Balik, E, Cakir, M, Alhardan, A, Colak, E, Aybar, A, Sari, A, Atici, S, Kaya, T, Dursun, A, Calik, B, Ozkan, O, Ulgur, H, Duzgun, O, Monson, J, George, S, Woods, K, Al-Eryani, F, Albakry, R, Coetzee, E, Boutall, A, Herman, A, Warden, C, Mugla, N, Forgan, T, Mia, I, Lambrechts, A, Greijdanus N. G., Wienholts K., Ubels S., Talboom K., Hannink G., Wolthuis A., de Lacy F. B., Lefevre J. H., Solomon M., Frasson M., Rotholtz N., Denost Q., Perez R. O., Konishi T., Panis Y., Rutegard M., Hompes R., Rosman C., van Workum F., Tanis P. J., de Wilt J. H. W., Bremers A. J. A., Ferenschild F. T., de Vriendt S., D'Hoore A., Bislenghi G., Farguell J., Lacy A. M., Atienza P. G., van Kessel C. S., Parc Y., Voron T., Collard M. K., Muriel J. S., Cholewa H., Mattioni L. A., Frontali A., Polle S. W., Polat F., Obihara N. J., Vailati B. B., Kusters M., Tuynmann J. B., Hazen S. J. A., Gruter A. A. J., Amano T., Fujiwara H., Salomon M., Ruiz H., Gonzalez R., Estefania D., Avellaneda N., Carrie A., Santillan M., Pachajoa D. A. P., Parodi M., Gielis M., Binder A. -D., Gurtler T., Riedl P., Badiani S., Berney C., Morgan M., Hollington P., da Silva N., Nair G., Ho Y. M., Lamparelli M., Kapadia R., Kroon H. M., Dudi-Venkata N. N., Liu J., Sammour T., Flamey N., Pattyn P., Chaoui A., Vansteenbrugge L., van den Broek N. E. J., Vanclooster P., de Gheldere C., Pletinckx P., Defoort B., Dewulf M., Slavchev M., Belev N., Atanasov B., Krastev P., Sokolov M., Maslyankov S., Gribnev P., Pavlov V., Ivanov T., Karamanliev M., Filipov E., Tonchev P., Aigner F., Mitteregger M., Allmer C., Seitinger G., Colucci N., Buchs N., Ris F., Toso C., Gialamas E., Vuagniaux A., Chautems R., Sauvain M. -O., Daester S., von Flue M., Guenin M. -O., Taha-Mehlitz S., Hess G. F., Martinek L., Skrovina M., Machackova M., Bencurik V., Uluk D., Pratschke J., Dittrich L. S., Guel-Klein S., Perez D., Grass J. -K., Melling N., Mueller S., Iversen L. H., Eriksen J. D., Baatrup G., Al-Najami I., Bjorsum-Meyer T., Teras J., Teras R. M., Monib F. A., Ahmed N. E. A. E., Alkady E., Ali A. K., Khedr G. A. E., Abdelaal A. S., Ashoush F. M. B., Ewedah M., Elshennawy E. M., Hussein M., Fernandez-Martinez D., Garcia-Florez L. J., Fernandez-Hevia M., Suarez-Sanchez A., Aretxabala I. D. H., Docampo I. L., Zabala J. G., Tejedor P., Morales Bernaldo de Quiros J. T., Quiroga I. B., Navarro-Sanchez A., Darias I. S., Fernandez C. L., de La Cruz Cuadrado C., Sanchez-Guillen L., Lopez-Rodriguez-Arias F., Soler-Silva A., Arroyo A., Bernal-Sprekelsen J. C., Gomez-Abril S. A., Gonzalvez P., Torres M. T., Sanchez T. R., Antona F. B., Lara J. E. S., Montero J. A. A., Mendoza-Moreno F., Diez-Alonso M., Matias-Garcia B., Quiroga-Valcarcel A., Colas-Ruiz E., Tasende-Presedo M. M., Fernandez-Hurtado I., Cifuentes-Rodenas J. A., Suarez M. C., Losada M., Hernandez M., Alonso A., Dieguez B., Serralta D., Quintana R. E. M., Lopez J. M. G., Pinto F. L., Nieto-Moreno E., Bonito A. C., Santacruz C. C., Marcos E. B., Septiem J. G., Calero-Lillo A., Alanez-Saavedra J., Munoz-Collado S., Lopez-Lara M., Martinez M. L., Herrero E. F., Borda F. J. G., Villar O. G., Escartin J., Blas J. L., Ferrer R., Egea J. G., Rodriguez-Infante A., Minguez-Ruiz G., Carreno-Villarreal G., Pire-Abaitua G., Dziakova J., Rodriguez C. S. -C., Aranda M. J. P., Huguet J. M. M., Borda-Arrizabalaga N., Enriquez-Navascues J. M., Echaniz G. E., Ansorena Y. S., Estaire-Gomez M., Martinez-Pinedo C., Barbero-Valenzuela A., Ruiz-Garcia P., Kraft M., Gomez-Jurado M. J., Pellino G., Espin-Basany E., Cotte E., Panel N., Goutard C. -A., de Angelis N., Lauka L., Shaikh S., Osborne L., Ramsay G., Nichita V. -I., Bhandari S., Sarmah P., Bethune R. M., Pringle H. C. M., Massey L., Fowler G. E., Hamid H. K. S., de Simone B. D., Kynaston J., Bradley N., Stienstra R. M., Gurjar S., Mukherjee T., Chandio A., Ahmed S., Singh B., Runau F., Chaudhri S., Siaw O., Sarveswaran J., Miu V., Ashmore D., Darwich H., Singh-Ranger D., Singh N., Shaban M., Gareb F., Petropolou T., Polydorou A., Dattani M., Afzal A., Bavikatte A., Sebastian B., Ward N., Mishra A., Manatakis D., Agalianos C., Tasis N., Antonopoulou M. -I., Karavokyros I., Charalabopoulos A., Schizas D., Baili E., Syllaios A., Karydakis L., Vailas M., Balalis D., Korkolis D., Plastiras A., Rompou A., Xenaki S., Xynos E., Chrysos E., Venianaki M., Christodoulidis G., Perivoliotis K., Tzovaras G., Baloyiannis I., Ho M. -F., Ng S. S., Mak T. W. -C., Futaba K., Santak G., Simlesa D., Cosic J., Zukanovic G., Kelly M. E., Larkin J. O., McCormick P. H., Mehigan B. J., Connelly T. M., Neary P., Ryan J., McCullough P., Al-Juaifari M. A., Hammoodi H., Abbood A. H., Calabro M., Muratore A., La Terra A., Farnesi F., Feo C. V., Fabbri N., Pesce A., Fazzin M., Roscio F., Clerici F., Lucchi A., Vittori L., Agostinelli L., Ripoli M. C., Sambucci D., Porta A., Sinibaldi G., Crescentini G., Larcinese A., Picone E., Persiani R., Biondi A., Pezzuto R., Lorenzon L., Rizzo G., Coco C., D'Agostino L., Spinelli A., Sacchi M. M., Carvello M., Foppa C., Maroli A., Palini G. M., Garulli G., Zanini N., Delrio P., Rega D., Carbone F., Aversano A., Pirozzolo G., Recordare A., D'Alimonte L., Vignotto C., Corbellini C., Sampietro G. M., Lorusso L., Manzo C. A., Ghignone F., Ugolini G., Montroni I., Pasini F., Ballabio M., Bisagni P., Armao F. T., Longhi M., Ghazouani O., Galleano R., Tamini N., Oldani M., Nespoli L., Picciariello A., Altomare D. F., Tomasicchio G., Lantone G., Catena F., Giuffrida M., Annicchiarico A., Perrone G., Grossi U., Santoro G. A., Zanus G., Iacomino A., Novello S., Passuello N., Zucchella M., Puca L., deGiuli M., Reddavid R., Scabini S., Aprile A., Soriero D., Fioravanti E., Rottoli M., Romano A., Tanzanu M., Belvedere A., Mariani N. M., Ceretti A. P., Opocher E., Gallo G., Sammarco G., de Paola G., Pucciarelli S., Marchegiani F., Spolverato G., Buzzi G., Di Saverio S., Meroni P., Parise C., Bottazzoli E. I., Lapolla P., Brachini G., Cirillo B., Mingoli A., Sica G., Siragusa L., Bellato V., Cerbo D., de Pasqual C. A., de Manzoni G., di Cosmo M. A., Alrayes B. M. H., Qandeel M. W. M., Hani M. B., Rabadi A., el Muhtaseb M. S., Abdeen B., Karmi F., Zilinskas J., Latkauskas T., Tamelis A., Pikuniene I., Slenfuktas V., Poskus T., Kryzauskas M., Jakubauskas M., Mikalauskas S., Jakubauskiene L., Hassan S. Y., Altrabulsi A., Abdulwahed E., Ghmagh R., Deeknah A., Alshareea E., Elhadi M., Abujamra S., Msherghi A. A., Tababa O. W. E., Majbar M. A., Souadka A., Benkabbou A., Mohsine R., Echiguer S., Moctezuma-Velazquez P., Salgado-Nesme N., Vergara-Fernandez O., Sainz-Hernandez J. C., Alvarez-Bautista F. E., Zakaria A. D., Zakaria Z., Wong M. P. K., Ismail R., Ibrahim A. F., Abdullah N. A. N., Julaihi R., Bhat S., O'Grady G., Bissett I., Lamme B., Musters G. D., Dinaux A. M., Grotenhuis B. A., Steller E. J., Aalbers A. G. J., Leeuwenburgh M. M., Rutten H. J. T., Burger J. W. A., Bloemen J. G., Ketelaers S. H. J., Waqar U., Chawla T., Rauf H., Rani P., Talsma A. K., Scheurink L., van Praagh J. B., Segelman J., Nygren J., Anderin K., Tiefenthal M., de Andres B., Beltran de Heredia J. P., Vazquez A., Gomez T., Golshani P., Kader R., Mohamed A., Westerterp M., Marinelli A., Niemer Q., Doornebosch P. G., Shapiro J., Vermaas M., de Graaf E. J. R., van Westreenen H. L., Zwakman M., van Dalsen A. D., Vles W. J., Nonner J., Toorenvliet B. R., Janssen P. T. J., Verdaasdonk E. G. G., Amelung F. J., Peeters K. C. M. J., Bahadoer R. R., Holman F. A., Heemskerk J., Vosbeek N., Leijtens J. W. A., Taverne S. B. M., Heijnen B. H. M., El-Massoudi Y., de Groot-Van Veen I., Hoff C., Jou-Valencia D., Consten E. C. J., Burghgraef T. A., Geitenbeek R., Hulshof L. G. W. L., Slooter G. D., Reudink M., Bouvy N. D., Wildeboer A. C. L., Verstappen S., Pennings A. J., van den Hengel B., Wijma A. G., de Haan J., de Nes L. C. F., Heesink V., Karsten T., Heidsma C. M., Koemans W. J., Dekker J. -W. T., van der Zijden C. J., Roos D., Demirkiran A., van der Burg S., Oosterling S. J., Hoogteijling T. J., Wiering B., Smeeing D. P. J., Havenga K., Lutfi H., Tsimogiannis K., Skoldberg F., Folkesson J., den Boer F., van Schaik T. G., van Gerven P., Sietses C., Hol J. C., Boerma E. -J. G., Creemers D. M. J., Schultz J. K., Frivold T., Riis R., Gregussen H., Busund S., Sjo O. H., Gaard M., Krohn N., Ersryd A. L., Leung E., Sultan H., Hajjaj B. N., Alhisi A. J., Khader A. A. E., Mendes A. F. D., Semiao M., Faria L. Q., Azevedo C., da Costa Devesa H. M., Martins S. F., Jarimba A. M. R., Marques S. M. R., Ferreira R. M., Oliveira A., Ferreira C., Pereira R., Surlin V. M., Graure G. M., Ramboiu S. P. S. D., Negoi I., Ciubotaru C., Stoica B., Tanase I., Negoita V. M., Florea S., Macau F., Vasile M., Stefanescu V., Dimofte G. -M., Lunca S., Roata C. -E., Musina A. -M., Garmanova T., Agapov M. N., Markaryan D. G., Eduard G., Yanishev A., Abelevich A., Bazaev A., Rodimov S. V., Filimonov V. B., Melnikov A. A., Suchkov I. A., Drozdov E. S., Kostromitskiy D. N., Sjostrom O., Matthiessen P., Baban B., Gadan S., Jadid K. D., Staffan M., Park J. M., Rydbeck D., Lydrup M. -L., Buchwald P., Jutesten H., Darlin L., Lindqvist E., Nilsson K., Larsson P. -A., Jangmalm S., Kosir J. A., Tomazic A., Grosek J., Bozic T. K., Zazo A., Zazo R., Fares H., Ayoub K., Niazi A., Mansour A., Abbas A., Tantoura M., Hamdan A., Hassan N., Hasan B., Saad A., Sebai A., Haddad A., Maghrebi H., Kacem M., Yalkin O., Samsa M. V., Atak I., Balci B., Haberal E., Dogan L., Gecim I. E., Akyol C., Koc M. A., Sivrikoz E., Piyadeoglu D., Avanagh D. O., Sokmen S., Bisgin T., Gunenc E., Guzel M., Leventoglu S., Yuksel O., Kozan R., Gobut H., Cengiz F., Erdinc K., Acar N. C., Kamer E., Ozgur I., Aydin O., Keskin M., Bulut M. T., Kulle C. B., Kara Y., Sibic O., Ozata I. H., Bugra D., Balik E., Cakir M., Alhardan A., Colak E., Aybar A. B. C., Sari A. C., Atici S. D., Kaya T., Dursun A., Calik B., Ozkan O. F., Ulgur H. S., Duzgun O., Monson J., George S., Woods K., Al-Eryani F., Albakry R., Coetzee E., Boutall A., Herman A., Warden C., Mugla N., Forgan T., Mia I., Lambrechts A., Greijdanus, N, Wienholts, K, Ubels, S, Talboom, K, Hannink, G, Wolthuis, A, de Lacy, F, Lefevre, J, Solomon, M, Frasson, M, Rotholtz, N, Denost, Q, Perez, R, Konishi, T, Panis, Y, Rutegard, M, Hompes, R, Rosman, C, van Workum, F, Tanis, P, de Wilt, J, Bremers, A, Ferenschild, F, de Vriendt, S, D'Hoore, A, Bislenghi, G, Farguell, J, Lacy, A, Atienza, P, van Kessel, C, Parc, Y, Voron, T, Collard, M, Muriel, J, Cholewa, H, Mattioni, L, Frontali, A, Polle, S, Polat, F, Obihara, N, Vailati, B, Kusters, M, Tuynmann, J, Hazen, S, Gruter, A, Amano, T, Fujiwara, H, Salomon, M, Ruiz, H, Gonzalez, R, Estefania, D, Avellaneda, N, Carrie, A, Santillan, M, Pachajoa, D, Parodi, M, Gielis, M, Binder, A, Gurtler, T, Riedl, P, Badiani, S, Berney, C, Morgan, M, Hollington, P, da Silva, N, Nair, G, Ho, Y, Lamparelli, M, Kapadia, R, Kroon, H, Dudi-Venkata, N, Liu, J, Sammour, T, Flamey, N, Pattyn, P, Chaoui, A, Vansteenbrugge, L, van den Broek, N, Vanclooster, P, de Gheldere, C, Pletinckx, P, Defoort, B, Dewulf, M, Slavchev, M, Belev, N, Atanasov, B, Krastev, P, Sokolov, M, Maslyankov, S, Gribnev, P, Pavlov, V, Ivanov, T, Karamanliev, M, Filipov, E, Tonchev, P, Aigner, F, Mitteregger, M, Allmer, C, Seitinger, G, Colucci, N, Buchs, N, Ris, F, Toso, C, Gialamas, E, Vuagniaux, A, Chautems, R, Sauvain, M, Daester, S, von Flue, M, Guenin, M, Taha-Mehlitz, S, Hess, G, Martinek, L, Skrovina, M, Machackova, M, Bencurik, V, Uluk, D, Pratschke, J, Dittrich, L, Guel-Klein, S, Perez, D, Grass, J, Melling, N, Mueller, S, Iversen, L, Eriksen, J, Baatrup, G, Al-Najami, I, Bjorsum-Meyer, T, Teras, J, Teras, R, Monib, F, Ahmed, N, Alkady, E, Ali, A, Khedr, G, Abdelaal, A, Ashoush, F, Ewedah, M, Elshennawy, E, Hussein, M, Fernandez-Martinez, D, Garcia-Florez, L, Fernandez-Hevia, M, Suarez-Sanchez, A, Aretxabala, I, Docampo, I, Zabala, J, Tejedor, P, Morales Bernaldo de Quiros, J, Quiroga, I, Navarro-Sanchez, A, Darias, I, Fernandez, C, de La Cruz Cuadrado, C, Sanchez-Guillen, L, Lopez-Rodriguez-Arias, F, Soler-Silva, A, Arroyo, A, Bernal-Sprekelsen, J, Gomez-Abril, S, Gonzalvez, P, Torres, M, Sanchez, T, Antona, F, Lara, J, Montero, J, Mendoza-Moreno, F, Diez-Alonso, M, Matias-Garcia, B, Quiroga-Valcarcel, A, Colas-Ruiz, E, Tasende-Presedo, M, Fernandez-Hurtado, I, Cifuentes-Rodenas, J, Suarez, M, Losada, M, Hernandez, M, Alonso, A, Dieguez, B, Serralta, D, Quintana, R, Lopez, J, Pinto, F, Nieto-Moreno, E, Bonito, A, Santacruz, C, Marcos, E, Septiem, J, Calero-Lillo, A, Alanez-Saavedra, J, Munoz-Collado, S, Lopez-Lara, M, Martinez, M, Herrero, E, Borda, F, Villar, O, Escartin, J, Blas, J, Ferrer, R, Egea, J, Rodriguez-Infante, A, Minguez-Ruiz, G, Carreno-Villarreal, G, Pire-Abaitua, G, Dziakova, J, Rodriguez, C, Aranda, M, Huguet, J, Borda-Arrizabalaga, N, Enriquez-Navascues, J, Echaniz, G, Ansorena, Y, Estaire-Gomez, M, Martinez-Pinedo, C, Barbero-Valenzuela, A, Ruiz-Garcia, P, Kraft, M, Gomez-Jurado, M, Pellino, G, Espin-Basany, E, Cotte, E, Panel, N, Goutard, C, de Angelis, N, Lauka, L, Shaikh, S, Osborne, L, Ramsay, G, Nichita, V, Bhandari, S, Sarmah, P, Bethune, R, Pringle, H, Massey, L, Fowler, G, Hamid, H, de Simone, B, Kynaston, J, Bradley, N, Stienstra, R, Gurjar, S, Mukherjee, T, Chandio, A, Ahmed, S, Singh, B, Runau, F, Chaudhri, S, Siaw, O, Sarveswaran, J, Miu, V, Ashmore, D, Darwich, H, Singh-Ranger, D, Singh, N, Shaban, M, Gareb, F, Petropolou, T, Polydorou, A, Dattani, M, Afzal, A, Bavikatte, A, Sebastian, B, Ward, N, Mishra, A, Manatakis, D, Agalianos, C, Tasis, N, Antonopoulou, M, Karavokyros, I, Charalabopoulos, A, Schizas, D, Baili, E, Syllaios, A, Karydakis, L, Vailas, M, Balalis, D, Korkolis, D, Plastiras, A, Rompou, A, Xenaki, S, Xynos, E, Chrysos, E, Venianaki, M, Christodoulidis, G, Perivoliotis, K, Tzovaras, G, Baloyiannis, I, Ho, M, Ng, S, Mak, T, Futaba, K, Santak, G, Simlesa, D, Cosic, J, Zukanovic, G, Kelly, M, Larkin, J, Mccormick, P, Mehigan, B, Connelly, T, Neary, P, Ryan, J, Mccullough, P, Al-Juaifari, M, Hammoodi, H, Abbood, A, Calabro, M, Muratore, A, La Terra, A, Farnesi, F, Feo, C, Fabbri, N, Pesce, A, Fazzin, M, Roscio, F, Clerici, F, Lucchi, A, Vittori, L, Agostinelli, L, Ripoli, M, Sambucci, D, Porta, A, Sinibaldi, G, Crescentini, G, Larcinese, A, Picone, E, Persiani, R, Biondi, A, Pezzuto, R, Lorenzon, L, Rizzo, G, Coco, C, D'Agostino, L, Spinelli, A, Sacchi, M, Carvello, M, Foppa, C, Maroli, A, Palini, G, Garulli, G, Zanini, N, Delrio, P, Rega, D, Carbone, F, Aversano, A, Pirozzolo, G, Recordare, A, D'Alimonte, L, Vignotto, C, Corbellini, C, Sampietro, G, Lorusso, L, Manzo, C, Ghignone, F, Ugolini, G, Montroni, I, Pasini, F, Ballabio, M, Bisagni, P, Armao, F, Longhi, M, Ghazouani, O, Galleano, R, Tamini, N, Oldani, M, Nespoli, L, Picciariello, A, Altomare, D, Tomasicchio, G, Lantone, G, Catena, F, Giuffrida, M, Annicchiarico, A, Perrone, G, Grossi, U, Santoro, G, Zanus, G, Iacomino, A, Novello, S, Passuello, N, Zucchella, M, Puca, L, Degiuli, M, Reddavid, R, Scabini, S, Aprile, A, Soriero, D, Fioravanti, E, Rottoli, M, Romano, A, Tanzanu, M, Belvedere, A, Mariani, N, Ceretti, A, Opocher, E, Gallo, G, Sammarco, G, de Paola, G, Pucciarelli, S, Marchegiani, F, Spolverato, G, Buzzi, G, Di Saverio, S, Meroni, P, Parise, C, Bottazzoli, E, Lapolla, P, Brachini, G, Cirillo, B, Mingoli, A, Sica, G, Siragusa, L, Bellato, V, Cerbo, D, de Pasqual, C, de Manzoni, G, di Cosmo, M, Alrayes, B, Qandeel, M, Hani, M, Rabadi, A, el Muhtaseb, M, Abdeen, B, Karmi, F, Zilinskas, J, Latkauskas, T, Tamelis, A, Pikuniene, I, Slenfuktas, V, Poskus, T, Kryzauskas, M, Jakubauskas, M, Mikalauskas, S, Jakubauskiene, L, Hassan, S, Altrabulsi, A, Abdulwahed, E, Ghmagh, R, Deeknah, A, Alshareea, E, Elhadi, M, Abujamra, S, Msherghi, A, Tababa, O, Majbar, M, Souadka, A, Benkabbou, A, Mohsine, R, Echiguer, S, Moctezuma-Velazquez, P, Salgado-Nesme, N, Vergara-Fernandez, O, Sainz-Hernandez, J, Alvarez-Bautista, F, Zakaria, A, Zakaria, Z, Wong, M, Ismail, R, Ibrahim, A, Abdullah, N, Julaihi, R, Bhat, S, O'Grady, G, Bissett, I, Lamme, B, Musters, G, Dinaux, A, Grotenhuis, B, Steller, E, Aalbers, A, Leeuwenburgh, M, Rutten, H, Burger, J, Bloemen, J, Ketelaers, S, Waqar, U, Chawla, T, Rauf, H, Rani, P, Talsma, A, Scheurink, L, van Praagh, J, Segelman, J, Nygren, J, Anderin, K, Tiefenthal, M, de Andres, B, Beltran de Heredia, J, Vazquez, A, Gomez, T, Golshani, P, Kader, R, Mohamed, A, Westerterp, M, Marinelli, A, Niemer, Q, Doornebosch, P, Shapiro, J, Vermaas, M, de Graaf, E, van Westreenen, H, Zwakman, M, van Dalsen, A, Vles, W, Nonner, J, Toorenvliet, B, Janssen, P, Verdaasdonk, E, Amelung, F, Peeters, K, Bahadoer, R, Holman, F, Heemskerk, J, Vosbeek, N, Leijtens, J, Taverne, S, Heijnen, B, El-Massoudi, Y, de Groot-Van Veen, I, Hoff, C, Jou-Valencia, D, Consten, E, Burghgraef, T, Geitenbeek, R, Hulshof, L, Slooter, G, Reudink, M, Bouvy, N, Wildeboer, A, Verstappen, S, Pennings, A, van den Hengel, B, Wijma, A, de Haan, J, de Nes, L, Heesink, V, Karsten, T, Heidsma, C, Koemans, W, Dekker, J, van der Zijden, C, Roos, D, Demirkiran, A, van der Burg, S, Oosterling, S, Hoogteijling, T, Wiering, B, Smeeing, D, Havenga, K, Lutfi, H, Tsimogiannis, K, Skoldberg, F, Folkesson, J, den Boer, F, van Schaik, T, van Gerven, P, Sietses, C, Hol, J, Boerma, E, Creemers, D, Schultz, J, Frivold, T, Riis, R, Gregussen, H, Busund, S, Sjo, O, Gaard, M, Krohn, N, Ersryd, A, Leung, E, Sultan, H, Hajjaj, B, Alhisi, A, Khader, A, Mendes, A, Semiao, M, Faria, L, Azevedo, C, da Costa Devesa, H, Martins, S, Jarimba, A, Marques, S, Ferreira, R, Oliveira, A, Ferreira, C, Pereira, R, Surlin, V, Graure, G, Ramboiu, S, Negoi, I, Ciubotaru, C, Stoica, B, Tanase, I, Negoita, V, Florea, S, Macau, F, Vasile, M, Stefanescu, V, Dimofte, G, Lunca, S, Roata, C, Musina, A, Garmanova, T, Agapov, M, Markaryan, D, Eduard, G, Yanishev, A, Abelevich, A, Bazaev, A, Rodimov, S, Filimonov, V, Melnikov, A, Suchkov, I, Drozdov, E, Kostromitskiy, D, Sjostrom, O, Matthiessen, P, Baban, B, Gadan, S, Jadid, K, Staffan, M, Park, J, Rydbeck, D, Lydrup, M, Buchwald, P, Jutesten, H, Darlin, L, Lindqvist, E, Nilsson, K, Larsson, P, Jangmalm, S, Kosir, J, Tomazic, A, Grosek, J, Bozic, T, Zazo, A, Zazo, R, Fares, H, Ayoub, K, Niazi, A, Mansour, A, Abbas, A, Tantoura, M, Hamdan, A, Hassan, N, Hasan, B, Saad, A, Sebai, A, Haddad, A, Maghrebi, H, Kacem, M, Yalkin, O, Samsa, M, Atak, I, Balci, B, Haberal, E, Dogan, L, Gecim, I, Akyol, C, Koc, M, Sivrikoz, E, Piyadeoglu, D, Avanagh, D, Sokmen, S, Bisgin, T, Gunenc, E, Guzel, M, Leventoglu, S, Yuksel, O, Kozan, R, Gobut, H, Cengiz, F, Erdinc, K, Acar, N, Kamer, E, Ozgur, I, Aydin, O, Keskin, M, Bulut, M, Kulle, C, Kara, Y, Sibic, O, Ozata, I, Bugra, D, Balik, E, Cakir, M, Alhardan, A, Colak, E, Aybar, A, Sari, A, Atici, S, Kaya, T, Dursun, A, Calik, B, Ozkan, O, Ulgur, H, Duzgun, O, Monson, J, George, S, Woods, K, Al-Eryani, F, Albakry, R, Coetzee, E, Boutall, A, Herman, A, Warden, C, Mugla, N, Forgan, T, Mia, I, Lambrechts, A, Greijdanus N. G., Wienholts K., Ubels S., Talboom K., Hannink G., Wolthuis A., de Lacy F. B., Lefevre J. H., Solomon M., Frasson M., Rotholtz N., Denost Q., Perez R. O., Konishi T., Panis Y., Rutegard M., Hompes R., Rosman C., van Workum F., Tanis P. J., de Wilt J. H. W., Bremers A. J. A., Ferenschild F. T., de Vriendt S., D'Hoore A., Bislenghi G., Farguell J., Lacy A. M., Atienza P. G., van Kessel C. S., Parc Y., Voron T., Collard M. K., Muriel J. S., Cholewa H., Mattioni L. A., Frontali A., Polle S. W., Polat F., Obihara N. J., Vailati B. B., Kusters M., Tuynmann J. B., Hazen S. J. A., Gruter A. A. J., Amano T., Fujiwara H., Salomon M., Ruiz H., Gonzalez R., Estefania D., Avellaneda N., Carrie A., Santillan M., Pachajoa D. A. P., Parodi M., Gielis M., Binder A. -D., Gurtler T., Riedl P., Badiani S., Berney C., Morgan M., Hollington P., da Silva N., Nair G., Ho Y. M., Lamparelli M., Kapadia R., Kroon H. M., Dudi-Venkata N. N., Liu J., Sammour T., Flamey N., Pattyn P., Chaoui A., Vansteenbrugge L., van den Broek N. E. J., Vanclooster P., de Gheldere C., Pletinckx P., Defoort B., Dewulf M., Slavchev M., Belev N., Atanasov B., Krastev P., Sokolov M., Maslyankov S., Gribnev P., Pavlov V., Ivanov T., Karamanliev M., Filipov E., Tonchev P., Aigner F., Mitteregger M., Allmer C., Seitinger G., Colucci N., Buchs N., Ris F., Toso C., Gialamas E., Vuagniaux A., Chautems R., Sauvain M. -O., Daester S., von Flue M., Guenin M. -O., Taha-Mehlitz S., Hess G. F., Martinek L., Skrovina M., Machackova M., Bencurik V., Uluk D., Pratschke J., Dittrich L. S., Guel-Klein S., Perez D., Grass J. -K., Melling N., Mueller S., Iversen L. H., Eriksen J. D., Baatrup G., Al-Najami I., Bjorsum-Meyer T., Teras J., Teras R. M., Monib F. A., Ahmed N. E. A. E., Alkady E., Ali A. K., Khedr G. A. E., Abdelaal A. S., Ashoush F. M. B., Ewedah M., Elshennawy E. M., Hussein M., Fernandez-Martinez D., Garcia-Florez L. J., Fernandez-Hevia M., Suarez-Sanchez A., Aretxabala I. D. H., Docampo I. L., Zabala J. G., Tejedor P., Morales Bernaldo de Quiros J. T., Quiroga I. B., Navarro-Sanchez A., Darias I. S., Fernandez C. L., de La Cruz Cuadrado C., Sanchez-Guillen L., Lopez-Rodriguez-Arias F., Soler-Silva A., Arroyo A., Bernal-Sprekelsen J. C., Gomez-Abril S. A., Gonzalvez P., Torres M. T., Sanchez T. R., Antona F. B., Lara J. E. S., Montero J. A. A., Mendoza-Moreno F., Diez-Alonso M., Matias-Garcia B., Quiroga-Valcarcel A., Colas-Ruiz E., Tasende-Presedo M. M., Fernandez-Hurtado I., Cifuentes-Rodenas J. A., Suarez M. C., Losada M., Hernandez M., Alonso A., Dieguez B., Serralta D., Quintana R. E. M., Lopez J. M. G., Pinto F. L., Nieto-Moreno E., Bonito A. C., Santacruz C. C., Marcos E. B., Septiem J. G., Calero-Lillo A., Alanez-Saavedra J., Munoz-Collado S., Lopez-Lara M., Martinez M. L., Herrero E. F., Borda F. J. G., Villar O. G., Escartin J., Blas J. L., Ferrer R., Egea J. G., Rodriguez-Infante A., Minguez-Ruiz G., Carreno-Villarreal G., Pire-Abaitua G., Dziakova J., Rodriguez C. S. -C., Aranda M. J. P., Huguet J. M. M., Borda-Arrizabalaga N., Enriquez-Navascues J. M., Echaniz G. E., Ansorena Y. S., Estaire-Gomez M., Martinez-Pinedo C., Barbero-Valenzuela A., Ruiz-Garcia P., Kraft M., Gomez-Jurado M. J., Pellino G., Espin-Basany E., Cotte E., Panel N., Goutard C. -A., de Angelis N., Lauka L., Shaikh S., Osborne L., Ramsay G., Nichita V. -I., Bhandari S., Sarmah P., Bethune R. M., Pringle H. C. M., Massey L., Fowler G. E., Hamid H. K. S., de Simone B. D., Kynaston J., Bradley N., Stienstra R. M., Gurjar S., Mukherjee T., Chandio A., Ahmed S., Singh B., Runau F., Chaudhri S., Siaw O., Sarveswaran J., Miu V., Ashmore D., Darwich H., Singh-Ranger D., Singh N., Shaban M., Gareb F., Petropolou T., Polydorou A., Dattani M., Afzal A., Bavikatte A., Sebastian B., Ward N., Mishra A., Manatakis D., Agalianos C., Tasis N., Antonopoulou M. -I., Karavokyros I., Charalabopoulos A., Schizas D., Baili E., Syllaios A., Karydakis L., Vailas M., Balalis D., Korkolis D., Plastiras A., Rompou A., Xenaki S., Xynos E., Chrysos E., Venianaki M., Christodoulidis G., Perivoliotis K., Tzovaras G., Baloyiannis I., Ho M. -F., Ng S. S., Mak T. W. -C., Futaba K., Santak G., Simlesa D., Cosic J., Zukanovic G., Kelly M. E., Larkin J. O., McCormick P. H., Mehigan B. J., Connelly T. M., Neary P., Ryan J., McCullough P., Al-Juaifari M. A., Hammoodi H., Abbood A. H., Calabro M., Muratore A., La Terra A., Farnesi F., Feo C. V., Fabbri N., Pesce A., Fazzin M., Roscio F., Clerici F., Lucchi A., Vittori L., Agostinelli L., Ripoli M. C., Sambucci D., Porta A., Sinibaldi G., Crescentini G., Larcinese A., Picone E., Persiani R., Biondi A., Pezzuto R., Lorenzon L., Rizzo G., Coco C., D'Agostino L., Spinelli A., Sacchi M. M., Carvello M., Foppa C., Maroli A., Palini G. M., Garulli G., Zanini N., Delrio P., Rega D., Carbone F., Aversano A., Pirozzolo G., Recordare A., D'Alimonte L., Vignotto C., Corbellini C., Sampietro G. M., Lorusso L., Manzo C. A., Ghignone F., Ugolini G., Montroni I., Pasini F., Ballabio M., Bisagni P., Armao F. T., Longhi M., Ghazouani O., Galleano R., Tamini N., Oldani M., Nespoli L., Picciariello A., Altomare D. F., Tomasicchio G., Lantone G., Catena F., Giuffrida M., Annicchiarico A., Perrone G., Grossi U., Santoro G. A., Zanus G., Iacomino A., Novello S., Passuello N., Zucchella M., Puca L., deGiuli M., Reddavid R., Scabini S., Aprile A., Soriero D., Fioravanti E., Rottoli M., Romano A., Tanzanu M., Belvedere A., Mariani N. M., Ceretti A. P., Opocher E., Gallo G., Sammarco G., de Paola G., Pucciarelli S., Marchegiani F., Spolverato G., Buzzi G., Di Saverio S., Meroni P., Parise C., Bottazzoli E. I., Lapolla P., Brachini G., Cirillo B., Mingoli A., Sica G., Siragusa L., Bellato V., Cerbo D., de Pasqual C. A., de Manzoni G., di Cosmo M. A., Alrayes B. M. H., Qandeel M. W. M., Hani M. B., Rabadi A., el Muhtaseb M. S., Abdeen B., Karmi F., Zilinskas J., Latkauskas T., Tamelis A., Pikuniene I., Slenfuktas V., Poskus T., Kryzauskas M., Jakubauskas M., Mikalauskas S., Jakubauskiene L., Hassan S. Y., Altrabulsi A., Abdulwahed E., Ghmagh R., Deeknah A., Alshareea E., Elhadi M., Abujamra S., Msherghi A. A., Tababa O. W. E., Majbar M. A., Souadka A., Benkabbou A., Mohsine R., Echiguer S., Moctezuma-Velazquez P., Salgado-Nesme N., Vergara-Fernandez O., Sainz-Hernandez J. C., Alvarez-Bautista F. E., Zakaria A. D., Zakaria Z., Wong M. P. K., Ismail R., Ibrahim A. F., Abdullah N. A. N., Julaihi R., Bhat S., O'Grady G., Bissett I., Lamme B., Musters G. D., Dinaux A. M., Grotenhuis B. A., Steller E. J., Aalbers A. G. J., Leeuwenburgh M. M., Rutten H. J. T., Burger J. W. A., Bloemen J. G., Ketelaers S. H. J., Waqar U., Chawla T., Rauf H., Rani P., Talsma A. K., Scheurink L., van Praagh J. B., Segelman J., Nygren J., Anderin K., Tiefenthal M., de Andres B., Beltran de Heredia J. P., Vazquez A., Gomez T., Golshani P., Kader R., Mohamed A., Westerterp M., Marinelli A., Niemer Q., Doornebosch P. G., Shapiro J., Vermaas M., de Graaf E. J. R., van Westreenen H. L., Zwakman M., van Dalsen A. D., Vles W. J., Nonner J., Toorenvliet B. R., Janssen P. T. J., Verdaasdonk E. G. G., Amelung F. J., Peeters K. C. M. J., Bahadoer R. R., Holman F. A., Heemskerk J., Vosbeek N., Leijtens J. W. A., Taverne S. B. M., Heijnen B. H. M., El-Massoudi Y., de Groot-Van Veen I., Hoff C., Jou-Valencia D., Consten E. C. J., Burghgraef T. A., Geitenbeek R., Hulshof L. G. W. L., Slooter G. D., Reudink M., Bouvy N. D., Wildeboer A. C. L., Verstappen S., Pennings A. J., van den Hengel B., Wijma A. G., de Haan J., de Nes L. C. F., Heesink V., Karsten T., Heidsma C. M., Koemans W. J., Dekker J. -W. T., van der Zijden C. J., Roos D., Demirkiran A., van der Burg S., Oosterling S. J., Hoogteijling T. J., Wiering B., Smeeing D. P. J., Havenga K., Lutfi H., Tsimogiannis K., Skoldberg F., Folkesson J., den Boer F., van Schaik T. G., van Gerven P., Sietses C., Hol J. C., Boerma E. -J. G., Creemers D. M. J., Schultz J. K., Frivold T., Riis R., Gregussen H., Busund S., Sjo O. H., Gaard M., Krohn N., Ersryd A. L., Leung E., Sultan H., Hajjaj B. N., Alhisi A. J., Khader A. A. E., Mendes A. F. D., Semiao M., Faria L. Q., Azevedo C., da Costa Devesa H. M., Martins S. F., Jarimba A. M. R., Marques S. M. R., Ferreira R. M., Oliveira A., Ferreira C., Pereira R., Surlin V. M., Graure G. M., Ramboiu S. P. S. D., Negoi I., Ciubotaru C., Stoica B., Tanase I., Negoita V. M., Florea S., Macau F., Vasile M., Stefanescu V., Dimofte G. -M., Lunca S., Roata C. -E., Musina A. -M., Garmanova T., Agapov M. N., Markaryan D. G., Eduard G., Yanishev A., Abelevich A., Bazaev A., Rodimov S. V., Filimonov V. B., Melnikov A. A., Suchkov I. A., Drozdov E. S., Kostromitskiy D. N., Sjostrom O., Matthiessen P., Baban B., Gadan S., Jadid K. D., Staffan M., Park J. M., Rydbeck D., Lydrup M. -L., Buchwald P., Jutesten H., Darlin L., Lindqvist E., Nilsson K., Larsson P. -A., Jangmalm S., Kosir J. A., Tomazic A., Grosek J., Bozic T. K., Zazo A., Zazo R., Fares H., Ayoub K., Niazi A., Mansour A., Abbas A., Tantoura M., Hamdan A., Hassan N., Hasan B., Saad A., Sebai A., Haddad A., Maghrebi H., Kacem M., Yalkin O., Samsa M. V., Atak I., Balci B., Haberal E., Dogan L., Gecim I. E., Akyol C., Koc M. A., Sivrikoz E., Piyadeoglu D., Avanagh D. O., Sokmen S., Bisgin T., Gunenc E., Guzel M., Leventoglu S., Yuksel O., Kozan R., Gobut H., Cengiz F., Erdinc K., Acar N. C., Kamer E., Ozgur I., Aydin O., Keskin M., Bulut M. T., Kulle C. B., Kara Y., Sibic O., Ozata I. H., Bugra D., Balik E., Cakir M., Alhardan A., Colak E., Aybar A. B. C., Sari A. C., Atici S. D., Kaya T., Dursun A., Calik B., Ozkan O. F., Ulgur H. S., Duzgun O., Monson J., George S., Woods K., Al-Eryani F., Albakry R., Coetzee E., Boutall A., Herman A., Warden C., Mugla N., Forgan T., Mia I., and Lambrechts A.
Abstract: Background: The optimal treatment of anastomotic leak after rectal cancer resection is unclear. This worldwide cohort study aimed to provide an overview of four treatment strategies applied. Methods: Patients from 216 centres and 45 countries with anastomotic leak after rectal cancer resection between 2014 and 2018 were included. Treatment was categorized as salvage surgery, faecal diversion with passive or active (vacuum) drainage, and no primary/secondary faecal diversion. The primary outcome was 1-year stoma-free survival. In addition, passive and active drainage were compared using propensity score matching (2: 1). Results: Of 2470 evaluable patients, 388 (16.0 per cent) underwent salvage surgery, 1524 (62.0 per cent) passive drainage, 278 (11.0 per cent) active drainage, and 280 (11.0 per cent) had no faecal diversion. One-year stoma-free survival rates were 13.7, 48.3, 48.2, and 65.4 per cent respectively. Propensity score matching resulted in 556 patients with passive and 278 with active drainage. There was no statistically significant difference between these groups in 1-year stoma-free survival (OR 0.95, 95 per cent c.i. 0.66 to 1.33), with a risk difference of -1.1 (95 per cent c.i. -9.0 to 7.0) per cent. After active drainage, more patients required secondary salvage surgery (OR 2.32, 1.49 to 3.59), prolonged hospital admission (an additional 6 (95 per cent c.i. 2 to 10) days), and ICU admission (OR 1.41, 1.02 to 1.94). Mean duration of leak healing did not differ significantly (an additional 12 (-28 to 52) days). Conclusion: Primary salvage surgery or omission of faecal diversion likely correspond to the most severe and least severe leaks respectively. In patients with diverted leaks, stoma-free survival did not differ statistically between passive and active drainage, although the increased risk of secondary salvage surgery and ICU admission suggests residual confounding.
Published: 2023

6. The Association of Olfactory Function with BMI, Appetite, and Prospective Weight Change in Dutch Community-Dwelling Older Adults

Author: Fluitman, K. S., Nadar, H. J., Roos, D. S., Berendse, H. W., Keijser, B. J. F., Nieuwdorp, M., Ijzerman, R. G., and Visser, M.
Published: 2019
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7. Medical emergencies at sea: an analysis of ambulance-supported and autonomously performed operations by lifeboat crews

Author: Messelink, Daphne M., primary, van der Ploeg, Gert-Jan, additional, van der Linden, Theo, additional, Flameling, Roos D., additional, and Bierens, Joost J. L. M., additional
Published: 2023
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8. Subcellular Localization of Acetyl-CoA Carboxylase in the Apicomplexan Parasite Toxoplasma gondii

Author: Jelenska, J., Crawford, M. J., Harb, O. S., Zuther, E., Haselkorn, R., Roos, D. S., and Gornicki, P.
Published: 2001

9. De eerste lijn van verdediging: aangeboren immuniteit

Author: Roos, D., Rijkers, G.T., editor, Kroese, F.G.M., editor, Kallenberg, C.G.M., editor, and Derksen, R.H.W.M., editor
Published: 2016
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10. Nationwide Validation of the 8th American Joint Committee on Cancer TNM Staging System and Five Proposed Modifications for Resected Pancreatic Cancer

Author: Schouten, T.J., Daamen, L.A., Dorland, G., Roessel, S.R. van, Groot, V.P., Besselink, M.G., Bonsing, B.A., Bosscha, K., Brosens, L.A.A., Busch, O.R., Dam, R.M. van, Sarasqueta, A.F., Festen, S., Koerkamp, B.G., Harst, E. van der, Hingh, I.H.J.T. de, Intven, M., Kazemier, G., Meijer, V.E. de, Nieuwenhuijs, V.B., Raicu, G.M., Roos, D., Schreinemakers, J.M.J., Stommel, M.W.J., Velthuysen, M.F. van, Verdonk, R.C., Verheij, J., Verkooijen, H.M., Santvoort, H.C. van, Molenaar, I.Q., Dutch Pancreatic Canc Grp, Surgery, Pathology, CCA - Imaging and biomarkers, Amsterdam Gastroenterology Endocrinology Metabolism, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, MUMC+: MA Heelkunde (9), Epidemiologie, Groningen Institute for Organ Transplantation (GIOT), and Center for Liver, Digestive and Metabolic Diseases (CLDM)
Subjects: EDITION, OUTCOMES, Survival, Ductal adenocarcinoma, SURGERY, Nodes, Number, Prognosis, United States, Pancreatic Neoplasms, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], All institutes and research themes of the Radboud University Medical Center, Oncology, SDG 3 - Good Health and Well-being, Tumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14], Humans, Prospective Studies, Carcinoma, Pancreatic Ductal, Neoplasm Staging
Abstract: Background The prognostic value of four proposed modifications to the 8th American Joint Committee on Cancer (AJCC) TNM staging system has yet to be evaluated. This study aimed to validate five proposed modifications. Methods Patients who underwent pancreatic ductal adenocarcinoma resection (2014–2016), as registered in the prospective Dutch Pancreatic Cancer Audit, were included. Stratification and prognostication of TNM staging systems were assessed using Kaplan–Meier curves, Cox proportional hazard analyses, and C-indices. A new modification was composed based on overall survival (OS). Results Overall, 750 patients with a median OS of 18 months (interquartile range 10–32) were included. The 8th edition had an increased discriminative ability compared with the 7th edition {C-index 0.59 (95% confidence interval [CI] 0.56–0.61) vs. 0.56 (95% CI 0.54–0.58)}. Although the 8th edition showed a stepwise decrease in OS with increasing stage, no differences could be demonstrated between all substages; stage IIA vs. IB (hazard ratio [HR] 1.30, 95% CI 0.80–2.09; p = 0.29) and stage IIB vs. IIA (HR 1.17, 95% CI 0.75–1.83; p = 0.48). The four modifications showed comparable prognostic accuracy (C-index 0.59–0.60); however, OS did not differ between all modified TNM stages (ns). The new modification, migrating T3N1 patients to stage III, showed a C-index of 0.59, but did detect significant survival differences between all TNM stages (p Conclusions The 8th TNM staging system still lacks prognostic value for some categories of patients, which was not clearly improved by four previously proposed modifications. The modification suggested in this study allows for better prognostication in patients with all stages of disease.
Published: 2022
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11. Impact of complications after resection of pancreatic cancer on disease recurrence and survival, and mediation effect of adjuvant chemotherapy: nationwide, observational cohort study.

Author: Henry, A.C., Dongen, J.C. van, Goor, I.W.J.M. van, Smits, F.J., Nagelhout, A., Besselink, M.G., Busch, O.R., Bonsing, B.A., Bosscha, K., Dam, R.M. van, Festen, S., Groot Koerkamp, B., Harst, E, Hingh, I.H.J.T. de, Kolk, M. van der, Liem, M.S., Meijer, V.E. de, Patijn, G.A., Roos, D., Schreinemakers, J.M.J., Wit, F., Daamen, L.A., Santvoort, H.C. van, Molenaar, I.Q., Eijck, C.H.J. van, Henry, A.C., Dongen, J.C. van, Goor, I.W.J.M. van, Smits, F.J., Nagelhout, A., Besselink, M.G., Busch, O.R., Bonsing, B.A., Bosscha, K., Dam, R.M. van, Festen, S., Groot Koerkamp, B., Harst, E, Hingh, I.H.J.T. de, Kolk, M. van der, Liem, M.S., Meijer, V.E. de, Patijn, G.A., Roos, D., Schreinemakers, J.M.J., Wit, F., Daamen, L.A., Santvoort, H.C. van, Molenaar, I.Q., and Eijck, C.H.J. van
Abstract: Item does not contain fulltext, BACKGROUND: The causal pathway between complications after pancreatic cancer resection and impaired long-term survival remains unknown. The aim of this study was to investigate the impact of complications after pancreatic cancer resection on disease-free interval and overall survival, with adjuvant chemotherapy as a mediator. METHODS: This observational study included all patients undergoing pancreatic cancer resection in the Netherlands (2014-2017). Clinical data were extracted from the prospective Dutch Pancreatic Cancer Audit. Recurrence and survival data were collected additionally. In causal mediation analysis, direct and indirect effect estimates via adjuvant chemotherapy were calculated. RESULTS: In total, 1071 patients were included. Major complications (hazards ratio 1.22 (95 per cent c.i. 1.04 to 1.43); P = 0.015 and hazards ratio 1.25 (95 per cent c.i. 1.08 to 1.46); P = 0.003) and organ failure (hazards ratio 1.86 (95 per cent c.i. 1.32 to 2.62); P < 0.001 and hazards ratio 1.89 (95 per cent c.i. 1.36 to 2.63); P < 0.001) were associated with shorter disease-free interval and overall survival respectively. The effects of major complications and organ failure on disease-free interval (-1.71 (95 per cent c.i. -2.27 to -1.05) and -3.05 (95 per cent c.i. -4.03 to -1.80) respectively) and overall survival (-1.92 (95 per cent c.i. -2.60 to -1.16) and -3.49 (95 per cent c.i. -4.84 to -2.03) respectively) were mediated by adjuvant chemotherapy. Additionally, organ failure directly affected disease-free interval (-5.38 (95 per cent c.i. -9.27 to -1.94)) and overall survival (-6.32 (95 per cent c.i. -10.43 to -1.99)). In subgroup analyses, the association was found in patients undergoing pancreaticoduodenectomy, but not in patients undergoing distal pancreatectomy. CONCLUSION: Major complications, including organ failure, negatively impact survival in patients after pancreatic cancer resection, largely mediated by adjuvant chemotherapy. Prevention or adequate trea
Published: 2023

12. Practice variation in venous resection during pancreatoduodenectomy for pancreatic cancer: A nationwide cohort study.

Author: Groen, J.V., Michiels, N., Besselink, M.G., Bosscha, K., Busch, O.R., Dam, R. van, Eijck, C.H.J. van, Koerkamp, B.G., Harst, E. van der, Hingh, I.H. de, Karsten, T.M., Lips, D.J., Meijer, V.E. de, Molenaar, I.Q., Nieuwenhuijs, V.B., Roos, D., Santvoort, H.C. van, Wijsman, J.H., Wit, F., Zonderhuis, B.M., Vos-Geelen, J. de, Wasser, M.N., Bonsing, B.A., Stommel, M.W.J., Mieog, J.S.D., Groen, J.V., Michiels, N., Besselink, M.G., Bosscha, K., Busch, O.R., Dam, R. van, Eijck, C.H.J. van, Koerkamp, B.G., Harst, E. van der, Hingh, I.H. de, Karsten, T.M., Lips, D.J., Meijer, V.E. de, Molenaar, I.Q., Nieuwenhuijs, V.B., Roos, D., Santvoort, H.C. van, Wijsman, J.H., Wit, F., Zonderhuis, B.M., Vos-Geelen, J. de, Wasser, M.N., Bonsing, B.A., Stommel, M.W.J., and Mieog, J.S.D.
Abstract: Contains fulltext : 296781.pdf (Publisher’s version ) (Open Access), BACKGROUND: Practice variation exists in venous resection during pancreatoduodenectomy, but little is known about the potential causes and consequences as large studies are lacking. This study explores the potential causes and consequences of practice variation in venous resection during pancreatoduodenectomy for pancreatic cancer in the Netherlands. METHODS: This nationwide retrospective cohort study included patients undergoing pancreatoduodenectomy for pancreatic cancer in 18 centers from 2013 through 2017. RESULTS: Among 1,311 patients undergoing pancreatoduodenectomy, 351 (27%) had a venous resection, and the overall median annual center volume of venous resection was 4. No association was found between the center volume of pancreatoduodenectomy and the rate of venous resections, nor between patient and tumor characteristics and the rate of venous resections per center. Female sex, lower body mass index, neoadjuvant therapy, venous involvement, and stenosis on imaging were predictive for venous resection. Adjusted for these factors, 3 centers performed significantly more, and 3 centers performed significantly fewer venous resections than expected. In patients with venous resection, significantly less major morbidity (22% vs 38%) and longer overall survival (median 16 vs 12 months) were observed in centers with an above-median annual volume of venous resections (>4). CONCLUSION: Patient and tumor characteristics did not explain significant practice variation between centers in the Netherlands in venous resection during pancreatoduodenectomy for pancreatic cancer. The clinical outcomes of venous resection might be related to the volume of the procedure.
Published: 2023

13. Risk Models for Developing Pancreatic Fistula After Pancreatoduodenectomy: Validation in a Nationwide Prospective Cohort.

Author: Schouten, T.J., Henry, A.C., Smits, F.J., Besselink, M.G., Bonsing, B.A., Bosscha, K., Busch, O.R., Dam, R.M. van, Eijck, C.H.J. van, Festen, S., Groot Koerkamp, B., Harst, E. van der, Hingh, I.H.J.T. de, Kazemier, G., Liem, M.S.L., Meijer, V.E. de, Patijn, G.A., Roos, D., Schreinemakers, J.M.J., Stommel, M.W.J., Wit, F., Daamen, L.A., Molenaar, I.Q., Santvoort, H.C. van, Schouten, T.J., Henry, A.C., Smits, F.J., Besselink, M.G., Bonsing, B.A., Bosscha, K., Busch, O.R., Dam, R.M. van, Eijck, C.H.J. van, Festen, S., Groot Koerkamp, B., Harst, E. van der, Hingh, I.H.J.T. de, Kazemier, G., Liem, M.S.L., Meijer, V.E. de, Patijn, G.A., Roos, D., Schreinemakers, J.M.J., Stommel, M.W.J., Wit, F., Daamen, L.A., Molenaar, I.Q., and Santvoort, H.C. van
Abstract: Item does not contain fulltext, OBJECTIVE: To evaluate the performance of published fistula risk models by external validation, and to identify independent risk factors for postoperative pancreatic fistula (POPF). BACKGROUND: Multiple risk models have been developed to predict POPF after pancreatoduodenectomy. External validation in high-quality prospective cohorts is, however, lacking or only performed for individual models. METHODS: A post hoc analysis of data from the stepped-wedge cluster cluster-randomized Care After Pancreatic Resection According to an Algorithm for Early Detection and Minimally Invasive Management of Pancreatic Fistula versus Current Practice (PORSCH) trial was performed. Included were all patients undergoing pancreatoduodenectomy in the Netherlands (January 2018-November 2019). Risk models on POPF were identified by a systematic literature search. Model performance was evaluated by calculating the area under the receiver operating curves (AUC) and calibration plots. Multivariable logistic regression was performed to identify independent risk factors associated with clinically relevant POPF. RESULTS: Overall, 1358 patients undergoing pancreatoduodenectomy were included, of whom 341 patients (25%) developed clinically relevant POPF. Fourteen risk models for POPF were evaluated, with AUCs ranging from 0.62 to 0.70. The updated alternative fistula risk score had an AUC of 0.70 (95% confidence intervals [CI]: 0.69-0.72). The alternative fistula risk score demonstrated an AUC of 0.70 (95% CI: 0.689-0.71), whilst an AUC of 0.70 (95% CI: 0.699-0.71) was also found for the model by Petrova and colleagues. Soft pancreatic texture, pathology other than pancreatic ductal adenocarcinoma or chronic pancreatitis, small pancreatic duct diameter, higher body mass index, minimally invasive resection and male sex were identified as independent predictors of POPF. CONCLUSION: Published risk models predicting clinically relevant POPF after pancreatoduodenectomy have a moderate predictive accur
Published: 2023

14. Calibration approaches in Multi-Node Antenna Characterization Setups

Author: Coesoij, R.A. (author), Musters, F.A. (author), Roos, D. (author), van Velden, T. (author), Spirito, M. (author), Coesoij, R.A. (author), Musters, F.A. (author), Roos, D. (author), van Velden, T. (author), and Spirito, M. (author)
Abstract: In this work we present calibration approaches aimed at mitigating the measurement error in testbenches featuring multiple sensor-nodes and operating over-the-air. Such errors can arise from fluctuations in component responses and mechanical tolerances of the setup. The calibration approaches are detailed for the case of the Antenna Dome measurement setup previously presented by the authors.In the current implementation, the Antenna Dome employs multiple dual linearly-polarized scalar sensing nodes, to enable real-time 2D (theta and phi) radiation pattern acquisition. The variation of the electrical response among the different sensing elements as well as their position, with respect to the nominal one, due to the mechanical tolerances, introduce systematic error in the generated radiation patterns.Over-the-air procedures to linearize the power conversion asymmetry within the dually polarized nodes as well as the linearity response across them are described. Proposed approach provides a reduction of the angular dependent error within ±0.5 dB across the various nodes. Moreover, to minimize the impact of mechanical deviations an over-the-air method is described to transfer the sensor coordinates from the mechanical reference system to the antenna under test one., Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public., Electronics
Published: 2023
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15. PD-0081 Research culture in Australian and New Zealand radiation oncology: fact or fantasy?

Author: Roos, D., primary
Published: 2023
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16. OC-0437 Mature outcomes for TROG 99.03: RCT of RT +/- (R)-CVP in Stage I-II Follicular Lymphoma

Author: MacManus, M., primary, Seymour, J., additional, Roos, D., additional, O'Brien, P., additional, Macann, A., additional, Tsang, R., additional, Davis, S., additional, Shrestha, S., additional, Joseph, D., additional, Gandhi, M., additional, and Tobin, J., additional
Published: 2023
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17. Short- and Long-Term Outcomes of Pancreatic Cancer Resection in Elderly Patients: A Nationwide Analysis

Author: Henry, A.C., Schouten, T.J., Daamen, L.A., Walma, M.S., Noordzij, P., Cirkel, G.A., Los, M., Besselink, M.G.H., Busch, O.R., Bonsing, B.A., Bosscha, K., Dam, R.M. van, Festen, S., Koerkamp, B. Groot, Harst, E, Hingh, I. de, Kazemier, G., Liem, M.S., Meijer, V.E. de, Nieuwenhuijs, V.B., Roos, D., Schreinemakers, J.M.J., Stommel, M.W.J., Molenaar, I.Q., Santvoort, H.C. van, Surgery, MUMC+: MA Heelkunde (9), RS: NUTRIM - R2 - Liver and digestive health, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, CCA - Cancer Treatment and Quality of Life, Amsterdam Gastroenterology Endocrinology Metabolism, Groningen Institute for Organ Transplantation (GIOT), Center for Liver, Digestive and Metabolic Diseases (CLDM), and CCA - Cancer Treatment and quality of life
Subjects: CHRONIC KIDNEY-DISEASE, RISK, MORTALITY, OCTOGENARIANS, DUCTAL ADENOCARCINOMA, CHEMOTHERAPY, Pancreatic Hormones, Pancreatic Neoplasms, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], Pancreatectomy, AGE, SDG 3 - Good Health and Well-being, Oncology, Chemotherapy, Adjuvant, PANCREATICODUODENECTOMY, Humans, Surgery, Prospective Studies, POSTOPERATIVE COMPLICATIONS, FRAILTY, Aged, Retrospective Studies
Abstract: Background The number of elderly patients with pancreatic cancer is growing, however clinical data on the short-term outcomes, rate of adjuvant chemotherapy, and survival in these patients are limited and we therefore performed a nationwide analysis. Methods Data from the prospective Dutch Pancreatic Cancer Audit were analyzed, including all patients undergoing pancreatic cancer resection between January 2014 and December 2016. Patients were classified into two age groups: Results Of 836 patients, 198 were aged ≥75 years (24%) and 638 were aged p = 0.43) and 90-day mortality (8% vs. 5%; p = 0.18) did not differ. Adjuvant chemotherapy was started in 37% of patients aged ≥75 years versus 69% of patients aged p < 0.001). Median overall survival (OS) was 15 months (95% confidence interval [CI] 14–18) versus 21 months (95% CI 19–24; p < 0.001). Age ≥75 years was not independently associated with OS (hazard ratio 0.96, 95% CI 0.79–1.17; p = 0.71), but was associated with a lower rate of adjuvant chemotherapy (odds ratio 0.27, 95% CI 0.18–0.40; p < 0.001). Conclusions The rate of major complications and 90-day mortality after pancreatic resection did not differ between elderly and younger patients; however, elderly patients were less often treated with adjuvant chemotherapy and their OS was shorter.
Published: 2022
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18. Venous wedge and segment resection during pancreatoduodenectomy for pancreatic cancer

Author: Groen, J.V., Michiels, N., Roessel, S. van, Besselink, M.G., Bosscha, K., Busch, O.R., Dam, R. van, Eijck, C.H.J. van, Koerkamp, B.G., Harst, E. van der, Hingh, I.H. de, Karsten, T.M., Lips, D.J., Meijer, V.E. de, Molenaar, I.Q., Nieuwenhuijs, V.B., Roos, D., Santvoort, H.C. van, Wijsman, J.H., Wit, F., Zonderhuis, B.M., Vos-Geelen, J. de, Wasser, M.N., Bonsing, B.A., Stommel, M.W.J., Mieog, J.S.D., Dutch Pancreatic Canc Grp, Surgery, MUMC+: MA Heelkunde (9), RS: NUTRIM - R2 - Liver and digestive health, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Epidemiologie, Interne Geneeskunde, MUMC+: MA Medische Oncologie (9), Groningen Institute for Organ Transplantation (GIOT), Center for Liver, Digestive and Metabolic Diseases (CLDM), AGEM - Re-generation and cancer of the digestive system, CCA - Cancer Treatment and quality of life, CCA - Cancer Treatment and Quality of Life, and AGEM - Amsterdam Gastroenterology Endocrinology Metabolism
Subjects: Male, medicine.medical_specialty, SURGERY, INTERNATIONAL STUDY-GROUP, CONSENSUS STATEMENT, ALLOGRAFT, GUIDELINES, CLASSIFICATION, Pancreaticoduodenectomy, Resection, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], Mesenteric Veins, SDG 3 - Good Health and Well-being, Pancreatic cancer, medicine, Long term outcomes, Humans, In patient, Pancreas, Aged, Retrospective Studies, Portal Vein, business.industry, MORTALITY, VEIN RECONSTRUCTION, Retrospective cohort study, Middle Aged, medicine.disease, Survival Analysis, Surgery, Pancreatic Neoplasms, Treatment Outcome, DEFINITION, OPERATION, Female, Segmental resection, business, Wedge resection (lung), Cohort study
Abstract: Background Venous resection of the superior mesenteric or portal vein is increasingly performed in pancreatic cancer surgery, whereas results of studies on short- and long-term outcomes are contradictory. The aim of this study was to evaluate the impact of the type of venous resection in pancreatoduodenectomy for pancreatic cancer on postoperative morbidity and overall survival. Methods This nationwide retrospective cohort study included all patients who underwent pancreatoduodenectomy for pancreatic cancer in 18 centres (2013-2017). Results A total of 1311 patients were included, of whom 17 per cent underwent wedge resection and 10 per cent segmental resection. Patients with segmental resection had higher rates of major morbidity (39 versus 20 versus 23 per cent, respectively; P < 0.001) and portal or superior mesenteric vein thrombosis (18 versus 5 versus 1 per cent, respectively; P < 0.001) and worse overall survival (median 12 versus 16 versus 20 months, respectively; P < 0.001), compared to patients with wedge resection and those without venous resection. Multivariable analysis showed patients with segmental resection, but not those who had wedge resection, had higher rates of major morbidity (odds ratio = 1.93, 95 per cent c.i. 1.20 to 3.11) and worse overall survival (hazard ratio = 1.40, 95 per cent c.i. 1.10 to 1.78), compared to patients without venous resection. Among patients who received neoadjuvant therapy, there was no difference in overall survival among patients with segmental and wedge resection and those without venous resection (median 32 versus 25 versus 33 months, respectively; P = 0.470), although there was a difference in major morbidity rates (52 versus 19 versus 21 per cent, respectively; P = 0.012). Conclusion In pancreatic surgery, the short- and long-term outcomes are worse in patients with venous segmental resection, compared to patients with wedge resection and those without venous resection.Of 1311 patients who underwent pancreatoduodenectomy, 17 per cent underwent venous wedge resection and 10 per cent underwent venous segmental resection. Venous segmental, but not venous wedge, resection was associated with higher major morbidity rates (odds ratio = 1.93, 95 per cent c.i. 1.20 to 3.11) and worse overall survival (hazard ratio = 1.40, 95 per cent c.i. 1.10 to 1.78), compared to no venous resection. This nationwide study found worse short- and long-term outcomes in patients who had venous segmental resection. The results of this study urge the need for improving outcomes in patients who require venous segmental resection.
Published: 2022
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19. 34 Transurethrale microgolfthermotherapie (TUMT)

Author: Roos, D., Bosch, J.L.H.R., editor, and Prins, A., editor
Published: 2010
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20. Temporal and inter-specific variations in forage fish feeding conditions in the NW Mediterranean : lipid content and fatty acid compositional changes

Author: Pethybridge, H., Bodin, N., Arsenault-Pernet, E.-J., Bourdeix, J.-H., Brisset, B., Bigot, J.-L., Roos, D., and Peter, M.
Published: 2014

21. Responses of European anchovy vital rates and population growth to environmental fluctuations: An individual-based modeling approach

Author: Pethybridge, H., Roos, D., Loizeau, V., Pecquerie, L., and Bacher, C.
Published: 2013
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22. Trophic structure in the Gulf of Lions marine ecosystem (north-western Mediterranean Sea) and fishing impacts

Author: Bănaru, D., Mellon-Duval, C., Roos, D., Bigot, J.-L., Souplet, A., Jadaud, A., Beaubrun, P., and Fromentin, J.-M.
Published: 2013
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23. Microscopic resection margin status in pancreatic ductal adenocarcinoma - A nationwide analysis

Author: Daamen, L.A., Goor, I.W.J.M. van, Schouten, T.J., Dorland, G., Roessel, S.R. van, Besselink, M.G., Bonsing, B.A., Bosscha, K., Brosens, L.A.A., Busch, O.R., Dam, R.M. van, Sarasqueta, A.F., Festen, S., Koerkamp, B.G., Harst, E. van der, Hingh, I.H.J.T. de, Intven, M.P.W., Kazemier, G., Meijer, V.E. de, Nieuwenhuijs, V.B., Raicu, G.M., Roos, D., Schreinemakers, J.M.J., Stommel, M.W.J., Velthuysen, M.F. van, Verheij, J., Verkooijen, H.M., Santvoort, H.C. van, Molenaar, I.Q., Dutch Pancreatic Canc Grp, Graduate School, CCA - Cancer Treatment and Quality of Life, Surgery, CCA - Imaging and biomarkers, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Pathology, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, RS: NUTRIM - R2 - Liver and digestive health, MUMC+: MA Heelkunde (9), CCA - Cancer Treatment and quality of life, Groningen Institute for Organ Transplantation (GIOT), and Center for Liver, Digestive and Metabolic Diseases (CLDM)
Subjects: Male, medicine.medical_specialty, Pancreatic ductal adenocarcinoma, 030230 surgery, Disease-Free Survival, Resection, Cohort Studies, 03 medical and health sciences, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], 0302 clinical medicine, All institutes and research themes of the Radboud University Medical Center, SDG 3 - Good Health and Well-being, Margin (machine learning), Pancreatic cancer, medicine, Overall survival, Tumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14], Humans, Aged, Netherlands, Proportional Hazards Models, business.industry, Margins of Excision, General Medicine, Margin involvement, Middle Aged, medicine.disease, Prognosis, Pancreatic Neoplasms, Survival Rate, Logistic Models, Oncology, 030220 oncology & carcinogenesis, Multivariate Analysis, Resection margin, Surgery, Female, Radiology, business, Cohort study, Carcinoma, Pancreatic Ductal
Abstract: Introduction: First, this study aimed to assess the prognostic value of different definitions for resection margin status on disease-free survival (DFS) and overall survival (OS) in pancreatic ductal adenocarcinoma (PDAC). Second, preoperative predictors of direct margin involvement were identified.Materials and methods: This nationwide observational cohort study included all patients who underwent upfront PDAC resection (2014-2016), as registered in the prospective Dutch Pancreatic Cancer Audit. Patients were subdivided into three groups: R0 (>= 1 mm margin clearance), R1 (= 1 mm) was achieved in 277 patients (47%), R1 (= 1 mm) (hazard ratio (HR) 1.35 [95% and confidence interval (CI) 1.08-1.70); P < 0.01) and R1 (= 1 mm) and R1 (1 mm. Given that any vascular tumour involvement on preoperative imaging was associated with an increased risk of R1 (direct) resection with upfront surgery, neoadjuvant therapy might be considered in these patients. (C) 2020 Published by Elsevier Ltd.
Published: 2021
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24. Nationwide Validation of the 8th American Joint Committee on Cancer TNM Staging System and Five Proposed Modifications for Resected Pancreatic Cancer (Apr, 10.1245/s10434-022-11664-4, 2022)

Author: Schouten, T.J., Daamen, L.A., Dorland, G., Roessel, S.R. van, Groot, V.P., Besselink, M.G., Bonsing, B.A., Bosscha, K., Brosens, L.A.A., Busch, O.R., Dam, R.M. van, Sarasqueta, A.F., Festen, S., Koerkamp, B.G., Harst, E. van der, Hingh, I.H.J.T. de, Intven, M., Kazemier, G., Meijer, V.E. de, Nieuwenhuijs, V.B., Raicu, G.M., Roos, D., Schreinemakers, J.M.J., Stommel, M.W.J., Velthuysen, M.F. van, Verdonk, R.C., Verheij, J., Verkooijen, H.M., Santvoort, H.C. van, Molenaar, I.Q., and Dutch Pancreatic Canc Grp
Published: 2022

25. The Effects of Self-Monitoring Using a Smartwatch and Smartphone App on Stress Awareness, Self-Efficacy, and Well-Being–Related Outcomes in Police Officers: Longitudinal Mixed Design Study

Author: Herman Jaap de Vries, Roos Delahaij, Marianne van Zwieten, Helen Verhoef, and Wim Kamphuis
Subjects: Information technology, T58.5-58.64, Public aspects of medicine, RA1-1270
Abstract: Abstract BackgroundWearable sensor technologies, often referred to as “wearables,” have seen a rapid rise in consumer interest in recent years. Initially often seen as “activity trackers,” wearables have gradually expanded to also estimate sleep, stress, and physiological recovery. In occupational settings, there is a growing interest in applying this technology to promote health and well-being, especially in professions with highly demanding working conditions such as first responders. However, it is not clear to what extent self-monitoring with wearables can positively influence stress- and well-being–related outcomes in real-life conditions and how wearable-based interventions should be designed for high-risk professionals. ObjectiveThe aim of this study was to investigate (1) whether offering a 5-week wearable-based intervention improves stress- and well-being–related outcomes in police officers and (2) whether extending a basic “off-the-shelf” wearable-based intervention with ecological momentary assessment (EMA) questionnaires, weekly personalized feedback reports, and peer support groups improves its effectiveness. MethodsA total of 95 police officers from 5 offices participated in the study. The data of 79 participants were included for analysis. During the first 5 weeks, participants used no self-monitoring technology (control period). During the following 5 weeks (intervention period), 41 participants used a Garmin Forerunner 255 smartwatch with a custom-built app (comparable to that of the consumer-available wearable), whereas the other 38 participants used the same system, but complemented by daily EMA questionnaires, weekly personalized feedback reports, and access to peer support groups. At baseline (T0) and after the control (T1) and intervention (T2) periods, questionnaires were administered to measure 15 outcomes relating to stress awareness, stress management self-efficacy, and outcomes related to stress and general well-being. Linear mixed models that accounted for repeated measures within subjects, the control and intervention periods, and between-group differences were used to address both research questions. ResultsThe results of the first analysis showed that the intervention had a small (absolute Hedges g ConclusionsOffering a 5-week wearable-based intervention to police officers can positively contribute to optimizing their stress-related, self-efficacy, and well-being–related outcomes. Complementing the basic “off-the-shelf” wearable-based intervention with additional EMA questionnaires, weekly personalized feedback reports, and peer support groups did not appear to improve the effectiveness of the intervention. Future work is needed to investigate how different aspects of these interventions can be tailored to specific characteristics and needs of employees to optimize these effects.
Published: 2025
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26. A combined experimental and theoretical approach to interpret the anomalous thermal behaviour of Pb-exchanged zeolite (STI)

Author: Cametti, G., primary, Roos, D., additional, Churakov, S.V., additional, Prieur, D., additional, and Scheinost, A.C., additional
Published: 2022
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27. Preoperative predictors for early and very early disease recurrence in patients undergoing resection of pancreatic ductal adenocarcinoma

Author: Daamen, L.A., Dorland, G., Brada, L.J.H., Groot, V.P., Oosten, A.F. van, Besselink, M.G., Bosscha, K., Bonsing, B.A., Busch, O.R., Cirkel, G.A., Dam, R.M. van, Festen, S., Koerkamp, B.G., Mohammad, N.H., Harst, E. van der, Hingh, I.H.J.T. de, Intven, M.P.W., Kazemier, G., M. los, Meijer, V.E. de, Nieuwenhuijs, V.B., Roos, D., Schreinemakers, J.M.J., Stommel, M.W.J., Verdonk, R.C., Verkooijen, H.M., Molenaar, I.Q., Santvoort, H.C. van, Dutch Pancreatic Canc Grp, Surgery, MUMC+: MA Heelkunde (9), RS: NUTRIM - R2 - Liver and digestive health, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, CCA - Imaging and biomarkers, CCA - Cancer Treatment and Quality of Life, Amsterdam Gastroenterology Endocrinology Metabolism, Groningen Institute for Organ Transplantation (GIOT), and Center for Liver, Digestive and Metabolic Diseases (CLDM)
Subjects: medicine.medical_specialty, Pancreatic ductal adenocarcinoma, Early Recurrence, medicine.medical_treatment, THERAPY, Resection, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], ADJUVANT CHEMOTHERAPY, QUALITY-OF-LIFE, Interquartile range, medicine, Overall survival, Humans, In patient, Neoadjuvant therapy, Retrospective Studies, Hepatology, business.industry, Early disease, Gastroenterology, Infant, Prognosis, UPFRONT SURGERY, Surgery, Pancreatic Neoplasms, GEMCITABINE, SURVIVAL, Neoplasm Recurrence, Local, business, Carcinoma, Pancreatic Ductal
Abstract: Contains fulltext : 251552.pdf (Publisher’s version ) (Open Access) BACKGROUND: This study aimed to identify predictors for early and very early disease recurrence in patients undergoing resection of pancreatic ductal adenocarcinoma (PDAC) resection with and without neoadjuvant therapy. METHODS: Included were patients who underwent PDAC resection (2014-2016). Multivariable multinomial regression was performed to identify preoperative predictors for manifestation of recurrence within 3, 6 and 12 months after PDAC resection. RESULTS: 836 patients with a median follow-up of 37 (interquartile range [IQR] 30-48) months and overall survival of 18 (IQR 10-32) months were analyzed. 670 patients (80%) developed recurrence: 82 patients (10%)
Published: 2022

28. Polymorphisms of FcγRIIIa on NK cells and macrophages

Author: Koene, H. R., Von Dem Borne, A. E. G. Kr., Roos, D., de Haas, M., Bird, Graham, editor, Whaley, Keith, editor, van de Winkel, Jan G. J., editor, and Hogarth, P. Mark, editor
Published: 1998
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29. Adult medulloblastoma in an Australian population.

Author: Parakh S., Davies A., Westcott K., Roos D., Abou-Hamden A., Ahern E., Lau P.K.H., Cheruvu S., Pranavan G., Pullar A., Lynam J., Gzell C., Whittle J.R., Cain S., Inglis P.-L., Harrup R., Anazodo A., Hovey E., Cher L., Gan H.K., Parakh S., Davies A., Westcott K., Roos D., Abou-Hamden A., Ahern E., Lau P.K.H., Cheruvu S., Pranavan G., Pullar A., Lynam J., Gzell C., Whittle J.R., Cain S., Inglis P.-L., Harrup R., Anazodo A., Hovey E., Cher L., and Gan H.K.
Abstract: Medulloblastoma in adult patients is a rare condition with limited contemporary demographic and treatment outcome data available in an Australian population. We conducted a retrospective review of patterns of care and outcomes of adult patients diagnosed with medulloblastoma treated at major neuro-oncology centres across Australia between January 2010 and December 2019. A total of 80 patients were identified and the median follow-up after diagnosis was 59.2 (range 0.5-204) months. A variety of chemotherapy regimens were used in the adjuvant and recurrent settings. The median overall survival (mOS) was 78 months (IQR 17.5-94.8). Patients who had no residual disease post-resection or with SHH-subtype tumours had a numerically longer 5-year survival rate than those with residual disease post resection or non-SHH subtypes respectively. The median time to recurrence from diagnosis was 18.4 months. The median OS from 1st relapse was 22.1 months (95% CI 11.7-31.4) and mOS from second relapse was 10.2 months (95% CI 6.6 - NR). This is the largest dataset examining patterns of care of adult patients with medulloblastoma in an Australian population. Substantial variation existed in the chemotherapy agents used in the adjuvant and recurrent setting. As has been demonstrated in a paediatric population, trials such as the upcoming EORTC 1634-BTG/NOA-23 trial (PersoMed-1 study) which are tailoring treatments to molecular profiles are likely to improve outcome in adult medulloblastoma.Copyright © 2022 Elsevier Ltd. All rights reserved.
Published: 2022

30. Impact of Complications After Pancreatoduodenectomy on Mortality, Organ Failure, Hospital Stay, and Readmission: Analysis of a Nationwide Audit

Author: Smits, F.J., Verweij, M.E., Daamen, L.A., Werkhoven, C.H. van, Goense, L., Besselink, M.G.H., Bonsing, B.A., Busch, O.R., Dam, R.M. van, Eijck, C.H.J. van, Festen, S., Koerkamp, B.Groot, Harst, E, Hingh, I.H.J.T. de, Kazemier, G., Klaase, Joost M., Kolk, M. van der, Liem, M., Luyer, M.D., Meerdink, M., Mieog, J.Sven D., Nieuwenhuijs, V.B., Roos, D., Schreinemakers, J.M.J., Stommel, M.W.J., Wit, F., Zonderhuis, B.M., Meijer, V.E. de, Santvoort, H.C. van, Molenaar, I.Q., Smits, F.J., Verweij, M.E., Daamen, L.A., Werkhoven, C.H. van, Goense, L., Besselink, M.G.H., Bonsing, B.A., Busch, O.R., Dam, R.M. van, Eijck, C.H.J. van, Festen, S., Koerkamp, B.Groot, Harst, E, Hingh, I.H.J.T. de, Kazemier, G., Klaase, Joost M., Kolk, M. van der, Liem, M., Luyer, M.D., Meerdink, M., Mieog, J.Sven D., Nieuwenhuijs, V.B., Roos, D., Schreinemakers, J.M.J., Stommel, M.W.J., Wit, F., Zonderhuis, B.M., Meijer, V.E. de, Santvoort, H.C. van, and Molenaar, I.Q.
Abstract: Item does not contain fulltext, OBJECTIVE: To quantify the impact of individual complications on mortality, organ failure, hospital stay, and readmission after pancreatoduodenectomy. SUMMARY OF BACKGROUND DATA: An initial complication may provoke a sequence of adverse events potentially leading to mortality after pancreatoduodenectomy. This study was conducted to aid prioritization of quality improvement initiatives. METHODS: Data from consecutive patients undergoing pancreatoduodenectomy (2014-2017) were extracted from the Dutch Pancreatic Cancer Audit. Population attributable fractions (PAF) were calculated for the association of each complication (ie, postoperative pancreatic fistula, postpancreatectomy hemorrhage, bile leakage, delayed gastric emptying, wound infection, and pneumonia) with each unfavorable outcome [ie, in-hospital mortality, organ failure, prolonged hospital stay (>75th percentile), and unplanned readmission), whereas adjusting for confounders and other complications. The PAF represents the proportion of an outcome that could be prevented if a complication would be eliminated completely. RESULTS: Overall, 2620 patients were analyzed. In-hospital mortality occurred in 95 patients (3.6%), organ failure in 198 patients (7.6%), and readmission in 427 patients (16.2%). Postoperative pancreatic fistula and postpancreatectomy hemorrhage had the greatest independent impact on mortality [PAF 25.7% (95% CI 13.4-37.9) and 32.8% (21.9-43.8), respectively] and organ failure [PAF 21.8% (95% CI 12.9-30.6) and 22.1% (15.0-29.1), respectively]. Delayed gastric emptying had the greatest independent impact on prolonged hospital stay [PAF 27.6% (95% CI 23.5-31.8)]. The impact of individual complications on unplanned readmission was smaller than 11%. CONCLUSION: Interventions focusing on postoperative pancreatic fistula and postpancreatectomy hemorrhage may have the greatest impact on in-hospital mortality and organ failure. To prevent prolonged hospital stay, initiatives should in addition focus
Published: 2022

31. Molecular Genetic Tools for the Identification and Analysis of Drug Targets in Toxoplasma gondii

Author: Roos, D. S., Compans, R. W., editor, Cooper, M., editor, Koprowski, H., editor, Melchers, F., editor, Oldstone, M., editor, Olsnes, S., editor, Potter, M., editor, Saedler, H., editor, Vogt, P. K., editor, Wagner, H., editor, and Gross, Uwe, editor
Published: 1996
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32. Intracavitary Heating Technologies

Author: Roos, D. I., Seegenschmiedt, M. H., Sorbe, B., Seegenschmiedt, M. Heinrich, editor, Fessenden, Peter, editor, and Vernon, Clare C., editor
Published: 1995
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33. OC-0111 Prognostic factors for isolated local recurrence after resection of pancreatic ductal adenocarcinoma

Author: van Goor, I., primary, Nagelhout, A., additional, Besselink, M., additional, Bonsing, B., additional, Bosscha, K., additional, Brosens, L., additional, Busch, O., additional, Cirkel, G., additional, van Dam, R., additional, Festen, S., additional, Groot Koerkamp, B., additional, van der Harst, E., additional, de Hingh, I., additional, Kazemier, G., additional, Meijer, G., additional, de Meijer, V., additional, Nieuwenhuijs, V., additional, Roos, D., additional, Schreinemakers, J., additional, Stommel, M., additional, Verdonk, R., additional, van Santvoort, H., additional, Molenaar, Q., additional, Daamen, L., additional, and Intven, M., additional
Published: 2022
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34. Variation of the relationships between lengths and weights applied to 123 fish species observed at Réunion Island (Indian Ocean)

Author: Roos, D, primary, Taconet, J, additional, Gentil, C, additional, Brisset, B, additional, Evano, H, additional, Aumond, Y, additional, Huet, J, additional, Lepetit, C, additional, Boymond-Morales, R, additional, Rungassamy, T, additional, Elleboode, R, additional, and Mahé, K, additional
Published: 2022
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35. Pbx(OH)y cluster formation in STI framework-type zeolites: anomalous thermal behaviour and increased thermal stability

Author: Cametti, G., Roos, D. P., Churakov, S. V., Prieur, D., and Scheinost, A. C.
Subjects: negative thermal expansion, Zeolite, ROBL
Abstract: The structural modifications occurring in zeolites upon heating are of interest because of technological and industrial applications. In this study, we report the anomalous behaviour of a Pb-exchanged zeolite (Pb13.4(OH)10Al17.4Si54.6O144 ∙38H2O) with STI framework type. For the first time, we observed a switch forom negative to positive thermal expansion during continuous heating. The dehydration was tracked in situ from 25 to 450 °C by single crystal X-ray diffraction, infrared, and X-ray absorption spectroscopy. Furthermore, toTo assist interpretation of the experimental results, molecular dynamics simulations were performed on a series of different theoretical models. Initially, Pb-STI unit-cell volume contracts (ΔV = -3.5%) from 25 to 100°C. This is in line with the trend observed in STI zeolites. Surprisingly, at 125°C, the framework expanded (ΔV = +2%), adopting a configuration, which resembles that of the room temperature structure. Upon heating, the structure loses H2O but no de-hydroxylation occurred. This behaviour is explained via the formation of Pbx(OH)x (x= 2,4) clusters, which prevent the shrinking of the channels, rupture of the tetrahedral bonds and occlusion of the pores. This zeolite has therefore an increased thermal stability with respect to other STI metal-exchanged zeolites, with important consequences foron its applications.
Published: 2022

36. Fcγ Receptors of Myeloid Cells

Author: de Haas, M., Huizinga, T. W. J., van de Winkel, J. G. J., Roos, D., von dem Borne, A. E. G. Kr., Harris, J. R., editor, and Horton, Michael A., editor
Published: 1993
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37. Intracavitary Thermoradiotherapy for Vaginal Carcinoma

Author: Sorbe, B., Roos, D., Smed-Sörensen, C., Frankendal, B., Seegenschmiedt, M. Heinrich, editor, and Sauer, Rolf, editor
Published: 1993
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38. Review of Intracavitary Hyperthermia Techniques

Author: Roos, D., Seegenschmiedt, M. Heinrich, editor, and Sauer, Rolf, editor
Published: 1993
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39. Generation of reactive oxygen species by phagocytes

Author: Roos, D., Bolscher, B. G. J. M., De Boer, M., and van Furth, Ralph, editor
Published: 1992
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40. Membrane surface antigen expression on human monocytes: changes during purification, in vitro activation and transmigration across monolayers of endothelial cells

Author: Kuijpers, T. W., Hakkert, B. C., Knol, E. F., Roos, D., and van Furth, Ralph, editor
Published: 1992
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41. Involvement of ELAM-1 in monocyte adherence to and migration across IL-1-stimulated endothelial cell monolayers

Author: Hakkert, B. C., Kuijpers, T. W., Buurman, W. A., Van Mourik, J. A., Roos, D., and van Furth, Ralph, editor
Published: 1992
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42. Treatment of Recurrence and Post-Recurrence Survival after Different Primary Treatment Strategies for Patients with Pancreatic Cancer

Author: Andel, P., primary, van Goor, I., additional, Besselink, M., additional, Bonsing, B., additional, Bosscha, K., additional, Brosens, L., additional, Busch, O., additional, Cirkel, G., additional, Van Dam, R., additional, Festen, S., additional, Koerkamp, B. Groot, additional, Van der Harst, E., additional, De Hingh, I., additional, Intven, M., additional, Kazemier, G., additional, Los, M., additional, Meijer, G., additional, De Meijer, V., additional, Nieuwenhuijs, V., additional, Roos, D., additional, Schreinemakers, J., additional, Stommel, M., additional, Verdonk, R., additional, Van Santvoort, H., additional, and Molenaar, I., additional
Published: 2022
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43. Prognostic Factors Associated with Long-Term Recurrence-Free Survival after Resection of Pancreatic Ductal Adenocarcinoma (PDAC): A Nationwide Analysis

Author: van Goor, I., primary, Schouten, T., additional, Besselink, M., additional, Bonsing, B., additional, Bosscha, K., additional, Brosens, L., additional, Busch, O., additional, Cirkel, G., additional, van Dam, R., additional, Festen, S., additional, Koerkamp, B. Groot, additional, van der Harst, E., additional, de Hingh, I., additional, Intven, M., additional, Kazemier, G., additional, Los, M., additional, de Meijer, V., additional, Nieuwenhuijs, V., additional, Roos, D., additional, Schreinemakers, J., additional, Stommel, M., additional, Verdonk, R., additional, van Santvoort, H., additional, Daamen, L., additional, and Molenaar, I., additional
Published: 2022
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44. Short- and Long-term Outcomes of Surgery for Pancreatic Cancer in the Elderly

Author: Henry, A.C., primary, Schouten, T., additional, Daamen, L., additional, Walma, M., additional, Noordzij, P., additional, Besselink, M., additional, Busch, O., additional, Bonsing, B., additional, Bosscha, K., additional, van Dam, R., additional, Festen, S., additional, Koerkamp, B. Groot, additional, van der Harst, E., additional, de Hingh, I., additional, Kazemier, G., additional, Liem, M., additional, de Meijer, V., additional, Nieuwenhuijs, V., additional, Roos, D., additional, Schreinemakers, J., additional, Stommel, M., additional, Molenaar, Q., additional, and van Santvoort, H., additional
Published: 2022
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45. Early Recognition and Management of Complications after Pancreatic Surgery

Author: Smits, F.J., primary, Henry, A.C., additional, Besselink, M.G., additional, Busch, O.R., additional, van Eijck, C.H., additional, Arntz, M., additional, Bollen, T.L., additional, van Delden, O.M., additional, van den Heuvel, D., additional, van der Leij, C., additional, van Lienden, K.P., additional, Moelker, A., additional, Bonsing, B.A., additional, Borel Rinkes, I.H., additional, Bosscha, K., additional, van Dam, R.M., additional, Derksen, W.J.M., additional, den Dulk, M., additional, Festen, S., additional, Groot Koerkamp, B., additional, de Haas, R.J., additional, Hagendoorn, J., additional, van der Harst, E., additional, de Hingh, I.H., additional, Kazemier, G., additional, van der Kolk, M., additional, Liem, M., additional, Lips, D.J., additional, Luyer, M.D., additional, de Meijer, V.E., additional, Mieog, J.S., additional, Nieuwenhuijs, V.B., additional, Patijn, G.A., additional, Riele, W.W. te, additional, Roos, D., additional, Schreinemakers, J.M., additional, Stommel, M.W.J., additional, Wit, F., additional, Zonderhuis, B.A., additional, Daamen, L.A., additional, van Werkhoven, C.H., additional, Molenaar, I.Q., additional, and van Santvoort, H.C., additional
Published: 2022
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46. The Impact of Complications after Resection of Pancreatic Ductal Adenocarcinoma on Disease Recurrence

Author: Henry, A.C., primary, van Goor, I., additional, Daamen, L., additional, Smits, J., additional, Nagelhout, A., additional, Besselink, M., additional, Busch, O., additional, van Eijck, C., additional, Bonsing, B., additional, Bosscha, K., additional, van Dam, R., additional, Festen, S., additional, Koerkamp, B. Groot, additional, van der Harst, E., additional, de Hingh, I., additional, van der Kolk, M., additional, Liem, M., additional, de Meijer, V., additional, Patijn, G., additional, Roos, D., additional, Schreinemakers, J., additional, Wit, F., additional, Zonderhuis, B., additional, Molenaar, Q., additional, and van Santvoort, H., additional
Published: 2022
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47. The risk of not receiving adjuvant chemotherapy after resection of pancreatic ductal adenocarcinoma

Author: Mackay, T.M., Smits, F.J., Roos, D., Bonsing, B.A., Bosscha, K., Busch, O.R., Creemers, G.J., Dam, R.M. van, Eijck, C.H.J. van, Gerhards, M.F., Groot, J.W.B. de, Koerkamp, B.G., Mohammad, N.H., Harst, E. van der, Hingh, I.H.J.T. de, Homs, M.Y.V., Kazemier, G., Liem, M.S.L., Meijer, V.E. de, Molenaar, I.Q., Nieuwenhuijs, V.B., Santvoort, H.C. van, Schelling, G.P. van der, Stommel, M.W.J., Tije, A.J. ten, Vos-Geelen, J. de, Wit, F., Wilmink, J.W., Laarhoven, H.W.M. van, Besselink, M.G., Dutch Pancreatic Canc Grp, Graduate School, AGEM - Digestive immunity, AGEM - Endocrinology, metabolism and nutrition, AGEM - Re-generation and cancer of the digestive system, CCA - Cancer Treatment and Quality of Life, Surgery, Oncology, CCA - Cancer Treatment and quality of life, Medical Oncology, Groningen Institute for Organ Transplantation (GIOT), Center for Liver, Digestive and Metabolic Diseases (CLDM), RS: NUTRIM - R2 - Liver and digestive health, MUMC+: MA Heelkunde (9), Interne Geneeskunde, MUMC+: MA Medische Oncologie (9), and RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy
Subjects: Male, SURGERY, medicine.medical_treatment, INTERNATIONAL STUDY-GROUP, 030230 surgery, SURGICAL COMPLICATIONS, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], 0302 clinical medicine, Risk Factors, Odds Ratio, Hospital Mortality, POSTOPERATIVE COMPLICATIONS, Netherlands, Gastroenterology, Age Factors, Middle Aged, Pancreaticoduodenectomy, OPEN-LABEL, CANCER, Pancreatic fistula, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, PANCREATICODUODENECTOMY, Female, medicine.drug, Carcinoma, Pancreatic Ductal, medicine.medical_specialty, Hospitals, Low-Volume, 03 medical and health sciences, Pancreatectomy, Pancreatic cancer, medicine, Journal Article, Humans, Aged, Retrospective Studies, Chemotherapy, Performance status, Hepatology, business.industry, MORTALITY, Postoperative complication, Odds ratio, medicine.disease, Gemcitabine, Surgery, Pancreatic Neoplasms, Logistic Models, DEFINITION, GEMCITABINE, Neoplasm Grading, business
Abstract: Contains fulltext : 226028.pdf (Publisher’s version ) (Closed access) BACKGROUND: The relation between type of postoperative complication and not receiving chemotherapy after resection of pancreatic ductal adenocarcinoma (PDAC) is unclear. The aim was to investigate which patient factors and postoperative complications were associated with not receiving adjuvant chemotherapy. METHODS: Patients who underwent resection (2014-2017) for PDAC were identified from the nationwide mandatory Dutch Pancreatic Cancer Audit. The association between patient-, tumor-, center-, treatment characteristics, and the risk of not receiving adjuvant chemotherapy was analyzed with multivariable logistic regression. RESULTS: Overall, of 1306 patients, 24% (n = 312) developed postoperative Clavien Dindo ≥3 complications. In-hospital mortality was 3.5% (n = 46). Some 433 patients (33%) did not receive adjuvant chemotherapy. Independent predictors (all p
Published: 2020
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48. Textbook Outcome

Author: Roessel, S. van, Mackay, T.M., Dieren, S. van, Schelling, G.P. van der, Nieuwenhutjs, V.B., Bosscha, K., Harst, E. van der, Dam, R.M. van, Liem, M.S.L., Festen, S., Stommel, M.W.J., Roos, D., Wit, F., Molenaar, I.Q., Meijer, V.E. de, Kazemier, G., Hingh, I.H.J.T. de, Santvoort, H.C. van, Bonsing, B.A., Busch, O.R., Koerkamp, B.G., Besselink, M.G., Dutch Pancreatic Canc Grp, RS: NUTRIM - R2 - Liver and digestive health, MUMC+: MA Heelkunde (9), Graduate School, CCA - Cancer Treatment and Quality of Life, AGEM - Digestive immunity, AGEM - Endocrinology, metabolism and nutrition, AGEM - Re-generation and cancer of the digestive system, Surgery, and APH - Methodology
Subjects: Male, INDICATORS, medicine.medical_treatment, INTERNATIONAL STUDY-GROUP, Logistic regression, outcomes, Gastroenterology, surgery, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], 0302 clinical medicine, Postoperative Complications, MARGIN STATUS, Medicine, IN-HOSPITAL MORTALITY, Hospital Mortality, Registries, Textbooks as Topic, pancreatic surgery, Neoadjuvant therapy, Netherlands, Response rate (survey), major complications, Incidence (epidemiology), Incidence, Middle Aged, medicine.anatomical_structure, textbook outcome, Pancreatic fistula, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Female, medicine.medical_specialty, germany, CLASSIFICATION, Pancreaticoduodenectomy, 03 medical and health sciences, Pancreatectomy, Pancreatic cancer, Internal medicine, Humans, fistula, care, Aged, Quality Indicators, Health Care, Retrospective Studies, Pancreatic duct, COMPOSITE-MEASURE, business.industry, Retrospective cohort study, medicine.disease, auditing, Pancreatic Neoplasms, business, practice variation
Abstract: Contains fulltext : 226022.pdf (Publisher’s version ) (Closed access) BACKGROUND: Textbook outcome (TO) is a multidimensional measure for quality assurance, reflecting the "ideal" surgical outcome. METHODS: Post-hoc analysis of patients who underwent pancreatoduodenectomy (PD) or distal pancreatectomy (DP) for all indications between 2014 and 2017, queried from the nationwide prospective Dutch Pancreatic Cancer Audit. An international survey was conducted among 24 experts from 10 countries to reach consensus on the requirements for TO in pancreatic surgery. Univariable and multivariable logistic regression was performed to identify TO predictors. Between-hospital variation in TO rates was compared using observed-versus-expected rates. RESULTS: Based on the survey (92% response rate), TO was defined by the absence of postoperative pancreatic fistula, bile leak, postpancreatectomy hemorrhage (all ISGPS grade B/C), severe complications (Clavien-Dindo ≥III), readmission, and in-hospital mortality. Overall, 3341 patients were included (2633 (79%) PD and 708 (21%) DP) of whom 60.3% achieved TO; 58.3% for PD and 67.4% for DP. On multivariable analysis, ASA class 3 predicted a worse TO rate after PD (ASA 3 OR 0.59 [0.44-0.80]), whereas a dilated pancreatic duct (>3 mm) and pancreatic ductal adenocarcinoma (PDAC) were associated with a better TO rate (OR 2.22 [2.05-3.57] and OR 1.36 [1.14-1.63], respectively). For DP, female sex and the absence of neoadjuvant therapy predicted better TO rates (OR 1.38 [1.01-1.90] and OR 2.53 [1.20-5.31], respectively). When comparing institutions, the observed-versus-expected rate for achieving TO varied from 0.71 to 1.46 per hospital after casemix-adjustment. CONCLUSIONS: TO is a novel quality measure in pancreatic surgery. TO varies considerably between pancreatic centers, demonstrating the potential benefit of quality assurance programs.
Published: 2020
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49. ASO Visual Abstract: Nationwide Validation of the 8th American Joint Committee on Cancer TNM Staging System and Five Proposed Modifications for Resected Pancreatic Cancer

Author: Schouten, T.J., Daamen, L.A., Dorland, G., Roessel, S.R. van, Groot, V.P., Besselink, M.G., Bonsing, B.A., Bosscha, K., Brosens, L.A.A., Busch, O.R., Dam, R.M. van, Sarasqueta, A.F., Feste, S., Koerkamp, B.G., Harst, E. van der, Hingh, I.H.J.T. de, Intven, M., Kazemier, G., Meijer, V.E. de, Nieuwenhuijs, V.B., Raicu, G.M., Roos, D., Schreinemakers, J.M.J., Stommel, M.W.J., Velthuysen, M.F. van, Verdonk, R.C., Verheij, J., Verkooijen, H.M., Santvoort, H.C. van, Molenaar, I.Q., Dutch Pancreatic Canc Grp, Surgery, and Pathology
Subjects: SDG 3 - Good Health and Well-being, Oncology, Surgery
Published: 2022
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50. Quality performance indicators in radiotherapy for early stage Hodgkinʼs lymphoma

Author: Tee, Chin H and Roos, D
Published: 2015

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